@article{SauerKleineVehn2019,
  author    = {Sauer, Michael and Kleine-Vehn, J{\"u}rgen},
  title     = {PIN-FORMED and PIN-LIKES auxin transport facilitators},
  series = {Development : Company of Biologists},
  volume    = {146},
  journal   = {Development : Company of Biologists},
  number    = {15},
  publisher = {Company biologists ltd},
  address   = {Cambridge},
  issn      = {0950-1991},
  doi       = {10.1242/dev.168088},
  pages     = {5},
  year      = {2019},
  abstract  = {The phytohormone auxin influences virtually all aspects of plant growth and development. Auxin transport across membranes is facilitated by, among other proteins, members of the PIN-FORMED (PIN) and the structurally similar PIN-LIKES (PILS) families, which together govern directional cell-to-cell transport and intracellular accumulation of auxin. Canonical PIN proteins, which exhibit a polar localization in the plasma membrane, determine many patterning and directional growth responses. Conversely, the less-studied noncanonical PINs and PILS proteins, which mostly localize to the endoplasmic reticulum, attenuate cellular auxin responses. Here, and in the accompanying poster, we provide a brief summary of current knowledge of the structure, evolution, function and regulation of these auxin transport facilitators.},
  language  = {en}
}
@article{SauerWartenbergSachinidisetal.2004,
  author    = {Sauer, Heinrich and Wartenberg, Maria and Sachinidis, A. and Hescheler, J{\"u}rgen},
  title     = {The development of the cardiovascular system in embryoid bodies deriverd from embryonic stem cells},
  isbn      = {1-588- 29113-8},
  year      = {2004},
  language  = {en}
}
@article{SachinidisWartenbergSaueretal.2004,
  author    = {Sachinidis, A. and Wartenberg, Maria and Sauer, Heinrich and Hescheler, J{\"u}rgen},
  title     = {Transcription factors, growth factors and signal cascades capable of priming morphogenesis of heart},
  isbn      = {1-588- 29113-8},
  year      = {2004},
  language  = {en}
}
@article{RahimiIsachenkoSaueretal.2004,
  author    = {Rahimi, G. and Isachenko, E. and Sauer, Heinrich and Isachenko, V. and Wartenberg, Maria and Tawadros, S. and Hescheler, J{\"u}rgen and Mallmann, P. and Nawroth, F.},
  title     = {Comparison of necrosis in human ovarian tissue after conventional slow freezing or vitrification and transplantation in ovarectomized SCID mice},
  year      = {2004},
  language  = {en}
}
@article{SauerNeukirchenRahimietal.2004,
  author    = {Sauer, Heinrich and Neukirchen, W. and Rahimi, G. and Gr{\"u}nbeck, Frank and Hescheler, J{\"u}rgen and Wartenberg, Maria},
  title     = {Involvement of reactive oxygen species in cardiotropin-1 (CT-1)-induced cell proliferation of cardiomyocytes differentiated from murine embryonic stem cells},
  year      = {2004},
  language  = {en}
}
@article{NaWartenbergNauetal.2003,
  author    = {Na, L. and Wartenberg, Maria and Nau, H. and Hescheler, J{\"u}rgen and Sauer, Heinrich},
  title     = {Anticonvulsant valproic acid inhibits cardiomyocyte differentiation of embryonic stem cells by increasing intracellular levels of reactive oxygen species},
  year      = {2003},
  language  = {en}
}
@article{WartenbergWolfBuddeetal.2003,
  author    = {Wartenberg, Maria and Wolf, Sandra and Budde, Paula and Gr{\"u}nbeck, Frank and Acker, Helmut and Hescheler, J{\"u}rgen and Wartenberg, Gerda and Sauer, Heinrich},
  title     = {The antimalaria agent artemisinin exerts antiangiogenic effects in mouse embryonic stem cell-derived embryoid bodies},
  year      = {2003},
  language  = {en}
}
@article{SauerWeferVetrugnoetal.2003,
  author    = {Sauer, Heinrich and Wefer, K. and Vetrugno, V. and Pocchiari, M. and Gissel, C. and Sachinidis, A. and Hescheler, J{\"u}rgen and Wartenberg, Maria},
