@article{TaalStPourcainThieringetal.2012,
  author    = {Taal, H. Rob and St Pourcain, Beate and Thiering, Elisabeth and Das, Shikta and Mook-Kanamori, Dennis O. and Warrington, Nicole M. and Kaakinen, Marika and Kreiner-Moller, Eskil and Bradfield, Jonathan P. and Freathy, Rachel M. and Geller, Frank and Guxens, Monica and Cousminer, Diana L. and Kerkhof, Marjan and Timpson, Nicholas J. and Ikram, M. Arfan and Beilin, Lawrence J. and Bonnelykke, Klaus and Buxton, Jessica L. and Charoen, Pimphen and Chawes, Bo Lund Krogsgaard and Eriksson, Johan and Evans, David M. and Hofman, Albert and Kemp, John P. and Kim, Cecilia E. and Klopp, Norman and Lahti, Jari and Lye, Stephen J. and McMahon, George and Mentch, Frank D. and Mueller-Nurasyid, Martina and O'Reilly, Paul F. and Prokopenko, Inga and Rivadeneira, Fernando and Steegers, Eric A. P. and Sunyer, Jordi and Tiesler, Carla and Yaghootkar, Hanieh and Breteler, Monique M. B. and Debette, Stephanie and Fornage, Myriam and Gudnason, Vilmundur and Launer, Lenore J. and van der Lugt, Aad and Mosley, Thomas H. and Seshadri, Sudha and Smith, Albert V. and Vernooij, Meike W. and Blakemore, Alexandra I. F. and Chiavacci, Rosetta M. and Feenstra, Bjarke and Fernandez-Banet, Julio and Grant, Struan F. A. and Hartikainen, Anna-Liisa and van der Heijden, Albert J. and Iniguez, Carmen and Lathrop, Mark and McArdle, Wendy L. and Molgaard, Anne and Newnham, John P. and Palmer, Lyle J. and Palotie, Aarno and Pouta, Annneli and Ring, Susan M. and Sovio, Ulla and Standl, Marie and Uitterlinden, Andre G. and Wichmann, H-Erich and Vissing, Nadja Hawwa and DeCarli, Charles and van Duijn, Cornelia M. and McCarthy, Mark I. and Koppelman, Gerard H. and Estivill, Xavier and Hattersley, Andrew T. and Melbye, Mads and Bisgaard, Hans and Pennell, Craig E. and Widen, Elisabeth and Hakonarson, Hakon and Smith, George Davey and Heinrich, Joachim and Jarvelin, Marjo-Riitta and Jaddoe, Vincent W. V. and Adair, Linda S. and Ang, Wei and Atalay, Mustafa and van Beijsterveldt, Toos and Bergen, Nienke and Benke, Kelly and Berry, Diane J. and Bradfield, Jonathan P. and Charoen, Pimphen and Coin, Lachlan and Cousminer, Diana L. and Das, Shikta and Davis, Oliver S. P. and Elliott, Paul and Evans, David M. and Feenstra, Bjarke and Flexeder, Claudia and Frayling, Tim and Freathy, Rachel M. and Gaillard, Romy and Geller, Frank and Groen-Blokhuis, Maria and Goh, Liang-Kee and Guxens, Monica and Haworth, Claire M. A. and Hadley, Dexter and Hebebrand, Johannes and Hinney, Anke and Hirschhorn, Joel N. and Holloway, John W. and Holst, Claus and Hottenga, Jouke Jan and Horikoshi, Momoko and Huikari, Ville and Hypponen, Elina and Iniguez, Carmen and Kaakinen, Marika and Kilpelainen, Tuomas O. and Kirin, Mirna and Kowgier, Matthew and Lakka, Hanna-Maaria and Lange, Leslie A. and Lawlor, Debbie A. and Lehtimaki, Terho and Lewin, Alex and Lindgren, Cecilia and Lindi, Virpi and Maggi, Reedik and Marsh, Julie and Middeldorp, Christel and Millwood, Iona and Mook-Kanamori, Dennis O. and Murray, Jeffrey C. and Nivard, Michel and Nohr, Ellen Aagaard and Ntalla, Ioanna and Oken, Emily and O'Reilly, Paul F. and Palmer, Lyle J. and Panoutsopoulou, Kalliope and Pararajasingham, Jennifer and Prokopenko, Inga and Rodriguez, Alina and Salem, Rany M. and Sebert, Sylvain and Siitonen, Niina and Sovio, Ulla and St Pourcain, Beate and Strachan, David P. and Sunyer, Jordi and Taal, H. Rob and Teo, Yik-Ying and Thiering, Elisabeth and Tiesler, Carla and Uitterlinden, Andre G. and Valcarcel, Beatriz and Warrington, Nicole M. and White, Scott and Willemsen, Gonneke and Yaghootkar, Hanieh and Zeggini, Eleftheria and Boomsma, Dorret I. and Cooper, Cyrus and Estivill, Xavier and Gillman, Matthew and Grant, Struan F. A. and Hakonarson, Hakon and Hattersley, Andrew T. and Heinrich, Joachim and Hocher, Berthold and Jaddoe, Vincent W. V. and Jarvelin, Marjo-Riitta and Lakka, Timo A. and McCarthy, Mark I. and Melbye, Mads and Mohlke, Karen L. and Dedoussis, George V. and Ong, Ken K. and Pearson, Ewan R. and Pennell, Craig E. and Price, Thomas S. and Power, Chris and Raitakari, Olli T. and Saw, Seang-Mei and Scherag, Andre and Simell, Olli and Sorensen, Thorkild I. A. and Timpson, Nicholas J. and Widen, Elisabeth and Wilson, James F. and Ang, Wei and van Beijsterveldt, Toos and Bergen, Nienke and Benke, Kelly and Berry, Diane J. and Bradfield, Jonathan P. and Charoen, Pimphen and Coin, Lachlan and Cousminer, Diana L. and Das, Shikta and Elliott, Paul and Evans, David M. and Frayling, Tim and Freathy, Rachel M. and Gaillard, Romy and Groen-Blokhuis, Maria and Guxens, Monica and Hadley, Dexter and Hottenga, Jouke Jan and Huikari, Ville and Hypponen, Elina and Kaakinen, Marika and Kowgier, Matthew and Lawlor, Debbie A. and Lewin, Alex and Lindgren, Cecilia and Marsh, Julie and Middeldorp, Christel and Millwood, Iona and Mook-Kanamori, Dennis O. and Nivard, Michel and O'Reilly, Paul F. and Palmer, Lyle J. and Prokopenko, Inga and Rodriguez, Alina and Sebert, Sylvain and Sovio, Ulla and St Pourcain, Beate and Standl, Marie and Strachan, David P. and Sunyer, Jordi and Taal, H. Rob and Thiering, Elisabeth and Tiesler, Carla and Uitterlinden, Andre G. and Valcarcel, Beatriz and Warrington, Nicole M. and White, Scott and Willemsen, Gonneke and Yaghootkar, Hanieh and Boomsma, Dorret I. and Estivill, Xavier and Grant, Struan F. A. and Hakonarson, Hakon and Hattersley, Andrew T. and Heinrich, Joachim and Jaddoe, Vincent W. V. and Jarvelin, Marjo-Riitta and McCarthy, Mark I. and Pennell, Craig E. and Power, Chris and Timpson, Nicholas J. and Widen, Elisabeth and Ikram, M. Arfan and Fornage, Myriam and Smith, Albert V. and Seshadri, Sudha and Schmidt, Reinhold and Debette, Stephanie and Vrooman, Henri A. and Sigurdsson, Sigurdur and Ropele, Stefan and Coker, Laura H. and Longstreth, W. T. and Niessen, Wiro J. and DeStefano, Anita L. and Beiser, Alexa and Zijdenbos, Alex P. and Struchalin, Maksim and Jack, Clifford R. and Nalls, Mike A. and Au, Rhoda and Hofman, Albert and Gudnason, Haukur and van der Lugt, Aad and Harris, Tamara B. and Meeks, William M. and Vernooij, Meike W. and van Buchem, Mark A. and Catellier, Diane and Gudnason, Vilmundur and Windham, B. Gwen and Wolf, Philip A. and van Duijn, Cornelia M. and Mosley, Thomas H. and Schmidt, Helena and Launer, Lenore J. and Breteler, Monique M. B. and DeCarli, Charles},
