@article{ReilBinderFreiseetal.2018, author = {Reil, Daniela and Binder, Florian and Freise, Jona and Imholt, Christian and Beyrers, Konrad and Jacob, Jens and Kr{\"u}ger, Detlev H. and Hofmann, J{\"o}rg and Dreesman, Johannes and Ulrich, Rainer G{\"u}nter}, title = {Hantaviren in Deutschland}, series = {Berliner und M{\"u}nchener tier{\"a}rztliche Wochenschrift}, volume = {131}, journal = {Berliner und M{\"u}nchener tier{\"a}rztliche Wochenschrift}, number = {11-12}, publisher = {Schl{\"u}tersche Verlagsgesellschaft mbH \& Co. KG.}, address = {Hannover}, issn = {0005-9366}, doi = {10.2376/0005-9366-18003}, pages = {453 -- 464}, year = {2018}, abstract = {Hantaviruses are small mammal-associated pathogens that are found in rodents but also in shrews, moles and bats. Aim of this manuscript is to give a current overview of the epidemiology and ecology of hantaviruses in Germany and to discuss respective models for the prediction of virus outbreaks. In Germany the majority of human disease cases are caused by the Puumala virus (PUUV), transmitted by the bank vole (Myodes glareolus). PUUV is associated with the Western evolutionary lineage of the bank vole and is not present in the eastern and northern parts of Germany. A second human pathogenic hantavirus is the Dobrava-Belgrade virus (DOBV), genotype Kurkino; its reservoir host, the striped field mouse (Apodemus agrarius), is mostly occurring in the eastern part of Germany. A PUUV-related hantavirus is the rarely pathogenic Tula virus (TULV), that is associated with the common vole (Microtus arvalis). In addition, Seewis virus, Asikkala virus, and Bruges virus are shrew- and mole-associated hantaviruses with still unknown pathogenicity in humans. Human disease cases are associated with the different hantaviruses according to their regional distribution. The viruses can cause mild to severe but also subclinical courses of the respective disease. The number of human PUUV disease cases in 2007, 2010, 2012, 2015 and 2017 correlates with the occurrence of high levels of seed production of beech trees ("beech mast") in the preceding year. Models based on weather parameters for the prediction of PUUV disease clusters as developed in recent years need further validation and optimisation. in addition to the abundance of infected reservoir rodents, the exposure behaviour of humans affects the risk of human infection. The application of robust forecast models can assist the public health service to develop and communicate spatially and temporally targeted information. Thus, further recommendations to mitigate infection risk for the public may be provided.}, language = {de} } @article{HoermanndosSantosMorkischetal.2017, author = {H{\"o}rmann, Simon and dos Santos, Luara Ferreira and Morkisch, Nadine and Jettkowski, Katrin and Sillis, Moran and Devan, Hemakumar and Kanagasabai, Parimala S. and Schmidt, Henning and Kr{\"u}ger, J{\"o}rg and Dohle, Christian and Regenbrecht, Holger and Hale, Leigh and Cutfield, Nicholas J.}, title = {Computerised mirror therapy with Augmented Reflection Technology for early stroke rehabilitation}, series = {Disability and rehabilitation : an international, multidisciplinary journal}, volume = {39}, journal = {Disability and rehabilitation : an international, multidisciplinary journal}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {0963-8288}, doi = {10.1080/09638288.2017.1291765}, pages = {1503 -- 1514}, year = {2017}, abstract = {Purpose: New rehabilitation strategies for post-stroke upper limb rehabilitation employing visual stimulation show promising results, however, cost-efficient and clinically feasible ways to provide these interventions are still lacking. An integral step is to translate recent technological advances, such as in virtual and augmented reality, into therapeutic practice to improve outcomes for patients. This requires research on the adaptation of the technology for clinical use as well as on the appropriate guidelines and protocols for sustainable integration into therapeutic routines. Here, we present and evaluate a novel and affordable augmented reality system (Augmented Reflection Technology, ART) in combination with a validated mirror therapy protocol for upper limb rehabilitation after stroke. Results: The results showed that the combination and application of the Berlin Protocol for Mirror Therapy together with ART was feasible for clinical use. This combination was integrated into the therapeutic plan of subacute stroke patients at the two