@misc{MorelCastroFossatietal.2014, author = {Morel, T. and Castro, Norberto and Fossati, Luca and Hubrig, Swetlana and Langer, N. and Przybilla, Norbert and Sch{\"o}ller, Markus and Carroll, Thorsten Anthony and Ilyin, Ilya and Irrgang, Andreas and Oskinova, Lida and Schneider, Fabian R. N. and Simon D{\´i}az, Sergio and Briquet, Maryline and Gonz{\´a}lez, Jean-Francois and Kharchenko, Nina and Nieva, M.-F. and Scholz, Ralf-Dieter and de Koter, Alexander and Hamann, Wolf-Rainer and Herrero, Artemio and Ma{\´i}z Apell{\´a}niz, Jesus and Sana, Hugues and Arlt, Rainer and Barb{\´a}, Rodolfo H. and Dufton, Polly and Kholtygin, Alexander and Mathys, Gautier and Piskunov, Anatoly E. and Reisenegger, Andreas and Spruit, H. and Yoon, S.-C.}, title = {The B fields in OB stars (BOB) survey}, series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, number = {821}, issn = {1866-8372}, doi = {10.25932/publishup-41523}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-415238}, pages = {8}, year = {2014}, abstract = {The B fields in OB stars (BOB) survey is an ESO large programme collecting spectropolarimetric observations for a large number of early-type stars in order to study the occurrence rate, properties, and ultimately the origin of magnetic fields in massive stars. As of July 2014, a total of 98 objects were observed over 20 nights with FORS2 and HARPSpol. Our preliminary results indicate that the fraction of magnetic OB stars with an organised, detectable field is low. This conclusion, now independently reached by two different surveys, has profound implications for any theoretical model attempting to explain the field formation in these objects. We discuss in this contribution some important issues addressed by our observations (e.g., the lower bound of the field strength) and the discovery of some remarkable objects.}, language = {en} } @article{FoerstnerBoettgerMoldavskietal.2023, author = {F{\"o}rstner, Bernd Rainer and B{\"o}ttger, Sarah Jane and Moldavski, Alexander and Bajbouj, Malek and Pfennig, Andrea and Manook, Andre and Ising, Marcus and Pittig, Andre and Heinig, Ingmar and Heinz, Andreas and Mathiak, Klaus and Schulze, Thomas G. and Schneider, Frank and Kamp-Becker, Inge and Meyer-Lindenberg, Andreas and Padberg, Frank and Banaschewski, Tobias and Bauer, Michael and Rupprecht, Rainer and Wittchen, Hans-Ulrich and Rapp, Michael A. and Tschorn, Mira}, title = {The associations of positive and negative valence systems, cognitive systems and social processes on disease severity in anxiety and depressive disorders}, series = {Frontiers in psychiatry}, volume = {14}, journal = {Frontiers in psychiatry}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-0640}, doi = {10.3389/fpsyt.2023.1161097}, pages = {10}, year = {2023}, abstract = {Background Anxiety and depressive disorders share common features of mood dysfunctions. This has stimulated interest in transdiagnostic dimensional research as proposed by the Research Domain Criteria (RDoC) approach by the National Institute of Mental Health (NIMH) aiming to improve the understanding of underlying disease mechanisms. The purpose of this study was to investigate the processing of RDoC domains in relation to disease severity in order to identify latent disorder-specific as well as transdiagnostic indicators of disease severity in patients with anxiety and depressive disorders. Methods Within the German research network for mental disorders, 895 participants (n = 476 female, n = 602 anxiety disorder, n = 257 depressive disorder) were recruited for the Phenotypic, Diagnostic and Clinical Domain Assessment Network Germany (PD-CAN) and included in this cross-sectional study. We performed incremental regression models to investigate the association of four RDoC domains on disease severity in patients with affective disorders: Positive (PVS) and Negative Valance System (NVS), Cognitive Systems (CS) and Social Processes (SP). Results The results confirmed a transdiagnostic relationship for all four domains, as we found significant main effects on disease severity within domain-specific models (PVS: \& beta; = -0.35; NVS: \& beta; = 0.39; CS: \& beta; = -0.12; SP: \& beta; = -0.32). We also found three significant interaction effects with main diagnosis showing a disease-specific association. Limitations The cross-sectional study design prevents causal conclusions. Further limitations include possible outliers and heteroskedasticity in all regression models which we appropriately controlled for. Conclusion Our key results show that symptom burden in anxiety and depressive disorders is associated with latent RDoC indicators in transdiagnostic and disease-specific ways.}, language = {en} } @misc{SonkajaerviRoggeDemuraetal.2004, author = {Sonkaj{\"a}rvi, Hanna and Rogge, J{\"o}rg and Demura, Shin and Fichte, Robby and Alk{\"a}mper, Urte Christine and Tischer, Anuschka and Wollschl{\"a}ger, Thomas and Prass, Reiner and Helmedach, Andreas and Kubetzky, Thomas and Mehrkens, Heidi and Kater, Thomas and Sawilla, Jan Marco and Schneider, Dorit and Uebersch{\"a}r, Ellen and Angelow, J{\"u}rgen and Muth, J{\"o}rg and Lang, Heinrich and Kroll, Stefan and Kroener, Bernhard R. and Pr{\"o}ve, Ralf and Hollberg, Cecilie}, title = {Milit{\"a}r und Gesellschaft in der Fr{\"u}hen Neuzeit}, volume = {8}, number = {1}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, organization = {Arbeitskreis Milit{\"a}r und Gesellschaft in der Fr{\"u}hen Neuzeit e.V. (Hrsg.)}, issn = {1617-9722}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-6765}, year = {2004}, abstract = {Aus dem Inhalt dieser Ausgabe: BEITR{\"A}GE: Hanna Sonkaj{\"a}rvi: Soldaten als Fremde in Straßburg im 18. Jahrhundert, J{\"o}rg Rogge: Das Kriegswesen im sp{\"a}ten Mittelalter und seine Erforschung: neuere englische und deutsche Arbeiten zu Krieg, Staat und Gesellschaft, PROJEKTE: Shin Demura: Allso hiebe der innere krieg schon an, der vil Erger dann der e{\"u}ssere war : die Stadt als Zufluchtsort f{\"u}r Fl{\"u}chtlinge : Erfahrungsformen des Dreißigj{\"a}hrigen Krieges in der Reichsstadt Ulm und ihrer Region, Robby Fichte: Zur Entwicklungsgeschichte des {\"o}ffentlich-rechtlichen Vertrages anhand der Begr{\"u}ndung des Milit{\"a}rdienstverh{\"a}ltnisses 1650-1914, Urte Christine Allk{\"a}mper: Die Braut des Soldaten : symbolische Kommunikation mit der Waffe von der Fr{\"u}hen Neuzeit bis zur Gegenwart, Anuschka Tischer: Offizielle Kriegsbegr{\"u}ndungen in der fr{\"u}hen Neuzeit - Funktionen, Formen, Inhalte, Thomas Wollschl{\"a}ger: Die Military Revolution und der deutsche Territorialstaat unter besonderer Ber{\"u}cksichtigung Brandenburg-Preußens und Sachsens : Determinanten der Staatskonsolidierung im europ{\"a}ischen Kontext 1670-1740, BERICHTE: Reiner Prass: Tagungsbericht Gewalt in der Fr{\"u}hen Neuzeit : 5. Tagung der Arbeitsgemeinschaft Fr{\"u}he Neuzeit vom 18. bis 20. September 2003 an der Freien Universit{\"a}t Berlin, Andreas Helmedach, Thomas Kubetzky, Heidi Mehrkens: Tilly ist nur eine Chiffre, die es aufzul{\"o}sen gilt ... - Jahrestagung des Arbeitskreises Milit{\"a}rgeschichte: Soldat und Gesellschaft : Biographien und Selbstzeugnisse in der Milit{\"a}rgeschichte 10.