@inproceedings{BorowskiGlowinskiFristeretal.2018, author = {Borowski, Andreas and Glowinski, Ingrid and Frister, Jonas and H{\"o}ttecke, Dietmar and Buth, Katrin and Koenen, Jenna and Masanek, Nicole and Reichwein, Wilko and Scholten, Nina and Sprenger, Sandra and Stender, Peter and W{\"o}hlke, Carina and Komorek, Michael and Freckmann, Janine and Hofmann, Josefine and Niesel, Verena and Richter, Chris and Mehlmann, Nelli and Bikner-Ahsbahs, Angelika and Unverricht, Katja and Schanze, Sascha and Bittorf, Robert Marten and Meier, Monique and Grospietsch, Finja and Mayer, J{\"u}rgen and Gimbel, Katharina and Ziepprecht, Kathrin and Hofmann, Judith and Kramer, Charlotte and M{\"u}ller, Britta-Kornelia and Rohde, Andreas and Z{\"u}hlsdorf, Felix and Winkler, Iris and Laging, Ralf and Peter, Carina and Schween, Michael and H{\"a}rle, Gerhard and Busse, Beatrix and Mahner, Sebastian and K{\"o}stler, Verena and Kufner, Sabrina and M{\"a}gdefrau, Jutta and M{\"u}ller, Christian and Beck, Christina and Kriehuber, Eva and Boch, Florian and Engl, Anna-Teresa and Helzel, Andreas and Pickert, Tina and Reiter, Christian and Blasini, Bettina and Nerdel, Claudia and Lewalter, Doris and Schiffhauer, Silke and Richter-Gebert, J{\"u}rgen and Bannert, Maria and Maahs, Mirjam and Reißner, Maria and Ungar, Patrizia and von Wachter, Jana-Kristin and Hellmann, Katharina and Zaki, Katja and Pohlenz, Philipp}, title = {Koh{\"a}renz in der universit{\"a}ren Lehrerbildung}, editor = {Glowinski, Ingrid and Borowski, Andreas and Gillen, Julia and Schanze, Sascha and von Meien, Joachim}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-438-8}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-414267}, year = {2018}, abstract = {One area that is supported by the project "Qualit{\"a}tsoffensive Lehrerbildung" (funded by BMBF) is the improvement of collaboration and coordination between studies in the discipline, studies in pedagogical content knowledge, and studies in pedagogical knowledge during teacher education at university. Aiming a better coordination among these three parts of teacher education at university, many of the supported projects have designed and realized university-specific approaches. This conference proceedings volume comprises contributions by 15 of these projects. Seven of those were introduced and discussed in workshops on the occasion of two cross-regional project-conferences in Hannover and Potsdam. Overall, the contributions give a theoretically funded as well as a practice-oriented overview of current approaches and concepts to achieve a better connection between study units concerning studies in content knowledge, pedagogical content knowledge and pedagogical knowledge in teacher education. The volume presents university projects, which take effect on different levels (at the level of curriculum and content, at a collegiate level, at the level of structural conditions of universities). The different approaches are described in a way that they can provide a basis for transfer to other subjects or further universities. The contributions are aimed at teacher educators as well as other actors working in the field of teaching- and quality development at universities. All of them can take transferable ideas and impulses from the described concepts and formats.}, language = {de} } @article{RichterFoxWakkeretal.2018, author = {Richter, Philipp and Fox, Andrew J. and Wakker, Bart P. and Howk, J. Christopher and Lehner, Nicolas and Barger, Kathleen A. and Lockman, Felix J.}, title = {New constraints on the nature and origin of the leading arm of the magellanic stream}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, volume = {865}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, number = {2}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {0004-637X}, doi = {10.3847/1538-4357/aadd0f}, pages = {16}, year = {2018}, abstract = {We present a new precision measurement of gas-phase abundances of S, O, N, Si, Fe, P, Al, Ca as well as molecular hydrogen (H-2) in the Leading Arm (region II, LA II) of the Magellanic Stream (MS) toward the Seyfert galaxy NGC 3783. The results are based on high-quality archival ultraviolet/optical/radio data from various different instruments (HST/STIS, FUSE, AAT, GBT, GB140 ft, ATCA). Our study updates previous results from lower-resolution data and provides for the first time a self-consistent component model of the complex multiphase absorber, delivering important constraints on the nature and origin of LA II. We derive a uniform, moderate a abundance in the two main absorber groups at +245 and +190 km s(-1) of alpha/H = 0.30 +/- 0.05 solar, a low nitrogen abundance of N/H = 0.05 +/- 0.01 solar, and a high dust content with substantial dust depletion values for Si, Fe, Al, and Ca. These a, N, and dust abundances in LA II are similar to those observed in the Small Magellanic Cloud (SMC). From the analysis of the H2 absorption, we determine a high thermal pressure of P/k approximate to 1680 K cm(-3) in LA II, in line with the idea that LA II is located in the inner Milky Way halo at a z-height of < 20 kpc, where it hydrodynamically interacts with the ambient hot coronal gas. Our study supports a scenario in which LA II stems from the breakup of a metal- and dust-enriched progenitor cloud that was recently (200-500 Myr ago) stripped from the SMC.}, language = {en} } @article{FoxBargerWakkeretal.2018, author = {Fox, Andrew J. and Barger, Kathleen A. and Wakker, Bart P. and Richter, Philipp and Antwi-Danso, Jacqueline and Casetti-Dinescu, Dana I. and Howk, J. Christopher and Lehner, Nicolas and Crowther, Paul A. and Lockman, Felix J.}, title = {Chemical Abundances in the Leading Arm of the Magellanic Stream}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, volume = {854}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, number = {2}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {0004-637X}, doi = {10.3847/1538-4357/aaa9bb}, pages = {14}, year = {2018}, abstract = {The Leading Arm (LA) of the Magellanic Stream is a vast debris field of H I clouds connecting the Milky Way and the Magellanic Clouds. It represents an example of active gas accretion onto the Galaxy. Previously, only one chemical abundance measurement had been made in the LA. Here we present chemical abundance measurements using Hubble Space Telescope/Cosmic Origins Spectrograph and Green Bank Telescope spectra of four AGN sightlines passing through the LA and three nearby sightlines that may trace outer fragments of the LA. We find low oxygen abundances, ranging from 4.0+(2.0)(2.0)\% 12.6(4.1)(6.0)\% solar, in the confirmed LA directions, with the lowest values found in the region known as LA III, farthest from the LMC. These abundances are substantially lower than the single previous measurement, S/H = 35 +/- 7\% solar, but are in agreement with those reported in the SMC filament of the trailing Stream, supporting a common origin in the SMC (not the LMC) for the majority of the LA and trailing Stream. This provides important constraints for models of the formation of the Magellanic System. Finally, two of the three nearby sightlines show high-velocity clouds with H I columns, kinematics, and oxygen abundances consistent with LA membership. This suggests that the LA is larger than traditionally thought, extending at least 20 degrees further to the Galactic northwest.