@misc{OzcelikayKurbanogluZhangetal.2019,
  author    = {Ozcelikay, Goksu and Kurbanoglu, Sevinc and Zhang, Xiaorong and S{\"o}z, {\c{C}}ağla Kosak and Wollenberger, Ulla and Ozkan, Sibel A. and Yarman, Aysu and Scheller, Frieder W.},
  title     = {Electrochemical MIP Sensor for Butyrylcholinesterase},
  series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  number    = {1138},
  issn      = {1866-8372},
  doi       = {10.25932/publishup-50185},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-501854},
  pages     = {13},
  year      = {2019},
  abstract  = {Molecularly imprinted polymers (MIPs) mimic the binding sites of antibodies by substituting the amino acid-scaffold of proteins by synthetic polymers. In this work, the first MIP for the recognition of the diagnostically relevant enzyme butyrylcholinesterase (BuChE) is presented. The MIP was prepared using electropolymerization of the functional monomer o-phenylenediamine and was deposited as a thin film on a glassy carbon electrode by oxidative potentiodynamic polymerization. Rebinding and removal of the template were detected by cyclic voltammetry using ferricyanide as a redox marker. Furthermore, the enzymatic activity of BuChE rebound to the MIP was measured via the anodic oxidation of thiocholine, the reaction product of butyrylthiocholine. The response was linear between 50 pM and 2 nM concentrations of BuChE with a detection limit of 14.7 pM. In addition to the high sensitivity for BuChE, the sensor responded towards pseudo-irreversible inhibitors in the lower mM range.},
  language  = {en}
}
@misc{YarmanScheller2014,
  author    = {Yarman, Aysu and Scheller, Frieder W.},
  title     = {The first electrochemical MIP sensor for tamoxifen},
  series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  number    = {1046},
  issn      = {1866-8372},
  doi       = {10.25932/publishup-47617},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-476173},
  pages     = {10},
  year      = {2014},
  abstract  = {We present an electrochemical MIP sensor for tamoxifen (TAM)-a nonsteroidal anti-estrogen-which is based on the electropolymerisation of an O-phenylenediamine. resorcinol mixture directly on the electrode surface in the presence of the template molecule. Up to now only. bulk. MIPs for TAM have been described in literature, which are applied for separation in chromatography columns. Electro-polymerisation of the monomers in the presence of TAM generated a film which completely suppressed the reduction of ferricyanide. Removal of the template gave a markedly increased ferricyanide signal, which was again suppressed after rebinding as expected for filling of the cavities by target binding. The decrease of the ferricyanide peak of the MIP electrode depended linearly on the TAM concentration between 1 and 100 nM. The TAM-imprinted electrode showed a 2.3 times higher recognition of the template molecule itself as compared to its metabolite 4-hydroxytamoxifen and no cross-reactivity with the anticancer drug doxorubucin was found. Measurements at + 1.1 V caused a fouling of the electrode surface, whilst pretreatment of TAM with peroxide in presence of HRP generated an oxidation product which was reducible at 0 mV, thus circumventing the polymer formation and electrochemical interferences.},
  language  = {en}
}
@article{BierKleinjungScheller1997,
  author    = {Bier, Frank Fabian and Kleinjung, Frank and Scheller, Frieder W.},
  title     = {Real time measurement of nucleic acid hybridization using evanescent wave sensors - step towards the genosensor},
  year      = {1997},
  language  = {en}
}
@article{EhrentreichFoersterSchellerBier2003,
  author    = {Ehrentreich-F{\"o}rster, Eva and Scheller, Frieder W. and Bier, Frank Fabian},
  title     = {Detection of progesterone in whole blood samples},
  year      = {2003},
  abstract  = {The progesterone concentration in blood samples can be utilised as a marker for the diagnosis of early pregnancy, endocrinopathy and virilism. Here, we describe a method for progesterone detection and measurement in whole blood samples by a surface sensitive biosensor used in conjunction with an integrated optical grating coupler. This device determines refractive index changes near the biosensor's surface. Hence, biological species bound to a surface layer can be measured in real-time without any label. For the measurements, we have modified the indirect competitive immonoassay principle. The concentration of the progesterone antibody was kept at 1 µg/ml. Progesterone concentration was determined in buffer solution and whole blood in a range between 0.005 and 10 ng/ml. The detection limit was determined to be 3 pM. The relative standard deviation was calculated to be 3.5\%.},
  language  = {en}
}
@article{SchellerBier2003,
  author    = {Scheller, Frieder W. and Bier, Frank Fabian},
  title     = {Biosensoren},
  year      = {2003},
  language  = {de}
}
@article{SchellerBier2004,
  author    = {Scheller, Frieder W. and Bier, Frank Fabian},
  title     = {Analytical Biochemistry (Editorial)},
  year      = {2004},
  language  = {en}
}
@article{SchellerBauerMakoweretal.2002,
  author    = {Scheller, Frieder W. and Bauer, Christian G. and Makower, Alexander and Wollenberger, Ursula and Warsinke, Axel and Bier, Frank Fabian},
  title     = {Immunoassays using enzymatic amplification electrodes},
  isbn      = {0-7484-0791-X},
  year      = {2002},
  language  = {en}
}
@article{KleinjungKlussmannErdmannetal.1998,
  author    = {Kleinjung, Frank and Klußmann, S. and Erdmann, V. A. and Scheller, Frieder W. and F{\"u}rste, J. P. and Bier, Frank Fabian},
  title     = {Novel binders in biosensorics : hight affinity RNA for smal analytes},
  year      = {1998},
  language  = {en}
}
@article{SchellerBauerMarkoweretal.2001,
  author    = {Scheller, Frieder W. and Bauer, Christian G. and Markower, Alexander and Wollenberger, Ursula and Warsinke, Axel and Bier, Frank Fabian},
