@article{SchwarzeKellingMuelleretal.2012, author = {Schwarze, Thomas and Kelling, Alexandra and M{\"u}ller, Holger and Trautmann, Michael and Klamroth, Tillmann and Baumann, Otto and Strauch, Peter and Holdt, Hans-J{\"u}rgen}, title = {N-2-Pyridinylmethyl-N '-arylmethyl-diaminomaleonitriles: New Highly Selective Chromogenic Chemodosimeters for Copper(II)}, series = {Chemistry - a European journal}, volume = {18}, journal = {Chemistry - a European journal}, number = {34}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0947-6539}, doi = {10.1002/chem.201201731}, pages = {10506 -- 10510}, year = {2012}, language = {en} } @article{DebatinThomasKellingetal.2010, author = {Debatin, Franziska and Thomas, Arne and Kelling, Alexandra and Hedin, Niklas and Bacsik, Zoltan and Senkovska, Irena and Kaskel, Stefan and Junginger, Matthias and M{\"u}ller, Holger and Schilde, Uwe and J{\"a}ger, Christian and Friedrich, Alwin and Holdt, Hans-J{\"u}rgen}, title = {In situ synthesis of an imidazolate-4-amide-5-imidate ligand and formation of a microporous zinc-organic framework with H2-and CO2-storage ability}, issn = {1433-7851}, doi = {10.1002/anie.200906188}, year = {2010}, abstract = {Narrow channels with polar walls are the structural and functional features responsible for the high capacity of a zinc-organic framework based on an imidazolate-amide-imidate ligand for the uptake of H2 and CO2 (see structure: orange Zn, blue N, red O, dark gray C, light gray H). The rigid and stable chelating ligand was synthesized in situ by partial hydrolysis of a dicyanoimidazole compound.}, language = {en} } @article{SchwarzeRiemerMuelleretal.2019, author = {Schwarze, Thomas and Riemer, Janine and M{\"u}ller, Holger and John, Leonard and Holdt, Hans-J{\"u}rgen and Wessig, Pablo}, title = {Na+ Selective Fluorescent Tools Based on Fluorescence Intensity Enhancements, Lifetime Changes, and on a Ratiometric Response}, series = {Chemistry - a European journal}, volume = {25}, journal = {Chemistry - a European journal}, number = {53}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0947-6539}, doi = {10.1002/chem.201902536}, pages = {12412 -- 12422}, year = {2019}, abstract = {Over the years, we developed highly selective fluorescent probes for K+ in water, which show K+-induced fluorescence intensity enhancements, lifetime changes, or a ratiometric behavior at two emission wavelengths (cf. Scheme 1, K1-K4). In this paper, we introduce selective fluorescent probes for Na+ in water, which also show Na+ induced signal changes, which are analyzed by diverse fluorescence techniques. Initially, we synthesized the fluorescent probes 2, 4, 5, 6 and 10 for a fluorescence analysis by intensity enhancements at one wavelength by varying the Na+ responsive ionophore unit and the fluorophore moiety to adjust different K-d values for an intra- or extracellular Na+ analysis. Thus, we found that 2, 4 and 5 are Na+ selective fluorescent tools, which are able to measure physiologically important Na+ levels at wavelengths higher than 500 nm. Secondly, we developed the fluorescent probes 7 and 8 to analyze precise Na+ levels by fluorescence lifetime changes. Herein, only 8 (K-d=106 mm) is a capable fluorescent tool to measure Na+ levels in blood samples by lifetime changes. Finally, the fluorescent probe 9 was designed to show a Na+ induced ratiometric fluorescence behavior at two emission wavelengths. As desired, 9 (K-d=78 mm) showed a ratiometric fluorescence response towards Na+ ions and is a suitable tool to measure physiologically relevant Na+ levels by the intensity change of two emission wavelengths at 404 nm and 492 nm.}, language = {en} } @misc{SchwarzeMuellerAstetal.2014, author = {Schwarze, Thomas and M{\"u}ller, Holger and Ast, Sandra and Steinbr{\"u}ck, D{\"o}rte and Eidner, Sascha and Geißler, Felix and Kumke, Michael Uwe and Holdt, Hans-J{\"u}rgen}, title = {Fluorescence lifetime-based sensing of sodium by an optode}, publisher = {The Royal Society of Chemistry}, address = {Cambridge}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-76785}, pages = {14167 -- 14170}, year = {2014}, abstract = {We report a 1,2,3-triazol fluoroionophore for detecting Na+ that shows in vitro enhancement in the Na+-induced fluorescence intensity and decay time. The Na+-selective molecule 1 was incorporated into a hydrogel as a part of a fiber optical sensor. This sensor allows the direct determination of Na+ in the range of 1-10 mM by measuring reversible fluorescence decay time changes.