@book{HoltmannHoltmannGoerletal.2004, author = {Holtmann, Dieter and Holtmann, Elisabeth and G{\"o}rl, Tilo and Goltz, Elke and Fischer, Ulrike and Janeczka, Ines and Jacobi, Lena and Otto, Christian and Klauß, Christian and Hoffmann, Juliane and Tinsner, Karen and Patzwald, Claudia and Buchheister, Claudia and Bsdok, Ursula and Christ, Mirja and Elsner, Anne and Hagenm{\"u}ller, Jan-Peter and Kellner, Andreas}, title = {Gewalt und Fremdenfeindlichkeit : Erkl{\"a}rungsfaktoren sowie Handlungsempfehlungen zu den kriminalpr{\"a}ventiven und zivilgesellschaftlichen Potentialen}, publisher = {Landespr{\"a}ventionsrat Potsdam}, address = {Potsdam}, pages = {76 S.}, year = {2004}, language = {de} } @techreport{ThiekenDierckDunstetal.2018, author = {Thieken, Annegret and Dierck, Julia and Dunst, Lea and G{\"o}pfert, Christian and Heidenreich, Anna and Hetz, Karen and Kern, Julia and Kern, Kristine and Lipp, Torsten and Lippert, Cordine and Meves, Monika and Niederhafner, Stefan and Otto, Antje and Rohrbacher, Christian and Schmidt, Katja and Strate, Leander and Stumpp, Inga and Walz, Ariane}, title = {Urbane Resilienz gegen{\"u}ber extremen Wetterereignissen - Typologien und Transfer von Anpassungsstrategien in kleinen Großst{\"a}dten und Mittelst{\"a}dten (ExTrass)}, organization = {Leibniz-Institut f{\"u}r Raumbezogene Sozialforschung, adelphi research gGmbH}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-416067}, pages = {102}, year = {2018}, abstract = {Weltweit verursachen St{\"a}dte etwa 70 \% der Treibhausgasemissionen und sind daher wichtige Akteure im Klimaschutz bzw. eine wichtige Zielgruppe von Klimapolitiken. Gleichzeitig sind St{\"a}dte besonders stark von m{\"o}glichen Auswirkungen des Klimawandels betroffen: Insbesondere extreme Wetterereignisse wie Hitzewellen oder Starkregenereignisse mit {\"U}berflutungen verursachen in St{\"a}dten hohe Sachsch{\"a}den und wirken sich negativ auf die Gesundheit der st{\"a}dtischen Bev{\"o}lkerung aus. Daher verfolgt das Projekt ExTrass das Ziel, die st{\"a}dtische Resilienz gegen{\"u}ber extremen Wetterereignissen in enger Zusammenarbeit mit Stadtverwaltungen, Strukturen des Bev{\"o}lkerungsschutzes und der Zivilgesellschaft zu st{\"a}rken. Im Fokus stehen dabei (kreisfreie) Groß- und Mittelst{\"a}dte mit 50.000 bis 500.000 Einwohnern, insbesondere die Fallstudienst{\"a}dte Potsdam, Remscheid und W{\"u}rzburg. Der vorliegende Bericht beinhaltet die Ergebnisse der 14-monatigen Definitionsphase von ExTrass, in der vor allem die Abstimmung eines Arbeitsprogramms im Mittelpunkt stand, das in einem nachfolgenden dreij{\"a}hrigen Forschungsprojekt (F+E-Phase) gemeinsam von Wissenschaft und Praxispartnern umgesetzt werden soll. Begleitend wurde eine Bestandsaufnahme von Klimaanpassungs- und Klimaschutzstrategien/-pl{\"a}nen in 99 deutschen Groß- und Mittelst{\"a}dten vorgenommen. Zudem wurden f{\"u}r Potsdam und W{\"u}rzburg Pfadanalysen f{\"u}r die Klimapolitik durchgef{\"u}hrt. Darin wird insbesondere die Bedeutung von Schl{\"u}sselakteuren deutlich. Weiterhin wurden im Rahmen von Stakeholder-Workshops Anpassungsherausforderungen und aktuelle Handlungsbedarfe in den Fallstudienst{\"a}dten identifiziert und L{\"o}sungsans{\"a}tze erarbeitet, die in der F+E-Phase entwickelt und getestet werden sollen. Neben Maßnahmen auf gesamtst{\"a}dtischer Ebene und auf Stadtteilebene wurden Maßnahmen angestrebt, die die Risikowahrnehmung, Vorsorge und Selbsthilfef{\"a}higkeit von Unternehmen und Bev{\"o}lkerung st{\"a}rken k{\"o}nnen. Daher wurde der Stand der Risikokommunikation in Deutschland f{\"u}r das Projekt aufgearbeitet und eine erste Evaluation von Risikokommunikationswerkzeugen durchgef{\"u}hrt. Der Bericht endet mit einer Kurzfassung des Arbeitsprogramms 2018-2021.}, language = {de} } @book{StillmarkLimbergGoetzmannetal.2020, author = {Stillmark, Hans-Christian and Limberg, J{\"o}rg and G{\"o}tzmann, Jutta and Vogt, Jochen and Eke, Norbert Otto and Braun, Matthias and Clare, Jennifer and Grimm, Christa and Hofmann, Michael and Bauer, Gerhard and Starke, Frank}, title = {Peter Weiss erinnernd - Ansichten und Einsichten}, editor = {Stillmark, Hans-Christian}, edition = {150}, publisher = {Weidler Buchverlag}, address = {Berlin}, isbn = {978-3-89693-747-6}, publisher = {Universit{\"a}t Potsdam}, pages = {157}, year = {2020}, abstract = {Der Band versammelt verschiedenen Beitr{\"a}ge, die sich mit dem Leben und Werk von Peter Weiss auseinandersetzen. Die Beitr{\"a}ge wurden auf der Konferenz "Peter Weiss - 100" anl{\"a}ßlich des hundertsten Geburtstages des Autors im Jahre 2016 in Potsdam gehalten. Dabei wirkten unterschiedliche Einrichtungen und Institutionen erstmals gemeinsam im Geburtsort des K{\"u}nstlers.