  title     = {Coupling of immunoassays with enzymatic recycling electrodes},
  year      = {2001},
  language  = {en}
}
@article{SchmidtMatthesSchelleretal.2001,
  author    = {Schmidt, Peter Michael and Matthes, E. and Scheller, Frieder W. and Bier, Frank Fabian},
  title     = {Nachweis der Telomeraseaktivit{\"a}t in Zellkulturen mittels eines faseroptischen Sensors},
  year      = {2001},
  language  = {de}
}
@book{WollenbergerRennebergBieretal.2003,
  author    = {Wollenberger, Ursula and Renneberg, Reinhard and Bier, Frank Fabian and Scheller, Frieder W.},
  title     = {Analytische Biochemie : eine praktische Einf{\"u}hrung in das Messen mit Biomolek{\"u}len},
  publisher = {John Wiley \& Sons},
  address   = {Hoboken},
  isbn      = {3-527-30166-6},
  pages     = {222 S.},
  year      = {2003},
  language  = {de}
}
@article{SchellerBier2002,
  author    = {Scheller, Frieder W. and Bier, Frank Fabian},
  title     = {Trends in der Bioanalytik},
  year      = {2002},
  language  = {de}
}
@article{BierEhrentreichFoersterDoellingetal.1997,
  author    = {Bier, Frank Fabian and Ehrentreich-F{\"o}rster, Eva and D{\"o}lling, R. and Eremenko, A. V. and Scheller, Frieder W.},
  title     = {A redox-label immunosensor on basis of a bi-enzyme electrode},
  year      = {1997},
  language  = {en}
}
@article{MakowerBarminMorzunovaetal.1997,
  author    = {Makower, Alexander and Barmin, Anatoli V. and Morzunova, T. and Eremenko, Arkadi V. and Bier, Frank Fabian and Scheller, Frieder W.},
  title     = {Affinity enzymomoetric assay for detection of organophosphorus compounds},
  year      = {1997},
  language  = {en}
}
@article{BierEhrentreichFoersterScheller1996,
  author    = {Bier, Frank Fabian and Ehrentreich-F{\"o}rster, Eva and Scheller, Frieder W.},
  title     = {Amplifying bienzyme cycle-linked immunoassays for determination of 2,4- dichlorphenoxyacetic acid},
  year      = {1996},
  language  = {en}
}
@article{BierScheller1996,
  author    = {Bier, Frank Fabian and Scheller, Frieder W.},
  title     = {Label-free observation of DNA-hybridisation and endonuclease activity on a wave guide surface using a grating coupler},
  year      = {1996},
  language  = {en}
}
@article{StoeckleinMakowerBieretal.1997,
  author    = {St{\"o}cklein, Walter F. M. and Makower, Alexander and Bier, Frank Fabian and Scheller, Frieder W.},
  title     = {Enzyme sensors and enzyme amplifification systems},
  year      = {1997},
  language  = {en}
}
@article{BierFuersteKleinjungetal.1997,
  author    = {Bier, Frank Fabian and F{\"u}rste, J. P. and Kleinjung, Frank and Erdmann, V. A. and Scheller, Frieder W.},
  title     = {Nukleins{\"a}uren als Basis f{\"u}r Biosensoren},
  year      = {1997},
  language  = {de}
}
@article{SchellerBierGajovic1997,
  author    = {Scheller, Frieder W. and Bier, Frank Fabian and Gajovic, Nenad},
  title     = {Biosensoren und Teststreifen f{\"u}r die Umwelt- und Lebensmittelanalytik},
  year      = {1997},
  language  = {de}
}
@article{BierEhrentreichFoersterBaueretal.1996,
  author    = {Bier, Frank Fabian and Ehrentreich-F{\"o}rster, Eva and Bauer, Christian G. and Scheller, Frieder W.},
  title     = {High sensitive competitive immunodetection of 2,4-dichlorophenoxyacetic acid using enzymatic amplification with electrochemical detection},
  year      = {1996},
  language  = {en}
}
@article{BierEhrentreichFoersterSchelleretal.1996,
  author    = {Bier, Frank Fabian and Ehrentreich-F{\"o}rster, Eva and Scheller, Frieder W. and Makower, Alexander and Eremenko, A. V. and Wollenberger, Ursula and Bauer, Christian G. and Pfeiffer, Dorothea and Micheel, Burkhard},
  title     = {Ultrasensitive biosensors},
  year      = {1996},
  language  = {en}
}
@article{GhindilisMakowerBaueretal.1995,
  author    = {Ghindilis, A. L. and Makower, Alexander and Bauer, Christian G. and Bier, Frank Fabian and Scheller, Frieder W.},
  title     = {Determination of p-aminophenol and catecholamines at picomolar concentrations based on recycling enzyme amplification},
  year      = {1995},
  language  = {en}
}
@article{SchellerMakowerBieretal.1995,
  author    = {Scheller, Frieder W. and Makower, Alexander and Bier, Frank Fabian and Wollenberger, Ursula and Ghindilis, A. L. and Eremenko, A. V. and Pfeiffer, Dorothea},
  title     = {Enzymsensoren zur Bestimmung subnanomolarer Konzentrationen},
  year      = {1995},
  language  = {de}
}
@article{BierEhrentreichFoersterMakoweretal.1996,
  author    = {Bier, Frank Fabian and Ehrentreich-F{\"o}rster, Eva and Makower, Alexander and Scheller, Frieder W.},
  title     = {An enzymatic amplification cycle for high sensitive immunoassay},
  year      = {1996},
  language  = {en}
}
@article{SongBierScheller1995,
  author    = {Song, Min Ik and Bier, Frank Fabian and Scheller, Frieder W.},
  title     = {A method to detect superoxide radicals using teflon membrane and superoxide dismutase},
  year      = {1995},
  language  = {en}
}
@article{SchellerBierPfeiffer1995,
  author    = {Scheller, Frieder W. and Bier, Frank Fabian and Pfeiffer, Dorothea},
  title     = {Biosensoren : Grundlagen und Anwendungen},
  year      = {1995},
  language  = {de}
}
@article{SchellerMakowerGhindilisetal.1995,
  author    = {Scheller, Frieder W. and Makower, Alexander and Ghindilis, A. L. and Bier, Frank Fabian and Ehrentreich-F{\"o}rster, Eva and Wollenberger, Ursula and Bauer, Christian G. and Micheel, Burkhard and Pfeiffer, Dorothea and Szeponik, Jan and Michael, N. and Kaden, H.},
  title     = {Enzyme sensors for subnanomolar concentrations},
  year      = {1995},
  language  = {en}
}
@article{JinWollenbergerBieretal.1995,
  author    = {Jin, Wen and Wollenberger, Ursula and Bier, Frank Fabian and Scheller, Frieder W.},
  title     = {Construction and characterization of multi-layer-enzyme electrode : covalent binding of quinoprotein glucose dehydrogenase onto gold electrodes},
