@book{GonzalesDiazKasperRainer1997, author = {Gonz{\´a}les-Diaz, P. F. and Kasper, Uwe and Rainer, Martin}, title = {2-Dimensional dilatonic gravity from multidimensional Einstein gravity}, series = {Preprint / Universit{\"a}t Potsdam, Institut f{\"u}r Mathematik}, volume = {1997, 22}, journal = {Preprint / Universit{\"a}t Potsdam, Institut f{\"u}r Mathematik}, publisher = {Univ.}, address = {Potsdam}, pages = {14 Bl.}, year = {1997}, language = {en} } @article{PeterLeyPetersenetal.1994, author = {Peter, Martin G. and Ley, J. P. and Petersen, Stefan and Londershausen, M. and Schumacher-Wandersleb, Michael H. M. G. and Spindler, Klaus-Dieter and Spindler-Barth, Margarethe and Turberg, Andreas}, title = {Synthesis of chitinase inhibitors}, year = {1994}, language = {en} } @article{LimFriemelMarumetal.2013, author = {Lim, Sze Chern and Friemel, Martin and Marum, Justine E. and Tucker, Elena J. and Bruno, Damien L. and Riley, Lisa G. and Christodoulou, John and Kirk, Edwin P. and Boneh, Avihu and DeGennaro, Christine M. and Springer, Michael and Mootha, Vamsi K. and Rouault, Tracey A. and Leimk{\"u}hler, Silke and Thorburn, David R. and Compton, Alison G.}, title = {Mutations in LYRM4, encoding ironsulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexes}, series = {Human molecular genetics}, volume = {22}, journal = {Human molecular genetics}, number = {22}, publisher = {Oxford Univ. Press}, address = {Oxford}, issn = {0964-6906}, doi = {10.1093/hmg/ddt295}, pages = {4460 -- 4473}, year = {2013}, abstract = {Ironsulfur clusters (ISCs) are important prosthetic groups that define the functions of many proteins. Proteins with ISCs (called ironsulfur or FeS proteins) are present in mitochondria, the cytosol, the endoplasmic reticulum and the nucleus. They participate in various biological pathways including oxidative phosphorylation (OXPHOS), the citric acid cycle, iron homeostasis, heme biosynthesis and DNA repair. Here, we report a homozygous mutation in LYRM4 in two patients with combined OXPHOS deficiency. LYRM4 encodes the ISD11 protein, which forms a complex with, and stabilizes, the sulfur donor NFS1. The homozygous mutation (c.203GT, p.R68L) was identified via massively parallel sequencing of 1000 mitochondrial genes (MitoExome sequencing) in a patient with deficiency of complexes I, II and III in muscle and liver. These three complexes contain ISCs. Sanger sequencing identified the same mutation in his similarly affected cousin, who had a more severe phenotype and died while a neonate. Complex IV was also deficient in her skeletal muscle. Several other FeS proteins were also affected in both patients, including the aconitases and ferrochelatase. Mutant ISD11 only partially complemented for an ISD11 deletion in yeast. Our in vitro studies showed that the l-cysteine desulfurase activity of NFS1 was barely present when co-expressed with mutant ISD11. Our findings are consistent with a defect in the early step of ISC assembly affecting a broad variety of FeS proteins. The differences in biochemical and clinical features between the two patients may relate to limited availability of cysteine in the newborn period and suggest a potential approach to therapy.}, language = {en} } @article{EstherGroeneveldEnrightetal.2008, author = {Esther, Alexandra and Groeneveld, J{\"u}rgen and Enright, Neal J. and Miller, Ben P. and Lamont, Byron B. and Perry, George L. W. and Schurr, Frank Martin and Jeltsch, Florian}, title = {Assessing the importance of seed immigration on coexistence of plant functional types in a species-rich ecosystem}, issn = {0304-3800}, doi = {10.1016/j.ecolmodel.2008.01.014}, year = {2008}, abstract = {Modelling and empirical studies have shown that input from the regional seed pool is essential to maintain local species diversity. However, most of these studies have concentrated on simplified, if not neutral, model systems, and focus on a limited subset of species or on aggregated measures of diversity only (e.g., species richness or Shannon diversity). Thus they ignore more complex species interactions and important differences between species. To gain a better understanding of how seed immigration affects community structure at the local scale in real communities we conducted computer simulation experiments based on plant functional types (PFTs) for a species-rich, fire-prone Mediterranean-type shrubland in Western Australia. We developed a spatially explicit simulation model to explore the community dynamics of 38 PFTs, defined by seven traits - regeneration mode, seed production, seed size, maximum crown diameter, drought tolerance, dispersal mode and seed bank type - representing 78 woody species. Model parameterisation is based on published and unpublished data on the population dynamics of shrub species collected over 18 years. Simulation experiments are based on two contrasting seed immigration scenarios: (1) the 'equal seed input number' scenario, where the number of immigrant seeds is the same for all PFTs, and (2) the 'equal seed input mass' scenario, where the cumulative mass of migrating seeds is the same for all PFTs. Both scenarios were systematically tested and compared for different overall seed input values. Without immigration the local community drifts towards a state with only 13 coexisting PFTs. With increasing immigration rates in terms of overall mass of seeds the simulated number of coexisting PFTs and Shannon diversity quickly approaches values observed in the field. The equal seed mass scenario resulted in a more diverse community than did the seed number scenario. The model successfully approximates the frequency distributions (relative densities) of all individual plant traits except seed size for scenarios associated with equal seed input mass and high immigration rate. However, no scenario satisfactorily approximated the frequency distribution for all traits in combination. Our results show that regional seed input can explain the more aggregated measures of local community structure, and some, but not all, aspects of community composition. This points to the possible importance of other (untested) processes and traits (e.g., dispersal vectors) operating at the local scale. Our modelling framework can readily allow new factors to be systematically investigated, which is a major advantage compared to previous simulation studies, as it allows us to find structurally realistic models, which can address questions pertinent to ecological theory and to conservation management.}, language = {en} } @article{TsukamotoHaebelValencaetal.2008, author = {Tsukamoto, Junko and Haebel, Sophie and Valenca, Gustavo P. and Peter, Martin G. and FRanco, Telma T.}, title = {Enzymatic direct synthesis of acrylic acid esters of mono- and disaccharides}, issn = {0268-2575}, year = {2008}, abstract = {Background: There is an increased need to replace materials derived from fossil sources by renewables. Sugar- cane derived carbohydrates are very abundant in Brazil and are the cheapest sugars available in the market, with more than 400 million tons of sugarcane processed in the year 2007. The objective of this work was to study the prepn. of sugar acrylates from free sugars and free acrylic acid, thus avoiding the previous prepn. of protected sugar derivs., such as glycosides, or activated acrylates, such as vinyl acrylate. Results: Lipase catalyzed esterification of three mono- and two disaccharides with acrylic acid, in the presence or absence of mol. sieves was investigated. The reactions were monitored by high-performance liq. chromatog. (HPLC) and the products were analyzed by matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry. The main products are mono- and diacrylates, while higher esters are formed as minor products. The highest conversion to sugar acrylates was obsd. for the D-glucose and D- fructose, followed by D-xylose and D-maltose. Mol. sieves had no pronounced effect on the conversion. Conclusions: A feasible method is described to produce and to characterize sugar acrylates, including those contg. more than two acrylate groups. The process for prodn. of these higher esters could potentially be optimized further to produce mols. for crosslinking in acrylate polymn. and other applications. The direct enzymic esterification of free carbohydrates with acrylic acid is unprecedented. [on SciFinder (R)].}, language = {en} } @article{MiedemaBeyeKoenneckeetal.2014, author = {Miedema, P. S. and Beye, Martin and Koennecke, R. and Schiwietz, G. and F{\"o}hlisch, Alexander}, title = {The angular- and crystal-momentum transfer through electron-phonon coupling in silicon and silicon-carbide: similarities and differences}, series = {New journal of physics : the open-access journal for physics}, volume = {16}, journal = {New journal of physics : the open-access journal for physics}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {1367-2630}, doi = {10.1088/1367-2630/16/9/093056}, pages = {17}, year = {2014}, abstract = {Electron-phonon scattering has been studied for silicon carbide (6H-SiC) with resonant inelastic x-ray scattering at the silicon 2p edge. The observed electron-phonon scattering yields a crystal momentum transfer rate per average phonon in 6H-SiC of 1.8 fs(-1) while it is 0.2 fs(-1) in crystalline silicon. The angular momentum transfer rate per average phonon for 6H-SiC is 0.1 fs(-1), which is much higher than 0.0035 fs(-1) obtained for crystalline silicon in a previous study. The higher electron-phonon scattering rates in 6H-SiC are a result of the larger electron localization at the silicon atoms in 6H-SiC as compared to crystalline silicon. While delocalized valence electrons can screen effectively (part of) the electron-phonon interaction, this effect is suppressed for 6H-SiC in comparison to crystalline silicon. Smaller contributions to the difference in electron-phonon scattering rates between 6H-SiC and silicon arise from the lower atomic mass of carbon versus silicon and the difference in local symmetry.}, language = {en} } @article{PereiraNascimentoMagalhaesetal.2014, author = {Pereira, Fernanda S. and Nascimento, Heliara D. L. and Magalhaes, Alvicler and Peter, Martin G. and Bataglion, Giovana Anceski and Eberlin, Marcos N. and Gonzalez, Eduardo R. P.}, title = {ESI(+)-MS and GC-MS study of the hydrolysis of N-azobenzyl derivatives of chitosan}, series = {Molecules}, volume = {19}, journal = {Molecules}, number = {11}, publisher = {MDPI}, address = {Basel}, issn = {1420-3049}, doi = {10.3390/molecules191117604}, pages = {17604 -- 17618}, year = {2014}, abstract = {New N-p-chloro-, N-p-bromo-, and N-p-nitrophenylazobenzylchitosan derivatives, as well as the corresponding azophenyl and azophenyl-p-sulfonic acids, were synthesized by coupling N-benzylvchitosan with aryl diazonium salts. The synthesized molecules were analyzed by UV-Vis, FT-IR, H-1-NMR and N-15-NMR spectroscopy. The capacity of copper chelation by these materials was studied by AAS. Chitosan and the derivatives were subjected to hydrolysis and the products were analyzed by ESI(+)-MS and GC-MS, confirming the formation of N-benzyl chitosan. Furthermore, the MS results indicate that a nucleophilic aromatic substitution (SnAr) reaction occurs under hydrolysis conditions, yielding chloroaniline from N-p-bromo-, and N-p-nitrophenylazo-benzylchitosan as well as bromoaniline from N-p-chloro-, and N-p-nitrophenylazobenzyl-chitosan.}, language = {en} } @article{AdamBovend'EerdtvanDoorenetal.2012, author = {Adam, Jos J. and Bovend'Eerdt, Thamar J. H. and van Dooren, Fleur E. P. and Fischer, Martin H. and Pratt, Jay}, title = {The closer the better hand proximity dynamically affects letter recognition accuracy}, series = {Attention, perception, \& psychophysics : AP\&P ; a journal of the Psychonomic Society, Inc.