-11. Oktober 2003, Thomas Kater: Bericht {\"u}ber die Jahrestagung des Arbeitskreises Historische Friedensforschung : Der Friede ist keine leere Idee ... - Bilder und Vorstellungen vom Frieden im langen 19. Jahrhundert, 31.10. bis 2.11.2003, Stiftung Adam von Trott, Imshausen, Jan Marco Sawilla: Religion und Krieg - Bericht {\"u}ber die Hamburger Gespr{\"a}che zur Geschichtswissenschaft (V III.) WS 2003/ 2004, Dorit Schneider: Kriegsbegr{\"u}ndungen in der Geschichte. Strategien der Legitimierung und Legalisierung milit{\"a}rischer Gewalt - 30.-31.01.2004, Deutscher Bundestag, Berlin, REZENSIONEN: Ellen Uebersch{\"a}r: Das Strafgericht Gottes : Kriegserfahrungen und Religion im Heiligen R{\"o}mischen Reich Deutscher Nation im Zeitalter des Dreißigj{\"a}hrigen Krieges, hrsg. von Matthias Asche und Anton Schindling, M{\"u}nster 2001, J{\"u}rgen Angelow: Jutta Nowosadtko: Krieg, Gewalt und Ordnung : Einf{\"u}hrung in die Milit{\"a}rgeschichte, T{\"u}bingen 2002, J{\"o}rg Muth: John A. Lynn: Battle - A History of Combat and Culture from Ancient Greece to Modern Amerika, Boulder 2003, Heinrich Lang: Del Treppo, Mario (H g.): Condottieri e uomini d arme nell Italia del Rinascimento. Acura e con un saggio introduttivo di Mario Del Treppo, Napoli 2001, Stefan Kroll: J{\"o}rg Muth, Flucht aus dem milit{\"a}rischen Alltag : Ursachen und individuelle Auspr{\"a}gung der Desertion in der Armee Friedrichs des Großen. Mit besonderer Ber{\"u}cksichtigung der Infanterie-Regimenter der Potsdamer Garnison, Freiburg i. Br. 2003, ANK{\"U}NDIGUNGEN: Bernhard R. Kroener, Ralf Pr{\"o}ve: Tempi passati! Der Arbeitskreis Milit{\"a}r und Gesellschaft in der Fr{\"u}hen Neuzeit : ein Zwischenbericht nach einem Jahrzehnt, Mitgliederversammlung 2004, AMG-Tagung 2007, Cecilie Hollberg: Glaube \& Macht : Sachsen im Europa der Reformationszeit ; die 2. S{\"a}chsische Landesausstellung ; die Schlacht bei M{\"u}hlberg : Ausgang und Folgen}, subject = {Milit{\"a}r / Geschichte}, language = {de} } @article{SchneiderKohlSauteretal.2012, author = {Schneider, Tobias and Kohl, Benjamin and Sauter, Tilman and Kratz, Karl and Lendlein, Andreas and Ertel, Wolfgang and Schulze-Tanzil, Gundula}, title = {Influence of fiber orientation in electrospun polymer scaffolds on viability, adhesion and differentiation of articular chondrocytes}, series = {Clinical hemorheology and microcirculation : blood flow and vessels}, volume = {52}, journal = {Clinical hemorheology and microcirculation : blood flow and vessels}, number = {2-4}, publisher = {IOS Press}, address = {Amsterdam}, issn = {1386-0291}, doi = {10.3233/CH-2012-1608}, pages = {325 -- 336}, year = {2012}, abstract = {Degradable polymers with a tailorable degradation rate might be promising candidate materials for biomaterial-based cartilage repair. In view of the poor intrinsic healing capability of cartilage, implantation of autologous chondrocytes seeded on a biocompatible slow degrading polymer might be an encouraging approach to improve cartilage repair in the future. This study was undertaken to test if the fiber orientation (random versus aligned) of two different degradable polymers and a polymer intended for long term applications could influence primary articular chondrocytes growth and ultrastructure. A degradable copoly(ether) esterurethane (PDC) was synthesized via co-condensation of poly(p-dioxanone) diol and poly(epsilon-caprolactone) diol using an aliphatic diisocyanate as linker. Poly(p-dioxanone) (PPDO) was applied as commercially available degradable polymer, while polyetherimide (PEI) was chosen as biomaterial enabling surface functionalization. The fibrous scaffolds of PDC and PPDO were obtained by electrospinning using 1,1,1,3,3,3 hexafluoro-2-propanol (HFP), while for PEI dimethyl acetamide (DMAc) was applied as solvent. Primary porcine articular chondrocytes were seeded at different cell densities on the fibrous polymer scaffolds and analyzed for viability (fluorescein diacetate/ethidiumbromide staining), for type II collagen synthesis (immunolabelling), ultrastructure and orientation on the fibers (SEM: scanning electron microscopy). Vital chondrocytes adhered on all electrospun scaffolds irrespective of random and aligned topologies. In addition, the chondrocytes produced the cartilage-specific type II collagen on all tested polymer topologies suggesting their differentiated functions. SEM revealed an almost flattened chondrocytes shape on scaffolds with random fiber orientation: whereby chondrocytes growth remained mainly restricted to the scaffold surface. On aligned fibers the chondrocytes exhibited a more spindle-shaped morphology with rougher cell surfaces but only a minority of the cells aligned according to the fibers. As a next step the reduction of the fiber diameter of electrospun scaffolds should be addressed as an important parameter to mimic cartilage ECM structure.}, language = {en} } @article{LaquaiMuellerSchneideretal.2020, author = {Laquai, Rene and M{\"u}ller, Bernd R. and Schneider, Judith Ann and Kupsch, Andreas and Bruno, Giovanni}, title = {Using SXRR to probe the nature of discontinuities in SLM additive manufactured inconel 718 specimens}, series = {Metallurgical and Materials Transactions A}, volume = {51}, journal = {Metallurgical and Materials Transactions A}, number = {8}, publisher = {Springer}, address = {New York}, issn = {1073-5623}, doi = {10.1007/s11661-020-05847-5}, pages = {4146 -- 4157}, year = {2020}, abstract = {The utilization of additive manufacturing (AM) to fabricate robust structural components relies on understanding the nature of internal anomalies or discontinuities, which can compromise the structural integrity. While some discontinuities in AM microstructures stem from similar mechanisms as observed in more traditional processes such as casting, others are unique to the AM process. Discontinuities in AM are challenging to detect, due to their submicron size and orientation dependency. Toward the goal of improving structural integrity, minimizing discontinuities in an AM build requires an understanding of the mechanisms of formation to mitigate their occurrence. This study utilizes various techniques to evaluate the shape, size, nature and distribution of discontinuities in AM Inconel 718, in a non-hot isostatic pressed (HIPed) as-built, non-HIPed and direct age, and HIPed with two step age samples. Non-destructive synchrotron radiation refraction and transmission radiography (SXRR) provides additional information beyond that obtained with destructive optical microscopy. SXRR was able to distinguish between voids, cracks and lack of melt in, due to its sensitivity to the orientation of the discontinuity.