@article{BornhorstXiaNakajimaetal.2019, author = {Bornhorst, Dorothee and Xia, Peng and Nakajima, Hiroyuki and Dingare, Chaitanya and Herzog, Wiebke and Lecaudey, Virginie and Mochizuki, Naoki and Heisenberg, Carl-Philipp and Yelon, Deborah and Abdelilah-Seyfried, Salim}, title = {Biomechanical signaling within the developing zebrafish heart attunes endocardial growth to myocardial chamber dimensions}, series = {Nature Communications}, volume = {10}, journal = {Nature Communications}, publisher = {Nature Publ. Group}, address = {London}, issn = {2041-1723}, doi = {10.1038/s41467-019-12068-x}, pages = {10}, year = {2019}, abstract = {Intra-organ communication guides morphogenetic processes that are essential for an organ to carry out complex physiological functions. In the heart, the growth of the myocardium is tightly coupled to that of the endocardium, a specialized endothelial tissue that lines its interior. Several molecular pathways have been implicated in the communication between these tissues including secreted factors, components of the extracellular matrix, or proteins involved in cell-cell communication. Yet, it is unknown how the growth of the endocardium is coordinated with that of the myocardium. Here, we show that an increased expansion of the myocardial atrial chamber volume generates higher junctional forces within endocardial cells. This leads to biomechanical signaling involving VE-cadherin, triggering nuclear localization of the Hippo pathway transcriptional regulator Yap1 and endocardial proliferation. Our work suggests that the growth of the endocardium results from myocardial chamber volume expansion and ends when the tension on the tissue is relaxed.}, language = {en} } @article{WangWangWangetal.2016, author = {Wang, Hao and Wang, Xue-jiang and Wang, Wei-shi and Yan, Xiang-bo and Xia, Peng and Chen, Jie and Zhao, Jian-fu}, title = {Modeling and optimization of struvite recovery from wastewater and reusing for heavy metals immobilization in contaminated soil}, series = {Journal of chemical technology \& biotechnology}, volume = {91}, journal = {Journal of chemical technology \& biotechnology}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {0268-2575}, doi = {10.1002/jctb.4931}, pages = {3045 -- 3052}, year = {2016}, abstract = {BACKROUND: Few studies have been carried out to connect nutrients recovery from wastewater and heavy metals immobilization in contaminated soil. To achieve the goal, ammonia nitrogen (AN) and phosphorus (P) were recovered from rare-earth wastewater by using the formation of struvite, which was used as the amendment with plant ash for copper, lead and chromium immobilization. RESULTS: AN removal efficiency and residual P reached 95.32 +/- 0.73\% and 6.14 +/- 1.72mgL(-1) under optimal conditions: pH= 9.0, n(Mg): n(N): n(P)= 1.2: 1: 1.1, which were obtained using response surface methodology (RSM). The minimum available concentrations of Cu, Pb and Cr (CPC) separately reduced to 320.82 mg kg(-1), 190.77 mg kg(-1) and 121.46 mg kg(-1) with increasing immobilization time at the mass ratio of phosphate precipitate (PP)/plant ash (PA) of 1: 3. Humic acid (HA) and fulvic acid (FA) were beneficial to immobilize Cu, both of which showed no effect or even a negative effect on Pb and Cr immobilization.}, language = {en} } @article{ZhangCaoXuetal.2022, author = {Zhang, Naimeng and Cao, Xianyong and Xu, Qinghai and Huang, Xiaozhong and Herzschuh, Ulrike and Shen, Zhongwei and Peng, Wei and Liu, Sisi and Wu, Duo and Wang, Jian and Xia, Huan and Zhang, Dongju and Chen, Fahu}, title = {Vegetation change and human-environment interactions in the Qinghai Lake Basin, northeastern Tibetan Plateau, since the last deglaciation}, series = {Catena}, volume = {210}, journal = {Catena}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0341-8162}, doi = {10.1016/j.catena.2021.105892}, pages = {14}, year = {2022}, abstract = {The nature of the interaction between prehistoric humans and their environment, especially the vegetation, has long been of interest. The Qinghai Lake Basin in North China is well-suited to exploring the interactions between prehistoric humans and vegetation in the Tibetan Plateau, because of the comparatively dense distribution of archaeological sites and the ecologically fragile environment. Previous pollen studies of Qinghai Lake have enabled a detailed reconstruction of the regional vegetation, but they have provided relatively little information on vegetation change within the Qinghai Lake watershed. To address the issue we conducted a pollen-based vegetation reconstruction for an archaeological site (YWY), located on the southern shore of Qinghai Lake. We used high temporal-resolution pollen records from the YWY site and from Qinghai Lake, spanning the interval since the last deglaciation (15.3 kyr BP to the present) to quantitatively reconstruct changes in the local and regional vegetation using Landscape Reconstruction Algorithm models. The results show that, since the late glacial, spruce forest grew at high altitudes in the surrounding mountains, while the lakeshore environment was occupied mainly by shrub-steppe. From the lateglacial to the middle Holocene, coniferous woodland began to expand downslope and reached the YWY site at 7.1 kyr BP. The living environment of the local small groups of Paleolithic-Epipaleolithic humans (during 15.3-13.1 kyr BP and 9-6.4 kyr BP) changed from shrub-steppe to coniferous forest-steppe. The pollen record shows no evidence of pronounced changes in the vegetation community corresponding to human activity. However, based on a comparison of the local and regional vegetation reconstructions, low values of biodiversity and a significant increase in two indicators of vegetation degradation, Chenopodiaceae and Rosaceae, suggest that prehistoric hunters-gatherers likely disturbed the local vegetation during 9.0-6.4 kyr BP. Our findings are a preliminary attempt to study human-environment interactions at Paleolithic-Epipaleolithic sites in the region, and they contribute to ongoing environmental archaeology research in the Tibetan Plateau.}, language = {en} }