@article{AartsAndersonAndersonetal.2015, author = {Aarts, Alexander A. and Anderson, Joanna E. and Anderson, Christopher J. and Attridge, Peter R. and Attwood, Angela and Axt, Jordan and Babel, Molly and Bahnik, Stepan and Baranski, Erica and Barnett-Cowan, Michael and Bartmess, Elizabeth and Beer, Jennifer and Bell, Raoul and Bentley, Heather and Beyan, Leah and Binion, Grace and Borsboom, Denny and Bosch, Annick and Bosco, Frank A. and Bowman, Sara D. and Brandt, Mark J. and Braswell, Erin and Brohmer, Hilmar and Brown, Benjamin T. and Brown, Kristina and Bruening, Jovita and Calhoun-Sauls, Ann and Callahan, Shannon P. and Chagnon, Elizabeth and Chandler, Jesse and Chartier, Christopher R. and Cheung, Felix and Christopherson, Cody D. and Cillessen, Linda and Clay, Russ and Cleary, Hayley and Cloud, Mark D. and Cohn, Michael and Cohoon, Johanna and Columbus, Simon and Cordes, Andreas and Costantini, Giulio and Alvarez, Leslie D. Cramblet and Cremata, Ed and Crusius, Jan and DeCoster, Jamie and DeGaetano, Michelle A. and Della Penna, Nicolas and den Bezemer, Bobby and Deserno, Marie K. and Devitt, Olivia and Dewitte, Laura and Dobolyi, David G. and Dodson, Geneva T. and Donnellan, M. Brent and Donohue, Ryan and Dore, Rebecca A. and Dorrough, Angela and Dreber, Anna and Dugas, Michelle and Dunn, Elizabeth W. and Easey, Kayleigh and Eboigbe, Sylvia and Eggleston, Casey and Embley, Jo and Epskamp, Sacha and Errington, Timothy M. and Estel, Vivien and Farach, Frank J. and Feather, Jenelle and Fedor, Anna and Fernandez-Castilla, Belen and Fiedler, Susann and Field, James G. and Fitneva, Stanka A. and Flagan, Taru and Forest, Amanda L. and Forsell, Eskil and Foster, Joshua D. and Frank, Michael C. and Frazier, Rebecca S. and Fuchs, Heather and Gable, Philip and Galak, Jeff and Galliani, Elisa Maria and Gampa, Anup and Garcia, Sara and Gazarian, Douglas and Gilbert, Elizabeth and Giner-Sorolla, Roger and Gl{\"o}ckner, Andreas and G{\"o}llner, Lars and Goh, Jin X. and Goldberg, Rebecca and Goodbourn, Patrick T. and Gordon-McKeon, Shauna and Gorges, Bryan and Gorges, Jessie and Goss, Justin and Graham, Jesse and Grange, James A. and Gray, Jeremy and Hartgerink, Chris and Hartshorne, Joshua and Hasselman, Fred and Hayes, Timothy and Heikensten, Emma and Henninger, Felix and Hodsoll, John and Holubar, Taylor and Hoogendoorn, Gea and Humphries, Denise J. and Hung, Cathy O. -Y. and Immelman, Nathali and Irsik, Vanessa C. and Jahn, Georg and Jaekel, Frank and Jekel, Marc and Johannesson, Magnus and Johnson, Larissa G. and Johnson, David J. and Johnson, Kate M. and Johnston, William J. and Jonas, Kai and Joy-Gaba, Jennifer A. and Kappes, Heather Barry and Kelso, Kim and Kidwell, Mallory C. and Kim, Seung Kyung and Kirkhart, Matthew and Kleinberg, Bennett and Knezevic, Goran and Kolorz, Franziska Maria and Kossakowski, Jolanda J. and Krause, Robert Wilhelm and Krijnen, Job and Kuhlmann, Tim and Kunkels, Yoram K. and Kyc, Megan M. and Lai, Calvin K. and Laique, Aamir and Lakens, Daniel and Lane, Kristin A. and Lassetter, Bethany and Lazarevic, Ljiljana B. and LeBel, Etienne P. and Lee, Key Jung and Lee, Minha and Lemm, Kristi and Levitan, Carmel A. and Lewis, Melissa and Lin, Lin and Lin, Stephanie and Lippold, Matthias and Loureiro, Darren and Luteijn, Ilse and Mackinnon, Sean and Mainard, Heather N. and Marigold, Denise C. and Martin, Daniel P. and Martinez, Tylar and Masicampo, E. J. and Matacotta, Josh and Mathur, Maya and May, Michael and Mechin, Nicole and Mehta, Pranjal and Meixner, Johannes and Melinger, Alissa and Miller, Jeremy K. and Miller, Mallorie and Moore, Katherine and M{\"o}schl, Marcus and Motyl, Matt and M{\"u}ller, Stephanie M. and Munafo, Marcus and Neijenhuijs, Koen I. and Nervi, Taylor and Nicolas, Gandalf and Nilsonne, Gustav and Nosek, Brian A. and Nuijten, Michele B. and Olsson, Catherine and Osborne, Colleen and Ostkamp, Lutz and Pavel, Misha and Penton-Voak, Ian S. and Perna, Olivia and Pernet, Cyril and Perugini, Marco and Pipitone, R. Nathan and Pitts, Michael and Plessow, Franziska and Prenoveau, Jason M. and Rahal, Rima-Maria and Ratliff, Kate A. and Reinhard, David and Renkewitz, Frank and Ricker, Ashley A. and Rigney, Anastasia and Rivers, Andrew M. and Roebke, Mark and Rutchick, Abraham M. and Ryan, Robert S. and Sahin, Onur and Saide, Anondah and Sandstrom, Gillian M. and Santos, David and Saxe, Rebecca and Schlegelmilch, Rene and Schmidt, Kathleen and Scholz, Sabine and Seibel, Larissa and Selterman, Dylan Faulkner and Shaki, Samuel and Simpson, William B. and Sinclair, H. Colleen and Skorinko, Jeanine L. M. and Slowik, Agnieszka and Snyder, Joel S. and Soderberg, Courtney and Sonnleitner, Carina and Spencer, Nick and Spies, Jeffrey R. and Steegen, Sara and Stieger, Stefan and Strohminger, Nina and Sullivan, Gavin B. and Talhelm, Thomas and Tapia, Megan and te Dorsthorst, Anniek and Thomae, Manuela and Thomas, Sarah L. and Tio, Pia and Traets, Frits and Tsang, Steve and Tuerlinckx, Francis and Turchan, Paul and Valasek, Milan and Van Aert, Robbie and van Assen, Marcel and van Bork, Riet and van de Ven, Mathijs and van den Bergh, Don and van der Hulst, Marije and van Dooren, Roel and van Doorn, Johnny and van Renswoude, Daan R. and van Rijn, Hedderik and Vanpaemel, Wolf and Echeverria, Alejandro Vasquez and Vazquez, Melissa and Velez, Natalia and Vermue, Marieke and Verschoor, Mark and Vianello, Michelangelo and Voracek, Martin and Vuu, Gina and Wagenmakers, Eric-Jan and Weerdmeester, Joanneke and Welsh, Ashlee and Westgate, Erin C. and Wissink, Joeri and Wood, Michael and Woods, Andy and Wright, Emily and Wu, Sining and Zeelenberg, Marcel and Zuni, Kellylynn}, title = {Estimating the reproducibility of psychological science}, series = {Science}, volume = {349}, journal = {Science}, number = {6251}, publisher = {American Assoc. for the Advancement of Science}, address = {Washington}, organization = {Open Sci Collaboration}, issn = {1095-9203}, doi = {10.1126/science.aac4716}, pages = {8}, year = {2015}, abstract = {Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available. Replication effects were half the magnitude of original effects, representing a substantial decline. Ninety-seven percent of original studies had statistically significant results. Thirty-six percent of replications had statistically significant results; 47\% of original effect sizes were in the 95\% confidence interval of the replication effect size; 39\% of effects were subjectively rated to have replicated the original result; and if no bias in original results is assumed, combining original and replication results left 68\% with statistically significant effects. Correlational tests suggest that replication success was better predicted by the strength of original evidence than by characteristics of the original and replication teams.