@article{PeiffersFrank2015, author = {Peiffers, Sabine and Frank, Ulrike}, title = {Der Einfluss von K{\"o}rperparametern auf das Schluckvolumen bei gesunden Erwachsenen}, series = {Spektrum Patholinguistik (Band 8) - Schwerpunktthema: Besonders behandeln? : Sprachtherapie im Rahmen prim{\"a}rer St{\"o}rungsbilder}, journal = {Spektrum Patholinguistik (Band 8) - Schwerpunktthema: Besonders behandeln? : Sprachtherapie im Rahmen prim{\"a}rer St{\"o}rungsbilder}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-79882}, pages = {239 -- 242}, year = {2015}, language = {de} } @article{PuritzSeidlFrank2011, author = {Puritz, Caroline and Seidl, Rainer Ottis and Frank, Ulrike}, title = {Die Auswirkungen des Lee Silverman Voice Treatments (LSVT) auf die kortikalen Repr{\"a}sentation der Schluckmuskulatur bei Patienten mit Morbus Parkinson}, year = {2011}, language = {de} } @article{PuritzSeidlFrank2011, author = {Puritz, Caroline and Seidl, Rainer Ottis and Frank, Ulrike}, title = {Die Auswirkungen des Lee Silverman Voice Treatments (LSVT) auf die kortikalen Repr{\"a}sentationen der Schluckmuskulatur bei Patienten mit Morbus Parkinson}, series = {Spektrum Patholinguistik}, journal = {Spektrum Patholinguistik}, number = {4}, issn = {1869-3822}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-54322}, pages = {189 -- 191}, year = {2011}, language = {de} } @phdthesis{Frank2008, author = {Frank, Ulrike}, title = {Die Behandlung tracheotomierter Patienten mit schwerer Dysphagie : eine explorative Studie zur Evaluation eines interdisziplin{\"a}ren Interventionsansatzes}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-940793-55-3}, doi = {10.25932/publishup-2451}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-20164}, school = {Universit{\"a}t Potsdam}, pages = {232}, year = {2008}, abstract = {In der neurologischen Rehabilitation werden in zunehmendem Maße tracheotomierte Patienten mit schweren Dysphagien behandelt. Daher sollte den hierzu bisher entwickelten Interventionsverfahren eine evidenzbasierte Grundlage gegeben werden. In der vorliegenden Arbeit wird ein multidisziplin{\"a}rer Behandlungsansatz zur Trachealkan{\"u}lenentw{\"o}hung und Dekan{\"u}lierung vorgestellt, der auf der Grundlage der relevanten Forschungsliteratur und klinischen Beobachtungen entwickelt wurde. Des Weiteren wird erstmals eine systematische Evaluation eines multidisziplin{\"a}ren Trachealkan{\"u}lenmangements vorgenommen und es werden explorative Daten zum Rehabilitationsverlauf dargestellt. In einem retrospektiven Vergleich wurden hierzu die Dekan{\"u}lierungs- und Komplikationsraten sowie die Dauer der Trachealkan{\"u}lenentw{\"o}hnung zweier Patientengruppen gegen{\"u}bergestellt, die vor bzw. nach Einf{\"u}hrung des beschriebenen multidisziplin{\"a}ren Trachealkan{\"u}lenmanagements im REHAB Basel, Schweiz, behandelt wurden. Der rehabilitative Verlauf der multidisziplin{\"a}r behandelten Gruppe wurde mittels der Messinstrumente FIM (Functional Independence Measure) und EFA (Early Functional Abilities) untersucht. Der Vergleich der Dekan{\"u}lierungs- und Komplikationsraten ergab eine vergleichbare Effektivit{\"a}t der beiden Behandlungsans{\"a}tze. Dar{\"u}ber hinaus zeigte sich eine signifikante Verk{\"u}rzung der Kan{\"u}lenentw{\"o}hnungsphase bei Anwendung des multidisziplin{\"a}ren Vorgehens, so dass dieses als effizenter zu beurteilen ist. Die Verlaufsanalyse der multidisziplin{\"a}r behandelten Patienten ergab erst nach der Dekan{\"u}lierung einen signifikanten Zuwachs der funktionellen Selbst{\"a}ndigkeit in Alltagsaktivit{\"a}ten. Bei der Mehrzahl der Patienten konnte ein vollst{\"a}ndiger oraler Kostaufbau nach der Dekan{\"u}lierung erreicht werden.