@article{LiBenduhnQiaoetal.2019,
author = {Li, Tian-yi and Benduhn, Johannes and Qiao, Zhi and Liu, Yuan and Li, Yue and Shivhare, Rishi and Jaiser, Frank and Wang, Pei and Ma, Jie and Zeika, Olaf and Neher, Dieter and Mannsfeld, Stefan C. B. and Ma, Zaifei and Vandewal, Koen and Leo, Karl},
title = {Effect of H- and J-Aggregation on the Photophysical and Voltage Loss of Boron Dipyrromethene Small Molecules in Vacuum-Deposited Organic Solar Cells},
series = {The journal of physical chemistry letters},
volume = {10},
journal = {The journal of physical chemistry letters},
number = {11},
publisher = {American Chemical Society},
address = {Washington},
issn = {1948-7185},
doi = {10.1021/acs.jpclett.9b01222},
pages = {2684 -- 2691},
year = {2019},
abstract = {An understanding of the factors limiting the open-circuit voltage (V-oc) and related photon energy loss mechanisms is critical to increase the power conversion efficiency (PCE) of small-molecule organic solar cells (OSCs), especially those with near-infrared (NIR) absorbers. In this work, two NIR boron dipyrromethene (BODIPY) molecules are characterized for application in planar (PHJ) and bulk (BHJ) heterojunction OSCs. When two H atoms are substituted by F atoms on the peripheral phenyl rings of the molecules, the molecular aggregation type in the thin film changes from the H-type to J-type. For PHJ devices, the nonradiative voltage loss of 0.35 V in the J-aggregated BODIPY is lower than that of 0.49 V in the H-aggregated device. In BHJ devices with a nonradiative voltage loss of 0.35 V, a PCE of 5.5\% is achieved with an external quantum efficiency (EQE) maximum of 68\% at 700 nm.},
language = {en}
}
@article{UllbrichBenduhnJiaetal.2019,
author = {Ullbrich, Sascha and Benduhn, Johannes and Jia, Xiangkun and Nikolis, Vasileios C. and Tvingstedt, Kristofer and Piersimoni, Fortunato and Roland, Steffen and Liu, Yuan and Wu, Jinhan and Fischer, Axel and Neher, Dieter and Reineke, Sebastian and Spoltore, Donato and Vandewal, Koen},
title = {Emissive and charge-generating donor-acceptor interfaces for organic optoelectronics with low voltage losses},
series = {Nature materials},
volume = {18},
journal = {Nature materials},
number = {5},
publisher = {Nature Publ. Group},
address = {London},
issn = {1476-1122},
doi = {10.1038/s41563-019-0324-5},
pages = {459 -- 464},
year = {2019},
abstract = {Intermolecular charge-transfer states at the interface between electron donating (D) and accepting (A) materials are crucial for the operation of organic solar cells but can also be exploited for organic light-emitting diodes(1,2). Non-radiative charge-transfer state decay is dominant in state-of-the-art D-A-based organic solar cells and is responsible for large voltage losses and relatively low power-conversion efficiencies as well as electroluminescence external quantum yields in the 0.01-0.0001\% range(3,4). In contrast, the electroluminescence external quantum yield reaches up to 16\% in D-A-based organic light-emitting diodes(5-7). Here, we show that proper control of charge-transfer state properties allows simultaneous occurrence of a high photovoltaic and emission quantum yield within a single, visible-light-emitting D-A system. This leads to ultralow-emission turn-on voltages as well as significantly reduced voltage losses upon solar illumination. These results unify the description of the electro-optical properties of charge-transfer states in organic optoelectronic devices and foster the use of organic D-A blends in energy conversion applications involving visible and ultraviolet photons(8-11).},
language = {en}
}
@article{HofmanHaywardHeimetal.2019,
author = {Hofman, Maarten P. G. and Hayward, M. W. and Heim, M. and Marchand, P. and Rolandsen, C. M. and Mattisson, Jenny and Urbano, F. and Heurich, M. and Mysterud, A. and Melzheimer, J. and Morellet, N. and Voigt, Ulrich and Allen, B. L. and Gehr, Benedikt and Rouco Zufiaurre, Carlos and Ullmann, Wiebke and Holand, O. and Jorgensen, n H. and Steinheim, G. and Cagnacci, F. and Kroeschel, M. and Kaczensky, P. and Buuveibaatar, B. and Payne, J. C. and Palmegiani, I and Jerina, K. and Kjellander, P. and Johansson, O. and LaPoint, S. and Bayrakcismith, R. and Linnell, J. D. C. and Zaccaroni, M. and Jorge, M. L. S. and Oshima, J. E. F. and Songhurst, A. and Fischer, C. and Mc Bride, R. T. and Thompson, J. J. and Streif, S. and Sandfort, R. and Bonenfant, Christophe and Drouilly, M. and Klapproth, M. and Zinner, Dietmar and Yarnell, Richard and Stronza, A. and Wilmott, L. and Meisingset, E. and Thaker, Maria and Vanak, A. T. and Nicoloso, S. and Graeber, R. and Said, S. and Boudreau, M. R. and Devlin, A. and Hoogesteijn, R. and May-Junior, J. A. and Nifong, J. C. and Odden, J. and Quigley, H. B. and Tortato, F. and Parker, D. M. and Caso, A. and Perrine, J. and Tellaeche, C. and Zieba, F. and Zwijacz-Kozica, T. and Appel, C. L. and Axsom, I and Bean, W. T. and Cristescu, B. and Periquet, S. and Teichman, K. J. and Karpanty, S. and Licoppe, A. and Menges, V and Black, K. and Scheppers, Thomas L. and Schai-Braun, S. C. and Azevedo, F. C. and Lemos, F. G. and Payne, A. and Swanepoel, L. H. and Weckworth, B. and Berger, A. and Bertassoni, Alessandra and McCulloch, G. and Sustr, P. and Athreya, V and Bockmuhl, D. and Casaer, J. and Ekori, A. and Melovski, D. and Richard-Hansen, C. and van de Vyver, D. and Reyna-Hurtado, R. and Robardet, E. and Selva, N. and Sergiel, A. and Farhadinia, M. S. and Sunde, P. and Portas, R. and Ambarli, H{\"u}seyin and Berzins, R. and Kappeler, P. M. and Mann, G. K. and Pyritz, L. and Bissett, C. and Grant, T. and Steinmetz, R. and Swedell, Larissa and Welch, R. J. and Armenteras, D. and Bidder, O. R. and Gonzalez, T. M. and Rosenblatt, A. and Kachel, S. and Balkenhol, N.},
title = {Right on track?},
series = {PLoS one},
volume = {14},
journal = {PLoS one},
number = {5},
publisher = {PLoS},
address = {San Fransisco},
issn = {1932-6203},
doi = {10.1371/journal.pone.0216223},
pages = {26},
year = {2019},
abstract = {Satellite telemetry is an increasingly utilized technology in wildlife research, and current devices can track individual animal movements at unprecedented spatial and temporal resolutions. However, as we enter the golden age of satellite telemetry, we need an in-depth understanding of the main technological, species-specific and environmental factors that determine the success and failure of satellite tracking devices across species and habitats. Here, we assess the relative influence of such factors on the ability of satellite telemetry units to provide the expected amount and quality of data by analyzing data from over 3,000 devices deployed on 62 terrestrial species in 167 projects worldwide. We evaluate the success rate in obtaining GPS fixes as well as in transferring these fixes to the user and we evaluate failure rates. Average fix success and data transfer rates were high and were generally better predicted by species and unit characteristics, while environmental characteristics influenced the variability of performance. However, 48\% of the unit deployments ended prematurely, half of them due to technical failure. Nonetheless, this study shows that the performance of satellite telemetry applications has shown improvements over time, and based on our findings, we provide further recommendations for both users and manufacturers.},
language = {en}
}
@article{SturmWildermuthStolzetal.2019,
author = {Sturm, Heidrun and Wildermuth, Ronja and Stolz, Regina and Bertram, L. and Eschweiler, G. W. and Thomas, C. and Rapp, Michael A. and Joos, S.},
title = {Diverging awareness of postoperative delirium and cognitive dysfunction in German Health Care Providers},
series = {Clinical interventions in agins},
volume = {14},
journal = {Clinical interventions in agins},
publisher = {DOVE Medical Press},
address = {Albany},
issn = {1178-1998},
doi = {10.2147/CIA.S230800},
pages = {2125 -- 2135},
year = {2019},