  title     = {Common variants at 12q15 and 12q24 are associated with infant head circumference},
  series = {Nature genetics},
  volume    = {44},
  journal   = {Nature genetics},
  number    = {5},
  publisher = {Nature Publ. Group},
  address   = {New York},
  organization    = {Cohorts Heart Aging Res Genetic Ep, Early Genetics Lifecourse Epidemio, Early Growth Genetics EGG Consorti},
  issn      = {1061-4036},
  doi       = {10.1038/ng.2238},
  pages     = {532 -- +},
  year      = {2012},
  abstract  = {To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth cohorts) and followed up three lead signals in six replication studies (combined N = 19,089). rs7980687 on chromosome 12q24 (P = 8.1 x 10(-9)) and rs1042725 on chromosome 12q15 (P = 2.8 x 10(-10)) were robustly associated with head circumference in infancy. Although these loci have previously been associated with adult height(1), their effects on infant head circumference were largely independent of height (P = 3.8 x 10(-7) for rs7980687 and P = 1.3 x 10(-7) for rs1042725 after adjustment for infant height). A third signal, rs11655470 on chromosome 17q21, showed suggestive evidence of association with head circumference (P = 3.9 x 10(-6)). SNPs correlated to the 17q21 signal have shown genome-wide association with adult intracranial volume(2), Parkinson's disease and other neurodegenerative diseases(3-5), indicating that a common genetic variant in this region might link early brain growth with neurological disease in later life.},
  language  = {en}
}
@article{IkramFornageSmithetal.2012,
  author    = {Ikram, M. Arfan and Fornage, Myriam and Smith, Albert V. and Seshadri, Sudha and Schmidt, Reinhold and Debette, Stephanie and Vrooman, Henri A. and Sigurdsson, Sigurdur and Ropele, Stefan and Taal, H. Rob and Mook-Kanamori, Dennis O. and Coker, Laura H. and Longstreth, W. T. and Niessen, Wiro J. and DeStefano, Anita L. and Beiser, Alexa and Zijdenbos, Alex P. and Struchalin, Maksim and Jack, Clifford R. and Rivadeneira, Fernando and Uitterlinden, Andre G. and Knopman, David S. and Hartikainen, Anna-Liisa and Pennell, Craig E. and Thiering, Elisabeth and Steegers, Eric A. P. and Hakonarson, Hakon and Heinrich, Joachim and Palmer, Lyle J. and Jarvelin, Marjo-Riitta and McCarthy, Mark I. and Grant, Struan F. A. and St Pourcain, Beate and Timpson, Nicholas J. and Smith, George Davey and Sovio, Ulla and Nalls, Mike A. and Au, Rhoda and Hofman, Albert and Gudnason, Haukur and van der Lugt, Aad and Harris, Tamara B. and Meeks, William M. and Vernooij, Meike W. and van Buchem, Mark A. and Catellier, Diane and Jaddoe, Vincent W. V. and Gudnason, Vilmundur and Windham, B. Gwen and Wolf, Philip A. and van Duijn, Cornelia M. and Mosley, Thomas H. and Schmidt, Helena and Launer, Lenore J. and Breteler, Monique M. B. and DeCarli, Charles and Adair, Linda S. and Ang, Wei and Atalay, Mustafa and vanBeijsterveldt, Toos and Bergen, Nienke and Benke, Kelly and Berry, Diane J. and Coin, Lachlan and Davis, Oliver S. P. and Elliott, Paul and Flexeder, Claudia and Frayling, Tim and Gaillard, Romy and Groen-Blokhuis, Maria and Goh, Liang-Kee and Haworth, Claire M. A. and Hadley, Dexter and Hebebrand, Johannes and Hinney, Anke and Hirschhorn, Joel N. and Holloway, John W. and Holst, Claus and Hottenga, Jouke Jan and Horikoshi, Momoko and Huikari, Ville and Hypponen, Elina and Kilpelainen, Tuomas O. and Kirin, Mirna and Kowgier, Matthew and Lakka, Hanna-Maaria and Lange, Leslie A. and Lawlor, Debbie A. and Lehtimaki, Terho and Lewin, Alex and Lindgren, Cecilia and Lindi, Virpi and Maggi, Reedik and Marsh, Julie and Middeldorp, Christel and Millwood, Iona and Murray, Jeffrey C. and Nivard, Michel and Nohr, Ellen Aagaard and Ntalla, Ioanna and Oken, Emily and Panoutsopoulou, Kalliope and Pararajasingham, Jennifer and Rodriguez, Alina and Salem, Rany M. and Sebert, Sylvain and Siitonen, Niina and Strachan, David P. and Teo, Yik-Ying and Valcarcel, Beatriz and Willemsen, Gonneke and Zeggini, Eleftheria and Boomsma, Dorret I. and Cooper, Cyrus and Gillman, Matthew and Hocher, Berthold and Lakka, Timo A. and Mohlke, Karen L. and Dedoussis, George V. and Ong, Ken K. and Pearson, Ewan R. and Price, Thomas S. and Power, Chris and Raitakari, Olli T. and Saw, Seang-Mei and Scherag, Andre and Simell, Olli and Sorensen, Thorkild I. A. and Wilson, James F.},
  title     = {Common variants at 6q22 and 17q21 are associated with intracranial volume},
  series = {Nature genetics},
  volume    = {44},
  journal   = {Nature genetics},
  number    = {5},
  publisher = {Nature Publ. Group},
  address   = {New York},
  organization    = {Early Growth Genetics EGG Consorti, Cohorts Heart Aging Res Genomic Ep},
  issn      = {1061-4036},
  doi       = {10.1038/ng.2245},
  pages     = {539 -- +},
  year      = {2012},