}, language = {en} } @article{WuttkeLiLietal.2019, author = {Wuttke, Matthias and Li, Yong and Li, Man and Sieber, Karsten B. and Feitosa, Mary F. and Gorski, Mathias and Tin, Adrienne and Wang, Lihua and Chu, Audrey Y. and Hoppmann, Anselm and Kirsten, Holger and Giri, Ayush and Chai, Jin-Fang and Sveinbjornsson, Gardar and Tayo, Bamidele O. and Nutile, Teresa and Fuchsberger, Christian and Marten, Jonathan and Cocca, Massimiliano and Ghasemi, Sahar and Xu, Yizhe and Horn, Katrin and Noce, Damia and Van der Most, Peter J. and Sedaghat, Sanaz and Yu, Zhi and Akiyama, Masato and Afaq, Saima and Ahluwalia, Tarunveer Singh and Almgren, Peter and Amin, Najaf and Arnlov, Johan and Bakker, Stephan J. L. and Bansal, Nisha and Baptista, Daniela and Bergmann, Sven and Biggs, Mary L. and Biino, Ginevra and Boehnke, Michael and Boerwinkle, Eric and Boissel, Mathilde and B{\"o}ttinger, Erwin and Boutin, Thibaud S. and Brenner, Hermann and Brumat, Marco and Burkhardt, Ralph and Butterworth, Adam S. and Campana, Eric and Campbell, Archie and Campbell, Harry and Canouil, Mickael and Carroll, Robert J. and Catamo, Eulalia and Chambers, John C. and Chee, Miao-Ling and Chee, Miao-Li and Chen, Xu and Cheng, Ching-Yu and Cheng, Yurong and Christensen, Kaare and Cifkova, Renata and Ciullo, Marina and Concas, Maria Pina and Cook, James P. and Coresh, Josef and Corre, Tanguy and Sala, Cinzia Felicita and Cusi, Daniele and Danesh, John and Daw, E. Warwick and De Borst, Martin H. and De Grandi, Alessandro and De Mutsert, Renee and De Vries, Aiko P. J. and Degenhardt, Frauke and Delgado, Graciela and Demirkan, Ayse and Di Angelantonio, Emanuele and Dittrich, Katalin and Divers, Jasmin and Dorajoo, Rajkumar and Eckardt, Kai-Uwe and Ehret, Georg and Elliott, Paul and Endlich, Karlhans and Evans, Michele K. and Felix, Janine F. and Foo, Valencia Hui Xian and Franco, Oscar H. and Franke, Andre and Freedman, Barry I. and Freitag-Wolf, Sandra and Friedlander, Yechiel and Froguel, Philippe and Gansevoort, Ron T. and Gao, He and Gasparini, Paolo and Gaziano, J. Michael and Giedraitis, Vilmantas and Gieger, Christian and Girotto, Giorgia and Giulianini, Franco and Gogele, Martin and Gordon, Scott D. and Gudbjartsson, Daniel F. and Gudnason, Vilmundur and Haller, Toomas and Hamet, Pavel and Harris, Tamara B. and Hartman, Catharina A. and Hayward, Caroline and Hellwege, Jacklyn N. and Heng, Chew-Kiat and Hicks, Andrew A. and Hofer, Edith and Huang, Wei and Hutri-Kahonen, Nina and Hwang, Shih-Jen and Ikram, M. Arfan and Indridason, Olafur S. and Ingelsson, Erik and Ising, Marcus and Jaddoe, Vincent W. V. and Jakobsdottir, Johanna and Jonas, Jost B. and Joshi, Peter K. and Josyula, Navya Shilpa and Jung, Bettina and Kahonen, Mika and Kamatani, Yoichiro and Kammerer, Candace M. and Kanai, Masahiro and Kastarinen, Mika and Kerr, Shona M. and Khor, Chiea-Chuen and Kiess, Wieland and Kleber, Marcus E. and Koenig, Wolfgang and Kooner, Jaspal S. and Korner, Antje and Kovacs, Peter and Kraja, Aldi T. and Krajcoviechova, Alena and Kramer, Holly and Kramer, Bernhard K. and Kronenberg, Florian and Kubo, Michiaki and Kuhnel, Brigitte and Kuokkanen, Mikko and Kuusisto, Johanna and La Bianca, Martina and Laakso, Markku and Lange, Leslie A. and Langefeld, Carl D. and Lee, Jeannette Jen-Mai and Lehne, Benjamin and Lehtimaki, Terho and Lieb, Wolfgang and Lim, Su-Chi and Lind, Lars and Lindgren, Cecilia M. and Liu, Jun and Liu, Jianjun and Loeffler, Markus and Loos, Ruth J. F. and Lucae, Susanne and Lukas, Mary Ann and Lyytikainen, Leo-Pekka and Magi, Reedik and Magnusson, Patrik K. E. and Mahajan, Anubha and Martin, Nicholas G. and Martins, Jade and Marz, Winfried and Mascalzoni, Deborah and Matsuda, Koichi and Meisinger, Christa and Meitinger, Thomas and Melander, Olle and Metspalu, Andres and Mikaelsdottir, Evgenia K. and Milaneschi, Yuri and Miliku, Kozeta and Mishra, Pashupati P. and Program, V. A. Million Veteran and Mohlke, Karen L. and Mononen, Nina and Montgomery, Grant W. and Mook-Kanamori, Dennis O. and Mychaleckyj, Josyf C. and Nadkarni, Girish N. and Nalls, Mike A. and Nauck, Matthias and Nikus, Kjell and Ning, Boting and Nolte, Ilja M. and Noordam, Raymond and Olafsson, Isleifur and Oldehinkel, Albertine J. and Orho-Melander, Marju and Ouwehand, Willem H. and Padmanabhan, Sandosh and Palmer, Nicholette D. and Palsson, Runolfur and Penninx, Brenda W. J. H. and Perls, Thomas and Perola, Markus and Pirastu, Mario and Pirastu, Nicola and Pistis, Giorgio and Podgornaia, Anna I. and Polasek, Ozren and Ponte, Belen and Porteous, David J. and Poulain, Tanja and Pramstaller, Peter P. and Preuss, Michael H. and Prins, Bram P. and Province, Michael A. and Rabelink, Ton J. and Raffield, Laura M. and Raitakari, Olli T. and Reilly, Dermot F. and Rettig, Rainer and Rheinberger, Myriam and Rice, Kenneth M. and Ridker, Paul M. and Rivadeneira, Fernando and Rizzi, Federica and Roberts, David J. and Robino, Antonietta and Rossing, Peter and Rudan, Igor and Rueedi, Rico and Ruggiero, Daniela and Ryan, Kathleen A. and Saba, Yasaman and Sabanayagam, Charumathi and Salomaa, Veikko and Salvi, Erika and Saum, Kai-Uwe and Schmidt, Helena and Schmidt, Reinhold and Ben Schottker, and Schulz, Christina-Alexandra and Schupf, Nicole and Shaffer, Christian M. and Shi, Yuan and Smith, Albert V. and Smith, Blair H. and Soranzo, Nicole and Spracklen, Cassandra N. and Strauch, Konstantin and Stringham, Heather M. and Stumvoll, Michael and Svensson, Per O. and Szymczak, Silke and Tai, E-Shyong and Tajuddin, Salman M. and Tan, Nicholas Y. Q. and Taylor, Kent D. and Teren, Andrej and Tham, Yih-Chung and Thiery, Joachim and Thio, Chris H. L. and Thomsen, Hauke and Thorleifsson, Gudmar and Toniolo, Daniela and Tonjes, Anke and Tremblay, Johanne and Tzoulaki, Ioanna and Uitterlinden, Andre G. and Vaccargiu, Simona and Van Dam, Rob M. and Van der Harst, Pim and Van Duijn, Cornelia M. and Edward, Digna R. Velez and Verweij, Niek and Vogelezang, Suzanne and Volker, Uwe and Vollenweider, Peter and Waeber, Gerard and Waldenberger, Melanie and Wallentin, Lars and Wang, Ya Xing and Wang, Chaolong and Waterworth, Dawn M. and Bin Wei, Wen and White, Harvey and Whitfield, John B. and Wild, Sarah H. and Wilson, James F. and Wojczynski, Mary K. and Wong, Charlene and Wong, Tien-Yin and Xu, Liang and Yang, Qiong and Yasuda, Masayuki and Yerges-Armstrong, Laura M. and Zhang, Weihua and Zonderman, Alan B. and Rotter, Jerome I. and Bochud, Murielle and Psaty, Bruce M. and Vitart, Veronique and Wilson, James G. and Dehghan, Abbas and Parsa, Afshin and Chasman, Daniel I. and Ho, Kevin and Morris, Andrew P. and Devuyst, Olivier and Akilesh, Shreeram and Pendergrass, Sarah A. and Sim, Xueling and Boger, Carsten A. and Okada, Yukinori and Edwards, Todd L. and Snieder, Harold and Stefansson, Kari and Hung, Adriana M. and Heid, Iris M. and Scholz, Markus and Teumer, Alexander and Kottgen, Anna and Pattaro, Cristian}, title = {A catalog of genetic loci associated with kidney function from analyses of a million individuals}, series = {Nature genetics}, volume = {51}, journal = {Nature genetics}, number = {6}, publisher = {Nature Publ. Group}, address = {New York}, organization = {Lifelines COHort Study}, issn = {1061-4036}, doi = {10.1038/s41588-019-0407-x}, pages = {957 -- +}, year = {2019}, abstract = {Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic complications. Through transancestry meta-analysis of genome-wide association studies of estimated glomerular filtration rate (eGFR) and independent replication (n = 1,046,070), we identified 264 associated loci (166 new). Of these,147 were likely to be relevant for kidney function on the basis of associations with the alternative kidney function marker blood urea nitrogen (n = 416,178). Pathway and enrichment analyses, including mouse models with renal phenotypes, support the kidney as the main target organ. A genetic risk score for lower eGFR was associated with clinically diagnosed CKD in 452,264 independent individuals. Colocalization analyses of associations with eGFR among 783,978 European-ancestry individuals and gene expression across 46 human tissues, including tubulo-interstitial and glomerular kidney compartments, identified 17 genes differentially expressed in kidney. Fine-mapping highlighted missense driver variants in 11 genes and kidney-specific regulatory variants. These results provide a comprehensive priority list of molecular targets for translational research.}, language = {en} } @article{AbdoAckermannAjelloetal.2011, author = {Abdo, A. A. and Ackermann, Margit and Ajello, M. and Allafort, A. J. and Baldini, L. and Ballet, J. and Barbiellini, G. and Baring, M. G. and Bastieri, D. and Bechtol, K. C. and Bellazzini, R. and Berenji, B. and Blandford, R. D. and Bloom, E. D. and Bonamente, E. and Borgland, A. W. and Bouvier, A. and Brandt, T. J. and Bregeon, Johan and Brez, A. and Brigida, M. and Bruel, P. and Buehler, R. and Buson, S. and Caliandro, G. A. and Cameron, R. 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H. and Bugaev, V. and Cannon, A. and Cesarini, A. and Ciupik, L. and Cui, W. and Dickherber, R. and Errando, M. and Falcone, A. and Finley, J. P. and Finnegan, G. and Fortson, L. and Furniss, A. and Galante, N. and Gall, D. and Gillanders, G. H. and Godambe, S. and Grube, J. and Guenette, R. and Gyuk, G. and Hanna, D. and Holder, J. and Huang, D. and Hui, C. M. and Humensky, T. B. and Kaaret, P. and Karlsson, N. and Kertzman, M. and Kieda, D. and Konopelko, A. and Krawczynski, H. and Krennrich, F. and Lang, M. J. and Maier, G. and McArthur, S. and McCann, A. and McCutcheon, M. and Moriarty, P. and Mukherjee, R. and Ong, R. and Otte, N. and Pandel, D. and Perkins, J. S. and Pichel, A. and Pohl, M. and Quinn, J. and Ragan, K. and Reyes, L. C. and Reynolds, P. T. and Roache, E. and Rose, H. J. and Rovero, A. C. and Schroedter, M. and Sembroski, G. H. and Senturk, G. D. and Steele, D. and Swordy, S. P. and Tesic, G. and Theiling, M. and Thibadeau, S. and Varlotta, A. and Vincent, S. and Wakely, S. P. and Ward, J. E. and Weekes, T. C. and Weinstein, A. and Weisgarber, T. and Williams, D. A. and Wood, M. and Zitzer, B. and Villata, M. and Raiteri, C. M. and Aller, H. D. and Aller, M. F. and Arkharov, A. A. and Blinov, D. A. and Calcidese, P. and Chen, W. P. and Efimova, N. V. and Kimeridze, G. and Konstantinova, T. S. and Kopatskaya, E. N. and Koptelova, E. and Kurtanidze, O. M. and Kurtanidze, S. O. and Lahteenmaki, A. and Larionov, V. M. and Larionova, E. G. and Larionova, L. V. and Ligustri, R. and Morozova, D. A. and Nikolashvili, M. G. and Sigua, L. A. and Troitsky, I. S. and Angelakis, E. and Capalbi, M. and Carraminana, A. and Carrasco, L. and Cassaro, P. and de la Fuente, E. and Gurwell, M. A. and Kovalev, Y. Y. and Kovalev, Yu. A. and Krichbaum, T. P. and Krimm, H. A. and Leto, Paolo and Lister, M. L. and Maccaferri, G. and Moody, J. W. and Mori, Y. and Nestoras, I. and Orlati, A. and Pagani, C. and Pace, C. and Pearson, R. and Perri, M. and Piner, B. G. and Pushkarev, A. B. and Ros, E. and Sadun, A. C. and Sakamoto, T. and Tornikoski, M. and Yatsu, Y. and Zook, A.}, title = {Insights into the high-energy gamma-Ray emission of markarian 501 fromextensive multifrequency observations in the fermi era}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, volume = {727}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, number = {2}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, organization = {Fermi-LAT Collaboration, MAGIC Collaboration, VERITAS Collaboration}, issn = {0004-637X}, doi = {10.1088/0004-637X/727/2/129}, pages = {26}, year = {2011}, abstract = {We report on the gamma-ray activity of the blazar Mrk 501 during the first 480 days of Fermi operation. We find that the average Large Area Telescope (LAT) gamma-ray spectrum of Mrk 501 can be well described by a single power-law function with a photon index of 1.78 +/- 0.03. While we observe relatively mild flux variations with the Fermi-LAT (within less than a factor of two), we detect remarkable spectral variability where the hardest observed spectral index within the LAT energy range is 1.52 +/- 0.14, and the softest one is 2.51 +/- 0.20. These unexpected spectral changes do not correlate with the measured flux variations above 0.3 GeV. In this paper, we also present the first results from the 4.5 month long multifrequency campaign (2009 March 15-August 1) on Mrk 501, which included the Very Long Baseline Array (VLBA), Swift, RXTE, MAGIC, and VERITAS, the F-GAMMA, GASP-WEBT, and other collaborations and instruments which provided excellent temporal and energy coverage of the source throughout the entire campaign. The extensive radio to TeV data set from this campaign provides us with the most detailed spectral energy distribution yet collected for this source during its relatively low activity. The average spectral energy distribution of Mrk 501 is well described by the standard one-zone synchrotron self-Compton (SSC) model. In the framework of this model, we find that the dominant emission region is characterized by a size less than or similar to 0.1 pc (comparable within a factor of few to the size of the partially resolved VLBA core at 15-43 GHz), and that the total jet power (similar or equal to 10(44) erg s(-1)) constitutes only a small fraction (similar to 10(-3)) of the Eddington luminosity. The energy distribution of the freshly accelerated radiating electrons required to fit the time-averaged data has a broken power-law form in the energy range 0.3 GeV-10 TeV, with spectral indices 2.2 and 2.7 below and above the break energy of 20 GeV. We argue that such a form is consistent with a scenario in which the bulk of the energy dissipation within the dominant emission zone of Mrk 501 is due to relativistic, proton-mediated shocks. We find that the ultrarelativistic electrons and mildly relativistic protons within the blazar zone, if comparable in number, are in approximate energy equipartition, with their energy dominating the jet magnetic field energy by about two orders of magnitude.