@article{LorenzSpatzDorhoutetal.1996,
  author    = {Lorenz, Bernd and Spatz, J. P. and Dorhout, P. K. and Casey, R. and D'Adamo, R. and Hochheimer, H. D.},
  title     = {High pressure absorption and Raman study of the quasilinear compound CsCuS6},
  year      = {1996},
  language  = {en}
}
@article{LorenzOrgzallDorhoutetal.1996,
  author    = {Lorenz, Bernd and Orgzall, Ingo and Dorhout, P. K. and Casey, R. and D'Adamo, R. and Hochheimer, H. D.},
  title     = {High pressure optical and Raman investigations of the ternary compound Cs2MoS4},
  year      = {1996},
  language  = {en}
}
@article{LorenzOrgzallDorhoutetal.1996,
  author    = {Lorenz, Bernd and Orgzall, Ingo and Dorhout, P. K. and Raymond, C. C. and Hochheimer, H. D.},
  title     = {Pressure induced phonon softening and structural phase transitions in Cs2MoS4},
  year      = {1996},
  language  = {en}
}
@article{HochheimerMenonParthasarathyetal.1994,
  author    = {Hochheimer, H. D. and Menon, V. and Parthasarathy, R. and Martin, C. R. and Bechthold, Jeff and Hor, P.-H. and Lorenz, Bernd and Spatz, J. P.},
  title     = {High pressure study of the temperature dependence of the conductivity of template synthesized polyaniline and polypyrrole},
  year      = {1994},
  language  = {en}
}
@article{HochheimerMenonParthasarathyetal.1994,
  author    = {Hochheimer, H. D. and Menon, V. and Parthasarathy, R. and Martin, C. R. and Bechthold, Jeff and Hor, P.-H. and Lorenz, Bernd and Spatz, J. P.},
  title     = {High pressure conductivity of template synthesized polypyrrole},
  year      = {1994},
  language  = {en}
}
@article{OrgzallLorenzMikatetal.1997,
  author    = {Orgzall, Ingo and Lorenz, Bernd and Mikat, J{\"u}rgen E. R. and Dietel, Reinhard and Knochenhauer, Gerald and Schulz, Burkhard},
  title     = {Raman and IR spectroscopic investigation of aromatic 1,3,4-oxadiazole polymers and oligomers},
  year      = {1997},
  abstract  = {The molecular structure of poly(p-phenylene-1,3,4-oxadiazole) (POD) is investigated using i.r. and Raman spectroscopy. Both methods reveal characteristic differences for the a- and b-POD forms that are most obvious in the spectral region between 1500 and 1650 cm-1. The spectra for dimer and tetramer compounds already show the same features as found for longer chains. Based on molecular modelling calculations these differences are assigned to cis and trans conformations of the main chain segments. High pressure measurements show a linear shift of the Raman lines and support the result of the thermodynamic stability of the trans conformation.},
  language  = {en}
}
@article{LorenzOrgzallDorhoutetal.1997,
  author    = {Lorenz, Bernd and Orgzall, Ingo and Dorhout, P. K. and Raymond, C. C. and Brister, K. and Weishaupt, K. and D'Adamo, R. and Hochheimer, H. D.},
  title     = {High pressure X-ray diffraction, absorption, luminescence and Raman scattering study of Cs2MoS4},
  year      = {1997},
  language  = {en}
}
@article{LorenzPeunOrgzall1997,
  author    = {Lorenz, Bernd and Peun, T. and Orgzall, Ingo},
  title     = {Kinetic and thermodynamic investigation of cBN formation in the system BN-Mg3N2},
  year      = {1997},
  language  = {en}
}
@article{OrgzallLorenzMikatetal.1998,
  author    = {Orgzall, Ingo and Lorenz, Bernd and Mikat, J{\"u}rgen E. R. and Reck, G{\"u}nter and Knochenhauer, Gerald and Schulz, Burkhard},
  title     = {Phase transition in 1,3,4-oxadiazole crystals under high pressure},
  year      = {1998},
  language  = {en}
}
@article{LorenzSpatzHochheimeretal.1995,
  author    = {Lorenz, Bernd and Spatz, J. P. and Hochheimer, H. D. and Menon, V. and Parthasarathy, R. and Martin, C. R. and Bechthold, Jeff and Hor, P.-H.},