abstract = {Purpose: Postoperative cognitive dysfunction (POCD) appears in up to 30\% of patients suffering from postoperative delirium (POD). Both are associated with higher mortality and postoperative complications, prolonged hospital stays, and increased costs. Multi-modal models with pre-admission risk reduction counselling, perioperative monitoring, and training of multidisciplinary patient care providers have been shown to decrease the prevalence of both. The aim of our study is to understand how far those measures are known and implemented in routine care and to detect potential gaps in the current practice regarding risk communication and information flow between involved caregivers for patients at risk for POD/POCD. Patients and Methods: As part of a multicenter study, seven semi-structured focus group (FG) discussions with nurses and physicians from tertiary care hospitals (surgery, anesthesiology, and orthopedics, n=31) and general practitioners (GPs) in private practice (n=7) were performed. Transcribed discussions were analyzed using qualitative content analysis. Results: POD is present above all in the daily work of nurses, whereas physicians do not perceive it as a relevant problem. Physicians report that no regular risk assessment or risk communication was performed prior to elective surgery. Information about POD often gets lost during hand-offs and is not regularly reported in discharge letters. Thus, persisting cognitive dysfunction is often missed. The importance of standardized documentation and continuous education concerning risks, screening, and treatment was emphasized. The often-suggested pre-OP medication adjustment was seen as less important; in contrast, avoiding withdrawal was regarded as far more important. Conclusion: Altogether, it seems that standards and available best practice concepts are rarely implemented. In contrast to physicians, nurses are highly aware of delirium and ask for standardized procedures and more responsibility. Therefore, raising awareness regarding risks, screening tools, and effective preventive measures for POD/POCD seems an urgent goal. Nurses should have a central role in coordination and care of POD to prevent the risk for POCD.},
language = {en}
}
@article{AbdallaAharonianBenkhalietal.2019,
author = {Abdalla, Hassan E. and Aharonian, Felix A. and Benkhali, F. Ait and Ang{\"u}ner, Ekrem Oǧuzhan and Arakawa, M. and Arcaro, C. and Armand, C. and Arrieta, M. and Backes, M. and Barnard, M. and Becherini, Y. and Tjus, J. Becker and Berge, D. and Bernhard, S. and Bernloehr, K. and Blackwell, R. and Bottcher, M. and Boisson, C. and Bolmont, J. and Bonnefoy, S. and Bordas, Pol and Bregeon, J. and Brun, F. and Brun, P. and Bryan, M. and Buechele, M. and Bulik, T. and Bylund, T. and Capasso, M. and Caroff, S. and Carosi, A. and Cerruti, M. and Chakraborty, N. and Chandra, S. and Chaves, R. C. G. and Chen, A. and Colafrancesco, S. and Condon, B. and Davids, I. D. and Deil, C. and Devin, J. and deWilt, P. and Dirson, L. and Djannati-Atai, A. and Dmytriiev, A. and Donath, A. and Doroshenko, V and Dyks, J. and Egberts, Kathrin and Emery, G. and Ernenwein, J-P and Eschbach, S. and Fegan, S. and Fiasson, A. and Fontaine, G. and Funk, S. and Fuessling, M. and Gabici, S. and Gallant, Y. A. and Gate, F. and Giavitto, G. and Glawion, D. and Glicenstein, J. F. and Gottschall, D. and Grondin, M-H and Hahn, J. and Haupt, M. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hinton, James Anthony and Hofmann, W. and Hoischen, Clemens and Holch, Tim Lukas and Holler, M. and Horns, D. and Huber, D. and Iwasaki, H. and Jacholkowska, A. and Jamrozy, M. and Jankowsky, D. and Jankowsky, F. and Jouvin, L. and Jung-Richardt, I and Kastendieck, M. A. and Katarzynski, K. and Katsuragawa, M. and Katz, U. and Kerszberg, D. and Khangulyan, D. and Khelifi, B. and King, J. and Klepser, S. and Kluzniak, W. and Komin, Nu and Kosack, K. and Krakau, S. and Kraus, M. and Kruger, P. P. and Lamanna, G. and Lau, J. and Lefaucheur, J. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J-P and Leser, Eva and Lohse, T. and Lorentz, M. and Lopez-Coto, R. and Lypova, I and Malyshev, D. and Marandon, V and Marcowith, Alexandre and Mariaud, C. and Marti-Devesa, G. and Marx, R. and Maurin, G. and Meintjes, P. J. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mohrmann, L. and Moulin, Emmanuel and Murach, T. and Nakashima, S. and de Naurois, M. and Ndiyavala, H. and Niederwanger, F. and Niemiec, J. and Oakes, L. and Odaka, H. and Ohm, S. and Ostrowski, M. and Oya, I and Padovani, M. and Panter, M. and Parsons, R. D. and Perennes, C. and Petrucci, P-O and Peyaud, B. and Piel, Q. and Pita, S. and Poireau, V and Noel, A. Priyana and Prokhorov, D. and Prokoph, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Rauth, R. and Reimer, A. and Reimer, O. and Renaud, M. and Rieger, F. and Rinchiuso, L. and Romoli, C. and Rowell, G. and Rudak, B. and Ruiz-Velasco, E. and Sahakian, V and Saito, S. and Sanchez, David M. and Santangelo, Andrea and Sasaki, M. and Schlickeiser, R. and Schussler, F. and Schulz, A. and Schwanke, U. and Schwemmer, S. and Seglar-Arroyo, M. and Senniappan, M. and Seyffert, A. S. and Shafi, N. and Shilon, I and Shiningayamwe, K. and Simoni, R. and Sinha, A. and Sol, H. and Spanier, F. and Specovius, A. and Spir-Jacob, M. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Steppa, Constantin Beverly and Takahashi, T. and Tavernet, J-P and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tibaldo, L. and Tiziani, D. and Tluczykont, M. and Trichard, C. and Tsirou, M. and Tsuji, N. and Tuffs, R. and Uchiyama, Y. and van der Walt, D. J. and van Eldik, C. and van Rensburg, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Vincent, P. and Vink, J. and Voisin, F. and Voelk, H. J. and Vuillaume, T. and Wadiasingh, Z. and Wagner, S. J. and Wagner, R. M. and White, R. and Wierzcholska, A. and Yang, R. and Zaborov, D. and Zacharias, M. and Zanin, R. and Zdziarski, A. A. and Zech, Alraune and Zefi, F. and Ziegler, A. and Zorn, J. and Zywucka, N.},
title = {The 2014TeV gamma-Ray Flare of Mrk 501 Seen with HESS},
series = {The astrophysical journal : an international review of spectroscopy and astronomical physics},
volume = {870},
journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics},
number = {2},
publisher = {IOP Publ. Ltd.},
address = {Bristol},
organization = {HESS Collaboration},
issn = {0004-637X},
doi = {10.3847/1538-4357/aaf1c4},
pages = {9},
year = {2019},
abstract = {The blazar Mrk 501 (z = 0.034) was observed at very-high-energy (VHE, E greater than or similar to 100 GeV) gamma-ray wavelengths during a bright flare on the night of 2014 June 23-24 (MJD 56832) with the H.E.S.S. phase-II array of Cherenkov telescopes. Data taken that night by H.E.S.S. at large zenith angle reveal an exceptional number of gamma-ray photons at multi-TeV energies, with rapid flux variability and an energy coverage extending significantly up to 20 TeV. This data set is used to constrain Lorentz invariance violation (LIV) using two independent channels: a temporal approach considers the possibility of an energy dependence in the arrival time of gamma-rays, whereas a spectral approach considers the possibility of modifications to the interaction of VHE gamma-rays with extragalactic background light (EBL) photons. The non-detection of energy-dependent time delays and the non-observation of deviations between the measured spectrum and that of a supposed power-law intrinsic spectrum with standard EBL attenuation are used independently to derive strong constraints on the energy scale of LIV (E-QG) in the subluminal scenario for linear and quadratic perturbations in the dispersion relation of photons. For the case of linear perturbations, the 95\% confidence level limits obtained are E-QG,E-1 > 3.6 x 10(17) GeV using the temporal approach and E-QG,E-1 > 2.6 x 10(19) GeV using the spectral approach. For the case of quadratic perturbations, the limits obtained are E-QG,E-2 > 8.5 x 10(10) GeV using the temporal approach and E-QG,E-2 > 7.8 x 10(11) GeV using the spectral approach.},
language = {en}
}
@article{AbdallaAdamAharonianetal.2019,