}, language = {de} } @article{HummelFrank2010, author = {Hummel, Katja and Frank, Ulrike}, title = {Die Schluckfrequenz bei Gesunden in Seiten- vs. R{\"u}ckenlage}, series = {Spektrum Patholinguistik}, volume = {3}, journal = {Spektrum Patholinguistik}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, issn = {1866-9085}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-47077}, pages = {187 -- 190}, year = {2010}, language = {de} } @article{DrygalaWernerZoller2013, author = {Drygala, Frank and Werner, Ulrike and Zoller, Hinrich}, title = {Diet composition of the invasive raccoon dog (Nyctereutes procyonoides) and the native red fox (Vulpes vulpes) in north-east Germany}, series = {Hystrix : the Italian journal of mammalogy}, volume = {24}, journal = {Hystrix : the Italian journal of mammalogy}, number = {2}, publisher = {Associazione Teriologica Romana}, address = {Roma}, issn = {0394-1914}, doi = {10.4404/hystrix.-24.2-8867}, pages = {190 -- 194}, year = {2013}, abstract = {Invasive alien species pose a great threat to the integrity of natural communities by competition with and predation on native species. In Germany the invasive raccoon dog (Nyctereutes procyonoides) and the native red fox (Vulpes vulpes) occupy a similar ecological niche. Therefore, the aim of our study was to discover the extent of exploitative diet competition between these two generalist carnivores. Carcasses of red foxes (n=256) and raccoon dogs (n=253) were collected throughout Mecklenburg Western-Pomerania (north-east Germany) and stomachs contains were analysed. Frequency of occurrence and biomass share indicate that both canids are omnivorous and pursue opportunistic feeding strategies. Small mammals and edible plant material were the most important food resources for red foxes and raccoon dogs. Nonetheless, interspecies differences were recorded for edible plant material, small mammals and insects. While red foxes mostly feed on voles, raccoon dogs consumed mice and shrews as often as voles. Only raccoon dogs preyed on amphibians. There were no differences in carrion consumption, both species scavenged on wild boar and we found clear competition for carrion year-round. Moreover, there was evidence that two red foxes foraged on raccoon dogs and vice versa. The mean annual interspecies diet overlap index was relatively high. The diets determined for raccoon dogs and red foxes were quite similar and a similar food niche breadth was recorded. However, only minor competition is assumed to take place since differences in feeding habits do exist.}, language = {en} } @article{SchneiderKutzKapsetal.2020, author = {Schneider, Kathleen and Kutz, Anne and Kaps, Hella and Frank, Ulrike}, title = {Dysarthria Impact Profile - D}, series = {Spektrum Patholinguistik}, journal = {Spektrum Patholinguistik}, number = {12}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-479-1}, issn = {1866-9085}, doi = {10.25932/publishup-46964}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-469645}, pages = {241 -- 246}, year = {2020}, language = {de} } @article{FrankRadtkeNienstedtetal.2021, author = {Frank, Ulrike and Radtke, Julia and Nienstedt, Julie Cl{\"a}re and P{\"o}tter-Nerger, Monika and Sch{\"o}nwald, Beate and Buhmann, Carsten and Gerloff, Christian and Niessen, Almut and Fl{\"u}gel, Till and Koseki, Jana-Christiane and Pflug, Christina}, title = {Dysphagia screening in Parkinson's Disease}, series = {Neurogastroenterology and motility}, volume = {33}, journal = {Neurogastroenterology and motility}, number = {5}, publisher = {Wiley}, address = {Hoboken}, issn = {1350-1925}, doi = {10.1111/nmo.14034}, pages = {8}, year = {2021}, abstract = {Background Simple water-swallowing screening tools are not predictive of aspiration and dysphagia in patients with Parkinson's Disease (PD). We investigated the diagnostic accuracy of a multi-texture screening tool, the Gugging Swallowing Screen (GUSS) to identify aspiration and dysphagia/penetration in PD patients compared to flexible endoscopic evaluation of swallowing (FEES). Methods Swallowing function was evaluated in 51 PD participants in clinical 