  title     = {High pressure conductivity study of template synthesized polypyrrole : observation of a crossover from three to one dimensional variable range hopping},
  year      = {1995},
  language  = {en}
}
@article{LorenzHochheimerTozeretal.1995,
  author    = {Lorenz, Bernd and Hochheimer, H. D. and Tozer, S. W. and Menon, V. and Parthasarathy, R. and Martin, C. R. and Hor, P.-H.},
  title     = {High pressure low temperature investigation of template synthesized conducting polymers},
  year      = {1995},
  language  = {en}
}
@article{LorenzMillerHochheimeretal.1995,
  author    = {Lorenz, Bernd and Miller, A. J. and Hochheimer, H. D. and H{\"o}nle, W. and Li, T. and Ruoff, A. L.},
  title     = {High pressure phase transition in tetramethylammonium tetra bromocuprate},
  year      = {1995},
  language  = {en}
}
@article{LorenzSpatzHochheimeretal.1994,
  author    = {Lorenz, Bernd and Spatz, J. P. and Hochheimer, H. D. and Menon, V. and Parthasarathy, R. and Martin, C. R. and Bechthold, Jeff and Hor, P.-H.},
  title     = {Dimensional crossover of the temperature dependence of the electrical conductivity of template synthesized polyaniline and polypyrrole},
  year      = {1994},
  language  = {en}
}
@article{LorenzTozerHochheimeretal.1994,
  author    = {Lorenz, Bernd and Tozer, S. W. and Hochheimer, H. D. and Menon, V. and Parthasarathy, R. and Martin, C. R.},
  title     = {Magnetoresistance of conducting polymers},
  year      = {1994},
  language  = {en}
}
@article{LorenzSpatzWeishauptetal.1994,
  author    = {Lorenz, Bernd and Spatz, J. P. and Weishaupt, K. and Hochheimer, H. D. and Menon, V. and Parthasarathy, R. and Martin, C. R. and Bechthold, Jeff and Hor, P.-H.},
  title     = {Observation of crossover from three to two dimensional variable range hopping in template synthesized polypyrrole and polyaniline},
  year      = {1994},
  language  = {en}
}
@article{LorenzMillerHochheimeretal.1994,
  author    = {Lorenz, Bernd and Miller, A. J. and Hochheimer, H. D. and H{\"o}nle, W.},
  title     = {The observation of a new high pressure phase transition in tetramethyl ammonium tetrabromocuprate},
  year      = {1994},
  language  = {en}
}
@article{OrgzallLorenz1994,
  author    = {Orgzall, Ingo and Lorenz, Bernd},
  title     = {Computer simulation of microstructures and geometric properties of a random system of penetrable disks : a model for compacted powders},
  year      = {1994},
  language  = {en}
}
@article{LorenzShenHolzapfel1994,
  author    = {Lorenz, Bernd and Shen, Yuen R. and Holzapfel, W. B.},
  title     = {Characterization of the new luminescence pressure sensor SrFCl:Sm2+},
  year      = {1994},
  language  = {en}
}
@article{LorenzOrgzall1994,
  author    = {Lorenz, Bernd and Orgzall, Ingo},
  title     = {Optical absorption studies of sulfur at pressure up to 20 Gpa},
  year      = {1994},
  language  = {en}
}
@article{OrgzallLorenz1994,
  author    = {Orgzall, Ingo and Lorenz, Bernd},
  title     = {Kinetics of photoinduced phase transitions in sulfur below 10 Gpa},
  year      = {1994},
  language  = {en}
}
@article{OrgzallLorenz1994,
  author    = {Orgzall, Ingo and Lorenz, Bernd},
  title     = {Structure and fractal properties in geological crystallization processes due to nucleation and growth},
  year      = {1994},
  language  = {en}
}
@article{LorenzOrgzall1995,
  author    = {Lorenz, Bernd and Orgzall, Ingo},
  title     = {Cluster shapes in the continuum description of percolating networks},
  year      = {1995},
  language  = {en}
}
@article{LorenzHochheimerHoenle1995,
  author    = {Lorenz, Bernd and Hochheimer, H. D. and H{\"o}nle, W.},