author = {Abdalla, Hassan E. and Adam, R. and Aharonian, Felix A. and Benkhali, F. Ait and Ang{\"u}ner, Ekrem Oǧuzhan and Arakawa, M. and Arcaro, C. and Armand, C. and Ashkar, H. and Backes, M. and Martins, V. Barbosa and Barnard, M. and Becherini, Y. and Berge, D. and Bernloehr, K. and Bissaldi, E. and Blackwell, R. and Boettcher, M. and Boisson, C. and Bolmont, J. and Bonnefoy, S. and Bregeon, J. and Breuhaus, M. and Brun, F. and Brun, P. and Bryan, M. and Buechele, M. and Bulik, T. and Bylund, T. and Capasso, M. and Caroff, S. and Carosi, A. and Casanova, Sabrina and Cerruti, M. and Chand, T. and Chandra, S. and Chen, A. and Colafrancesco, S. and Curylo, M. and Davids, I. D. and Deil, C. and Devin, J. and deWilt, P. and Dirson, L. and Djannati-Atai, A. and Dmytriiev, A. and Donath, A. and Doroshenko, V and Dyks, J. and Egberts, Kathrin and Emery, G. and Ernenwein, J-P and Eschbach, S. and Feijen, K. and Fegan, S. and Fiasson, A. and Fontaine, G. and Funk, S. and Fussling, Matthias and Gabici, S. and Gallant, Y. A. and Gate, F. and Giavitto, G. and Giunti, L. and Glawion, D. and Glicenstein, J. F. and Gottschall, D. and Grondin, M-H and Hahn, J. and Haupt, M. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hinton, J. A. and Hofmann, W. and Hoischen, Clemens and Holch, T. L. and Holler, M. and Horns, D. and Huber, D. and Iwasaki, H. and Jamrozy, M. and Jankowsky, D. and Jankowsky, F. and Jardin-Blicq, A. and Jung-Richardt, I and Kastendieck, M. A. and Katarzynski, K. and Katsuragawa, M. and Katz, U. and Khangulyan, D. and Khelifi, B. and King, J. and Klepser, S. and Kluzniak, W. and Komin, Nu and Kosack, K. and Kostunin, D. and Kreter, M. and Lamanna, G. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J-P and Leser, Eva and Levy, C. and Lohse, T. and Lypova, I and Mackey, J. and Majumdar, J. and Malyshev, D. and Marandon, V and Marcowith, Alexandre and Mares, A. and Mariaud, C. and Marti-Devesa, G. and Marx, R. and Maurin, G. and Meintjes, P. J. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mohrmann, L. and Moore, C. and Moulin, Emmanuel and Muller, J. and Murach, T. and Nakashima, S. and de Naurois, M. and Ndiyavala, H. and Niederwanger, F. and Niemiec, J. and Oakes, L. and Odaka, H. and Ohm, S. and Wilhelmi, E. de Ona and Ostrowski, M. and Oya, I and Panter, M. and Parsons, R. D. and Perennes, C. and Petrucci, P-O and Peyaud, B. and Piel, Q. and Pita, S. and Poireau, V and Noel, A. Priyana and Prokhorov, D. A. and Prokoph, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Rauth, R. and Reimer, A. and Reimer, O. and Remy, Q. and Renaud, M. and Rieger, F. and Rinchiuso, L. and Romoli, C. and Rowell, G. and Rudak, B. and Ruiz-Velasco, E. and Sahakian, V and Sailer, S. and Saito, S. and Sanchez, D. A. and Santangelo, Andrea and Sasaki, M. and Schlickeiser, R. and Schussler, F. and Schulz, A. and Schutte, H. M. and Schwanke, U. and Schwemmer, S. and Seglar-Arroyo, M. and Senniappan, M. and Seyffert, A. S. and Shafi, N. and Shiningayamwe, K. and Simoni, R. and Sinha, A. and Sol, H. and Specovius, A. and Spir-Jacob, M. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Steppa, Constantin Beverly and Takahashi, T. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tiziani, D. and Tluczykont, M. and Trichard, C. and Tsirou, M. and Tsuji, N. and Tuffs, R. and Uchiyama, Y. and van der Walt, D. J. and van Eldik, C. and van Rensburg, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Vincent, P. and Vink, J. and Voelk, H. J. and Vuillaume, T. and Wadiasingh, Z. and Wagner, S. J. and White, R. and Wierzcholska, A. and Yang, R. and Yoneda, H. and Zacharias, M. and Zanin, R. and Zdziarski, A. A. and Zech, Alraune and Ziegler, A. and Zorn, J. and Zywucka, N. and de Palma, F. and Axelsson, M. and Roberts, O. J.},
title = {A very-high-energy component deep in the gamma-ray burst afterglow},
series = {Nature : the international weekly journal of science},
volume = {575},
journal = {Nature : the international weekly journal of science},
number = {7783},
publisher = {Nature Publ. Group},
address = {London},
issn = {0028-0836},
doi = {10.1038/s41586-019-1743-9},
pages = {464 -- +},
year = {2019},
abstract = {Gamma-ray bursts (GRBs) are brief flashes of gamma-rays and are considered to be the most energetic explosive phenomena in the Universe(1). The emission from GRBs comprises a short (typically tens of seconds) and bright prompt emission, followed by a much longer afterglow phase. During the afterglow phase, the shocked outflow-produced by the interaction between the ejected matter and the circumburst medium-slows down, and a gradual decrease in brightness is observed(2). GRBs typically emit most of their energy via.-rays with energies in the kiloelectronvolt-to-megaelectronvolt range, but a few photons with energies of tens of gigaelectronvolts have been detected by space-based instruments(3). However, the origins of such high-energy (above one gigaelectronvolt) photons and the presence of very-high-energy (more than 100 gigaelectronvolts) emission have remained elusive(4). Here we report observations of very-high-energy emission in the bright GRB 180720B deep in the GRB afterglow-ten hours after the end of the prompt emission phase, when the X-ray flux had already decayed by four orders of magnitude. Two possible explanations exist for the observed radiation: inverse Compton emission and synchrotron emission of ultrarelativistic electrons. Our observations show that the energy fluxes in the X-ray and gamma-ray range and their photon indices remain comparable to each other throughout the afterglow. This discovery places distinct constraints on the GRB environment for both emission mechanisms, with the inverse Compton explanation alleviating the particle energy requirements for the emission observed at late times. The late timing of this detection has consequences for the future observations of GRBs at the highest energies.},
language = {en}
}
@article{PerkinsGanzertRojasJimenezetal.2019,
author = {Perkins, Anita K. and Ganzert, Lars and Rojas-Jimenez, Keilor and Fonvielle, Jeremy Andre and Hose, Grant C. and Grossart, Hans-Peter},
title = {Highly diverse fungal communities in carbon-rich aquifers of two contrasting lakes in Northeast Germany},
series = {Fungal ecology},
volume = {41},
journal = {Fungal ecology},
publisher = {Elsevier},
address = {Oxford},
issn = {1754-5048},
doi = {10.1016/j.funeco.2019.04.004},
pages = {116 -- 125},
year = {2019},
abstract = {Fungi are an important component of microbial communities and are well known for their ability to decompose refractory, highly polymeric organic matter. In soils and aquatic systems, fungi play an important role in carbon processing, however, their diversity, community structure and function as well as ecological role, particularly in groundwater, are poorly studied. The aim of this study was to examine the fungal community composition, diversity and function in groundwater from 16 boreholes located in the vicinity of two lakes in NE Germany that are characterized by contrasting trophic status. The analysis of 28S rRNA gene sequences amplified from the groundwater revealed high fungal diversity arid clear differences in community structure between the aquifers. Most sequences were assigned to Ascomycota and Basidiomycota, but members of Chytridiomycota, Cryptomycota, Zygomycota, Blastocladiomycota, Glomeromycota and Neocallimastigomycota were also detected. In addition, 27 species of fungi were successfully isolated from the groundwater samples and tested for their ability to decompose complex organic polymers - the predominant carbon source in the groundwater. Most isolates showed positive activities for at least one of the tested polymer types, with three strains, belonging to the genera Gibberella, Isaria and Cadophora, able to decompose all tested substrates. Our results highlight the high diversity of fungi in groundwater, and point to their important ecological role in breaking down highly polymeric organic matter in these isolated microbial habitats. (C) 2019 Elsevier Ltd and British Mycological Society. All rights reserved.},
language = {en}
}
@article{HegerBernardVerdierGessleretal.2019,
author = {Heger, Tina and Bernard-Verdier, Maud and Gessler, Arthur and Greenwood, Alex D. and Grossart, Hans-Peter and Hilker, Monika and Keinath, Silvia and Kowarik, Ingo and K{\"u}ffer, Christoph and Marquard, Elisabeth and Mueller, Johannes and Niemeier, Stephanie and Onandia, Gabriela and Petermann, Jana S. and Rillig, Matthias C. and Rodel, Mark-Oliver and Saul, Wolf-Christian and Schittko, Conrad and Tockner, Klement and Joshi, Jasmin Radha and Jeschke, Jonathan M.},
title = {Towards an Integrative, Eco-Evolutionary Understanding of Ecological Novelty: Studying and Communicating Interlinked Effects of Global Change},
series = {Bioscience},
volume = {69},
journal = {Bioscience},
number = {11},
publisher = {Oxford Univ. Press},
address = {Oxford},
issn = {0006-3568},
doi = {10.1093/biosci/biz095},
pages = {888 -- 899},
year = {2019},