}, language = {de} } @article{OttoMareljaSchoofsetal.2018, author = {Otto, Nils and Marelja, Zvonimir and Schoofs, Andreas and Kranenburg, Holger and Bittern, Jonas and Yildirim, Kerem and Berh, Dimitri and Bethke, Maria and Thomas, Silke and Rode, Sandra and Risse, Benjamin and Jiang, Xiaoyi and Pankratz, Michael and Leimk{\"u}hler, Silke and Kl{\"a}mbt, Christian}, title = {The sulfite oxidase Shopper controls neuronal activity by regulating glutamate homeostasis in Drosophila ensheathing glia}, series = {Nature Communications}, volume = {9}, journal = {Nature Communications}, publisher = {Nature Publ. Group}, address = {London}, issn = {2041-1723}, doi = {10.1038/s41467-018-05645-z}, pages = {12}, year = {2018}, abstract = {Specialized glial subtypes provide support to developing and functioning neural networks. Astrocytes modulate information processing by neurotransmitter recycling and release of neuromodulatory substances, whereas ensheathing glial cells have not been associated with neuromodulatory functions yet. To decipher a possible role of ensheathing glia in neuronal information processing, we screened for glial genes required in the Drosophila central nervous system for normal locomotor behavior. Shopper encodes a mitochondrial sulfite oxidase that is specifically required in ensheathing glia to regulate head bending and peristalsis. shopper mutants show elevated sulfite levels affecting the glutamate homeostasis which then act on neuronal network function. Interestingly, human patients lacking the Shopper homolog SUOX develop neurological symptoms, including seizures. Given an enhanced expression of SUOX by oligodendrocytes, our findings might indicate that in both invertebrates and vertebrates more than one glial cell type may be involved in modulating neuronal activity.}, language = {en} } @article{WalzBaumannKrachetal.2006, author = {Walz, Bernd and Baumann, Otto and Krach, Christian and Baumann, Arnd and Blenau, Wolfgang}, title = {The aminergic control of cockroach salivary glands}, year = {2006}, abstract = {The acinar salivary glands of cockroaches receive a dual innervation from the subesophageal ganglion and the stomatogastric nervous system. Acinar cells are surrounded by a plexus of dopaminergic and serotonergic varicose fibers. In addition, seroton-ergic terminals lie deep in the extracellulor spaces between acinar cells. Excitation-secretion coupling in cockroach salivary glands is stimulated by both dopamine and serotonin. These monoamines cause increases in the intracellular concentrations of cAMP and Ca2+. Stimulation of the glands by serotonin results in the production of a protein-rich saliva, whereas stimulation by dopamine results in saliva that is protein-free. Thus, two elementary secretary processes, namely electrolyte/water secretion and protein secretion, are triggered by different aminergic transmitters. Because of its simplicity and experimental accessibility, cockroach salivary glands have been used extensively as a model system to study the cellular actions of biogenic amines and to examine the pharmacological properties of biogenic amine receptors. In this review, we summarize current knowledge concerning the aminergic control of cockroach salivary glands and discuss our efforts to characterize Periplaneta biogenic amine receptors molecularly}, language = {en} } @book{BarceloEdelmayerGuichardetal.2004, author = {Barcel{\´o}, Pedro and Edelmayer, Friedrich and Guichard, Pierre and Herold-Schmidt, Hedwig and Kleinmann, Hans-Otto and Martin, Jose L.Martin and Schmidt, Peer and Windler, Christian}, title = {Kleine Geschichte Spaniens}, series = {Universal-Bibliothek}, volume = {17039}, journal = {Universal-Bibliothek}, editor = {Schmidt, Peer}, publisher = {Reclam}, address = {Stuttgart}, isbn = {3-15-017039-7}, pages = {555 S.}, year = {2004}, language = {de} } @misc{OttoMareljaSchoofsetal.2018, author = {Otto, Nils and Marelja, Zvonimir and Schoofs, Andreas and Kranenburg, Holger and Bittern, Jonas and Yildirim, Kerem and Berh, Dimitri and Bethke, Maria and Thomas, Silke and Rode, Sandra and Risse, Benjamin and Jiang, Xiaoyi and Pankratz, Michael and Leimk{\"u}hler, Silke and Kl{\"a}mbt, Christian}, title = {The sulfite oxidase Shopper controls neuronal activity by regulating glutamate homeostasis in Drosophila ensheathing glia}, series = {Postprints der Universit{\"a}t Potsdam : Mathematisch Naturwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch Naturwissenschaftliche Reihe}, number = {975}, issn = {1866-8372}, doi = {10.25932/publishup-42620}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-426205}, pages = {14}, year = {2018}, abstract = {Specialized glial subtypes provide support to developing and functioning neural networks. Astrocytes modulate information processing by neurotransmitter recycling and release of neuromodulatory substances, whereas ensheathing glial cells have not been associated with neuromodulatory functions yet. To decipher a possible role of ensheathing glia in neuronal information processing, we screened for glial genes required in the Drosophila central nervous system for normal locomotor behavior. Shopper encodes a mitochondrial sulfite oxidase that is specifically required in ensheathing glia to regulate head bending and peristalsis. shopper mutants show elevated sulfite levels affecting the glutamate homeostasis which then act on neuronal network function. Interestingly, human patients lacking the Shopper homolog SUOX develop neurological symptoms, including seizures. Given an enhanced expression of SUOX by oligodendrocytes, our findings might indicate that in both invertebrates and vertebrates more than one glial cell type may be involved in modulating neuronal activity.