@inproceedings{HeinischRomeikeKnobelsdorfetal.2013, author = {Heinisch, Isabelle and Romeike, Ralf and Knobelsdorf, Maria and Kreitz, Christoph and Nyl{\´e}n, Aletta and D{\"o}rge, Christina and G{\"o}ttel, Timo and Holz, Jan and Bergner, Nadine and Schroeder, Ulrik and Metzger, Christiane and Haag, Johann and Abke, J{\"o}rg and Schwirtlich, Vincent and Sedelmaier, Yvonne and M{\"u}ller, Dorothee and Frommer, Andreas and Humbert, Ludger and Berges, Marc and M{\"u}hling, Andreas and Hubwieser, Peter and Steuer, Horst and Engbring, Dieter and Selke, Harald and Drews, Paul and Schirmer, Ingrid and Morisse, Marcel and Sagawe, Arno and Rolf, Arno and Friedemann, Stefan and Gr{\"o}ger, Stefan and Schumann, Matthias and Klinger, Melanie and Polutina, Olena and Bibel, Ariane and G{\"o}tz, Christian and Brinda, Torsten and Apel, Rebecca and Berg, Tobias and Bergner, Nadine and Chatti, Mohamed Amine and Leicht-Scholten, Carmen and Schroeder, Ulrik and Al-Saffar, Loay Talib and Petre, Marian and Schirmer, Ingrid and Rick, Detlef}, title = {HDI 2012 - Informatik f{\"u}r eine nachhaltige Zukunft : 5. Fachtagung Hochschuldidaktik der Informatik ; 06.-07. November 2012, Universit{\"a}t Hamburg}, editor = {Forbrig, Peter and Rick, Detlef and Schmolitzky, Axel}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-220-9}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-62891}, pages = {169}, year = {2013}, abstract = {Die Tagungsreihe zur Hochschuldidaktik der Informatik HDI wird vom Fachbereich Informatik und Ausbildung / Didaktik der Informatik (IAD) in der Gesellschaft f{\"u}r Informatik e. V. (GI) organisiert. Sie dient den Lehrenden der Informatik in Studieng{\"a}ngen an Hochschulen als Forum der Information und des Austauschs {\"u}ber neue didaktische Ans{\"a}tze und bildungspolitische Themen im Bereich der Hochschulausbildung aus der fachlichen Perspektive der Informatik. Diese f{\"u}nfte HDI 2012 wurde an der Universit{\"a}t Hamburg organisiert. F{\"u}r sie wurde das spezielle Motto „Informatik f{\"u}r eine nachhaltige Zukunft" gew{\"a}hlt, um insbesondere Fragen der Bildungsrelevanz informatischer Inhalte, der Kompetenzen f{\"u}r Studierende informatisch gepr{\"a}gter Studieng{\"a}nge und der Rolle der Informatik in der Hochschulentwicklung zu diskutieren.}, language = {de} } @inproceedings{FroitzheimBergnerSchroederetal.2015, author = {Froitzheim, Manuel and Bergner, Nadine and Schroeder, Ulrik and Hurtienne, Dominik and Spannagel, Christian and Roderus, Simon and Wienkop, Uwe and Leonhardt, Thiemo and Kwiecien, Alexandra and Schmetz, Arno and Bellgardt, Martin and Naumann, Uwe and Weßels, Doris and Metzger, Christiane and L{\"a}ngrich, Matthias and Schulze, J{\"o}rg and Jakoblew, Marcel and Keil, Reinhard and Winkelnkemper, Felix and Engbring, Dieter and Klar, Tilman-Mathies and Kujath, Bertold and Sch{\"u}tze, Christopher and Fietkau, Julian and Kindsm{\"u}ller, Martin Christof and G{\"o}ttel, Timo and Bergner, Nadine and Taraschewski, Christian and Vosseberg, Karin and Czernik, Sofie and Erb, Ulrike and Vielhaber, Michael and Schlierkamp, Kathrin and Thurner, Veronika and Br{\"o}ker, Kathrin}, title = {HDI 2014 - Gestalten von {\"U}berg{\"a}ngen}, editor = {Forbrig, Peter and Magenheim, Johannes}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-313-8}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-74920}, pages = {186}, year = {2015}, abstract = {Die Tagung HDI 2014 in Freiburg zur Hochschuldidaktik der Informatik HDI wurde erneut vom Fachbereich Informatik und Ausbildung / Didaktik der Informatik (IAD) in der Gesellschaft f{\"u}r Informatik e. V. (GI) organisiert. Sie dient den Lehrenden der Informatik in Studieng{\"a}ngen an Hochschulen als Forum der Information und des Austauschs {\"u}ber neue didaktische Ans{\"a}tze und bildungspolitische Themen im Bereich der Hochschulausbildung aus der fachlichen Perspektive der Informatik. Die HDI 2014 ist nun bereits die sechste Ausgabe der HDI. F{\"u}r sie wurde das spezielle Motto „Gestalten und Meistern von {\"U}berg{\"a}ngen" gew{\"a}hlt. Damit soll ein besonderes Augenmerk auf die {\"U}berg{\"a}nge von Schule zum Studium, vom Bachelor zum Master, vom Studium zur Promotion oder vom Studium zur Arbeitswelt gelegt werden.