}, language = {en} } @article{AbdallaAbramowskiAharonianetal.2017, author = {Abdalla, Hassan E. and Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Akhperjanian, A. G. and Andersson, T. and Anguner, Ekrem Oǧuzhan and Arakawa, M. and Arrieta, M. and Aubert, Pierre and Backes, Michael and Balzer, Arnim and Barnard, Michelle and Becherini, Yvonne and Tjus, J. Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Blackwell, R. and B{\"o}ttcher, Markus and Boisson, Catherine and Bolmont, J. and Bonnefoy, S. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Buechele, M. and Bulik, Tomasz and Capasso, M. and Carr, John and Casanova, Sabrina and Cerruti, M. and Chakraborty, N. and Chaves, Ryan C. G. and Chen, Andrew and Chevalier, J. and Coffaro, M. and Colafrancesco, Sergio and Cologna, Gabriele and Condon, B. and Conrad, Jan and Cui, Y. and Davids, I. D. and Decock, J. and Degrange, B. and Deil, C. and Devin, J. and de Wilt, P. and Dirson, L. and Djannati-Atai, A. and Domainko, W. and Donath, A. and Dutson, K. and Dyks, J. and Edwards, T. and Egberts, Kathrin and Eger, P. and Ernenwein, J. -P. and Eschbach, S. and Farnier, C. and Fegan, S. and Fernandes, M. V. and Fiasson, A. and Fontaine, G. and Foerster, A. and Funk, S. and Fuessling, M. and Gabici, S. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Goyal, A. and Grondin, M. -H. and Hahn, J. and Haupt, M. and Hawkes, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hinton, James Anthony and Hofmann, W. and Hoischen, Clemens and Holch, Tim Lukas and Holler, M. and Horns, D. and Ivascenko, A. and Iwasaki, H. and Jacholkowska, A. and Jamrozy, M. and Janiak, M. and Jankowsky, D. and Jankowsky, F. and Jingo, M. and Jogler, T. and Jouvin, L. and Jung-Richardt, I. and Kastendieck, M. A. and Katarzynski, K. and Katsuragawa, M. and Katz, U. and Kerszberg, D. and Khangulyan, D. and Khelifi, B. and King, J. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Kraus, M. and Kruger, P. P. and Laffon, H. and Lamanna, G. and Lau, J. and Lees, J. -P. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Leser, Eva and Lohse, T. and Lorentz, M. and Liu, R. and Lopez-Coto, R. and Lypova, I. and Marandon, V. and Marcowith, Alexandre and Mariaud, C. and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and Meintjes, P. J. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mohrmann, L. and Mora, K. and Moulin, Emmanuel and Murach, T. and Nakashima, S. and de Naurois, M. and Niederwanger, F. and Niemiec, J. and Oakes, L. and Odaka, H. and Ohm, S. and Ostrowski, M. and Oya, I. and Padovani, M. and Panter, M. and Parsons, R. D. and Pekeur, N. W. and Pelletier, G. and Perennes, C. and Petrucci, P. -O. and Peyaud, B. and Piel, Q. and Pita, S. and Poon, H. and Prokhorov, D. and Prokoph, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Rauth, R. and Reimer, A. and Reimer, O. and Renaud, M. and de los Reyes, R. and Richter, S. and Rieger, F. and Romoli, C. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Saito, S. and Salek, D. and Sanchez, David M. and Santangelo, Andrea and Sasaki, M. and Schlickeiser, R. and Schussler, F. and Schulz, A. and Schwanke, U. and Schwemmer, S. and Seglar-Arroyo, M. and Settimo, M. and Seyffert, A. S. and Shafi, N. and Shilon, I. and Simoni, R. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stycz, K. and Sushch, Iurii and Takahashi, T. and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tibaldo, L. and Tiziani, D. and Tluczykont, M. and Trichard, C. and Tsuji, N. and Tuffs, R. and Uchiyama, Y. and van der Walt, D. J. and van Eldik, C. and van Rensburg, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voisin, F. and Voelk, H. J. and Vuillaume, T. and Wadiasingh, Z. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zaborov, D. and Zacharias, M. and Zanin, R. and Zdziarski, A. A. and Zech, Alraune and Zefi, F. and Ziegler, A. and Zywucka, N.}, title = {Measurement of the EBL spectral energy distribution using the VHE gamma-ray spectra of HESS blazars}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {606}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, organization = {HESS Collaboration}, issn = {1432-0746}, doi = {10.1051/0004-6361/201731200}, pages = {11}, year = {2017}, abstract = {Very high-energy gamma rays (VHE, E greater than or similar to 100 GeV) propagating over cosmological distances can interact with the low-energy photons of the extragalactic background light (EBL) and produce electron-positron pairs. The transparency of the Universe to VHE gamma rays is then directly related to the spectral energy distribution (SED) of the EBL. The observation of features in the VHE energy spectra of extragalactic sources allows the EBL to be measured, which otherwise is very difficult. An EBL model-independent measurement of the EBL SED with the H.E.S.S. array of Cherenkov telescopes is presented. It was obtained by extracting the EBL absorption signal from the reanalysis of high-quality spectra of blazars. From H.E.S.S. data alone the EBL signature is detected at a significance of 9.5 sigma, and the intensity of the EBL obtained in different spectral bands is presented together with the associated gamma-ray horizon.}, language = {en} } @article{AbdallaAbramowskiAharonianetal.2018, author = {Abdalla, Hassan E. and Abramowski, A. and Aharonian, Felix A. and Benkhali, F. Ait and Akhperjanian, A. G. and Andersson, T. and Anguener, E. O. and Arakawa, M. and Arrieta, M. and Aubert, P. and Backes, M. and Balzer, A. and Barnard, M. and Becherini, Y. and Tjus, J. Becker and Berge, D. and Bernhard, S. and Bernloehr, K. and Blackwell, R. and Boettcher, M. and Boisson, C. and Bolmont, J. and Bonnefoy, S. and Bordas, Pol and Bregeon, J. and Brun, F. and Brun, P. and Bryan, M. and Buechele, M. and Bulik, T. and Capasso, M. and Carr, J. and Casanova, Sabrina and Cerruti, M. and Chakraborty, N. and Chaves, R. C. G. and Chen, A. and Chevalier, J. and Coffaro, M. and Colafrancesco, S. and Cologna, G. and Condon, B. and Conrad, J. and Cui, Y. and Davids, I. D. and Decock, J. and Degrange, B. and Deil, C. and Devin, J. and deWilt, P. and Dirson, L. and Djannati-Atai, A. and Domainko, W. and Donath, A. and Dutson, K. and Dyks, J. and Edwards, T. and Egberts, Kathrin and Eger, P. and Ernenwein, J. -P. and Eschbach, S. and Farnier, C. and Fegan, S. and Fernandes, M. V. and Fiasson, A. and Fontaine, G. and Foerster, A. and Funk, S. and Fuessling, M. and Gabici, S. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Goyal, A. and Grondin, M. -H. and Hahn, J. and Haupt, M. and Hawkes, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hinton, J. A. and Hofmann, W. and Hoischen, Clemens and Holch, T. L. and Holler, M. and Horns, D. and Ivascenko, A. and Iwasaki, H. and Jacholkowska, A. and Jamrozy, M. and Janiak, M. and Jankowsky, D. and Jankowsky, F. and Jingo, M. and Jogler, T. and Jouvin, L. and Jung-Richardt, I. and Kastendieck, M. A. and Katarzynski, K. and Katsuragawa, M. and Katz, U. and Kerszberg, D. and Khangulyan, D. and Khelifi, B. and King, J. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Kraus, M. and Krueger, P. P. and Laffon, H. and Lamanna, G. and Lau, J. and Lees, J. -P. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Leser, Eva and Lohse, T. and Lorentz, M. and Liu, R. and Lopez-Coto, R. and Lypova, I. and Marandon, V. and Marcowith, Alexandre and Mariaud, C. and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and Meintjes, P. J. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mohrmann, L. and Mora, K. and Moulin, Emmanuel and Murach, T. and Nakashima, S. and de Naurois, M. and Niederwanger, F. and Niemiec, J. and Oakes, L. and Odaka, H. and Ohm, S. and Ostrowski, M. and Oya, I. and Padovani, M. and Panter, M. and Parsons, R. D. and Pekeur, N. W. and Pelletier, G. and Perennes, C. and Petrucci, P. -O. and Peyaud, B. and Piel, Q. and Pita, S. and Poon, H. and Prokhorov, D. and Prokoph, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Rauth, R. and Reimer, A. and Reimer, O. and Renaud, M. and de los Reyes, R. and Richter, S. and Rieger, F. and Romoli, C. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Saito, S. and Salek, D. and Sanchez, D. A. and Santangelo, Andrea and Sasaki, M. and Schlickeiser, R. and Schuessler, F. and Schulz, A. and Schwanke, U. and Schwemmer, S. and Seglar-Arroyo, M. and Settimo, M. and Seyffert, A. S. and Shafi, N. and Shilon, I. and Simoni, R. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stycz, K. and Sushch, I. and Takahashi, T. and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tibaldo, L. and Tiziani, D. and Tluczykont, M. and Trichard, C. and Tsuji, N. and Tuffs, R. and Uchiyama, Y. and van der Walt, D. J. and van Eldik, C. and van Rensburg, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venters, C. and Viana, A. and Vincent, P. and Vink, J. and Voisin, F. and Voelk, H. J. and Vuillaume, T. and Wadiasingh, Z. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zaborov, D. and Zacharias, M. and Zanin, R. and Zdziarski, A. A. and Zech, Alraune and Zefi, F. and Ziegler, A. and Zywucka, N.}, title = {Characterising the VHE diffuse emission in the central 200 parsecs of our Galaxy with HESS}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {612}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, organization = {H E S S Collaboration}, issn = {1432-0746}, doi = {10.1051/0004-6361/201730824}, pages = {13}, year = {2018}, abstract = {The diffuse very high-energy (VHE; > 100 GeV) gamma-ray emission observed in the central 200 pc of the Milky Way by H.E.S.S. was found to follow dense matter distribution in the central molecular zone (CMZ) up to a longitudinal distance of about 130 pc to the Galactic centre (GC), where the flux rapidly decreases. This was initially interpreted as the result of a burst-like injection of energetic particles 104 yr ago, but a recent more sensitive H.E.S.S. analysis revealed that the cosmic-ray (CR) density profile drops with the distance to the centre, making data compatible with a steady cosmic PeVatron at the GC. In this paper, we extend this analysis to obtain, for the first time, a detailed characterisation of the correlation with matter and to search for additional features and individual gamma-ray sources in the inner 200 pc. Taking advantage of 250 h of H.E.S.S. data and improved analysis techniques, we perform a detailed morphology study of the diffuse VHE emission observed from the GC ridge and reconstruct its total spectrum. To test the various contributions to the total gamma-ray emission, we used an iterative 2D maximum-likelihood approach that allows us to build a phenomenological model of the emission by summing a number of different spatial components. We show that the emission correlated with dense matter covers the full CMZ and that its flux is about half the total diffuse emission flux. We also detect some emission at higher latitude that is likely produced by hadronic collisions of CRs in less dense regions of the GC interstellar medium. We detect an additional emission component centred on the GC and extending over about 15 pc that is consistent with the existence of a strong CR density gradient and confirms the presence of a CR accelerator at the very centre of our Galaxy. We show that the spectrum of full ridge diffuse emission is compatible with that previously derived from the central regions, suggesting that a single population of particles fills the entire CMZ. Finally, we report the discovery of a VHE gamma-ray source near the GC radio arc and argue that it is produced by the pulsar wind nebula candidate G0.13-0.11.}, language = {en} } @article{ChanChaudharySahaetal.2021, author = {Chan, Lili and Chaudhary, Kumardeep and Saha, Aparna and Chauhan, Kinsuk and Vaid, Akhil and Zhao, Shan and Paranjpe, Ishan and Somani, Sulaiman and Richter, Felix and Miotto, Riccardo and Lala, Anuradha and Kia, Arash and Timsina, Prem and Li, Li and Freeman, Robert and Chen, Rong and Narula, Jagat and Just, Allan C. and Horowitz, Carol and Fayad, Zahi and Cordon-Cardo, Carlos and Schadt, Eric and Levin, Matthew A. and Reich, David L. and Fuster, Valentin and Murphy, Barbara and He, John C. and Charney, Alexander W. and B{\"o}ttinger, Erwin and Glicksberg, Benjamin and Coca, Steven G. and Nadkarni, Girish N.}, title = {AKI in hospitalized patients with COVID-19}, series = {Journal of the American Society of Nephrology : JASN}, volume = {32}, journal = {Journal of the American Society of Nephrology : JASN}, number = {1}, publisher = {American Society of Nephrology}, address = {Washington}, organization = {Mt Sinai COVID Informatics Ct}, issn = {1046-6673}, doi = {10.1681/ASN.2020050615}, pages = {151 -- 160}, year = {2021}, abstract = {Background: Early reports indicate that AKI is common among patients with coronavirus disease 2019 (COVID-19) and associatedwith worse outcomes. However, AKI among hospitalized patients with COVID19 in the United States is not well described. Methods: This retrospective, observational study involved a review of data from electronic health records of patients aged >= 18 years with laboratory-confirmed COVID-19 admitted to the Mount Sinai Health System from February 27 to May 30, 2020. We describe the frequency of AKI and dialysis requirement, AKI recovery, and adjusted odds ratios (aORs) with mortality. Results: Of 3993 hospitalized patients with COVID-19, AKI occurred in 1835 (46\%) patients; 347 (19\%) of the patientswith AKI required dialysis. The proportionswith stages 1, 2, or 3 AKIwere 39\%, 19\%, and 42\%, respectively. A total of 976 (24\%) patients were admitted to intensive care, and 745 (76\%) experienced AKI. Of the 435 patients with AKI and urine studies, 84\% had proteinuria, 81\% had hematuria, and 60\% had leukocyturia. Independent predictors of severe AKI were CKD, men, and higher serum potassium at admission. In-hospital mortality was 50\% among patients with AKI versus 8\% among those without AKI (aOR, 9.2; 95\% confidence interval, 7.5 to 11.3). Of survivors with AKI who were discharged, 35\% had not recovered to baseline kidney function by the time of discharge. An additional 28 of 77 (36\%) patients who had not recovered kidney function at discharge did so on posthospital follow-up. Conclusions: AKI is common among patients hospitalized with COVID-19 and is associated with high mortality. Of all patients with AKI, only 30\% survived with recovery of kidney function by the time of discharge.