  year      = {1995},
  language  = {en}
}
@misc{BierYinKleinjungetal.1995,
  author    = {Bier, Frank Fabian and Yin, Wen and Kleinjung, Frank and Scheller, Frieder W.},
  title     = {Molekulare Schichten zur Analyse biochemischer Bindungen und Umsatzreaktionen},
  year      = {1995},
  language  = {de}
}
@article{KleinjungBierScheller1995,
  author    = {Kleinjung, Frank and Bier, Frank Fabian and Scheller, Frieder W.},
  title     = {Messungen an Nukleins{\"a}uren mittels evaneszenten Feldes},
  year      = {1995},
  language  = {de}
}
@article{BierSchellerKlingbeiletal.1993,
  author    = {Bier, Frank Fabian and Scheller, Frieder W. and Klingbeil, Mandy and Oßwald, U.},
  title     = {Biosensoren und Teststreifen f{\"u}r die Umwelt- und Lebensmittelanalytik : eine {\"U}bersicht},
  year      = {1993},
  language  = {de}
}
@article{SchellerBierNeumann1994,
  author    = {Scheller, Frieder W. and Bier, Frank Fabian and Neumann, B.},
  title     = {Bioindikation in aquatischen {\"O}kosystemen : Bioindikation in limnischen und k{\"u}stennahen {\"O}kosystemen ; Grundlagen, Verfahren und Methoden},
  publisher = {Fischer},
  address   = {Jena},
  pages     = {S. 380 - 386},
  year      = {1994},
  language  = {de}
}
@article{DechtriratGajovicEichelmannWojciketal.2014,
  author    = {Dechtrirat, Decha and Gajovic-Eichelmann, Nenad and Wojcik, Felix and Hartmann, Laura and Bier, Frank Fabian and Scheller, Frieder W.},
  title     = {Electrochemical displacement sensor based on ferrocene boronic acid tracer and immobilized glycan for saccharide binding proteins and E. coli},
  series = {Biosensors and bioelectronics : the principal international journal devoted to research, design development and application of biosensors and bioelectronics},
  volume    = {58},
  journal   = {Biosensors and bioelectronics : the principal international journal devoted to research, design development and application of biosensors and bioelectronics},
  publisher = {Elsevier},
  address   = {Oxford},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2014.02.028},
  pages     = {1 -- 8},
  year      = {2014},
  abstract  = {Pathogens such as viruses and bacteria use their envelope proteins and their adhesin lectins to recognize the glycan residues presented on the cell surface of the target tissues. This principle of recognition is used in a new electrochemical displacement sensor for the protein concanavalin A (ConA). A gold electrode was first modified with a self-assembled monolayer of a thiolated mannose/OEG conjugate and a ferrocene boroxol derivative was pre-assembled as reporter molecule onto the mannose surface. The novel tracer molecule based on a 2-hydroxymethyl phenyl boronic acid derivative binds even at neutral pH to the saccharides which could expand the application towards biological samples (i.e., urine and feces). Upon the binding of ConA, the tracer was displaced and washed away from the sensor surface leading to a decrease in the electrochemical signal. Using square wave voltammetry (SWV), the concentration of ConA in the sample solution could be determined in the dynamic concentration range established from 38 nmol L-1 to 5.76 mu mol L-1 with a reproducible detection limit of 1 mu g mL(-1) (38 nmol L-1) based on the signal-to-noise ratio (S/N=3) with fast response of 15 min. The new reporter molecule showed a reduced non-specific displacement by BSA and ribonuclease A. The sensor was also successfully transferred to the first proof of principle for the detection of Escherichia coli exhibiting a detection limit of approximately 6 x 102 cells/mL Specificity of the displacement by target protein ConA and E. coli was demonstrated since the control proteins (i.e., BSA and RNaseA) and the control E. coli strain, which lack of type 1 fimbriae, were ineffective. (C) 2014 Elsevier B.V. All rights reserved.},
  language  = {en}
}
@article{SchellerYarmanBachmannetal.2014,
  author    = {Scheller, Frieder W. and Yarman, Aysu and Bachmann, Till and Hirsch, Thomas and Kubick, Stefan and Renneberg, Reinhard and Schumacher, Soeren and Wollenberger, Ursula and Teller, Carsten and Bier, Frank Fabian},
  title     = {Future of biosensors: a personal view},
  series = {Advances in biochemical engineering, biotechnology},
  volume    = {140},
  journal   = {Advances in biochemical engineering, biotechnology},
  editor    = {Gu, MB and Kim, HS},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {978-3-642-54143-8; 978-3-642-54142-1},
  issn      = {0724-6145},
  doi       = {10.1007/10_2013_251},
  pages     = {1 -- 28},
  year      = {2014},
  abstract  = {Biosensors representing the technological counterpart of living senses have found routine application in amperometric enzyme electrodes for decentralized blood glucose measurement, interaction analysis by surface plasmon resonance in drug development, and to some extent DNA chips for expression analysis and enzyme polymorphisms. These technologies have already reached a highly advanced level and need minor improvement at most. The dream of the "100-dollar' personal genome may come true in the next few years provided that the technological hurdles of nanopore technology or of polymerase-based single molecule sequencing can be overcome. Tailor-made recognition elements for biosensors including membrane-bound enzymes and receptors will be prepared by cell-free protein synthesis. As alternatives for biological recognition elements, molecularly imprinted polymers (MIPs) have been created. They have the potential to substitute antibodies in biosensors and biochips for the measurement of low-molecular-weight substances, proteins, viruses, and living cells. They are more stable than proteins and can be produced in large amounts by chemical synthesis. Integration of nanomaterials, especially of graphene, could lead to new miniaturized biosensors with high sensitivity and ultrafast response. In the future individual therapy will include genetic profiling of isoenzymes and polymorphic forms of drug-metabolizing enzymes especially of the cytochrome P450 family. For defining the pharmacokinetics including the clearance of a given genotype enzyme electrodes will be a useful tool. For decentralized online patient control or the integration into everyday "consumables' such as drinking water, foods, hygienic articles, clothing, or for control of air conditioners in buildings and cars and swimming pools, a new generation of "autonomous' biosensors will emerge.},