  title     = {Regulation of intrinsic prion protein by growth factors and TNF-alpha : the role of intracellular reactive oxygen species},
  year      = {2003},
  language  = {en}
}
@article{WartenbergLingMueschenetal.2003,
  author    = {Wartenberg, Maria and Ling, Frederike C. and M{\"u}schen, Markus and Klein, Florian and Acker, Helmut and Gassmann, Max and Petrat, Kerstin and P{\"u}tz, Volker and Hescheler, J{\"u}rgen and Sauer, Heinrich},
  title     = {Regulation of the multidrug resistance transporter P-glycorotein by hypoxia-inducible factor (HIF-1) and reactive oxygen species},
  year      = {2003},
  language  = {en}
}
@article{SachinidisGisselNierhoffetal.2003,
  author    = {Sachinidis, A. and Gissel, C. and Nierhoff, D. and Hippler-Altenburg, Rita and Sauer, Heinrich and Wartenberg, Maria and Hescheler, J{\"u}rgen},
  title     = {Identification of plateled-derived growth factor-BB as cardiogenisis-inducing factor in mouse embryonic stem cells under serum-free conditions},
  year      = {2003},
  language  = {en}
}
@article{RahimiIsachenkoSaueretal.2003,
  author    = {Rahimi, G. and Isachenko, E. and Sauer, Heinrich and Isachenko, V. and Wartenberg, Maria and Hescheler, J{\"u}rgen and Mallmann, P. and Nawroth, F.},
  title     = {Effect of different vitrification protocols for human ovarian tissue on reactive oxygen species and apoptosis},
  year      = {2003},
  language  = {en}
}
@article{WartenbergBuddedeMareesetal.2003,
  author    = {Wartenberg, Maria and Budde, Paula and de Mare{\´e}s, M. and Tsang, S. Y. and Huang, Y. and Chen, Zhen-Yu and Hescheler, J{\"u}rgen and Sauer, Heinrich},
  title     = {Inhibition of tumor-induced angiogenesis and matrix-metalloproteinase expression in confrontation cultures of ES cell-derived embryoid bodies and multicellular tumor spheroids by plant ingredients use},
  year      = {2003},
  language  = {en}
}
@misc{KleineVehnSauer2017,
  author    = {Kleine-Vehn, J{\"u}rgen and Sauer, Michael},
  title     = {Preface},
  series = {Plant Hormones: Methods and Protocols},
  volume    = {1497},
  journal   = {Plant Hormones: Methods and Protocols},
  editor    = {Kleine-Vehn, J{\"u}rgen and Sauer, Michael},
  edition   = {3},
  publisher = {Springer},
  address   = {New York},
  isbn      = {978-1-4939-6469-7},
  issn      = {1064-3745},
  doi       = {10.1007/978-1-4939-6469-7},
  pages     = {V -- V},
  year      = {2017},
  language  = {en}
}
@article{SauerSteinGlatzeletal.2015,
  author    = {Sauer, Daniela and Stein, Christine and Glatzel, Stephan and K{\"u}hn, J{\"u}rgen and Zarei, Mehdi and Stahr, Karl},
  title     = {Duricrusts in soils of the Alentejo (southern Portugal)-types, distribution, genesis and time of their formation},
  series = {Journal of soils and sediments : protection, risk assessment and remediation},
  volume    = {15},
  journal   = {Journal of soils and sediments : protection, risk assessment and remediation},
  number    = {6},
  publisher = {Springer},
  address   = {Heidelberg},
  issn      = {1439-0108},
  doi       = {10.1007/s11368-015-1066-x},
  pages     = {1437 -- 1453},
  year      = {2015},
