@article{KatagiriHasegawaFujikuraetal.2016, author = {Katagiri, Yohei and Hasegawa, Junko and Fujikura, Ushio and Hoshino, Rina and Matsunaga, Sachihiro and Tsukaya, Hirokazu}, title = {The coordination of ploidy and cell size differs between cell layers in leaves}, series = {Development : Company of Biologists}, volume = {143}, journal = {Development : Company of Biologists}, publisher = {Company of Biologists Limited}, address = {Cambridge}, issn = {0950-1991}, doi = {10.1242/dev.130021}, pages = {1120 -- 1125}, year = {2016}, abstract = {Growth and developmental processes are occasionally accompanied by multiple rounds of DNA replication, known as endoreduplication. Coordination between endoreduplication and cell size regulation often plays a crucial role in proper organogenesis and cell differentiation. Here, we report that the level of correlation between ploidy and cell volume is different in the outer and inner cell layers of leaves of Arabidopsis thaliana using a novel imaging technique. Although there is a well-known, strong correlation between ploidy and cell volume in pavement cells of the epidermis, this correlation was extremely weak in palisade mesophyll cells. Induction of epidermis cell identity based on the expression of the homeobox gene ATML1 in mesophyll cells enhanced the level of correlation between ploidy and cell volume to near that of wild-type epidermal cells. We therefore propose that the correlation between ploidy and cell volume is regulated by cell identity.}, language = {en} } @article{TsukayaByrneHoriguchietal.2013, author = {Tsukaya, Hirokazu and Byrne, Mary E. and Horiguchi, Gorou and Sugiyama, Munetaka and Van Lijsebettens, Mieke and Lenhard, Michael}, title = {How do 'housekeeping' genes control organogenesis?-unexpected new findings on the role of housekeeping genes in cell and organ differentiation}, series = {Journal of plant research}, volume = {126}, journal = {Journal of plant research}, number = {1}, publisher = {Springer}, address = {Tokyo}, issn = {0918-9440}, doi = {10.1007/s10265-012-0518-2}, pages = {3 -- 15}, year = {2013}, abstract = {In recent years, an increasing number of mutations in what would appear to be 'housekeeping genes' have been identified as having unexpectedly specific defects in multicellular organogenesis. This is also the case for organogenesis in seed plants. Although it is not surprising that loss-of-function mutations in 'housekeeping' genes result in lethality or growth retardation, it is surprising when (1) the mutant phenotype results from the loss of function of a 'housekeeping' gene and (2) the mutant phenotype is specific. In this review, by defining housekeeping genes as those encoding proteins that work in basic metabolic and cellular functions, we discuss unexpected links between housekeeping genes and specific developmental processes. In a surprising number of cases housekeeping genes coding for enzymes or proteins with functions in basic cellular processes such as transcription, post-transcriptional modification, and translation affect plant development.}, language = {en} }