}, volume = {74}, journal = {Attention, perception, \& psychophysics : AP\&P ; a journal of the Psychonomic Society, Inc.}, number = {7}, publisher = {Springer}, address = {New York}, issn = {1943-3921}, doi = {10.3758/s13414-012-0339-3}, pages = {1533 -- 1538}, year = {2012}, abstract = {A growing literature has suggested that processing of visual information presented near the hands is facilitated. In this study, we investigated whether the near-hands superiority effect also occurs with the hands moving. In two experiments, participants performed a cyclical bimanual movement task requiring concurrent visual identification of briefly presented letters. For both the static and dynamic hand conditions, the results showed improved letter recognition performance with the hands closer to the stimuli. The finding that the encoding advantage for near-hand stimuli also occurred with the hands moving suggests that the effect is regulated in real time, in accordance with the concept of a bimodal neural system that dynamically updates hand position in external space.}, language = {en} } @article{TeriacaAndrettaAuchereetal.2012, author = {Teriaca, Luca and Andretta, Vincenzo and Auchere, Frederic and Brown, Charles M. and Buchlin, Eric and Cauzzi, Gianna and Culhane, J. Len and Curdt, Werner and Davila, Joseph M. and Del Zanna, Giulio and Doschek, George A. and Fineschi, Silvano and Fludra, Andrzej and Gallagher, Peter T. and Green, Lucie and Harra, Louise K. and Imada, Shinsuke and Innes, Davina and Kliem, Bernhard and Korendyke, Clarence and Mariska, John T. and Martinez-Pillet, Valentin and Parenti, Susanna and Patsourakos, Spiros and Peter, Hardi and Poletto, Luca and Rutten, Robert J. and Schuehle, Udo and Siemer, Martin and Shimizu, Toshifumi and Socas-Navarro, Hector and Solanki, Sami K. and Spadaro, Daniele and Trujillo-Bueno, Javier and Tsuneta, Saku and Dominguez, Santiago Vargas and Vial, Jean-Claude and Walsh, Robert and Warren, Harry P. and Wiegelmann, Thomas and Winter, Berend and Young, Peter}, title = {LEMUR large european module for solar ultraviolet research}, series = {Experimental astronomy : an international journal on astronomical instrumentation and data analysis}, volume = {34}, journal = {Experimental astronomy : an international journal on astronomical instrumentation and data analysis}, number = {2}, publisher = {Springer}, address = {Dordrecht}, issn = {0922-6435}, doi = {10.1007/s10686-011-9274-x}, pages = {273 -- 309}, year = {2012}, abstract = {The solar outer atmosphere is an extremely dynamic environment characterized by the continuous interplay between the plasma and the magnetic field that generates and permeates it. Such interactions play a fundamental role in hugely diverse astrophysical systems, but occur at scales that cannot be studied outside the solar system. Understanding this complex system requires concerted, simultaneous solar observations from the visible to the vacuum ultraviolet (VUV) and soft X-rays, at high spatial resolution (between 0.1'' and 0.3''), at high temporal resolution (on the order of 10 s, i.e., the time scale of chromospheric dynamics), with a wide temperature coverage (0.01 MK to 20 MK, from the chromosphere to the flaring corona), and the capability of measuring magnetic fields through spectropolarimetry at visible and near-infrared wavelengths. Simultaneous spectroscopic measurements sampling the entire temperature range are particularly important. These requirements are fulfilled by the Japanese Solar-C mission (Plan B), composed of a spacecraft in a geosynchronous orbit with a payload providing a significant improvement of imaging and spectropolarimetric capabilities in the UV, visible, and near-infrared with respect to what is available today and foreseen in the near future. The Large European Module for solar Ultraviolet Research (LEMUR), described in this paper, is a large VUV telescope feeding a scientific payload of high-resolution imaging spectrographs and cameras. LEMUR consists of two major components: a VUV solar telescope with a 30 cm diameter mirror and a focal length of 3.6 m, and a focal-plane package composed of VUV spectrometers covering six carefully chosen wavelength ranges between 170 and 1270 . The LEMUR slit covers 280'' on the Sun with 0.14'' per pixel sampling. In addition, LEMUR is capable of measuring mass flows velocities (line shifts) down to 2 km s (-aEuro parts per thousand 1) or better. LEMUR has been proposed to ESA as the European contribution to the Solar C mission.}, language = {en} } @article{WendtMolaro2012, author = {Wendt, Martin and Molaro, P.}, title = {QSO 0347-383 and the invariance of m(p)/m(e) in the course of cosmic time}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {541}, journal = {Astronomy and astrophysics : an international weekly journal}, number = {3}, publisher = {EDP Sciences}, address = {Les Ulis}, issn = {0004-6361}, doi = {10.1051/0004-6361/201218862}, pages = {8}, year = {2012}, abstract = {Context. The variation of the dimensionless fundamental physical constant mu = m(p)/m(e) - the proton to electron mass ratio - can be constrained via observation of Lyman and Werner lines of molecular hydrogen in the spectra of damped Lyman alpha systems (DLAs) in the line of sight to distant QSOs. Aims. Our intention is to maximize the possible precision of quasar absorption spectroscopy with regard to the investigation of the variation of the proton-to-electron mass-ratio mu. The demand for precision requires an understanding of the errors involved and effective techniques to handle present systematic errors. Methods. An analysis based on UVES high resolution data sets of QSO 0347-383 and its DLA is put forward and new approaches to some of the steps involved in the data analysis are introduced. We apply corrections for the observed offsets between discrete spectra and for the first time we find indications for inter-order distortions. Results. Drawing on VLT-UVES observations of QSO 0347-383 in 2009 our analysis yields Delta mu/mu = (4.3 +/- 7.2) x 10(-6) at z(abs) = 3.025. Conclusions. Current analyzes tend to underestimate the impact of systematic errors. Based on the scatter of the measured redshifts and the corresponding low significance of the redshift-sensitivity correlation we estimate the limit of accuracy of line position measurements to similar to 220 m s (1), consisting of roughly 150 m s (1) due to the uncertainty of the absorption line fit and about 150 m s (1) allocated to systematics related to instrumentation and calibration.}, language = {en} } @article{BlandHawthornEllisLeonSavaletal.2011, author = {Bland-Hawthorn, Joss and Ellis, S. C. and Leon-Saval, S. G. and Haynes, R. and Roth, Martin M. and L{\"o}hmannsr{\"o}ben, Hans-Gerd and Horton, A. J. and Cuby, J. -G. and Birks, T. A. and Lawrence, J. S. and Gillingham, P. and Ryder, S. D. and Trinh, C.}, title = {A complex multi-notch astronomical filter to suppress the bright infrared sky}, series = {Nature Communications}, volume = {2}, journal = {Nature Communications}, number = {50}, publisher = {Nature Publ. Group}, address = {London}, issn = {2041-1723}, doi = {10.1038/ncomms1584}, pages = {7}, year = {2011}, abstract = {A long-standing and profound problem in astronomy is the difficulty in obtaining deep near-infrared observations due to the extreme brightness and variability of the night sky at these wavelengths. A solution to this problem is crucial if we are to obtain the deepest possible observations of the early Universe, as redshifted starlight from distant galaxies appears at these wavelengths. The atmospheric emission between 1,000 and 1,800 nm arises almost entirely from a forest of extremely bright, very narrow hydroxyl emission lines that varies on timescales of minutes. The astronomical community has long envisaged the prospect of selectively removing these lines, while retaining high throughput between them. Here we demonstrate such a filter for the first time, presenting results from the first on-sky tests. Its use on current 8 m telescopes and future 30 m telescopes will open up many new research avenues in the years to come.}, language = {en} } @article{GreenSaxenaFeyzullayevHubertetal.2012, author = {Green-Saxena, A. and Feyzullayev, A. and Hubert, C. R. J. and Kallmeyer, Jens and Krueger, M. and Sauer, P. and Schulz, Hans-Martin and Orphan, V. J.}, title = {Active sulfur cycling by diverse mesophilic and thermophilic microorganisms in terrestrial mud volcanoes of Azerbaijan}, series = {Environmental microbiology}, volume = {14}, journal = {Environmental microbiology}, number = {12}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {1462-2912}, doi = {10.1111/1462-2920.12015}, pages = {3271 -- 3286}, year = {2012}, abstract = {Terrestrial mud volcanoes (TMVs) represent geochemically diverse habitats with varying sulfur sources and yet sulfur cycling in these environments remains largely unexplored. Here we characterized the sulfur-metabolizing microorganisms and activity in four TMVs in Azerbaijan. A combination of geochemical analyses, biological rate measurements and molecular diversity surveys (targeting metabolic genes aprA and dsrA and SSU ribosomal RNA) supported the presence of active sulfur-oxidizing and sulfate-reducing guilds in all four TMVs across a range of physiochemical conditions, with diversity of these guilds being unique to each TMV. The TMVs varied in potential sulfate reduction rates (SRR) by up to four orders of magnitude with highest SRR observed in sediments where in situ sulfate concentrations were highest. Maximum temperatures at which SRR were measured was 60 degrees C in two TMVs. Corresponding with these trends in SRR, members of the potentially thermophilic, spore-forming, Desulfotomaculum were detected in these TMVs by targeted 16S rRNA analysis. Additional sulfate-reducing bacterial lineages included members of the Desulfobacteraceae and Desulfobulbaceae detected by aprA and dsrA analyses and likely contributing to the mesophilic SRR measured. Phylotypes affiliated with sulfide-oxidizing Gamma- and Betaproteobacteria were abundant in aprA libraries from low sulfate TMVs, while the highest sulfate TMV harboured 16S rRNA phylotypes associated with sulfur-oxidizing Epsilonproteobacteria. Altogether, the biogeochemical and microbiological data indicate these unique terrestrial habitats support diverse active sulfur-cycling microorganisms reflecting the in situ geochemical environment.}, language = {en} } @article{CoelhoMahroTrincaoetal.2012, author = {Coelho, Catarina and Mahro, Martin and Trincao, Jose and Carvalho, Alexandra T. P. and Ramos, Maria Joao and Terao, Mineko and Garattini, Enrico and Leimk{\"u}hler, Silke and Romao, Maria Joao}, title = {The first mammalian aldehyde oxidase crystal structure insights into substrate specificity}, series = {The journal of biological chemistry}, volume = {287}, journal = {The journal of biological chemistry}, number = {48}, publisher = {American Society for Biochemistry and Molecular Biology}, address = {Bethesda}, issn = {0021-9258}, doi = {10.1074/jbc.M112.390419}, pages = {40690 -- 40702}, year = {2012}, abstract = {Aldehyde oxidases (AOXs) are homodimeric proteins belonging to the xanthine oxidase family of molybdenum-containing enzymes. Each 150-kDa monomer contains a FAD redox cofactor, two spectroscopically distinct [2Fe-2S] clusters, and a molybdenum cofactor located within the protein active site. AOXs are characterized by broad range substrate specificity, oxidizing different aldehydes and aromatic N-heterocycles. Despite increasing recognition of its role in the metabolism of drugs and xenobiotics, the physiological function of the protein is still largely unknown. We have crystallized and solved the crystal structure of mouse liver aldehyde oxidase 3 to 2.9 angstrom. This is the first mammalian AOX whose structure has been solved. The structure provides important insights into the protein active center and further evidence on the catalytic differences characterizing AOX and xanthine oxidoreductase. The mouse liver aldehyde oxidase 3 three-dimensional structure combined with kinetic, mutagenesis data, molecular docking, and molecular dynamics studies make a decisive contribution to understand the molecular basis of its rather broad substrate specificity.