@article{SchuchStubbsMeyeretal.2019, author = {Schuch, Felipe B. and Stubbs, Brendon and Meyer, Jacob and Heissel, Andreas and Zech, Philipp and Vancampfort, Davy and Rosenbaum, Simon and Deenik, Jeroen and Firth, Joseph and Ward, Philip B. and Carvalho, Andre F. and Hiles, Sarah A.}, title = {Physical activity protects from incident anxiety: A meta-analysis of prospective cohort studies}, series = {Depression and anxiety}, volume = {36}, journal = {Depression and anxiety}, number = {9}, publisher = {Wiley}, address = {Hoboken}, issn = {1091-4269}, doi = {10.1002/da.22915}, pages = {846 -- 858}, year = {2019}, abstract = {Background Prospective cohorts have suggested that physical activity (PA) can decrease the risk of incident anxiety. However, no meta-analysis has been conducted. Aims To examine the prospective relationship between PA and incident anxiety and explore potential moderators. Methods Searches were conducted on major databases from inception to October 10, 2018 for prospective studies (at least 1 year of follow-up) that calculated the odds ratio (OR) of incident anxiety in people with high PA against people with low PA. Methodological quality was assessed using the Newcastle-Ottawa Scale (NOS). A random-effects meta-analysis was conducted and heterogeneity was explored using subgroup and meta-regression analysis. Results Across 14 cohorts of 13 unique prospective studies (N = 75,831, median males = 50.1\%) followed for 357,424 person-years, people with high self-reported PA (versus low PA) were at reduced odds of developing anxiety (adjusted odds ratio [AOR] = 0.74; 95\% confidence level [95\% CI] = 0.62, 0.88; crude OR = 0.80; 95\% CI = 0.69, 0.92). High self-reported PA was protective against the emergence of agoraphobia (AOR = 0.42; 95\% CI = 0.18, 0.98) and posttraumatic stress disorder (AOR = 0.57; 95\% CI = 0.39, 0.85). The protective effects for anxiety were evident in Asia (AOR = 0.31; 95\% CI = 0.10, 0.96) and Europe (AOR = 0.82; 95\% CI = 0.69, 0.97); for children/adolescents (AOR = 0.52; 95\% CI = 0.29, 0.90) and adults (AOR = 0.81; 95\% CI = 0.69, 0.95). Results remained robust when adjusting for confounding factors. Overall study quality was moderate to high (mean NOS = 6.7 out of 9). Conclusion Evidence supports the notion that self-reported PA can confer protection against the emergence of anxiety regardless of demographic factors. In particular, higher PA levels protects from agoraphobia and posttraumatic disorder.}, language = {en} } @misc{HeisselZechRappetal.2019, author = {Heissel, Andreas and Zech, Philipp and Rapp, Michael A. and Schuch, Felipe B. and Lawrence, Jimmy B. and Kangas, Maria and Heinzel, Stephan}, title = {Effects of exercise on depression and anxiety in persons living with HIV: A meta-analysis}, series = {Journal of psychosomatic research}, volume = {126}, journal = {Journal of psychosomatic research}, publisher = {Elsevier}, address = {Oxford}, issn = {0022-3999}, doi = {10.1016/j.jpsychores.2019.109823}, pages = {12}, year = {2019}, abstract = {Objective: The purpose of this systematic review and meta-analysis was to examine the effects of exercise on depression and anxiety in people living with HIV (PLWH), and to evaluate, through subgroup analysis, the effects of exercise type, frequency, supervision by exercise professionals, study quality, and control group conditions on these outcomes. Method: A literature search was conducted through four electronic databases from inception to February 2019. Considered for inclusion were randomized controlled trials (RCTs) investigating exercise interventions and depression or anxiety as outcomes in people living with HIV (>= 18 years of age). Ten studies were included (n = 479 participants, 49.67\% females at baseline), and the standardized mean difference (SMD) and heterogeneity were calculated using random-effect models. An additional pre-post meta-analysis was also conducted. Results: A large effect in favor of exercise when compared to controls was found for depression (SMD = -0.84, 95\%CI = [-1.57, -0.11], p = 0.02) and anxiety (SMD = -1.23, 95\%CI = [-2.42, 0.04], p = -0.04). Subgroup analyses for depression revealed large effects on depression for aerobic exercise only (SMD = -0.96, 95\%CI = [-1.63, -0.30], p = 0.004), a frequency of >= 3 exercise sessions per week (SMD = -1.39, 95\%CI = [-2.24, -0.54], p < 0.001), professionally supervised exercise (SMD = -1.40, 95\%CI = [-2.46, -0.17], p = 0.03]), and high-quality studies (SMD = -1.31, 95\%CI = [-2.46, -0.17], p = 0.02). Conclusion: Exercise seems to decrease depressive symptoms and anxiety in PLWH, but other larger and high-quality studies are needed to verify these effects.