  title     = {The observation of a new high pressure phase transition in tetramethyl ammonium tetrabromocuprate},
  year      = {1995},
  language  = {en}
}
@article{OrgzallLorenz1995,
  author    = {Orgzall, Ingo and Lorenz, Bernd},
  title     = {On the formation of photoinduced high pressure phases in sulfur below},
  year      = {1995},
  language  = {en}
}
@article{MikatOrgzallLorenzetal.1999,
  author    = {Mikat, J{\"u}rgen E. R. and Orgzall, Ingo and Lorenz, Bernd and Sapp, S. and Martin, C. R. and Burris, J. L. and Hochheimer, H. D.},
  title     = {High-pressure low-temperature electrical properties of template-synthesied polypyrrole at low synthesis temperature: Dimensional crossover under pressure},
  year      = {1999},
  language  = {en}
}
@article{OrgzallLorenzMikatetal.1999,
  author    = {Orgzall, Ingo and Lorenz, Bernd and Mikat, J{\"u}rgen E. R. and Reck, G{\"u}nter and Knochenhauer, Gerald and Schulz, Burkhard},
  title     = {Phase transition in 1,3,4-oxadiazole crystals under high pressure},
  year      = {1999},
  abstract  = {Crystalline 2,5-di(4-nitrophenyl)-1,3,4-oxadiazole (DNO) has been investigated at pressures up to 5 GPa using Raman and optical spectroscopy as well as energy dispersive X-ray techniques. At ambient pressure DNO shows an orthorhombic unit cell (a = 0.5448 nm, b = 1.2758 nm, c = 1.9720 nm, density 1.513 g cm-3) with an appropriate space group Pbcn. From Raman spectroscopic investigations three phase transitions have been detected at 0.88, 1.28, and 2.2 GPa, respectively. These transitions have also been confirmed by absorption spectroscopy and X-ray measurements. Molecular modeling simulations have considerably contributed to the interpretation of the X-ray diffractograms. In general, the nearly flat structure of the oxadiazole molecule is preserved during the transitions. All subsequent structures are characterized by a stack-like arrangement of the DNO molecules. Only the mutual position of these molecular stacks changes due to the transformations so that this process may be described as a topotactical reaction. Phases II and III show a monoclinic symmetry with space group P21/c with cell parameters a = 1.990 nm, b = 0.500 nm, c = 1.240 nm, ß = 91.7°, density 1.681 g cm-3 (phase II, determined at 1. 1 GPa) and a = 1.890 nm, b = 0.510 nm, C = 1.242 nm, ß = 89.0°, density 1.733 g cm-3 (phase 111, determined at 2.0 GPa), respectively. The high-pressure phase IV stable at least up to 5 GPa shows again an orthorhombic structure with space group Pccn with corresponding cell parameters at 2.9 GPa: a = 0.465 nm, b = 1.920 nm, c = 1.230 nm and density 1.857 g cm-3 . For the first phase a blue pressure shift of the onset of absorption by about 0.032 eV GPa has been observed that may be explained by pressure influences on the electronic conjugation of the molecule. In the intermediate and high-pressure phases II-IV the onset of absorption shifts to increased wavelengths due to larger intermolecular interactions and enhanced excitation delocalization with decreasing intermolecular spacing.},
  language  = {en}
}
@inproceedings{JacqminOezdemirFellKurbanetal.2021,