}, language = {de} } @article{SchmidtSchierackGerberetal.2020, author = {Schmidt, Carsten and Schierack, Peter and Gerber, Ulrike and Schroeder, Christian and Choi, Youngeun and Bald, Ilko and Lehmann, Werner and R{\"o}diger, Stefan}, title = {Streptavidin homologues for applications on solid surfaces at high temperatures}, series = {Langmuir}, volume = {36}, journal = {Langmuir}, number = {2}, publisher = {American Chemical Society}, address = {Washington}, issn = {0743-7463}, doi = {10.1021/acs.langmuir.9b02339}, pages = {628 -- 636}, year = {2020}, abstract = {One of the most commonly used bonds between two biomolecules is the bond between biotin and streptavidin (SA) or streptavidin homologues (SAHs). A high dissociation constant and the consequent high-temperature stability even allows for its use in nucleic acid detection under polymerase chain reaction (PCR) conditions. There are a number of SAHs available, and for assay design, it is of great interest to determine as to which SAH will perform the best under assay conditions. Although there are numerous single studies on the characterization of SAHs in solution or selected solid phases, there is no systematic study comparing different SAHs for biomolecule-binding, hybridization, and PCR assays on solid phases. We compared streptavidin, core streptavidin, traptavidin, core traptavidin, neutravidin, and monomeric streptavidin on the surface of microbeads (10-15 mu m in diameter) and designed multiplex microbead-based experiments and analyzed simultaneously the binding of biotinylated oligonucleotides and the hybridization of oligonucleotides to complementary capture probes. We also bound comparably large DNA origamis to capture probes on the microbead surface. We used a real-time fluorescence microscopy imaging platform, with which it is possible to subject samples to a programmable time and temperature profile and to record binding processes on the microbead surface depending on the time and temperature. With the exception of core traptavidin and monomeric streptavidin, all other SA/SAHs were suitable for our investigations. We found hybridization efficiencies close to 100\% for streptavidin, core streptavidin, traptavidin, and neutravidin. These could all be considered equally suitable for hybridization, PCR applications, and melting point analysis. The SA/SAH-biotin bond was temperature sensitive when the oligonucleotide was mono-biotinylated, with traptavidin being the most stable followed by streptavidin and neutravidin. Mono-biotinylated oligonucleotides can be used in experiments with temperatures up to 70 degrees C. When oligonucleotides were bis-biotinylated, all SA/SAH-biotin bonds had similar temperature stability under PCR conditions, even if they comprised a streptavidin variant with slower biotin dissociation and increased mechanostability.}, language = {en} } @article{SchmidtRoedigerGruneretal.2016, author = {Schmidt, Carsten and Roediger, Stefan and Gruner, Melanie and Moncsek, Anja and Stohwasser, Ralf and Hanack, Katja and Schierack, Peter and Schroeder, Christian}, title = {Multiplex localization of sequential peptide epitopes by use of a planar microbead chip}, series = {Analytica chimica acta : an international journal devoted to all branches of analytical chemistry}, volume = {908}, journal = {Analytica chimica acta : an international journal devoted to all branches of analytical chemistry}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0003-2670}, doi = {10.1016/j.aca.2015.12.030}, pages = {150 -- 160}, year = {2016}, abstract = {Epitope mapping is crucial for the characterization of protein-specific antibodies. Commonly, small overlapping peptides are chemically synthesized and immobilized to determine the specific peptide sequence. In this study, we report the use of a fast and inexpensive planar microbead chip for epitope mapping. We developed a generic strategy for expressing recombinant peptide