}, language = {en} } @article{MuzahidFonsecaRobertsetal.2018, author = {Muzahid, S. and Fonseca, G. and Roberts, A. and Rosenwasser, B. and Richter, Philipp and Narayanan, A. and Churchill, C. and Charlton, J.}, title = {COS-Weak: probing the CGM using analogues of weak Mg II absorbers at z < 0.3}, series = {Monthly notices of the Royal Astronomical Society}, volume = {476}, journal = {Monthly notices of the Royal Astronomical Society}, number = {4}, publisher = {Oxford Univ. Press}, address = {Oxford}, issn = {0035-8711}, doi = {10.1093/mnras/sty529}, pages = {4965 -- 4986}, year = {2018}, abstract = {We present a sample of 34 weak metal line absorbers at z < 0.3 selected by the simultaneous >3σ detections of the Si iiλ1260 and C iiλ1334 absorption lines, with Wr(SiII)<0.2 {\AA} and Wr(CII)<0.3 {\AA}, in archival HST/COS spectra. Our sample increases the number of known low-z 'weak absorbers' by a factor of >5. The column densities of H i and low-ionization metal lines obtained from Voigt profile fitting are used to build simple photoionization models. The inferred densities and line-of-sight thicknesses of the absorbers are in the ranges of -3.3 < log nH/cm-3 < -2.4 and ∼1 pc-50 kpc (median ≈500 pc), respectively. Most importantly, 85 per cent (50 per cent) of these absorbers show a metallicity of [Si/H]>-1.0(0.0)⁠. The fraction of systems showing near-/supersolar metallicity in our sample is significantly higher than in the H i-selected sample of Wotta et al., and the galaxy-selected sample of Prochaska et al., of absorbers probing the circum-galactic medium at similar redshift. A search for galaxies has revealed a significant galaxy-overdensity around these weak absorbers compared to random positions with a median impact parameter of 166 kpc from the nearest galaxy. Moreover, we find the presence of multiple galaxies in ≈80 per cent of the cases, suggesting group environments. The observed dN/dz of 0.8 ± 0.2 indicates that such metal-enriched, compact, dense structures are ubiquitous in the haloes of low-z group galaxies. We suggest that these are transient structures that are related to galactic outflows and/or stripping of metal-rich gas from galaxies.}, language = {en} } @misc{RichterPaerelsKaastra2008, author = {Richter, Philipp and Paerels, Frits B. S. and Kaastra, Jelle S.}, title = {FUV and X-Ray absorption in the warm-hot intergalactic medium}, series = {Postprints der Universit{\"a}t Potsdam : Mathematisch Naturwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch Naturwissenschaftliche Reihe}, number = {864}, issn = {1866-8372}, doi = {10.25932/publishup-43422}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-434226}, pages = {25 -- 49}, year = {2008}, abstract = {The Warm-Hot Intergalactic Medium (WHIM) arises from shock-heated gas collapsing in large-scale filaments and probably harbours a substantial fraction of the baryons in the local Universe. Absorption-line measurements in the ultraviolet (UV) and in the X-ray band currently represent the best method to study the WHIM at low redshifts. We here describe the physical properties of the WHIM and the concepts behind WHIM absorption line measurements of Hi and high ions such as Ovi, Ovii, and Oviii in the far-ultraviolet and X-ray band. We review results of recent WHIM absorption line studies carried out with UV and X-ray satellites such as FUSE, HST, Chandra, and XMM-Newton and discuss their implications for our knowledge of the WHIM.}, language = {en} } @article{DautzenbergKoetzRotheretal.1994, author = {Dautzenberg, Herbert and Koetz, Joachim and Rother, G. and Philipp, B. and Rother, G.}, title = {Static light scattering of polyelectrolyte complex solutions}, year = {1994}, language = {en} } @article{DautzenbergJaegerKoetzetal.1994, author = {Dautzenberg, Herbert and Jaeger, Werner and Koetz, Joachim and Philipp, B. and Seidel, Ch. and Stscherbina, D.}, title = {Polyelectrolytes : formation, characterization and application}, publisher = {Hanser}, address = {M{\"u}nchen [u.a.]}, pages = {XIV, 343 S.