  abstract  = {During aging, intracranial volume remains unchanged and represents maximally attained brain size, while various interacting biological phenomena lead to brain volume loss. Consequently, intracranial volume and brain volume in late life reflect different genetic influences. Our genome-wide association study (GWAS) in 8,175 community-dwelling elderly persons did not reveal any associations at genome-wide significance (P < 5 x 10(-8)) for brain volume. In contrast, intracranial volume was significantly associated with two loci: rs4273712 (P = 3.4 x 10(-11)), a known height-associated locus on chromosome 6q22, and rs9915547 (P = 1.5 x 10(-12)), localized to the inversion on chromosome 17q21. We replicated the associations of these loci with intracranial volume in a separate sample of 1,752 elderly persons (P = 1.1 x 10(-3) for 6q22 and 1.2 x 10(-3) for 17q21). Furthermore, we also found suggestive associations of the 17q21 locus with head circumference in 10,768 children (mean age of 14.5 months). Our data identify two loci associated with head size, with the inversion at 17q21 also likely to be involved in attaining maximal brain size.},
  language  = {en}
}
@article{WuttkeLiLietal.2019,
  author    = {Wuttke, Matthias and Li, Yong and Li, Man and Sieber, Karsten B. and Feitosa, Mary F. and Gorski, Mathias and Tin, Adrienne and Wang, Lihua and Chu, Audrey Y. and Hoppmann, Anselm and Kirsten, Holger and Giri, Ayush and Chai, Jin-Fang and Sveinbjornsson, Gardar and Tayo, Bamidele O. and Nutile, Teresa and Fuchsberger, Christian and Marten, Jonathan and Cocca, Massimiliano and Ghasemi, Sahar and Xu, Yizhe and Horn, Katrin and Noce, Damia and Van der Most, Peter J. and Sedaghat, Sanaz and Yu, Zhi and Akiyama, Masato and Afaq, Saima and Ahluwalia, Tarunveer Singh and Almgren, Peter and Amin, Najaf and Arnlov, Johan and Bakker, Stephan J. L. and Bansal, Nisha and Baptista, Daniela and Bergmann, Sven and Biggs, Mary L. and Biino, Ginevra and Boehnke, Michael and Boerwinkle, Eric and Boissel, Mathilde and B{\"o}ttinger, Erwin and Boutin, Thibaud S. and Brenner, Hermann and Brumat, Marco and Burkhardt, Ralph and Butterworth, Adam S. and Campana, Eric and Campbell, Archie and Campbell, Harry and Canouil, Mickael and Carroll, Robert J. and Catamo, Eulalia and Chambers, John C. and Chee, Miao-Ling and Chee, Miao-Li and Chen, Xu and Cheng, Ching-Yu and Cheng, Yurong and Christensen, Kaare and Cifkova, Renata and Ciullo, Marina and Concas, Maria Pina and Cook, James P. and Coresh, Josef and Corre, Tanguy and Sala, Cinzia Felicita and Cusi, Daniele and Danesh, John and Daw, E. Warwick and De Borst, Martin H. and De Grandi, Alessandro and De Mutsert, Renee and De Vries, Aiko P. J. and Degenhardt, Frauke and Delgado, Graciela and Demirkan, Ayse and Di Angelantonio, Emanuele and Dittrich, Katalin and Divers, Jasmin and Dorajoo, Rajkumar and Eckardt, Kai-Uwe and Ehret, Georg and Elliott, Paul and Endlich, Karlhans and Evans, Michele K. and Felix, Janine F. and Foo, Valencia Hui Xian and Franco, Oscar H. and Franke, Andre and Freedman, Barry I. and Freitag-Wolf, Sandra and Friedlander, Yechiel and Froguel, Philippe and Gansevoort, Ron T. and Gao, He and Gasparini, Paolo and Gaziano, J. Michael and Giedraitis, Vilmantas and Gieger, Christian and Girotto, Giorgia and Giulianini, Franco and Gogele, Martin and Gordon, Scott D. and Gudbjartsson, Daniel F. and Gudnason, Vilmundur and Haller, Toomas and Hamet, Pavel and Harris, Tamara B. and Hartman, Catharina A. and Hayward, Caroline and Hellwege, Jacklyn N. and Heng, Chew-Kiat and Hicks, Andrew A. and Hofer, Edith and Huang, Wei and Hutri-Kahonen, Nina and Hwang, Shih-Jen and Ikram, M. Arfan and Indridason, Olafur S. and Ingelsson, Erik and Ising, Marcus and Jaddoe, Vincent W. V. and Jakobsdottir, Johanna and Jonas, Jost B. and Joshi, Peter K. and Josyula, Navya Shilpa and Jung, Bettina and Kahonen, Mika and Kamatani, Yoichiro and Kammerer, Candace M. and Kanai, Masahiro and Kastarinen, Mika and Kerr, Shona M. and Khor, Chiea-Chuen and Kiess, Wieland and Kleber, Marcus E. and Koenig, Wolfgang and Kooner, Jaspal S. and Korner, Antje and Kovacs, Peter and Kraja, Aldi T. and Krajcoviechova, Alena and Kramer, Holly and Kramer, Bernhard K. and Kronenberg, Florian and Kubo, Michiaki and Kuhnel, Brigitte and Kuokkanen, Mikko and Kuusisto, Johanna and La Bianca, Martina and Laakso, Markku and Lange, Leslie A. and Langefeld, Carl D. and Lee, Jeannette Jen-Mai and Lehne, Benjamin and Lehtimaki, Terho and Lieb, Wolfgang and Lim, Su-Chi and Lind, Lars and Lindgren, Cecilia M. and Liu, Jun and Liu, Jianjun and Loeffler, Markus and Loos, Ruth J. F. and Lucae, Susanne and Lukas, Mary Ann and Lyytikainen, Leo-Pekka and Magi, Reedik and Magnusson, Patrik K. E. and Mahajan, Anubha and Martin, Nicholas G. and Martins, Jade and Marz, Winfried and Mascalzoni, Deborah and Matsuda, Koichi and Meisinger, Christa and Meitinger, Thomas and Melander, Olle and Metspalu, Andres and Mikaelsdottir, Evgenia K. and Milaneschi, Yuri and Miliku, Kozeta and Mishra, Pashupati P. and Program, V. A. Million Veteran and Mohlke, Karen L. and Mononen, Nina and Montgomery, Grant W. and Mook-Kanamori, Dennis O. and Mychaleckyj, Josyf C. and Nadkarni, Girish N. and Nalls, Mike A. and Nauck, Matthias and Nikus, Kjell and Ning, Boting and Nolte, Ilja M. and Noordam, Raymond and Olafsson, Isleifur and Oldehinkel, Albertine J. and Orho-Melander, Marju and Ouwehand, Willem H. and Padmanabhan, Sandosh and Palmer, Nicholette D. and Palsson, Runolfur and Penninx, Brenda W. J. H. and Perls, Thomas and Perola, Markus and Pirastu, Mario and Pirastu, Nicola and Pistis, Giorgio and Podgornaia, Anna I. and Polasek, Ozren and Ponte, Belen and Porteous, David J. and Poulain, Tanja and Pramstaller, Peter P. and Preuss, Michael H. and Prins, Bram P. and Province, Michael A. and Rabelink, Ton J. and Raffield, Laura M. and Raitakari, Olli T. and Reilly, Dermot F. and Rettig, Rainer and Rheinberger, Myriam and Rice, Kenneth M. and Ridker, Paul M. and Rivadeneira, Fernando and Rizzi, Federica and Roberts, David J. and Robino, Antonietta and Rossing, Peter and Rudan, Igor and Rueedi, Rico and Ruggiero, Daniela and Ryan, Kathleen A. and Saba, Yasaman and Sabanayagam, Charumathi and Salomaa, Veikko and Salvi, Erika and Saum, Kai-Uwe and Schmidt, Helena and Schmidt, Reinhold and Ben Schottker, and