}, language = {en} } @book{MuellerNagelPetersen1996, author = {M{\"u}ller, Klaus and Nagel, Thomas and Petersen, Hans-Georg}, title = {{\"O}kosteuerreform und Senkung der direkten Abgaben : zu einer Neugestaltung des deutschen Steuer- und Transfersystems}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-16116}, publisher = {Universit{\"a}t Potsdam}, year = {1996}, abstract = {Aus der Einleitung: Angesichts der erkannten Defizite des deutschen Steuer- und Transfersystems r{\"u}cken Forderungen nach einer grundlegenden Umgestaltung in j{\"u}ngster Vergangenheit verst{\"a}rkt in das Zentrum der {\"o}ffentlichen Diskussion. So werden einerseits infolge der zahlreichen verfassungsgerichtlichen {\"A}nderungsvorgaben neben der bereits in Angriff genommenen einkommensteuerlichen Freistellung des Existenzminimums auch vielf{\"a}ltige Anpassungen in Verm{\"o}gen-, Erbschaft- und Grundsteuern notwendig. Gleichzeitig erscheinen Maßnahmen zur Verbesserung der Anreizstruktur erforderlich, die wiederum erhebliche R{\"u}ckwirkungen auf die zuk{\"u}nftige Struktur des Einkommensteuertarifs (insbesondere dessen Grenzsteuersatzverlauf) haben d{\"u}rften. Andererseits forciert die Vielzahl der festzustellenden Umweltprobleme die Forderung nach einer instrumentalen Neuorientierung mit verst{\"a}rkter Betonung des Einsatzes von Lenkungsabgaben. Zur Verwendung der aus umweltorientierten Abgaben resultierenden Einnahmen wird vorgeschlagen, diese in gleicher H{\"o}he in Form kompensierender Senkungen der Einkommensteuer an die Steuerpflichtigen weiterzugeben, so daß eine Erh{\"o}hung der volkswirtschaftlichen Steuerquote ausgeschlossen wird. Diese Umstrukturierung des Steuersystems weg von direkten und hin zu indirekten Steuern ließe sich zugleich verbinden mit einer allgemeinen Sicherung eines Grundeinkommens in der Form, daß die existierende Sozialhilfe durch eine "Negative Einkommensteuer" ersetzt w{\"u}rde. Diese Fundamentalreform des Steuerund Transfersystems k{\"o}nnte nicht nur zu einer wesentlichen Verbesserung {\"o}konomischer Anreizwirkungen beitragen, sondern zugleich {\"u}ber die ausgel{\"o}sten Lenkungswirkungen zu einer modernen, {\"o}kologieorientierten Wirtschaftsstruktur f{\"u}hren. Als Kompensationsmaßnahmen sind auch nachhaltige Verringerungen der Lohnnebenkosten denkbar, die die Standortbedingungen f{\"u}r die Unternehmen in Deutschland deutlich verbessern k{\"o}nnten.}, language = {de} } @book{KloseNoldeEichholzetal.2008, author = {Klose, Dagmar and Nolde, Bettina and Eichholz, Nicole and Nolde, Bettina and Engelland, Christian and Kroggel, Petra and Kunde, Christine and Pirska, Maya and St{\"a}hr, Anne and Flechsig, Thomas and Lehmann, Andrea and Petersen, Anne and Siekmann, Katja and Bielick, Jakob and Skerra, Arne and Bonnet, Florian and Klemmt, Gregor and Wagner, Anne and M{\"u}ller, Andreas and Schurmann, Angela}, title = {Die Grundlegung der modernen Welt in der Antike : Lehrerhandreiche f{\"u}r den Geschichtsunterricht nach neuem Rahmenlehrplan f{\"u}r die Sekundarstufe II Berlin-Brandenburg}, editor = {Klose, Dagmar}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-939469-96-4}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-15298}, publisher = {Universit{\"a}t Potsdam}, pages = {291}, year = {2008}, abstract = {Ein neues Ziel-Inhalts-Konzept des Rahmenlehrplans nimmt in dieser Lehrerhandreiche Gestalt an. Fachwissenschaftliche und didaktische Instruktionen sowie ein ideenreicher Arbeitsteil (Materialien und Aufgaben) helfen bei der Unterrichtsvorbereitung. Aus dem Inhalt: - ein integratives Antike-Projekt untersucht M{\"o}glichkeiten und Grenzen gesellschaftlicher Teilhabe in Athen und der r{\"o}mischen Republik; - Augustus und Alexander als Zentralgestalten universaler Monarchie und Reichsbildung werden in der biografischen Rekonstruktion und im historischen Kontext lebendig; - das Thema Erinnerungskultur in der Antike und