clinical locations where the second part of this research was conducted. Conclusions: Our findings pave the way for using technology to provide mirror therapy in clinical settings and show potential for the more effective use of inpatient time and enhanced recoveries for patients. IMPLICATIONS FOR REHABILITATION Computerised Mirror Therapy is feasible for clinical use Augmented Reflection Technology can be integrated as an adjunctive therapeutic intervention for subacute stroke patients in an inpatient setting Virtual Rehabilitation devices such as Augmented Reflection Technology have considerable potential to enhance stroke rehabilitation}, language = {en} } @article{CironeNegrettiCalarcoetal.2005, author = {Cirone, M. A. and Negretti, Antonio and Calarco, T. and Kr{\"u}ger, P. and Schmiedmayer, J{\"o}rg}, title = {A simple quantum gate with atom chips}, year = {2005}, abstract = {We present a simple scheme for implementing an atomic phase gate using two degrees of freedom for each atom and discuss its realization with cold rubidium atoms on atom chips. We investigate the performance of this collisional phase gate and show that gate operations with high fidelity can be realized in magnetic traps that are currently available on atom chips}, language = {en} } @article{MuellerFoerstendorfSteudtneretal.2019, author = {M{\"u}ller, Katharina and Foerstendorf, Harald and Steudtner, Robin and Tsushima, Satoru and Kumke, Michael Uwe and Lef{\`e}vre, Gr{\´e}gory and Rothe, J{\"o}rg and Mason, Harris and Szab{\´o}, Zolt{\´a}n and Yang, Ping and Adam, Christian K. R. and Andr{\´e}, R{\´e}mi and Brennenstuhl, Katlen and Chiorescu, Ion and Cho, Herman M. and Creff, Ga{\"e}lle and Coppin, Fr{\´e}d{\´e}ric and Dardenne, Kathy and Den Auwer, Christophe and Drobot, Bj{\"o}rn and Eidner, Sascha and Hess, Nancy J. and Kaden, Peter and Kremleva, Alena and Kretzschmar, Jerome and Kr{\"u}ger, Sven and Platts, James A. and Panak, Petra and Polly, Robert and Powell, Brian A. and Rabung, Thomas and Redon, Roland and Reiller, Pascal E. and R{\"o}sch, Notker and Rossberg, Andr{\´e} and Scheinost, Andreas C. and Schimmelpfennig, Bernd and Schreckenbach, Georg and Skerencak-Frech, Andrej and Sladkov, Vladimir and Solari, Pier Lorenzo and Wang, Zheming and Washton, Nancy M. and Zhang, Xiaobin}, title = {Interdisciplinary Round-Robin Test on molecular spectroscopy of the U(VI) Acetate System}, series = {ACS omega / American Chemical Society}, volume = {4}, journal = {ACS omega / American Chemical Society}, number = {5}, publisher = {American Chemical Society}, address = {Washington}, issn = {2470-1343}, doi = {10.1021/acsomega.9b00164}, pages = {8167 -- 8177}, year = {2019}, abstract = {A comprehensive molecular analysis of a simple aqueous complexing system. U(VI) acetate. selected to be independently investigated by various spectroscopic (vibrational, luminescence, X-ray absorption, and nuclear magnetic resonance spectroscopy) and quantum chemical methods was achieved by an international round-robin test (RRT). Twenty laboratories from six different countries with a focus on actinide or geochemical research participated and contributed to this scientific endeavor. The outcomes of this RRT were considered on two levels of complexity: first, within each technical discipline, conformities as well as discrepancies of the results and their sources were evaluated. The raw data from the different experimental approaches were found to be generally consistent. In particular, for complex setups such as accelerator-based X-ray absorption spectroscopy, the agreement between the raw data was high. By contrast, luminescence spectroscopic data turned out to be strongly related to the chosen acquisition parameters. Second, the potentials and limitations of coupling various spectroscopic and theoretical approaches for the comprehensive study of actinide molecular complexes were assessed. Previous spectroscopic data from the literature were revised and the benchmark data on the U(VI) acetate system provided an unambiguous molecular interpretation based on the correlation of spectroscopic and theoretical results. The multimethodologic approach and the conclusions drawn address not only important aspects of actinide spectroscopy but particularly general aspects of modern molecular analytical chemistry.