@article{RiemerRiemerKruegeretal.2021,
  author    = {Riemer, Nastja and Riemer, Martin and Kr{\"u}ger, Mandy and Clarkson, Guy J. and Shipman, Michael and Schmidt, Bernd},
  title     = {Synthesis of arylidene-beta-lactams via exo-selective Matsuda-Heck arylation of methylene-beta-lactams},
  series = {The journal of organic chemistry : JOC},
  volume    = {86},
  journal   = {The journal of organic chemistry : JOC},
  number    = {13},
  publisher = {American Chemical Society},
  address   = {Washington},
  issn      = {0022-3263},
  doi       = {10.1021/acs.joc.1c00638},
  pages     = {8786 -- 8796},
  year      = {2021},
  abstract  = {exo-Methylene-beta-lactams were synthesized in two steps from commercially available 3-bromo-2-(bromomethyl)-propionic acid and reacted with arene diazonium salts in a Heck-type arylation in the presence of catalytic amounts of Pd(OAc)(2) under ligand-free conditions. The products, arylidene-beta-lactams, were obtained in high yields as single isomers. The beta-hydride elimination step of the Pd-catalyzed coupling reaction proceeds with high exo-regioselectivity and E-stereoselectivity. With aryl iodides, triflates, or bromides, the coupling products were isolated only in low yields, due to extensive decomposition of the starting material at elevated temperatures. This underlines that arene diazonium salts can be superior arylating reagents in Heck-type reactions and yield coupling products in synthetically useful yields and selectivities when conventional conditions fail.},
  language  = {en}
}
@article{RiemerShipmanWessigetal.2019,
  author    = {Riemer, Nastja and Shipman, Michael and Wessig, Pablo and Schmidt, Bernd},
  title     = {Iterative arylation of itaconimides with diazonium salts through electrophilic palladium catalysis},
  series = {The journal of organic chemistry},
  volume    = {84},
  journal   = {The journal of organic chemistry},
  number    = {9},
  publisher = {American Chemical Society},
  address   = {Washington},
  issn      = {0022-3263},
  doi       = {10.1021/acs.joc.9b00627},
  pages     = {5732 -- 5746},
  year      = {2019},
  abstract  = {N-Arylitaconimides, accessible from maleic anhydride, anilines, and paraformaldehyde, react with arene diazonium salts in Pd-catalyzed Matsuda-Heck arylation to the pharmacologically relevant E-configured 3-arylmethylidene pyrrolidine-2,5-diones (also known as arylmethylidene succinimides) through exo-selective beta-H-elimination. The coupling proceeds at ambient temperature with the simple and easy-to-handle precatalyst Pd-II-acetate under ligandand base-free conditions. Notable features are high isolated yields, regio- and stereoselectivities, and short reaction times. In a comparative investigation, aryl iodides, bromides, and triflates were shown to be inferior coupling reagents in this reaction. The 3-arylmethylidene pyrrolidine-2,5-diones undergo second Matsuda-Heck coupling, which proceeds via endo-selective beta-H-elimination to give diarylmethyl-substituted maleimides as coupling products. These products can also be accessed in one flask by sequential addition of different arene diazonium salts to the starting itaconimide. The potential of 3-arylmethylidene succinimides as photoswitches was tested. Upon irradiation of the E-isomer at 300 nm, partial isomerization to the Z-isomer (E/Z = 65:35 in the photostationary state) was observed. The isomerization was found to be nearly completely reversible by irradiating the mixture at 400 nm.},
  language  = {en}
}
@article{RiemerCoswigShipmanetal.2018,
  author    = {Riemer, Nastja and Coswig, Christin and Shipman, Michael and Schmidt, Bernd},
  title     = {Palladium-catalyzed cross-coupling of arenediazonium salts with organoindium or organobismuth reagents},
  series = {Synlett : accounts and rapid communications in synthetic organic chemistry},
  volume    = {29},
  journal   = {Synlett : accounts and rapid communications in synthetic organic chemistry},
  number    = {18},
  publisher = {Georg Thieme Verlag KG},
  address   = {Stuttgart},
  issn      = {0936-5214},
  doi       = {10.1055/s-0037-1611001},
  pages     = {2427 -- 2431},
  year      = {2018},
  abstract  = {Arylindium and isolated triarylbismuth compounds generated in situ react as nucleophiles with arenediazonium salts in palladium-catalyzed cross-coupling reactions to give substituted biphenyls.},
  language  = {en}
}
@article{SchmidtElizarovRiemeretal.2015,
  author    = {Schmidt, Bernd and Elizarov, Nelli and Riemer, Nastja and H{\"o}lter, Frank},
  title     = {Acetamidoarenediazonium Salts: Opportunities for Multiple Arene Functionalization},
  series = {European journal of organic chemistry},
  journal   = {European journal of organic chemistry},
  number    = {26},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1434-193X},
  doi       = {10.1002/ejoc.201500795},
  pages     = {5826 -- 5841},
  year      = {2015},
  abstract  = {Unlike their ortho counterparts, meta- and para-acetamidoanilines can be converted into the corresponding acetamidoarenediazonium salts. These offer various opportunities for multiple Pd-catalyzed arene functionalization reactions, such as Matsuda-Heck-, Suzuki-Miyaura- or Fujiwara-Moritani couplings.},
  language  = {en}
}
@phdthesis{Riemer2018,
  author    = {Riemer, Nastja},
  title     = {Diazoniumsalze f{\"u}r die Synthese von Pflanzenschutzmitteln},
  school      = {Universit{\"a}t Potsdam},
  pages     = {187},
  year      = {2018},
  language  = {de}
}