@article{WippertDeWittHubertsKlipkeretal.2015, author = {Wippert, Pia-Maria and De Witt Huberts, Jessie and Klipker, Kathrin and Gantz, Simone and Schiltenwolf, Marcus and Mayer, Frank}, title = {Development and content of the behavioral therapy module of the MiSpEx intervention. Randomized, controlled trial on chronic nonspecific low back pain}, series = {Der Schmerz : Organ der Deutschen Gesellschaft zum Studium des Schmerzes, der {\"O}sterreichischen Schmerzgesellschaft und der Deutschen Interdisziplin{\"a}ren Vereinigung f{\"u}r Schmerztherapie}, volume = {29}, journal = {Der Schmerz : Organ der Deutschen Gesellschaft zum Studium des Schmerzes, der {\"O}sterreichischen Schmerzgesellschaft und der Deutschen Interdisziplin{\"a}ren Vereinigung f{\"u}r Schmerztherapie}, number = {6}, publisher = {Springer}, address = {New York}, issn = {0932-433X}, doi = {10.1007/s00482-015-0044-y}, pages = {658 -- 663}, year = {2015}, abstract = {Back pain is a complex phenomenon that goes beyond a simple medical diagnosis. The aetiology and chronification of back pain can be best described as an interaction between biological, psychological, and social processes. However, to date, multimodal prevention and intervention programs for back pain that target all three aetiological factors have demonstrated limited effectiveness. This lack of supportive evidence for multimodal programmes in the treatment of back pain could be due to the fact that few programs are suitable for long-term and unsupervised use in everyday life. Moreover, in combining the elements from various therapies, little attention has been paid to the mechanisms underlying the synergistic effects of the separate components. In this contribution, we will describe the development of a new multimodal intervention for back pain that set out to address these limitations. To this end, the biological elements of neuromuscular adaptation is supplemented with cognitive behavioral and psychophysiological techniques in an intervention that can be followed at home as well as in clinics, and that is suitable for all grades of pain. The efficacy of this intervention will be tested in a multicentric randomized controlled longitudinal trial (n = 714) at five time points over a period of 6 months. Here we will describe the development and the content of this new intervention.}, language = {de} } @article{NiedererVogtWippertetal.2016, author = {Niederer, Daniel and Vogt, Lutz and Wippert, Pia-Maria and Puschmann, Anne-Katrin and Pfeifer, Ann-Christin and Schiltenwolf, Marcus and Banzer, Winfried and Mayer, Frank}, title = {Medicine in spine exercise (MiSpEx) for nonspecific low back pain patients: study protocol for a multicentre, single-blind randomized controlled trial}, series = {Trials}, volume = {17}, journal = {Trials}, publisher = {BioMed Central}, address = {London}, issn = {1745-6215}, doi = {10.1186/s13063-016-1645-1}, pages = {9}, year = {2016}, abstract = {Background: Arising from the relevance of sensorimotor training in the therapy of nonspecific low back pain patients and from the value of individualized therapy, the present trial aims to test the feasibility and efficacy of individualized sensorimotor training interventions in patients suffering from nonspecific low back pain. Methods and study design: A multicentre, single-blind two-armed randomized controlled trial to evaluate the effects of a 12-week (3 weeks supervised centre-based and 9 weeks home-based) individualized sensorimotor exercise program is performed. The control group stays inactive during this period. Outcomes are pain, and pain-associated function as well as motor function in adults with nonspecific low back pain. Each participant is scheduled to five measurement dates: baseline (M1), following centre-based training (M2), following home-based training (M3) and at two follow-up time points 6 months (M4) and 12 months (M5) after M1. All investigations and the assessment of the primary and secondary outcomes are performed in a standardized order: questionnaires - clinical examination biomechanics (motor function). Subsequent statistical procedures are executed after the examination of underlying assumptions for parametric or rather non-parametric testing. Discussion: The results and practical relevance of the study will be of clinical and practical relevance not only for researchers and policy makers but also for the general population suffering from nonspecific low back pain.}, language = {en} }