Schulz, Christina-Alexandra and Schupf, Nicole and Shaffer, Christian M. and Shi, Yuan and Smith, Albert V. and Smith, Blair H. and Soranzo, Nicole and Spracklen, Cassandra N. and Strauch, Konstantin and Stringham, Heather M. and Stumvoll, Michael and Svensson, Per O. and Szymczak, Silke and Tai, E-Shyong and Tajuddin, Salman M. and Tan, Nicholas Y. Q. and Taylor, Kent D. and Teren, Andrej and Tham, Yih-Chung and Thiery, Joachim and Thio, Chris H. L. and Thomsen, Hauke and Thorleifsson, Gudmar and Toniolo, Daniela and Tonjes, Anke and Tremblay, Johanne and Tzoulaki, Ioanna and Uitterlinden, Andre G. and Vaccargiu, Simona and Van Dam, Rob M. and Van der Harst, Pim and Van Duijn, Cornelia M. and Edward, Digna R. Velez and Verweij, Niek and Vogelezang, Suzanne and Volker, Uwe and Vollenweider, Peter and Waeber, Gerard and Waldenberger, Melanie and Wallentin, Lars and Wang, Ya Xing and Wang, Chaolong and Waterworth, Dawn M. and Bin Wei, Wen and White, Harvey and Whitfield, John B. and Wild, Sarah H. and Wilson, James F. and Wojczynski, Mary K. and Wong, Charlene and Wong, Tien-Yin and Xu, Liang and Yang, Qiong and Yasuda, Masayuki and Yerges-Armstrong, Laura M. and Zhang, Weihua and Zonderman, Alan B. and Rotter, Jerome I. and Bochud, Murielle and Psaty, Bruce M. and Vitart, Veronique and Wilson, James G. and Dehghan, Abbas and Parsa, Afshin and Chasman, Daniel I. and Ho, Kevin and Morris, Andrew P. and Devuyst, Olivier and Akilesh, Shreeram and Pendergrass, Sarah A. and Sim, Xueling and Boger, Carsten A. and Okada, Yukinori and Edwards, Todd L. and Snieder, Harold and Stefansson, Kari and Hung, Adriana M. and Heid, Iris M. and Scholz, Markus and Teumer, Alexander and Kottgen, Anna and Pattaro, Cristian},
  title     = {A catalog of genetic loci associated with kidney function from analyses of a million individuals},
  series = {Nature genetics},
  volume    = {51},
  journal   = {Nature genetics},
  number    = {6},
  publisher = {Nature Publ. Group},
  address   = {New York},
  organization    = {Lifelines COHort Study},
  issn      = {1061-4036},
  doi       = {10.1038/s41588-019-0407-x},
  pages     = {957 -- +},
  year      = {2019},
  abstract  = {Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic complications. Through transancestry meta-analysis of genome-wide association studies of estimated glomerular filtration rate (eGFR) and independent replication (n = 1,046,070), we identified 264 associated loci (166 new). Of these,147 were likely to be relevant for kidney function on the basis of associations with the alternative kidney function marker blood urea nitrogen (n = 416,178). Pathway and enrichment analyses, including mouse models with renal phenotypes, support the kidney as the main target organ. A genetic risk score for lower eGFR was associated with clinically diagnosed CKD in 452,264 independent individuals. Colocalization analyses of associations with eGFR among 783,978 European-ancestry individuals and gene expression across 46 human tissues, including tubulo-interstitial and glomerular kidney compartments, identified 17 genes differentially expressed in kidney. Fine-mapping highlighted missense driver variants in 11 genes and kidney-specific regulatory variants. These results provide a comprehensive priority list of molecular targets for translational research.},
  language  = {en}
}
@book{BuddrusSchmidt2015,
  author    = {Buddrus, Joachim and Schmidt, Bernd},
  title     = {Grundlagen der organischen Chemie},
  edition   = {5., {\"u}berarb. und aktualisierte Aufl.},
  publisher = {de Gruyter},
  address   = {Berlin},
  isbn      = {978-3-11-030559-3},
  publisher      = {Universit{\"a}t Potsdam},
  pages     = {946},
  year      = {2015},
  language  = {de}
}
@article{GoldmannJanietzSchmidtetal.2004,
  author    = {Goldmann, Daniela and Janietz, Dietmar and Schmidt, C. and Wendorff, Joachim Heinz},
  title     = {Columnar liquid crystalline phases through hydrogen bonding and nanoscale segregation},
  issn      = {0959-9428},
  year      = {2004},
  abstract  = {Two columnar phases forming 2,4,6-triarylamino-1,3,5-triazines have been investigated in binary mixtures with calamitic and non-liquid crystalline benzoic acids carrying one or two alkoxy chains at the aromatic core. The triazines form hydrogen bonded aggregates with the complementary acids. Each investigated equimolar mixture exhibits a columnar mesophase due to segregation of the H-bonded polar core region from the lipophilic aliphatic molecular segments. The cross sectional shape of cylindrical aggregates and, therefore, the two-dimensional lattice symmetries, hexagonal or rectangular, are defined by the number of alkoxy chains of the benzoic acid component},
  language  = {en}
}
@article{GoldmannNordsieckJanietzetal.2004,
  author    = {Goldmann, Daniela and Nordsieck, A. and Janietz, Dietmar and Frese, T. and Schmidt, C. and Wendorff, Joachim Heinz},
  title     = {Smectic and columnar liquid crystalline phases through charge-transfer interactions},
  issn      = {1058-725X},
  year      = {2004},
  abstract  = {New heterocyclic electron donors based on. a 1,3,5-triazine nucleus are presented. Three phenyl rings are grafted to the triazine core either via secondary amino groups or by a direct C,C-linkage and a specific number of decyloxy chains is attached to the molecular periphery. The compounds are non-liquid crystalline in their pure states. Lamellar or columnar mesophases are induced by attractive interactions with electron acceptors},
  language  = {en}
}
@article{SchmidtBechmann2014,
  author    = {Schmidt, Joachim and Bechmann, Wolfgang},
  title     = {Zur Anwendung des Skalarprodukts von Kraft und Weg auf reversible Prozesse (Druck-Volumen-{\"A}nderung, Dehnung, Elektrostatische Wechselwirkung, Hub)},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-69732},