abstract = {Global change has complex eco-evolutionary consequences for organisms and ecosystems, but related concepts (e.g., novel ecosystems) do not cover their full range. Here we propose an umbrella concept of "ecological novelty" comprising (1) a site-specific and (2) an organism-centered, eco-evolutionary perspective. Under this umbrella, complementary options for studying and communicating effects of global change on organisms, ecosystems, and landscapes can be included in a toolbox. This allows researchers to address ecological novelty from different perspectives, e.g., by defining it based on (a) categorical or continuous measures, (b) reference conditions related to sites or organisms, and (c) types of human activities. We suggest striving for a descriptive, non-normative usage of the term "ecological novelty" in science. Normative evaluations and decisions about conservation policies or management are important, but require additional societal processes and engagement with multiple stakeholders.},
language = {en}
}
@article{BurattiThomasRoussosetal.2019,
author = {Buratti, Bonnie J. and Thomas, P. C. and Roussos, Elias and Howett, Carly and Seiss, Martin and Hendrix, A. R. and Helfenstein, Paul and Brown, R. H. and Clark, R. N. and Denk, Tilmann and Filacchione, Gianrico and Hoffmann, Holger and Jones, Geraint H. and Khawaja, N. and Kollmann, Peter and Krupp, Norbert and Lunine, Jonathan and Momary, T. W. and Paranicas, Christopher and Postberg, Frank and Sachse, Manuel and Spahn, Frank and Spencer, John and Srama, Ralf and Albin, T. and Baines, K. H. and Ciarniello, Mauro and Economou, Thanasis and Hsu, Hsiang-Wen and Kempf, Sascha and Krimigis, Stamatios M. and Mitchell, Donald and Moragas-Klostermeyer, Georg and Nicholson, Philip D. and Porco, C. C. and Rosenberg, Heike and Simolka, Jonas and Soderblom, Laurence A.},
title = {Close Cassini flybys of Saturn's ring moons Pan, Daphnis, Atlas, Pandora, and Epimetheus},
series = {Science},
volume = {364},
journal = {Science},
number = {6445},
publisher = {American Assoc. for the Advancement of Science},
address = {Washington},
issn = {0036-8075},
doi = {10.1126/science.aat2349},
pages = {1053},
year = {2019},
abstract = {Saturn's main ring system is associated with a set of small moons that either are embedded within it or interact with the rings to alter their shape and composition. Five close flybys of the moons Pan, Daphnis, Atlas, Pandora, and Epimetheus were performed between December 2016 and April 2017 during the ring-grazing orbits of the Cassini mission. Data on the moons' morphology, structure, particle environment, and composition were returned, along with images in the ultraviolet and thermal infrared. We find that the optical properties of the moons' surfaces are determined by two competing processes: contamination by a red material formed in Saturn's main ring system and accretion of bright icy particles or water vapor from volcanic plumes originating on the moon Enceladus.},
language = {en}
}
@misc{SaidiZouhalRhibietal.2019,
author = {Saidi, Karim and Zouhal, Hassane and Rhibi, Fatma and Tijani, Jed M. and Boullosa, Daniel and Chebbi, Amel and Hackney, Anthony C. and Granacher, Urs and Bideau, Benoit and Ben Abderrahman, Abderraouf},
title = {Effects of a six-week period of congested match play on plasma volume variations, hematological parameters, training workload and physical fitness in elite soccer players},
series = {Postprints der Universit{\"a}t Potsdam Humanwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam Humanwissenschaftliche Reihe},
number = {572},
issn = {1866-8364},
doi = {10.25932/publishup-43716},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-437166},
pages = {17},
year = {2019},
abstract = {Objectives The aims of this study were to investigate the effects of a six-week in-season period of soccer training and games (congested period) on plasma volume variations (PV), hematological parameters, and physical fitness in elite players. In addition, we analyzed relationships between training load, hematological parameters and players' physical fitness. Methods Eighteen elite players were evaluated before (T1) and after (T2) a six-week in-season period interspersed with 10 soccer matches. At T1 and T2, players performed the Yo-Yo intermittent recovery test level 1 (YYIR1), the repeated shuttle sprint ability test (RSSA), the countermovement jump test (CMJ), and the squat jump test (SJ). In addition, PV and hematological parameters (erythrocytes [M/mm3], hematocrit [\%], hemoglobin [g/dl], mean corpuscular volume [fl], mean corpuscular hemoglobin content [pg], and mean hemoglobin concentration [\%]) were assessed. Daily ratings of perceived exertion (RPE) were monitored in order to quantify the internal training load. Results From T1 to T2, significant performance declines were found for the YYIR1 (p<0.001, effect size [ES] = 0.5), RSSA (p<0.01, ES = 0.6) and SJ tests (p< 0.046, ES = 0.7). However, no significant changes were found for the CMJ (p = 0.86, ES = 0.1). Post-exercise, RSSA blood lactate (p<0.012, ES = 0.2) and PV (p<0.01, ES = 0.7) increased significantly from T1 to T2. A significant decrease was found from T1 to T2 for the erythrocyte value (p<0.002, ES = 0.5) and the hemoglobin concentration (p<0.018, ES = 0.8). The hematocrit percentage rate was also significantly lower (p<0.001, ES = 0.6) at T2. The mean corpuscular volume, mean corpuscular hemoglobin content and the mean hemoglobin content values were not statistically different from T1 to T2. No significant relationships were detected between training load parameters and percentage changes of hematological parameters. However, a significant relationship was observed between training load and changes in RSSA performance (r = -0.60; p<0.003). Conclusions An intensive period of "congested match play" over 6 weeks significantly compromised players' physical fitness. These changes were not related to hematological parameters, even though significant alterations were detected for selected measures.},
language = {en}
}
@article{SaidiZouhalRhibietal.2019,
author = {Saidi, Karim and Zouhal, Hassane and Rhibi, Fatma and Tijani, Jed M. and Boullosa, Daniel and Chebbi, Amel and Hackney, Anthony C. and Granacher, Urs and Bideau, Benoit and Ben Abderrahman, Abderraouf},
title = {Effects of a six-week period of congested match play on plasma volume variations, hematological parameters, training workload and physical fitness in elite soccer players},
series = {PLOS ONE},
volume = {14},
journal = {PLOS ONE},
number = {7},
publisher = {Public Library of Science},
address = {San Francisco},
issn = {1932-6203},
doi = {10.1371/journal.pone.0219692},
pages = {17},
year = {2019},
abstract = {Objectives The aims of this study were to investigate the effects of a six-week in-season period of soccer training and games (congested period) on plasma volume variations (PV), hematological parameters, and physical fitness in elite players. In addition, we analyzed relationships between training load, hematological parameters and players' physical fitness. Methods Eighteen elite players were evaluated before (T1) and after (T2) a six-week in-season period interspersed with 10 soccer matches. At T1 and T2, players performed the Yo-Yo intermittent recovery test level 1 (YYIR1), the repeated shuttle sprint ability test (RSSA), the countermovement jump test (CMJ), and the squat jump test (SJ). In addition, PV and hematological parameters (erythrocytes [M/mm3], hematocrit [\%], hemoglobin [g/dl], mean corpuscular volume [fl], mean corpuscular hemoglobin content [pg], and mean hemoglobin concentration [\%]) were assessed. Daily ratings of perceived exertion (RPE) were monitored in order to quantify the internal training load. Results From T1 to T2, significant performance declines were found for the YYIR1 (p<0.001, effect size [ES] = 0.5), RSSA (p<0.01, ES = 0.6) and SJ tests (p< 0.046, ES = 0.7). However, no significant changes were found for the CMJ (p = 0.86, ES = 0.1). Post-exercise, RSSA blood lactate (p<0.012, ES = 0.2) and PV (p<0.01, ES = 0.7) increased significantly from T1 to T2. A significant decrease was found from T1 to T2 for the erythrocyte value (p<0.002, ES = 0.5) and the hemoglobin concentration (p<0.018, ES = 0.8). The hematocrit percentage rate was also significantly lower (p<0.001, ES = 0.6) at T2. The mean corpuscular volume, mean corpuscular hemoglobin content and the mean hemoglobin content values were not statistically different from T1 to T2. No significant relationships were detected between training load parameters and percentage changes of hematological parameters. However, a significant relationship was observed between training load and changes in RSSA performance (r = -0.60; p<0.003). Conclusions An intensive period of "congested match play" over 6 weeks significantly compromised players' physical fitness. These changes were not related to hematological parameters, even though significant alterations were detected for selected measures.},