}, language = {en} } @article{HeneghanWardPereraetal.2012, author = {Heneghan, Carl and Ward, Alison and Perera, Rafael and Bankhead, Clare and Fuller, Alice and Stevens, Richard and Bradford, Kairen and Tyndel, Sally and Alonso-Coello, Pablo and Ansell, Jack and Beyth, Rebecca and Bernardo, Artur and Christensen, Thomas Decker and Cromheecke, Manon and Edson, Robert G and Fitzmaurice, David and Gadisseur, Alain PA and Garcia-Alamino, Josep M and Gardiner, Chris and Hasenkam, Michael and Jacobson, Alan and Kaatz, Scott and Kamali, Farhad and Khan, Tayyaba Irfan and Knight, Eve and Kortke, Heinrich and Levi, Marcel and Matchar, David Bruce and Menendez-Jandula, Barbara and Rakovac, Ivo and Schaefer, Christian and Siebenhofer, Andrea and Souto, Juan Carlos and Sunderji, Rubina and Gin, Kenneth and Shalansky, Karen and V{\"o}ller, Heinz and Wagner, Otto and Zittermann, Armin}, title = {Self-monitoring of oral anticoagulation systematic review and meta-analysis of individual patient data}, series = {The lancet}, volume = {379}, journal = {The lancet}, number = {9813}, publisher = {Elsevier}, address = {New York}, organization = {Self-Monitoring Trialist Collabora}, issn = {0140-6736}, doi = {10.1016/S0140-6736(11)61294-4}, pages = {322 -- 334}, year = {2012}, abstract = {Background Uptake of self-testing and self-management of oral coagulation has remained inconsistent, despite good evidence of their effectiveness. To clarify the value of self-monitoring of oral anticoagulation, we did a meta-analysis of individual patient data addressing several important gaps in the evidence, including an estimate of the effect on time to death, first major haemorrhage, and thromboembolism. Methods We searched Ovid versions of Embase (1980-2009) and Medline (1966-2009), limiting searches to randomised trials with a maximally sensitive strategy. We approached all authors of included trials and requested individual patient data: primary outcomes were time to death, first major haemorrhage, and first thromboembolic event. We did prespecified subgroup analyses according to age, type of control-group care (anticoagulation-clinic care vs primary care), self-testing alone versus self-management, and sex. We analysed patients with mechanical heart valves or atrial fibrillation separately. We used a random-effect model method to calculate pooled hazard ratios and did tests for interaction and heterogeneity, and calculated a time-specific number needed to treat. Findings Of 1357 abstracts, we included 11 trials with data for 6417 participants and 12 800 person-years of follow-up. We reported a significant reduction in thromboembolic events in the self-monitoring group (hazard ratio 0.51; 95\% CI 0.31-0.85) but not for major haemorrhagic events (0.88, 0.74-1.06) or death (0.82, 0.62-1.09). Participants younger than 55 years showed a striking reduction in thrombotic events (hazard ratio 0.33, 95\% CI 0.17-0.66), as did participants with mechanical heart valve (0.52, 0.35-0.77). Analysis of major outcomes in the very elderly (age >= 85 years, n=99) showed no significant adverse effects of the intervention for all outcomes. Interpretation Our analysis showed that self-monitoring and self-management of oral coagulation is a safe option for suitable patients of all ages. Patients should also be offered the option to self-manage their disease with suitable health-care support as back-up.}, language = {en} } @misc{OttoPiontekKalkuhletal.2020, author = {Otto, Christian and Piontek, Franziska and Kalkuhl, Matthias and Frieler, Katja}, title = {Event-based models to understand the scale of the impact of extremes}, series = {Nature energy}, volume = {5}, journal = {Nature energy}, number = {2}, publisher = {Nature Publishing Group}, address = {London}, issn = {2058-7546}, doi = {10.1038/s41560-020-0562-4}, pages = {111 -- 114}, year = {2020}, abstract = {Climate change entails an intensification of extreme weather events that can potentially trigger socioeconomic and energy system disruptions. As we approach 1 degrees C of global warming we should start learning from historical extremes and explicitly incorporate such events in integrated climate-economy and energy systems models.}, language = {en} } @misc{KruegerSchwarzeBaumannetal.2018, author = {Kr{\"u}ger, Stefanie and Schwarze, Michael and Baumann, Otto and G{\"u}nter, Christina and Bruns, Michael and K{\"u}bel, Christian and Szab{\´o}, Doroth{\´e}e Vinga and Meinusch, Rafael and de Zea Bermudez, Ver{\´o}nica and Taubert, Andreas}, title = {Bombyx mori silk/titania/gold hybrid materials for photocatalytic water splitting}, series = {Postprints der Universit{\"a}t Potsdam Mathematisch-Naturwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam Mathematisch-Naturwissenschaftliche Reihe}, number = {581}, issn = {1866-8372}, doi = {10.25932/publishup-42349}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-423499}, pages = {18}, year = {2018}, abstract = {The synthesis, structure, and photocatalytic water splitting performance of two new titania (TiO 2 )/gold(Au)/Bombyx mori silk hybrid materials are reported. All materials are monoliths with diameters of up to ca. 4.5 cm. The materials are macroscopically homogeneous and porous with surface areas between 170 and 210 m 2/g. The diameter of the TiO 2 nanoparticles (NPs) - mainly anatase with a minor fraction of brookite - and the Au NPs are on the order of 5 and 7-18 nm, respectively. Addition of poly(ethylene oxide) to the reaction mixture enables pore size tuning, thus providing access to different materials with different photocatalytic activities. Water splitting experiments using a sunlight simulator and a Xe lamp show that the new hybrid materials are effective water splitting catalysts and produce up to 30 mmol of hydrogen per 24 h. Overall the article demonstrates that the combination of a renewable and robust scaffold such as B. mori silk with a photoactive material provides a promising approach to new monolithic photocatalysts that can easily be recycled and show great potential for application in lightweight devices for green fuel production.