  year      = {2014},
  abstract  = {Wir schlagen einen allgemein anwendbaren Algorithmus vor, der unter Verwendung des Skalarprodukts von Kraft und Weg zum richtigen Vorzeichen in den Gleichungen f{\"u}r die Arbeit und die Potentielle Energie bei reversiblen Prozessen (Druck-Volumen-{\"A}nderung, Dehnung, Elektrostatische Wechselwirkung, Hub)f{\"u}hrt. Wir zeigen, dass es dabei m{\"o}glich ist, systemimmanente oder externe Kr{\"a}fte zu benutzen. Wir zeigen, dass bei Verwendung von systemimmanenten Kr{\"a}ften das Skalarprodukt mit negativem Vorzeichen anzusetzen ist. Zudem ist es sehr wichtig, n{\"o}tige Vorzeichenwechsel bei den einzelnen Schritten zu beachten. Wir betonen dies, weil gelegentlich {\"u}bersehen wird, dass ein Vorzeichenwechsel n{\"o}tig ist, wenn das Wegdifferential ds durch das H{\"o}hendifferential dh beziehungsweise durch das Abstandsdifferential dx oder dr ersetzt werden muss.},
  language  = {de}
}
@misc{LudwigReeseSchmidt2000,
  author    = {Ludwig, Joachim and Reese, Hartmut and Schmidt, Herbert},
  title     = {Sichtweisen auf das lernende Subjekt in der gewerkschaftlichen Bildungsarbeit},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-12658},
  year      = {2000},
  abstract  = {Aus dem Inhalt: Die Bildungskonzeption der Gewerkschaft {\"O}ffentliche Dienste, Transport und Verkehr ({\"O}TV) verweist darauf, 'die Bildungsarbeit st{\"a}ndig weiterzuentwickeln' und sie an ver{\"a}nderte gesellschaftliche und gewerkschaftliche Rahmenbedingungen anzupassen. Deshalb ist das Projekt 'Weiterentwicklung der zentralen Bildungsarbeit'im Fr{\"u}hjahr 1998 initiiert worden, das eine inhaltliche Debatte {\"u}ber Sinn und Zweck zentraler Bildungsarbeit vorantreiben will.},
  language  = {de}
}
@article{MeyerWituckaWallBecheretal.2012,
  author    = {Meyer, Rhonda C. and Witucka-Wall, Hanna and Becher, Martina and Blacha, Anna Maria and Boudichevskaia, Anastassia and D{\"o}rmann, Peter and Fiehn, Oliver and Friedel, Svetlana and von Korff, Maria and Lisec, Jan and Melzer, Michael and Repsilber, Dirk and Schmidt, Renate and Scholz, Matthias and Selbig, Joachim and Willmitzer, Lothar and Altmann, Thomas},
  title     = {Heterosis manifestation during early Arabidopsis seedling development is characterized by intermediate gene expression and enhanced metabolic activity in the hybrids},
  series = {The plant journal},
  volume    = {71},
  journal   = {The plant journal},
  number    = {4},
  publisher = {Wiley-Blackwell},
  address   = {Hoboken},
  issn      = {0960-7412},
  doi       = {10.1111/j.1365-313X.2012.05021.x},
  pages     = {669 -- 683},
  year      = {2012},
  abstract  = {Heterosis-associated cellular and molecular processes were analyzed in seeds and seedlings of Arabidopsis thaliana accessions Col-0 and C24 and their heterotic hybrids. Microscopic examination revealed no advantages in terms of hybrid mature embryo organ sizes or cell numbers. Increased cotyledon sizes were detectable 4 days after sowing. Growth heterosis results from elevated cell sizes and numbers, and is well established at 10 days after sowing. The relative growth rates of hybrid seedlings were most enhanced between 3 and 4 days after sowing. Global metabolite profiling and targeted fatty acid analysis revealed maternal inheritance patterns for a large proportion of metabolites in the very early stages. During developmental progression, the distribution shifts to dominant, intermediate and heterotic patterns, with most changes occurring between 4 and 6 days after sowing. The highest incidence of heterotic patterns coincides with establishment of size differences at 4 days after sowing. In contrast, overall transcript patterns at 4, 6 and 10 days after sowing are characterized by intermediate to dominant patterns, with parental transcript levels showing the largest differences. Overall, the results suggest that, during early developmental stages, intermediate gene expression and higher metabolic activity in the hybrids compared to the parents lead to better resource efficiency, and therefore enhanced performance in the hybrids.},
  language  = {en}
}
@article{GoldmannMahlstedtJanietzetal.1998,
  author    = {Goldmann, Daniela and Mahlstedt, S. and Janietz, Dietmar and Busch, P. and Schmidt, C. and Stracke, A. and Wendorff, Joachim Heinz},
  title     = {Mesomorphic donor-acceptor twin molecules with covalently linked sheet-like pentaalkyne and nitrofluorenone subunits},
  year      = {1998},
  language  = {en}
}
@article{GoldmannJanietzSchmidtetal.1998,
  author    = {Goldmann, Daniela and Janietz, Dietmar and Schmidt, C. and Wendorff, Joachim Heinz},
  title     = {Liquid crystalline 1,3,5-triazines incorporating rod-like azobenzene sub-units},
  year      = {1998},
  language  = {en}
}
@article{PadeSchmidtStumpeetal.1996,
  author    = {Pade, Sylvia and Schmidt, Hartmut and Stumpe, Joachim and Fischer, Thomas M.},
  title     = {(Micro-)fluorescence spectroscopy of side chain polymers with bezanilide moieties},
  year      = {1996},
  language  = {en}
}
@article{GoldmannJanietzSchmidtetal.1996,
  author    = {Goldmann, Daniela and Janietz, Dietmar and Schmidt, C. and Wendorff, Joachim Heinz},
  title     = {Disc-shaped mesogens based on 1,3,5-triazines : variation and induction of columnar mesophases through complementary intermolecular interactions},
  year      = {1996},
  language  = {en}
}
@article{JanietzFestagSchmidtetal.1996,
  author    = {Janietz, Dietmar and Festag, R. and Schmidt, C. and Wendorff, Joachim Heinz},
  title     = {Amphotropic oligomeric 1,3,5-triazines containing disc-shaped pentaalkyne and triphenylene side groups},
  year      = {1996},
  language  = {en}
}
@article{KoetzKoepkeSchmidtNaakeetal.1996,
  author    = {Koetz, Joachim and K{\"o}pke, Heike and Schmidt-Naake, Gudrun and Zarras, Peter and Vogl, Otto},