}, language = {en} } @article{EspeRailaHenzeetal.2013, author = {Espe, Katharina M. and Raila, Jens and Henze, Andrea and Blouin, Katja and Schneider, Andreas and Schmiedeke, Daniel and Krane, Vera and Pilz, Stefan and Schweigert, Florian J. and Hocher, Berthold and Wanner, Christoph and Drechsler, Christiane}, title = {Low plasma alpha-tocopherol concentrations and adverse clinical outcomes in diabetic hemodialysis patients}, series = {Clinical journal of the American Society of Nephrology}, volume = {8}, journal = {Clinical journal of the American Society of Nephrology}, number = {3}, publisher = {American Society of Nephrology}, address = {Washington}, organization = {German Diabet \& Dialysis Study Inv}, issn = {1555-9041}, doi = {10.2215/CJN.04880511}, pages = {452 -- 458}, year = {2013}, abstract = {Background and objectives Trials with the antioxidant vitamin E have failed to show benefit in the general population. Considering the different causes of death in ESRD, this study investigated the association between plasma concentrations of alpha-tocopherol and specific clinical outcomes in diabetic hemodialysis patients. Design, settings, participants, \& measurements In 1046 diabetic hemodialysis patients (participants of the German Diabetes and Dialysis Study), alpha-tocopherol was measured in plasma by reversed-phase HPLC. By Cox regression analyses, hazard ratios were determined for prespecified end points according to baseline plasma alpha-tocopherol levels: sudden death (n=134), myocardial infarction (n=172), stroke (n=89), combined cardiovascular events (n=398), fatal infection (n=107), and all-cause mortality (n=508). Results Patients had a mean age of 66 8 years, and mean plasma alpha-tocopherol level was 22.8+/-9.6 mu mol/L. Levels of alpha-tocopherol were highly correlated to triglycerides (r=0.63, P<0.001). Patients in the lowest alpha-tocopherol quartile had (in unadjusted analyses) a 79\% higher risk of stroke and a 31\% higher risk of all-cause mortality compared with patients in the highest quartile. The associations were attenuated after adjustment for confounders (hazard ratio(stroke)=1.56, 95\% confidence interval=0.75-3.25; hazard ratio(mortality)=1.22, 95\% confidence interval=0.89-1.69, respectively). There was no association between alpha-tocopherol and myocardial infarction, sudden death, or infectious death. Conclusions Plasma alpha-tocopherol concentrations were not independently associated with cardiovascular outcomes, infectious deaths, or all-cause mortality in diabetic hemodialysis patients. The lack of association can partly be explained by a confounding influence of malnutrition, which should be considered in the planning of trials to reduce cardiovascular risk in dialysis patients.}, language = {en} } @article{OttoSchraderSteigeretal.1997, author = {Otto, Andreas H. and Schrader, Sigurd and Steiger, Th. and Schneider, M.}, title = {Gas phase deprotonation energies of Sulfuric Acid, Perchloric Acid, Chlorsulfuric Acid and Fluorosulfuric Acid}, year = {1997}, language = {en} } @article{WawrzinekZiomkowskaHeuvelingetal.2013, author = {Wawrzinek, Robert and Ziomkowska, Joanna and Heuveling, Johanna and Mertens, Monique and Herrmann, Andreas and Schneider, Erwin and Wessig, Pablo}, title = {DBD Dyes as Fluorescence Lifetime Probes to Study Conformational Changes in Proteins}, series = {CHEMISTRY-A EUROPEAN JOURNAL}, volume = {19}, journal = {CHEMISTRY-A EUROPEAN JOURNAL}, number = {51}, publisher = {WILEY-V C H VERLAG GMBH}, address = {WEINHEIM}, issn = {0947-6539}, doi = {10.1002/chem.201302368}, pages = {17349 -- 17357}, year = {2013}, abstract = {Previously, [1,3]dioxolo[4,5-f][1,3]benzodioxole (DBD)-based fluorophores used as highly sensitive fluorescence lifetime probes reporting on their microenvironmental polarity have been described. Now, a new generation of DBD dyes has been developed. Although they are still sensitive to polarity, in contrast to the former DBD dyes, they have extraordinary spectroscopic properties even in aqueous surroundings. They are characterized by long fluorescence lifetimes (10-20ns), large Stokes shifts (approximate to 100nm), high photostabilities, and high quantum yields (>0.56). Here, the spectroscopic properties and synthesis of functionalized derivatives for labeling biological targets are described. Furthermore, thio-reactive maleimido derivatives of both DBD generations show strong intramolecular fluorescence quenching. This mechanism has been investigated and is found to undergo a photoelectron transfer (PET) process. After reaction with a thiol group, this fluorescence quenching is prevented, indicating successful bonding. Being sensitive to their environmental polarity, these compounds have been used as powerful fluorescence lifetime probes for the investigation of conformational changes in the maltose ATP-binding cassette transporter through fluorescence lifetime spectroscopy. The differing tendencies of the fluorescence lifetime change for both DBD dye generations promote their combination as a powerful toolkit for studying microenvironments in proteins.}, language = {en} } @article{AnsellStenoienGrundmannetal.2010, author = {Ansell, Stephen W. and Stenoien, Hans K. and Grundmann, Michael and Schneider, Harald and Hemp, Andreas and Bauer, N. and Russell, S. J. and Vogel, Johannes C.}, title = {Population structure and historical biogeography of European Arabidopsis lyrata}, issn = {0018-067X}, doi = {10.1038/Hdy.2010.10}, year = {2010}, abstract = {Understanding the natural history of model organisms is important for the effective use of their genomic resourses. Arabidopsis lyrata has emerged as a useful plant for studying ecological and evolutionary genetics, based on its extensive natural variation, sequenced genome and close relationship to A. thaliana. We studied genetic diversity across the entire range of European Arabidopsis lyrata ssp. petraea, in order to explore how population history has influenced population structure. We sampled multiple populations from each region, using nuclear and chloroplast genome markers, and combined population genetic and phylogeographic approaches. Within-population diversity is substantial for nuclear allozyme markers (mean P = 0.610, A(e) = 1.580, H-e = 0.277) and significantly partitioned among populations (F- ST = 0.271). The Northern populations have modestly increased inbreeding (F-IS = 0.163 verses F-IS = 0.093), but retain comparable diversity to central European populations. Bottlenecks are common among central and northern Europe populations, indicating recent demographic history as a dominant factor in structuring the European diversity. Although the genetic structure was detected at all geographic scales, two clear differentiated units covering northern and central European areas (F-CT = 0.155) were identified by Bayesian analysis and supported by regional pairwise F-CT calculations. A highly similar geographic pattern was observed from the distribution of chloroplast haplotypes, with the dominant northern haplotypes absent from central Europe. We conclude A. l. petraea's cold-tolerance and preference for disturbed habitats enabled glacial survival between the alpine and Nordic glaciers in central Europe and an additional cryptic refugium. While German populations are probable peri-glacial leftovers, Eastern Austrian populations have diversity patterns possibly compatible with longer-term survival.