}, language = {en} } @article{JanssenArhonditsisBeusenetal.2015, author = {Janssen, Annette B. G. and Arhonditsis, George B. and Beusen, Arthur and Bolding, Karsten and Bruce, Louise and Bruggeman, Jorn and Couture, Raoul-Marie and Downing, Andrea S. and Elliott, J. Alex and Frassl, Marieke A. and Gal, Gideon and Gerla, Daan J. and Hipsey, Matthew R. and Hu, Fenjuan and Ives, Stephen C. and Janse, Jan H. and Jeppesen, Erik and Joehnk, Klaus D. and Kneis, David and Kong, Xiangzhen and Kuiper, Jan J. and Lehmann, Moritz K. and Lemmen, Carsten and Oezkundakci, Deniz and Petzoldt, Thomas and Rinke, Karsten and Robson, Barbara J. and Sachse, Rene and Schep, Sebastiaan A. and Schmid, Martin and Scholten, Huub and Teurlincx, Sven and Trolle, Dennis and Troost, Tineke A. and Van Dam, Anne A. and Van Gerven, Luuk P. A. and Weijerman, Mariska and Wells, Scott A. and Mooij, Wolf M.}, title = {Exploring, exploiting and evolving diversity of aquatic ecosystem models: a community perspective}, series = {Aquatic ecology : the international forum covering research in freshwater and marine environments}, volume = {49}, journal = {Aquatic ecology : the international forum covering research in freshwater and marine environments}, number = {4}, publisher = {Springer}, address = {Dordrecht}, issn = {1386-2588}, doi = {10.1007/s10452-015-9544-1}, pages = {513 -- 548}, year = {2015}, abstract = {Here, we present a community perspective on how to explore, exploit and evolve the diversity in aquatic ecosystem models. These models play an important role in understanding the functioning of aquatic ecosystems, filling in observation gaps and developing effective strategies for water quality management. In this spirit, numerous models have been developed since the 1970s. We set off to explore model diversity by making an inventory among 42 aquatic ecosystem modellers, by categorizing the resulting set of models and by analysing them for diversity. We then focus on how to exploit model diversity by comparing and combining different aspects of existing models. Finally, we discuss how model diversity came about in the past and could evolve in the future. Throughout our study, we use analogies from biodiversity research to analyse and interpret model diversity. We recommend to make models publicly available through open-source policies, to standardize documentation and technical implementation of models, and to compare models through ensemble modelling and interdisciplinary approaches. We end with our perspective on how the field of aquatic ecosystem modelling might develop in the next 5-10 years. To strive for clarity and to improve readability for non-modellers, we include a glossary.}, language = {en} } @article{AchillesFinkFischeretal.2016, author = {Achilles, E. I. S. and Fink, G. R. and Fischer, Martin H. and Dovern, A. and Held, A. and Timpert, D. C. and Schroeter, C. and Schuetz, K. and Kloetzsch, C. and Weiss, P. H.}, title = {Effect of meaning on apraxic finger imitation deficits}, series = {Neuropsychologia : an international journal in behavioural and cognitive neuroscience}, volume = {82}, journal = {Neuropsychologia : an international journal in behavioural and cognitive neuroscience}, publisher = {Elsevier}, address = {Oxford}, issn = {0028-3932}, doi = {10.1016/j.neuropsychologia.2015.12.022}, pages = {74 -- 83}, year = {2016}, abstract = {Apraxia typically results from left-hemispheric (LH), but also from right-hemispheric (RH) stroke, and often impairs gesture imitation. Especially in LH stroke, it is important to differentiate apraxia-induced gesture imitation deficits from those due to co-morbid aphasia and associated semantic deficits, possibly influencing the imitation of meaningful (MF) gestures. To explore this issue, we first investigated if the 10 supposedly meaningless (ML) gestures of a widely used finger imitation test really carry no meaning, or if the test also contains MF gestures, by asking healthy subjects (n=45) to classify these gestures as MF or ML. Most healthy subjects (98\%) classified three of the 10 gestures as clearly MF. Only two gestures were considered predominantly ML. We next assessed how imitation in stroke patients (255 LH, 113 RH stroke) is influenced by gesture meaning and how aphasia influences imitation of LH stroke patients (n=208). All patients and especially patients with imitation deficits (17\% of LH, 27\% of RH stroke patients) imitated MF gestures significantly better than ML gestures. Importantly, meaningfulness-scores of all 10 gestures significantly predicted imitation scores of patients with imitation deficits. Furthermore, especially in LH stroke patients with imitation deficits, the severity of aphasia significantly influenced the imitation of MF, but not ML gestures. Our findings in a large patient cohort support current cognitive models of imitation and strongly suggest that ML gestures are particularly sensitive to detect imitation deficits while minimising confounding effects of aphasia which affect the imitation of MF gestures in LH stroke patients. (C) 2015 Elsevier Ltd. All rights reserved.}, language = {en} } @article{OstermeyerKlemzKubinaetal.2002, author = {Ostermeyer, Martin and Klemz, Guido and Kubina, P. and Menzel, Ralf}, title = {Quasi-continuous-wave birefringence-compensated single- and double-rod Nd : YAG lasers}, year = {2002}, language = {en} } @article{KlemzKubinaOstermeyeretal.2001, author = {Klemz, Guido and Kubina, P. and Ostermeyer, Martin and Menzel, Ralf}, title = {Diode pumped high power TEM_00 Nd:YAG rod laser with birefringence compensation}, year = {2001}, language = {en} } @article{MiedemaMitznerGanschowetal.2017, author = {Miedema, P. S. and Mitzner, Rolf and Ganschow, S. and F{\"o}hlisch, Alexander and Beye, Martin}, title = {X-ray spectroscopy on the active ion in laser crystals}, series = {Physical chemistry, chemical physics : a journal of European Chemical Societies}, volume = {19}, journal = {Physical chemistry, chemical physics : a journal of European Chemical Societies}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1463-9076}, doi = {10.1039/c7cp03026f}, pages = {21800 -- 21806}, year = {2017}, abstract = {The active ions in typical laser crystals were studied with Resonant Inelastic X-ray Scattering (RIXS) and Partial Fluorescence Yield X-ray Absorption (PFY-XAS) spectroscopies as solid state model systems for dilute active centers. We analyzed Ti3+ and Cr3+ in alpha-Al2O3:Ti3+ and LiCaAlF6:Cr3+, respectively. The comparison of experimental data with semi-empirical multiplet calculations provides insights into the electronic structure and shows how measured crystal field energies are related across different spectroscopies.}, language = {en} } @article{SaremAryaHeizmannetal.2018, author = {Sarem, Melika and Arya, Neha and Heizmann, Miriam and Neffe, Axel T. and Barbero, Andrea and Gebauer, Tim P. and Martin, Ivan and Lendlein, Andreas and Shastri, V. Prasad}, title = {Interplay between stiffness and degradation of architectured gelatin hydrogels leads to differential modulation of chondrogenesis in vitro and in vivo}, series = {Acta biomaterialia}, volume = {69}, journal = {Acta biomaterialia}, publisher = {Elsevier}, address = {Oxford}, issn = {1742-7061}, doi = {10.1016/j.actbio.2018.01.025}, pages = {83 -- 94}, year = {2018}, abstract = {The limited capacity of cartilage to heal large lesions through endogenous mechanisms has led to extensive effort to develop materials to facilitate chondrogenesis. Although physical-chemical properties of biomaterials have been shown to impact in vitro chondrogenesis, whether these findings are translatable in vivo is subject of debate. Herein, architectured 3D hydrogel scaffolds (ArcGel) (produced by crosslinking gelatin with ethyl lysine diisocyanate (LDI)) were used as a model system to investigate the interplay between scaffold mechanical properties and degradation on matrix deposition by human articular chondrocytes (HAC) from healthy donors in vitro and in vivo. Using ArcGel scaffolds of different tensile and shear modulus, and degradation behavior; in this study, we compared the fate of ex vivo engineeredArcGels-chondrocytes constructs, i.e. the traditional tissue engineering approach, with the de novo formation of cartilaginous tissue in HAC laden ArcGels in an ectopic nude mouse model. While the softer and fast degrading ArcGel (LNCO3) was more efficient at promoting chondrogenic differentiation in vitro, upon ectopic implantation, the stiffer and slow degrading ArcGel (LNCO8) was superior in maintaining chondrogenic phenotype in HAC and retention of cartilaginous matrix. Furthermore, surprisingly the de novo formation of cartilage tissue was promoted only in LNCO8. Since HAC cultured for only three days in the LNCO8 environment showed upregulation of hypoxia-associated genes, this suggests a potential role for hypoxia in the observed in vivo outcomes. In summary, this study sheds light on how immediate environment (in vivo versus in vitro) can significantly impact the outcomes of cell-laden biomaterials. Statement of Significance In this study, 3D architectured hydrogels (ArcGels) with different mechanical and biodegradation properties were investigated for their potential to promote formation of cartilaginous matrix by human articular chondrocytes in vitro and in vivo. Two paradigms were explored (i) ex vivo engineering followed by in vivo implantation in ectopic site of nude mice and (ii) short in vitro culture (3 days) followed by implantation to induce de novo cartilage formation. Softer and fast degrading ArcGel were better at promoting chondrogenesis in vitro, while stiffer and slow degrading ArcGel were strikingly superior in both maintaining chondrogenesis in vivo and inducing de novo formation of cartilage. Our findings highlight the importance of the interplay between scaffold mechanics and degradation in chondrogenesis.