  title     = {Polyanion-polycation complex formation as a function of the position of the functional groups},
  year      = {1996},
  language  = {en}
}
@article{GoldmannDietelJanietzetal.1998,
  author    = {Goldmann, Daniela and Dietel, Reinhard and Janietz, Dietmar and Schmidt, C. and Wendorff, Joachim Heinz},
  title     = {Sheet-shaped mesogens based on 1,3,5-Triazines : variation of columnar mesophases through intermolecular hydrogen bonding},
  year      = {1998},
  language  = {en}
}
@article{JanietzFestagSchmidtetal.1995,
  author    = {Janietz, Dietmar and Festag, R. and Schmidt, C. and Tsukruk, V. V. and Wendorff, Joachim Heinz},
  title     = {Interfacial behaviour and thermal properties of triazine modified triphenylene oligomers},
  year      = {1995},
  language  = {en}
}
@article{FestagSchmidtWendorffetal.1995,
  author    = {Festag, R. and Schmidt, C. and Wendorff, Joachim Heinz and Janietz, Dietmar},
  title     = {Structure and dynamics of new triazine based polymers with discotic side groups},
  year      = {1995},
  language  = {en}
}
@article{JanietzFestagSchmidtetal.1995,
  author    = {Janietz, Dietmar and Festag, R. and Schmidt, C. and Wendorff, Joachim Heinz},
  title     = {Supramolecular assemblies of new amphotropic oligomers with disc-shaped side groups},
  year      = {1995},
  language  = {en}
}
@article{JanietzFestagSchmidtetal.1994,
  author    = {Janietz, Dietmar and Festag, R. and Schmidt, C. and Wendorff, Joachim Heinz},
  title     = {Self-organization of new oligomers containing disc-shaped side groups},
  year      = {1994},
  language  = {en}
}
@article{BroscheitBuetowEnglertetal.1996,
  author    = {Broscheit, Frank and B{\"u}tow, Martin and Englert, Wolfgang and Jahn, Gert and Klohn, Werner and Knitschky, Wolfgang and Reinecke, Hans-Joachim and M{\"u}ller, Helmut and Reinhardt, Karl Heinz and Schmidt, Marianne and Schmidtke, Kurt-Dietmar and Sch{\"o}pflin, F. and Starke, Rainer and Vahldiek, B. W. and Wehrs, Klaus and Wetzel, J{\"u}rgen},
  title     = {Seydlitz Erdkunde 2},
  publisher = {Schroedel},
  address   = {Hannover},
  pages     = {128 S.},
  year      = {1996},
  language  = {de}
}
@article{SchmidtKundicPenetal.2002,
  author    = {Schmidt, Robert W. and Kundic, T. and Pen, U.-L. and Wambsganß, Joachim and Bergeron, L. E. and Colley, W. and Corson, C. and Hastings, N. G. and Hoyes, T. and Long, D. C. and Loomis, K. A. and Malhotra, S. and Rhoads, J. E. and Stanek, K. Z.},
  title     = {Optical monitoring of the gravitationally lensed quasar Q2237+0305 from APO between June 1995 and January 1998},
  year      = {2002},
  abstract  = {We present a data set of images of the gravitationally lensed quasar Q2237+0305, that was obtained at the Apache Point Observatory (APO) between June 1995 and January 1998. Although the images were taken under variable, often poor seeing conditions and with coarse pixel sampling, photometry is possible for the two brighter quasar images A and B with the help of exact quasar image positions from HST observations. We obtain a light curve with 73 data points for each of the images A and B. There is evidence for a long (ga 100 day) brightness peak in image A in 1996 with an amplitude of about 0.4 to 0.5 mag (relative to 1995), which indicates that microlensing has been taking place in the lensing galaxy. Image B does not vary much over the course of the observation period. The long, smooth variation of the light curve is similar to the results from the OGLE monitoring of the system (Wozniak et al. cite{Wozniak00}). Based on observations obtained with the Apache Point Observatory 3.5-meter telescope, which is owned and operated by the Astrophysical Research Consortium.},
  language  = {en}
}
@book{BechmannSchmidtElschenbroichetal.2001,
  author    = {Bechmann, Wolfgang and Schmidt, Joachim and Elschenbroich, Christoph and Hensel, Friedrich and Hopf, Henning},
  title     = {Einstieg in die Physikalische Chemie f{\"u}r Nebenf{\"a}chler},
  series = {Teubner Studienb{\"u}cher Chemie},
  journal   = {Teubner Studienb{\"u}cher Chemie},
  publisher = {Vieweg+Teubner Verlag},
  address   = {Wiesbaden},
  isbn      = {3-519-00352-X},
  doi       = {10.1007/978-3-322-94876-2},
  pages     = {303 S.},
  year      = {2001},
  abstract  = {Mit einer ausgewogenen Stoffauswahl wird der Leser an das Studium der Physikalischen Chemie herangef{\"u}hrt. Das Verst{\"a}ndnis der Theorie wird durch zahlreiche Aufgabenstellungen und die Angabe ihrer L{\"o}sungswege erleichtert. Das vorliegende Buch gibt dem Studenten dar{\"u}ber hinaus Anregungen f{\"u}r ausgew{\"a}hlte Experimente zu den behandelten Teilgebieten. In der Durchf{\"u}hrung und Auswertung der Experimente kann der Student erneut {\"u}berpr{\"u}fen, wie gut es ihm gelungen ist, ein Grundverst{\"a}ndnis f{\"u}r physikalisch-chemische Zusammenh{\"a}nge zu entwickeln.},
  language  = {de}
}
@article{SchmidtWambsganssPenetal.2001,
  author    = {Schmidt, Robert W. and Wambsganß, Joachim and Pen, U.-L. and Turner, E. L.},
  title     = {APO monitoring of Q2237+0305 in 1995-97 : evidence for microlensing},
  isbn      = {1-583-81074-9},
  year      = {2001},
  language  = {en}
}
@book{BechmannSchmidt2000,
  author    = {Bechmann, Wolfgang and Schmidt, Joachim},
  title     = {Struktur- und Stoffanalytik mit spektroskopischen Methoden},
  series = {Teubner Studienb{\"u}cher Chemie},
  journal   = {Teubner Studienb{\"u}cher Chemie},
  publisher = {Vieweg+Teubner Verlag},
  address   = {Wiesbaden},
  isbn      = {3-519-03552-9},
  doi       = {10.1007/978-3-322-80123-4},
  pages     = {179 S.},
  year      = {2000},
  language  = {de}
}
@article{WambsganssSchmidtColleyetal.2000,
  author    = {Wambsganß, Joachim and Schmidt, Robert W. and Colley, W. and Kundic, T. and Turner, E. L.},
  title     = {Microlensing results from APO monitoring of the double quasar Q0957+561A,B between 1995 and 1998},