  language  = {en}
}
@article{StoeckleinWarsinkeScheller1997,
  author    = {St{\"o}cklein, Walter F. M. and Warsinke, Axel and Scheller, Frieder W.},
  title     = {Organic solvent modified enzyme-liked immunoassay for the detection of triazine herbicides},
  year      = {1997},
  language  = {en}
}
@article{SchellerSchubertFederowitz1997,
  author    = {Scheller, Frieder W. and Schubert, Frank and Federowitz, J.},
  title     = {Present state and frontiers in biosensorics},
  year      = {1997},
  language  = {en}
}
@article{StoeckleinScheller1997,
  author    = {St{\"o}cklein, Walter F. M. and Scheller, Frieder W.},
  title     = {Enzymes and antibodies in organic media : analytical applications},
  year      = {1997},
  language  = {en}
}
@article{WollenbergerLisdatScheller1997,
  author    = {Wollenberger, Ursula and Lisdat, Fred and Scheller, Frieder W.},
  title     = {Enzymatic substrade recycling electrodes},
  year      = {1997},
  language  = {en}
}
@article{EremenkoMakowerBaueretal.1997,
  author    = {Eremenko, A. V. and Makower, Alexander and Bauer, Christian G. and Kurochkin, I. N. and Scheller, Frieder W.},
  title     = {A bienzyme electrode for tyrosine containing peptides determination},
  year      = {1997},
  language  = {en}
}
@article{XieTangWollenbergeretal.1997,
  author    = {Xie, B. and Tang, X. and Wollenberger, Ursula and Johansson, G. and Gorton, Lo and Scheller, Frieder W. and Danielsson, B.},
  title     = {Hybrid biosensor for simultaneous electrochemical and thermal detection},
  year      = {1997},
  language  = {en}
}
@article{EhrentreichFoersterSchellerMcNeil1997,
  author    = {Ehrentreich-F{\"o}rster, Eva and Scheller, Frieder W. and McNeil, C. J.},
  title     = {Biosensor zur in vivo Messung von Superoxidradikalen},
  year      = {1997},
  language  = {de}
}
@article{SzeponikMoellerPfeifferetal.1997,
  author    = {Szeponik, Jan and M{\"o}ller, B. and Pfeiffer, Dorothea and Lisdat, Fred and Wollenberger, Ursula and Makower, Alexander and Scheller, Frieder W.},
  title     = {Ultrasensitive bienzyme sensor for adrenaline},
  year      = {1997},
  language  = {en}
}
@article{MarkowerWollenbergerHoertnageletal.1997,
  author    = {Markower, Alexander and Wollenberger, Ursula and H{\"o}rtnagel, H. and Pfeiffer, Dorothea and Scheller, Frieder W.},
  title     = {Catecholamine detection using enzymatic amplification},
  year      = {1997},
  language  = {en}
}
@article{WelzelKossmehlEngelmannetal.1997,
  author    = {Welzel, H.-P. and Kossmehl, G. and Engelmann, G. and Neumann, B. and Wollenberger, Ursula and Scheller, Frieder W.},
  title     = {Electrochemical polymerization of functionalized thiohene derivatives for immobilization of proteins},
  year      = {1997},
  language  = {en}
}
@article{GajovicWarsinkeScheller1997,
  author    = {Gajovic, Nenad and Warsinke, Axel and Scheller, Frieder W.},
  title     = {Comparsion of two enzyme sequences for a novel L-malate biosensor},
  year      = {1997},
  language  = {en}
}
@article{KatterleWollenbergerScheller1997,
  author    = {Katterle, Martin and Wollenberger, Ursula and Scheller, Frieder W.},
  title     = {Electrochemistry of hemoglobin at modified silver electrodes is not a redox-process of iron protoporhyrin IX},
  year      = {1997},
  language  = {en}
}
@article{EhrentreichFoersterScheller1997,
  author    = {Ehrentreich-F{\"o}rster, Eva and Scheller, Frieder W.},
  title     = {Charakterisierung antioxidativer Substanzen mit einem Superoxidsensor},
  year      = {1997},
  language  = {de}
}
@article{KulysDrungilieneWollenbergeretal.1997,
  author    = {Kulys, J. and Drungiliene, A. and Wollenberger, Ursula and Krikstopaitis, K. and Scheller, Frieder W.},
  title     = {Electroanalytical determination of peroxidases and laccases on carbon paste electrodes},
  year      = {1997},
  language  = {en}
}
@article{KleinjungBeierWarsinkeetal.1997,
  author    = {Kleinjung, Frank and Beier, Frank F. and Warsinke, Axel and Scheller, Frieder W.},
  title     = {Fibre-optic genosensor for specific determination of femtomolar DNA oligomers},
  year      = {1997},
  language  = {en}
}
@article{PfeifferYangSchelleretal.1997,
  author    = {Pfeiffer, Dorothea and Yang, L. and Scheller, Frieder W. and Kissinger, P. T.},
  title     = {Continous measurement of lactate in microdialysate},
  year      = {1997},
  language  = {en}
}
@article{WollenbergerDrungilieneStoeckleinetal.1996,
  author    = {Wollenberger, Ursula and Drungiliene, A. and St{\"o}cklein, Walter F. M. and Kulys, J. and Scheller, Frieder W.},
  title     = {Direct electrocatalytic determination of dissolved peroxidases},
  year      = {1996},
  language  = {en}
}
@article{KaishevaIlievKazarevaetal.1996,
  author    = {Kaisheva, A. and Iliev, I. and Kazareva, R. and Christov, S. and Wollenberger, Ursula and Scheller, Frieder W.},
  title     = {Enzyme/gas diffusion electrodes for determination of phenol},
  year      = {1996},
  language  = {en}
}
@article{MakowerEremenkoStrefferetal.1996,
  author    = {Makower, Alexander and Eremenko, A. V. and Streffer, Katrin and Wollenberger, Ursula and Scheller, Frieder W.},
  title     = {Tyrosinase-glucose dehydrogenase substrate-recycling biosensor : a highly sensitive measurement of phenolic compounds},
  year      = {1996},