  abstract  = {This paper reports on extremely thick and massive duricrusts in soils of two basins in the Alentejo (southern Portugal). Since different types of duricrusts (calcretes, silcretes and palycretes) have been reported from other regions in the Mediterranean, the purpose of this study was to identify the cementing agents in the duricrusts and to compare their composition in the two basins. Moreover, the study aimed at identifying the processes involved in duricrust formation, and especially the role of topography and lateral water and element transport in the landscape, and drawing conclusions about environmental conditions and time of duricrust formation. After studying an extensive number of road cuts in the field and mapping soil patterns in parts of the two basins by manual augering, ten pedons were selected for detailed description and sampling. Thin sections were analysed under a petrographic microscope, focusing on the micromorphology and optical properties of the cementing materials. Selected samples were studied by scanning electron microscopy and energy-dispersive X-ray spectroscopy to reconfirm the optical identification. The laboratory analyses included pH, carbonate contents, and X-ray diffraction analysis. The duricrusts in the eastern Sado basin are indurated by silica. Combination of XRD and thin section analysis allowed to identify opal-CT as a major component, while opal-A is present to a lesser extent, and chalcedony is very rare. The cementing materials of the duricrusts in the Oriola basin are palygorskite and calcite, which may occur alone or in combination within a soil profile. The thick duricrusts formed in the basins through precipitation of calcite, palygorskite and silica from lateral water flows, which ran from the Serra de Portel into the basins, during short moist seasons in a generally warm, semi-arid climate with strong evapotranspiration. Lithology of the upper catchment areas (element sources) and topography control the spatial distribution of the different duricrusts. Their formation took place mainly during the Pliocene. Palygorskite transformation to smectite in the upper parts of the palycretes indicates that palygorskite is unstable in the present (more humid, typical Mediterranean) climate. This study demonstrates the potential role of lateral water and element transport in landscapes that need to be considered in pedological studies and concepts, and the use of mineral indicators of past climates such as palygorskite and the ageing stage of silica precipitations as tools for reconstructing environmental conditions and possible time of duricrust formation.},
  language  = {en}
}
@article{FinkSchumacherSchlegeletal.2021,
  author    = {Fink, Julian and Schumacher, Fabian and Schlegel, Jan and Stenzel, Philipp and Wigger, Dominik and Sauer, Markus and Kleuser, Burkhard and Seibel, J{\"u}rgen},
  title     = {Azidosphinganine enables metabolic labeling and detection of sphingolipid de novo synthesis},
  series = {Organic \& biomolecular chemistry : an international journal of synthetic, physical and biomolecular organic chemistry},
  volume    = {19},
  journal   = {Organic \& biomolecular chemistry : an international journal of synthetic, physical and biomolecular organic chemistry},
  number    = {10},
  publisher = {Royal Society of Chemistry},
  address   = {Cambridge},
  issn      = {1477-0520},
  doi       = {10.1039/d0ob02592e},
  pages     = {2203 -- 2212},
  year      = {2021},
  abstract  = {Here were report the combination of biocompatible click chemistry of omega-azidosphinganine with fluorescence microscopy and mass spectrometry as a powerful tool to elaborate the sphingolipid metabolism. The azide probe was efficiently synthesized over 13 steps starting from l-serine in an overall yield of 20\% and was used for live-cell fluorescence imaging of the endoplasmic reticulum in living cells by bioorthogonal click reaction with a DBCO-labeled fluorophore revealing that the incorporated analogue is mainly localized in the endoplasmic membrane like the endogenous species. A LC-MS(/MS)-based microsomal in vitro assay confirmed that omega-azidosphinganine mimics the natural species enabling the