'on-medication' state with the GUSS and a FEES examination according to standardized protocols. Inter-rater reliability and convergent validity were determined and GUSS- and FEES-based diet recommendations were compared. Key Results Inter-rater reliability of GUSS ratings was high (r(s) = 0.8; p < 0.001). Aspiration was identified by the GUSS with a sensitivity of 50\%, and specificity of 51.35\% (PPV 28\%, NPV 73\%, LR+ 1.03, LR- 0.97), dysphagia/penetration was identified with 72.97\% sensitivity and 35.71\% specificity (PPV 75\%, NPV 33.33\%, LR+ 1.14, LR- 0.76). Agreement between GUSS- and FEES-based diet recommendations was low (r(s) = 0.12, p = 0.42) with consistent NPO (Nil per Os) allocation by GUSS and FEES in only one participant. Conclusions and Inferences The multi-texture screening tool GUSS in its current form, although applicable with good inter-rater reliability, does not detect aspiration in PD patients with acceptable accuracy. Modifications of the GUSS parameters "coughing," "voice change" and "delayed swallowing" might enhance validity. The GUSS' diet recommendations overestimate the need for oral intake restriction in PD patients and should be verified by instrumental swallowing examination.}, language = {en} } @misc{FrankRadtkeNienstedtetal.2021, author = {Frank, Ulrike and Radtke, Julia and Nienstedt, Julie Cl{\"a}re and P{\"o}tter-Nerger, Monika and Sch{\"o}nwald, Beate and Buhmann, Carsten and Gerloff, Christian and Niessen, Almut and Fl{\"u}gel, Till and Koseki, Jana-Christiane and Pflug, Christina}, title = {Dysphagia screening in Parkinson's Disease}, series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe}, journal = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe}, number = {5}, issn = {1866-8364}, doi = {10.25932/publishup-56962}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-569625}, pages = {10}, year = {2021}, abstract = {Background Simple water-swallowing screening tools are not predictive of aspiration and dysphagia in patients with Parkinson's Disease (PD). We investigated the diagnostic accuracy of a multi-texture screening tool, the Gugging Swallowing Screen (GUSS) to identify aspiration and dysphagia/penetration in PD patients compared to flexible endoscopic evaluation of swallowing (FEES). Methods Swallowing function was evaluated in 51 PD participants in clinical 'on-medication' state with the GUSS and a FEES examination according to standardized protocols. Inter-rater reliability and convergent validity were determined and GUSS- and FEES-based diet recommendations were compared. Key Results Inter-rater reliability of GUSS ratings was high (r(s) = 0.8; p < 0.001). Aspiration was identified by the GUSS with a sensitivity of 50\%, and specificity of 51.35\% (PPV 28\%, NPV 73\%, LR+ 1.03, LR- 0.97), dysphagia/penetration was identified with 72.97\% sensitivity and 35.71\% specificity (PPV 75\%, NPV 33.33\%, LR+ 1.14, LR- 0.76). Agreement between GUSS- and FEES-based diet recommendations was low (r(s) = 0.12, p = 0.42) with consistent NPO (Nil per Os) allocation by GUSS and FEES in only one participant. Conclusions and Inferences The multi-texture screening tool GUSS in its current form, although applicable with good inter-rater reliability, does not detect aspiration in PD patients with acceptable accuracy. Modifications of the GUSS parameters "coughing," "voice change" and "delayed swallowing" might enhance validity. The GUSS' diet recommendations overestimate the need for oral intake restriction in PD patients and should be verified by instrumental swallowing examination.