}, language = {en} } @article{MadrugadeBritoOttoKuhlicke2021, author = {Madruga de Brito, Mariana and Otto, Danny and Kuhlicke, Christian}, title = {Tracking topics and frames regarding sustainability transformations during the onset of the COVID-19 crisis}, series = {Sustainability / Multidisciplinary Digital Publishing Institute (MDPI)}, volume = {13}, journal = {Sustainability / Multidisciplinary Digital Publishing Institute (MDPI)}, number = {19}, publisher = {MDPI}, address = {Basel}, issn = {2071-1050}, doi = {10.3390/su131911095}, pages = {19}, year = {2021}, abstract = {Many researchers and politicians believe that the COVID-19 crisis may have opened a "window of opportunity " to spur sustainability transformations. Still, evidence for such a dynamic is currently lacking. Here, we propose the linkage of "big data " and "thick data " methods for monitoring debates on transformation processes by following the COVID-19 discourse on ecological sustainability in Germany. We analysed variations in the topics discussed by applying text mining techniques to a corpus with 84,500 newspaper articles published during the first COVID-19 wave. This allowed us to attain a unique and previously inaccessible "bird's eye view " of how these topics evolved. To deepen our understanding of prominent frames, a qualitative content analysis was undertaken. Furthermore, we investigated public awareness by analysing online search behaviour. The findings show an underrepresentation of sustainability topics in the German news during the early stages of the crisis. Similarly, public awareness regarding climate change was found to be reduced. Nevertheless, by examining the newspaper data in detail, we found that the pandemic is often seen as a chance for sustainability transformations-but not without a set of challenges. Our mixed-methods approach enabled us to bridge knowledge gaps between qualitative and quantitative research by "thickening " and providing context to data-driven analyses. By monitoring whether or not the current crisis is seen as a chance for sustainability transformations, we provide insights for environmental policy in times of crisis.}, language = {en} } @article{KruegerSchwarzeBaumannetal.2018, author = {Kr{\"u}ger, Stefanie and Schwarze, Michael and Baumann, Otto and G{\"u}nter, Christina and Bruns, Michael and K{\"u}bel, Christian and Szabo, Dorothee Vinga and Meinusch, Rafael and Bermudez, Veronica de Zea and Taubert, Andreas}, title = {Bombyx mori silk/titania/gold hybrid materials for photocatalytic water splitting}, series = {Beilstein journal of nanotechnology}, volume = {9}, journal = {Beilstein journal of nanotechnology}, publisher = {Beilstein-Institut zur F{\"o}rderung der Chemischen Wissenschaften}, address = {Frankfurt, Main}, issn = {2190-4286}, doi = {10.3762/bjnano.9.21}, pages = {187 -- 204}, year = {2018}, abstract = {The synthesis, structure, and photocatalytic water splitting performance of two new titania (TiO2)/gold(Au)/Bombyx mori silk hybrid materials are reported. All materials are monoliths with diameters of up to ca. 4.5 cm. The materials are macroscopically homogeneous and porous with surface areas between 170 and 210 m(2)/g. The diameter of the TiO2 nanoparticles (NPs) - mainly anatase with a minor fraction of brookite - and the Au NPs are on the order of 5 and 7-18 nm, respectively. Addition of poly(ethylene oxide) to the reaction mixture enables pore size tuning, thus providing access to different materials with different photocatalytic activities. Water splitting experiments using a sunlight simulator and a Xe lamp show that the new hybrid materials are effective water splitting catalysts and produce up to 30 mmol of hydrogen per 24 h. Overall the article demonstrates that the combination of a renewable and robust scaffold such as B. mori silk with a photoactive material provides a promising approach to new monolithic photocatalysts that can easily be recycled and show great potential for application in lightweight devices for green fuel production.