}, language = {en} } @article{OttenKnoxBouldayetal.2018, author = {Otten, Cecile and Knox, Jessica and Boulday, Gwenola and Eymery, Mathias and Haniszewski, Marta and Neuenschwander, Martin and Radetzki, Silke and Vogt, Ingo and Haehn, Kristina and De Luca, Coralie and Cardoso, Cecile and Hamad, Sabri and Igual Gil, Carla and Roy, Peter and Albiges-Rizo, Corinne and Faurobert, Eva and von Kries, Jens P. and Campillos, Monica and Tournier-Lasserve, Elisabeth and Derry, William Brent and Abdelilah-Seyfried, Salim}, title = {Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations}, series = {EMBO molecular medicine}, volume = {10}, journal = {EMBO molecular medicine}, number = {10}, publisher = {Wiley}, address = {Hoboken}, issn = {1757-4676}, doi = {10.15252/emmm.201809155}, pages = {17}, year = {2018}, abstract = {Cerebral cavernous malformations (CCMs) are vascular lesions in the central nervous system causing strokes and seizures which currently can only be treated through neurosurgery. The disease arises through changes in the regulatory networks of endothelial cells that must be comprehensively understood to develop alternative, non-invasive pharmacological therapies. Here, we present the results of several unbiased small-molecule suppression screens in which we applied a total of 5,268 unique substances to CCM mutant worm, zebrafish, mouse, or human endothelial cells. We used a systems biology-based target prediction tool to integrate the results with the whole-transcriptome profile of zebrafish CCM2 mutants, revealing signaling pathways relevant to the disease and potential targets for small-molecule-based therapies. We found indirubin-3-monoxime to alleviate the lesion burden in murine preclinical models of CCM2 and CCM3 and suppress the loss-of-CCM phenotypes in human endothelial cells. Our multi-organism-based approach reveals new components of the CCM regulatory network and foreshadows novel small-molecule-based therapeutic applications for suppressing this devastating disease in patients.}, language = {en} } @article{BronnerLeyssnerStremlauetal.2012, author = {Bronner, C. and Leyssner, F. and Stremlau, S. and Utecht, Manuel Martin and Saalfrank, Peter and Klamroth, Tillmann and Tegeder, P.}, title = {Electronic structure of a subnanometer wide bottom-up fabricated graphene nanoribbon: End states, band gap, and dispersion}, series = {Physical review : B, Condensed matter and materials physics}, volume = {86}, journal = {Physical review : B, Condensed matter and materials physics}, number = {8}, publisher = {American Physical Society}, address = {College Park}, issn = {1098-0121}, doi = {10.1103/PhysRevB.86.085444}, pages = {5}, year = {2012}, abstract = {Angle-resolved two-photon photoemission and high-resolution electron energy loss spectroscopy are employed to derive the electronic structure of a subnanometer atomically precise quasi-one-dimensional graphene nanoribbon (GNR) on Au(111). We resolved occupied and unoccupied electronic bands including their dispersion and determined the band gap, which possesses an unexpectedly large value of 5.1 eV. Supported by density functional theory calculations for the idealized infinite polymer and finite size oligomers, an unoccupied nondispersive electronic state with an energetic position in the middle of the band gap of the GNR could be identified. This state resides at both ends of the ribbon (end state) and is only found in the finite sized systems, i.e., the oligomers.}, language = {en} } @misc{DoegeHoenzkeSchumacheretal.2016, author = {Doege, N. and Hoenzke, S. and Schumacher, Fabian and Balzus, Benjamin and Colombo, Miriam and Hadam, S. and Rancan, F. and Blume-Peytavi, Ulrike and Schindler, A. and Ruehl, E. and Skov, P. and Church, Martin K. and Hedtrich, Sarah and Kleuser, Burkhard and Bodmeier, Roland and Vogt, A.}, title = {Ex vivo microdialysis used for the preclinical assessment of anti-inflammatory therapy}, series = {Experimental dermatology : the official journal of the European Immunodermatology Society}, volume = {25}, journal = {Experimental dermatology : the official journal of the European Immunodermatology Society}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {0906-6705}, pages = {E32 -- E32}, year = {2016}, language = {en} } @article{SellbergMcQueenLaksmonoetal.2015, author = {Sellberg, Jonas A. and McQueen, Trevor A. and Laksmono, Hartawan and Schreck, Simon and Beye, Martin and DePonte, Daniel P. and Kennedy, Brian and Nordlund, Dennis and Sierra, Raymond G. and Schlesinger, Daniel and Tokushima, Takashi and Zhovtobriukh, Iurii and Eckert, Sebastian and Segtnan, Vegard H. and Ogasawara, Hirohito and Kubicek, Katharina and Techert, Simone and Bergmann, Uwe and Dakovski, Georgi L. and Schlotter, William F. and Harada, Yoshihisa and Bogan, Michael J. and Wernet, Philippe and F{\"o}hlisch, Alexander and Pettersson, Lars G. M. and Nilsson, Anders}, title = {X-ray emission spectroscopy of bulk liquid water in "no-man's land"}, series = {The journal of chemical physics : bridges a gap between journals of physics and journals of chemistr}, volume = {142}, journal = {The journal of chemical physics : bridges a gap between journals of physics and journals of chemistr}, number = {4}, publisher = {American Institute of Physics}, address = {Melville}, issn = {0021-9606}, doi = {10.1063/1.4905603}, pages = {9}, year = {2015}, abstract = {The structure of bulk liquid water was recently probed by x-ray scattering below the temperature limit of homogeneous nucleation (T-H) of similar to 232 K [J. A. Sellberg et al., Nature 510, 381-384 (2014)]. Here, we utilize a similar approach to study the structure of bulk liquid water below T-H using oxygen K-edge x-ray emission spectroscopy (XES). Based on previous XES experiments [T. Tokushima et al., Chem. Phys. Lett. 460, 387-400 (2008)] at higher temperatures, we expected the ratio of the 1b(1)' and 1b(1)" peaks associated with the lone-pair orbital in water to change strongly upon deep supercooling as the coordination of the hydrogen (H-) bonds becomes tetrahedral. In contrast, we observed only minor changes in the lone-pair spectral region, challenging an interpretation in terms of two interconverting species. A number of alternative hypotheses to explain the results are put forward and discussed. Although the spectra can be explained by various contributions from these hypotheses, we here emphasize the interpretation that the line shape of each component changes dramatically when approaching lower temperatures, where, in particular, the peak assigned to the proposed disordered component would become more symmetrical as vibrational interference becomes more important. (C) 2015 AIP Publishing LLC.}, language = {en} } @article{EckertMiedemaQuevedoetal.2016, author = {Eckert, Sebastian and Miedema, P. S. and Quevedo, W. and Fondell, Mattis and Beye, Martin and Pietzsch, Annette and Ross, M. and Khalil, M. and F{\"o}hlisch, Alexander}, title = {Molecular structures and protonation state of 2-Mercaptopyridine in aqueous solution}, series = {Chemical physics letters}, volume = {647}, journal = {Chemical physics letters}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0009-2614}, doi = {10.1016/j.cplett.2016.01.050}, pages = {103 -- 106}, year = {2016}, abstract = {The speciation of 2-Mercaptopyridine in aqueous solution has been investigated with nitrogen 1s Near Edge X-ray Absorption Fine Structure spectroscopy and time dependent Density Functional Theory. The prevalence of distinct species as a function of the solvent basicity is established. No indications of dimerization towards high concentrations are found. The determination of different molecular structures of 2-Mercaptopyridine in aqueous solution is put into the context of proton-transfer in keto-enol and thione-thiol tautomerisms. (C) 2016 The Authors. Published by Elsevier B.V.}, language = {en} } @article{SchreckBeyeSellbergetal.2014, author = {Schreck, Simon and Beye, Martin and Sellberg, Jonas A. and McQueen, Trevor and Laksmono, Hartawan and Kennedy, Brian and Eckert, Sebastian and Schlesinger, Daniel and Nordlund, Dennis and Ogasawara, Hirohito and Sierra, Raymond G. and Segtnan, Vegard H. and Kubicek, Katharina and Schlotter, William F. and Dakovski, Georgi L. and Moeller, Stefan P. and Bergmann, Uwe and Techert, Simone and Pettersson, Lars G. M. and Wernet, Philippe and Bogan, Michael J. and Harada, Yoshihisa and Nilsson, Anders and F{\"o}hlisch, Alexander}, title = {Reabsorption of soft x-ray emission at high x-ray free-electron laserfluences}, series = {Physical review letters}, volume = {113}, journal = {Physical review letters}, number = {15}, publisher = {American Physical Society}, address = {College Park}, issn = {0031-9007}, doi = {10.1103/PhysRevLett.113.153002}, pages = {6}, year = {2014}, abstract = {We report on oxygen K-edge soft x-ray emission spectroscopy from a liquid water jet at the Linac Coherent Light Source. We observe significant changes in the spectral content when tuning over a wide range of incident x-ray fluences. In addition the total emission yield decreases at high fluences. These modifications result from reabsorption of x-ray emission by valence-excited molecules generated by the Auger cascade. Our observations have major implications for future x-ray emission studies at intense x-ray sources. We highlight the importance of the x-ray pulse length with respect to the core-hole lifetime.}, language = {en} } @article{PerezLopezMartinVelazquezSanchezMoraletal.2017, author = {Perez-Lopez, Raul and Martin-Velazquez, Saul and Sanchez-Moral, Sergio and Patyniak, Magda and Lopez-Gutierrez, Jose and Cuezva, Soledad and Lario, J. and Silva, P. G. and Rodriguez-Pascua, M. A. and Giner-Robles, J. L.}, title = {New insights on speleoseismology: The geothermal gradient and heat flow values in caves for the study of active faults}, series = {Quaternary international : the journal of the International Union for Quaternary Research}, volume = {451}, journal = {Quaternary international : the journal of the International Union for Quaternary Research}, publisher = {Elsevier}, address = {Oxford}, issn = {1040-6182}, doi = {10.1016/j.quaint.2016.11.026}, pages = {165 -- 175}, year = {2017}, abstract = {Normally in paleoseismology, the study of the tectonic slip-rate is performed in trenches on the fault scarp, or by the estimation of fault movements from the geomorphic features. In this work, we have carried out a paleoseismic analysis of the Benis Fault, located in southeast Spain, combined with a geothermal analysis inside a deep cave related to the fault (-350 m). Thus, we have estimated the last earthquake magnitude and time of occurrence from evidence of ceiling collapse and displaced carbonate blocks inside a cave, which is developed across the fault. The magnitude was obtained from the application of the empirical relationship of the fault parameters and coseismic vertical displacement, yielding a value ranging between M 5.9 and M 6.5. Moreover, we dated this paleoearthquake by the paleontological record of a "Lynx pardinus spelaea", with an age of 65 +/- 18 ka BP. Additionally, we have measured the thermal profile of the Benis Cave (-350 m of depth), from single rock point temperature measurements during 2 years. The temperature profile shows three different parts inside the cave, the shallow heterogeneous thermal zone till 50 m depth; the homogeneous thermal zone 150 m till with constant temperature and the hetero-thermal deep zone, deeper than 150 m and till the deepest zone (350 m). Furthermore, we have estimated the Vertical Geothermal Gradient, 1.85 degrees C/100 m for the deepest zone (-150; -290 m). The temperature increases with depth, showing a reverse thermal profile in comparison with normal gradients in deep caves. Finally, we have calculated the heat flux of 0.46 mWm(2). (C) 2016 Elsevier Ltd and INQUA. All rights reserved.}, language = {en} } @article{JumaAkalaEyaseetal.2011, author = {Juma, Wanyama P. and Akala, Hoseah M. and Eyase, Fredrick L. and Muiva, Lois M. and Heydenreich, Matthias and Okalebo, Faith A. and Gitu, Peter M. and Peter, Martin G. and Walsh, Douglas S. and Imbuga, Mabel and Yenesew, Abiy}, title = {Terpurinflavone an antiplasmodial flavone from the stem of Tephrosia Purpurea}, series = {Phytochemistry letters}, volume = {4}, journal = {Phytochemistry letters}, number = {2}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1874-3900}, doi = {10.1016/j.phytol.2011.02.010}, pages = {176 -- 178}, year = {2011}, abstract = {The stem extract of Tephrosia purpurea showed antiplasmodial activity against the D6 (chloroquine-sensitive) and W2 (chloroquine-resistant) strains of Plasmodium falciparum with IC(50) values of 10.47 +/- 2.22 mu g/ml and 12.06 +/- 2.54 mu g/ml, respectively. A new prenylated flavone, named terpurinflavone, along with the known compounds lanceolatin A, (-)-semiglabrin and lanceolatin B have been isolated from this extract. The new compound, terpurinflavone, showed the highest antiplasmodial activity with IC(50) values of 3.12 +/- 0.28 mu M (D6) and 6.26 +/- 2.66 mu M (W2). The structures were determined on the basis of spectroscopic evidence.