}, language = {en} } @article{SigelSwartzGoldenetal.2020, author = {Sigel, Keith Magnus and Swartz, Talia H. and Golden, Eddye and Paranjpe, Ishan and Somani, Sulaiman and Richter, Felix and De Freitas, Jessica K. and Miotto, Riccardo and Zhao, Shan and Polak, Paz and Mutetwa, Tinaye and Factor, Stephanie and Mehandru, Saurabh and Mullen, Michael and Cossarini, Francesca and B{\"o}ttinger, Erwin and Fayad, Zahi and Merad, Miriam and Gnjatic, Sacha and Aberg, Judith and Charney, Alexander and Nadkarni, Girish and Glicksberg, Benjamin S.}, title = {Coronavirus 2019 and people living with human immunodeficiency virus}, series = {Clinical infectious diseases : electronic edition}, volume = {71}, journal = {Clinical infectious diseases : electronic edition}, number = {11}, publisher = {Oxford Univ. Press}, address = {Cary, NC}, issn = {1058-4838}, doi = {10.1093/cid/ciaa880}, pages = {2933 -- 2938}, year = {2020}, abstract = {Background: There are limited data regarding the clinical impact of coronavirus disease 2019 (COVID-19) on people living with human immunodeficiency virus (PLWH). In this study, we compared outcomes for PLWH with COVID-19 to a matched comparison group. Methods: We identified 88 PLWH hospitalized with laboratory-confirmed COVID-19 in our hospital system in New York City between 12 March and 23 April 2020. We collected data on baseline clinical characteristics, laboratory values, HIV status, treatment, and outcomes from this group and matched comparators (1 PLWH to up to 5 patients by age, sex, race/ethnicity, and calendar week of infection). We compared clinical characteristics and outcomes (death, mechanical ventilation, hospital discharge) for these groups, as well as cumulative incidence of death by HIV status. Results: Patients did not differ significantly by HIV status by age, sex, or race/ethnicity due to the matching algorithm. PLWH hospitalized with COVID-19 had high proportions of HIV virologic control on antiretroviral therapy. PLWH had greater proportions of smoking (P < .001) and comorbid illness than uninfected comparators. There was no difference in COVID-19 severity on admission by HIV status (P = .15). Poor outcomes for hospitalized PLWH were frequent but similar to proportions in comparators; 18\% required mechanical ventilation and 21\% died during follow-up (compared with 23\% and 20\%, respectively). There was similar cumulative incidence of death over time by HIV status (P = .94). Conclusions: We found no differences in adverse outcomes associated with HIV infection for hospitalized COVID-19 patients compared with a demographically similar patient group.}, language = {en} } @article{VaidSomaniRussaketal.2020, author = {Vaid, Akhil and Somani, Sulaiman and Russak, Adam J. and De Freitas, Jessica K. and Chaudhry, Fayzan F. and Paranjpe, Ishan and Johnson, Kipp W. and Lee, Samuel J. and Miotto, Riccardo and Richter, Felix and Zhao, Shan and Beckmann, Noam D. and Naik, Nidhi and Kia, Arash and Timsina, Prem and Lala, Anuradha and Paranjpe, Manish and Golden, Eddye and Danieletto, Matteo and Singh, Manbir and Meyer, Dara and O'Reilly, Paul F. and Huckins, Laura and Kovatch, Patricia and Finkelstein, Joseph and Freeman, Robert M. and Argulian, Edgar and Kasarskis, Andrew and Percha, Bethany and Aberg, Judith A. and Bagiella, Emilia and Horowitz, Carol R. and Murphy, Barbara and Nestler, Eric J. and Schadt, Eric E. and Cho, Judy H. and Cordon-Cardo, Carlos and Fuster, Valentin and Charney, Dennis S. and Reich, David L. and B{\"o}ttinger, Erwin and Levin, Matthew A. and Narula, Jagat and Fayad, Zahi A. and Just, Allan C. and Charney, Alexander W. and Nadkarni, Girish N. and Glicksberg, Benjamin S.}, title = {Machine learning to predict mortality and critical events in a cohort of patients with COVID-19 in New York City: model development and validation}, series = {Journal of medical internet research : international scientific journal for medical research, information and communication on the internet ; JMIR}, volume = {22}, journal = {Journal of medical internet research : international scientific journal for medical research, information and communication on the internet ; JMIR}, number = {11}, publisher = {Healthcare World}, address = {Richmond, Va.}, issn = {1439-4456}, doi = {10.2196/24018}, pages = {19}, year = {2020}, abstract = {Background: COVID-19 has infected millions of people worldwide and is responsible for several hundred thousand fatalities. The COVID-19 pandemic has necessitated thoughtful resource allocation and early identification of high-risk patients. However, effective methods to meet these needs are lacking. Objective: The aims of this study were to analyze the electronic health records (EHRs) of patients who tested positive for COVID-19 and were admitted to hospitals in the Mount Sinai Health System in New York City; to develop machine learning models for making predictions about the hospital course of the patients over clinically meaningful time horizons based on patient characteristics at admission; and to assess the performance of these models at multiple hospitals and time points. Methods: We used Extreme Gradient Boosting (XGBoost) and baseline comparator models to predict in-hospital mortality and critical events at time windows of 3, 5, 7, and 10 days from admission. Our study population included harmonized EHR data from five hospitals in New York City for 4098 COVID-19-positive patients admitted from March 15 to May 22, 2020. The models were first trained on patients from a single hospital (n=1514) before or on May 1, externally validated on patients from four other hospitals (n=2201) before or on May 1, and prospectively validated on all patients after May 1 (n=383). Finally, we established model interpretability to identify and rank variables that drive model predictions. Results: Upon cross-validation, the XGBoost classifier outperformed baseline models, with an area under the receiver operating characteristic curve (AUC-ROC) for mortality of 0.89 at 3 days, 0.85 at 5 and 7 days, and 0.84 at 10 days. XGBoost also performed well for critical event prediction, with an AUC-ROC of 0.80 at 3 days, 0.79 at 5 days, 0.80 at 7 days, and 0.81 at 10 days. In external validation, XGBoost achieved an AUC-ROC of 0.88 at 3 days, 0.86 at 5 days, 0.86 at 7 days, and 0.84 at 10 days for mortality prediction. Similarly, the unimputed XGBoost model achieved an AUC-ROC of 0.78 at 3 days, 0.79 at 5 days, 0.80 at 7 days, and 0.81 at 10 days. Trends in performance on prospective validation sets were similar. At 7 days, acute kidney injury on admission, elevated LDH, tachypnea, and hyperglycemia were the strongest drivers of critical event prediction, while higher age, anion gap, and C-reactive protein were the strongest drivers of mortality prediction. Conclusions: We externally and prospectively trained and validated machine learning models for mortality and critical events for patients with COVID-19 at different time horizons. These models identified at-risk patients and uncovered underlying relationships that predicted outcomes.