}, language = {en} } @article{FolmanKruegerSchmiedmayeretal.2002, author = {Folman, R. and Kr{\"u}ger, P. and Schmiedmayer, J{\"o}rg and Denschlag, J. H. and Henkel, Carsten}, title = {Microscopic atom optics : from wires to an atom chip}, year = {2002}, abstract = {We review the 10 year long journey into the miniaturization and integration of matter wave optics resulting in devices mounted on surfaces, so called atom chips. The first experiments started with the guiding of atoms with free standing wires and investigated the trapping potentials in simple geometries. Atom optical elements can now be micro fabricated down to 1 um size on atom chips. The creation of a Bose-Einstein condensate miniaturized in surface traps was recently achieved, and the first attempts to integrate light optics are in progress. In this review, we describe microscopic atom optics elements using current carrying and charged structures. Experiments with free standing structures (atom wires)are reviewed, investigating the basic principles of microscopic atom optics. We then discuss the miniaturization on the atom chip. One of the open central questions is dealt with: what happens with cold atoms close to a warm surface, how fast will they heat up or lose their coherence? The review concludes with an outlook of what we believe the future directions to be, and what can be hoped for.}, language = {en} } @article{ZhangHenkelHalleretal.2005, author = {Zhang, B. and Henkel, Carsten and Haller, E. and Wildermuth, S. and Hofferberth, S. and Kruger, P. and Schmiedmayer, J{\"o}rg}, title = {Relevance of sub-surface chip layers for the lifetime of magnetically trapped atoms}, year = {2005}, abstract = {We investigate the lifetime of magnetically trapped atoms above a planar, layered atom chip structure. Numerical calculations of the thermal magnetic noise spectrum are performed, based on the exact magnetic Green function and multi layer reflection coefficients. We have performed lifetime measurements where the center of a side guide trap is laterally shifted with respect to the current carrying wire using additional bias fields. Comparing the experiment to theory, we find a fair agreement and demonstrate that for a chip whose topmost layer is metallic, the magnetic noise depends essentially on the thickness of that layer, as long as the layers below have a, much smaller conductivity; essentially the same magnetic noise would be obtained with a metallic membrane suspended in vacuum. Based on our theory we give general scaling laws of how to reduce the effect of surface magnetic noise on the trapped atoms}, language = {en} } @article{HenkelKruegerFolmanetal.2003, author = {Henkel, Carsten and Kr{\"u}ger, P. and Folman, R. and Schmiedmayer, J{\"o}rg}, title = {Fundamental limits for coherent manipulation on atom chips}, issn = {0946-2171}, year = {2003}, language = {en} } @book{RodeGallinatHelmkeetal.1997, author = {Rode, J{\"u}rgen and Gallinat, Klaus and Helmke, Christa and Hoffmann, J{\"o}rg and Kr{\"u}ger, Detlef and Ohlert, Hans Henning and Wick, Ditmar and Ziezow, Ralf}, title = {Sportunterricht in der gymnasialen Oberstufe : themenorientierter Theorieunterricht im Fach Sport der Abiturstufe}, series = {Handreichungen / P{\"a}dagogisches Landesinstitut Brandenburg, Ludwigsfelden}, volume = {25}, journal = {Handreichungen / P{\"a}dagogisches Landesinstitut Brandenburg, Ludwigsfelden}, publisher = {Wissenschaft-und-Technik-Verl.}, address = {Berlin}, isbn = {3-89685-700-2}, pages = {59 S.}, year = {1997}, language = {de} } @book{KruegerBartel1994, author = {Kr{\"u}ger, Detlef and Bartel, J{\"o}rg}, title = {Sport und Spiel ein Leben lang! : eine Handreichung f{\"u}r den Aufbau von Seniorensportgruppen im Land Brandenburg ; zweiter Werkstattbericht aus dem Modellprojekt "Sport mit {\"A}lteren im Land Brandenburg"}, series = {ASuG-Materialien}, volume = {3}, journal = {ASuG-Materialien}, publisher = {Univ.}, address = {Potsdam}, pages = {76 S.}, year = {1994}, language = {de} } @article{SchmidtZiemannPentzienetal.2016, author = {Schmidt, Birgit Angelika and Ziemann, Martin Andreas and Pentzien, Simone and Gabsch, Toralf and Koch, Werner and Kr{\"u}ger, J{\"o}rg}, title = {Technical analysis of a Central Asian wall painting detached from a Buddhist cave temple on the northern Silk Road}, series = {Studies in Conservation}, volume = {61}, journal = {Studies in Conservation}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {0039-3630}, doi = {10.1179/2047058414Y.0000000152}, pages = {113 -- 122}, year = {2016}, abstract = {A great number of Central Asian wall paintings, archeological materials, architectural fragments, and textiles, as well as painting fragments on silk