}, language = {en} } @article{ZirafiKimStaendkeretal.2015, author = {Zirafi, Onofrio and Kim, Kyeong-Ae and St{\"a}ndker, Ludger and Mohr, Katharina B. and Sauter, Daniel and Heigele, Anke and Kluge, Silvia F. and Wiercinska, Eliza and Chudziak, Doreen and Richter, Rudolf and M{\"o}pps, Barbara and Gierschik, Peter and Vas, Virag and Geiger, Hartmut and Lamla, Markus and Weil, Tanja and Burster, Timo and Zgraja, Andreas and Daubeuf, Francois and Frossard, Nelly and Hachet-Haas, Muriel and Heunisch, Fabian and Reichetzeder, Christoph and Galzi, Jean-Luc and Perez-Castells, Javier and Canales-Mayordomo, Angeles and Jimenez-Barbero, Jesus and Gimenez-Gallego, Guillermo and Schneider, Marion and Shorter, James and Telenti, Amalio and Hocher, Berthold and Forssmann, Wolf-Georg and Bonig, Halvard and Kirchhoff, Frank and M{\"u}nch, Jan}, title = {Discovery and Characterization of an Endogenous CXCR4 Antagonist}, series = {Cell reports}, volume = {11}, journal = {Cell reports}, number = {5}, publisher = {Cell Press}, address = {Cambridge}, issn = {2211-1247}, doi = {10.1016/j.celrep.2015.03.061}, pages = {737 -- 747}, year = {2015}, abstract = {CXCL12-CXCR4 signaling controls multiple physiological processes and its dysregulation is associated with cancers and inflammatory diseases. To discover as-yet-unknown endogenous ligands of CXCR4, we screened a blood-derived peptide library for inhibitors of CXCR4-tropic HIV-1 strains. This approach identified a 16 amino acid fragment of serum albumin as an effective and highly specific CXCR4 antagonist. The endogenous peptide, termed EPI-X4, is evolutionarily conserved and generated from the highly abundant albumin precursor by pH-regulated proteases. EPI-X4 forms an unusual lasso-like structure and antagonizes CXCL12-induced tumor cell migration, mobilizes stem cells, and suppresses inflammatory responses in mice. Furthermore, the peptide is abundant in the urine of patients with inflammatory kidney diseases and may serve as a biomarker. Our results identify EPI-X4 as a key regulator of CXCR4 signaling and introduce proteolysis of an abundant precursor protein as an alternative concept for chemokine receptor regulation.}, language = {en} } @article{SzymanskiToenniesBecheretal.2012, author = {Szymanski, Kolja V. and T{\"o}nnies, Mario and Becher, Anne and Fatykhova, Diana and N'Guessan, Philippe D. and Gutbier, Birgitt and Klauschen, Frederick and Neusch{\"a}fer-Rube, Frank and Schneider, Paul and R{\"u}ckert, Jens and Neudecker, Jens and Bauer, Torsten T. and Dalhoff, Klaus and Droemann, Daniel and Gruber, Achim D. and Kershaw, Olivia and Temmesfeld-Wollbrueck, Bettina and Suttorp, Norbert and Hippenstiel, Stefan and Hocke, Andreas C.}, title = {Streptococcus pneumoniae-induced regulation of cyclooxygenase-2 in human lung tissue}, series = {The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology}, volume = {40}, journal = {The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology}, number = {6}, publisher = {European Respiratory Society}, address = {Sheffield}, issn = {0903-1936}, doi = {10.1183/09031936.00186911}, pages = {1458 -- 1467}, year = {2012}, abstract = {The majority of cases of community-acquired pneumonia are caused by Streptococcus pneumoniae and most studies on pneumococcal host interaction are based on cell culture or animal experiments. Thus, little is known about infections in human lung tissue. Cyclooxygenase-2 and its metabolites play an important regulatory role in lung inflammation. Therefore, we established a pneumococcal infection model on human lung tissue demonstrating mitogen-activated protein kinase (MAPK)-dependent induction of cyclooxygenase-2 and its related metabolites. In addition to alveolar macrophages and the vascular endothelium, cyclooxygenase-2 was upregulated in alveolar type II but not type I epithelial cells, which was confirmed in lungs of patients suffering from acute pneumonia. Moreover, we demonstrated the expression profile of all four E prostanoid receptors at the mRNA level and showed functionality of the E prostanoid(4) receptor by cyclic adenosine monophosphate production. Additionally, in comparison to previous studies, cyclooxygenase-2/prostaglandin E-2 related pro- and anti-inflammatory mediator regulation was partly confirmed in human lung tissue after pneumococcal infection. Overall, cell type-specific and MAPK-dependent cyclooxygenase-2 expression and prostaglandin E-2 formation in human lung tissue may play an important role in the early phase of pneumococcal infections.}, language = {en} } @article{HeuvelingFrochauxZiomkowskaetal.2014, author = {Heuveling, Johanna and Frochaux, Violette and Ziomkowska, Joanna and Wawrzinek, Robert and Wessig, Pablo and Herrmann, Andreas and Schneider, Erwin}, title = {Conformational changes of the bacterial type I ATP-binding cassette importer HisQMP(2) at distinct steps of the catalytic cycle}, series = {Biochimica et biophysica acta : Biomembranes}, volume = {1838}, journal = {Biochimica et biophysica acta : Biomembranes}, number = {1}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0005-2736}, doi = {10.1016/j.bbamem.2013.08.024}, pages = {106 -- 116}, year = {2014}, abstract = {Prokaryotic solute binding protein-dependent ATP-binding cassette import systems are divided into type land type II and mechanistic differences in the transport process going along with this classification are under intensive investigation. Little is known about the conformational dynamics during the catalytic cycle especially concerning the transmembrane domains. The type I transporter for positively charged amino acids from Salmonella enterica serovar Typhimurium (1A0-Hi5QMP2) was studied by limited proteolysis in detergent solution in the absence and presence of co-factors including ATP, ADP, LAO/arginine, and Mg2+ ions. Stable peptide fragments could be obtained and differentially susceptible cleavage sites were determined by mass spectrometry as Lys-258 in the nucleotide-binding subunit, HisP, and Arg-217/Arg-218 in the transmembrane subunit, HisQ In contrast, transmembrane subunit HisM was gradually degraded but no stable fragment could be detected. HisP and HisQ were equally resistant under pre- and post-hydrolysis conditions in the presence of arginine-loaded solute-binding protein LAO and ATP/ADP. Some protection was also observed with LAO/arginine alone, thus reflecting binding to the transporter in the apo-state and transmembrane signaling. Comparable digestion patterns were obtained with the transporter reconstituted into proteoliposomes and nanodiscs. Fluorescence lifetime spectroscopy confirmed the change of HisQ(R218) to a more apolar microenvironment upon ATP binding and hydrolysis. Limited proteolysis was subsequently used as a tool to study the consequences of mutations on the transport cycle. Together, our data suggest similar conformational changes during the transport cycle as described for the maltose ABC transporter of Escherichia coli, despite distinct structural differences between both systems.