}, language = {en} } @article{FrankFrankZimmermann2015, author = {Frank, Ulrike and Frank, Katrin and Zimmermann, Heinrich}, title = {Effects of Respiratory Therapy (bagging) on Respiratory Function, Swallowing Frequency and Vigilance in Tracheotomized Patients in Early Neurorehabilitation}, series = {Pneumologie : Zeitschrift f{\"u}r Pneumologie und Beatmungsmedizin}, volume = {69}, journal = {Pneumologie : Zeitschrift f{\"u}r Pneumologie und Beatmungsmedizin}, number = {7}, publisher = {Thieme}, address = {Stuttgart}, issn = {0934-8387}, doi = {10.1055/s-0034-1392359}, pages = {394 -- 399}, year = {2015}, abstract = {Objective: Tracheotomized patients often suffer from impairments in mucociliary clearance and limited capacities for active expectoration of secretions. We investigated the effects of a specific respiratory intervention method (bagging) for tracheotomized patients on respiratory parameters (pO(2), pCO(2), SpO(2), respiratory rates), swallowing frequency, vigilance and secretion viscosity. Methods: The bagging method supports enforced mobilization and expectoration of secretions by application of a series of manual hyperinflations with a resuscitation bag during active inspiration and manual cough support on the chest. 30 tracheotomized neurological patients participated in a multiple-baseline study including a three-weeks intervention period and a follow-up measurement three weeks after termination of the treatment. Results: Most outcome parameters improved significantly during the intervention period: pO(2) (p<.01), SpO(2) (p<.01), respiratory rates (p<.01), swallowing rates (p<.01), and vigilance scores (p<.01). The quality of bronchial secretions improved in all participants. All effects were sustained up to the follow-up measurements. Conclusion: This preliminary data indicates positive effects for a respiratory intervention method (bagging) on respiratory function and additional respiration-related functions in tracheotomized neurological patients. This easy-to-learn and inexpensive method might expand the range of treatment options for tracheotomized and non-responsive patients.}, language = {en} } @article{JaeckelFrank2012, author = {J{\"a}ckel, Annemarie and Frank, Ulrike}, title = {Effekte des Mendelsohn Man{\"o}vers auf die Atem-Schluck-Koordination : eine Untersuchung der intra- individuellen Variation bei gesunden Erwachsenen}, year = {2012}, language = {de} } @misc{JaeckelFrank2012, author = {J{\"a}ckel, Annemarie and Frank, Ulrike}, title = {Effekte des Mendelsohn Man{\"o}vers auf die Atem-Schluck-Koordination : eine Untersuchung der intra-individuellen Variation bei gesunden Erwachsenen}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-62491}, year = {2012}, abstract = {1 Einleitung 2 Fragestellungen 3 Methode 4 Ergebnisse und Diskussion 5 Literatur}, language = {de} } @article{FrankFrankZimmermann2015, author = {Frank, Ulrike and Frank, Katrin and Zimmermann, Heinrich}, title = {Effekte einer spezifischen Atemtherapie (Bagging) auf die Atem- und Schluckfunktion bei tracheotomierten Patienten}, series = {Spektrum Patholinguistik (Band 8) - Schwerpunktthema: Besonders behandeln? : Sprachtherapie im Rahmen prim{\"a}rer St{\"o}rungsbilder}, journal = {Spektrum Patholinguistik (Band 8) - Schwerpunktthema: Besonders behandeln? : Sprachtherapie im Rahmen prim{\"a}rer St{\"o}rungsbilder}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-79873}, pages = {235 -- 237}, year = {2015}, language = {de} } @misc{LeitnerBaronClarketal.2005, author = {Leitner, Ulrike and Baron, Frank and Clark, Rex and Doherr, Detlev and Griep, Wolfgang and Schn{\"o}pf, Markus}, title = {HiN : Alexander von Humboldt im Netz = Humboldt Digital Library}, volume = {VI}, number = {10}, editor = {Ette, Ottmar and Knobloch, Eberhard}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, issn = {1617-5239}, doi = {10.18443/hinvol6iss102005}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-35175}, pages = {82}, year = {2005}, abstract = {- Ulrike Leitner: Einleitung - Frank Baron: From Alexander von Humboldt to Frederic Edwin Church: Voyages of Scientific Exploration and Artistic Creativity - Rex Clark: Alexander von Humboldt's Images of Landscape and the ‚Chaos of the Poets - Detlev Doherr: The