language = {en}
}
@article{Schenck2020,
author = {Schenck, Marcia C.},
title = {Small Strangers at the School of Friendship: Memories of Mozambican School Students of The German Democratic Republic},
series = {German Historical Institute Washington Bulletin / Supplement},
journal = {German Historical Institute Washington Bulletin / Supplement},
number = {15},
publisher = {Max Weber Stiftung - Deutsche Geisteswissenschaftliche Institute im Ausland},
pages = {41 -- 59},
year = {2020},
language = {en}
}
@article{RyoJeschkeRilligetal.2020,
author = {Ryo, Masahiro and Jeschke, Jonathan M. and Rillig, Matthias C. and Heger, Tina},
title = {Machine learning with the hierarchy-of-hypotheses (HoH) approach discovers novel pattern in studies on biological invasions},
series = {Research synthesis methods},
volume = {11},
journal = {Research synthesis methods},
number = {1},
publisher = {Wiley},
address = {Hoboken},
issn = {1759-2879},
doi = {10.1002/jrsm.1363},
pages = {66 -- 73},
year = {2020},
abstract = {Research synthesis on simple yet general hypotheses and ideas is challenging in scientific disciplines studying highly context-dependent systems such as medical, social, and biological sciences. This study shows that machine learning, equation-free statistical modeling of artificial intelligence, is a promising synthesis tool for discovering novel patterns and the source of controversy in a general hypothesis. We apply a decision tree algorithm, assuming that evidence from various contexts can be adequately integrated in a hierarchically nested structure. As a case study, we analyzed 163 articles that studied a prominent hypothesis in invasion biology, the enemy release hypothesis. We explored if any of the nine attributes that classify each study can differentiate conclusions as classification problem. Results corroborated that machine learning can be useful for research synthesis, as the algorithm could detect patterns that had been already focused in previous narrative reviews. Compared with the previous synthesis study that assessed the same evidence collection based on experts' judgement, the algorithm has newly proposed that the studies focusing on Asian regions mostly supported the hypothesis, suggesting that more detailed investigations in these regions can enhance our understanding of the hypothesis. We suggest that machine learning algorithms can be a promising synthesis tool especially where studies (a) reformulate a general hypothesis from different perspectives, (b) use different methods or variables, or (c) report insufficient information for conducting meta-analyses.},
language = {en}
}
@article{CoesfeldKuesterKuechlyetal.2020,
author = {Coesfeld, Jacqueline and Kuester, Theres and Kuechly, Helga U. and Kyba, Christopher C. M.},
title = {Reducing variability and removing natural light from nighttime satellite imagery: A case study using the VIIRS DNB},
series = {Sensors},
volume = {20},
journal = {Sensors},
publisher = {MDPI},
address = {Basel},
pages = {13},
year = {2020},
abstract = {Temporal variation of natural light sources such as airglow limits the ability of night light sensors to detect changes in small sources of artificial light (such as villages). This study presents a method for correcting for this effect globally, using the satellite radiance detected from regions without artificial light emissions. We developed a routine to define an approximate grid of locations worldwide that do not have regular light emission. We apply this method with a 5 degree equally spaced global grid (total of 2016 individual locations), using data from the Visible Infrared Imaging Radiometer Suite (VIIRS) Day-Night Band (DNB). This code could easily be adapted for other future global sensors. The correction reduces the standard deviation of data in the Earth Observation Group monthly DNB composites by almost a factor of two. The code and datasets presented here are available under an open license by GFZ Data Services, and are implemented in the Radiance Light Trends web application.},
language = {en}
}
@article{AbdallaAdamAharonianetal.2020,
author = {Abdalla, Hassan E. and Adam, Remi and Aharonian, Felix A. and Benkhali, Faical Ait and Ang{\"u}ner, Ekrem Oǧuzhan and Arakawa, Masanori and Arcaro, C and Armand, Catherine and Armstrong, T. and Egberts, Kathrin},
title = {Very high energy γ-ray emission from two blazars of unknown redshift and upper limits on their distance},
series = {Monthly Notices of the Royal Astronomical Society},
volume = {494},
journal = {Monthly Notices of the Royal Astronomical Society},
number = {4},
publisher = {Wiley-Blackwell},
address = {Oxford},
pages = {13},
year = {2020},
abstract = {We report on the detection of very high energy (VHE; E > 100 GeV) gamma-ray emission from the BL Lac objects KUV 00311-1938 and PKS 1440-389 with the High Energy Stereoscopic System (H.E.S.S.). H.E.S.S. observations were accompanied or preceded by multiwavelength observations with Fermi/LAT, XRT and UVOT onboard the Swift satellite, and ATOM. Based on an extrapolation of the Fermi/LAT spectrum towards the VHE gamma-ray regime, we deduce a 95 per cent confidence level upper limit on the unknown redshift of KUV 00311-1938 of z < 0.98 and of PKS 1440-389 of z < 0.53. When combined with previous spectroscopy results, the redshift of KUV 00311-1938 is constrained to 0.51 <= z < 0.98 and of PKS 1440-389 to 0.14 (sic) z < 0.53.},
language = {en}
}
@misc{Schenck2020,
author = {Schenck, Marcia C.},
title = {Africa's forgotten refugee convention Africa is a Country},
series = {Histories of Refuge - Geschichten der Zuflucht},
journal = {Histories of Refuge - Geschichten der Zuflucht},
publisher = {Forum Transregionale Studien eV},
address = {Berlin},
year = {2020},
language = {en}
}
@misc{Schenck2020,
author = {Schenck, Marcia C.},
title = {History without borders},
series = {African Refugees Crossroads},
journal = {African Refugees Crossroads},
publisher = {H-Net: Humanities \& Social Sciences Online},
address = {East Lansing},
year = {2020},
language = {en}
}
@article{TesselaarBotzenHaeretal.2020,
author = {Tesselaar, Max and Botzen, W. J. Wouter and Haer, Toon and Hudson, Paul and Tiggeloven, Timothy and Aerts, Jeroen C. J. H.},
title = {Regional inequalities in flood insurance affordability and uptake under climate change},
series = {Sustainability},
volume = {12},
journal = {Sustainability},
number = {20},
publisher = {MDPI},
address = {Basel},
issn = {2071-1050},
doi = {10.3390/su12208734},
pages = {30},
year = {2020},
abstract = {Flood insurance coverage can enhance financial resilience of households to changing flood risk caused by climate change. However, income inequalities imply that not all households can afford flood insurance. The uptake of flood insurance in voluntary markets may decline when flood risk increases as a result of climate change. This increase in flood risk may cause substantially higher risk-based insurance premiums, reduce the willingness to purchase flood insurance, and worsen problems with the unaffordability of coverage for low-income households. A socio-economic tipping-point can occur when the functioning of a formal flood insurance system is hampered by diminishing demand for coverage. In this study, we examine whether such a tipping-point can occur in Europe for current flood insurance systems under different trends in future flood risk caused by climate and socio-economic change. This analysis gives insights into regional inequalities concerning the ability to continue to use flood insurance as an instrument to adapt to changing flood risk. For this study, we adapt the "Dynamic Integrated Flood and Insurance" (DIFI) model by integrating new flood risk simulations in the model that enable examining impacts from various scenarios of climate and socio-economic change on flood insurance premiums and consumer demand. Our results show rising unaffordability and declining demand for flood insurance across scenarios towards 2080. Under a high climate change scenario, simulations show the occurrence of a socio-economic tipping-point in several regions, where insurance uptake almost disappears. A tipping-point and related inequalities in the ability to use flood insurance as an adaptation instrument can be mitigated by introducing reforms of flood insurance arrangements.},