heute verweist auf Grundprobleme der Geschichtskultur; - Anregungen zur Arbeit mit dem Spielfilm „Alexander" als historische Quelle f{\"u}hren an rezeptionsgeschichtliche und medienspezifische Aspekte historischen Lernens heran}, language = {de} } @article{GrimmMeyerCzaplaetal.2013, author = {Grimm, Christiane and Meyer, Thomas and Czapla, Sylvia and Nikolaus, J{\"o}rg and Scheidt, Holger A. and Vogel, Alexander and Herrmann, Andreas and Wessig, Pablo and Huster, Daniel and M{\"u}ller, Peter}, title = {Structure and dynamics of molecular rods in membranes application of a Spin-Labeled rod}, series = {Chemistry - a European journal}, volume = {19}, journal = {Chemistry - a European journal}, number = {8}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0947-6539}, doi = {10.1002/chem.201202500}, pages = {2703 -- 2710}, year = {2013}, abstract = {Molecular rods consisting of a hydrophobic backbone and terminally varying functional groups have been synthesized for applications for the functionalization of membranes. In the present study, we employ a spin-labeled analogue of a recently described new class of molecular rods to characterize their dynamic interactions with membranes. By using the different approaches of ESR and NMR spectroscopy, we show that the spin moiety of the membrane-embedded spin-labeled rod is localized in the upper chain/glycerol region of membranes of different compositions. The rod is embedded within the membrane in a tilted orientation to adjust for the varying hydrophobic thicknesses of these bilayers. This orientation does not perturb the membrane structure. The water solubility of the rod is increased significantly in the presence of certain cyclodextrins. These cyclodextrins also allow the rods to be extracted from the membrane and incorporated into preformed membranes. The latter will improve the future applications of these rods in cellular systems as stable membrane-associated anchors for the functionalization of membrane surfaces.}, language = {en} } @article{PetersenMuellerNagel1998, author = {Petersen, Hans-Georg and M{\"u}ller, Klaus and Nagel, Thomas}, title = {Mineral{\"o}lsteuererh{\"o}hung und kompensatorische Einkommensteuersenkung. Simulation der Verteilungseffekte in einem mikro{\"o}konomischen Gruppensimulationsmodell}, issn = {0023-3498}, year = {1998}, language = {de} } @article{HlinakMuellerKrameretal.1998, author = {Hlinak, Andreas and M{\"u}ller, Thomas and Kramer, Matthias and M{\"u}hle, Ralf-Udo and Liebherr, Helga and Ziedler, Klaus}, title = {Serological survey of viral pathogens in bean and white-fronted geese from Germany}, issn = {0090-3558}, year = {1998}, language = {en} } @article{JedrusikBodeStudenckaSmolkaetal.2013, author = {Jedrusik-Bode, Monika and Studencka, Maja and Smolka, Christian and Baumann, Tobias and Schmidt, Henning and Kampf, Jan and Paap, Franziska and Martin, Sophie and Tazi, Jamal and M{\"u}ller, Kristian M. and Kr{\"u}ger, Marcus and Braun, Thomas and Bober, Eva}, title = {The sirtuin SIRT6 regulates stress granule formation in C. elegans and mammals}, series = {Journal of cell science}, volume = {126}, journal = {Journal of cell science}, number = {22}, publisher = {Company of Biologists Limited}, address = {Cambridge}, issn = {0021-9533}, doi = {10.1242/jcs.130708}, pages = {5166 -- +}, year = {2013}, abstract = {SIRT6 is a NAD(+)-dependent deacetylase that modulates chromatin structure and safeguards genomic stability. Until now, SIRT6 has been assigned to the nucleus and only nuclear targets of SIRT6 are known. Here, we demonstrate that in response to stress, C. elegans SIR-2.4 and its mammalian orthologue SIRT6 localize to cytoplasmic stress granules, interact with various stress granule components and induce their assembly. Loss of SIRT6 or inhibition of its catalytic activity in mouse embryonic fibroblasts impairs stress granule formation and delays disassembly during recovery, whereas deficiency of SIR-2.4 diminishes maintenance of P granules and decreases survival of C. elegans under stress conditions. Our findings uncover a novel, evolutionary conserved function of SIRT6 in the maintenance of stress granules in response to stress.}, language = {en} }