Humboldt Digital Library: Exploring Innovative Structures - Wolfgang Griep: Die Bedeutung der Umkreisquellen f{\"u}r Alexander von Humboldts s{\"u}damerikanische Reise - Ulrike Leitner: Vielschichtigkeit und Komplexit{\"a}t im Reisewerk Alexander von Humboldts - Bibliographischer Hintergrund - Markus Schnoepf: El Proyecto Humboldt: Una biblioteca digital para las expediciones cient{\´i}ficas a las Islas Canarias}, language = {de} } @misc{EtteKnoblochSchwarzetal.2014, author = {Ette, Ottmar and Knobloch, Eberhard and Schwarz, Oliver and Werner, Petra and Suckow, Christian and Jobst, Anne and Schmuck, Thomas and Ringmacher, Manfred and Tintemann, Ute and Leitner, Ulrike and Holl, Frank and Panwitz, Sebastian and P{\´e}aud, Laura and Holtz, B{\"a}rbel and Folkerts, Menso and P{\"a}ßler, Ulrich and Roba, Bill}, title = {HiN : Alexander von Humboldt im Netz = Ingo Schwarz zum 65. Geburtstag}, series = {HIN : Alexander von Humboldt im Netz ; international review for Humboldtian studies}, volume = {XV}, journal = {HIN : Alexander von Humboldt im Netz ; international review for Humboldtian studies}, number = {29}, editor = {Ette, Ottmar and Knobloch, Eberhard}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, issn = {1617-5239}, doi = {10.18443/hinvol15iss292014}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-85033}, pages = {201}, year = {2014}, abstract = {Inhalt: Alexander von Humboldt-Forschungsstelle: Ingo Schwarz zum 65. Geburtstag Ottmar Ette: Findung und Erfindung einer Leserschaft. Neuere Editionsprojekte zu Alexander von Humboldt als Grundlage und Herausforderung k{\"u}nftigen Forschens Eberhard Knobloch: Alexandre de Humboldt et le Marquis de Laplace Oliver Schwarz: Alexander von Humboldt als astronomischer Arbeiter, Diskussionspartner und Ideengeber Petra Werner: Innenwelten und bleiche G{\"a}rten. Alexander von Humboldt untertage und in der Caripe-H{\"o}hle Christian Suckow: Alexander von Humboldt in Ust'-Kamenogorsk Anne Jobst: Neue Briefe Christian Gottfried Ehrenbergs an Alexander von Humboldt Thomas Schmuck: Humboldt, Baer und die Evolution Manfred Ringmacher: Zwei Briefe auf Guaran{\´i} in Alexander von Humboldts Handschrift Ute Tintemann: Julius Klaproths Mithridates-Projekt, Alexander von Humboldt und das Verlagshaus Cotta Ulrike Leitner: „Ja! Wenn Berlin Bonn w{\"a}re!" Friedrich R{\"u}ckerts Berufung nach Berlin Frank Holl: „Zur Freiheit bestimmt" - Alexander von Humboldts Blick auf die Kulturen der Welt Sebastian Panwitz: Das Humboldt-Mendelssohn-Haus J{\"a}gerstraße 22. Ein Quellenfund Laura P{\´e}aud: Du Mexique {\`a} l'Oural : l'expertise humboldtienne au service du politique B{\"a}rbel Holtz: „Cicerone" des K{\"o}nigs? Alexander von Humboldt und Friedrich Wilhelm III. Menso Folkerts: Ein unerwartetes Zusammentreffen in Sanssouci. Alexander von Humboldt und Karl Ludwig Hencke an der Tafel Friedrich Wilhelms IV. Ulrich P{\"a}ßler: Preußens Mann in Washington. F{\"u}nf Briefe Friedrich von Gerolts an Alexander von Humboldt (1858/1859) Bill Roba: German-Iowan Strategies in Celebrating the Centennial of Alexander von Humboldt's Birth Regina Mikosch: Ingo Schwarz' Ver{\"o}ffentlichungen zur Alexander von Humboldt {\"U}ber die Autoren}, language = {mul} } @article{NeuschaeferRubeEngemaierKochetal.2003, author = {Neusch{\"a}fer-Rube, Frank and Engemaier, Eva and Koch, Sina and B{\"o}er, Ulrike and P{\"u}schel, Gerhard Paul}, title = {Identification by site-directed mutagenesis of amino acids contributing to ligand-binding specificity or signal transduction properties of the human FP prostanoid receptor}, year = {2003}, abstract = {Prostanoid receptors belong to the class of heptahelical plasma membrane receptors. For the five prostanoids, eight receptor subtypes have been identified. They display an overall sequence similarity of roughly 30\%. Based on sequence comparison, single amino acids in different subtypes of different species have