  author    = {Jacqmin, Julien and {\"O}zdemir, Paker Doğu and Fell Kurban, Caroline and Tun{\c{c}} Pekkan, Zelha and Koskinen, Johanna and Suonp{\"a}{\"a}, Maija and Seng, Cheyvuth and Carlon, May Kristine Jonson and Gayed, John Maurice and Cross, Jeffrey S. and Langseth, Inger and Jacobsen, Dan Yngve and Haugsbakken, Halvdan and Bethge, Joseph and Serth, Sebastian and Staubitz, Thomas and Wuttke, Tobias and Nordemann, Oliver and Das, Partha-Pratim and Meinel, Christoph and Ponce, Eva and Srinath, Sindhu and Allegue, Laura and Perach, Shai and Alexandron, Giora and Corti, Paola and Baudo, Valeria and Turr{\´o}, Carlos and Moura Santos, Ana and Nilsson, Charlotta and Maldonado-Mahauad, Jorge and Valdiviezo, Javier and Carvallo, Juan Pablo and Samaniego-Erazo, Nicolay and Poce, Antonella and Re, Maria Rosaria and Valente, Mara and Karp Gershon, Sa'ar and Ruip{\´e}rez-Valiente, Jos{\´e} A. and Despujol, Ignacio and Busquets, Jaime and Kerr, John and Lorenz, Anja and Sch{\"o}n, Sandra and Ebner, Martin and Wittke, Andreas and Beirne, Elaine and Nic Giolla Mhich{\´i}l, Mair{\´e}ad and Brown, Mark and Mac Lochlainn, Conch{\´u}r and Topali, Paraskevi and Chounta, Irene-Angelica and Ortega-Arranz, Alejandro and Villagr{\´a}-Sobrino, Sara L. and Mart{\´i}nez-Mon{\´e}s, Alejandra and Blackwell, Virginia Katherine and Wiltrout, Mary Ellen and Rami Gaddem, Mohamed and Hern{\´a}ndez Reyes, C{\´e}sar Augusto and Nagahama, Toru and Buchem, Ilona and Okatan, Ebru and Khalil, Mohammad and Casiraghi, Daniela and Sancassani, Susanna and Brambilla, Federica and Mihaescu, Vlad and Andone, Diana and Vasiu, Radu and Şahin, Muhittin and Egloffstein, Marc and Bothe, Max and Rohloff, Tobias and Schenk, Nathanael and Schwerer, Florian and Ifenthaler, Dirk and Hense, Julia and Bernd, Mike},
  title     = {EMOOCs 2021},
  editor    = {Meinel, Christoph and Staubitz, Thomas and Schweiger, Stefanie and Friedl, Christian and Kiers, Janine and Ebner, Martin and Lorenz, Anja and Ubachs, George and Mongenet, Catherine and Ruip{\´e}rez-Valiente, Jos{\´e} A. and Cortes Mendez, Manoel},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-86956-512-5},
  doi       = {10.25932/publishup-51030},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-510300},
  pages     = {vii, 295},
  year      = {2021},
  abstract  = {From June 22 to June 24, 2021, Hasso Plattner Institute, Potsdam, hosted the seventh European MOOC Stakeholder Summit (EMOOCs 2021) together with the eighth ACM Learning@Scale Conference. Due to the COVID-19 situation, the conference was held fully online. The boost in digital education worldwide as a result of the pandemic was also one of the main topics of this year's EMOOCs. All institutions of learning have been forced to transform and redesign their educational methods, moving from traditional models to hybrid or completely online models at scale. The learnings, derived from practical experience and research, have been explored in EMOOCs 2021 in six tracks and additional workshops, covering various aspects of this field. In this publication, we present papers from the conference's Experience Track, the Policy Track, the Business Track, the International Track, and the Workshops.},
  language  = {en}
}
@article{DeekenReichertZechetal.2022,
  author    = {Deeken, Friederike and Reichert, Markus and Zech, Hilmar and Wenzel, Julia and Wedemeyer, Friederike and Aguilera, Alvaro and Aslan, Acelya and Bach, Patrick and Bahr, Nadja Samia and Ebrahimi, Claudia and Fischbach, Pascale Christine and Ganz, Marvin and Garbusow, Maria and Großkopf, Charlotte M. and Heigert, Marie and Hentschel, Angela and Karl, Damian and Pelz, Patricia and Pinger, Mathieu and Riemerschmid, Carlotta and Rosenthal, Annika and Steffen, Johannes and Strehle, Jens and Weiss,, Franziska and Wieder, Gesine and Wieland, Alfred and Zaiser, Judith and Zimmermann, Sina and Walter, Henrik and Lenz, Bernd and Deserno, Lorenz and Smolka, Michael N. and Liu, Shuyan and Ebner-Priemer, Ulrich Walter and Heinz, Andreas and Rapp, Michael A.},
  title     = {Patterns of Alcohol Consumption Among Individuals With Alcohol Use Disorder During the COVID-19 Pandemic and Lockdowns in Germany},