  language  = {en}
}
@article{SpricigoRichterLeimkuehleretal.2010,
  author    = {Spricigo, Roberto and Richter, Claudia and Leimk{\"u}hler, Silke and Gorton, Lo and Scheller, Frieder W. and Wollenberger, Ursula},
  title     = {Sulfite biosensor based on osmium redox polymer wired sulfite oxidase},
  issn      = {0927-7757},
  doi       = {10.1016/j.colsurfa.2009.09.001},
  year      = {2010},
  abstract  = {A biosensor, based on a redoxactive osmium polymer and sulfite oxidase on screen-printed electrodes, is presented here as a promising method for the detection of sulfite. A catalytic oxidative current was generated when a sample containing sulfite was pumped over the carbon screen-printed electrode modified with osmium redox polymer wired sulfite oxidase. A stationary value was reached after approximately 50 s and a complete measurement lasted no more than 3 min. The electrode polarized at -0.1 V (vs. Ag vertical bar AgCl 1M KCl) permits minimizing the influence of interfering substances, since these compounds can be unspecific oxidized at higher potentials. Because of the good stability of the protein film on the electrode surface, a well functioning biosensor-flow system was possible to construct. The working stability and reproducibility were further enhanced by the addition of bovine serum albumin generating a more long-term stable and biocompatible protein environment. The optimized biosensor showed a stable signal for more than a week of operation and a coefficient of variation of 4.8\% for 12 successive measurements. The lower limit of detection of the sensor was 0.5 mu M sulfite and the response was linear until 100 mu M. The high sensitivity permitted a 1:500 dilution of wine samples. The immobilization procedure and the operational conditions granted minimized interferences. Additionally, repeating the immobilization procedure to form several layers of wired SO further increased the sensitivity of such a sensor. Finally. the applicability of the developed sulfite biosensor was tested on real samples, such as white and red wines.},
  language  = {en}
}
@article{PfeifferSchellerMcNeiletal.1995,
  author    = {Pfeiffer, Dorothea and Scheller, Frieder W. and McNeil, C. J. and Schulmeister, Thomas},
  title     = {Cascade-like exponential substrate amplification in enzyme sensors},
  year      = {1995},
  language  = {en}
}
@article{PaeschkeHintscheWollenbergeretal.1995,
  author    = {Paeschke, Manfred and Hintsche, Rainer and Wollenberger, Ursula and Jin, Wen and Scheller, Frieder W.},
  title     = {Dynamic redox recycling of cytochrome c},
  issn      = {0022-0728},
  year      = {1995},
  language  = {en}
}
@article{SchellerPfeiffer1994,
  author    = {Scheller, Frieder W. and Pfeiffer, Dorothea},
  title     = {Biosensoren : ein wirtschaftlicher Faktor f{\"u}r die Zukunft},
  year      = {1994},
  language  = {de}
}
@article{Scheller1994,
  author    = {Scheller, Frieder W.},
  title     = {Biosensoren : Konzepte, Technologien, Perspektiven},
  year      = {1994},
  language  = {de}
}
@article{SchellerKirsteinPfeiffer1994,
  author    = {Scheller, Frieder W. and Kirstein, Dieter and Pfeiffer, Dorothea},
  title     = {Biosensoren, Konzepte, Technologien, Perspektiven},
  year      = {1994},
  language  = {de}
}
@article{SchellerHeiduschka1994,
  author    = {Scheller, Frieder W. and Heiduschka, P.},
  title     = {Preparation of an electrode surface with a high density of binding sites by an electrochemical reduction of a poly (nitrophenol) film},
  year      = {1994},
  language  = {en}
}
@article{SchmidScheller1994,
  author    = {Schmid, Rolf D. and Scheller, Frieder W.},
  title     = {Biosensoren},
  year      = {1994},
  language  = {de}
}
@article{LisdatDronovMoehwaldetal.2009,
  author    = {Lisdat, Fred and Dronov, Roman and M{\"o}hwald, Helmuth and Scheller, Frieder W. and Kurth, Dirk G.},
  title     = {Self-assembly of electro-active protein architectures on electrodes for the construction of biomimetic signal chains},
  issn      = {1359-7345},
  doi       = {10.1039/B813559b},
  year      = {2009},
  abstract  = {The layer-by-layer adsorption technique based on the consecutive deposition of oppositely charged species is for the preparation of protein multilayers with fully electro-active protein molecules. The methodology was established with cytochrome c and the polyelectrolyte sulfonated polyaniline (PASA). The technique is also useful for the construction of bi-protein architectures confining protein-protein communication to an electrode. Following natural examples of protein complexes with defined signal transfer, cytochrome c was arranged with enzymes such as xanthine oxidase, bilirubin oxidase, laccase, and sulfite oxidase in self-assembled multilayer architectures. Thus, biomimetic signal chains from the enzyme substrate via the enzyme and cytochrome c towards the electrode can be established. Communication between proteins immobilised in multiple layers on the electrode can be achieved by in situ generation of small shuttle molecules or more advantageously by direct interprotein electron transfer. This allows the construction of new sensing electrodes, the properties of which can be tuned by the number of deposited protein layers. The mechanism of electron transfer within such protein assemblies on gold electrodes will be discussed.},
  language  = {en}
}
@article{LoewWollenbergerSchelleretal.2009,
  author    = {Loew, Noya and Wollenberger, Ursula and Scheller, Frieder W. and Katterle, Martin},
  title     = {Direct electrochemistry and spectroelectrochemistry of osmium substituted horseradish peroxidase},
  issn      = {1567-5394},
  doi       = {10.1016/j.bioelechem.2009.03.015},
  year      = {2009},