}, language = {en} } @article{AbramowskiAceroAharonianetal.2012, author = {Abramowski, Attila and Acero, F. and Aharonian, Felix A. and Akhperjanian, A. G. and Anton, Gisela and Balzer, Arnim and Barnacka, Anna and de Almeida, U. Barres and Becherini, Yvonne and Becker, J. and Behera, B. and Bernl{\"o}hr, K. and Birsin, E. and Biteau, Jonathan and Bochow, A. and Boisson, Catherine and Bolmont, J. and Bordas, Pol and Brucker, J. and Brun, Francois and Brun, Pierre and Bulik, Tomasz and Buesching, I. and Carrigan, Svenja and Casanova, Sabrina and Cerruti, M. and Chadwick, Paula M. and Charbonnier, A. and Chaves, Ryan C. G. and Cheesebrough, A. and Clapson, A. C. and Coignet, G. and Cologna, Gabriele and Conrad, Jan and Dalton, M. and Daniel, M. K. and Davids, I. D. and Degrange, B. and Deil, C. and Dickinson, H. J. and Djannati-Ata{\"i}, A. and Domainko, W. and Drury, L. O'C. and Dubus, G. and Dutson, K. and Dyks, J. and Dyrda, M. and Egberts, Kathrin and Eger, P. and Espigat, P. and Fallon, L. and Farnier, C. and Fegan, S. and Feinstein, F. and Fernandes, M. V. and Fiasson, A. and Fontaine, G. and Foerster, A. and Fuessling, M. and Gallant, Y. A. and Gast, H. and Gerard, L. and Gerbig, D. and Giebels, B. and Glicenstein, J. F. and Glueck, B. and Goret, P. and Goering, D. and Haeffner, S. and Hague, J. D. and Hampf, D. and Hauser, M. and Heinz, S. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hinton, James Anthony and Hoffmann, A. and Hofmann, W. and Hofverberg, P. and Holler, M. and Horns, D. and Jacholkowska, A. and de Jager, O. C. and Jahn, C. and Jamrozy, M. and Jung, I. and Kastendieck, M. A. and Katarzynski, K. and Katz, U. and Kaufmann, S. and Keogh, D. and Khangulyan, D. and Khelifi, B. and Klochkov, D. and Kluzniak, W. and Kneiske, T. and Komin, Nu. and Kosack, K. and Kossakowski, R. and Laffon, H. and Lamanna, G. and Lennarz, D. and Lohse, T. and Lopatin, A. and Lu, C. -C. and Marandon, V. and Marcowith, Alexandre and Masbou, J. and Maurin, D. and Maxted, N. and Mayer, M. and McComb, T. J. L. and Medina, M. C. and Mehault, J. and Moderski, R. and Moulin, Emmanuel and Naumann, C. L. and Naumann-Godo, M. and de Naurois, M. and Nedbal, D. and Nekrassov, D. and Nguyen, N. and Nicholas, B. and Niemiec, J. and Nolan, S. J. and Ohm, S. and Wilhelmi, E. de Ona and Opitz, B. and Ostrowski, M. and Oya, I. and Panter, M. and Arribas, M. Paz and Pedaletti, G. and Pelletier, G. and Petrucci, P. -O. and Pita, S. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raue, M. and Rayner, S. M. and Reimer, A. and Reimer, O. and Renaud, M. and de los Reyes, R. and Rieger, F. and Ripken, J. and Rob, L. and Rosier-Lees, S. and Rowell, G. and Rudak, B. and Rulten, C. B. and Ruppel, J. and Sahakian, V. and Sanchez, David M. and Santangelo, A. and Schlickeiser, R. and Schoeck, F. M. and Schulz, A. and Schwanke, U. and Schwarzburg, S. and Schwemmer, S. and Sheidaei, F. and Skilton, J. L. and Sol, H. and Spengler, G. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stinzing, F. and Stycz, K. and Sushch, Iurii and Szostek, A. and Tavernet, J. -P. and Terrier, R. and Tluczykont, M. and Valerius, K. and van Eldik, C. and Vasileiadis, G. and Venter, C. and Vialle, J. P. and Viana, A. and Vincent, P. and Voelk, H. J. and Volpe, F. and Vorobiov, S. and Vorster, M. and Wagner, S. J. and Ward, M. and White, R. and Wierzcholska, A. and Zacharias, M. and Zajczyk, A. and Zdziarski, A. A. and Zech, Alraune and Zechlin, H. -S. and Aleksic, J. and Antonelli, L. A. and Antoranz, P. and Backes, Michael and Barrio, J. A. and Bastieri, D. and Becerra Gonzalez, J. and Bednarek, W. and Berdyugin, A. and Berger, K. and Bernardini, E. and Biland, A. and Blanch Bigas, O. and Bock, R. K. and Boller, A. and Bonnoli, G. and Tridon, D. Borla and Braun, I. and Bretz, T. and Canellas, A. and Carmona, E. and Carosi, A. and Colin, P. and Colombo, E. and Contreras, J. L. and Cortina, J. and Cossio, L. and Covino, S. and Dazzi, F. and De Angelis, A. and De Cea del Pozo, E. and De Lotto, B. and Delgado Mendez, C. and Diago Ortega, A. and Doert, M. and Dominguez, A. and Prester, Dijana Dominis and Dorner, D. and Doro, M. and Elsaesser, D. and Ferenc, D. and Fonseca, M. V. and Font, L. and Fruck, C. and Garcia Lopez, R. J. and Garczarczyk, M. and Garrido, D. and Giavitto, G. and Godinovic, N. and Hadasch, D. and Haefner, D. and Herrero, A. and Hildebrand, D. and Hoehne-Moench, D. and Hose, J. and Hrupec, D. and Huber, B. and Jogler, T. and Klepser, S. and Kraehenbuehl, T. and Krause, J. and La Barbera, A. and Lelas, D. and Leonardo, E. and Lindfors, E. and Lombardi, S. and Lopez, M. and Lorenz, E. and Makariev, M. and Maneva, G. and Mankuzhiyil, N. and Mannheim, K. and Maraschi, L. and Mariotti, M. and Martinez, M. and Mazin, D. and Meucci, M. and Miranda, J. M. and Mirzoyan, R. and Miyamoto, H. and Moldon, J. and Moralejo, A. and Munar, P. and Nieto, D. and Nilsson, K. and Orito, R. and Oya, I. and Paneque, D. and Paoletti, R. and Pardo, S. and Paredes, J. M. and Partini, S. and Pasanen, M. and Pauss, F. and Perez-Torres, M. A. and Persic, M. and Peruzzo, L. and Pilia, M. and Pochon, J. and Prada, F. and Moroni, P. G. Prada and Prandini, E. and Puljak, I. and Reichardt, I. and Reinthal, R. and Rhode, W. and Ribo, M. and Rico, J. and Ruegamer, S. and Saggion, A. and Saito, K. and Saito, T. Y. and Salvati, M. and Satalecka, K. and Scalzotto, V. and Scapin, V. and Schultz, C. and Schweizer, T. and Shayduk, M. and Shore, S. N. and Sillanpaa, A. and Sitarek, J. and Sobczynska, D. and Spanier, F. and Spiro, S. and Stamerra, A. and Steinke, B. and Storz, J. and Strah, N. and Suric, T. and Takalo, L. and Takami, H. and Tavecchio, F. and Temnikov, P. and Terzic, T. and Tescaro, D. and Teshima, M. and Thom, M. and Tibolla, O. and Torres, D. F. and Treves, A. and Vankov, H. and Vogler, P. and Wagner, R. M. and Weitzel, Q. and Zabalza, V. and Zandanel, F. and Zanin, R. and Arlen, T. and Aune, T. and Beilicke, M. and Benbow, W. and Bouvier, A. and Bradbury, S. M. and Buckley, J. H. and Bugaev, V. and Byrum, K. and Cannon, A. and Cesarini, A. and Ciupik, L. and Connolly, M. P. and Cui, W. and Dickherber, R. and Duke, C. and Errando, M. and Falcone, A. and Finley, J. P. and Finnegan, G. and Fortson, L. and Furniss, A. and Galante, N. and Gall, D. and Godambe, S. and Griffin, S. and Grube, J. and Gyuk, G. and Hanna, D. and Holder, J. and Huan, H. and Hui, C. M. and Kaaret, P. and Karlsson, N. and Kertzman, M. and Khassen, Y. and Kieda, D. and Krawczynski, H. and Krennrich, F. and Lang, M. J. and LeBohec, S. and Maier, G. and McArthur, S. and McCann, A. and Moriarty, P. and Mukherjee, R. and Nunez, P. D. and Ong, R. A. and Orr, M. and Otte, A. N. and Park, N. and Perkins, J. S. and Pichel, A. and Pohl, Martin and Prokoph, H. and Ragan, K. and Reyes, L. C. and Reynolds, P. T. and Roache, E. and Rose, H. J. and Ruppel, J. and Schroedter, M. and Sembroski, G. H. and Sentuerk, G. D. and Telezhinsky, Igor O. and Tesic, G. and Theiling, M. and Thibadeau, S. and Varlotta, A. and Vassiliev, V. V. and Vivier, M. and Wakely, S. P. and Weekes, T. C. and Williams, D. A. and Zitzer, B. and de Almeida, U. Barres and Cara, M. and Casadio, C. and Cheung, C. C. and McConville, W. and Davies, F. and Doi, A. and Giovannini, G. and Giroletti, M. and Hada, K. and Hardee, P. and Harris, D. E. and Junor, W. and Kino, M. and Lee, N. P. and Ly, C. and Madrid, J. and Massaro, F. and Mundell, C. G. and Nagai, H. and Perlman, E. S. and Steele, I. A. and Walker, R. C. and Wood, D. L.