}, language = {en} } @article{AbdallaAbramowskiAharonianetal.2018, author = {Abdalla, Hassan E. and Abramowski, A. and Aharonian, Felix A. and Benkhali, F. Ait and Akhperjanian, A. G. and Andersson, T. and Anguener, E. O. and Arakawa, M. and Arrieta, M. and Aubert, P. and Backes, M. and Balzer, A. and Barnard, M. and Becherini, Y. and Tjus, J. Becker and Berge, D. and Bernhard, S. and Bernloehr, K. and Blackwell, R. and Boettcher, M. and Boisson, C. and Bolmont, J. and Bordas, Pol and Bregeon, J. and Brun, F. and Brun, P. and Bryan, M. and Bilchele, M. and Bulik, T. and Capasso, M. and Carr, J. and Casanova, Sabrina and Cerruti, M. and Chakraborty, N. and Chalme-Calvet, R. and Chaves, R. C. G. and Chen, A. and Chevalier, J. and Chretien, M. and Coffaro, M. and Colafrancesco, S. and Cologna, G. and Condon, B. and Conrad, J. and Cui, Y. and Davids, I. D. and Decock, J. and Degrange, B. and Deil, C. and Devin, J. and deWilt, P. and Dirson, L. and Djannati-Atai, A. and Domainko, W. and Donath, A. and Dutson, K. and Dyks, J. and Edwards, T. and Egberts, Kathrin and Eger, P. and Ernenwein, J. -P. and Eschbach, S. and Farnier, C. and Fegan, S. and Fernandes, M. V. and Fiasson, A. and Fontaine, G. and Foerster, A. and Funk, S. and Fuessling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Goya, A. and Grondin, M. -H. and Hahn, J. and Haupt, M. and Hawkes, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hinton, J. A. and Hofmann, W. and Hoischen, Clemens and Holler, M. and Horns, D. and Ivascenko, A. and Iwasaki, H. and Jacholkowska, A. and Jamrozy, M. and Janiak, M. and Jankowsky, D. and Jankowsky, F. and Jingo, M. and Jogler, T. and Jouvin, L. and Jung-Richardt, I. and Kastendieck, M. A. and Katarzynski, K. and Katsuragawa, M. and Katz, U. and Kerszberg, D. and Khangulyan, D. and Khelifi, B. and Kieffer, M. and King, J. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Kraus, M. and Krueger, P. P. and Laffon, H. and Lamanna, G. and Lau, J. and Lees, J. -P. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Leser, Eva and Lohse, T. and Lorentz, M. and Liu, R. and Lopez-Coto, R. and Lypova, I. and Marandon, V. and Marcowith, Alexandre and Mariaud, C. and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and Meintjes, P. J. and Meyer, M. and Mitche, A. M. W. and Moderski, R. and Mohamed, M. and Mohrmann, L. and Mora, K. and Moulin, Emmanuel and Murach, T. and Nakashima, S. and de Naurois, M. and Niederwanger, F. and Niemiec, J. and Oakes, L. and Odaka, H. and Oettl, S. and Ohm, S. and Ostrowski, M. and Oya, I. and Padovani, M. and Panter, M. and Parsons, R. D. and Arribas, M. Paz and Pekeur, N. W. and Pelletier, G. and Perennes, C. and Petrucci, P. -O. and Peyaud, B. and Piel, Q. and Pita, S. and Poon, H. and Prokhorov, D. and Prokoph, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reimer, A. and Reimer, O. and Renaud, M. and de los Reyes, R. and Richter, S. and Rieger, F. and Romoli, C. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Saito, S. and Salek, D. and Sanchez, D. A. and Santangelo, Andrea and Sasaki, M. and Schlickeiser, R. and Schuessler, F. and Schulz, A. and Schwanke, U. and Schwemmer, S. and Seglar-Arroyo, M. and Settimo, M. and Seyffert, A. S. and Shafi, N. and Shilon, I. and Simoni, R. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stycz, K. and Sushch, I. and Takahashi, T. and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tibaldo, L. and Tiziani, D. and Tluczykont, M. and Trichard, C. and Tsuji, N. and Tuffs, R. and Uchiyama, Y. and van der Walt, D. J. and van Eldik, C. and van Rensburg, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voisin, F. and Voelk, H. J. and Vuillaume, T. and Wadiasingh, Z. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zanin, R. and Zdziarski, A. A. and Zech, Alraune and Zefi, F. and Ziegler, A. and Zywucka, N.}, title = {Deeper HESS observations of Vela Junior (RX J0852.0-4622)}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {612}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, organization = {H E S S Collaboration}, issn = {1432-0746}, doi = {10.1051/0004-6361/201630002}, pages = {14}, year = {2018}, abstract = {Aims. We study gamma-ray emission from the shell-type supernova remnant (SNR) RXJ0852.0-4622 to better characterize its spectral properties and its distribution over the SNR. Methods. The analysis of an extended High Energy Spectroscopic System (H.E.S.S.) data set at very high energies (E > 100 GeV) permits detailed studies, as well as spatially resolved spectroscopy, of the morphology and spectrum of the whole RXJ0852.0-4622 region. The H.E.S.S. data are combined with archival data from other wavebands and interpreted in the framework of leptonic and hadronic models. The joint Fermi-LAT-H.E.S.S. spectrum allows the direct determination of the spectral characteristics of the parent particle population in leptonic and hadronic scenarios using only GeV-TeV data. Results. An updated analysis of the H.E.S.S. data shows that the spectrum of the entire SNR connects smoothly to the high-energy spectrum measured by Fermi-LAT. The increased data set makes it possible to demonstrate that the H.E.S.S. spectrum deviates significantly from a power law and is well described by both a curved power law and a power law with an exponential cutoff at an energy of E-cut = (6.7 +/- 1.2(stat) +/- 1.2(syst)) TeV. The joint Fermi-LAT-H.E.S.S. spectrum allows the unambiguous identification of the spectral shape as a power law with an exponential cutoff. No significant evidence is found for a variation of the spectral parameters across the SNR, suggesting similar conditions of particle acceleration across the remnant. A simple modeling using one particle population to model the SNR emission demonstrates that both leptonic and hadronic emission scenarios remain plausible. It is also shown that at least a part of the shell emission is likely due to the presence of a pulsar wind nebula around PSR J0855-4644.