}, language = {en} } @article{BlumeSchneiderGuentner2021, author = {Blume, Theresa and Schneider, Lisa and G{\"u}ntner, Andreas}, title = {Comparative analysis of throughfall observations in six different forest stands}, series = {Hydrological processes}, volume = {36}, journal = {Hydrological processes}, number = {3}, publisher = {Wiley}, address = {Hoboken}, issn = {0885-6087}, doi = {10.1002/hyp.14461}, pages = {21}, year = {2021}, abstract = {Throughfall, that is, the fraction of rainfall that passes through the forest canopy, is strongly influenced by rainfall and forest stand characteristics which are in turn both subject to seasonal dynamics. Disentangling the complex interplay of these controls is challenging, and only possible with long-term monitoring and a large number of throughfall events measured in parallel at different forest stands. We therefore based our analysis on 346 rainfall events across six different forest stands at the long-term terrestrial environmental observatory TERENO Northeast Germany. These forest stands included pure stands of beech, pine and young pine, and mixed stands of oak-beech, pine-beech and pine-oak-beech. Throughfall was overall relatively low, with 54-68\% of incident rainfall in summer. Based on the large number of events it was possible to not only investigate mean or cumulative throughfall but also its statistical distribution. The distributions of throughfall fractions show distinct differences between the three types of forest stands (deciduous, mixed and pine). The distributions of the deciduous stands have a pronounced peak at low throughfall fractions and a secondary peak at high fractions in summer, as well as a pronounced peak at higher throughfall fractions in winter. Interestingly, the mixed stands behave like deciduous stands in summer and like pine stands in winter: their summer distributions are similar to the deciduous stands but the winter peak at high throughfall fractions is much less pronounced. The seasonal comparison further revealed that the wooden components and the leaves behaved differently in their throughfall response to incident rainfall, especially at higher rainfall intensities. These results are of interest for estimating forest water budgets and in the context of hydrological and land surface modelling where poor simulation of throughfall would adversely impact estimates of evaporative recycling and water availability for vegetation and runoff.}, language = {en} } @misc{SchneiderGuenterTaubert2018, author = {Schneider, Matthias and G{\"u}nter, Christina and Taubert, Andreas}, title = {Co-deposition of a hydrogel/calcium phosphate hybrid layer on 3D printed poly(lactic acid) scaffolds via dip coating}, series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, number = {1057}, issn = {1866-8372}, doi = {10.25932/publishup-47442}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-474427}, pages = {21}, year = {2018}, abstract = {The article describes the surface modification of 3D printed poly(lactic acid) (PLA) scaffolds with calcium phosphate (CP)/gelatin and CP/chitosan hybrid coating layers. The presence of gelatin or chitosan significantly enhances CP co-deposition and adhesion of the mineral layer on the PLA scaffolds. The hydrogel/CP coating layers are fairly thick and the mineral is a mixture of brushite, octacalcium phosphate, and hydroxyapatite. Mineral formation is uniform throughout the printed architectures and all steps (printing, hydrogel deposition, and mineralization) are in principle amenable to automatization. Overall, the process reported here therefore has a high application potential for the controlled synthesis of biomimetic coatings on polymeric biomaterials.}, language = {en} } @article{SchneiderGuenterTaubert2018, author = {Schneider, Matthias and G{\"u}nter, Christina and Taubert, Andreas}, title = {Co-deposition of a hydrogel/calcium phosphate hybrid layer on 3D printed poly(lactic acid) scaffolds via dip coating}, series = {Polymers}, volume = {10}, journal = {Polymers}, number = {3}, publisher = {MDPI}, address = {Basel}, issn = {2073-4360}, doi = {10.3390/polym10030275}, pages = {19}, year = {2018}, abstract = {The article describes the surface modification of 3D printed poly(lactic acid) (PLA) scaffolds with calcium phosphate (CP)/gelatin and CP/chitosan hybrid coating layers. The presence of gelatin or chitosan significantly enhances CP co-deposition and adhesion of the mineral layer on the PLA scaffolds. The hydrogel/CP coating layers are fairly thick and the mineral is a mixture of brushite, octacalcium phosphate, and hydroxyapatite. Mineral formation is uniform throughout the printed architectures and all steps (printing, hydrogel deposition, and mineralization) are in principle amenable to automatization. Overall, the process reported here therefore has a high application potential for the controlled synthesis of biomimetic coatings on polymeric biomaterials.}, language = {en} } @book{MientusKlempinNowaketal.2023, author = {Mientus, Lukas and Klempin, Christiane and Nowak, Anna and Wyss, Corinne and Aufschnaiter, Claudia von and Faix, Ann-Christin and te Poel, Kathrin and Wahbe, Nadia and Pieper, Martin and H{\"o}ller, Katharina and Kallenbach, Lea and F{\"o}rster, Magdalena and Redecker, Anke and Dick, Mirjam and Holle, J{\"o}rg and Schneider, Edina and Rehfeldt, Daniel and Brauns, Sarah and Abels, Simone and Ferencik-Lehmkuhl, Daria and Fr{\"a}nkel, Silvia and Frohn, Julia and Liebsch, Ann-Catherine and Pech, Detlef and Schreier, Pascal and Jessen, Moiken and Großmann, Uta and Skintey, Lesya and Voerkel, Paul and Vaz Ferreira, Mergenfel A. and Zimmermann, Jan-Simon and Buddeberg, Magdalena and Henke, Vanessa and Hornberg, Sabine and V{\"o}lschow, Yvette and Warrelmann, Julia-Nadine and Malek, Jennifer and Tinnefeld, Anja and Schmidt, Peggy and Bauer, Tobias and J{\"a}nisch, Christopher and Spitzer, Lisa and Franken, Nadine and Degeling, Maria and Preisfeld, Angelika and Meier, Jana and K{\"u}th, Simon and Scholl, Daniel and Vogelsang, Christoph and Watson, Christina and Weißbach, Anna and Kulgemeyer, Christoph and Oetken, Mandy and Gorski, Sebastian and Kubsch, Marcus and Sorge, Stefan and Wulff, Peter and Fellenz, Carolin D. and Schnell, Susanne and Larisch, Cathleen and Kaiser, Franz and Knott, Christina and Reimer, Stefanie and Stegm{\"u}ller, Nathalie and Boukray{\^a}a Trabelsi, Kathrin and Schißlbauer, Franziska and Lemberger, Lukas and Barth, Ulrike and Wiehl, Angelika and Rogge, Tim and B{\"o}hnke, Anja and Dietz, Dennis and Großmann, Leroy and Wienmeister, Annett and Zoppke, Till and Jiang, Lisa and Gr{\"u}nbauer, Stephanie and Ostersehlt, D{\"o}rte and Peukert, Sophia and Sch{\"a}fer, Christoph and L{\"o}big, Anna and Br{\"o}ll, Leena and Brandt, Birgit and Breuer, Meike and Dausend, Henriette and Krelle, Michael and Andersen, Gesine and Falke, Sascha and Kindermann-G{\"u}zel, Kristin and K{\"o}rner, Katrina and Lottermoser, Lisa-Marie and P{\"u}gner, Kati and Sonnenburg, Nadine and Akarsu, Selim and Rechl, Friederike and Gadinger, Laureen and Heinze, Lena and Wittmann, Eveline and Franke, Manuela and Lachmund, Anne-Marie and B{\"o}ttger, Julia and Hannover, Bettina and Behrendt, Renata and Conty, Valentina and Grundmann, Stephanie and Ghassemi, Novid and