  series = {JAMA Network Open},
  volume    = {5},
  journal   = {JAMA Network Open},
  edition   = {8},
  publisher = {JAMA Network / American Medical Association},
  address   = {Chicago, Illinois, USA},
  issn      = {2574-3805},
  doi       = {10.1001/jamanetworkopen.2022.24641},
  pages     = {1 -- 11},
  year      = {2022},
  abstract  = {Importance Alcohol consumption (AC) leads to death and disability worldwide. Ongoing discussions on potential negative effects of the COVID-19 pandemic on AC need to be informed by real-world evidence. Objective To examine whether lockdown measures are associated with AC and consumption-related temporal and psychological within-person mechanisms. Design, Setting, and Participants This quantitative, intensive, longitudinal cohort study recruited 1743 participants from 3 sites from February 20, 2020, to February 28, 2021. Data were provided before and within the second lockdown of the COVID-19 pandemic in Germany: before lockdown (October 2 to November 1, 2020); light lockdown (November 2 to December 15, 2020); and hard lockdown (December 16, 2020, to February 28, 2021). Main Outcomes and Measures Daily ratings of AC (main outcome) captured during 3 lockdown phases (main variable) and temporal (weekends and holidays) and psychological (social isolation and drinking intention) correlates. Results Of the 1743 screened participants, 189 (119 [63.0\%] male; median [IQR] age, 37 [27.5-52.0] years) with at least 2 alcohol use disorder (AUD) criteria according to the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) yet without the need for medically supervised alcohol withdrawal were included. These individuals provided 14 694 smartphone ratings from October 2020 through February 2021. Multilevel modeling revealed significantly higher AC (grams of alcohol per day) on weekend days vs weekdays (β = 11.39; 95\% CI, 10.00-12.77; P < .001). Alcohol consumption was above the overall average on Christmas (β = 26.82; 95\% CI, 21.87-31.77; P < .001) and New Year's Eve (β = 66.88; 95\% CI, 59.22-74.54; P < .001). During the hard lockdown, perceived social isolation was significantly higher (β = 0.12; 95\% CI, 0.06-0.15; P < .001), but AC was significantly lower (β = -5.45; 95\% CI, -8.00 to -2.90; P = .001). Independent of lockdown, intention to drink less alcohol was associated with lower AC (β = -11.10; 95\% CI, -13.63 to -8.58; P < .001). Notably, differences in AC between weekend and weekdays decreased both during the hard lockdown (β = -6.14; 95\% CI, -9.96 to -2.31; P = .002) and in participants with severe AUD (β = -6.26; 95\% CI, -10.18 to -2.34; P = .002). Conclusions and Relevance This 5-month cohort study found no immediate negative associations of lockdown measures with overall AC. Rather, weekend-weekday and holiday AC patterns exceeded lockdown effects. Differences in AC between weekend days and weekdays evinced that weekend drinking cycles decreased as a function of AUD severity and lockdown measures, indicating a potential mechanism of losing and regaining control. This finding suggests that temporal patterns and drinking intention constitute promising targets for prevention and intervention, even in high-risk individuals.},
  language  = {en}
}
@misc{DeekenReichertZechetal.,
