@article{GeisslerCharbonniereZiesseletal.2010, author = {Geißler, Daniel and Charbonni{\`e}re, Lo{\"i}c J. and Ziessel, Raymond F. and Butlin, Nathaniel G. and L{\"o}hmannsr{\"o}ben, Hans-Gerd and Hildebrandt, Niko}, title = {Quantum dot biosensors for ultrasensitive multiplexed diagnostics}, issn = {1433-7851}, doi = {10.1002/anie.200906399}, year = {2010}, abstract = {Time- and color-resolved detection of Foerster resonance energy transfer (FRET) from luminescent terbium complexes to different semiconductor quantum dots results in a fivefold multiplexed bioassay with sub-picomolar detection limits for all five bioanalytes (see picture). The detection of up to five biomarkers occurs with a sensitivity that is 40-240-fold higher than one of the best-established single-analyte reference assays.}, language = {en} }