}, title = {The 2010 very high energy gamma-ray flare and 10 years ofmulti-wavelength oservations of M 87}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, volume = {746}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, number = {2}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, organization = {HESS Collaboration, MAGIC Collaboration, VERITAS Collaboration}, issn = {0004-637X}, doi = {10.1088/0004-637X/746/2/151}, pages = {18}, year = {2012}, abstract = {The giant radio galaxy M 87 with its proximity (16 Mpc), famous jet, and very massive black hole ((3-6) x 10(9) M-circle dot) provides a unique opportunity to investigate the origin of very high energy (VHE; E > 100 GeV) gamma-ray emission generated in relativistic outflows and the surroundings of supermassive black holes. M 87 has been established as a VHE gamma-ray emitter since 2006. The VHE gamma-ray emission displays strong variability on timescales as short as a day. In this paper, results from a joint VHE monitoring campaign on M 87 by the MAGIC and VERITAS instruments in 2010 are reported. During the campaign, a flare at VHE was detected triggering further observations at VHE (H.E.S.S.), X-rays (Chandra), and radio (43 GHz Very Long Baseline Array, VLBA). The excellent sampling of the VHE gamma-ray light curve enables one to derive a precise temporal characterization of the flare: the single, isolated flare is well described by a two-sided exponential function with significantly different flux rise and decay times of tau(rise)(d) = (1.69 +/- 0.30) days and tau(decay)(d) = (0.611 +/- 0.080) days, respectively. While the overall variability pattern of the 2010 flare appears somewhat different from that of previous VHE flares in 2005 and 2008, they share very similar timescales (similar to day), peak fluxes (Phi(>0.35 TeV) similar or equal to (1-3) x 10(-11) photons cm(-2) s(-1)), and VHE spectra. VLBA radio observations of 43 GHz of the inner jet regions indicate no enhanced flux in 2010 in contrast to observations in 2008, where an increase of the radio flux of the innermost core regions coincided with a VHE flare. On the other hand, Chandra X-ray observations taken similar to 3 days after the peak of the VHE gamma-ray emission reveal an enhanced flux from the core (flux increased by factor similar to 2; variability timescale <2 days). The long-term (2001-2010) multi-wavelength (MWL) light curve of M 87, spanning from radio to VHE and including data from Hubble Space Telescope, Liverpool Telescope, Very Large Array, and European VLBI Network, is used to further investigate the origin of the VHE gamma-ray emission. No unique, common MWL signature of the three VHE flares has been identified. In the outer kiloparsec jet region, in particular in HST-1, no enhanced MWL activity was detected in 2008 and 2010, disfavoring it as the origin of the VHE flares during these years. Shortly after two of the three flares (2008 and 2010), the X-ray core was observed to be at a higher flux level than its characteristic range (determined from more than 60 monitoring observations: 2002-2009). In 2005, the strong flux dominance of HST-1 could have suppressed the detection of such a feature. Published models for VHE gamma-ray emission from M 87 are reviewed in the light of the new data.}, language = {en} } @article{AceroAloisioAmansetal.2017, author = {Acero, F. and Aloisio, R. and Amans, J. and Amato, Elena and Antonelli, L. A. and Aramo, C. and Armstrong, T. and Arqueros, F. and Asano, Katsuaki and Ashley, M. and Backes, M. and Balazs, C. and Balzer, A. and Bamba, Aya and Barkov, Maxim and Barrio, J. A. and Benbow, Wystan and Bernloehr, K. and Beshley, V. and Bigongiari, C. and Biland, A. and Bilinsky, A. and Bissaldi, Elisabetta and Biteau, J. and Blanch, O. and Blasi, P. and Blazek, J. and Boisson, C. and Bonanno, G. and Bonardi, A. and Bonavolonta, C. and Bonnoli, G. and Braiding, C. and Brau-Nogue, S. and Bregeon, J. and Brown, A. M. and Bugaev, V. and Bulgarelli, A. and Bulik, T. and Burton, Michael and Burtovoi, A. and Busetto, G. and Bottcher, M. and Cameron, R. and Capalbi, M. and Caproni, Anderson and Caraveo, P. and Carosi, R. and Cascone, E. and Cerruti, M. and Chaty, Sylvain and Chen, A. and Chen, X. and Chernyakova, M. and Chikawa, M. and Chudoba, J. and Cohen-Tanugi, J. and Colafrancesco, S. and Conforti, V. and Contreras, J. L. and Costa, A. and Cotter, G. and Covino, Stefano and Covone, G. and Cumani, P. and Cusumano, G. and Daniel, M. and Dazzi, F. and De Angelis, A. and De Cesare, G. and De Franco, A. and De Frondat, F. and Dal Pino, E. M. de Gouveia and De Lisio, C. and Lopez, R. de los Reyes and De Lotto, B. and de Naurois, M. and De Palma, F. and Del Santo, M. and Delgado, C. and della Volpe, D. and Di Girolamo, T. and Di Giulio, C. and Di Pierro, F. and Di Venere, L. and Doro, M. and Dournaux, J. and Dumas, D. and Dwarkadas, Vikram V. and Diaz, C. and Ebr, J. and Egberts, Kathrin and Einecke, S. and Elsaesser, D. and Eschbach, S. and Falceta-Goncalves, D. and Fasola, G. and Fedorova, E. and Fernandez-Barral, A. and Ferrand, Gilles and Fesquet, M. and Fiandrini, E. and Fiasson, A. and Filipovic, Miroslav D. and Fioretti, V. and Font, L. and Fontaine, Gilles and Franco, F. J. and Freixas Coromina, L. and Fujita, Yutaka and Fukui, Y. and Funk, S. and Forster, A. and Gadola, A. and Lopez, R. Garcia and Garczarczyk, M. and Giglietto, N. and Giordano, F. and Giuliani, A. and Glicenstein, J. and Gnatyk, R. and Goldoni, P. and Grabarczyk, T. and Graciani, R. and Graham, J. and Grandi, P. and Granot, Jonathan and Green, A. J. and Griffiths, S. and Gunji, S. and Hakobyan, H. and Hara, S. and Hassan, T. and Hayashida, M. and Heller, M. and Helo, J. C. and Hinton, J. and Hnatyk, B. and Huet, J. and Huetten, M. and Humensky, T. B. and Hussein, M. and Horandel, J. and Ikeno, Y. and Inada, T. and Inome, Y. and Inoue, S. and Inoue, T. and Inoue, Y. and Ioka, K. and Iori, Maurizio and Jacquemier, J. and Janecek, P. and Jankowsky, D. and Jung, I. and Kaaret, P. and Katagiri, H. and Kimeswenger, S. and Kimura, Shigeo S. and Knodlseder, J. and Koch, B. and Kocot, J. and Kohri, K. and Komin, N. and Konno, Y. and Kosack, K. and Koyama, S. and Kraus, Michaela and Kubo, Hidetoshi and Mezek, G. Kukec and Kushida, J. and La Palombara, N. and Lalik, K. and Lamanna, G. and Landt, H. and Lapington, J. and Laporte, P. and Lee, S. and Lees, J. and Lefaucheur, J. and Lenain, J. -P. and Leto, Giuseppe and Lindfors, E. and Lohse, T. and Lombardi, S. and Longo, F. and Lopez, M. and Lucarelli, F. and Luque-Escamilla, Pedro Luis and Lopez-Coto, R. and Maccarone, M. C. and Maier, G. and Malaguti, G. and Mandat, D. and Maneva, G. and Mangano, S. and Marcowith, Alexandre and Marti, J. and Martinez, M. and Martinez, G. and Masuda, S. and Maurin, G. and Maxted, N. and Melioli, Claudio and Mineo, T. and Mirabal, N. and Mizuno, T. and Moderski, R. and Mohammed, M. and Montaruli, T. and Moralejo, A. and Mori, K. and