  abstract  = {In this contribution the substitution of the central protoporphyrin IX iron complex of horseradish peroxidase by the respective osmium porphyrin complex is described. The direct electrochemical reduction of the Os containing horseradish peroxidase (OsHRP) was achieved at ITO and modified glassy carbon electrodes and in combination with spectroscopy revealed the three redox couples (OsHRP)-H-III/(OsHRP)-H-IV, (OsHRP)-H-IV/(OsHRP)-H-V and (OsHRP)-H-V/ (OsHRP)-H-VI. The midpoint potentials differ dependent on the electrode material used with E-1/2 (Os-III/IV) of -0.4 V (ITO) and -0.25 V (GC), E-1/2 (Os-IV/V) of -0.16 V (ITO) and +0.10 V (GC), and E-1/2 (Os-V/VI)of +018 V (ITO), respectively Moreover, with immobilised OsHRP the direct electrocatalytic reduction of hydrogen peroxide and tert-butyl hydroperoxide was observed. In comparison to electrodes modified with native HRP the sensitivity of the OsHRP-electrode for tert-butyl hydroperoxide is higher.},
  language  = {en}
}
@article{SchulmeisterScheller1996,
  author    = {Schulmeister, Thomas and Scheller, Frieder W.},
  title     = {The mathematics of exponential signal amplification in amperometric three enzyme electrodes},
  year      = {1996},
  language  = {en}
}
@article{StancikMacholanScheller1995,
  author    = {Stancik, L. and Machol{\´a}n, L. and Scheller, Frieder W.},
  title     = {Biosensing of tyrosinase inhibitors in nonaqueous solvents},
  year      = {1995},
  language  = {en}
}
@article{StoeckleinSchellerAbuknesha1995,
  author    = {St{\"o}cklein, Walter F. M. and Scheller, Frieder W. and Abuknesha, Rhamadan},
  title     = {Effects of organic solvents on semicontinuous immunochemical detection of coumarin derivatives},
  year      = {1995},
  language  = {en}
}
@article{StoeckleinScheller1995,
  author    = {St{\"o}cklein, Walter F. M. and Scheller, Frieder W.},
  title     = {Einsatz von Enzymen und Antik{\"o}rpern in organischen L{\"o}sungsmitteln},
  year      = {1995},
  language  = {de}
}
@article{WollenbergerHintscheScheller1995,
  author    = {Wollenberger, Ursula and Hintsche, R. and Scheller, Frieder W.},
  title     = {Biosensors for analytical microsystems},
  year      = {1995},
  language  = {en}
}
@article{EremenkoMakowerScheller1995,
  author    = {Eremenko, A. V. and Makower, Alexander and Scheller, Frieder W.},
  title     = {Measurement of nanomolar diphenols by substrate recycling coupled to a pH- sensitive electrode},
  year      = {1995},
  language  = {en}
}
@article{GajovicWarsinkeScheller1995,
  author    = {Gajovic, Nenad and Warsinke, Axel and Scheller, Frieder W.},
  title     = {A novel multienzyme electrode for the determination of citrate},
  year      = {1995},
  language  = {en}
}
@article{GhindilisMakowerScheller1995,
  author    = {Ghindilis, A. L. and Makower, Alexander and Scheller, Frieder W.},
  title     = {Laccase - glucose dehydrogenase recycling enzyme electrode based on potentiometric mediatorless electrocatalytic detection},
  year      = {1995},
  language  = {en}
}
@article{GhindilisMakowerScheller1995,
  author    = {Ghindilis, A. L. and Makower, Alexander and Scheller, Frieder W.},
  title     = {Nanomolar determination of the ferrocene derivatives using a recycling enzyme electrode : development of the redox label immunoassay},
  year      = {1995},
  language  = {en}
}
@article{GhindilisMakowerScheller1995,
  author    = {Ghindilis, A. L. and Makower, Alexander and Scheller, Frieder W.},
  title     = {Potentiometric enzyme electrodes based on substrate recycling and mediatorless bioelectrocatalysis},
  year      = {1995},
  language  = {en}
}
@article{LisdatWollenbergerPaeschkeetal.1998,
  author    = {Lisdat, Fred and Wollenberger, Ursula and Paeschke, Manfred and Scheller, Frieder W.},
  title     = {Sensitive catecholamine measurement using a monoenzymatic recycling system},
  year      = {1998},
  language  = {en}
}
@article{StancikMacholanPluhaceketal.1995,
  author    = {Stanc{\´i}k, L. and Machol{\´a}n, L. and Pluhacek, I. and Scheller, Frieder W.},
  title     = {Biosensing of rapeseed glucosinolates using amperometric enzyme electrodes based on membrane-bound glucose oxidase or tyrosinase},
  year      = {1995},
  language  = {en}
}
@article{EremenkoMakowerJinetal.1995,
  author    = {Eremenko, A. V. and Makower, Alexander and Jin, Wen and R{\"u}ger, P. and Scheller, Frieder W.},
  title     = {Biosensor based on an enzyme modified electrode for highly - sensitive measurement of polyphenols},
  year      = {1995},
  language  = {en}
}
@article{IlievKaishevaSchelleretal.1995,
  author    = {Iliev, I. and Kaisheva, A. and Scheller, Frieder W. and Pfeiffer, Dorothea},
  title     = {Amperometric gas-diffusion / enzyme electrode},
  year      = {1995},
  language  = {en}
}
@article{RiedelBeyersdorfRadeckNeumannetal.1995,
  author    = {Riedel, K. and Beyersdorf-Radeck, Baerbel and Neumann, B. and Scheller, Frieder W. and Schmid, Rolf D.},
  title     = {Microbial sensors for determination of aromatics and their chloro derivatives. Part III: Determination of chlorinated phenols using a biosensor containing Trichosporon beigelii (cutaneum)},
  year      = {1995},
  language  = {en}
}
@article{ShumyantsevaIvanovBistolasetal.2004,
  author    = {Shumyantseva, V. V. and Ivanov, Y. D. and Bistolas, Nikitas and Scheller, Frieder W. and Archakov, Alexander I. and Wollenberger, Ursula},
  title     = {Direct electron transfer of cytochrome P450 2B4 at electrodes modified with non-ionic detergent and colloidal clay nanoparticles},
  year      = {2004},