}, language = {en} } @misc{WenzLevermannWillneretal.2020, author = {Wenz, Leonie and Levermann, Anders and Willner, Sven N. and Otto, Christian and Kuhla, Kilian}, title = {Post-Brexit no-trade-deal scenario: short-term consumer benefit at the expense of long-term economic development}, series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, number = {9}, issn = {1866-8372}, doi = {10.25932/publishup-52581}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-525819}, pages = {16}, year = {2020}, abstract = {After the United Kingdom has left the European Union it remains unclear whether the two parties can successfully negotiate and sign a trade agreement within the transition period. Ongoing negotiations, practical obstacles and resulting uncertainties make it highly unlikely that economic actors would be fully prepared to a "no-trade-deal" situation. Here we provide an economic shock simulation of the immediate aftermath of such a post-Brexit no-trade-deal scenario by computing the time evolution of more than 1.8 million interactions between more than 6,600 economic actors in the global trade network. We find an abrupt decline in the number of goods produced in the UK and the EU. This sudden output reduction is caused by drops in demand as customers on the respective other side of the Channel incorporate the new trade restriction into their decision-making. As a response, producers reduce prices in order to stimulate demand elsewhere. In the short term consumers benefit from lower prices but production value decreases with potentially severe socio-economic consequences in the longer term.}, language = {en} } @article{WillnerOttoLevermann2018, author = {Willner, Sven N. and Otto, Christian and Levermann, Anders}, title = {Global economic response to river floods}, series = {Nature climate change}, volume = {8}, journal = {Nature climate change}, number = {7}, publisher = {Nature Publ. Group}, address = {London}, issn = {1758-678X}, doi = {10.1038/s41558-018-0173-2}, pages = {594 -- 598}, year = {2018}, abstract = {Increasing Earth's surface air temperature yields an intensification of its hydrological cycle. As a consequence, the risk of river floods will increase regionally within the next two decades due to the atmospheric warming caused by past anthropogenic greenhouse gas emissions. The direct economic losses caused by these floods can yield regionally heterogeneous losses and gains by propagation within the global trade and supply network. Here we show that, in the absence of large-scale structural adaptation, the total economic losses due to fluvial floods will increase in the next 20 years globally by 17\% despite partial compensation through market adjustment within the global trade network. China will suffer the strongest direct losses, with an increase of 82\%. The United States is mostly affected indirectly through its trade relations. By contrast to the United States, recent intensification of the trade relations with China leaves the European Union better prepared for the import of production losses in the future.}, language = {en} } @article{WenzLevermannWillneretal.2020, author = {Wenz, Leonie and Levermann, Anders and Willner, Sven N. and Otto, Christian and Kuhla, Kilian}, title = {Post-Brexit no-trade-deal scenario: short-term consumer benefit at the expense of long-term economic development}, series = {PLoS ONE}, volume = {15}, journal = {PLoS ONE}, number = {9}, publisher = {PLOS}, address = {San Francisco}, pages = {14}, year = {2020}, abstract = {After the United Kingdom has left the European Union it remains unclear whether the two parties can successfully negotiate and sign a trade agreement within the transition period. Ongoing negotiations, practical obstacles and resulting uncertainties make it highly unlikely that economic actors would be fully prepared to a "no-trade-deal" situation. Here we provide an economic shock simulation of the immediate aftermath of such a post-Brexit no-trade-deal scenario by computing the time evolution of more than 1.8 million interactions between more than 6,600 economic actors in the global trade network. We find an abrupt decline in the number of goods produced in the UK and the EU. This sudden output reduction is caused by drops in demand as customers on the respective other side of the Channel incorporate the new trade restriction into their decision-making. As a response, producers reduce prices in order to stimulate demand elsewhere. In the short term consumers benefit from lower prices but production value decreases with potentially severe socio-economic consequences in the longer term.}, language = {en} } @article{MiddelanisWillnerOttoetal.2021, author = {Middelanis, Robin and Willner, Sven N. and Otto, Christian and Kuhla, Kilian and Quante, Lennart and Levermann, Anders}, title = {Wave-like global economic ripple response to Hurricane Sandy}, series = {Environmental research letters : ERL / Institute of Physics}, volume = {16}, journal = {Environmental research letters : ERL / Institute of Physics}, number = {12}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {1748-9326}, doi = {10.1088/1748-9326/ac39c0}, pages = {11}, year = {2021}, abstract = {Tropical cyclones range among the costliest disasters on Earth. Their economic repercussions along the supply and trade network also affect remote economies that are not directly affected. We here simulate possible global repercussions on consumption for the example case of Hurricane Sandy in the US (2012) using the shock-propagation model Acclimate. The modeled shock yields a global three-phase ripple: an initial production demand reduction and associated consumption price decrease, followed by a supply shortage with increasing prices, and finally a recovery phase. Regions with strong trade relations to the US experience strong magnitudes of the ripple. A dominating demand reduction or supply shortage leads to overall consumption gains or losses of a region, respectively. While finding these repercussions in historic data is challenging due to strong volatility of economic interactions, numerical models like ours can help to identify them by approaching the problem from an exploratory angle, isolating the effect of interest. For this, our model simulates the economic interactions of over 7000 regional economic sectors, interlinked through about 1.8 million trade relations. Under global warming, the wave-like structures of the economic response to major hurricanes like the one simulated here are likely to intensify and potentially overlap with other weather extremes.