}, language = {en} } @article{RichterNuzaFoxetal.2017, author = {Richter, Philipp and Nuza, S. E. and Fox, Andrew J. and Wakker, Bart P. and Lehner, N. and Ben Bekhti, Nadya and Fechner, Cora and Wendt, Martin and Howk, J. Christopher and Muzahid, S. and Ganguly, R. and Charlton, Jane C.}, title = {An HST/COS legacy survey of high-velocity ultraviolet absorption in the}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {607}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, issn = {1432-0746}, doi = {10.1051/0004-6361/201630081}, pages = {90}, year = {2017}, abstract = {Context. The Milky Way is surrounded by large amounts of diffuse gaseous matter that connects the stellar body of our Galaxy with its large-scale Local Group (LG) environment. Aims. To characterize the absorption properties of this circumgalactic medium (CGM) and its relation to the LG we present the so-far largest survey of metal absorption in Galactic high-velocity clouds (HVCs) using archival ultraviolet (UV) spectra of extragalactic background sources. The UV data are obtained with the Cosmic Origins Spectrograph (COS) onboard the Hubble Space Telescope (HST) and are supplemented by 21 cm radio observations of neutral hydrogen. Methods. Along 270 sightlines we measure metal absorption in the lines of Si II, Si III, C II, and C IV and associated H I 21 cm emission in HVCs in the velocity range vertical bar v(LSR)vertical bar = 100-500 km s(-1). With this unprecedented large HVC sample we were able to improve the statistics on HVC covering fractions, ionization conditions, small-scale structure, CGM mass, and inflow rate. For the first time, we determine robustly the angular two point correlation function of the high-velocity absorbers, systematically analyze antipodal sightlines on the celestial sphere, and compare the HVC absorption characteristics with that of damped Lyman alpha absorbers (DLAs) and constrained cosmological simulations of the LG (CLUES project).}, language = {en} } @article{GlaeserBolteMartinetal.2013, author = {Gl{\"a}ser, Stefanie P. and Bolte, Kathrin and Martin, Karin and Busse, Hans-J{\"u}rgen and Grossart, Hans-Peter and K{\"a}mpfer, Peter and Gl{\"a}ser, Jens}, title = {Novosphingobium fuchskuhlense sp nov., isolated from the north-east basin of Lake Grosse Fuchskuhle}, series = {International journal of systematic and evolutionary microbiology}, volume = {63}, journal = {International journal of systematic and evolutionary microbiology}, publisher = {Society for General Microbiology}, address = {Reading}, issn = {1466-5026}, doi = {10.1099/ijs.0.043083-0}, pages = {586 -- 592}, year = {2013}, abstract = {A yellow pigmented, Gram-negative, rod-shaped bacterium designated FNE08-7(T) was isolated from subsurface water of the north-east basin of the bog lake Grosse Fuchskuhle (Brandenburg, Germany). A first analysis of the nearly full-length 16S rRNA gene sequence analysis including environmental 16S rRNA gene sequences derived from freshwater ecosystems showed that strain FNE08-7(T) is the first cultured representative, to our knowledge, of the freshwater tribe Novo-A2. Further analysis indicates highest 16S rRNA gene sequence similarities to the type strains of Novosphingobium stygium (98.0\%) and Novosphingobium taihuense (97.4\%) and between 94.0\% and 96.9\% sequence similarity to other members of the genus Novosphingobium. Reconstruction of phylogenetic trees showed that strain FNE08-7(T) formed a distinct cluster with the type strains of N. stygium and N. taihuense supported by high bootstrap values. DNA DNA hybridization of strain FNE08-7(T) with N. stygium SMCC B0712(T) and N. taihuense DSM 17507(T) revealed low similarity values of 18.4\% (reciprocal: 11.4\%) and 23.1\% (reciprocal: 54.2\%), respectively. The predominant fatty acid of the isolate is C-18:1 omega 7c (56.4\%) and two characteristic 2-hydroxy fatty acids, C-14:0 2-OH (16.5\%) and C-15:0 2-OH (3.3\%) occur. Ubiquinone Q-10 is the major respiratory quinone. The predominant polar lipids are phosphatidylethanolamine, phosphatidylmethylethanolamine, phosphatidylglycerol, sphingoglycolipid, phosphatidylcholine and minor amounts of diphosphatidylglycerol. Spermidine is the predominant polyamine. Characterization by genotypic, chemotaxonomic and phenotypic analysis indicate that strain FNE08-7(T) represents a novel species of the genus Novosphingobium within the Alphaproteobacteria. Therefore, we propose the species Novosphingobium fuchskuhlense sp. nov., with FNE08-7(T) (=DSM 25065(T)=CCM 7978(T)=CCUG 61508(T)) as the type strain.}, language = {en} } @article{StolbovaMartinBookhagenetal.2014, author = {Stolbova, Veronika and Martin, P. and Bookhagen, Bodo and Marwan, Norbert and Kurths, J{\"u}rgen}, title = {Topology and seasonal evolution of the network of extreme precipitation over the Indian subcontinent and Sri Lanka}, series = {Nonlinear processes in geophysics}, volume = {21}, journal = {Nonlinear processes in geophysics}, number = {4}, publisher = {Copernicus}, address = {G{\"o}ttingen}, issn = {1023-5809}, doi = {10.5194/npg-21-901-2014}, pages = {901 -- 917}, year = {2014}, abstract = {This paper employs a complex network approach to determine the topology and evolution of the network of extreme precipitation that governs the organization of extreme rainfall before, during, and after the Indian Summer Monsoon (ISM) season. We construct networks of extreme rainfall events during the ISM (June-September), post-monsoon (October-December), and pre-monsoon (March-May) periods from satellite-derived (Tropical Rainfall Measurement Mission, TRMM) and rain-gauge interpolated (Asian Precipitation Highly Resolved Observational Data Integration Towards the Evaluation of Water Resources, APHRODITE) data sets. The structure of the networks is determined by the level of synchronization of extreme rainfall events between different grid cells throughout the Indian subcontinent. Through the analysis of various complex-network metrics, we describe typical repetitive patterns in North Pakistan (NP), the Eastern Ghats (EG), and the Tibetan Plateau (TP). These patterns appear during the pre-monsoon season, evolve during the ISM, and disappear during the post-monsoon season. These are important meteorological features that need further attention and that may be useful in ISM timing and strength prediction.}, language = {en} } @misc{GuerreroChuHamannetal.2011, author = {Guerrero, Mart{\´i}n A. and Chu, You-Hua and Hamann, Wolf-Rainer and Oskinova, Lida and Sch{\"o}nberner, Detlef and Todt, Helge Tobias and Steffen, Matthias and Ruiz, Nieves and Gruendl, Robert A. and Blair, William P.}, title = {Ablation and wind mass-loading in the born-again planetary nebula A 30}, series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, number = {563}, issn = {1866-8372}, doi = {10.25932/publishup-41234}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-412341}, pages = {2}, year = {2011}, abstract = {We present XMM-Newton and Chandra observations of the born-again planetary nebula A 30. These X-ray observations reveal a bright unresolved source at the position of the central star whose X-ray luminosity exceeds by far the model expectations for photospheric emission and for shocks within the stellar wind. We suggest that a "born-again hot bubble" may be responsible for this X-ray emission. Diffuse X-ray emission associated with the petal-like features and one of the H-poor knots seen in the optical is also found. The weakened emission of carbon lines in the spectrum of the diffuse emission can be interpreted as the dilution of stellar wind by mass-loading or as the detection of material ejected during a very late thermal pulse.}, language = {en} } @article{GuerreroRuizHamannetal.2012, author = {Guerrero, Mart{\´i}n A. and Ruiz, N. and Hamann, Wolf-Rainer and Chu, Y.-H. and Todt, Helge Tobias and Sch{\"o}nberner, Detlef and Oskinova, Lida and Gr{\"u}ndl, R. A. and Steffen, M. and Blair, William P. and Toala, Jes{\´u}s Alberto}, title = {Rebirth of X-Ray emission from the born-again planetary Nebula A30}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, volume = {755}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, number = {2}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {0004-637X}, doi = {10.1088/0004-637X/755/2/129}, pages = {15}, year = {2012}, abstract = {The planetary nebula A30 is believed to have undergone a very late thermal pulse resulting in the ejection of knots of hydrogen-poor material. Using multi-epoch Hubble Space Telescope images, we have detected the angular expansion of these knots and derived an age of 850(-150)(+280) yr. To investigate the spectral and spatial properties of the soft X-ray emission detected by ROSAT, we have obtained Chandra and XMM-Newton deep observations of A30. The X-ray emission from A30 can be separated into two components: a point source at the central star and diffuse emission associated with the hydrogen-poor knots and the cloverleaf structure inside the nebular shell. To help us assess the role of the current stellar wind in powering this X-ray emission, we have determined the stellar parameters and wind properties of the central star of A30 using a non-LTE model fit to its optical and UV spectra. The spatial distribution and spectral properties of the diffuse X-ray emission are highly suggestive that it is generated by the post-born-again and present fast stellar winds interacting with the hydrogen-poor ejecta of the born-again event. This emission can be attributed to shock-heated plasma, as the hydrogen-poor knots are ablated by the stellar winds, under which circumstances the efficient mass loading of the present fast stellar wind raises its density and damps its velocity to produce the observed diffuse soft X-rays. Charge transfer reactions between the ions of the stellar winds and material of the born-again ejecta have also been considered as a possible mechanism for the production of diffuse X-ray emission, and upper limits on the expected X-ray production by this mechanism have been derived. The origin of the X-ray emission from the central star of A30 is puzzling: shocks in the present fast stellar wind and photospheric emission can be ruled out, while the development of a new, compact hot bubble confining the fast stellar wind seems implausible.}, language = {en} } @article{FangGuerreroMarquezLugoetal.2014, author = {Fang, X. and Guerrero, Mart{\´i}n A. and Marquez-Lugo, R. A. and Toala, Jes{\´u}s Alberto and Arthur, S. J. and Chu, Y.