  abstract  = {A method for construction of biosensors with membranous cytochrome P450 isoenzymes was developed based on clay/ detergent/protein mixed films. Thin films of sodium montmorillonite colloid with incorporated cytochrome P450 2134 (CYP2B4) with nonionic detergent were prepared on glassy carbon electrodes. The modified electrodes were electrochemically characterized, and bio-electrocatalytic reactions were followed. CYP2B4 can be reduced fast on clay- modified glassy carbon electrodes in the presence of the nonionic detergent Tween 80. In anaerobic solutions, reversible oxidation and reduction is obtained with a formal potential between -0.292 and - 0.305 V vs Ag/AgCl 1 M KCl depending on the preparation of the biosensor. In air-saturated solution, bio-electrocatalytic reduction currents can be obtained with the CYP2B4-modified electrode on addition of typical substrates such as aminopyrine and benzphetamine. This reaction was suppressed when methyrapone, an inhibitor of P450 reactions, was present. Measurement of product formation also indicates the bioelectrocatialysis by CYP2B4},
  language  = {en}
}
@article{FrascavonGrabergFengetal.2010,
  author    = {Frasca, Stefano and von Graberg, Till and Feng, Jiu-Ju and Thomas, Arne and Smarsly, Bernd M. and Weidinger, Inez M. and Scheller, Frieder W. and Hildebrandt, Peter and Wollenberger, Ursula},
  title     = {Mesoporous indium tin oxide as a novel platform for bioelectronics},
  issn      = {1867-3880},
  doi       = {10.1002/cctc.201000047},
  year      = {2010},
  abstract  = {Stable immobilization and reversible electrochemistry of cytochrome c in a tranparent indium tin oxide film with a well-defined mesoporosity (mpITO) is demonstrated. the transparency and good conductivity, in combination with the large surface area of mpITO, allow the incorporation of a high amount of elelctroactive biomolecules and their electrochemical and spectroscopic investigation. UV/Vis and resonance Raman spectroscopy, in combination with direct protein voltammetry are employed for the characterization of cytochrome c immobilized in the mpITO and reveal no perturbant of the structural of the integrity of the redox protein. The potential of this modified material as a biosensor detection of superoxide anions is also demonstrated.},
  language  = {en}
}
@article{StoeckleinWarsinkeMicheeletal.1998,
  author    = {St{\"o}cklein, Walter F. M. and Warsinke, Axel and Micheel, Burkhard and H{\"o}hne, Wolfgang and Woller, Jochen and Kempter, Gerhard and Scheller, Frieder W.},
  title     = {Characterization of a monoclonal antibody and its Fab fragment against diphenylurea hapten with BIA},
  isbn      = {3-8154-3540-4},
  year      = {1998},
  language  = {en}
}
@article{WarsinkeStancikMacholanetal.1998,
  author    = {Warsinke, Axel and Stancik, L. and Machol{\´a}n, L. and Pfeiffer, Dorothea and Scheller, Frieder W.},
  title     = {Biosensors for food analysis : application of biosensors to food requirements},
  isbn      = {0-85404-750-6},
  year      = {1998},
  language  = {en}
}
@article{StoeckleinWarsinkeMicheeletal.1997,
  author    = {St{\"o}cklein, Walter F. M. and Warsinke, Axel and Micheel, Burkhard and H{\"o}hne, Wolfgang and Woller, Jochen and Kempter, Gerhard and Scheller, Frieder W.},
  title     = {Detection of diphenylurea derivatives with biospecific interaction analysis (BIA) : Kinetic investigations},
  year      = {1997},
  language  = {en}
}
@article{SpricigoDronovLisdatetal.2009,
  author    = {Spricigo, Roberto and Dronov, Roman and Lisdat, Fred and Leimk{\"u}hler, Silke and Scheller, Frieder W. and Wollenberger, Ursula},
  title     = {Electrocatalytic sulfite biosensor with human sulfite oxidase co-immobilized with cytochrome c in a polyelectrolyte-containing multilayer},
  issn      = {1618-2642},
  doi       = {10.1007/s00216-008-2432-y},
  year      = {2009},
  abstract  = {An efficient electrocatalytic biosensor for sulfite detection was developed by co-immobilizing sulfite oxidase and cytochrome c with polyaniline sulfonic acid in a layer-by-layer assembly. QCM, UV-Vis spectroscopy and cyclic voltammetry revealed increasing loading of electrochemically active protein with the formation of multilayers. The sensor operates reagentless at low working potential. A catalytic oxidation current was detected in the presence of sulfite at the modified gold electrode, polarized at +0.1 V ( vs. Ag/AgCl 1 M KCl). The stability of the biosensor performance was characterized and optimized. A 17-bilayer electrode has a linear range between 1 and 60 mu M sulfite with a sensitivity of 2.19 mA M-1 sulfite and a response time of 2 min. The electrode retained a stable response for 3 days with a serial reproducibility of 3.8\% and lost 20\% of sensitivity after 5 days of operation. It is possible to store the sensor in a dry state for more than 2 months. The multilayer electrode was used for determination of sulfite in unspiked and spiked samples of red and white wine. The recovery and the specificity of the signals were evaluated for each sample.},
  language  = {en}
}
@article{EhrentreichFoersterShishniashviliSongetal.1998,
  author    = {Ehrentreich-F{\"o}rster, Eva and Shishniashvili, D. and Song, Min Ik and Scheller, Frieder W.},
  title     = {Study of antioxidative substances by means of a ssuperoxide sensor},
  year      = {1998},
  language  = {en}
}
@article{KulysDrungilieneWollenbergeretal.1998,
  author    = {Kulys, J. and Drungiliene, A. and Wollenberger, Ursula and Scheller, Frieder W.},
  title     = {Membrane covered carbon paste electrode for the electrochemical determination of perioxidase and microperoxidase in a flow system},
  year      = {1998},
  language  = {en}
}
@article{JinBernhardtStoeckleinetal.1998,
  author    = {Jin, Wen and Bernhardt, Rita and St{\"o}cklein, Walter F. M. and Scheller, Frieder W.},
  title     = {Direct electron transfer of adrenodoxin-a [2Fe-2S] protein-- and its mutants on modified gold electrode},
  year      = {1998},
  language  = {en}
}
@article{WollenbergerNeumannScheller1998,
  author    = {Wollenberger, Ursula and Neumann, B. and Scheller, Frieder W.},
  title     = {Development of a biomimetic alkane sensor f},
  year      = {1998},
  language  = {en}
}
@article{Scheller1998,
  author    = {Scheller, Frieder W.},
  title     = {Biosensorik},
  year      = {1998},
  language  = {de}
}
@article{SchellerPfeifferLisdatetal.1998,