  year      = {2000},
  abstract  = {If the halo of the lensing galaxy 0957+561 is made of massive compact objects (MACHOs), they must affect the lightcurves of the quasar images Q0957+561 A and B differently. We search for this microlensing effect in the double quasar by comparing monitoring data for the two images A and B - obtained with the 3.5m Apache Point Observatory from 1995 to 1998 - with intensive numerical simulations. This way we test whether the halo of the lensing galaxy can be made of MACHOs of various masses. We can exclude a halo entirely made out of MACHOs with masses between 10-6 Msun and 10-2 Msun for quasar sizes of less than 3x 1014 h60-1/2 cm, hereby extending previous limits upwards by one order of magnitude.},
  language  = {en}
}
@article{WambsganssHasingerGiacconietal.2000,
  author    = {Wambsganß, Joachim and Hasinger, G{\"u}nther and Giacconi, R. and Gunn, J. E. and Lehmann, Ingo and Schmidt, M. and Schneider, D. P. and Stanke, Thomas and Tr{\"u}mper, J. and Woods, D. and Zamorani, G.},
  title     = {A Distant X-ray Selected, Gravitationally-Lensing Galaxy Cluster},
  year      = {2000},
  language  = {en}
}
@article{LehmannHasingerGiacconietal.2000,
  author    = {Lehmann, Ingo and Hasinger, G{\"u}nther and Giacconi, R. and Gunn, J. E. and Schmidt, M. and Schneider, D. P. and Stanke, Thomas and Tr{\"u}mper, J. and Wambsganß, Joachim and Woods, D. and Zamorani, G.},
  title     = {One of the highest redshift X-Ray selected clusters of galaxies},
  isbn      = {3-540-67163-3},
  year      = {2000},
  language  = {en}
}
@article{SchwarzAndraeArnoldetal.1999,
  author    = {Schwarz, W. H. Eugen and Andrae, Dirk and Arnold, S. R. and Heidberg, Joachim and Hellmann jr., H. and Hinze, J. and Karachalios, A. and Kovner, M. A. and Schmidt, P. C. and Z{\"u}licke, Lutz},
  title     = {Hans G. Hellmann (1903 - 1938) : ein deutscher Pionier der Quantenchemie in Moskau},
  year      = {1999},
  language  = {de}
}
@article{SchwarzAndraeArnoldetal.1999,
  author    = {Schwarz, W. H. Eugen and Andrae, Dirk and Arnold, S. R. and Heidberg, Joachim and Hellmann jr., H. and Hinze, J. and Karachalios, A. and Kovner, M. A. and Schmidt, P. C. and Z{\"u}licke, Lutz},
  title     = {Hans G. Hellmann (1903 - 1938) : ein Pionier der Quantenchemie},
  year      = {1999},
  language  = {de}
}
@article{WillnerGerdesMassonneetal.2011,
  author    = {Willner, Arne P. and Gerdes, Axel and Massonne, Hans-Joachim and Schmidt, Alexander and Sudo, Masafumi and Thomson, Stuart N. and Vujovich, Graciela},
  title     = {The geodynamics of collision of a microplate (Chilenia) in Devonian times deduced by the pressure-temperature-time evolution within part of a collisional belt (Guarguaraz Complex, W-Argentina)},
  series = {Contributions to mineralogy and petrology},
  volume    = {162},
  journal   = {Contributions to mineralogy and petrology},
  number    = {2},
  publisher = {Springer},
  address   = {New York},
  issn      = {0010-7999},
  doi       = {10.1007/s00410-010-0598-8},
  pages     = {303 -- 327},
  year      = {2011},
  abstract  = {The Guarguaraz Complex in West Argentina formed during collision between the microplate Chilenia and South America. It is composed of neritic clastic metasediments with intercalations of metabasic and ultrabasic rocks of oceanic origin. Prograde garnet growth in metapelite and metabasite occurred between 1.2 GPa, 470 degrees C and 1.4 GPa, 530 degrees C, when the penetrative s(2)-foliation was formed. The average age of garnet crystallization of 390 +/- 2 Ma (2 sigma) was determined from three four-point Lu-Hf mineral isochrones from metapelite and metabasite samples and represents the time of collision. Peak pressure conditions are followed by a decompression path with slight heating at 0.5 GPa, 560 degrees C. Fluid release during decompression caused equilibration of mineral compositions at the rims and also aided Ar diffusion. An Ar-40/39 Ar plateau age of white mica at 353 +/- 1 Ma (1 sigma) indicates the time of cooling below 350-400 degrees C. These temperatures were attained at pressures of 0.2-0.3 GPa, indicative of an average exhumation rate of >= 1 mm/a for the period 390-353 Ma. Late hydrous influx at 0.1-0.3 GPa caused pervasive growth of sericite and chlorite and reset the Ar/Ar ages of earlier coarse-grained white mica. At 284-295 Ma, the entire basement cooled below 280 degrees C (fission track ages of zircon) after abundant post-collisional granitoid intrusion. The deeply buried epicontinental sedimentary rocks, the high peak pressure referring to a low metamorphic geotherm of 10-12 degrees C/km, and the decompression/heating path are characteristics of material buried and exhumed within a (micro) continent-continent collisional setting.},
  language  = {en}
}
@article{Schmidt2015,
  author    = {Schmidt, Joachim},
  title     = {Die Arbeit bei irreversibler Druck-Volumen-{\"A}nderung},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-74931},
  year      = {2015},
  abstract  = {For the calculation of the work in an irreversible pressure-volume change, we propose approxima-tions, which in contrast to the usual representation in the literature reflect the work performed during expansion and compression symmetrically. The calculations are based on the Reversible-Share-Theorem: Is used the force to overcome for calculating the work, so it captures only the configurational reversible work share.},
  language  = {de}
}
@misc{SaritoprakVorpahlTuranetal.2016,
  author    = {Saritoprak, Zeki and Vorpahl, Daniel and Turan, Hakan and Arslan, Hakki and Zoref, Arye and Tarabieh, Abdallah and Yeshaya, Joachim and Anzi, Menashe and Merkur, Lianne and Schmidt, Daniela and Schuster, Dirk and Langer, Armin and Blum, Rahel and St{\"u}rmann, Jakob and Pohlmann, Julia and Schulz, Michael Karl and Arnold, Rafael D. and Salzer, Dorothea M. and Geißler-Gr{\"u}nberg, Anke and Talabardon, Susanne and Rasumny, Wiebke and Stellmacher, Martha and Denz, Rebekka and Walter, Simon and Gr{\"o}zinger, Elvira},