Opitz, Ben and Br{\"a}mer, Martin and Gasparjan, David and Sambanis, Michaela and K{\"o}ster, Hilde and L{\"u}cke, Martin and Nordmeier, Volkhard and Schaal, Sonja and Haberbosch, Maximilian and Meissner, Maren and Schaal, Steffen and Br{\"u}chner, Melanie and Riehle, Tamara and Leopold, Bengta Marie and Gerlach, Susanne and Rau-Patschke, Sarah and Skorsetz, Nina and Weber, Nadine and Damk{\"o}hler, Jens and Elsholz, Markus and Trefzger, Thomas and Lewek, Tobias and Borowski, Andreas}, title = {Reflexion in der Lehrkr{\"a}ftebildung}, series = {Potsdamer Beitr{\"a}ge f{\"u}r Lehrkr{\"a}ftebildung und Bildungsforschung}, journal = {Potsdamer Beitr{\"a}ge f{\"u}r Lehrkr{\"a}ftebildung und Bildungsforschung}, number = {4}, editor = {Mientus, Lukas and Klempin, Christiane and Nowak, Anna}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-566-8}, issn = {2626-3556}, doi = {10.25932/publishup-59171}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-591717}, publisher = {Universit{\"a}t Potsdam}, pages = {452}, year = {2023}, abstract = {Reflexion ist eine Schl{\"u}sselkategorie f{\"u}r die professionelle Entwicklung von Lehrkr{\"a}ften, welche als Ausbildungsziel in den Bildungsstandards f{\"u}r die Lehrkr{\"a}ftebildung verankert ist. Eine Verstetigung universit{\"a}r gepr{\"a}gter Forschung und Modellierung in der praxisnahen Anwendung im schulischen Kontext bietet Potentiale nachhaltiger Professionalisierung. Die St{\"a}rkung reflexionsbezogener Kompetenzen durch Empirie und Anwendung scheint eine phasen{\"u}bergreifende Herausforderung der Lehrkr{\"a}ftebildung zu sein, die es zu bew{\"a}ltigen gilt. Ziele des Tagungsbandes Reflexion in der Lehrkr{\"a}ftebildung sind eine theoretische Sch{\"a}rfung des Konzeptes „Reflexive Professionalisierung" und der Austausch {\"u}ber Fragen der Einbettung wirksamer reflexionsbezogener Lerngelegenheiten in die Lehrkr{\"a}ftebildung. Forschende und Lehrende der‚ drei Phasen (Studium, Referendariat sowie Fort- und Weiterbildung) der Lehrkr{\"a}ftebildung stellen Lehrkonzepte und Forschungsprojekte zum Thema Reflexion in der Lehrkr{\"a}ftebildung vor und diskutieren diese. Gemeinsam mit Teilnehmenden aller Phasen und von verschiedenen Standorten der Lehrkr{\"a}ftebildung werden zuk{\"u}nftige Herausforderungen identifiziert und L{\"o}sungsans{\"a}tze herausgearbeitet.}, language = {de} } @article{DerakhshaniKurzJaptoketal.2019, author = {Derakhshani, Shaghayegh and Kurz, Andreas and Japtok, Lukasz and Schumacher, Fabian and Pilgram, Lisa and Steinke, Maria and Kleuser, Burkhard and Sauer, Markus and Schneider-Schaulies, Sibylle and Avota, Elita}, title = {Measles Virus Infection Fosters Dendritic Cell Motility in a 3D Environment to Enhance Transmission to Target Cells in the Respiratory Epithelium}, series = {Frontiers in immunology}, volume = {10}, journal = {Frontiers in immunology}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-3224}, doi = {10.3389/fimmu.2019.01294}, pages = {14}, year = {2019}, abstract = {Transmission of measles virus (MV) from dendritic to airway epithelial cells is considered as crucial to viral spread late in infection. Therefore, pathways and effectors governing this process are promising targets for intervention. To identify these, we established a 3D respiratory tract model where MV transmission by infected dendritic cells (DCs) relied on the presence of nectin-4 on H358 lung epithelial cells. Access to recipient cells is an important prerequisite for transmission, and we therefore analyzed migration of MV-exposed DC cultures within the model. Surprisingly, enhanced motility toward the epithelial layer was observed for MV-infected DCs as compared to their uninfected siblings. This occurred independently of factors released from H358 cells indicating that MV infection triggered cytoskeletal remodeling associated with DC polarization enforced velocity. Accordingly, the latter was also observed for MV-infected DCs in collagen matrices and was particularly sensitive to ROCK inhibition indicating infected DCs preferentially employed the amoeboid migration mode. This was also implicated by loss of podosomes and reduced filopodial activity both of which were retained in MV-exposed uninfected DCs. Evidently, sphingosine kinase (SphK) and sphingosine-1-phosphate (S1P) as produced in response to virus-infection in DCs contributed to enhanced velocity because this was abrogated upon inhibition of sphingosine kinase activity. These findings indicate that MV infection promotes a push-and-squeeze fast amoeboid migration mode via the SphK/S1P system characterized by loss of filopodia and podosome dissolution. Consequently, this enables rapid trafficking of virus toward epithelial cells during viral exit.}, language = {en} } @article{CastroFossatiHubrigetal.2015, author = {Castro, Norberto and Fossati, Luca and Hubrig, Swetlana and Simon D{\´i}az, Sergio and Schoeller, Markus and Ilyin, Ilya and Carrol, Thorsten A. and Langer, Norbert and Morel, Thierry and Schneider, Fabian R. N. and Przybilla, Norbert and Herrero, Artemio and de Koter, Alex and Oskinova, Lida and Reisenegger, Andreas and Sana, Hugues}, title = {B fields in OB stars (BOB) Detection of a strong magnetic field in the O9.7 V star HD 54879}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {581}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, organization = {BOB Collaboration}, issn = {1432-0746}, doi = {10.1051/0004-6361/201425354}, pages = {14}, year = {2015}, abstract = {The number of magnetic stars detected among massive stars is small; nevertheless, the role played by the magnetic field in stellar evolution cannot be disregarded. Links between line profile variability, enhancements/depletions of surface chemical abundances, and magnetic fields have been identified for low-mass B-stars, but for the O-type domain this is almost unexplored. Based on FORS 2 and HARPS spectropolarimetric data, we present the first detection of a magnetic field in HD54879, a single slowly rotating O9.7 V star. Using two independent and different techniques we obtained the firm detection of a surface average longitudinal magnetic field with a maximum amplitude of about 600 G, in modulus. A quantitative spectroscopic analysis of the star with the stellar atmosphere code FASTWIND results in an effective temperature and a surface gravity of 33 000 +/- 1000K and 4.0 +/- 0.1 dex. The abundances of carbon, nitrogen, oxygen, silicon, and magnesium are found to be slightly lower than solar, but compatible within the errors. We investigate line-profile variability in HD54879 by complementing our spectra with spectroscopic data from other recent OB-star surveys. The photospheric lines remain constant in shape between 2009 and 2014, although H alpha shows a variable emission. The H alpha emission is too strong for a standard O9.7 V and is probably linked to the magnetic field and the presence of circumstellar material. Its normal chemical composition and the absence of photospheric line profile variations make HD54879 the most strongly magnetic, non-variable single O-star detected to date.