-H. and Blair, William P. and Gruendl, R. A. and Hamann, Wolf-Rainer and Oskinova, Lida and Todt, Helge Tobias}, title = {Expansion of hydrogen-poor knots in the born-again planetary nebulae A30 and A78}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, volume = {797}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, number = {2}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {0004-637X}, doi = {10.1088/0004-637X/797/2/100}, pages = {11}, year = {2014}, abstract = {We analyze the expansion of hydrogen-poor knots and filaments in the born-again planetary nebulae A30 and A78 based on Hubble Space Telescope ( HST) images obtained almost 20 yr apart. The proper motion of these features generally increases with distance to the central star, but the fractional expansion decreases, i.e., the expansion is not homologous. As a result, there is not a unique expansion age, which is estimated to be 610-950 yr for A30 and 600-1140 yr for A78. The knots and filaments have experienced complex dynamical processes: the current fast stellar wind is mass loaded by the material ablated from the inner knots; the ablated material is then swept up until it shocks the inner edges of the outer, hydrogen-rich nebula. The angular expansion of the outer filaments shows a clear dependence on position angle, indicating that the interaction of the stellar wind with the innermost knots channels the wind along preferred directions. The apparent angular expansion of the innermost knots seems to be dominated by the rocket effect of evaporating gas and by the propagation of the ionization front inside them. Radiation-hydrodynamical simulations show that a single ejection of material followed by a rapid onset of the stellar wind and ionizing flux can reproduce the variety of clumps and filaments at different distances from the central star found in A30 and A78.}, language = {en} } @article{NishikawaHardeeZhangetal.2013, author = {Nishikawa, Ken-Ichi and Hardee, P. and Zhang, B. and Dutan, I. and Medvedev, M. and Choi, E. J. and Min, K. W. and Niemiec, J. and Mizuno, Y. and Nordlund, Ake and Frederiksen, Jacob Trier and Sol, H. and Pohl, Martin and Hartmann, D. H.}, title = {Magnetic field generation in a jet-sheath plasma via the kinetic Kelvin-Helmholtz instability}, series = {Annales geophysicae}, volume = {31}, journal = {Annales geophysicae}, number = {9}, publisher = {Copernicus}, address = {G{\"o}ttingen}, issn = {0992-7689}, doi = {10.5194/angeo-31-1535-2013}, pages = {1535 -- 1541}, year = {2013}, abstract = {We have investigated the generation of magnetic fields associated with velocity shear between an unmagnetized relativistic jet and an unmagnetized sheath plasma. We have examined the strong magnetic fields generated by kinetic shear (Kelvin-Helmholtz) instabilities. Compared to the previous studies using counter-streaming performed by Alves et al. (2012), the structure of the kinetic Kelvin-Helmholtz instability (KKHI) of our jet-sheath configuration is slightly different, even for the global evolution of the strong transverse magnetic field. In our simulations the major components of growing modes are the electric field E-z, perpendicular to the flow boundary, and the magnetic field B-y, transverse to the flow direction. After the B-y component is excited, an induced electric field E-x, parallel to the flow direction, becomes significant. However, other field components remain small. We find that the structure and growth rate of KKHI with mass ratios m(i)/m(e) = 1836 and m(i)/m(e) = 20 are similar. In our simulations in the nonlinear stage is not as clear as in counter-streaming cases. The growth rate for a mildly-relativistic jet case (gamma(j) = 1.5) is larger than for a relativistic jet case (gamma(j) = 15).}, language = {en} } @article{NishikawaFrederiksenNordlundetal.2016, author = {Nishikawa, Ken-Ichi and Frederiksen, J. T. and Nordlund, A. and Mizuno, Y. and Hardee, P. E. and Niemiec, J. and Gomez, J. L. and Dutan, I. and Meli, A. and Sol, H. and Pohl, Martin and Hartmann, D. H.}, title = {EVOLUTION OF GLOBAL RELATIVISTIC JETS: COLLIMATIONS AND EXPANSION WITH kKHI AND THE WEIBEL INSTABILITY}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, volume = {820}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {0004-637X}, doi = {10.3847/0004-637X/820/2/94}, pages = {14}, year = {2016}, abstract = {In the study of relativistic jets one of the key open questions is their interaction with the environment. Here. we study the initial evolution of both electron-proton (e(-) - p(+)) and electron-positron (e(+/-)) relativistic jets, focusing on their lateral interaction with ambient plasma. We follow the evolution of toroidal magnetic fields generated by both the kinetic Kelvin-Helmholtz and Mushroom instabilities. For an e(-) - p(+) jet, the induced magnetic field collimates the jet and electrons are perpendicularly accelerated. As the instabilities saturate and subsequently weaken, the magnetic polarity switches from clockwise to counterclockwise in the middle of the jet. For an e(+/-) jet, we find strong mixing of electrons and positrons with the ambient plasma, resulting in the creation of a bow shock. The merging of current filaments generates density inhomogeneities that. initiate a forward shock. Strong jet-ambient plasma mixing prevents a full development of the jet (on the scale studied), revealing evidence for both jet collimation and particle acceleration in the forming bow shock. Differences in the magnetic field structure generated by e(-) - p(+) and e(+/-) jets may contribute to the polarization properties of the observed emission in AGN jets and gamma-ray bursts.}, language = {en} } @article{NishikawaHardeeDutanetal.2014, author = {Nishikawa, Ken-Ichi and Hardee, P. E. and Dutan, I. and Niemiec, J. and Medvedev, M. and Mizuno, Y. and Meli, A. and Sol, H. and Zhang, B. and Pohl, Martin and Hartmann, D. H.}, title = {Magnetic agnetic field generation in core-sheath jets via the kinetic Kelvin-Helmholtz instability}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, volume = {793}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, number = {1}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {0004-637X}, doi = {10.1088/0004-637X/793/1/60}, pages = {16}, year = {2014}, abstract = {We have investigated magnetic field generation in velocity shears via the kinetic Kelvin-Helmholtz instability (kKHI) using a relativistic plasma jet core and stationary plasma sheath. Our three-dimensional particle-in-cell simulations consider plasma jet cores with Lorentz factors of 1.5, 5, and 15 for both electron-proton and electron-positron plasmas. For electron-proton plasmas, we find generation of strong large-scale DC currents and magnetic fields that extend over the entire shear surface and reach thicknesses of a few tens of electron skin depths. For electron-positron plasmas, we find generation of alternating currents and magnetic fields. Jet and sheath plasmas are accelerated across the shear surface in the strong magnetic fields generated by the kKHI. The mixing of jet and sheath plasmas generates a transverse structure similar to that produced by the Weibel instability.}, language = {en} } @article{DelahayeFiassonPohletal.2011, author = {Delahaye, T. and Fiasson, A. and Pohl, Martin and Salati, P.}, title = {The GeV-TeV Galactic gamma-ray diffuse emission I. Uncertainties in the predictions of the hadronic component}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {531}, journal = {Astronomy and astrophysics : an international weekly journal}, number = {4}, publisher = {EDP Sciences}, address = {Les Ulis}, issn = {0004-6361}, doi = {10.1051/0004-6361/201116647}, pages = {19}, year = {2011}, abstract = {Context. The Galactic gamma-ray diffuse emission is currently observed in the GeV-TeV energy range with unprecedented accuracy by the Fermi satellite. Understanding this component is crucial because it provides a background to many different signals, such as extragalactic sources or annihilating dark matter. It is timely to reinvestigate how it is calculated and to assess the various uncertainties that are likely to affect the accuracy of the predictions. Aims. The Galactic gamma-ray diffuse emission is mostly produced above a few GeV by the interactions of cosmic ray primaries impinging on the interstellar material. The theoretical error on that component is derived by exploring various potential sources of uncertainty. Particular attention is paid to cosmic ray propagation. Nuclear cross sections, the proton and helium fluxes at the Earth's position, the Galactic radial profile of supernova remnants, and the hydrogen distribution can also severely affect the signal. Methods. The propagation of cosmic ray species throughout the Galaxy is described in the framework of a semi-analytic two-zone diffusion/convection model. The gamma-ray flux is reliably and quickly determined. This allows conversion of the constraints set by the boron-to-carbon data into a theoretical uncertainty on the diffuse emission. New deconvolutions of the HI and CO sky maps are also used to get the hydrogen distribution within the Galaxy. Results. The thickness of the cosmic ray diffusive halo is found to have a significant effect on the Galactic gamma-ray diffuse emission, while the interplay between diffusion and convection has little influence on the signal. The uncertainties related to nuclear cross sections and to the primary cosmic ray fluxes at the Earth are significant. The radial distribution of supernova remnants along the Galactic plane turns out to be a key ingredient. As expected, the predictions are extremely sensitive to the spatial distribution of hydrogen within the Milky Way. Conclusions. Most of the sources of uncertainty are likely to be reduced in the near future. The stress should be put (i) on better determination of the thickness of the cosmic ray diffusive halo; and (ii) on refined observations of the radial profile of supernova remnants.}, language = {en} } @article{BarnettWestburySandovalVelascoetal.2020, author = {Barnett, Ross and Westbury, Michael V. and Sandoval-Velasco, Marcela and Vieira, Filipe Garrett and Jeon, Sungwon and Zazula, Grant and Martin, Michael D. and Ho, Simon Y. W. and Mather, Niklas and Gopalakrishnan, Shyam and Ramos-Madrigal, Jazmin and de Manuel, Marc and Zepeda-Mendoza, M. Lisandra and Antunes, Agostinho and Baez, Aldo Carmona and De Cahsan, Binia and Larson, Greger and O'Brien, Stephen J. and Eizirik, Eduardo and Johnson, Warren E. and Koepfli, Klaus-Peter and Wilting, Andreas and Fickel, J{\"o}rns and Dalen, Love and Lorenzen, Eline D. and Marques-Bonet, Tomas and Hansen, Anders J. and Zhang, Guojie and Bhak, Jong and Yamaguchi, Nobuyuki and Gilbert, M. Thomas P.}, title = {Genomic adaptations and evolutionary history of the extinct scimitar-toothed cat}, series = {Current biology}, volume = {30}, journal = {Current biology}, number = {24}, publisher = {Cell Press}, address = {Cambridge}, issn = {0960-9822}, doi = {10.1016/j.cub.2020.09.051}, pages = {14}, year = {2020}, abstract = {Homotherium was a genus of large-bodied scimitar-toothed cats, morphologically distinct from any extant felid species, that went extinct at the end of the Pleistocene [1-4]. They possessed large, saber-form serrated canine teeth, powerful forelimbs, a sloping back, and an enlarged optic bulb, all of which were key characteristics for predation on Pleistocene megafauna [5]. Previous mitochondrial DNA phylogenies suggested that it was a highly divergent sister lineage to all extant cat species [6-8]. However, mitochondrial phylogenies can be misled by hybridization [9], incomplete lineage sorting (ILS), or sex-biased dispersal patterns [10], which might be especially relevant for Homotherium since widespread mito-nuclear discrepancies have been uncovered in modern cats [10]. To examine the evolutionary history of Homotherium, we generated a -7x nuclear genome and a similar to 38x exome from H. latidens using shotgun and target-capture sequencing approaches. Phylogenetic analyses reveal Homotherium as highly divergent (similar to 22.5 Ma) from living cat species, with no detectable signs of gene flow. Comparative genomic analyses found signatures of positive selection in several genes, including those involved in vision, cognitive function, and energy consumption, putatively consistent with diurnal activity, well-developed social behavior, and cursorial hunting [5]. Finally, we uncover relatively high levels of genetic diversity, suggesting that Homotherium may have been more abundant than the limited fossil record suggests [3, 4, 11-14]. Our findings complement and extend previous inferences from both the fossil record and initial molecular studies, enhancing our understanding of the evolution and ecology of this remarkable lineage.