  title     = {PaRDeS : Zeitschrift der Vereinigung f{\"u}r J{\"u}dische Studien = Muslimisch-J{\"u}discher Dialog},
  series = {PaRDeS : Zeitschrift der Vereinigung f{\"u}r J{\"u}dische Studien e.V.},
  journal   = {PaRDeS : Zeitschrift der Vereinigung f{\"u}r J{\"u}dische Studien e.V.},
  number    = {22},
  editor    = {Riemer, Nathanael and Sanci, Kadir and Schulz, Michael Karl},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-86956-370-1},
  issn      = {1614-6492},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-95416},
  pages     = {280},
  year      = {2016},
  abstract  = {PaRDeS. Zeitschrift der Vereinigung f{\"u}r J{\"u}dische Studien e.V., m{\"o}chte die fruchtbare und facettenreiche Kultur des Judentums sowie seine Ber{\"u}hrungspunkte zur Umwelt in den unterschiedlichen Bereichen dokumentieren. Daneben dient die Zeitschrift als Forum zur Positionierung der F{\"a}cher J{\"u}dische Studien und Judaistik innerhalb des wissenschaftlichen Diskurses sowie zur Diskussion ihrer historischen und gesellschaftlichen Verantwortung.},
  language  = {de}
}
@article{HenschDahmRitteretal.2019,
  author    = {Hensch, Martin and Dahm, Torsten and Ritter, Joachim and Heimann, Sebastian and Schmidt, Bernd and Stange, Stefan and Lehmann, Klaus},
  title     = {Deep low-frequency earthquakes reveal ongoing magmatic recharge beneath Laacher See Volcano (Eifel, Germany)},
  series = {Geophysical journal international},
  volume    = {216},
  journal   = {Geophysical journal international},
  number    = {3},
  publisher = {Oxford Univ. Press},
  address   = {Oxford},
  issn      = {0956-540X},
  doi       = {10.1093/gji/ggy532},
  pages     = {2025 -- 2036},
  year      = {2019},
  abstract  = {The occurrence of deep low-frequency (DLF) microearthquakes beneath volcanoes is commonly attributed to mass transport in the volcanic plumbing system and used to infer feeding channels from and into magma reservoirs. The key question is how magmas migrate from depth to the shallow crust and whether magma reservoirs are currently being recharged. For the first time since the improvement of the local seismic networks in the East Eifel region (Rhineland-Palatinate, Germany), we detect and locate recurrent DLF earthquakes in the lower crust and upper mantle beneath the Laacher See Volcano (LSV), using a joint data set of permanent sensors and a temporary deployment. So far, eight DLF earthquake sequences were observed in four distinct clusters between 10 and 40 km depth. These clusters of weak events (M-L< 2) align along an approximately 80. southeast dipping line south of the LSV. Moment tensor solutions of these events have large shear components, and the irregular dispersion and long coda of body waves indicate interaction processes between shear cracks and fluids. We find a rotation of P-axes orientation for shallow tectonic earthquakes compared to DLF events, indicating that the stress field in the depth interval of DLF events might favour a vertical migration of magma or magmatic fluids. The caldera of the LSV was formed by the last major eruption of the East Eifel Volcanic Field only 12.9 kyr ago, fed by a shallow magma chamber at 5-8 km depth and erupting a total magma volume of 6.7 km(3). The observed DLF earthquake activity and continuous volcanic gas emissions around the LSV indicate an active magmatic system, possibly connected with an upper mantle melt zone.},
  language  = {en}
}
@article{SchmidtMieuletHubbertenetal.2013,
  author    = {Schmidt, Romy and Mieulet, Delphine and Hubberten, Hans-Michael and Obata, Toshihiro and H{\"o}fgen, Rainer and Fernie, Alisdair R. and Fisahn, Joachim and Segundo, Blanca San and Guiderdoni, Emmanuel and Schippers, Jos H. M. and M{\"u}ller-R{\"o}ber, Bernd},
  title     = {Salt-responsive ERF1 regulates reactive oxygen species-dependent signaling during the initial response to salt stress in rice},
  series = {The plant cell},
  volume    = {25},
  journal   = {The plant cell},
  number    = {6},
  publisher = {American Society of Plant Physiologists},
  address   = {Rockville},
  issn      = {1040-4651},
  doi       = {10.1105/tpc.113.113068},
  pages     = {2115 -- 2131},
  year      = {2013},
  abstract  = {Early detection of salt stress is vital for plant survival and growth. Still, the molecular processes controlling early salt stress perception and signaling are not fully understood. Here, we identified SALT-RESPONSIVE ERF1 (SERF1), a rice (Oryza sativa) transcription factor (TF) gene that shows a root-specific induction upon salt and hydrogen peroxide (H2O2) treatment. Loss of SERF1 impairs the salt-inducible expression of genes encoding members of a mitogen-activated protein kinase (MAPK) cascade and salt tolerance-mediating TFs. Furthermore, we show that SERF1-dependent genes are H2O2 responsive and demonstrate that SERF1 binds to the promoters of MAPK KINASE KINASE6 (MAP3K6), MAPK5, DEHYDRATION-RESPONSIVE ELEMENT BINDING2A (DREB2A), and ZINC FINGER PROTEIN179 (ZFP179) in vitro and in vivo. SERF1 also directly induces its own gene expression. In addition, SERF1 is a phosphorylation target of MAPK5, resulting in enhanced transcriptional activity of SERF1 toward its direct target genes. In agreement, plants deficient for SERF1 are more sensitive to salt stress compared with the wild type, while constitutive overexpression of SERF1 improves salinity tolerance. We propose that SERF1 amplifies the reactive oxygen species-activated MAPK cascade signal during the initial phase of salt stress and translates the salt-induced signal into an appropriate expressional response resulting in salt tolerance.},
  language  = {en}
}