  author    = {Deeken, Friederike and Reichert, Markus and Zech, Hilmar and Wenzel, Julia and Wedemeyer, Friederike and Aguilera, Alvaro and Aslan, Acelya and Bach, Patrick and Bahr, Nadja Samia and Ebrahimi, Claudia and Fischbach, Pascale Christine and Ganz, Marvin and Garbusow, Maria and Großkopf, Charlotte M. and Heigert, Marie and Hentschel, Angela and Karl, Damian and Pelz, Patricia and Pinger, Mathieu and Riemerschmid, Carlotta and Rosenthal, Annika and Steffen, Johannes and Strehle, Jens and Weiss, Franziska and Wieder, Gesine and Wieland, Alfred and Zaiser, Judith and Zimmermann, Sina and Walter, Henrik and Lenz, Bernd and Deserno, Lorenz and Smolka, Michael N. and Liu, Shuyan and Ebner-Priemer, Ulrich Walter and Heinz, Andreas and Rapp, Michael A.},
  title     = {Patterns of Alcohol Consumption Among Individuals With Alcohol Use Disorder During the COVID-19 Pandemic and Lockdowns in Germany},
  series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  journal   = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  number    = {805},
  issn      = {1866-8364},
  doi       = {10.25932/publishup-57146},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-571460},
  pages     = {11},
  abstract  = {Importance Alcohol consumption (AC) leads to death and disability worldwide. Ongoing discussions on potential negative effects of the COVID-19 pandemic on AC need to be informed by real-world evidence. Objective To examine whether lockdown measures are associated with AC and consumption-related temporal and psychological within-person mechanisms. Design, Setting, and Participants This quantitative, intensive, longitudinal cohort study recruited 1743 participants from 3 sites from February 20, 2020, to February 28, 2021. Data were provided before and within the second lockdown of the COVID-19 pandemic in Germany: before lockdown (October 2 to November 1, 2020); light lockdown (November 2 to December 15, 2020); and hard lockdown (December 16, 2020, to February 28, 2021). Main Outcomes and Measures Daily ratings of AC (main outcome) captured during 3 lockdown phases (main variable) and temporal (weekends and holidays) and psychological (social isolation and drinking intention) correlates. Results Of the 1743 screened participants, 189 (119 [63.0\%] male; median [IQR] age, 37 [27.5-52.0] years) with at least 2 alcohol use disorder (AUD) criteria according to the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) yet without the need for medically supervised alcohol withdrawal were included. These individuals provided 14 694 smartphone ratings from October 2020 through February 2021. Multilevel modeling revealed significantly higher AC (grams of alcohol per day) on weekend days vs weekdays (β = 11.39; 95\% CI, 10.00-12.77; P < .001). Alcohol consumption was above the overall average on Christmas (β = 26.82; 95\% CI, 21.87-31.77; P < .001) and New Year's Eve (β = 66.88; 95\% CI, 59.22-74.54; P < .001). During the hard lockdown, perceived social isolation was significantly higher (β = 0.12; 95\% CI, 0.06-0.15; P < .001), but AC was significantly lower (β = -5.45; 95\% CI, -8.00 to -2.90; P = .001). Independent of lockdown, intention to drink less alcohol was associated with lower AC (β = -11.10; 95\% CI, -13.63 to -8.58; P < .001). Notably, differences in AC between weekend and weekdays decreased both during the hard lockdown (β = -6.14; 95\% CI, -9.96 to -2.31; P = .002) and in participants with severe AUD (β = -6.26; 95\% CI, -10.18 to -2.34; P = .002). Conclusions and Relevance This 5-month cohort study found no immediate negative associations of lockdown measures with overall AC. Rather, weekend-weekday and holiday AC patterns exceeded lockdown effects. Differences in AC between weekend days and weekdays evinced that weekend drinking cycles decreased as a function of AUD severity and lockdown measures, indicating a potential mechanism of losing and regaining control. This finding suggests that temporal patterns and drinking intention constitute promising targets for prevention and intervention, even in high-risk individuals.},