}, year = {1994}, language = {en} } @article{WinkelBenBekhtiDarmstaedteretal.2011, author = {Winkel, B. and Ben Bekhti, Nadya and Darmstaedter, V. and Floeer, L. and Kerp, J. and Richter, Philipp}, title = {The high-velocity cloud complex Galactic center negative as seen by EBHIS and GASS I. Cloud catalog and global properties}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {533}, journal = {Astronomy and astrophysics : an international weekly journal}, number = {18}, publisher = {EDP Sciences}, address = {Les Ulis}, issn = {0004-6361}, doi = {10.1051/0004-6361/201117357}, pages = {13}, year = {2011}, abstract = {Using Milky Way data of the new Effelsberg-Bonn HI Survey (EBHIS) and the Galactic All-Sky Survey (GASS), we present a revised picture of the high-velocity cloud (HVC) complex Galactic center negative (GCN). Owing to the higher angular resolution of these surveys compared to previous studies (e.g., the Leiden Dwingeloo Survey), we resolve complex GCN into lots of individual tiny clumps, that mostly have relatively broad line widths of more than 15 km s(-1). We do not detect a diffuse extended counterpart, which is unusual for an HVC complex. In total 243 clumps were identified and parameterized which allows us to statistically analyze the data. Cold-line components (i.e.,Delta upsilon(fwhm) < 7.5 km s(-1)) are found in about 5\% only of the identified cloudlets. Our analysis reveals that complex GCN is likely built up of several subpopulations that do not share a common origin. Furthermore, complex GCN might be a prime example for warm-gas accretion onto the Milky Way, where neutral HI clouds are not stable against interaction with the Milky Way gas halo and become ionized prior to accretion.}, language = {en} } @article{SchildrothRettigZimmermannKalketal.2011, author = {Schildroth, Janice and Rettig-Zimmermann, Juliane and Kalk, Philipp and Steege, Andreas and Faehling, Michael and Sendeski, Mauricio and Paliege, Alexander and Lai, En Yin and Bachmann, Sebastian and Persson, Pontus B. and Hocher, Berthold and Patzak, Andreas}, title = {Endothelin type A and B receptors in the control of afferent and efferent arterioles in mice}, series = {Nephrology, dialysis, transplantation}, volume = {26}, journal = {Nephrology, dialysis, transplantation}, number = {3}, publisher = {Oxford Univ. Press}, address = {Oxford}, issn = {0931-0509}, doi = {10.1093/ndt/gfq534}, pages = {779 -- 789}, year = {2011}, abstract = {Background. Endothelin 1 contributes to renal blood flow control and pathogenesis of kidney diseases. The differential effects, however, of endothelin 1 (ET-1) on afferent (AA) and efferent arterioles (EA) remain to be established. Methods. We investigated endothelin type A and B receptor (ETA-R, ETB-R) functions in the control of AA and EA. Arterioles of ETB-R deficient, rescued mice [ETB (-/-)] and wild types [ETB(+/+)] were microperfused. Results. ET-1 constricted AA stronger than EA in ETB (-/-) and ETB(+/+) mice. Results in AA: ET-1 induced similar constrictions in ETB(-/-) and ETB(+/+) mice. BQ-123 (ETA-R antagonist) inhibited this response in both groups. ALA-ET-1 and IRL1620 (ETB-R agonists) had no effect on arteriolar diameter. L-NAME did neither affect basal diameters nor ET-1 responses. Results in EA: ET-1 constricted EA stronger in ETB(+/+) compared to ETB(-/-). BQ-123 inhibited the constriction completely only in ETB(-/-). ALA-ET-1 and IRL1620 constricted only arterioles of ETB(+/+) mice. L-NAME decreased basal diameter in ETB(+/+), but not in ETB(-/-) mice and increased the ET-1 response similarly in both groups. The L-NAME actions indicate a contribution of ETB-R in basal nitric oxide (NO) release in EA and suggest dilatory action of ETA-R in EA. Conclusions. ETA-R mediates vasoconstriction in AA and contributes to vasoconstriction in EA in this mouse model. ETB-R has no effect in AA but mediates basal NO release and constriction in EA. The stronger effect of ET-1 on AA supports observations of decreased glomerular filtration rate to ET-1 and indicates a potential contribution of ET-1 to the pathogenesis of kidney diseases.}, language = {en} } @article{WisotzkiBaconBrinchmannetal.2018, author = {Wisotzki, Lutz and Bacon, R. and Brinchmann, J. and Cantalupo, S. and Richter, Philipp and Schaye, J. and Schmidt, Kasper Borello and Urrutia, Tanya and Weilbacher, Peter Michael and Akhlaghi, M. and Bouche, N. and Contini, T. and Guiderdoni, B. and Herenz, E. C. and Inami, H. and Kerutt, Josephine Victoria and Leclercq, F. and Marino, R. A. and Maseda, M. and Monreal-Ibero, A. and Nanayakkara, T. and Richard, J. and Saust, R. and Steinmetz, Matthias and Wendt, Martin}, title = {Nearly all the sky is covered by Lyman-alpha emission around high-redshift galaxies}, series = {Nature : the international weekly journal of science}, volume = {562}, journal = {Nature : the international weekly journal of science}, number = {7726}, publisher = {Nature Publ. Group}, address = {London}, issn = {0028-0836}, doi = {10.1038/s41586-018-0564-6}, pages = {229 -- 232}, year = {2018}, abstract = {Galaxies