libraries instead of using expensive synthetic peptide libraries. A biotin moiety was introduced in vivo at a defined peptide position using biotin ligase. Peptides in crude Escherichia coli lysate were coupled onto streptavidin-coated microbeads by incubation, thereby avoiding tedious purification procedures. For read-out we used a multiplex planar microbead chip with size- and fluorescence-encoded microbead populations. For epitope mapping, up to 18 populations of peptide-loaded microbeads (at least 20 microbeads per peptide) displaying the primary sequence of a protein were analyzed simultaneously. If an epitope was recognized by an antibody, a secondary fluorescence-labeled antibody generated a signal that was quantified, and the mean value of all microbeads in the population was calculated. We mapped the epitopes for rabbit anti-PA28 gamma (proteasome activator 28 gamma) polyclonal serum, for a murine monoclonal antibody against PA28 gamma, and for a murine monoclonal antibody against the hamster polyoma virus major capsid protein VP1 as models. In each case, the identification of one distinct peptide sequence out of up to 18 sequences was possible. Using this approach, an epitope can be mapped multiparametrically within three weeks. (C) 2016 Elsevier B.V. All rights reserved.}, language = {en} } @article{BergnerTaraschewskiSchroeder2015, author = {Bergner, Nadine and Taraschewski, Christian and Schroeder, Ulrik}, title = {Beispiel eines Sch{\"u}lerwettbewerbs zum Thema Projektmanagement und App-Programmierung}, series = {HDI 2014 : Gestalten von {\"U}berg{\"a}ngen}, volume = {2015}, journal = {HDI 2014 : Gestalten von {\"U}berg{\"a}ngen}, number = {9}, editor = {Schubert, Sigrid and Schwill, Andreas}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-84726}, pages = {161 -- 168}, year = {2015}, abstract = {Es wird ein Informatik-Wettbewerb f{\"u}r Sch{\"u}lerinnen und Sch{\"u}ler der Sekundarstufe II beschrieben, der {\"u}ber mehrere Wochen m{\"o}glichst realit{\"a}tsnah die Arbeitswelt eines Informatikers vorstellt. Im Wettbewerb erarbeiten die Sch{\"u}lerteams eine Android-App und organisieren ihre Entwicklung durch Projektmanagementmethoden, die sich an professionellen, agilen Prozessen orientieren. Im Beitrag werden der theoretische Hintergrund zu Wettbewerben, die organisatorischen und didaktischen Entscheidung, eine erste Evaluation sowie Reflexion und Ausblick dargestellt.}, language = {de} } @article{HurtienneSchroederSpannagel2015, author = {Hurtienne, Dominik and Schroeder, Ulrik and Spannagel, Christian}, title = {IT EnGAGES!}, series = {HDI 2014 : Gestalten von {\"U}berg{\"a}ngen}, volume = {2015}, journal = {HDI 2014 : Gestalten von {\"U}berg{\"a}ngen}, number = {9}, editor = {Schwill, Andreas and Schubert, Sigrid}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-80258}, pages = {27 -- 43}, year = {2015}, abstract = {Durch den Einsatz von Spielen und Spielelementen in Lernkontexten wird versucht, Lernende zur Besch{\"a}ftigung mit den Lerninhalten zu motivieren. Spielerische Elemente haben allerdings nicht nur positive motivationale Effekte: Sie k{\"o}nnen sich beispielsweise negativ auf die intrinsische Motivation auswirken, und auch nicht jeder Lernende spielt gerne. Um negativen Einfl{\"u}ssen von Gamification entgegenzuwirken, wurde ein Toolkit f{\"u}r adaptierbare Lernumgebungen entwickelt. Damit erzeugte Lernumgebungen erlauben es Studierenden, den Grad der Gamification selbst zu bestimmen, indem Spielelemente an- und abgeschaltet werden. Im Rahmen einer Anf{\"a}ngerprogrammiervorlesung wurden Lernspielaufgaben aus den existierenden, optionalen interaktiven eTests entwickelt und Studierenden als zus{\"a}tzliche Lerngelegenheit angeboten. Eine erste explorative Studie best{\"a}tigt die Vermutung, dass die Akzeptanz des adaptierbaren Lernspiels sehr hoch ist, es aber dennoch Studierende gibt, welche die Lernumgebung ohne Spielelemente durcharbeiten. Somit bietet adaptierbare Gamification verschiedenen Studierenden die M{\"o}glichkeit, sich zus{\"a}tzliche motivationale Anreize durch Zuschalten von Spielelementen zu verschaffen, ohne dabei zum Spielen „gen{\"o}tigt" zu werden.