  language  = {en}
}
@misc{KaminskiSchlagenhaufRappetal.2018,
  author    = {Kaminski, Jakob A. and Schlagenhauf, Florian and Rapp, Michael A. and Awasthi, Swapnil and Ruggeri, Barbara and Deserno, Lorenz and Banaschewski, Tobias and Bokde, Arun L. W. and Bromberg, Uli and B{\"u}chel, Christian and Quinlan, Erin Burke and Desrivi{\`e}res, Sylvane and Flor, Herta and Frouin, Vincent and Garavan, Hugh and Gowland, Penny and Ittermann, Bernd and Martinot, Jean-Luc and Paill{\`e}re Martinot, Marie-Laure and Nees, Frauke and Papadopoulos Orfanos, Dimitri and Paus, Tom{\´a}š and Poustka, Luise and Smolka, Michael N. and Fr{\"o}hner, Juliane H. and Walter, Henrik and Whelan, Robert and Ripke, Stephan and Schumann, Gunter and Heinz, Andreas},
  title     = {Epigenetic variance in dopamine D2 receptor},
  series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  number    = {950},
  issn      = {1866-8372},
  doi       = {10.25932/publishup-42568},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-425687},
  pages     = {13},
  year      = {2018},
  abstract  = {Genetic and environmental factors both contribute to cognitive test performance. A substantial increase in average intelligence test results in the second half of the previous century within one generation is unlikely to be explained by genetic changes. One possible explanation for the strong malleability of cognitive performance measure is that environmental factors modify gene expression via epigenetic mechanisms. Epigenetic factors may help to understand the recent observations of an association between dopamine-dependent encoding of reward prediction errors and cognitive capacity, which was modulated by adverse life events. The possible manifestation of malleable biomarkers contributing to variance in cognitive test performance, and thus possibly contributing to the "missing heritability" between estimates from twin studies and variance explained by genetic markers, is still unclear. Here we show in 1475 healthy adolescents from the IMaging and GENetics (IMAGEN) sample that general IQ (gIQ) is associated with (1) polygenic scores for intelligence, (2) epigenetic modification of DRD2 gene, (3) gray matter density in striatum, and (4) functional striatal activation elicited by temporarily surprising reward-predicting cues. Comparing the relative importance for the prediction of gIQ in an overlapping subsample, our results demonstrate neurobiological correlates of the malleability of gIQ and point to equal importance of genetic variance, epigenetic modification of DRD2 receptor gene, as well as functional striatal activation, known to influence dopamine neurotransmission. Peripheral epigenetic markers are in need of confirmation in the central nervous system and should be tested in longitudinal settings specifically assessing individual and environmental factors that modify epigenetic structure.},
  language  = {en}
}
@article{KaminskiSchlagenhaufRappetal.2018,
  author    = {Kaminski, Jakob A. and Schlagenhauf, Florian and Rapp, Michael A. and Awasthi, Swapnil and Ruggeri, Barbara and Deserno, Lorenz and Banaschewski, Tobias and Bokde, Arun L. W. and Bromberg, Uli and B{\"u}chel, Christian and Quinlan, Erin Burke and Desrivieres, Sylvane and Flor, Herta and Frouin, Vincent and Garavan, Hugh and Gowland, Penny and Ittermann, Bernd and Martinot, Jean-Luc and Martinot, Marie-Laure Paillere and Nees, Frauke and Orfanos, Dimitri Papadopoulos and Paus, Tomas and Poustka, Luise and Smolka, Michael N. and Fr{\"o}hner, Juliane H. and Walter, Henrik and Whelan, Robert and Ripke, Stephan and Schumann, Gunter and Heinz, Andreas},