and paper, make up the so called Turfan Collection at the Asian Art Museum in Berlin. The largest part of the collection comes from the Kucha region, a very important cultural center in the third to ninth centuries. Between 1902 and 1914, four German expeditions traveled along the northern Silk Road. During these expeditions, wall paintings were detached from their original settings in Buddhist cave complexes. This paper reports a technical study of a wall painting, existing in eight fragments, from the Buddhist cave no. 40 (Ritterhohle). Its original painted surface is soot blackened and largely illegible. Gruwedel, leader of the first and third expeditions, described the almost complete destruction of the rediscovered temple complex and evidence of fire damage. The aim of this case study is to identify the materials used for the wall paintings. Furthermore, soot deposits as well as materials from conservation interventions were of interest. Non-invasive analyses were preferred but a limited number of samples were taken to provide more precise information on the painting technique. By employing optical and scanning electron microscopy, energy dispersive X-ray spectroscopy, micro X-ray fluorescence spectroscopy, X-ray diffraction analysis, and Raman spectroscopy, a layer sequence of earthen render, a ground layer made of gypsum, and a paint layer containing a variety of inorganic pigments were identified.}, language = {en} } @article{WeberWicksKruegeretal.1998, author = {Weber, Michael H. and Wicks, Chuck and Kr{\"u}ger, Frank and Jahnke, Gunnar and Schlittenhardt, J{\"o}rg}, title = {Asymmetric radiation of seismic waves from an atoll : nuclear tests in French Polynesia}, year = {1998}, language = {en} } @article{TscheuschnerKaiserLisecetal.2022, author = {Tscheuschner, Georg and Kaiser, Melanie N. and Lisec, Jan and Beslic, Denis and Muth, Thilo and Kr{\"u}ger, Maren and Mages, Hans Werner and Dorner, Brigitte G. and Knospe, Julia and Schenk, J{\"o}rg A. and Sellrie, Frank and Weller, Michael G.}, title = {MALDI-TOF-MS-based identification of monoclonal murine Anti-SARS-CoV-2 antibodies within one hour}, series = {Antibodies}, volume = {11}, journal = {Antibodies}, number = {2}, publisher = {MDPI}, address = {Basel}, issn = {2073-4468}, doi = {10.3390/antib11020027}, pages = {22}, year = {2022}, abstract = {During the SARS-CoV-2 pandemic, many virus-binding monoclonal antibodies have been developed for clinical and diagnostic purposes. This underlines the importance of antibodies as universal bioanalytical reagents. However, little attention is given to the reproducibility crisis that scientific studies are still facing to date. In a recent study, not even half of all research antibodies mentioned in publications could be identified at all. This should spark more efforts in the search for practical solutions for the traceability of antibodies. For this purpose, we used 35 monoclonal antibodies against SARS-CoV-2 to demonstrate how sequence-independent antibody identification can be achieved by simple means applied to the protein. First, we examined the intact and light chain masses of the antibodies relative to the reference material NIST-mAb 8671. Already half of the antibodies could be identified based solely on these two parameters. In addition, we developed two complementary peptide mass fingerprinting methods with MALDI-TOF-MS that can be performed in 60 min and had a combined sequence coverage of over 80\%. One method is based on the partial acidic hydrolysis of the protein by 5 mM of sulfuric acid at 99 degrees C. Furthermore, we established a fast way for a tryptic digest without an alkylation step. We were able to show that the distinction of clones is possible simply by a brief visual comparison of the mass spectra. In this work, two clones originating from the same immunization gave the same fingerprints. Later, a hybridoma sequencing confirmed the sequence identity of these sister clones. In order to automate the spectral comparison for larger libraries of antibodies, we developed the online software ABID 2.0. This open-source software determines the number of matching peptides in the fingerprint spectra. We propose that publications and other documents critically relying on monoclonal antibodies with unknown amino acid sequences should include at least one antibody fingerprint. By fingerprinting an antibody in question, its identity can be confirmed by comparison with a library spectrum at any time and context.}, language = {en} }