}, language = {de} } @article{AhnenAnsoldiAntonellietal.2018, author = {Ahnen, M. L. and Ansoldi, S. and Antonelli, L. A. and Arcaro, C. and Babie, A. and Banerjee, B. and Bangale, P. and de Almeida, U. Barres and Barrio, J. A. and Gonzalez, J. Becerra and Bednarek, W. and Bernardini, E. and Berti, A. and Biasuzzi, B. and Biland, A. and Blanch, O. and Bonnefoy, S. and Bonnoli, G. and Borracci, F. and Carosi, R. and Carosi, A. and Chatterjee, A. and Colin, P. and Colombo, E. and Contreras, J. L. and Cortina, J. and Covino, S. and Cumani, P. and Da Vela, P. and Dazzi, F. and De Angelis, A. and De Lotto, B. and Wilhelmi, E. de Ona and Di Pierro, F. and Doert, M. and Dominguez, A. and Prester, D. Dominis and Dorner, D. and Doro, M. and Einecke, S. and Glawion, D. Eisenacher and Elsaesser, D. and Engelkemeier, M. and Ramazani, V. Fallah and Fernandez-Barra, A. and Fidalgo, D. and Fonseca, M. V. and Font, L. and Fruck, C. and Galindo, D. and Lopez, R. J. Garcia and Garczarczyk, M. and Gaug, M. and Giammaria, P. and Godinovie, N. and Gora, D. and Griffiths, S. and Guberman, D. and Hadasch, D. and Hahn, A. and Hassan, T. and Hayashida, M. and Herrera, J. and Hose, J. and Hrupec, D. and Hughes, G. and Ishio, K. and Konno, Y. and Kubo, H. and Kushida, J. and Kuvezdie, D. and Lelas, D. and Lindfors, E. and Lombardi, S. and Longo, F. and Lopez, M. and Lopez-Oramas, A. and Majumdar, P. and Makariev, M. and Maneva, G. and Manganaro, M. and Mannheim, K. and Maraschi, L. and Mariotti, M. and Martinez, M. and Mazin, D. and Menzel, U. and Minev, M. and Mirzoyan, R. and Moralejo, A. and Moreno, V. and Moretti, E. and Munar-Adrover, P. and Neustroev, V. and Niedzwiecki, A. and Rosillo, M. Nievas and Nilsson, K. and Nishijima, K. and Noda, K. and Nogues, L. and Paiano, S. and Palacio, J. and Paneque, D. and Paoletti, R. and Paredes, J. M. and Paredes-Fortuny, X. and Pedaletti, G. and Peresano, M. and Perri, L. and Persic, M. and Moroni, P. G. Prada and Prandini, E. and Puljak, I. and Garcia, J. R. and Reichardt, I. and Rhode, W. and Riti, M. and Rico, J. and Saito, T. and Satalecka, K. and Schroeder, S. and Schweizer, T. and Shore, S. N. and Sillanpaa, A. and Sitarek, J. and Sobczynskall, D. and Stamerra, A. and Strzys, M. and Surie, T. and Takalo, L. and Tavecchio, F. and Temnikov, P. and Terzie, T. and Tescaro, D. and Teshima, M. and Torres, D. F. and Torres-Alla, N. and Treves, A. and Vanzo, G. and Acosta, M. Vazquez and Vovk, I. and Ward, J. E. and Will, M. and Wu, M. H. and Zarie, D. and Abdalla, Hassan E. and Abramowski, A. and Aharonian, Felix A. and Benkhali, F. Ait and Akhperjanian, A. G. and Andersson, T. and Ang{\"u}ner, Ekrem Oǧuzhan and Arakawa, M. and Arrieta, M. and Aubert, P. and Backes, M. and Balzer, A. and Barnard, M. and Becherini, Y. and Tjus, J. Becker and Berge, D. and Bernhard, S. and Bernlohr, K. and Blackwell, R. and Bottcher, M. and Boisson, C. and Bolmont, J. and Bordas, Pol and Bregeon, J. and Brun, F. and Brun, P. and Bryan, M. and Btichele, M. and Bulik, T. and Capasso, M. and Carr, J. and Casanova, Sabrina and Cerruti, M. and Chakraborty, N. and Chalme-Calvet, R. and Chaves, R. C. G. and Chen, A. and Chevalier, J. and Chretien, M. and Coffaro, M. and Colafrancesco, S. and Cologna, G. and Condon, B. and Conrad, J. and Cui, Y. and Davids, I. D. and Decock, J. and Degrange, B. and Dei, C. and Devin, J. and Dewilt, P. and Dirson, L. and Djannati-Atai, A. and Domainko, W. and Donath, A. and Dutson, K. and Dyks, J. and Edwards, T. and Egberts, Kathrin and Eger, P. and Ernenwein, J. -P. and Eschbach, S. and Farnier, C. and Fegan, S. and Fernandes, M. V. and Fiasson, A. and Fontaine, G. and Forster, A. and Funk, S. and Ftifiling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschal, D. and Goya, A. and Grondin, M. -H. and Hahn, J. and Haupt, M. and Hawkes, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hinton, J. A. and Hofmann, W. and Hoischen, Clemens and Holler, M. and Horns, D. and Ivascenko, A. and Iwasaki, H. and Jacholkowska, A. and Jamrozy, M. and Janiak, M. and Jankowsky, D. and Jankowsky, F. and Jingo, M. and Jogler, T. and Jouvin, L. and Jung-Richardt, I. and Kastendieck, M. A. and Katarzyfiski, K. and Katsuragawa, M. and Katz, U. and Kerszberg, D. and Khangulyan, D. and Khelifi, B. and Kieffer, M. and King, J. and Klepser, S. and Klochkov, D. and Kluiniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Kraus, M. and Krtiger, P. P. and Laffon, H. and Lamanna, G. and Lau, J. and Lees, J. -P. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Leser, Eva and Lohse, T. and Lorentz, M. and Liu, R. and Lopez-Coto, R. and Lypova, I. and Marandon, V. and Marcowith, Alexandre and Mariaud, C. and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and Meintjes, P. J. and Meyer, M. and Mitche, A. M. W. and Moderski, R. and Mohamed, M. and Mohrmann, L. and Mora, K. and Moulin, Emmanuel and Murach, T. and Nakashima, S. and De Naurois, M. and Niederwanger, F. and Niemiec, J. and Oakes, L. and Odaka, H. and Ott, S. and Ohm, S. and Ostrowski, M. and Oya, I. and Padovani, M. and Panter, M. and Parsons, R. D. and Pekeur, N. W. and Pelletier, G. and Perennes, C. and Petrucci, P. -O. and Peyaud, B. and Pie, Q. and Pita, S. and Poon, H. and Prokhorov, D. and Prokoph, H. and Ptffilhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reimer, A. and Reimer, O. and Renaud, M. and De Los Reyes, R. and Richter, S. and Rieger, F. and Romoli, C. and Rowell, G. and Rudak, B. and Rulten, C. B. and Safi-Harb, S. and Sahakian, V. and Saito, S. and Salek, D. and Sanchez, D. A. and Santangelo, A. and Sasaki, M. and Schlickeiser, R. and Schtissler, F. and Schulz, A. and Schwanke, U. and Schwemmer, S. and Seglar-Arroyo, M. and Settimo, M. and Seyffert, A. S. and Shafi, N. and Shilon, I. and Simoni, R. and So, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stycz, K. and Sushch, I. and Takahashi, T. and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tibaldo, L. and Tiziani, D. and Tluczykont, M. and Trichard, C. and Tsuji, N. and Tuffs, R. and Uchiyama, Y. and Van der Walt, D. J. and Van Eldik, C. and Van Rensburg, C. and Van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voisin, F. and Vok, H. J. and Vuillaume, T. and Wadiasingh, Z. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and White, R. and Wierzcholska, A. and Willmann, P. and Wornlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zanin, R. and Zdziarski, A. A. and Zech, Alraune and Zefi, F. and Ziegler, A. and Zywuckan, N.}, title = {Constraints on particle acceleration in SS433/W50 from MAGIC and HESS observations}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {612}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, organization = {HESS Collaboratio MAGIC Collaboration}, issn = {1432-0746}, doi = {10.1051/0004-6361/201731169}, pages = {8}, year = {2018}, abstract = {Context. The large jet kinetic power and non-thermal processes occurring in the microquasar SS 433 make this source a good candidate for a very high-energy (VHE) gamma-ray emitter. Gamma-ray fluxes above the sensitivity limits of current Cherenkov telescopes have been predicted for both the central X-ray binary system and the interaction regions of SS 433 jets with the surrounding W50 nebula. Non-thermal emission at lower energies has been previously reported, indicating that efficient particle acceleration is taking place in the system. Aims. We explore the capability of SS 433 to emit VHE gamma rays during periods in which the expected flux attenuation due to periodic eclipses (P-orb similar to 13.1 days) and precession of the circumstellar disk (P-pre similar to 162 days) periodically covering the central binary system is expected to be at its minimum. The eastern and western SS 433/W50 interaction regions are also examined using the whole data set available. We aim to constrain some theoretical models previously developed for this system with our observations. Methods. We made use of dedicated observations from the Major Atmospheric Gamma Imaging Cherenkov telescopes (MAGIC) and High Energy Spectroscopic System (H.E.S.S.) of