  title     = {Epigenetic variance in dopamine D2 receptor},
  series = {Translational Psychiatry},
  volume    = {8},
  journal   = {Translational Psychiatry},
  publisher = {Nature Publ. Group},
  address   = {New York},
  organization    = {IMAGEN Consortium},
  issn      = {2158-3188},
  doi       = {10.1038/s41398-018-0222-7},
  pages     = {11},
  year      = {2018},
  abstract  = {Genetic and environmental factors both contribute to cognitive test performance. A substantial increase in average intelligence test results in the second half of the previous century within one generation is unlikely to be explained by genetic changes. One possible explanation for the strong malleability of cognitive performance measure is that environmental factors modify gene expression via epigenetic mechanisms. Epigenetic factors may help to understand the recent observations of an association between dopamine-dependent encoding of reward prediction errors and cognitive capacity, which was modulated by adverse life events. The possible manifestation of malleable biomarkers contributing to variance in cognitive test performance, and thus possibly contributing to the "missing heritability" between estimates from twin studies and variance explained by genetic markers, is still unclear. Here we show in 1475 healthy adolescents from the IMaging and GENetics (IMAGEN) sample that general IQ (gIQ) is associated with (1) polygenic scores for intelligence, (2) epigenetic modification of DRD2 gene, (3) gray matter density in striatum, and (4) functional striatal activation elicited by temporarily surprising reward-predicting cues. Comparing the relative importance for the prediction of gIQ in an overlapping subsample, our results demonstrate neurobiological correlates of the malleability of gIQ and point to equal importance of genetic variance, epigenetic modification of DRD2 receptor gene, as well as functional striatal activation, known to influence dopamine neurotransmission. Peripheral epigenetic markers are in need of confirmation in the central nervous system and should be tested in longitudinal settings specifically assessing individual and environmental factors that modify epigenetic structure.},
  language  = {en}
}
@misc{KaminskiSchlagenhaufRappetal.2018,
  author    = {Kaminski, Jakob and Schlagenhauf, Florian and Rapp, Michael A. and Awasthi, Swapnil and Ruggeri, Barbara and Deserno, Lorenz and Laura, Daedelow and Banaschewski, Tobias and Bokde, Arun and Quinlan, Erin Burke and Buechel, Christian and Bromberg, Uli and Desrivieres, Sylvane and Flor, Herta and Frouin, Vincent and Garavan, Hugh and Gowland, Penny and Ittermann, Bernd and Martinot, Jean-Luc and Martinot, Marie-Laure Paillere and Nees, Frauke and Orfanos, Dimitri Papadopoulos and Paus, Tomas and Poustka, Luise and Smolka, Michael and Froehner, Juliane and Walter, Henrik and Whelan, Robert and Ripke, Stephan and Schumann, Gunter and Heinz, Andreas},
  title     = {Variance in Dopaminergic Markers},
  series = {Biological psychiatry : a journal of psychiatric neuroscience and therapeutics ; a publication of the Society of Biological Psychiatry},
  volume    = {83},
  journal   = {Biological psychiatry : a journal of psychiatric neuroscience and therapeutics ; a publication of the Society of Biological Psychiatry},
  number    = {9},
  publisher = {Elsevier},
  address   = {New York},
  organization    = {IMAGEN Consortium},
  issn      = {0006-3223},
  doi       = {10.1016/j.biopsych.2018.02.311},
  pages     = {S118 -- S118},
  year      = {2018},
  language  = {en}
}