}, language = {en} } @article{FossatiCastroMoreletal.2015, author = {Fossati, Luca and Castro, Norberto and Morel, Thierry and Langer, Norbert and Briquet, Maryline and Carroll, Thorsten Anthony and Hubrig, Swetlana and Nieva, Maria-Fernanda and Oskinova, Lida and Przybilla, Norbert and Schneider, Fabian R. N. and Schoeller, Magnus and Simon D{\´i}az, Sergio and Ilyin, Ilya and de Koter, Alex and Reisenegger, Andreas and Sana, Hugues}, title = {B fields in OB stars (BOB): on the detection of weak magnetic fields in the two early B-type stars beta CMa and epsilon CMa Possible lack of a "magnetic desert" in massive stars}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {574}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, organization = {BOB Collaboration}, issn = {0004-6361}, doi = {10.1051/0004-6361/201424986}, pages = {15}, year = {2015}, abstract = {Only a small fraction of massive stars seem to host a measurable structured magnetic field, whose origin is still unknown and whose implications for stellar evolution still need to be assessed. Within the context of the "B fields in OB stars (BOB)" collaboration, we used the HARPSpol spectropolarimeter to observe the early B-type stars beta CMa (HD 44743; B1 II/III) and epsilon CMa (HD 52089; B1.5II) in December 2013 and April 2014. For both stars, we consistently detected the signature of a weak (<30 G in absolute value) longitudinal magnetic field, approximately constant with time. We determined the physical parameters of both stars and characterise their X-ray spectrum. For the beta Cep star beta CMa, our mode identification analysis led to determining a rotation period of 13.6 +/- 1.2 days and of an inclination angle of the rotation axis of 57.6 +/- 1.7 degrees, with respect to the line of sight. On the basis of these measurements and assuming a dipolar field geometry, we derived a best fitting obliquity of about 22 degrees and a dipolar magnetic field strength (B-d) of about 100 G (60 < B-d < 230 G within the 1 sigma level), below what is typically found for other magnetic massive stars. This conclusion is strengthened further by considerations of the star's X-ray spectrum. For epsilon CMa we could only determine a lower limit on the dipolar magnetic field strength of 13 G. For this star, we determine that the rotation period ranges between 1.3 and 24 days. Our results imply that both stars are expected to have a dynamical magnetosphere, so the magnetic field is not able to support a circumstellar disk. We also conclude that both stars are most likely core hydrogen burning and that they have spent more than 2/3 of their main sequence lifetime. A histogram of the distribution of the dipolar magnetic field strength for the magnetic massive stars known to date does not show the magnetic field "desert" observed instead for intermediate-mass stars. The biases involved in the detection of (weak) magnetic fields in massive stars with the currently available instrumentation and techniques imply that weak fields might be more common than currently observed. Our results show that, if present, even relatively weak magnetic fields are detectable in massive stars and that more observational effort is probably still needed to properly access the magnetic field incidence.}, language = {en} } @misc{IvenHansenAndersetal.2020, author = {Iven, Claudia and Hansen, Bernd and Anders, Kristina and Starke, Andreas and Richardt, Kirsten and Pr{\"u}ß, Holger and El Meskioui, Martina and Haase, Tobias and Mahlberg, Lea and Wiehe, Lea and de Beer, Carola and Niepelt Karampamapa, Rebekka and Hofmann, Andrea and Stadie, Nicole and Hanne, Sandra and Thomson, Jenny and Sch{\"a}fer, Blanca and Huttenlauch, Clara and Wartenburger, Isabell and Weiland, Katharina and Wirsam, Anke and Hartung, Julia and Wahl, Michael and Unger, Julia and Buschmann, Anke and Seefeld, Martin and Bethge, Anita and Fieder, Nora and Rahman, Rasha Abdel and Nousair, Iman and Klassert, Annegret and Wellmann, Caroline and Verbree, Rahel and van Rij, Jacolien and Sprenger, Simone and M{\"a}hl, Anna Luisa and Schneider, Kathleen and Kutz, Anne and Kaps, Hella and Frank, Ulrike and Brekeller, Sophie and Ryll, Katja}, title = {Spektrum Patholinguistik Band 12. Schwerpunktthema: Weg(e) mit dem Stottern: Therapie und Selbsthilfe f{\"u}r Kinder und Erwachsene}, series = {Spektrum Patholinguistik}, journal = {Spektrum Patholinguistik}, number = {12}, editor = {Breitenstein, Sarah and Burmester, Juliane and Yetim, {\"O}zlem and Fritzsche, Tom}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-479-1}, issn = {1866-9085}, doi = {10.25932/publishup-43700}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-437002}, pages = {viii, 257}, year = {2020}, abstract = {Das 12. Herbsttreffen Patholinguistik mit dem Schwerpunktthema »Weg(e) mit dem Stottern: Therapie und Selbsthilfe f{\"u}r Kinder und Erwachsene« fand am 24.11.2018 in Potsdam statt. Das Herbsttreffen wird seit 2007 j{\"a}hrlich vom Verband f{\"u}r Patholinguistik e.V. (vpl) durchgef{\"u}hrt. Der vorliegende Tagungsband beinhaltet die Vortr{\"a}ge zum Schwerpunktthema sowie Beitr{\"a}ge der Posterpr{\"a}sentationen zu weiteren Themen aus der sprachtherapeutischen Forschung und Praxis.}, language = {de} } @book{FuhrmannGoertzKlagesetal.2020, author = {Fuhrmann, Michaela and Goertz, Stefanie and Klages, Benjamin and Last, Dominique and Strickroth, Sven and Schubarth, Wilfried and Mauermeister, Sylvi and Schulze-Reichelt, Friederike and Erdmann, Melinda and Dreyer, Martin and Konarski, Michael and T{\"a}gener, Judith and Lucke, Ulrike and Hafer, J{\"o}rg and Hartmann, Niklas and Nguyen, Thi To-Uyen and Wittkowski, Ariane and Prickett, David James and Degen, Andreas and Rost, Sophia and Kiy, Alexander and Wagner, Nelli and G{\"o}del, Corinna and Klinnert, Anne and Babbe, Caroline and Schneider, Marie and Hille, Kerstin}, title = {Lehre und Lernen entwickeln - Eine Frage der Gestaltung von {\"U}berg{\"a}ngen}, series = {Potsdamer Beitr{\"a}ge zur Hochschulforschung}, journal = {Potsdamer Beitr{\"a}ge zur Hochschulforschung}, number = {6}, editor = {Goertz, Stefanie and Klages, Benjamin and Last, Dominique and Strickroth, Sven}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-498-2}, issn = {2192-1075}, doi = {10.25932/publishup-47681}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-476815}, publisher = {Universit{\"a}t Potsdam}, pages = {336}, year = {2020}, abstract = {An der Universit{\"a}t Potsdam wurden im Rahmen des Qualit{\"a}tspakt Lehre-Projekts „Qualit{\"a}t etablieren in Lehre und Lernen (QueLL)" Maßnahmen f{\"u}r eine Verbesserung der Studienbedingungen und eine Weiterentwicklung der Lehre und des Lernens durchgef{\"u}hrt. Die w{\"a}hrend der neunj{\"a}hrigen Projektlaufzeit thematisierten Fragestellungen, erarbeiteten L{\"o}sungsans{\"a}tze und entsprechenden Erfahrungen werden im vorliegenden Sammelband in Form von wissenschaftlichen Auseinandersetzungen und Werkstattberichten dargestellt und diskutiert. Die Beitr{\"a}ge spiegeln in ihrer thematischen Vielfalt unterschiedliche universit{\"a}re {\"U}bergangsphasen wider, wie in diesem Fall den {\"U}bergang in die Hochschule, {\"U}berg{\"a}nge