@article{GrajaGarciaCarrizoJanketal.2018, author = {Graja, Antonia and Garcia-Carrizo, Francisco and Jank, Anne-Marie and Gohlke, Sabrina and Ambrosi, Thomas H. and Jonas, Wenke and Ussar, Siegfried and Kern, Matthias and Sch{\"u}rmann, Annette and Aleksandrova, Krasimira and Bluher, Matthias and Schulz, Tim Julius}, title = {Loss of periostin occurs in aging adipose tissue of mice and its genetic ablation impairs adipose tissue lipid metabolism}, series = {Aging Cell}, volume = {17}, journal = {Aging Cell}, number = {5}, publisher = {Wiley}, address = {Hoboken}, issn = {1474-9718}, doi = {10.1111/acel.12810}, pages = {13}, year = {2018}, abstract = {Remodeling of the extracellular matrix is a key component of the metabolic adaptations of adipose tissue in response to dietary and physiological challenges. Disruption of its integrity is a well-known aspect of adipose tissue dysfunction, for instance, during aging and obesity. Adipocyte regeneration from a tissue-resident pool of mesenchymal stem cells is part of normal tissue homeostasis. Among the pathophysiological consequences of adipogenic stem cell aging, characteristic changes in the secretory phenotype, which includes matrix-modifying proteins, have been described. Here, we show that the expression of the matricellular protein periostin, a component of the extracellular matrix produced and secreted by adipose tissue-resident interstitial cells, is markedly decreased in aged brown and white adipose tissue depots. Using a mouse model, we demonstrate that the adaptation of adipose tissue to adrenergic stimulation and high-fat diet feeding is impaired in animals with systemic ablation of the gene encoding for periostin. Our data suggest that loss of periostin attenuates lipid metabolism in adipose tissue, thus recapitulating one aspect of age-related metabolic dysfunction. In human white adipose tissue, periostin expression showed an unexpected positive correlation with age of study participants. This correlation, however, was no longer evident after adjusting for BMI or plasma lipid and liver function biomarkers. These findings taken together suggest that age-related alterations of the adipose tissue extracellular matrix may contribute to the development of metabolic disease by negatively affecting nutrient homeostasis.}, language = {en} } @phdthesis{Kern2023, author = {Kern, Anne}, title = {Juana Borrero}, series = {Mimesis}, volume = {93}, journal = {Mimesis}, publisher = {De Gruyter}, address = {Berlin}, isbn = {978-3-11-074835-2}, issn = {0178-7489}, doi = {10.1515/9783110748499}, school = {Universit{\"a}t Potsdam}, pages = {XIII, 602}, year = {2023}, abstract = {Juana Borrero y Pierra (1877-1896) war eine der wichtigsten Vertreterinnen des inselkubanischen Modernismo. Gleichwohl ist das Schaffen der schon zu Lebzeiten zum Wunderkind stilisierten Autorin, Dichterin und Malerin wissenschaftlich kaum eingehender untersucht worden. Die Werkstudie schl{\"a}gt einen umfassenden, konsequent {\"a}sthetischen Blick auf das aus Gedichten, poetischer Prosa, literarischen Liebesbriefen, Zeichnungen und Malereien bestehende Gesamtwerk Borreros vor, das im Kern ein Streben nach Ganzheit von Kunst und Leben offenlegt. Dabei werden die Text- und Bildstrategien der K{\"u}nstlerin mit den {\"a}sthetischen, soziohistorischen und biografischen Kontexten verzahnt, wodurch Juana Borreros Stimme als exemplarische Stimme der kubanischen Sp{\"a}tmoderne sowie einer bewegten kubanischen Literatur les- und sichtbar wird.}, language = {de} } @article{KokhanovskyLamareDanneetal.2019, author = {Kokhanovsky, Alexander and Lamare, Maxim and Danne, Olaf and Brockmann, Carsten and Dumont, Marie and Picard, Ghislain and Arnaud, Laurent and Favier, Vincent and Jourdain, Bruno and Le Meur, Emmanuel and Di Mauro, Biagio and Aoki, Teruo and Niwano, Masashi and Rozanov, Vladimir and Korkin, Sergey and Kipfstuhl, Sepp and Freitag, Johannes and Hoerhold, Maria and Zuhr, Alexandra and Vladimirova, Diana and Faber, Anne-Katrine and Steen-Larsen, Hans Christian and Wahl, Sonja and Andersen, Jonas K. and Vandecrux, Baptiste and van As, Dirk and Mankoff, Kenneth D. and Kern, Michael and Zege, Eleonora and Box, Jason E.}, title = {Retrieval of Snow Properties from the Sentinel-3 Ocean and Land Colour Instrument}, series = {Remote sensing}, volume = {11}, journal = {Remote sensing}, number = {19}, publisher = {MDPI}, address = {Basel}, issn = {2072-4292}, doi = {10.3390/rs11192280}, pages = {43}, year = {2019}, abstract = {The Sentinel Application Platform (SNAP) architecture facilitates Earth Observation data processing. In this work, we present results from a new Snow Processor for SNAP. We also describe physical principles behind the developed snow property retrieval technique based on the analysis of Ocean and Land Colour Instrument (OLCI) onboard Sentinel-3A/B measurements over clean and polluted snow fields. Using OLCI spectral reflectance measurements in the range 400-1020 nm, we derived important snow properties such as spectral and broadband albedo, snow specific surface area, snow extent and grain size on a spatial grid of 300 m. The algorithm also incorporated cloud screening and atmospheric correction procedures over snow surfaces. We present validation results using ground measurements from Antarctica, the Greenland ice sheet and the French Alps. We find the spectral albedo retrieved with accuracy of better than 3\% on average, making our retrievals sufficient for a variety of applications. Broadband albedo is retrieved with the average accuracy of about 5\% over snow. Therefore, the uncertainties of satellite retrievals are close to experimental errors of ground measurements. The retrieved surface grain size shows good agreement with ground observations. Snow specific surface area observations are also consistent with our OLCI retrievals. We present snow albedo and grain size mapping over the inland ice sheet of Greenland for areas including dry snow, melted/melting snow and impurity rich bare ice. The algorithm can be applied to OLCI Sentinel-3 measurements providing an opportunity for creation of long-term snow property records essential for climate monitoring and data assimilation studies-especially in the Arctic region, where we face rapid environmental changes including reduction of snow/ice extent and, therefore, planetary albedo.}, language = {en} }