@article{LondershausenTurbergBieseleretal.1996, author = {Londershausen, M. and Turberg, Andreas and Bieseler, Barbara and Lennarz, M. and Peter, Martin G.}, title = {Characterization and Inhibitor Studies of Chitinases from Parasitic Blowfly (Lucilia cuprina), Tick (Boophilus micoplus), Intestinale Nematode (Haemonchus contortus), and a Bean (Phaseolus vulgaris)}, year = {1996}, language = {en} } @article{LondershausenTurbergSpindlerBarthetal.1996, author = {Londershausen, M. and Turberg, Andreas and Spindler-Barth, Margarethe and Peter, Martin G.}, title = {Screening Test for Insecticides Interfering with Cuticular Sclerotization}, year = {1996}, language = {en} } @article{Peter1995, author = {Peter, Martin G.}, title = {Applications and environmental aspects of chitin and chitosan}, issn = {0022-233X}, year = {1995}, language = {en} } @article{SchumacherWanderslebPeter1995, author = {Schumacher-Wandersleb, Michael H. M. G. and Peter, Martin G.}, title = {Synthesis of chitobiosyl pyrrolidines}, year = {1995}, language = {en} } @article{AbegazPeter1995, author = {Abegaz, Berhanu M. and Peter, Martin G.}, title = {Emodine and emodinanthrone rhamnoside acetates from fruits of rhamnus prinoides}, issn = {0031-9422}, year = {1995}, language = {en} } @article{Peter1995, author = {Peter, Martin G.}, title = {The Bio-organic chemistry of melanogenesis}, year = {1995}, language = {en} } @article{Peter1995, author = {Peter, Martin G.}, title = {Chemie i Biochemia Zewnetrznego Szkieletu Owadow : (Chemistry and biochemistry of the insect exoskeleton)}, year = {1995}, language = {en} } @article{Peter1995, author = {Peter, Martin G.}, title = {Chemistry and biochemistry of the insect exoskeleton}, year = {1995}, language = {en} } @article{Peter1995, author = {Peter, Martin G.}, title = {Chitin in den Startl{\"o}chern}, issn = {0009-2959}, year = {1995}, language = {de} } @article{PeterMerz1995, author = {Peter, Martin G. and Merz, A.}, title = {Stereoselective benzylic deprotonation in the enzymatic rearrangement of N-acetyldopamine derived o-Quinone to the p-Quinone methide}, issn = {0957-4166}, year = {1995}, language = {en} } @article{LeyPeter1994, author = {Ley, J. P. and Peter, Martin G.}, title = {Synthesis of N-(2-Acetamido-2-deoxy-ß-D-glucopyranosyl)- and of N-(N,N-Diacetylchitobiosyl)-amide of lhistidine}, issn = {0039-7881}, year = {1994}, language = {en} } @article{PeterAndersen1994, author = {Peter, Martin G. and Andersen, S. O.}, title = {The molecular architecture of the insect exoskeleton}, year = {1994}, language = {en} } @article{SchumacherWanderslebPetersenPeter1994, author = {Schumacher-Wandersleb, Michael H. M. G. and Petersen, Stefan and Peter, Martin G.}, title = {Preparation of the N-Acetylglucosaminidase inhibitor 1-Acetamido-1,2,5-tride oxy-2,5-imino-D-glucitol from methyl a-D-Mannopyranoside}, year = {1994}, language = {en} } @article{PeterLeyPetersenetal.1994, author = {Peter, Martin G. and Ley, J. P. and Petersen, Stefan and Londershausen, M. and Schumacher-Wandersleb, Michael H. M. G. and Spindler, Klaus-Dieter and Spindler-Barth, Margarethe and Turberg, Andreas}, title = {Synthesis of chitinase inhibitors}, year = {1994}, language = {en} } @article{KroescheCrescenziHoffbaueretal.1994, author = {Kr{\"o}sche, Christian and Crescenzi, Orlando and Hoffbauer, Wilfried and Jansen, Martin and Napolitano, Alessandra and Prota, Guiseppe and Peter, Martin G.}, title = {Synthesis of dopamines labelled with 13C in the alpha- or beta-side chain positions, and their application for structure studies on melanins by solid state NMR spectroscopy}, year = {1994}, language = {en} } @misc{PeterAndersenHartmannetal.1992, author = {Peter, Martin G. and Andersen, Svend Olav and Hartmann, Rudolf and Miessner, Merle and Roepstorff, Peter}, title = {Catecholamine-protein conjugates : isolation of 4-phenylphenoxazin-2-ones from oxidative coupling of N-acetyldopamine with alipathic amino acids}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-17571}, year = {1992}, abstract = {4-Phenylphenoxazinones were isolated after biomimetic oxidation, using diphenoloxidases of insect cuticle, mushroom tyrosinase, or after autoxidation of N-acetyldopamine (Image ) in the presence of β-alanine, β-alanine methyl ester or N-acetyl-L-lysine. They are formed presumably by addition of 2-aminoalkyl-5-alkylphenols to the o-quinone of biphenyltetrol which, in turn, arises from oxidative coupling of. The structures of present the first examples for the assembly of reasonably stable intermediates in the rather complex process of chemical modifications of aliphatic amino acid residues by o-quinones.