previously been identified by site-directed mutagenesis or in hybrid receptors that appear to be essential for ligand binding or G-protein coupling. Based on this information, a series of mutants of the human FP receptor was generated and characterized in ligand- binding and second-messenger-formation studies. It was found that mutation of His-81 to Ala in transmembrane domain 2 and of Arg-291 to Leu in transmembrane domain 7, which are putative interaction partners for the prostanoid's carboxyl group, abolished ligand binding. Mutants in which Ser-263 in transmembrane domain 6 or Asp-300 in transmembrane domain 7 had been replaced by Ala or Gln, respectively, no longer discriminated between prostaglandins PGF(2alpha) and PGD(2). Thus distortion of the topology of transmembrane domains 6 and 7 appears to interfere with the cyclopentane ring selectivity of the receptor. PGF(2alpha)-induced inositol formation was strongly reduced in the mutant Asp-300Gln, inferring a role for this residue in agonist-induced G-protein activation.}, language = {en} } @article{FrankvandenEngelHoekNogueiraetal.2018, author = {Frank, Ulrike and van den Engel-Hoek, Lenie and Nogueira, Dalia and Schindler, Antonio and Adams, Sasha and Curry, Morgan and Huckabee, Maggie-Lee}, title = {International standardisation of the test of masticating and swallowing solids in children}, series = {Journal of oral rehabilitation}, volume = {46}, journal = {Journal of oral rehabilitation}, number = {2}, publisher = {Wiley}, address = {Hoboken}, issn = {0305-182X}, doi = {10.1111/joor.12728}, pages = {161 -- 169}, year = {2018}, abstract = {The Test of Masticating and Swallowing Solids (TOMASS) is a validated assessment tool measuring the efficiency of solid bolus intake by four quantitative parameters: discrete bites, masticatory cycles, swallows and time to ingest a single cracker. A normative database for adults (20-80+ years) has previously been established. The objective of this study was to investigate the applicability and reliability of the TOMASS in children and adolescents (TOMASS-C) and to establish the normative database for this younger population. We collected data from 638 participants (male: 311, female: 327) in five age groups (4-18 years) with five different but very similar test crackers in four countries. Significant effects of bolus type (cracker), age group and gender on the TOMASS parameters were identified, requiring stratification of the TOMASS-C database by these variables. Intra-rater reliability was excellent (ICC > 0.94) for all parameters; inter-rater reliability was moderate for "number of swallows" (ICC = 0.54), good for "bites" (ICC = 0.78) and "time" (ICC = 0.82), and excellent for "masticatory cycles" (ICC = 0.96). The "Test of Masticating and Swallowing Solids in Children (TOMASS-C)" was identified to be a reliable diagnostic tool for the comprehensive measurement of discrete oral stage components of solid bolus ingestion, standardised by a large normative database that covers age groups from preschoolers to young adults. While differences between gender groups were less pronounced than in the adult population, previous results relating to changes in masticatory and swallowing as a function of age are confirmed by our data.}, language = {en} } @article{MuellerBeerFrank2022, author = {M{\"u}ller, Nina and Beer, Carola de and Frank, Ulrike}, title = {Ist die therapeutische Mundpflege bei Dysphagiepatient*innen verschwendete Zeit?