SS 433 taken from 2006 to 2011. These observation were combined for the first time and accounted for a total effective observation time of 16.5 h, which were scheduled considering the expected phases of minimum absorption of the putative VHE emission. Gamma-ray attenuation does not affect the jet/medium interaction regions. In this case, the analysis of a larger data set amounting to similar to 40-80 h, depending on the region, was employed. Results. No evidence of VHE gamma-ray emission either from the central binary system or from the eastern/western interaction regions was found. Upper limits were computed for the combined data set. Differential fluxes from the central system are found to be less than or similar to 10(-12)-10(-13) TeV-1 cm(-2) s(-1) in an energy interval ranging from similar to few x 100 GeV to similar to few TeV. Integral flux limits down to similar to 10(-12)-10(-13) ph cm(-2) s(-1) and similar to 10(-13)-10(-14) ph cm(-2) s(-1) are obtained at 300 and 800 GeV, respectively. Our results are used to place constraints on the particle acceleration fraction at the inner jet regions and on the physics of the jet/medium interactions. Conclusions. Our findings suggest that the fraction of the jet kinetic power that is transferred to relativistic protons must be relatively small in SS 433, q(p) <= 2.5 x 10(-5), to explain the lack of TeV and neutrino emission from the central system. At the SS 433/W50 interface, the presence of magnetic fields greater than or similar to 10 mu G is derived assuming a synchrotron origin for the observed X-ray emission. This also implies the presence of high-energy electrons with E-e up to 50 TeV, preventing an efficient production of gamma-ray fluxes in these interaction regions.}, language = {en} } @article{JeltschBlaumBroseetal.2013, author = {Jeltsch, Florian and Blaum, Niels and Brose, Ulrich and Chipperfield, Joseph D. and Clough, Yann and Farwig, Nina and Geissler, Katja and Graham, Catherine H. and Grimm, Volker and Hickler, Thomas and Huth, Andreas and May, Felix and Meyer, Katrin M. and Pagel, J{\"o}rn and Reineking, Bj{\"o}rn and Rillig, Matthias C. and Shea, Katriona and Schurr, Frank Martin and Schroeder, Boris and Tielb{\"o}rger, Katja and Weiss, Lina and Wiegand, Kerstin and Wiegand, Thorsten and Wirth, Christian and Zurell, Damaris}, title = {How can we bring together empiricists and modellers in functional biodiversity research?}, series = {Basic and applied ecology : Journal of the Gesellschaft f{\"u}r {\"O}kologie}, volume = {14}, journal = {Basic and applied ecology : Journal of the Gesellschaft f{\"u}r {\"O}kologie}, number = {2}, publisher = {Elsevier}, address = {Jena}, issn = {1439-1791}, doi = {10.1016/j.baae.2013.01.001}, pages = {93 -- 101}, year = {2013}, abstract = {Improving our understanding of biodiversity and ecosystem functioning and our capacity to inform ecosystem management requires an integrated framework for functional biodiversity research (FBR). However, adequate integration among empirical approaches (monitoring and experimental) and modelling has rarely been achieved in FBR. We offer an appraisal of the issues involved and chart a course towards enhanced integration. A major element of this path is the joint orientation towards the continuous refinement of a theoretical framework for FBR that links theory testing and generalization with applied research oriented towards the conservation of biodiversity and ecosystem functioning. We further emphasize existing decision-making frameworks as suitable instruments to practically merge these different aims of FBR and bring them into application. This integrated framework requires joint research planning, and should improve communication and stimulate collaboration between modellers and empiricists, thereby overcoming existing reservations and prejudices. The implementation of this integrative research agenda for FBR requires an adaptation in most national and international funding schemes in order to accommodate such joint teams and their more complex structures and data needs.}, language = {en} }