  author    = {Scheller, Frieder W. and Pfeiffer, Dorothea and Lisdat, Fred and Bauer, Christian G. and Gajovic, Nenad},
  title     = {Enzyme biosensors based on oxygen detection},
  year      = {1998},
  language  = {en}
}
@article{BogdanovskayaFridmanTarasevichetal.1994,
  author    = {Bogdanovskaya, V. A. and Fridman, Vadim and Tarasevich, M. R. and Scheller, Frieder W.},
  title     = {Bioelectrocatalysis by immobilized peroxidase : the reaction mechanism and the possibility of electroanalytical detection of both inhibitors and activators of enzyme},
  year      = {1994},
  language  = {en}
}
@article{KirsteinKirsteinSchelleretal.1994,
  author    = {Kirstein, Dieter and Kirstein, Lincoln and Scheller, Frieder W. and Dieckmann, St. and Ronnenberg, J. and Beckmann, Dieter and Weckenbrock, E.},
  title     = {Elektroenzymatische Reduktion von Nitrat},
  year      = {1994},
  language  = {de}
}
@article{WollenbergerNeumannRiedeletal.1994,
  author    = {Wollenberger, Ursula and Neumann, B. and Riedel, K. and Scheller, Frieder W.},
  title     = {Enzyme and microbial sensors for phosphate, phenols, pesticides and peroxides},
  year      = {1994},
  language  = {en}
}
@article{YarmanScheller2013,
  author    = {Yarman, Aysu and Scheller, Frieder W.},
  title     = {Coupling biocatalysis with molecular imprinting in a biomimetic sensor},
  series = {Angewandte Chemie : a journal of the Gesellschaft Deutscher Chemiker ; International edition},
  volume    = {52},
  journal   = {Angewandte Chemie : a journal of the Gesellschaft Deutscher Chemiker ; International edition},
  number    = {44},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1433-7851},
  doi       = {10.1002/anie.201305368},
  pages     = {11521 -- 11525},
  year      = {2013},
  language  = {en}
}
@article{SchellerPfeiffer1997,
  author    = {Scheller, Frieder W. and Pfeiffer, Dorothea},
  title     = {Commercial devices based on amperometric biosensors},
  year      = {1997},
  language  = {en}
}
@article{SchulmeisterRoseScheller1997,
  author    = {Schulmeister, Thomas and Rose, J{\"u}rgen and Scheller, Frieder W.},
  title     = {Mathematical modelling of exponential amplification in membrane-based enzyme sensors},
  year      = {1997},
  language  = {en}
}
@article{WarsinkeBenkertScheller1996,
  author    = {Warsinke, Axel and Benkert, Alexander and Scheller, Frieder W.},
  title     = {Biomolecular modules for creatinine determination},
  year      = {1996},
  language  = {en}
}
@article{StoeckleinScheller1996,
  author    = {St{\"o}cklein, Walter F. M. and Scheller, Frieder W.},
  title     = {Laccase : a marker enzyme for solvent modified immunoassays},
  year      = {1996},
  language  = {en}
}
@article{HalamekWollenbergerStoeckleinetal.2007,
  author    = {Hal{\´a}mek, Jan and Wollenberger, Ursula and St{\"o}cklein, Walter F. M. and Scheller, Frieder W.},
  title     = {Development of a biosensor for glycated hemoglobin},
  issn      = {0013-4686},
  doi       = {10.1016/j.electacta.2007.03.059},
  year      = {2007},
  abstract  = {The development of an electrochemical piezoelectric sensor for the detection of glycated hemoglobin is presented. The total hemoglobin (Hb) content is monitored with a mass-sensitive quartz crystal modified with surfactants, and the glycated fraction of the immobilized Hb is determined by subsequent voltarnmetric measurement of the coupled ferroceneboronic acid. Different modifications of the sensor were tested for their hemoglobin binding ability. Deoxycholate (DOCA) was found to be the most suitable among the examined modifiers. Piezoelectric quartz crystals with gold electrodes were modified with DOCA by covalent binding to a pre-formatted 4-aminothiophenol monolayer. The properties of the Hb binding to DOCA and the pH effect on this interaction were studied. In the proposed assay for glycated hemoglobin at first an Hb sample is incubated with ferroceneboronic acid (FcBA), which binds to the fructosyl residue of the glycated Hb. Then this preincubated Hb sample is allowed to interact with the DOCA-modified piezoelectric quartz crystal. The binding is monitored by quartz crystal nanobalance QCN). The amount of FcBA present on the sensor surface is determined by square wave voltammetry. The binding of FcBA results in well-defined peaks with an EO' of +200 mV versus Ag/AgC1 (1 M KC1). The peak height depends on the degree of glycated Hb in the sample ranging from 0\% to 20\% of total Hb. The regeneration of the sensing surface is achieved by pepsin digestion of the deposited Hb. Thus the sensor can be re-used more than 30 times.},
  language  = {en}
}
@article{HalamekWollenbergerStoeckleinetal.2007,
  author    = {Hal{\´a}mek, Jan and Wollenberger, Ursula and St{\"o}cklein, Walter F. M. and Warsinke, Axel and Scheller, Frieder W.},
  title     = {Signal amplification in immunoassays using labeling via boronic acid binding to the sugar moiety of immunoglobulin G : proof of concept for glycated hemoglobin},
  issn      = {0003-2719},
  doi       = {10.1080/00032710701327096},
  year      = {2007},
  abstract  = {A novel electrochemical immunoassay based on the multiple affinity labeling of the indicator antibody with an electro-active tag is presented. The concept is illustrated for the determination of the glycated hemoglobin HbA1c in hemoglobin samples. Hemoglobin is adsorbed to the surfactant-modified surface of a piezoelectric quartz crystal. Whereas the quartz crystal nanobalance is used to validate the total Hb binding, the HbA1c on the sensor surface is recognized by an antibody and quantified electrochemically after the sugar moieties of the antibody have been labeled in-situ with ferroceneboronic acid. The sensitivity of this sensor is about threefold higher than the sensitivity of a hemoglobin sensor, where the ferroceneboronic acid is bound directly to HbA1c.},
  language  = {en}
}