}, language = {en} } @article{OttoWillnerWenzetal.2017, author = {Otto, Christian and Willner, Sven N. and Wenz, Leonie and Frieler, Katja and Levermann, Anders}, title = {Modeling loss-propagation in the global supply network: The dynamic agent-based model acclimate}, series = {Journal of economic dynamics \& control}, volume = {83}, journal = {Journal of economic dynamics \& control}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0165-1889}, doi = {10.1016/j.jedc.2017.08.001}, pages = {232 -- 269}, year = {2017}, abstract = {World markets are highly interlinked and local economies extensively rely on global supply and value chains. Consequently, local production disruptions, for instance caused by extreme weather events, are likely to induce indirect losses along supply chains with potentially global repercussions. These complex loss dynamics represent a challenge for comprehensive disaster risk assessments. Here, we introduce the numerical agent-based model acclimate designed to analyze the cascading of economic losses in the global supply network. Using national sectors as agents, we apply the model to study the global propagation of losses induced by stylized disasters. We find that indirect losses can become comparable in size to direct ones, but can be efficiently mitigated by warehousing and idle capacities. Consequently, a comprehensive risk assessment cannot focus solely on first-tier suppliers, but has to take the whole supply chain into account. To render the supply network climate-proof, national adaptation policies have to be complemented by international adaptation efforts. In that regard, our model can be employed to assess reasonable leverage points and to identify dynamic bottlenecks inaccessible to static analyses. (C) 2017 Elsevier B.V. All rights reserved.}, language = {en} } @article{RudolphSchmeerGuentheretal.2021, author = {Rudolph, Max and Schmeer, Christian and G{\"u}nther, Madlen and Woitke, Florus and Kathner-Schaffert, Carolin and Karapetow, Lina and Lindner, Julia and Lehmann, Thomas and Jirikowski, Gustav and Witte, Otto W. and Redecker, Christoph and Keiner, Silke}, title = {Microglia-mediated phagocytosis of apoptotic nuclei is impaired in the adult murine hippocampus after stroke}, series = {Glia}, volume = {69}, journal = {Glia}, number = {8}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {0894-1491}, doi = {10.1002/glia.24009}, pages = {2006 -- 2022}, year = {2021}, abstract = {Following stroke, neuronal death takes place both in the infarct region and in brain areas distal to the lesion site including the hippocampus. The hippocampus is critically involved in learning and memory processes and continuously generates new neurons. Dysregulation of adult neurogenesis may be associated with cognitive decline after a stroke lesion. In particular, proliferation of precursor cells and the formation of new neurons are increased after lesion. Within the first week, many new precursor cells die during development. How dying precursors are removed from the hippocampus and to what extent phagocytosis takes place after stroke is still not clear. Here, we evaluated the effect of a prefrontal stroke lesion on the phagocytic activity of microglia in the dentate gyrus (DG) of the hippocampus. Three-months-old C57BL/6J mice were injected once with the proliferation marker BrdU (250 mg/kg) 6 hr after a middle cerebral artery occlusion or sham surgery. The number of apoptotic cells and the phagocytic capacity of the microglia were evaluated by means of immunohistochemistry, confocal microscopy, and 3D-reconstructions. We found a transient but significant increase in the number of apoptotic cells in the DG early after stroke, associated with impaired removal by microglia. Interestingly, phagocytosis of newly generated precursor cells was not affected. Our study shows that a prefrontal stroke lesion affects phagocytosis of apoptotic cells in the DG, a region distal to the lesion core. Whether disturbed phagocytosis might contribute to inflammatory- and maladaptive processes including cognitive impairment following stroke needs to be further investigated.}, language = {en} } @article{OttoGoepfertThieken2021, author = {Otto, Antje and G{\"o}pfert, Christian and Thieken, Annegret}, title = {Are cities prepared for climate change?