Morlino, G. and Morselli, A. and Moulin, Emmanuel and Mukherjee, R. and Mundell, C. and Muraishi, H. and Murase, Kohta and Nagataki, Shigehiro and Nagayoshi, T. and Naito, T. and Nakajima, D. and Nakamori, T. and Nemmen, R. and Niemiec, Jacek and Nieto, D. and Nievas-Rosillo, M. and Nikolajuk, M. and Nishijima, K. and Noda, K. and Nogues, L. and Nosek, D. and Novosyadlyj, B. and Nozaki, S. and Ohira, Yutaka and Ohishi, M. and Ohm, S. and Okumura, A. and Ong, R. A. and Orito, R. and Orlati, A. and Ostrowski, M. and Oya, I. and Padovani, Marco and Palacio, J. and Palatka, M. and Paredes, Josep M. and Pavy, S. and Persic, M. and Petrucci, P. and Petruk, Oleh and Pisarski, A. and Pohl, Martin and Porcelli, A. and Prandini, E. and Prast, J. and Principe, G. and Prouza, M. and Pueschel, Elisa and Puelhofer, G. and Quirrenbach, A. and Rameez, M. and Reimer, O. and Renaud, M. and Ribo, M. and Rico, J. and Rizi, V. and Rodriguez, J. and Fernandez, G. Rodriguez and Rodriguez Vazquez, J. J. and Romano, Patrizia and Romeo, G. and Rosado, J. and Rousselle, J. and Rowell, G. and Rudak, B. and Sadeh, I. and Safi-Harb, S. and Saito, T. and Sakaki, N. and Sanchez, D. and Sangiorgi, P. and Sano, H. and Santander, M. and Sarkar, S. and Sawada, M. and Schioppa, E. J. and Schoorlemmer, H. and Schovanek, P. and Schussler, F. and Sergijenko, O. and Servillat, M. and Shalchi, A. and Shellard, R. C. and Siejkowski, H. and Sillanpaa, A. and Simone, D. and Sliusar, V. and Sol, H. and Stanic, S. and Starling, R. and Stawarz, L. and Stefanik, S. and Stephan, M. and Stolarczyk, T. and Szanecki, M. and Szepieniec, T. and Tagliaferri, G. and Tajima, H. and Takahashi, M. and Takeda, J. and Tanaka, M. and Tanaka, S. and Tejedor, L. A. and Telezhinsky, Igor O. and Temnikov, P. and Terada, Y. and Tescaro, D. and Teshima, M. and Testa, V. and Thoudam, S. and Tokanai, F. and Torres, D. F. and Torresi, E. and Tosti, G. and Townsley, C. and Travnicek, P. and Trichard, C. and Trifoglio, M. and Tsujimoto, S. and Vagelli, V. and Vallania, P. and Valore, L. and van Driel, W. and van Eldik, C. and Vandenbroucke, Justin and Vassiliev, V. and Vecchi, M. and Vercellone, Stefano and Vergani, S. and Vigorito, C. and Vorobiov, S. and Vrastil, M. and Vazquez Acosta, M. L. and Wagner, S. J. and Wagner, R. and Wakely, S. P. and Walter, R. and Ward, J. E. and Watson, J. J. and Weinstein, A. and White, M. and White, R. and Wierzcholska, A. and Wilcox, P. and Williams, D. A. and Wischnewski, R. and Wojcik, P. and Yamamoto, T. and Yamamoto, H. and Yamazaki, Ryo and Yanagita, S. and Yang, L. and Yoshida, T. and Yoshida, M. and Yoshiike, S. and Yoshikoshi, T. and Zacharias, M. and Zampieri, L. and Zanin, R. and Zavrtanik, M. and Zavrtanik, D. and Zdziarski, A. and Zech, Alraune and Zechlin, Hannes and Zhdanov, V. and Ziegler, A. and Zorn, J.}, title = {Prospects for Cherenkov Telescope Array Observations of the Young Supernova Remnant RX J1713.7-3946}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, volume = {840}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, number = {2}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {0004-637X}, doi = {10.3847/1538-4357/aa6d67}, pages = {14}, year = {2017}, abstract = {We perform simulations for future Cherenkov Telescope Array (CTA) observations of RX J1713.7-3946, a young supernova remnant (SNR) and one of the brightest sources ever discovered in very high energy (VHE) gamma rays. Special attention is paid to exploring possible spatial (anti) correlations of gamma rays with emission at other wavelengths, in particular X-rays and CO/H I emission. We present a series of simulated images of RX J1713.7-3946 for CTA based on a set of observationally motivated models for the gamma-ray emission. In these models, VHE gamma rays produced by high-energy electrons are assumed to trace the nonthermal X-ray emission observed by XMM-Newton, whereas those originating from relativistic protons delineate the local gas distributions. The local atomic and molecular gas distributions are deduced by the NANTEN team from CO and H I observations. Our primary goal is to show how one can distinguish the emission mechanism(s) of the gamma rays (i.e., hadronic versus leptonic, or a mixture of the two) through information provided by their spatial distribution, spectra, and time variation. This work is the first attempt to quantitatively evaluate the capabilities of CTA to achieve various proposed scientific goals by observing this important cosmic particle accelerator.}, language = {en} } @article{ChipmanFerrierBrenaetal.2014, author = {Chipman, Ariel D. and Ferrier, David E. K. and Brena, Carlo and Qu, Jiaxin and Hughes, Daniel S. T. and Schroeder, Reinhard and Torres-Oliva, Montserrat and Znassi, Nadia and Jiang, Huaiyang and Almeida, Francisca C. and Alonso, Claudio R. and Apostolou, Zivkos and Aqrawi, Peshtewani and Arthur, Wallace and Barna, Jennifer C. J. and Blankenburg, Kerstin P. and Brites, Daniela and Capella-Gutierrez, Salvador and Coyle, Marcus and Dearden, Peter K. and Du Pasquier, Louis and Duncan, Elizabeth J. and Ebert, Dieter and Eibner, Cornelius and Erikson, Galina and Evans, Peter D. and Extavour, Cassandra G. and Francisco, Liezl and Gabaldon, Toni and Gillis, William J. and Goodwin-Horn, Elizabeth A. and Green, Jack E. and Griffiths-Jones, Sam and Grimmelikhuijzen, Cornelis J. P. and Gubbala, Sai and Guigo, Roderic and Han, Yi and Hauser, Frank and Havlak, Paul and Hayden, Luke and Helbing, Sophie and Holder, Michael and Hui, Jerome H. L. and Hunn, Julia P. and Hunnekuhl, Vera S. and Jackson, LaRonda and Javaid, Mehwish and Jhangiani, Shalini N. and Jiggins, Francis M. and Jones, Tamsin E. and Kaiser, Tobias S. and Kalra, Divya and Kenny, Nathan J. and Korchina, Viktoriya and Kovar, Christie L. and Kraus, F. Bernhard and Lapraz, Francois and Lee, Sandra L. and Lv, Jie and Mandapat, Christigale and Manning, Gerard and Mariotti, Marco and Mata, Robert and Mathew, Tittu and Neumann, Tobias and Newsham, Irene and Ngo, Dinh N. and Ninova, Maria and Okwuonu, Geoffrey and Ongeri, Fiona and Palmer, William J. and Patil, Shobha and Patraquim, Pedro and Pham, Christopher and Pu, Ling-Ling and Putman, Nicholas H. and Rabouille, Catherine and Ramos, Olivia Mendivil and Rhodes, Adelaide C. and Robertson, Helen E. and Robertson, Hugh M. and Ronshaugen, Matthew and Rozas, Julio and Saada, Nehad and Sanchez-Gracia, Alejandro and Scherer, Steven E. and Schurko, Andrew M. and Siggens, Kenneth W. and Simmons, DeNard and Stief, Anna and Stolle, Eckart and Telford, Maximilian J. and Tessmar-Raible, Kristin and Thornton, Rebecca and van der Zee, Maurijn and von Haeseler, Arndt and Williams, James M. and Willis, Judith H. and Wu, Yuanqing and Zou, Xiaoyan and Lawson, Daniel and Muzny, Donna M. and Worley, Kim C. and Gibbs, Richard A. and Akam, Michael and Richards, Stephen}, title = {The first myriapod genome sequence reveals conservative arthropod gene content and genome organisation in the centipede Strigamia maritima}, series = {PLoS biology}, volume = {12}, journal = {PLoS biology}, number = {11}, publisher = {PLoS}, address = {San Fransisco}, issn = {1545-7885}, doi = {10.1371/journal.pbio.1002005}, pages = {24}, year = {2014}, abstract = {Myriapods (e. g., centipedes and millipedes) display a simple homonomous body plan relative to other arthropods. All members of the class are terrestrial, but they attained terrestriality independently of insects. Myriapoda is the only arthropod class not represented by a sequenced genome. We present an analysis of the genome of the centipede Strigamia maritima. It retains a compact genome that has undergone less gene loss and shuffling than previously sequenced arthropods, and many orthologues of genes conserved from the bilaterian ancestor that have been lost in insects. Our analysis locates many genes in conserved macro-synteny contexts, and many small-scale examples of gene clustering. We describe several examples where S. maritima shows different solutions from insects to similar problems. The insect olfactory receptor gene family is absent from S. maritima, and olfaction in air is likely effected by expansion of other receptor gene families. For some genes S. maritima has evolved paralogues to generate coding sequence diversity, where insects use alternate splicing. This is most striking for the Dscam gene, which in Drosophila generates more than 100,000 alternate splice forms, but in S. maritima is encoded by over 100 paralogues. We see an intriguing linkage between the absence of any known photosensory proteins in a blind organism and the additional absence of canonical circadian clock genes. The phylogenetic position of myriapods allows us to identify where in arthropod phylogeny several particular molecular mechanisms and traits emerged. For example, we conclude that juvenile hormone signalling evolved with the emergence of the exoskeleton in the arthropods and that RR-1 containing cuticle proteins evolved in the lineage leading to Mandibulata. We also identify when various gene expansions and losses occurred. The genome of S. maritima offers us a unique glimpse into the ancestral arthropod genome, while also displaying many adaptations to its specific life history.}, language = {en} } @article{TiegsCostelloIskenetal.2019, author = {Tiegs, Scott D. and Costello, David M. and Isken, Mark W. and Woodward, Guy and McIntyre, Peter B. and Gessner, Mark O. and Chauvet, Eric and Griffiths, Natalie A. and Flecker, Alex S. and Acuna, Vicenc and Albarino, Ricardo and Allen, Daniel C. and Alonso, Cecilia and Andino, Patricio and Arango, Clay and Aroviita, Jukka and Barbosa, Marcus V. M. and Barmuta, Leon A. and Baxter, Colden V. and Bell, Thomas D. C. and Bellinger, Brent and Boyero, Luz and Brown, Lee E. and Bruder, Andreas and Bruesewitz, Denise A. and Burdon, Francis J. and Callisto, Marcos and Canhoto, Cristina and Capps, Krista A. and Castillo, Maria M. and Clapcott, Joanne and Colas, Fanny and Colon-Gaud, Checo and Cornut, Julien and Crespo-Perez, Veronica and Cross, Wyatt F. and Culp, Joseph M. and Danger, Michael and Dangles, Olivier and de Eyto, Elvira and Derry, Alison M. and Diaz Villanueva, Veronica and Douglas, Michael M. and Elosegi, Arturo and Encalada, Andrea C. and Entrekin, Sally and Espinosa, Rodrigo and Ethaiya, Diana and Ferreira, Veronica and Ferriol, Carmen and Flanagan, Kyla M. and Fleituch, Tadeusz and Shah, Jennifer J. Follstad and Frainer, Andre and Friberg, Nikolai and Frost, Paul C. and Garcia, Erica A. and Lago, Liliana Garcia and Garcia Soto, Pavel Ernesto and Ghate, Sudeep and Giling, Darren P. and Gilmer, Alan and Goncalves, Jose Francisco and Gonzales, Rosario Karina and Graca, Manuel A. S. and Grace, Mike and Grossart, Hans-Peter and Guerold, Francois and Gulis, Vlad and Hepp, Luiz U. and Higgins, Scott and Hishi, Takuo and Huddart, Joseph and Hudson, John and Imberger, Samantha and Iniguez-Armijos, Carlos and Iwata, Tomoya and Janetski, David J. and Jennings, Eleanor and Kirkwood, Andrea E. and Koning, Aaron A. and Kosten, Sarian and Kuehn, Kevin A. and Laudon, Hjalmar and Leavitt, Peter R. and Lemes da Silva, Aurea L. and Leroux, Shawn J. and Leroy, Carri J. and Lisi, Peter J. and MacKenzie, Richard and Marcarelli, Amy M. and Masese, Frank O. and Mckie, Brendan G. and Oliveira Medeiros, Adriana and Meissner, Kristian and Milisa, Marko and Mishra, Shailendra and Miyake, Yo and Moerke, Ashley and Mombrikotb, Shorok and Mooney, Rob and Moulton, Tim and Muotka, Timo and Negishi, Junjiro N. and Neres-Lima, Vinicius and Nieminen, Mika L. and Nimptsch, Jorge and Ondruch, Jakub and Paavola, Riku and Pardo, Isabel and Patrick, Christopher J. and Peeters, Edwin T. H. M. and Pozo, Jesus and Pringle, Catherine and Prussian, Aaron and Quenta, Estefania and Quesada, Antonio and Reid, Brian and Richardson, John S. and Rigosi, Anna and Rincon, Jose and Risnoveanu, Geta and Robinson, Christopher T. and Rodriguez-Gallego, Lorena and Royer, Todd V. and Rusak, James A. and Santamans, Anna C. and Selmeczy, Geza B. and Simiyu, Gelas and Skuja, Agnija and Smykla, Jerzy and Sridhar, Kandikere R. and Sponseller, Ryan and Stoler, Aaron and Swan, Christopher M. and Szlag, David and Teixeira-de Mello, Franco and Tonkin, Jonathan D. and Uusheimo, Sari and Veach, Allison M. and Vilbaste, Sirje and Vought, Lena B. M. and Wang, Chiao-Ping and Webster, Jackson R. and Wilson, Paul B. and Woelfl, Stefan and Xenopoulos, Marguerite A. and Yates, Adam G. and Yoshimura, Chihiro and Yule, Catherine M. and Zhang, Yixin X. and Zwart, Jacob A.}, title = {Global patterns and drivers of ecosystem functioning in rivers and riparian zones}, series = {Science Advances}, volume = {5}, journal = {Science Advances}, number = {1}, publisher = {American Assoc. for the Advancement of Science}, address = {Washington}, issn = {2375-2548}, doi = {10.1126/sciadv.aav0486}, pages = {8}, year = {2019}, abstract = {River ecosystems receive and process vast quantities of terrestrial organic carbon, the fate of which depends strongly on microbial activity. Variation in and controls of processing rates, however, are poorly characterized at the global scale. In response, we used a peer-sourced research network and a highly standardized carbon processing assay to conduct a global-scale field experiment in greater than 1000 river and riparian sites. We found that Earth's biomes have distinct carbon processing signatures. Slow processing is evident across latitudes, whereas rapid rates are restricted to lower latitudes. Both the mean rate and variability decline with latitude, suggesting temperature constraints toward the poles and greater roles for other environmental drivers (e.g., nutrient loading) toward the equator. These results and data set the stage for unprecedented "next-generation biomonitoring" by establishing baselines to help quantify environmental impacts to the functioning of ecosystems at a global scale.