language = {en}
}
@article{LiuGouldKratzetal.2020,
author = {Liu, Yue and Gould, Oliver E. C. and Kratz, Karl and Lendlein, Andreas},
title = {Shape-memory actuation of individual micro-/nanofibers},
series = {MRS Advances},
volume = {5},
journal = {MRS Advances},
number = {46-47},
publisher = {Cambridge Univ. Press},
address = {New York},
issn = {2059-8521},
doi = {10.1557/adv.2020.276},
pages = {2391 -- 2399},
year = {2020},
abstract = {Advances in the fabrication and characterization of polymeric nanomaterials has greatly advanced the miniaturization of soft actuators, creating materials capable of replicating the functional physical behavior previously limited to the macroscale. Here, we demonstrate how a reversible shape-memory polymer actuation can be generated in a single micro/nano object, where the shape change during actuation of an individual fiber can be dictated by programming using an AFM-based method. Electrospinning was used to prepare poly(epsilon-caprolactone) micro-/nanofibers, which were fixed and crosslinked on a structured silicon wafer. The programming as well as the observation of recovery and reversible displacement of the fiber were performed by vertical three point bending, using an AFM testing platform introduced here. A plateau tip was utilized to improve the stability of the fiber contact and working distance, enabling larger deformations and greater rbSMPA performance. Values for the reversible elongation of epsilon(rev)= 3.4 +/- 0.1\% and 10.5 +/- 0.1\% were obtained for a single micro (d = 1.0 +/- 0.2 mu m) and nanofiber (d = 300 +/- 100 nm) in cyclic testing between the temperatures 10 and 60 degrees C. The reversible actuation of the nanofiber was successfully characterized for 10 cycles. The demonstration and characterization of individual shape-memory nano and microfiber actuators represents an important step in the creation of miniaturized robotic devices capable of performing complex physical functions at the length scale of cells and structural component of the extracellular matrix.},
language = {en}
}
@incollection{Schenck2020,
author = {Schenck, Marcia C.},
title = {Wandergesellen des Kalten Krieges},
series = {F{\"u}r Respekt und Anerkennung: Die mosambikanischen Vertragsarbeiter und das schwierige Erbe aus der DDR},
booktitle = {F{\"u}r Respekt und Anerkennung: Die mosambikanischen Vertragsarbeiter und das schwierige Erbe aus der DDR},
publisher = {Mitteldeutscher Verlag},
address = {Halle},
isbn = {978-3-96311-314-7},
pages = {103 -- 114},
year = {2020},
abstract = {Der Umgang mit einem schwierigen Erbe 2019 befasste sich die internationale Tagung »Respekt und Anerkennung« mit der Entwicklungszusammenarbeit Mosambik-Deutschland unter dem Schwerpunktthema Vertragsarbeit. Anlass war der 40. Jahrestag des 1979 geschlossenen Staatsvertrages der VR Mosambik mit der DDR. Der nun erscheinende Tagungsband enth{\"a}lt u. a. Beitr{\"a}ge zu den Themen »Die Lebenswege der Sch{\"u}lerInnen der Schule der Freundschaft in Staßfurt«, »DDR-ExpertInnen in Mosambik«, »Wie aus Vertragsarbeitern Madgermanes wurden« und »Auf dem Weg zu Respekt und Anerkennung: Sind wir f{\"u}r die Vers{\"o}hnung?«. Ein Dokumentenanhang erg{\"a}nzt den Band. Mit Beitr{\"a}gen von Katrin Baar, Ant{\´o}nio Daniel, Hans-Joachim D{\"o}ring, Ant{\´o}nio Frangoulis, Rainer Grajek, Adelino Massuvira Jo{\~a}o, L{\´a}zaro Magalh{\~a}es, Dinis Matsolo, Francisca Raposo, Marcia C. Schenck, Ralf Straßburg, Mathias Tullner und Cesare Zucconi.},
language = {de}
}
@article{MatthiasRisslingPieperetal.2020,
author = {Matthias, Katja and Rissling, Olesja and Pieper, Dawid Aleksander and Morche, Johannes and Nocon, Marc and Jacobs, Anja and Wegewitz, Uta Elke and Schirm, Jaqueline and Lorenz, Robert C.},
title = {The methodological quality of systematic reviews on the treatment of adult major depression needs improvement according to AMSTAR 2},
series = {Heliyon},
volume = {6},
journal = {Heliyon},
number = {9},
publisher = {Elsevier},
address = {London [u.a.]},
issn = {2405-8440},
doi = {10.1016/j.heliyon.2020.e04776},
pages = {7},
year = {2020},
abstract = {Background: Several standards have been developed to assess methodological quality of systematic reviews (SR). One widely used tool is the AMSTAR. A recent update -AMSTAR 2 -is a 16 item evaluation tool that enables a detailed assessment of SR that include randomised (RCT) or non-randomised studies (NRS) of healthcare interventions. Methods: A cross-sectional study of SR on pharmacological or psychological interventions in major depression in adults was conducted. SR published during 2012-2017 were sampled from MEDLINE, EMBASE and the Cochrane Database of SR. Methodological quality was assessed using AMSTAR 2. Potential predictive factors associated with quality were examined. Results: In rating overall confidence in the results of 60 SR four reviews were rated "high", two were "moderate", one was "low" and 53 were "critically low". The mean AMSTAR 2 percentage score was 45.3\% (standard deviation 22.6\%) in a wide range from 7.1\% to 93.8\%. Predictors of higher quality were: type of review (higher quality in Cochrane Reviews), SR including only randomized trials and higher journal impact factor. Limitations: AMSTAR 2 is not intended to be used for the generation of a percentage score. Conclusions: According to AMSTAR 2 the overall methodological quality of SR on the treatment of adult major depression needs improvement. Although there is a high need for summarized information in the field of mental health, this work demonstrates the need to critically assess SR before using their findings. Better adherence to established reporting guidelines for SR is needed.},
language = {en}
}
@article{Schenck2020,
author = {Schenck, Marcia C.},
title = {Small Strangers at the School of Friendship},
series = {German Historical Institute Bulletin: German Historical Institute Washington Bulletin},
volume = {2020},
journal = {German Historical Institute Bulletin: German Historical Institute Washington Bulletin},
number = {15: Histories of Migrant Knowledge: Transatlantic and Global Perspectives},
publisher = {German Historical Institute},
address = {Washington},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-494614},
pages = {41 -- 59},
year = {2020},
abstract = {"Why," Francisca Isidro wonders, "did we have to leave our families and move so far away, only to come back as cooks, waitresses, sales assistants, and the like?" And she recalls: "We came back from our time in East Germany with professions that were not held in particu-larly high regard in Mozambique. Nobody understood why we didn't return as engineers, doctors and teachers. 'A waitress?,' they would wonder. 'Why, they could have become a waitress in Mozambique. Nobody needs to spend so many years in school for that.'"2And with that, Ms. Isidro puts her fi nger right on a misapprehension at the heart of an ambitious state-led education migration program that saw 900 Mozambican children attend the School of Friendship (Schule der Freundschaft , SdF) in Staßfurt in the district of Magdeburg, in what today is Saxony-Anhalt, in the German Democratic Republic (GDR, or East Germany) from 1982 to 1988.3 Ms. Isidro returned to Mozambique as a trained salesperson for clothing, a profession she neither chose nor ever worked in again subsequently. Like her, these 900 children had to navigate the diverging values that particular environments bestowed upon knowledge. What they learned was interpreted diff erently in their home communities, at the SdF, and in their German host families},
language = {en}
}
@misc{CoesfeldKuesterKuechlyetal.2020,
author = {Coesfeld, Jacqueline and Kuester, Theres and Kuechly, Helga U. and Kyba, Christopher C. M.},
title = {Reducing variability and removing natural light from nighttime satellite imagery: A case study using the VIIRS DNB},
series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
number = {11},
issn = {1866-8372},