identification and analysis of metabolic breakdown products of sphinganine as a key starting intermediate in the complex sphingolipid biosynthetic pathways. Furthermore, the sphinganine-fluorophore conjugate after click reaction was enzymatically tolerated to form its dihydroceramide and ceramide metabolites. Thus, omega-azidosphinganine represents a useful biofunctional tool for metabolic investigations both by in vivo fluorescence imaging of the sphingolipid subcellular localization in the ER and by in vitro high-resolution mass spectrometry analysis. This should reveal novel insights of the molecular mechanisms sphingolipids and their processing enzymes have e.g. in infection.},
  language  = {en}
}
@inproceedings{KurbelNowakAzodietal.2015,
  author    = {Kurbel, Karl and Nowak, Dawid and Azodi, Amir and Jaeger, David and Meinel, Christoph and Cheng, Feng and Sapegin, Andrey and Gawron, Marian and Morelli, Frank and Stahl, Lukas and Kerl, Stefan and Janz, Mariska and Hadaya, Abdulmasih and Ivanov, Ivaylo and Wiese, Lena and Neves, Mariana and Schapranow, Matthieu-Patrick and F{\"a}hnrich, Cindy and Feinbube, Frank and Eberhardt, Felix and Hagen, Wieland and Plauth, Max and Herscheid, Lena and Polze, Andreas and Barkowsky, Matthias and Dinger, Henriette and Faber, Lukas and Montenegro, Felix and Czach{\´o}rski, Tadeusz and Nycz, Monika and Nycz, Tomasz and Baader, Galina and Besner, Veronika and Hecht, Sonja and Schermann, Michael and Krcmar, Helmut and Wiradarma, Timur Pratama and Hentschel, Christian and Sack, Harald and Abramowicz, Witold and Sokolowska, Wioletta and Hossa, Tymoteusz and Opalka, Jakub and Fabisz, Karol and Kubaczyk, Mateusz and Cmil, Milena and Meng, Tianhui and Dadashnia, Sharam and Niesen, Tim and Fettke, Peter and Loos, Peter and Perscheid, Cindy and Schwarz, Christian and Schmidt, Christopher and Scholz, Matthias and Bock, Nikolai and Piller, Gunther and B{\"o}hm, Klaus and Norkus, Oliver and Clark, Brian and Friedrich, Bj{\"o}rn and Izadpanah, Babak and Merkel, Florian and Schweer, Ilias and Zimak, Alexander and Sauer, J{\"u}rgen and Fabian, Benjamin and Tilch, Georg and M{\"u}ller, David and Pl{\"o}ger, Sabrina and Friedrich, Christoph M. and Engels, Christoph and Amirkhanyan, Aragats and van der Walt, Est{\´e}e and Eloff, J. H. P. and Scheuermann, Bernd and Weinknecht, Elisa},
  title     = {HPI Future SOC Lab},
  editor    = {Meinel, Christoph and Polze, Andreas and Oswald, Gerhard and Strotmann, Rolf and Seibold, Ulrich and Schulzki, Bernhard},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-102516},
  pages     = {iii, 154},
  year      = {2015},
  abstract  = {Das Future SOC Lab am HPI ist eine Kooperation des Hasso-Plattner-Instituts mit verschiedenen Industriepartnern. Seine Aufgabe ist die Erm{\"o}glichung und F{\"o}rderung des Austausches zwischen Forschungsgemeinschaft und Industrie. Am Lab wird interessierten Wissenschaftlern eine Infrastruktur von neuester Hard- und Software kostenfrei f{\"u}r Forschungszwecke zur Verf{\"u}gung gestellt. Dazu z{\"a}hlen teilweise noch nicht am Markt verf{\"u}gbare Technologien, die im normalen Hochschulbereich in der Regel nicht zu finanzieren w{\"a}ren, bspw. Server mit bis zu 64 Cores und 2 TB Hauptspeicher. Diese Angebote richten sich insbesondere an Wissenschaftler in den Gebieten Informatik und Wirtschaftsinformatik. Einige der Schwerpunkte sind Cloud Computing, Parallelisierung und In-Memory Technologien. In diesem Technischen Bericht werden die Ergebnisse der Forschungsprojekte des Jahres 2015 vorgestellt. Ausgew{\"a}hlte Projekte stellten ihre Ergebnisse am 15. April 2015 und 4. November 2015 im Rahmen der Future SOC Lab Tag Veranstaltungen vor.},
  language  = {en}
}