}, language = {en} } @misc{NishikawaZhangChoietal.2012, author = {Nishikawa, K.-I. and Zhang, B. and Choi, E. J. and Min, K. W. and Niemiec, J. and Medvedev, M. and Hardee, P. and Mizuno, Y. and Nordlund, A. and Frederiksen, J. and Sol, H. and Pohl, Martin and Hartmann, D. H. and Fishman, G.J.}, title = {Radiation from accelerated particles in shocks}, series = {Postprints der Universit{\"a}t Potsdam : Mathematisch Naturwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch Naturwissenschaftliche Reihe}, number = {600}, issn = {1866-8372}, doi = {10.25932/publishup-41312}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-413128}, pages = {371 -- 372}, year = {2012}, abstract = {Recent PIC simulations of relativistic electron-positron (electron-ion) jets injected into a stationary medium show that particle acceleration occurs in the shocked regions. Simulations show that the Weibel instability is responsible for generating and amplifying highly nonuniform, small-scale magnetic fields and for particle acceleration. These magnetic fields contribute to the electron's transverse eflection behind the shock. The "jitter" radiation from deflected electrons in turbulent magnetic fields has properties different from synchrotron radiation calculated in a uniform magnetic field. This jitter radiation may be important for understanding the complex time evolution and/or spectral structure of gamma-ray bursts, relativistic jets in general, and supernova remnants. In order to calculate radiation from first principles and go beyond the standard synchrotron model, we have used PIC simulations. We present synthetic spectra to compare with the spectra obtained from Fermi observations.}, language = {en} } @article{StruckAndermannHoviusetal.2015, author = {Struck, Martin and Andermann, Christoff and Hovius, Niels and Korup, Oliver and Turowski, Jens M. and Bista, Raj and Pandit, Hari P. and Dahal, Ranjan K.}, title = {Monsoonal hillslope processes determine grain size-specific suspended sediment fluxes in a trans-Himalayan river}, series = {Geophysical research letters}, volume = {42}, journal = {Geophysical research letters}, number = {7}, publisher = {American Geophysical Union}, address = {Washington}, issn = {0094-8276}, doi = {10.1002/2015GL063360}, pages = {2302 -- 2308}, year = {2015}, abstract = {Sediments in rivers record the dynamics of erosion processes. While bulk sediment fluxes are easily and routinely obtained, sediment caliber remains underexplored when inferring erosion mechanisms. Yet sediment grain size distributions may be the key to discriminating their origin. We have studied grain size-specific suspended sediment fluxes in the Kali Gandaki, a major trans-Himalayan river. Two strategically located gauging stations enable tracing of sediment caliber on either side of the Himalayan orographic barrier. The data show that fine sediment input into the northern headwaters is persistent, while coarse sediment comes from the High Himalayas during the summer monsoon. A temporally matching landslide inventory similarly indicates the prominence of monsoon-driven hillslope mass wasting. Thus, mechanisms of sediment supply can leave strong traces in the fluvial caliber, which could project well beyond the mountain front and add to the variability of the sedimentary record of orogen erosion.}, language = {en} } @article{SchellenbergReichertHardtetal.2020, author = {Schellenberg, Johannes and Reichert, Jessica and Hardt, Martin and Klingelh{\"o}fer, Ines and Morlock, Gertrud and Schubert, Patrick and Bižić, Mina and Grossart, Hans-Peter and K{\"a}mpfer, Peter and Wilke, Thomas and Glaeser, Stefanie P.}, title = {The bacterial microbiome of the long-term aquarium cultured high-microbial abundance sponge Haliclona cnidata}, series = {Frontiers in Marine Science}, volume = {7}, journal = {Frontiers in Marine Science}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {2296-7745}, doi = {10.3389/fmars.2020.00266}, pages = {20}, year = {2020}, abstract = {Marine sponges host highly diverse but specific bacterial communities that provide essential functions for the sponge holobiont, including antimicrobial defense. Here, we characterized the bacterial microbiome of the marine sponge Haliclona cnidata that has been in culture in an artificial marine aquarium system. We tested the hypotheses (1) that the long-term aquarium cultured sponge H. cnidata is tightly associated with a typical sponge bacterial microbiota and (2) that the symbiotic Bacteria sustain bioactivity under harmful environmental conditions to facilitate holobiont survival by preventing pathogen invasion. Microscopic and phylogenetic analyses of the bacterial microbiota revealed that H. cnidata represents a high microbial abundance (HMA) sponge with a temporally stable bacterial community that significantly shifts with changing aquarium conditions. A 4-week incubation experiment was performed in small closed aquarium systems with antibiotic and/or light exclusion treatments to reduce the total bacterial and photosynthetically active sponge-associated microbiota to a treatment-specific resilient community. While the holobiont was severely affected by the experimental treatment (i.e., bleaching of the sponge, reduced bacterial abundance, shifted bacterial community composition), the biological defense and bacterial community interactions (i.e., quorum sensing activity) remained intact. 16S rRNA gene amplicon sequencing revealed a resilient community of 105 bacterial taxa, which remained in the treated sponges. These 105 taxa accounted for a relative abundance of 72-83\% of the bacterial sponge microbiota of non-treated sponge fragments that have been cultured under the same conditions. We conclude that a sponge-specific resilient community stays biologically active under harmful environmental conditions, facilitating the resilience of the holobiont. In H. cnidata, bacteria are located in bacteriocytes, which may have contributed to the observed phenomenon.}, language = {en} } @article{MartinNideverBeslaetal.2015, author = {Martin, Nicolas F. and Nidever, David L. and Besla, Gurtina and Olsen, Knut and Walker, Alistair R. and Vivas, A. Katherina and Gruendl, Robert A. and Kaleida, Catherine C. and Munoz, Ricardo R. and Blum, Robert D. and Saha, Abhijit and Conn, Blair C. and Bell, Eric F. and Chu, You-Hua and Cioni, Maria-Rosa L. and de Boer, Thomas J. L. and Gallart, Carme and Jin, Shoko and Kunder, Andrea and Majewski, Steven R. and Martinez-Delgado, David and Monachesi, Antonela and Monelli, Matteo and Monteagudo, Lara and Noel, Noelia E. D. and Olszewski, Edward W. and Stringfellow, Guy S. and van der Marel, Roeland P. and Zaritsky, Dennis}, title = {Hydra II: A faint and compact milky way dwarf galaxy found in the survey of the magellanic stellar history}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters}, volume = {804}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters}, number = {1}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {2041-8205}, doi = {10.1088/2041-8205/804/1/L5}, pages = {6}, year = {2015}, abstract = {We present the discovery of a new dwarf galaxy, Hydra II, found serendipitously within the data from the ongoing Survey of the Magellanic Stellar History conducted with the Dark Energy Camera on the Blanco 4 m Telescope. The new satellite is compact (r(h) = 68 +/- 11 pc) and faint (MV = -4.8 +/- 0.3), but well within the realm of dwarf galaxies. The stellar distribution of Hydra II in the color-magnitude diagram is well-described by a metal-poor ([Fe/H] = -2.2) and old (13 Gyr) isochrone and shows a distinct blue horizontal branch, some possible red clump stars, and faint stars that are suggestive of blue stragglers. At a heliocentric distance of 134 +/- 10 kpc, Hydra II is located in a region of the Galactic halo that models have suggested may host material from the leading arm of the Magellanic Stream. A comparison with N-body simulations hints that the new dwarf galaxy could be or could have been a satellite of the Magellanic Clouds.}, language = {en} } @article{MartinJungbluthNideveretal.2016, author = {Martin, Nicolas F. and Jungbluth, Valentin and Nidever, David L. and Bell, Eric F. and Besla, Gurtina and Blum, Robert D. and Cioni, Maria-Rosa L. and Conn, Blair C. and Kaleida, Catherine C. and Gallart, Carme and Jin, Shoko and Majewski, Steven R. and Martinez-Delgado, David and Monachesi, Antonela and Munoz, Ricardo R. and Noel, Noelia E. D. and Olsen, Knut and Stringfellow, Guy S. and van der Marel, Roeland P. and Vivas, A. Katherina and Walker, Alistair R. and Zaritsky, Dennis}, title = {SMASH 1: A VERY FAINT GLOBULAR CLUSTER DISRUPTING IN THE OUTER REACHES OF THE LMC?}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters}, volume = {830}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {2041-8205}, doi = {10.3847/2041-8205/830/1/L10}, pages = {92 -- 98}, year = {2016}, language = {en} } @article{OranWeissSantacruzPichetal.2022, author = {Oran, Rona and Weiss, Benjamin P. and Santacruz-Pich, Maria De Soria and Jun, Insoo and Lawrence, David J. and Polanskey, Carol A. and Ratliff, J. Martin and Raymond, Carol A. and Ream, Jodie B. and Russell, Christopher T. and Shprits, Yuri Y. and Zuber, Maria T. and Elkins-Tanton, Linda T.}, title = {Maximum energies of trapped particles around magnetized planets and small bodies}, series = {Geophysical research letters}, volume = {49}, journal = {Geophysical research letters}, number = {13}, publisher = {American Geophysical Union}, address = {Washington}, issn = {0094-8276}, doi = {10.1029/2021GL097014}, pages = {11}, year = {2022}, abstract = {Energetic charged particles trapped in planetary radiation belts are hazardous to spacecraft. Planned missions to iron-rich asteroids with possible strong remanent magnetic fields require an assessment of trapped particles energies. Using laboratory measurements of iron meteorites, we estimate the largest possible asteroid magnetic moment. Although weak compared to moments of planetary dynamos, the small body size may yield strong surface fields. We use hybrid simulations to confirm the formation of a magnetosphere with an extended quasi-dipolar region. However, the short length scale of the field implies that energetic particle motion would be nonadiabatic, making existing radiation belt theories not applicable. Our idealized particle simulations demonstrate that chaotic motions lead to particle loss at lower energies than those predicted by adiabatic theory, which may explain the energies of transiently trapped particles observed at Mercury, Ganymede, and Earth. However, even the most magnetized asteroids are unlikely to stably trap hazardous particles.