}, language = {en} } @article{KoenigAblerAgartzetal.2020, author = {Koenig, Julian and Abler, Birgit and Agartz, Ingrid and akerstedt, Torbjorn and Andreassen, Ole A. and Anthony, Mia and Baer, Karl-Juergen and Bertsch, Katja and Brown, Rebecca C. and Brunner, Romuald and Carnevali, Luca and Critchley, Hugo D. and Cullen, Kathryn R. and de Geus, Eco J. C. and de la Cruz, Feliberto and Dziobek, Isabel and Ferger, Marc D. and Fischer, Hakan and Flor, Herta and Gaebler, Michael and Gianaros, Peter J. and Giummarra, Melita J. and Greening, Steven G. and Guendelman, Simon and Heathers, James A. J. and Herpertz, Sabine C. and Hu, Mandy X. and Jentschke, Sebastian and Kaess, Michael and Kaufmann, Tobias and Klimes-Dougan, Bonnie and Koelsch, Stefan and Krauch, Marlene and Kumral, Deniz and Lamers, Femke and Lee, Tae-Ho and Lekander, Mats and Lin, Feng and Lotze, Martin and Makovac, Elena and Mancini, Matteo and Mancke, Falk and Mansson, Kristoffer N. T. and Manuck, Stephen B. and Mather, Mara and Meeten, Frances and Min, Jungwon and Mueller, Bryon and Muench, Vera and Nees, Frauke and Nga, Lin and Nilsonne, Gustav and Ordonez Acuna, Daniela and Osnes, Berge and Ottaviani, Cristina and Penninx, Brenda W. J. H. and Ponzio, Allison and Poudel, Govinda R. and Reinelt, Janis and Ren, Ping and Sakaki, Michiko and Schumann, Andy and Sorensen, Lin and Specht, Karsten and Straub, Joana and Tamm, Sandra and Thai, Michelle and Thayer, Julian F. and Ubani, Benjamin and van Der Mee, Denise J. and van Velzen, Laura S. and Ventura-Bort, Carlos and Villringer, Arno and Watson, David R. and Wei, Luqing and Wendt, Julia and Schreiner, Melinda Westlund and Westlye, Lars T. and Weymar, Mathias and Winkelmann, Tobias and Wu, Guo-Rong and Yoo, Hyun Joo and Quintana, Daniel S.}, title = {Cortical thickness and resting-state cardiac function across the lifespan}, series = {Psychophysiology : journal of the Society for Psychophysiological Research}, volume = {58}, journal = {Psychophysiology : journal of the Society for Psychophysiological Research}, number = {7}, publisher = {Wiley}, address = {Hoboken}, issn = {0048-5772}, doi = {10.1111/psyp.13688}, pages = {16}, year = {2020}, abstract = {Understanding the association between autonomic nervous system [ANS] function and brain morphology across the lifespan provides important insights into neurovisceral mechanisms underlying health and disease. Resting-state ANS activity, indexed by measures of heart rate [HR] and its variability [HRV] has been associated with brain morphology, particularly cortical thickness [CT]. While findings have been mixed regarding the anatomical distribution and direction of the associations, these inconsistencies may be due to sex and age differences in HR/HRV and CT. Previous studies have been limited by small sample sizes, which impede the assessment of sex differences and aging effects on the association between ANS function and CT. To overcome these limitations, 20 groups worldwide contributed data collected under similar protocols of CT assessment and HR/HRV recording to be pooled in a mega-analysis (N = 1,218 (50.5\% female), mean age 36.7 years (range: 12-87)). Findings suggest a decline in HRV as well as CT with increasing age. CT, particularly in the orbitofrontal cortex, explained additional variance in HRV, beyond the effects of aging. This pattern of results may suggest that the decline in HRV with increasing age is related to a decline in orbitofrontal CT. These effects were independent of sex and specific to HRV; with no significant association between CT and HR. Greater CT across the adult lifespan may be vital for the maintenance of healthy cardiac regulation via the ANS-or greater cardiac vagal activity as indirectly reflected in HRV may slow brain atrophy. Findings reveal an important association between CT and cardiac parasympathetic activity with implications for healthy aging and longevity that should be studied further in longitudinal research.}, language = {en} } @article{BalderjahnLeeSeegebarthetal.2019, author = {Balderjahn, Ingo and Lee, Michael S. W. and Seegebarth, Barbara and Peyer, Mathias}, title = {A sustainable pathway to consumer wellbeing}, series = {The Journal of consumer affairs}, volume = {54}, journal = {The Journal of consumer affairs}, number = {2}, publisher = {Wiley}, address = {Malden, Mass.}, issn = {0022-0078}, doi = {10.1111/joca.12278}, pages = {456 -- 488}, year = {2019}, abstract = {This study investigates the effect of different anticonsumption constructs on consumer wellbeing. The study assumes that people will only lower their level of consumption if doing so does not also lower personal wellbeing. More precisely, this research investigates how specific subtypes of sustainable anticonsumption (e.g., voluntary simplicity, collaborative consumption, and debt-free living) relate to different states of consumer's wellbeing (e.g., financial, psychosocial, and subjective wellbeing). This work also examines whether consumer empowerment can improve personal wellbeing and strengthen the anticonsumption wellbeing relationship. The results show that voluntarily foregoing consumption does not reduce wellbeing and consumer empowerment plays a significant role in supporting sustainable pathways to consumer wellbeing. This study reasons that empowerment improves consumer sovereignty, but may be detrimental for consumers heavily concerned about debt-free living. The present investigation concludes by proposing implications for public and consumer policymakers wishing to promote appropriate sustainable (anticonsumption) pathways to consumer wellbeing.}, language = {en} } @article{BalderjahnSeegebarthLee2021, author = {Balderjahn, Ingo and Seegebarth, Barbara and Lee, Michael S. W.}, title = {Less is more!}, series = {Journal of cleaner production}, volume = {284}, journal = {Journal of cleaner production}, publisher = {Elsevier Science}, address = {Amsterdam}, issn = {0959-6526}, doi = {10.1016/j.jclepro.2020.124802}, pages = {12}, year = {2021}, abstract = {Enhancing consumer satisfaction and well-being is an important objective of companies, retailers and public policy makers. In the current debate on climate change, a consistent theme is that consumers in developed countries must learn to consume less. The present study (based on representative data sets from the US, N = 1,017, and Germany, N = 1030) addresses these issues by using a scenario-based experiment to analyze how satisfied voluntary simplifiers (people who voluntarily abstain from consumption) are with their purchase decisions in the case of a muesli brand. The research question is whether people who follow a sustainable, simple lifestyle are more satisfied with their daily consumption choices than people who have a more consumerist lifestyle. If so, it would be easier for many people to change their lifestyles and consume less. In addition, this scenario experiment manipulates consumer empowerment and decision complexity since both factors are supposed to influence purchase satisfaction. The results are consistent across both countries and indicate that voluntary simplifiers experience a higher level of purchasing satisfaction than non-simplifiers, whereby empowerment and decision complexity play different roles.}, language = {en} }