doi = {10.25932/publishup-52439},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-524397},
pages = {15},
year = {2020},
abstract = {Temporal variation of natural light sources such as airglow limits the ability of night light sensors to detect changes in small sources of artificial light (such as villages). This study presents a method for correcting for this effect globally, using the satellite radiance detected from regions without artificial light emissions. We developed a routine to define an approximate grid of locations worldwide that do not have regular light emission. We apply this method with a 5 degree equally spaced global grid (total of 2016 individual locations), using data from the Visible Infrared Imaging Radiometer Suite (VIIRS) Day-Night Band (DNB). This code could easily be adapted for other future global sensors. The correction reduces the standard deviation of data in the Earth Observation Group monthly DNB composites by almost a factor of two. The code and datasets presented here are available under an open license by GFZ Data Services, and are implemented in the Radiance Light Trends web application.},
language = {en}
}
@misc{RyoJeschkeRilligetal.2020,
author = {Ryo, Masahiro and Jeschke, Jonathan M. and Rillig, Matthias C. and Heger, Tina},
title = {Machine learning with the hierarchy-of-hypotheses (HoH) approach discovers novel pattern in studies on biological invasions},
series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
number = {1171},
issn = {1866-8372},
doi = {10.25932/publishup-51764},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-517643},
pages = {66 -- 73},
year = {2020},
abstract = {Research synthesis on simple yet general hypotheses and ideas is challenging in scientific disciplines studying highly context-dependent systems such as medical, social, and biological sciences. This study shows that machine learning, equation-free statistical modeling of artificial intelligence, is a promising synthesis tool for discovering novel patterns and the source of controversy in a general hypothesis. We apply a decision tree algorithm, assuming that evidence from various contexts can be adequately integrated in a hierarchically nested structure. As a case study, we analyzed 163 articles that studied a prominent hypothesis in invasion biology, the enemy release hypothesis. We explored if any of the nine attributes that classify each study can differentiate conclusions as classification problem. Results corroborated that machine learning can be useful for research synthesis, as the algorithm could detect patterns that had been already focused in previous narrative reviews. Compared with the previous synthesis study that assessed the same evidence collection based on experts' judgement, the algorithm has newly proposed that the studies focusing on Asian regions mostly supported the hypothesis, suggesting that more detailed investigations in these regions can enhance our understanding of the hypothesis. We suggest that machine learning algorithms can be a promising synthesis tool especially where studies (a) reformulate a general hypothesis from different perspectives, (b) use different methods or variables, or (c) report insufficient information for conducting meta-analyses.},
language = {en}
}
@misc{AbdallaAdamAharonianetal.2020,
author = {Abdalla, Hassan E. and Adam, Remi and Aharonian, Felix A. and Benkhali, Faical Ait and Ang{\"u}ner, Ekrem Oǧuzhan and Arakawa, Masanori and Arcaro, C and Armand, Catherine and Armstrong, T. and Egberts, Kathrin},
title = {Very high energy γ-ray emission from two blazars of unknown redshift and upper limits on their distance},
series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
number = {4},
issn = {1866-8372},
doi = {10.25932/publishup-52600},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-526000},
pages = {15},
year = {2020},
abstract = {We report on the detection of very high energy (VHE; E > 100 GeV) gamma-ray emission from the BL Lac objects KUV 00311-1938 and PKS 1440-389 with the High Energy Stereoscopic System (H.E.S.S.). H.E.S.S. observations were accompanied or preceded by multiwavelength observations with Fermi/LAT, XRT and UVOT onboard the Swift satellite, and ATOM. Based on an extrapolation of the Fermi/LAT spectrum towards the VHE gamma-ray regime, we deduce a 95 per cent confidence level upper limit on the unknown redshift of KUV 00311-1938 of z < 0.98 and of PKS 1440-389 of z < 0.53. When combined with previous spectroscopy results, the redshift of KUV 00311-1938 is constrained to 0.51 <= z < 0.98 and of PKS 1440-389 to 0.14 (sic) z < 0.53.},
language = {en}
}
@article{DennisBallesterosRobinetal.2020,
author = {Dennis, Alice B. and Ballesteros, Gabriel I. and Robin, St{\´e}phanie and Schrader, Lukas and Bast, Jens and Bergh{\"o}fer, Jan and Beukeboom, Leo W. and Belghazi, Maya and Bretaudeau, Anthony and Buellesbach, Jan and Cash, Elizabeth and Colinet, Dominique and Dumas, Zo{\´e} and Errbii, Mohammed and Falabella, Patrizia and Gatti, Jean-Luc and Geuverink, Elzemiek and Gibson, Joshua D. and Hertaeg, Corinne and Hartmann, Stefanie and Jacquin-Joly, Emmanuelle and Lammers, Mark and Lavandero, Blas I. and Lindenbaum, Ina and Massardier-Galata, Lauriane and Meslin, Camille and Montagn{\´e}, Nicolas and Pak, Nina and Poiri{\´e}, Maryl{\`e}ne and Salvia, Rosanna and Smith, Chris R. and Tagu, Denis and Tares, Sophie and Vogel, Heiko and Schwander, Tanja and Simon, Jean-Christophe and Figueroa, Christian C. and Vorburger, Christoph and Legeai, Fabrice and Gadau, J{\"u}rgen},
title = {Functional insights from the GC-poor genomes of two aphid parasitoids, Aphidius ervi and Lysiphlebus fabarum},
series = {BMC Genomics},
volume = {21},
journal = {BMC Genomics},
publisher = {BioMed Central},
address = {London},
issn = {1471-2164},
doi = {10.1186/s12864-020-6764-0},
pages = {27},
year = {2020},
abstract = {Background Parasitoid wasps have fascinating life cycles and play an important role in trophic networks, yet little is known about their genome content and function. Parasitoids that infect aphids are an important group with the potential for biological control. Their success depends on adapting to develop inside aphids and overcoming both host aphid defenses and their protective endosymbionts. Results We present the de novo genome assemblies, detailed annotation, and comparative analysis of two closely related parasitoid wasps that target pest aphids: Aphidius ervi and Lysiphlebus fabarum (Hymenoptera: Braconidae: Aphidiinae). The genomes are small (139 and 141 Mbp) and the most AT-rich reported thus far for any arthropod (GC content: 25.8 and 23.8\%). This nucleotide bias is accompanied by skewed codon usage and is stronger in genes with adult-biased expression. AT-richness may be the consequence of reduced genome size, a near absence of DNA methylation, and energy efficiency. We identify missing desaturase genes, whose absence may underlie mimicry in the cuticular hydrocarbon profile of L. fabarum. We highlight key gene groups including those underlying venom composition, chemosensory perception, and sex determination, as well as potential losses in immune pathway genes. Conclusions These findings are of fundamental interest for insect evolution and biological control applications. They provide a strong foundation for further functional studies into coevolution between parasitoids and their hosts. Both genomes are available at https://bipaa.genouest.org.},
language = {en}
}
@misc{DennisBallesterosRobinetal.2020,
author = {Dennis, Alice B. and Ballesteros, Gabriel I. and Robin, St{\´e}phanie and Schrader, Lukas and Bast, Jens and Bergh{\"o}fer, Jan and Beukeboom, Leo W. and Belghazi, Maya and Bretaudeau, Anthony and Buellesbach, Jan and Cash, Elizabeth and Colinet, Dominique and Dumas, Zo{\´e} and Errbii, Mohammed and Falabella, Patrizia and Gatti, Jean-Luc and Geuverink, Elzemiek and Gibson, Joshua D. and Hertaeg, Corinne and Hartmann, Stefanie and Jacquin-Joly, Emmanuelle and Lammers, Mark and Lavandero, Blas I. and Lindenbaum, Ina and Massardier-Galata, Lauriane and Meslin, Camille and Montagn{\´e}, Nicolas and Pak, Nina and Poiri{\´e}, Maryl{\`e}ne and Salvia, Rosanna and Smith, Chris R. and Tagu, Denis and Tares, Sophie and Vogel, Heiko and Schwander, Tanja and Simon, Jean-Christophe and Figueroa, Christian C. and Vorburger, Christoph and Legeai, Fabrice and Gadau, J{\"u}rgen},