}, language = {en} } @misc{GorskiJungLietal.2020, author = {Gorski, Mathias and Jung, Bettina and Li, Yong and Matias-Garcia, Pamela R. and Wuttke, Matthias and Coassin, Stefan and Thio, Chris H. L. and Kleber, Marcus E. and Winkler, Thomas W. and Wanner, Veronika and Chai, Jin-Fang and Chu, Audrey Y. and Cocca, Massimiliano and Feitosa, Mary F. and Ghasemi, Sahar and Hoppmann, Anselm and Horn, Katrin and Li, Man and Nutile, Teresa and Scholz, Markus and Sieber, Karsten B. and Teumer, Alexander and Tin, Adrienne and Wang, Judy and Tayo, Bamidele O. and Ahluwalia, Tarunveer S. and Almgren, Peter and Bakker, Stephan J. L. and Banas, Bernhard and Bansal, Nisha and Biggs, Mary L. and Boerwinkle, Eric and B{\"o}ttinger, Erwin and Brenner, Hermann and Carroll, Robert J. and Chalmers, John and Chee, Miao-Li and Chee, Miao-Ling and Cheng, Ching-Yu and Coresh, Josef and de Borst, Martin H. and Degenhardt, Frauke and Eckardt, Kai-Uwe and Endlich, Karlhans and Franke, Andre and Freitag-Wolf, Sandra and Gampawar, Piyush and Gansevoort, Ron T. and Ghanbari, Mohsen and Gieger, Christian and Hamet, Pavel and Ho, Kevin and Hofer, Edith and Holleczek, Bernd and Foo, Valencia Hui Xian and Hutri-Kahonen, Nina and Hwang, Shih-Jen and Ikram, M. Arfan and Josyula, Navya Shilpa and Kahonen, Mika and Khor, Chiea-Chuen and Koenig, Wolfgang and Kramer, Holly and Kraemer, Bernhard K. and Kuehnel, Brigitte and Lange, Leslie A. and Lehtimaki, Terho and Lieb, Wolfgang and Loos, Ruth J. F. and Lukas, Mary Ann and Lyytikainen, Leo-Pekka and Meisinger, Christa and Meitinger, Thomas and Melander, Olle and Milaneschi, Yuri and Mishra, Pashupati P. and Mononen, Nina and Mychaleckyj, Josyf C. and Nadkarni, Girish N. and Nauck, Matthias and Nikus, Kjell and Ning, Boting and Nolte, Ilja M. and O'Donoghue, Michelle L. and Orho-Melander, Marju and Pendergrass, Sarah A. and Penninx, Brenda W. J. H. and Preuss, Michael H. and Psaty, Bruce M. and Raffield, Laura M. and Raitakari, Olli T. and Rettig, Rainer and Rheinberger, Myriam and Rice, Kenneth M. and Rosenkranz, Alexander R. and Rossing, Peter and Rotter, Jerome and Sabanayagam, Charumathi and Schmidt, Helena and Schmidt, Reinhold and Schoettker, Ben and Schulz, Christina-Alexandra and Sedaghat, Sanaz and Shaffer, Christian M. and Strauch, Konstantin and Szymczak, Silke and Taylor, Kent D. and Tremblay, Johanne and Chaker, Layal and van der Harst, Pim and van der Most, Peter J. and Verweij, Niek and Voelker, Uwe and Waldenberger, Melanie and Wallentin, Lars and Waterworth, Dawn M. and White, Harvey D. and Wilson, James G. and Wong, Tien-Yin and Woodward, Mark and Yang, Qiong and Yasuda, Masayuki and Yerges-Armstrong, Laura M. and Zhang, Yan and Snieder, Harold and Wanner, Christoph and Boger, Carsten A. and Kottgen, Anna and Kronenberg, Florian and Pattaro, Cristian and Heid, Iris M.}, title = {Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline}, series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Reihe der Digital Engineering Fakult{\"a}t}, journal = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Reihe der Digital Engineering Fakult{\"a}t}, number = {19}, doi = {10.25932/publishup-56537}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-565379}, pages = {14}, year = {2020}, abstract = {Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25\% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95\% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function.}, language = {en} } @article{GorskiJungLietal.2020, author = {Gorski, Mathias and Jung, Bettina and Li, Yong and Matias-Garcia, Pamela R. and Wuttke, Matthias and Coassin, Stefan and Thio, Chris H. L. and Kleber, Marcus E. and Winkler, Thomas W. and Wanner, Veronika and Chai, Jin-Fang and Chu, Audrey Y. and Cocca, Massimiliano and Feitosa, Mary F. and Ghasemi, Sahar and Hoppmann, Anselm and Horn, Katrin and Li, Man and Nutile, Teresa and Scholz, Markus and Sieber, Karsten B. and Teumer, Alexander and Tin, Adrienne and Wang, Judy and Tayo, Bamidele O. and Ahluwalia, Tarunveer S. and Almgren, Peter and Bakker, Stephan J. L. and Banas, Bernhard and Bansal, Nisha and Biggs, Mary L. and Boerwinkle, Eric and B{\"o}ttinger, Erwin and Brenner, Hermann and Carroll, Robert J. and Chalmers, John and Chee, Miao-Li and Chee, Miao-Ling and Cheng, Ching-Yu and Coresh, Josef and de Borst, Martin H. and Degenhardt, Frauke and Eckardt, Kai-Uwe and Endlich, Karlhans and Franke, Andre and Freitag-Wolf, Sandra and Gampawar, Piyush and Gansevoort, Ron T. and Ghanbari, Mohsen and Gieger, Christian and Hamet, Pavel and Ho, Kevin and Hofer, Edith and Holleczek, Bernd and Foo, Valencia Hui Xian and Hutri-Kahonen, Nina and Hwang, Shih-Jen and Ikram, M. Arfan and Josyula, Navya Shilpa and Kahonen, Mika and Khor, Chiea-Chuen and Koenig, Wolfgang and Kramer, Holly and Kraemer, Bernhard K. and Kuehnel, Brigitte and Lange, Leslie A. and Lehtimaki, Terho and Lieb, Wolfgang and Loos, Ruth J. F. and Lukas, Mary Ann and Lyytikainen, Leo-Pekka and Meisinger, Christa and Meitinger, Thomas and Melander, Olle and Milaneschi, Yuri and Mishra, Pashupati P. and Mononen, Nina and Mychaleckyj, Josyf C. and Nadkarni, Girish N. and Nauck, Matthias and Nikus, Kjell and Ning, Boting and Nolte, Ilja M. and O'Donoghue, Michelle L. and Orho-Melander, Marju and Pendergrass, Sarah A. and Penninx, Brenda W. J. H. and Preuss, Michael H. and Psaty, Bruce M. and Raffield, Laura M. and Raitakari, Olli T. and Rettig, Rainer and Rheinberger, Myriam and Rice, Kenneth M. and Rosenkranz, Alexander R. and Rossing, Peter and Rotter, Jerome and Sabanayagam, Charumathi and Schmidt, Helena and Schmidt, Reinhold and Schoettker, Ben and Schulz, Christina-Alexandra and Sedaghat, Sanaz and Shaffer, Christian M. and Strauch, Konstantin and Szymczak, Silke and Taylor, Kent D. and Tremblay, Johanne and Chaker, Layal and van der Harst, Pim and van der Most, Peter J. and Verweij, Niek and Voelker, Uwe and Waldenberger, Melanie and Wallentin, Lars and Waterworth, Dawn M. and White, Harvey D. and Wilson, James G. and Wong, Tien-Yin and Woodward, Mark and Yang, Qiong and Yasuda, Masayuki and Yerges-Armstrong, Laura M. and Zhang, Yan and Snieder, Harold and Wanner, Christoph and Boger, Carsten A. and Kottgen, Anna and Kronenberg, Florian and Pattaro, Cristian and Heid, Iris M.}, title = {Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline}, series = {Kidney international : official journal of the International Society of Nephrology}, volume = {99}, journal = {Kidney international : official journal of the International Society of Nephrology}, number = {4}, publisher = {Elsevier}, address = {New York}, organization = {Lifelines Cohort Study
Regeneron Genetics Ctr}, issn = {0085-2538}, doi = {10.1016/j.kint.2020.09.030}, pages = {926 -- 939}, year = {2020}, abstract = {Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25\% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95\% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function.}, language = {en} } @misc{FinchBrakerReindletal.2019, author = {Finch, Nicolle L. and Braker, I. P. and Reindl, Nicole and Barstow, Martin A. and Casewell, Sarah L. and Burleigh, M. and Kupfer, Thomas and Kilkenny, D. and Geier, Stephan and Schaffenroth, Veronika and Bertolami Miller, Marcelo Miguel and Taubenberger, Stefan and Freudenthal, Joseph}, title = {Spectral Analysis of Binary Pre-white Dwarf Systems}, series = {Radiative signatures from the cosmos}, volume = {519}, journal = {Radiative signatures from the cosmos}, publisher = {Astronomical soc pacific}, address = {San Fransisco}, isbn = {978-1-58381-925-8}, issn = {1050-3390}, pages = {231 -- 238}, year = {2019}, abstract = {Short period double degenerate white dwarf (WD) binaries with periods of less than similar to 1 day are considered to be one of the likely progenitors of type Ia supernovae. These binaries have undergone a period of common envelope evolution. If the core ignites helium before the envelope is ejected, then a hot subdwarf remains prior to contracting into a WD. Here we present a comparison of two very rare systems that contain two hot subdwarfs in short period orbits. We provide a quantitative spectroscopic analysis of the systems using synthetic spectra from state-of-the-art non-LTE models to constrain the atmospheric parameters of the stars. We also use these models to determine the radial velocities, and thus calculate dynamical masses for the stars in each system.}, language = {en} } @article{BurattiThomasRoussosetal.2019, author = {Buratti, Bonnie J. and Thomas, P. C. and Roussos, Elias and Howett, Carly and Seiss, Martin and Hendrix, A. R. and Helfenstein, Paul and Brown, R. H. and Clark, R. N. and Denk, Tilmann and Filacchione, Gianrico and Hoffmann, Holger and Jones, Geraint H. and Khawaja, N. and Kollmann, Peter and Krupp, Norbert and Lunine, Jonathan and Momary, T. W. and Paranicas, Christopher and Postberg, Frank and Sachse, Manuel and Spahn, Frank and Spencer, John and Srama, Ralf and Albin, T. and Baines, K. H. and Ciarniello, Mauro and Economou, Thanasis and Hsu, Hsiang-Wen and Kempf, Sascha and Krimigis, Stamatios M. and Mitchell, Donald and Moragas-Klostermeyer, Georg and Nicholson, Philip D. and Porco, C. C. and Rosenberg, Heike and Simolka, Jonas and Soderblom, Laurence A.}, title = {Close Cassini flybys of Saturn's ring moons Pan, Daphnis, Atlas, Pandora, and Epimetheus}, series = {Science}, volume = {364}, journal = {Science}, number = {6445}, publisher = {American Assoc. for the Advancement of Science}, address = {Washington}, issn = {0036-8075}, doi = {10.1126/science.aat2349}, pages = {1053}, year = {2019}, abstract = {Saturn's main ring system is associated with a set of small moons that either are embedded within it or interact with the rings to alter their shape and composition. Five close flybys of the moons Pan, Daphnis, Atlas, Pandora, and Epimetheus were performed between December 2016 and April 2017 during the ring-grazing orbits of the Cassini mission. Data on the moons' morphology, structure, particle environment, and composition were returned, along with images in the ultraviolet and thermal infrared. We find that the optical properties of the moons' surfaces are determined by two competing processes: contamination by a red material formed in Saturn's main ring system and accretion of bright icy particles or water vapor from volcanic plumes originating on the moon Enceladus.}, language = {en} } @article{LorenzHochheimerTozeretal.1995, author = {Lorenz, Bernd and Hochheimer, H. D. and Tozer, S. W. and Menon, V. and Parthasarathy, R. and Martin, C. R. and Hor, P.-H.}, title = {High pressure low temperature investigation of template synthesized conducting polymers}, year = {1995}, language = {en} } @article{SunHenniesPietzschetal.2011, author = {Sun, Y. -P. and Hennies, Franz and Pietzsch, Annette and Kennedy, B. and Schmitt, Thorsten and Strocov, Vladimir N. and Andersson, Joakim and Berglund, Martin and Rubensson, Jan-Erik and Aidas, K. and Gel'mukhanov, F. and Odelius, Michael and F{\"o}hlisch, Alexander}, title = {Intramolecular soft modes and intermolecular interactions in liquid acetone}, series = {Physical review : B, Condensed matter and materials physics}, volume = {84}, journal = {Physical review : B, Condensed matter and materials physics}, number = {13}, publisher = {American Physical Society}, address = {College Park}, issn = {1098-0121}, doi = {10.1103/PhysRevB.84.132202}, pages = {4}, year = {2011}, abstract = {Resonant inelastic x-ray scattering spectra excited at the O1s(-1)pi* resonance of liquid acetone are presented. Scattering to the electronic ground state shows a resolved vibrational progression where the dominant contribution is due to the C-O stretching mode, thus demonstrating a unique sensitivity of the method to the local potential energy surface in complex molecular systems. For scattering to electronically excited states, soft vibrational modes and, to a smaller extent, intermolecular interactions give a broadening, which blurs the vibrational fine structure. It is predicted that environmental broadening is dominant in aqueous acetone.}, language = {en} }