are surrounded by large reservoirs of gas, mostly hydrogen, that are fed by inflows from the intergalactic medium and by outflows from galactic winds. Absorption-line measurements along the lines of sight to bright and rare background quasars indicate that this circumgalactic medium extends far beyond the starlight seen in galaxies, but very little is known about its spatial distribution. The Lyman-alpha transition of atomic hydrogen at a wavelength of 121.6 nanometres is an important tracer of warm (about 104 kelvin) gas in and around galaxies, especially at cosmological redshifts greater than about 1.6 at which the spectral line becomes observable from the ground. Tracing cosmic hydrogen through its Lyman-a emission has been a long-standing goal of observational astrophysics(1-3), but the extremely low surface brightness of the spatially extended emission is a formidable obstacle. A new window into circumgalactic environments was recently opened by the discovery of ubiquitous extended Lyman-alpha emission from hydrogen around high-redshift galaxies(4,5). Such measurements were previously limited to especially favourable systems(6-8) or to the use of massive statistical averaging(9,10) because of the faintness of this emission. Here we report observations of low-surface-brightness Lyman-alpha emission surrounding faint galaxies at redshifts between 3 and 6. We find that the projected sky coverage approaches 100 per cent. The corresponding rate of incidence (the mean number of Lyman-alpha emitters penetrated by any arbitrary line of sight) is well above unity and similar to the incidence rate of high-column-density absorbers frequently detected in the spectra of distant quasars(11-14). This similarity suggests that most circumgalactic atomic hydrogen at these redshifts has now been detected in emission.}, language = {en} } @article{CodecoWeisTrumbulletal.2021, author = {Code{\c{c}}o, Marta S. and Weis, Philipp and Trumbull, Robert B. and Van Hinsberg, Vincent and Pinto, Filipe and Lecumberri-Sanchez, Pilar and Schleicher, Anja Maria}, title = {The imprint of hydrothermal fluids on trace-element contents in white mica and tourmaline from the Panasqueira W-Sn-Cu deposit, Portugal}, series = {Mineralium Deposita}, volume = {56}, journal = {Mineralium Deposita}, number = {3}, publisher = {Springer}, address = {Berlin; Heidelberg}, issn = {1432-1866}, doi = {10.1007/s00126-020-00984-8}, pages = {481 -- 508}, year = {2021}, abstract = {White mica and tourmaline are the dominant hydrothermal alteration minerals at the world-class Panasqueira W-Sn-Cu deposit in Portugal. Thus, understanding the controls on their chemical composition helps to constrain ore formation processes at this deposit and determine their usefulness as pathfinder minerals for mineralization in general. We combine whole-rock geochemistry of altered and unaltered metasedimentary host rocks with in situ LA-ICP-MS measurements of tourmaline and white mica from the alteration halo. Principal component analysis (PCA) is used to better identify geochemical patterns and trends of hydrothermal alteration in the datasets. The hydrothermally altered metasediments are enriched in As, Sn, Cs, Li, W, F, Cu, Rb, Zn, Tl, and Pb relative to unaltered samples. In situ mineral analyses show that most of these elements preferentially partition into white mica over tourmaline (Li, Rb, Cs, Tl, W, and Sn), whereas Zn is enriched in tourmaline. White mica has distinct compositions in different settings within the deposit (greisen, vein selvages, wall rock alteration zone, late fault zone), indicating a compositional evolution with time. In contrast, tourmaline from different settings overlaps in composition, which is ascribed to a stronger dependence on host rock composition and also to the effects of chemical zoning and microinclusions affecting the LA-ICP-MS analyses. Hence, in this deposit, white mica is the better recorder of the fluid composition. The calculated trace-element contents of the Panasqueira mineralizing fluid based on the mica data and estimates of mica-fluid partition coefficients are in good agreement with previous fluid-inclusion analyses. A compilation of mica and tourmaline trace-element compositions from Panasqueira and other W-Sn deposits shows that white mica has good potential as a pathfinder mineral, with characteristically high Li, Cs, Rb, Sn, and W contents. The trace-element contents of hydrothermal tourmaline are more variable. Nevertheless, the compiled data suggest that high Sn and Li contents are distinctive for tourmaline from W-Sn deposits.}, language = {en} }