}, language = {en} } @misc{AndersenPerterRoepstorff1992, author = {Andersen, Svend Olav and Perter, Martin G. and Roepstorff, Peter}, title = {Cuticle-catalyzed coupling between N-acetylhistidine and N-acetyldopamine}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-16762}, year = {1992}, abstract = {Several types of insect cuticle contain enzymes catalyzing the formation ofof adducts between N-acetyldopamine (NADA) and N-acetylhistidine (NAH). Two such adducts, NAH-NADA-I and NAH NADA-II, have been isolated and their structures determined. In one of the adducts the link connecting the two residues occurs between the I-position (ß-position) in the NADA side chain and the 1-N atom (τ-N) in the imidazole ring of histidine. Diphenoloxidase activity alone is not sufficient for formation of this adduct, whereas extracts containing both diphenoloxidase and o-quinone-p-quinone methide isomerase activities catalyze the coupling reaction. The adduct consists of a mixture of two diastereomers and they are presumably formed by spontaneous reaction between enzymatically produced NADA-p-quinone methide and N-acetylhistidine. The other adduct has been identified as a ring addition product of N-acetylhistidine and NADA. In contrast to the former adduct it can be formed by incubation of the two substrates with mushroom tyrosinase alone. An adduct between N-acetylhistidine and the benzodioxan-type NADA-dimer is produced in vitro, when the N-acetylhistidine-NADA adduct is incubated with NADA and locust cuticle containing a 1,2-dehydro-NADA generating enzyme system. Trimeric NADA-polymerization products of the substituted benzodioxan-type have been obtained from in vivo sclerotized locust cuticle, confirming the ability of cuticle to produce NADA-oligomers. The results indicate that some insect cuticles contain enzymes promoting linkage of oxidized NADA to histidine residues. It is suggested that histidine residues in the cuticular proteins can serve as acceptors for oxidized NADA and that further addition of NADA-residues to the phenolic groups of bound NADA can occur, resulting in formation of protein-linked NADA-oligomers. The coupling reactions identified may be an important step in natural cuticular sclerotization.}, language = {en} } @misc{PeterBoldtNiedersteinetal.1990, author = {Peter, Martin G. and Boldt, Peter C. and Niederstein, Yvonne and Peter-Katalinić, Jasna}, title = {Synthesen von Galactose-Cluster-haltigen Steroid-Derivaten}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-16783}, year = {1990}, abstract = {The synthesis of galactose clusters that are linked to a steroid moiety by a peptide-like spacer unit is described. The galactose cluster is obtained by Koenigs-Knorr glycosylation of TRIS-Gly-Fmoc (2b) under Helferich conditions. Peptide and ester bonds are formed after activation of carboxylic acids as diphenylthiophene dioxide (TDO) esters. 6a is synthesized in a convergent way by coupling of (Ac4Gal)3-TRIS-Gly (3e) with cholesteryl TDO succinate (5b). Coupling of (Ac4Gal)3-TRIS-Gly hydrogen succinate (3f) with Gly-O-Chol (5d) by means of EEDQ yields 6d. Reaction of (Ac4Gal)3-TRIS-Gly-SUCC-O-TDO (3g) with 25-hydroxycholesterol leads in a linear sequence to the oxysterol derivative 6f. Selective cleavage of the acetyl groups from galactose units yields the known compound 6b and the new derivatives 6e and 6g.}, language = {de} } @misc{PeterFoerster1989, author = {Peter, Martin G. and F{\"o}rster, Hans}, title = {On the structure of Eumelanins : identification of constitutional patterns by solid-state NMR spectroscopy}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-17027}, year = {1989}, abstract = {Aus dem Inhalt: Melanins are complex polyphenolic polymers. They are usually formed in nature by enzyme-catalyzed oxidative polymerization of o-diphenols. The deep black eumelanins, derived from Dopa 1 or dopamine 3, are distinguished from the yellow to brown phaeomelanins obtained from Dopa in the presence of cysteine. Characteristic of eumelanins are the indole units, which are formed from catecholamines by intramolecular addition of the amino groups to the oxidatively generated o-quinones. [...]}, language = {en} } @misc{Peter1989, author = {Peter, Martin G.}, title = {Chemische Modifikation von Biopolymeren durch Chinone und Chinonmethide}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-16802}, year = {1989}, abstract = {Chinone und Vorstufen, die oxidativ in Chinone und/oder Chinonmethide umgewandelt werden k{\"o}nnen, sind in der Natur weit verbreitet. Als sekund{\"a}re Naturstoffe wirken sie h{\"a}ufig antibiotisch, cytotoxisch, aber auch pathogen, und eine Reihe von Pflanzen und Tieren benutzt chinoide Substanzen als Abwehrstoffe, oft mit spektakul{\"a}rem Erfolg. Auf makromolekularer Ebene spielen Chinonmethide im Pflanzenreich eine Schl{\"u}sselrolle bei der Biosynthese von Lignin, w{\"a}hrend die Bildung von Melanoproteinen ein Beispiel f{\"u}r Reaktionen von o-Chinonen im Tierreich ist. Bei den Insekten dienen Chinone und Chinonmethide zur Bildung des lebensnotwendigen Exoskeletts. Die Reaktivit{\"a}t von Chinonen in biologischen Systemen hat auch f{\"u}r den Menschen unmittelbare Bedeutung in pharmazeutischer, toxikologischer und technologischer Hinsicht. Den Beispielen in diesem Aufsatz liegt ein gemeinsames Prinzip zugrunde, n{\"a}mlich die chemische Modifikation von Biopolymeren durch Chinone und Chinonmethide. Wie sich besonders bei einer detaillierteren Betrachtung der Reaktionen zeigt, die zur Sklerotisierung der Insektencuticula f{\"u}hren, sind in den letzten Jahren wichtige neue Erkenntnisse hinzugekommen, die vor allem durch die modernen Methoden der Stofftrennung und der Festk{\"o}rper-NMR-Spektroskopie erm{\"o}glicht worden sind.}, language = {de} }