innerhalb der Hochschule (im Kontext der Organisationsentwicklung, der Weiterbildung akademischer Statusgruppen oder der Entwicklung einer digitalen Lehr-Lernkultur) und schließlich den {\"U}bergang in die Berufspraxis. Denn w{\"a}hrend der Projektlaufzeit hat sich gezeigt, dass die Gestaltung von Lehre und Lernen letztlich immer eine Gestaltung solcher {\"U}berg{\"a}nge ist: sowohl zwischen den innerinstitutionellen Ebenen und Bereichen als auch zwischen Akteur/innen der Hochschule und schließlich ebenso innerhalb des Student Life Cycle. Weiterhin wird anhand der Beitr{\"a}ge deutlich, dass die Entwicklung von Lehre und Studium nicht als isolierte Aufgabe verstanden werden kann, sondern in die Strukturen und Prozesse der Universit{\"a}t hineinwirken und Formen der Zusammenarbeit etablieren sollte, die es braucht, um Projekte nachhaltig zu gestalten. Ziel dieses Bandes ist es, zur Diskussion {\"u}ber Gelingensbedingungen einer nachhaltigen Entwicklung von Lehre und Lernen beizutragen. Damit richtet er sich an Akteur/innen aus der Hochschulleitung, an Lehrende und Forschende sowie Mitarbeitende des Third Space.}, language = {de} } @article{SchneiderFritzschePuciulMalinowskaetal.2020, author = {Schneider, Matthias and Fritzsche, Nora and Puciul-Malinowska, Agnieszka and Baliś, Andrzej and Mostafa, Amr and Bald, Ilko and Zapotoczny, Szczepan and Taubert, Andreas}, title = {Surface etching of 3D printed poly(lactic acid) with NaOH}, series = {Polymers}, volume = {12}, journal = {Polymers}, number = {8}, publisher = {MDPI}, address = {Basel}, issn = {2073-4360}, doi = {10.3390/polym12081711}, pages = {16}, year = {2020}, abstract = {The article describes a systematic investigation of the effects of an aqueous NaOH treatment of 3D printed poly(lactic acid) (PLA) scaffolds for surface activation. The PLA surface undergoes several morphology changes and after an initial surface roughening, the surface becomes smoother again before the material dissolves. Erosion rates and surface morphologies can be controlled by the treatment. At the same time, the bulk mechanical properties of the treated materials remain unaltered. This indicates that NaOH treatment of 3D printed PLA scaffolds is a simple, yet viable strategy for surface activation without compromising the mechanical stability of PLA scaffolds.}, language = {en} } @misc{SchneiderFritzschePuciulMalinowskaetal.2020, author = {Schneider, Matthias and Fritzsche, Nora and Puciul-Malinowska, Agnieszka and Balis, Andrzej and Mostafa, Amr and Bald, Ilko and Zapotoczny, Szczepan and Taubert, Andreas}, title = {Surface etching of 3D printed poly(lactic acid) with NaOH: a systematic approach}, series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, number = {8}, issn = {1866-8372}, doi = {10.25932/publishup-52508}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-525088}, pages = {18}, year = {2020}, abstract = {The article describes a systematic investigation of the effects of an aqueous NaOH treatment of 3D printed poly(lactic acid) (PLA) scaffolds for surface activation. The PLA surface undergoes several morphology changes and after an initial surface roughening, the surface becomes smoother again before the material dissolves. Erosion rates and surface morphologies can be controlled by the treatment. At the same time, the bulk mechanical properties of the treated materials remain unaltered. This indicates that NaOH treatment of 3D printed PLA scaffolds is a simple, yet viable strategy for surface activation without compromising the mechanical stability of PLA scaffolds.}, language = {en} } @article{SchneiderFritzschePuciulMalinowskaetal.2020, author = {Schneider, Matthias and Fritzsche, Nora and Puciul-Malinowska, Agnieszka and Balis, Andrzej and Mostafa, Amr and Bald, Ilko and Zapotoczny, Szczepan and Taubert, Andreas}, title = {Surface etching of 3D printed poly(lactic acid) with NaOH: a systematic approach}, series = {Polymers}, volume = {12}, journal = {Polymers}, number = {8}, publisher = {MDPI}, address = {Basel}, pages = {16}, year = {2020}, abstract = {The article describes a systematic investigation of the effects of an aqueous NaOH treatment of 3D printed poly(lactic acid) (PLA) scaffolds for surface activation. The PLA surface undergoes several morphology changes and after an initial surface roughening, the surface becomes smoother again before the material dissolves. Erosion rates and surface morphologies can be controlled by the treatment. At the same time, the bulk mechanical properties of the treated materials remain unaltered. This indicates that NaOH treatment of 3D printed PLA scaffolds is a simple, yet viable strategy for surface activation without compromising the mechanical stability of PLA scaffolds.}, language = {en} } @article{SchaffenrothCasewellSchneideretal.2020, author = {Schaffenroth, Veronika and Casewell, Sarah L. and Schneider, D. and Kilkenny, David and Geier, Stephan and Heber, Ulrich and Irrgang, Andreas and Przybilla, Norbert and Marsh, Thomas R. and Littlefair, Stuart P. and Dhillon, Vik S.}, title = {A quantitative in-depth analysis of the prototype sdB plus BD system SDSS J08205+0008 revisited in the Gaia era}, series = {Monthly notices of the Royal Astronomical Society}, volume = {501}, journal = {Monthly notices of the Royal Astronomical Society}, number = {3}, publisher = {Oxford Univ. Press}, address = {Oxford}, issn = {0035-8711}, doi = {10.1093/mnras/staa3661}, pages = {3847 -- 3870}, year = {2020}, abstract = {Subdwarf B stars are core-helium-burning stars located on the extreme horizontal branch (EHB). Extensive mass loss on the red giant branch is necessary to form them. It has been proposed that substellar companions could lead to the required mass loss when they are engulfed in the envelope of the red giant star. J08205+0008 was the first example of a hot subdwarf star with a close, substellar companion candidate to be found. Here, we perform an in-depth re-analysis of this important system with much higher quality data allowing additional analysis methods. From the higher resolution spectra obtained with ESO-VLT/XSHOOTER, we derive the chemical abundances of the hot subdwarf as well as its rotational velocity. Using the Gaia parallax and a fit to the spectral energy distribution in the secondary eclipse, tight constraints to the radius of the hot subdwarf are derived. From a long-term photometric campaign, we detected a significant period decrease of -3.2(8) x 10(-12) dd(-1). This can be explained by the non-synchronized hot subdwarf star being spun up by tidal interactions forcing it to become synchronized. From the rate of period decrease we could derive the synchronization time-scale to be 4 Myr, much smaller than the lifetime on EHB. By combining all different methods, we could constrain the hot subdwarf to a mass of 0.39-0.50 M-circle dot and a radius of R-sdB = 0.194 +/- 0.008 R-circle dot, and the companion to 0.061-0.071 M-circle dot with a radius of R-comp = 0.092 +/- 0.005 R-circle dot, below the hydrogen-burning limit. We therefore confirm that the companion is most likely a massive brown dwarf.}, language = {en} }