}, language = {en} } @article{AbdallaAbramowskiAharonianetal.2018, author = {Abdalla, Hassan E. and Abramowski, A. and Aharonian, Felix A. and Benkhali, F. Ait and Akhperjanian, A. G. and Andersson, T. and Anguener, E. O. and Arakawa, M. and Arrieta, M. and Aubert, P. and Backes, M. and Balzer, A. and Barnard, M. and Becherini, Y. and Tjus, J. Becker and Berge, D. and Bernhard, S. and Bernloehr, K. and Blackwell, R. and Bottcher, M. and Boisson, C. and Bolmont, J. and Bordas, Pol and Bregeon, J. and Brun, F. and Brun, P. and Bryan, M. and Buechele, M. and Bulik, T. and Capasso, M. and Carr, J. and Casanova, Sabrina and Cerruti, M. and Chakraborty, N. and Chalme-Calvet, R. and Chaves, R. C. G. and Chen, A. and Chevalier, J. and Chretien, M. and Coffaro, M. and Colafrancesco, S. and Cologna, G. and Condon, B. and Conrad, J. and Cui, Y. and Davids, I. D. and Decock, J. and Degrange, B. and Deil, C. and Devin, J. and deWilt, P. and Dirson, L. and Djannati-Atai, A. and Domainko, W. and Donath, A. and Dutson, K. and Dyks, J. and Edwards, T. and Egberts, Kathrin and Eger, P. and Ernenwein, J. -P. and Eschbach, S. and Farnier, C. and Fegan, S. and Fernandes, M. V. and Fiasson, A. and Fontaine, G. and Foerster, A. and Funk, S. and Fuessling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Goyal, A. and Grondin, M. -H. and Hahn, J. and Haupt, M. and Hawkes, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hinton, J. A. and Hofmann, W. and Hoischen, Clemens and Holler, M. and Horns, D. and Ivascenko, A. and Iwasaki, H. and Jacholkowska, A. and Jamrozy, M. and Janiak, M. and Jankowsky, D. and Jankowsky, F. and Jingo, M. and Jogler, T. and Jouvin, L. and Jung-Richardt, I. and Kastendieck, M. A. and Katarzynski, K. and Katsuragawa, M. and Katz, U. and Kerszberg, D. and Khangulyan, D. and Khelifi, B. and Kieffer, M. and King, J. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Kraus, M. and Kruger, P. P. and Laffon, H. and Lamanna, G. and Lau, J. and Lees, J. -P. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Leser, Eva and Lohse, T. and Lorentz, M. and Liu, R. and Lopez-Coto, R. and Lypova, I. and Marandon, V. and Marcowith, Alexandre and Mariaud, C. and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and Meintjes, P. J. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mohrmann, L. and Mora, K. and Moulin, Emmanuel and Murach, T. and Nakashima, S. and de Naurois, M. and Niederwanger, F. and Niemiec, J. and Oakes, L. and Odaka, H. and Oettl, S. and Ohm, S. and Ostrowski, M. and Oya, I. and Padovani, M. and Panter, M. and Parsons, R. D. and Pekeur, N. W. and Pelletier, G. and Perennes, C. and Petrucci, P. -O. and Peyaud, B. and Piel, Q. and Pita, S. and Poon, H. and Prokhorov, D. and Prokoph, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reimer, A. and Reimer, O. and Renaud, M. and de los Reyes, R. and Richter, S. and Rieger, F. and Romoli, C. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Saito, S. and Salek, D. and Sanchez, D. A. and Santangelo, Andrea and Sasaki, M. and Schlickeiser, R. and Schussler, F. and Schulz, A. and Schwanke, U. and Schwemmer, S. and Seglar-Arroyo, M. and Settimo, M. and Seyffert, A. S. and Shafi, N. and Shilon, I. and Simoni, R. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian Michael and Stycz, K. and Sushch, I. and Takahashi, T. and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tibaldo, L. and Tiziani, D. and Tluczykont, M. and Trichard, C. and Tsuji, N. and Tuffs, R. and Uchiyama, Y. and van der Walt, D. J. and van Eldik, C. and van Rensburg, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voisin, F. and Voelk, H. J. and Vuillaume, T. and Wadiasingh, Z. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zanin, R. and Zdziarski, A. A. and Zech, Alraune and Zefi, F. and Ziegler, A. and Zywucka, N.}, title = {Systematic search for very-high-energy gamma-ray emission from bow shocks of runaway stars}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {612}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, organization = {HESS Collaboration}, issn = {1432-0746}, doi = {10.1051/0004-6361/201630151}, pages = {6}, year = {2018}, abstract = {Context. Runaway stars form bow shocks by ploughing through the interstellar medium at supersonic speeds and are promising sources of non-thermal emission of photons. One of these objects has been found to emit non-thermal radiation in the radio band. This triggered the development of theoretical models predicting non-thermal photons from radio up to very-high-energy (VHE, E >= 0.1 TeV) gamma rays. Subsequently, one bow shock was also detected in X-ray observations. However, the data did not allow discrimination between a hot thermal and a non-thermal origin. Further observations of different candidates at X-ray energies showed no evidence for emission at the position of the bow shocks either. A systematic search in the Fermi-LAT energy regime resulted in flux upper limits for 27 candidates listed in the E-BOSS catalogue. Aims. Here we perform the first systematic search for VHE gamma-ray emission from bow shocks of runaway stars. Methods. Using all available archival H.E.S.S. data we search for very-high-energy gamma-ray emission at the positions of bow shock candidates listed in the second E-BOSS catalogue release. Out of the 73 bow shock candidates in this catalogue, 32 have been observed with H.E.S.S. Results. None of the observed 32 bow shock candidates in this population study show significant emission in the H.E.S.S. energy range. Therefore, flux upper limits are calculated in five energy bins and the fraction of the kinetic wind power that is converted into VHE gamma rays is constrained. Conclusions. Emission from stellar bow shocks is not detected in the energy range between 0.14 and 18 TeV. The resulting upper limits constrain the level of VHE gamma-ray emission from these objects down to 0.1-1\% of the kinetic wind energy.}, language = {en} } @article{AbdallaAbramowskiAharonianetal.2018, author = {Abdalla, Hassan E. and Abramowski, A. and Aharonian, Felix A. and Benkhali, F. Ait and Akhperjanian, A. G. and Andersson, T. and Anguener, E. O. and Arakawa, M. and Arrieta, M. and Aubert, P. and Backes, M. and Balzer, A. and Barnard, M. and Becherini, Y. and Tjus, J. Becker and Berge, D. and Bernhard, S. and Bernloehr, K. and Blackwell, R. and Boettcher, M. and Boisson, C. and Bolmont, J. and Bonnefoy, S. and Bordas, Pol and Bregeon, J. and Brun, F. and Brun, P. and Bryan, M. and Buechele, M. and Bulik, T. and Capasso, M. and Carr, J. and Casanova, Sabrina and Cerruti, M. and Chakraborty, N. and Chaves, R. C. G. and Chen, A. and Chevalier, J. and Coffaro, M. and Colafrancesco, S. and Cologna, G. and Condon, B. and Conrad, J. and Cui, Y. and Davids, I. D. and Decock, J. and Degrange, B. and Deil, C. and Devin, J. and deWilt, P. and Dirson, L. and Djannati-Atai, A. and Domainko, W. and Donath, A. and Dutson, K. and Dyks, J. and Edwards, T. and Egberts, Kathrin and Eger, P. and Ernenwein, J. -P. and Eschbach, S. and Farnier, C. and Fegan, S. and Fernandes, M. V. and Fiasson, A. and Fontaine, G. and Foerster, A. and Funk, S. and Fuessling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Goyal, A. and Grondin, M. -H. and Hahn, J. and Haupt, M. and Hawkes, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hinton, J. A. and Hofmann, W. and Hoischen, Clemens and Holch, T. L. and Holler, M. and Horns, D. and Ivascenko, A. and Iwasaki, H. and Jacholkowska, A. and Jamrozy, M. and Janiak, M. and Jankowsky, D. and Jankowsky, F. and Jingo, M. and Jogler, T. and Jouvin, L. and Jung-Richardt, I. and Kastendieck, M. A. and Katarzynski, K. and Katsuragawa, M. and Katz, U. and Kerszberg, D. and Khangulyan, D. and Khelifi, B. and King, J. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Kraus, M. and Krueger, P. P. and Laffon, H. and Lamanna, G. and Lau, J. and Lees, J. -P. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Leser, Eva and Lohse, T. and Lorentz, M. and Liu, R. and Lopez-Coto, R. and Lypova, I. and Marandon, V. and Marcowith, Alexandre and Mariaud, C. and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and Meintjes, P. J. and Meyer, M. and Mitche, A. M. W. and Moderski, R. and Mohamed, M. and Mohrmann, L. and Mora, K. and Moulin, Emmanuel and Murach, T. and Nakashima, S. and de Naurois, M. and Niederwanger, F. and Niemiec, J. and Oakes, L. and Odaka, H. and Oettl, S. and Ohm, S. and Ostrowski, M. and Oya, I. and Padovani, M. and Panter, M. and Parsons, R. D. and Pekeur, N. W. and Pelletier, G. and Perennes, C. and Petrucci, P. -O. and Peyaud, B. and Piel, Q. and Pita, S. and Poon, H. and Prokhorov, D. and Prokoph, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reimer, A. and Reimer, O. and Renaud, M. and de los Reyes, R. and Richter, S. and Rieger, F. and Romoli, C. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Saito, S. and Salek, D. and Sanchez, D. A. and Santangelo, Andrea and Sasaki, M. and Schlickeiser, R. and Schuessler, F. and Schulz, A. and Schwanke, U. and Schwemmer, S. and Seglar-Arroyo, M. and Settimo, M. and Seyffert, A. S. and Shafi, N. and Shilon, I. and Simoni, R. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stycz, K. and Sushch, I. and Takahashi, T. and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tibaldo, L. and Tiziani, D. and Tluczykont, M. and Trichard, C. and Tsuji, N. and Tuffs, R. and Uchiyama, Y. and van der Wale, D. J. and van Eldik, C. and van Rensburg, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voisin, F. and Voelk, H. J. and Vuillaume, T. and Wadiasingh, Z. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zanin, R. and Zdziarski, A. A. and Zech, Alraune and Zefi, F. and Ziegler, A. and Zywucka, N. and Bamba, A. and Fukui, Y. and Sano, H. and Yoshiike, S.}, title = {A search for new supernova remnant shells in the Galactic plane with HESS}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {612}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, organization = {H E S S Collaboration}, issn = {1432-0746}, doi = {10.1051/0004-6361/201730737}, pages = {23}, year = {2018}, abstract = {A search for new supernova remnants (SNRs) has been conducted using TeV gamma-ray data from the H.E.S.S. Galactic plane survey. As an identification criterion, shell morphologies that are characteristic for known resolved TeV SNRs have been used. Three new SNR candidates were identified in the H.E.S.S. data set with this method. Extensive multiwavelength searches for counterparts were conducted. A radio SNR candidate has been identified to be a counterpart to HESS J1534-571. The TeV source is therefore classified as a SNR. For the other two sources, HESS J1614-518 and HESS J1912 + 101, no identifying counterparts have been found, thus they remain SNR candidates for the time being. TeV-emitting SNRs are key objects in the context of identifying the accelerators of Galactic cosmic rays. The TeV emission of the relativistic particles in the new sources is examined in view of possible leptonic and hadronic emission scenarios, taking the current multiwavelength knowledge into account.}, language = {en} } @article{AhnenAnsoldiAntonellietal.2018, author = {Ahnen, M. L. and Ansoldi, S. and Antonelli, L. A. and Arcaro, C. and Babie, A. and Banerjee, B. and Bangale, P. and de Almeida, U. Barres and Barrio, J. A. and Gonzalez, J. Becerra and Bednarek, W. and Bernardini, E. and Berti, A. and Biasuzzi, B. and Biland, A. and Blanch, O. and Bonnefoy, S. and Bonnoli, G. and Borracci, F. and Carosi, R. and Carosi, A. and Chatterjee, A. and Colin, P. and Colombo, E. and Contreras, J. L. and Cortina, J. and Covino, S. and Cumani, P. and Da Vela, P. and Dazzi, F. and De Angelis, A. and De Lotto, B. and Wilhelmi, E. de Ona and Di Pierro, F. and Doert, M. and Dominguez, A. and Prester, D. Dominis and Dorner, D. and Doro, M. and Einecke, S. and Glawion, D. Eisenacher and Elsaesser, D. and Engelkemeier, M. and Ramazani, V. Fallah and Fernandez-Barra, A. and Fidalgo, D. and Fonseca, M. V. and Font, L. and Fruck, C. and Galindo, D. and Lopez, R. J. Garcia and Garczarczyk, M. and Gaug, M. and Giammaria, P. and Godinovie, N. and Gora, D. and Griffiths, S. and Guberman, D. and Hadasch, D. and Hahn, A. and Hassan, T. and Hayashida, M. and Herrera, J. and Hose, J. and Hrupec, D. and Hughes, G. and Ishio, K. and Konno, Y. and Kubo, H. and Kushida, J. and Kuvezdie, D. and Lelas, D. and Lindfors, E. and Lombardi, S. and Longo, F. and Lopez, M. and Lopez-Oramas, A. and Majumdar, P. and Makariev, M. and Maneva, G. and Manganaro, M. and Mannheim, K. and Maraschi, L. and Mariotti, M. and Martinez, M. and Mazin, D. and Menzel, U. and Minev, M. and Mirzoyan, R. and Moralejo, A. and Moreno, V. and Moretti, E. and Munar-Adrover, P. and Neustroev, V. and Niedzwiecki, A. and Rosillo, M. Nievas and Nilsson, K. and Nishijima, K. and Noda, K. and Nogues, L. and Paiano, S. and Palacio, J. and Paneque, D. and Paoletti, R. and Paredes, J. M. and Paredes-Fortuny, X. and Pedaletti, G. and Peresano, M. and Perri, L. and Persic, M. and Moroni, P. G. Prada and Prandini, E. and Puljak, I. and Garcia, J. R. and Reichardt, I. and Rhode, W. and Riti, M. and Rico, J. and Saito, T. and Satalecka, K. and Schroeder, S. and Schweizer, T. and Shore, S. N. and Sillanpaa, A. and Sitarek, J. and Sobczynskall, D. and Stamerra, A. and Strzys, M. and Surie, T. and Takalo, L. and Tavecchio, F. and Temnikov, P. and Terzie, T. and Tescaro, D. and Teshima, M. and Torres, D. F. and Torres-Alla, N. and Treves, A. and Vanzo, G. and Acosta, M. Vazquez and Vovk, I. and Ward, J. E. and Will, M. and Wu, M. H. and Zarie, D. and Abdalla, Hassan E. and Abramowski, A. and Aharonian, Felix A. and Benkhali, F. Ait and Akhperjanian, A. G. and Andersson, T. and Ang{\"u}ner, Ekrem Oǧuzhan and Arakawa, M. and Arrieta, M. and Aubert, P. and Backes, M. and Balzer, A. and Barnard, M. and Becherini, Y. and Tjus, J. Becker and Berge, D. and Bernhard, S. and Bernlohr, K. and Blackwell, R. and Bottcher, M. and