}, series = {Sprache, Stimme, Geh{\"o}r : Zeitschrift f{\"u}r Kommunikationsst{\"o}rungen}, volume = {46}, journal = {Sprache, Stimme, Geh{\"o}r : Zeitschrift f{\"u}r Kommunikationsst{\"o}rungen}, number = {03}, publisher = {Thieme}, address = {Stuttgart}, issn = {0342-0477}, doi = {10.1055/a-1714-1587}, pages = {150 -- 155}, year = {2022}, abstract = {Aspirationspneumonien sind eine h{\"a}ufige Todesursache bei Dysphagiepatient*innen. In diesem Beitrag wird durch die Evaluation relevanter Studien die Frage untersucht, ob die therapeutische Mundpflege bei Dysphagiepatient*innen zur Verringerung des Pneumonierisikos beitragen kann. Zudem wird auf dieser Grundlage eine Handlungsempfehlung f{\"u}r die Umsetzung der Mundpflege entwickelt. Die ausgew{\"a}hlten Studien zeigen, dass die Mundpflege einen positiven Effekt auf das Pneumonie-Risiko von Dysphagiepatient*innen hat. Sie sollte auf den Grunds{\"a}tzen Einfachheit, Sicherheit, Arbeitskr{\"a}fteentlastung, Wirksamkeit, Universalit{\"a}t, Wirtschaftlichkeit und vollst{\"a}ndige Mundpflege aller Teile der Mundh{\"o}hle beruhen und nimmt weniger als f{\"u}nf Minuten t{\"a}glich ein. Sie bereitet durch die taktile Stimulation auf die anschließende Dysphagie-Therapie vor und ist somit sinnvoll investierte Therapiezeit.}, language = {de} } @article{OpitzWuennemannAichneretal.2012, author = {Opitz, Stephan and W{\"u}nnemann, Bernd and Aichner, Bernhard and Dietze, Elisabeth and Hartmann, Kai and Herzschuh, Ulrike and IJmker, Janneke and Lehmkuhl, Frank and Li, Shijie and Mischke, Steffen and Plotzki, Anna and Stauch, Georg and Diekmann, Bernhard}, title = {Late Glacial and Holocene development of Lake Donggi Cona, north-eastern Tibetan Plateau, inferred from sedimentological analysis}, series = {Palaeogeography, palaeoclimatology, palaeoecology : an international journal for the geo-sciences}, volume = {337}, journal = {Palaeogeography, palaeoclimatology, palaeoecology : an international journal for the geo-sciences}, number = {23}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0031-0182}, doi = {10.1016/j.palaeo.2012.04.013}, pages = {159 -- 176}, year = {2012}, abstract = {Sediments of Lake Donggi Cona on the northeastern Tibetan Plateau were studied to infer changes in the lacustrine depositional environment, related to climatic and non-climatic changes during the last 19 kyr. The lake today fills a 30x8 km big and 95 m deep tectonic basin, associated with the Kunlun Fault. The study was conducted on a sediment-core transect through the lake basin, in order to gain a complete picture of spatio-temporal environmental change. The recovered sediments are partly finely laminated and are composed of calcareous muds with variable amounts of carbonate micrite, organic matter, detrital silt and clay. On the basis of sedimentological, geochemical, and mineralogical data up to five lithological units (LU) can be distinguished that document distinct stages in the development of the lake system. The onset of the lowermost LU with lacustrine muds above basal sands indicates that lake level was at least 39 m below the present level and started to rise after 19 ka, possibly in response to regional deglaciation. At this time, the lacustrine environment was characterized by detrital sediment influx and the deposition of siliciclastic sediment. In two sediment cores, upward grain-size coarsening documents a lake-level fall after 13 cal ka BP, possibly associated with the late-glacial Younger Dryas stadial. From 11.5 to 4.3 cal ka BP, grain-size fining in sediment cores from the profundal coring sites and the onset of lacustrine deposition at a litoral core site (2 m water depth) in a recent marginal bay of Donggi Cona document lake-level rise during the early to mid-Holocene to at least modern level. In addition, high biological productivity and pronounced precipitation of carbonate micrites are consistent with warm and moist climate conditions related to an enhanced influence of summer monsoon. At 4.3 cal ka BP the lake system shifted from an aragonite- to a calcite-dominated system, indicating a change towards a fully open hydrological lake system. The younger clay-rich sediments are moreover non-laminated and lack any diagenetic sulphides, pointing to fully ventilated conditions, and the prevailing absence of lake stratification. This turning point in lake history could imply either a threshold response to insolation-forced climate cooling or a response to a non-climatic trigger, such as an erosional event or a tectonic pulse that induced a strong earthquake, which is difficult to decide from our data base.