}, series = {Mitigation and adaptation strategies for global change : an international journal devoted to scientific, engineering, socio-economic and policy responses to environmental change}, volume = {26}, journal = {Mitigation and adaptation strategies for global change : an international journal devoted to scientific, engineering, socio-economic and policy responses to environmental change}, number = {8}, publisher = {Springer}, address = {Dordrecht}, issn = {1381-2386}, doi = {10.1007/s11027-021-09971-4}, pages = {25}, year = {2021}, abstract = {Cities can be severely affected by climate change. Hence, many of them have started to develop climate adaptation strategies or implement measures to help prepare for the challenges it will present. This study aims to provide an overview of climate adaptation in 104 German cities. While existing studies on adaptation tracking rely heavily on self-reported data or the mere existence of adaptation plans, we applied the broader concept of adaptation readiness, considering five factors and a total of twelve different indicators, when making our assessments. We clustered the cities depending on the contribution of these factors to the overall adaptation readiness index and grouped them according to their total score and cluster affiliations. This resulted in us identifying four groups of cities. First, a pioneering group comprises twelve (mainly big) cities with more than 500,000 inhabitants, which showed high scores for all five factors of adaptation readiness. Second, a set of 36 active cities, which follow different strategies on how to deal with climate adaptation. Third, a group of 28 cities showed considerably less activity toward climate adaptation, while a fourth set of 28 mostly small cities (with between 50,000 and 99,999 inhabitants) scored the lowest. We consider this final group to be pursuing a 'wait-and-see' approach. Since the city size correlates with the adaptation readiness index, we recommend policymakers introduce funding schemes that focus on supporting small cities, to help them prepare for the impact of a changing climate.}, language = {en} } @misc{ThiekenKienzlerKreibichetal.2016, author = {Thieken, Annegret and Kienzler, Sarah and Kreibich, Heidi and Kuhlicke, Christian and Kunz, Michael and M{\"u}hr, Bernhard and M{\"u}ller, Meike and Otto, Antje and Petrow, Theresia and Pisi, Sebastian and Schr{\"o}ter, Kai}, title = {Review of the flood risk management system in Germany after the major flood in 2013}, issn = {1866-8372}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-100600}, pages = {12}, year = {2016}, abstract = {Widespread flooding in June 2013 caused damage costs of €6 to 8 billion in Germany, and awoke many memories of the floods in August 2002, which resulted in total damage of €11.6 billion and hence was the most expensive natural hazard event in Germany up to now. The event of 2002 does, however, also mark a reorientation toward an integrated flood risk management system in Germany. Therefore, the flood of 2013 offered the opportunity to review how the measures that politics, administration, and civil society have implemented since 2002 helped to cope with the flood and what still needs to be done to achieve effective and more integrated flood risk management. The review highlights considerable improvements on many levels, in particular (1) an increased consideration of flood hazards in spatial planning and urban development, (2) comprehensive property-level mitigation and preparedness measures, (3) more effective flood warnings and improved coordination of disaster response, and (4) a more targeted maintenance of flood defense systems. In 2013, this led to more effective flood management and to a reduction of damage. Nevertheless, important aspects remain unclear and need to be clarified. This particularly holds for balanced and coordinated strategies for reducing and overcoming the impacts of flooding in large catchments, cross-border and interdisciplinary cooperation, the role of the general public in the different phases of flood risk management, as well as a transparent risk transfer system. Recurring flood events reveal that flood risk management is a continuous task. Hence, risk drivers, such as climate change, land-use changes, economic developments, or demographic change and the resultant risks must be investigated at regular intervals, and risk reduction strategies and processes must be reassessed as well as adapted and implemented in a dialogue with all stakeholders.}, language = {en} } @book{ThiekenBesselCallsenetal.2015, author = {Thieken, Annegret and Bessel, Tina and Callsen, Ines and Falter, Daniela and Hasan, Issa and Kienzler, Sarah and Kox, Thomas and Kreibich, Heidi and Kuhlicke, Christian and Kunz, Michael and Matthias, Max and Meyer, Volker and M{\"u}hr, Bernhard and M{\"u}ller, Meike and Otto, Antje and Pech, Ina and Petrow, Theresia and Pisi, Sebastian and Rother, Karl-Heinz and Schr{\"o}ter, Kai}, title = {Das Hochwasser im Juni 2013}, series = {Schriftenreihe des DKKV ; 53}, journal = {Schriftenreihe des DKKV ; 53}, publisher = {Deutsches Komitee Katastrophenvorsorge}, address = {Bonn}, isbn = {978-3-933181-62-6}, publisher = {Universit{\"a}t Potsdam}, pages = {207}, year = {2015}, language = {de} } @article{ThiekenKienzlerKreibichetal.2016, author = {Thieken, Annegret and Kienzler, Sarah and Kreibich, Heidi and Kuhlicke, Christian and Kunz, Michael and M{\"u}hr, Bernhard and M{\"u}ller, Meike and Otto, Antje and Petrow, Theresia and Pisi, Sebastian and Schr{\"o}ter, Kai}, title = {Review of the flood risk management system in Germany after the major flood in 2013}, series = {Ecology and society : E\&S ; a journal of integrative science for resilience and sustainability}, volume = {21}, journal = {Ecology and society : E\&S ; a journal of integrative science for resilience and sustainability}, number = {2}, publisher = {Resilience Alliance}, address = {Wolfville, NS}, issn = {1708-3087}, doi = {10.5751/ES-08547-210251}, pages = {12}, year = {2016}, abstract = {Widespread flooding in June 2013 caused damage costs of €6 to 8 billion in Germany, and awoke many memories of the floods in August 2002, which resulted in total damage of €11.6 billion and hence was the most expensive natural hazard event in Germany up to now. The event of 2002 does, however, also mark a reorientation toward an integrated flood risk management system in Germany. Therefore, the flood of 2013 offered the opportunity to review how the measures that politics, administration, and civil society have implemented since 2002 helped to cope with the flood and what still needs to be done to achieve effective and more integrated flood risk management. The review highlights considerable improvements on many levels, in particular (1) an increased consideration of flood hazards in spatial planning and urban development, (2) comprehensive property-level mitigation and preparedness measures, (3) more effective flood warnings and improved coordination of disaster response, and (4) a more targeted maintenance of flood defense systems. In 2013, this led to more effective flood management and to a reduction of damage. Nevertheless, important aspects remain unclear and need to be clarified. This particularly holds for balanced and coordinated strategies for reducing and overcoming the impacts of flooding in large catchments, cross-border and interdisciplinary cooperation, the role of the general public in the different phases of flood risk management, as well as a transparent risk transfer system. Recurring flood events reveal that flood risk management is a continuous task. Hence, risk drivers, such as climate change, land-use changes, economic developments, or demographic change and the resultant risks must be investigated at regular intervals, and risk reduction strategies and processes must be reassessed as well as adapted and implemented in a dialogue with all stakeholders.}, language = {en} } @article{ThiekenOttoPisietal.2015, author = {Thieken, Annegret and Otto, Antje and Pisi, Sebastian and Petrow, Theresia and Kreibich, Heidi and Kuhlicke, Christian and Schr{\"o}ter, Kai and Kienzler, Sarah and M{\"u}ller, Meike}, title = {Schlussfolgerungen und Empfehlungen}, series = {Das Hochwasser im Juni 2013 : Bew{\"a}hrungsprobe f{\"u}r das Hochwasserrisikomanagement in Deutschland}, journal = {Das Hochwasser im Juni 2013 : Bew{\"a}hrungsprobe f{\"u}r das Hochwasserrisikomanagement in Deutschland}, publisher = {Deutsches Komitee Katastrophenvorsorge}, address = {Bonn}, isbn = {978-3-933181-62-6}, pages = {184 -- 196}, year = {2015}, language = {de} } @misc{ThiekenKienzlerKreibichetal.2016, author = {Thieken, Annegret and Kienzler, Sarah and Kreibich, Heidi and Kuhlicke, Christian and Kunz, Michael and Muehr, Bernhard and Mueller, Meike and Otto, Antje and Petrow, Theresia and Pisi, Sebastian and Schroeter, Kai}, title = {Review of the flood risk management system in Germany after the major flood in 2013}, series = {Ecology and society : a journal of integrative science for resilience and sustainability}, volume = {21}, journal = {Ecology and society : a journal of integrative science for resilience and sustainability}, publisher = {Resilience Alliance}, address = {Wolfville}, issn = {1708-3087}, doi = {10.5751/ES-08547-210251}, pages = {8612 -- 8614}, year = {2016}, abstract = {Widespread flooding in June 2013 caused damage costs of (sic)6 to 8 billion in Germany, and awoke many memories of the floods in August 2002, which resulted in total damage of (sic)11.6 billion and hence was the most expensive natural hazard event in Germany up to now. The event of 2002 does, however, also mark a reorientation toward an integrated flood risk management system in Germany. Therefore, the flood of 2013 offered the opportunity to review how the measures that politics, administration, and civil society have implemented since 2002 helped to cope with the flood and what still needs to be done to achieve effective and more integrated flood risk management. The review highlights considerable improvements on many levels, in particular (1) an increased consideration of flood hazards in spatial planning and urban development, (2) comprehensive property-level mitigation and preparedness measures, (3) more effective flood warnings and improved coordination of disaster response, and (4) a more targeted maintenance of flood defense systems. In 2013, this led to more effective flood management and to a reduction of damage. Nevertheless, important aspects remain unclear and need to be clarified. This particularly holds for balanced and coordinated strategies for reducing and overcoming the impacts of flooding in large catchments, cross-border and interdisciplinary cooperation, the role of the general public in the different phases of flood risk management, as well as a transparent risk transfer system. Recurring flood events reveal that flood risk management is a continuous task. Hence, risk drivers, such as climate change, land-use changes, economic developments, or demographic change and the resultant risks must be investigated at regular intervals, and risk reduction strategies and processes must be reassessed as well as adapted and implemented in a dialogue with all stakeholders.}, language = {en} }