Boisson, C. and Bolmont, J. and Bordas, Pol and Bregeon, J. and Brun, F. and Brun, P. and Bryan, M. and Btichele, M. and Bulik, T. and Capasso, M. and Carr, J. and Casanova, Sabrina and Cerruti, M. and Chakraborty, N. and Chalme-Calvet, R. and Chaves, R. C. G. and Chen, A. and Chevalier, J. and Chretien, M. and Coffaro, M. and Colafrancesco, S. and Cologna, G. and Condon, B. and Conrad, J. and Cui, Y. and Davids, I. D. and Decock, J. and Degrange, B. and Dei, C. and Devin, J. and Dewilt, P. and Dirson, L. and Djannati-Atai, A. and Domainko, W. and Donath, A. and Dutson, K. and Dyks, J. and Edwards, T. and Egberts, Kathrin and Eger, P. and Ernenwein, J. -P. and Eschbach, S. and Farnier, C. and Fegan, S. and Fernandes, M. V. and Fiasson, A. and Fontaine, G. and Forster, A. and Funk, S. and Ftifiling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschal, D. and Goya, A. and Grondin, M. -H. and Hahn, J. and Haupt, M. and Hawkes, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hinton, J. A. and Hofmann, W. and Hoischen, Clemens and Holler, M. and Horns, D. and Ivascenko, A. and Iwasaki, H. and Jacholkowska, A. and Jamrozy, M. and Janiak, M. and Jankowsky, D. and Jankowsky, F. and Jingo, M. and Jogler, T. and Jouvin, L. and Jung-Richardt, I. and Kastendieck, M. A. and Katarzyfiski, K. and Katsuragawa, M. and Katz, U. and Kerszberg, D. and Khangulyan, D. and Khelifi, B. and Kieffer, M. and King, J. and Klepser, S. and Klochkov, D. and Kluiniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Kraus, M. and Krtiger, P. P. and Laffon, H. and Lamanna, G. and Lau, J. and Lees, J. -P. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Leser, Eva and Lohse, T. and Lorentz, M. and Liu, R. and Lopez-Coto, R. and Lypova, I. and Marandon, V. and Marcowith, Alexandre and Mariaud, C. and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and Meintjes, P. J. and Meyer, M. and Mitche, A. M. W. and Moderski, R. and Mohamed, M. and Mohrmann, L. and Mora, K. and Moulin, Emmanuel and Murach, T. and Nakashima, S. and De Naurois, M. and Niederwanger, F. and Niemiec, J. and Oakes, L. and Odaka, H. and Ott, S. and Ohm, S. and Ostrowski, M. and Oya, I. and Padovani, M. and Panter, M. and Parsons, R. D. and Pekeur, N. W. and Pelletier, G. and Perennes, C. and Petrucci, P. -O. and Peyaud, B. and Pie, Q. and Pita, S. and Poon, H. and Prokhorov, D. and Prokoph, H. and Ptffilhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reimer, A. and Reimer, O. and Renaud, M. and De Los Reyes, R. and Richter, S. and Rieger, F. and Romoli, C. and Rowell, G. and Rudak, B. and Rulten, C. B. and Safi-Harb, S. and Sahakian, V. and Saito, S. and Salek, D. and Sanchez, D. A. and Santangelo, Andrea and Sasaki, M. and Schlickeiser, R. and Schtissler, F. and Schulz, A. and Schwanke, U. and Schwemmer, S. and Seglar-Arroyo, M. and Settimo, M. and Seyffert, A. S. and Shafi, N. and Shilon, I. and Simoni, R. and So, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stycz, K. and Sushch, I. and Takahashi, T. and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tibaldo, L. and Tiziani, D. and Tluczykont, M. and Trichard, C. and Tsuji, N. and Tuffs, R. and Uchiyama, Y. and Van der Walt, D. J. and Van Eldik, C. and Van Rensburg, C. and Van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voisin, F. and Vok, H. J. and Vuillaume, T. and Wadiasingh, Z. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and White, R. and Wierzcholska, A. and Willmann, P. and Wornlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zanin, R. and Zdziarski, A. A. and Zech, Alraune and Zefi, F. and Ziegler, A. and Zywuckan, N.}, title = {Constraints on particle acceleration in SS433/W50 from MAGIC and HESS observations}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {612}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, organization = {HESS Collaboratio MAGIC Collaboration}, issn = {1432-0746}, doi = {10.1051/0004-6361/201731169}, pages = {8}, year = {2018}, abstract = {Context. The large jet kinetic power and non-thermal processes occurring in the microquasar SS 433 make this source a good candidate for a very high-energy (VHE) gamma-ray emitter. Gamma-ray fluxes above the sensitivity limits of current Cherenkov telescopes have been predicted for both the central X-ray binary system and the interaction regions of SS 433 jets with the surrounding W50 nebula. Non-thermal emission at lower energies has been previously reported, indicating that efficient particle acceleration is taking place in the system. Aims. We explore the capability of SS 433 to emit VHE gamma rays during periods in which the expected flux attenuation due to periodic eclipses (P-orb similar to 13.1 days) and precession of the circumstellar disk (P-pre similar to 162 days) periodically covering the central binary system is expected to be at its minimum. The eastern and western SS 433/W50 interaction regions are also examined using the whole data set available. We aim to constrain some theoretical models previously developed for this system with our observations. Methods. We made use of dedicated observations from the Major Atmospheric Gamma Imaging Cherenkov telescopes (MAGIC) and High Energy Spectroscopic System (H.E.S.S.) of SS 433 taken from 2006 to 2011. These observation were combined for the first time and accounted for a total effective observation time of 16.5 h, which were scheduled considering the expected phases of minimum absorption of the putative VHE emission. Gamma-ray attenuation does not affect the jet/medium interaction regions. In this case, the analysis of a larger data set amounting to similar to 40-80 h, depending on the region, was employed. Results. No evidence of VHE gamma-ray emission either from the central binary system or from the eastern/western interaction regions was found. Upper limits were computed for the combined data set. Differential fluxes from the central system are found to be less than or similar to 10(-12)-10(-13) TeV-1 cm(-2) s(-1) in an energy interval ranging from similar to few x 100 GeV to similar to few TeV. Integral flux limits down to similar to 10(-12)-10(-13) ph cm(-2) s(-1) and similar to 10(-13)-10(-14) ph cm(-2) s(-1) are obtained at 300 and 800 GeV, respectively. Our results are used to place constraints on the particle acceleration fraction at the inner jet regions and on the physics of the jet/medium interactions. Conclusions. Our findings suggest that the fraction of the jet kinetic power that is transferred to relativistic protons must be relatively small in SS 433, q(p) <= 2.5 x 10(-5), to explain the lack of TeV and neutrino emission from the central system. At the SS 433/W50 interface, the presence of magnetic fields greater than or similar to 10 mu G is derived assuming a synchrotron origin for the observed X-ray emission. This also implies the presence of high-energy electrons with E-e up to 50 TeV, preventing an efficient production of gamma-ray fluxes in these interaction regions.}, language = {en} }