}, language = {en} } @article{SchirrmeisterMeyerAndreevetal.2016, author = {Schirrmeister, Lutz and Meyer, Hanno and Andreev, Andrei and Wetterich, Sebastian and Kienast, Frank and Bobrov, Anatoly and Fuchs, Margret and Sierralta, Melanie and Herzschuh, Ulrike}, title = {Late Quaternary paleoenvironmental records from the Chatanika River valley near Fairbanks (Alaska)}, series = {Quaternary science reviews : the international multidisciplinary research and review journal}, volume = {147}, journal = {Quaternary science reviews : the international multidisciplinary research and review journal}, publisher = {Elsevier}, address = {Oxford}, issn = {0277-3791}, doi = {10.1016/j.quascirev.2016.02.009}, pages = {259 -- 278}, year = {2016}, abstract = {Perennially-frozen deposits are considered as excellent paleoenvironmental archives similar to lacustrine, deep marine, and glacier records because of the long-term and good preservation of fossil records under stable permafrost conditions. A permafrost tunnel in the Vault Creek Valley (Chatanika River Valley, near Fairbanks) exposes a sequence of frozen deposits and ground ice that provides a comprehensive set of proxies to reconstruct the late Quaternary environmental history of Interior Alaska. The multi-proxy approach includes different dating techniques (radiocarbon-accelerator mass spectrometry [AMS C-14], optically stimulated luminescence [OSL], thorium/uranium radioisotope disequilibria [Th-230/U]), as well as methods of sedimentology, paleoecology, hydrochemistry, and stable isotope geochemistry of ground ice. The studied sequence consists of 36-m-thick late Quaternary deposits above schistose bedrock. Main portions of the sequence accumulated during the early and middle Wisconsin periods. The lowermost unit A consists of about 9-m-thick ice-bonded fluvial gravels with sand and peat lenses. A late Sangamon (MIS 5a) age of unit A is assumed. Spruce forest with birch, larch, and some shrubby alder dominated the vegetation. High presence of Sphagnum spores and Cyperaceae pollen points to mires in the Vault Creek Valley. The overlying unit B consists of 10-m-thick alternating fluvial gravels, loess-like silt, and sand layers, penetrated by small ice wedges. OSL dates support a stadial early Wisconsin (MIS 4) age of unit B. Pollen and plant macrofossil data point to spruce forests with some birch interspersed with wetlands around the site. The following unit C is composed of 15-m-thick ice-rich loess-like and organic-rich silt with fossil bones and large ice wedges. Unit C formed during the interstadial mid-Wisconsin (MIS 3) and stadial late Wisconsin (MIS 2) as indicated by radiocarbon ages. Post-depositional slope processes significantly deformed both, ground ice and sediments of unit C. Pollen data show that spruce forests and wetlands dominated the area. The macrofossil remains of Picea, Larix, and Alnus incana ssp. tenuifolia also prove the existence of boreal coniferous forests during the mid-Wisconsin interstadial, which were replaced by treeless tundra-steppe vegetation during the late Wisconsin stadial. Unit C is discordantly overlain by the 2-m-thick late Holocene deposits of unit D. The pollen record of unit D indicates boreal forest vegetation similar to the modern one. The permafrost record from the Vault Creek tunnel reflects more than 90 ka of periglacial landscape dynamics triggered by fluvial and eolian accumulation, and formation of ice-wedge polygons and post depositional deformation by slope processes. The record represents a typical Wisconsin valley-bottom facies in Central Alaska. (C) 2016 Elsevier Ltd. All rights reserved.}, language = {en} }