title = {Functional insights from the GC-poor genomes of two aphid parasitoids, Aphidius ervi and Lysiphlebus fabarum},
series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
number = {989},
issn = {1866-8372},
doi = {10.25932/publishup-47612},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-476129},
pages = {29},
year = {2020},
abstract = {Background Parasitoid wasps have fascinating life cycles and play an important role in trophic networks, yet little is known about their genome content and function. Parasitoids that infect aphids are an important group with the potential for biological control. Their success depends on adapting to develop inside aphids and overcoming both host aphid defenses and their protective endosymbionts. Results We present the de novo genome assemblies, detailed annotation, and comparative analysis of two closely related parasitoid wasps that target pest aphids: Aphidius ervi and Lysiphlebus fabarum (Hymenoptera: Braconidae: Aphidiinae). The genomes are small (139 and 141 Mbp) and the most AT-rich reported thus far for any arthropod (GC content: 25.8 and 23.8\%). This nucleotide bias is accompanied by skewed codon usage and is stronger in genes with adult-biased expression. AT-richness may be the consequence of reduced genome size, a near absence of DNA methylation, and energy efficiency. We identify missing desaturase genes, whose absence may underlie mimicry in the cuticular hydrocarbon profile of L. fabarum. We highlight key gene groups including those underlying venom composition, chemosensory perception, and sex determination, as well as potential losses in immune pathway genes. Conclusions These findings are of fundamental interest for insect evolution and biological control applications. They provide a strong foundation for further functional studies into coevolution between parasitoids and their hosts. Both genomes are available at https://bipaa.genouest.org.},
language = {en}
}
@article{IzraylitGouldKratzetal.2020,
author = {Izraylit, Victor and Gould, Oliver E. C. and Kratz, Karl and Lendlein, Andreas},
title = {Investigating the phase-morphology of PLLA-PCL multiblock copolymer/PDLA blends cross-linked using stereocomplexation},
series = {MRS advances},
volume = {5},
journal = {MRS advances},
number = {14-15},
publisher = {Cambridge Univ. Press},
address = {New York},
issn = {2059-8521},
doi = {10.1557/adv.2019.465},
pages = {699 -- 707},
year = {2020},
abstract = {The macroscale function of multicomponent polymeric materials is dependent on their phase-morphology. Here, we investigate the morphological structure of a multiblock copolymer consisting of poly(L-lactide) and poly(epsilon-caprolactone) segments (PLLA-PCL), physically cross-linked by stereocomplexation with a low molecular weight poly(D-lactide) oligomer (PDLA). The effects of blend composition and PLLA-PCL molecular structure on the morphology are elucidated by AFM, TEM and SAXS. We identify the formation of a lattice pattern, composed of PLA domains within a PCL matrix, with an average domain spacing d0 = 12 - 19 nm. The size of the PLA domains were found to be proportional to the block length of the PCL segment of the copolymer and inversely proportional to the PDLA content of the blend. Changing the PLLA-PCL / PDLA ratio caused a shift in the melt transition Tm attributed to the PLA stereocomplex crystallites, indicating partial amorphous phase dilution of the PLA and PCL components within the semicrystalline material. By elucidating the phase structure and thermal character of multifunctional PLLA-PCL / PDLA blends, we illustrate how composition affects the internal structure and thermal properties of multicomponent polymeric materials. This study should facilitate the more effective incorporation of a variety of polymeric structural units capable of stimuli responsive phase transitions, where an understanding the phase-morphology of each component will enable the production of multifunctional soft-actuators with enhanced performance.},
language = {en}
}
@article{IzraylitHommesSchattmannNeffeetal.2020,
author = {Izraylit, Victor and Hommes-Schattmann, Paul Jacob and Neffe, Axel T. and Gould, Oliver E. C. and Lendlein, Andreas},
title = {Alkynyl-functionalized chain-extended PCL for coupling to biological molecules},
series = {European polymer journal},
volume = {136},
journal = {European polymer journal},
publisher = {Elsevier},
address = {Oxford},
issn = {0014-3057},
doi = {10.1016/j.eurpolymj.2020.109908},
pages = {11},
year = {2020},
abstract = {Chemical functionalization of poly(epsilon-caprolactone) (PCL) enables a molecular integration of additional function. Here, we report an approach to incorporate reactive alkynyl side-groups by synthesizing a chain-extended PCL, where the reactive site is introduced through the covalently functionalizable chain extender 3 (prop-2-yn-1-yloxy)propane-1,2-diol (YPD). Chain-extended PCL with M-w of 101 to 385 kg.mol(-1) were successfully synthesized in a one-pot reaction from PCL-diols with various molar masses, L-lysine ethyl ester diisocyanate (LDI) or trimethyl(hexamethylene)diisocyanate (TMDI), and YPD, in which the density of functionalizable groups and spacing between them can be controlled by the composition of the polymer. The employed diisocyanate compounds and YPD possess an asymmetric structure and form a non-crystallizable segment leaving the PCL crystallites to dominate the material's mechanical properties. The mixed glass transition temperature T-g = - 60 to - 46 degrees C of the PCL/polyurethane amorphous phase maintains the synthesized materials in a highly elastic state at ambient and physiological conditions. Reaction conditions for covalent attachment in copper(I)-catalyzed azide-alkyne-cycloaddition reactions (CuAAC) in solution were optimized in a series of model reactions between the alkyne moieties of the chain-extended PCL and benzyl azide, reaching conversions over 95\% of the alkyne moieties and with yields of up to 94\% for the purified functionalized PCL. This methodology was applied for reaction with the azide-functionalized cell adhesion peptide GRGDS. The required modification of the peptide provides selectivity in the coupling reactions. The obtained results suggest that YPD could potentially be employed as versatile molecular unit for the creation of a variety of functionalizable polyesters as well as polyurethanes and polycarbonates offering efficient and selective click-reactions.},
language = {en}
}
@article{IzraylitHommesSchattmannNeffeetal.2020,
author = {Izraylit, Victor and Hommes-Schattmann, Paul J. and Neffe, Axel T. and Gould, Oliver E. C. and Lendlein, Andreas},
title = {Polyester urethane functionalizable through maleimide side-chains and cross-linkable by polylactide stereocomplexes},
series = {European polymer journal},
volume = {137},
journal = {European polymer journal},
publisher = {Elsevier},
address = {Oxford},
issn = {0014-3057},
doi = {10.1016/j.eurpolymj.2020.109916},
pages = {8},
year = {2020},
abstract = {Sustainable multifunctional alternatives to fossil-derived materials, which can be functionalized and are degradable, can be envisioned by combining naturally derived starting materials with an established polymer design concept. Modularity and chemical flexibility of polyester urethanes (PEU) enable the combination of segments bearing functionalizable moieties and the tailoring of the mechanical and thermal properties. In this work, a PEU multiblock structure was synthesized from naturally derived L-lysine diisocyanate ethyl ester (LDI), poly(L-lactide) diol (PLLA) and N-(2,3-dihydroxypropyl)-maleimide (MID) in a one-step reaction. A maleimide side-chain (MID) provided a reactive site for the catalyst-free coupling of thiols shown for L-cysteine with a yield of 94\%. Physical cross-links were generated by blending the PEU with poly(D-lactide) (PDLA), upon which the PLLA segments of the PEU and the PDLA formed stereocomplexes. Stereocomplexation occurred spontaneously during solution casting and was investigated with WAXS and DSC. Stereocomplex crystallites were observed in the blends, while isotactic PLA crystallization was not observed. The presented material platform with tailorable mechanical properties by blending is of specific interest for engineering biointerfaces of implants or carrier systems for bioactive molecules.},
language = {en}
}
@article{HalilbasicFuerstHeidenetal.2020,
author = {Halilbasic, Emina and Fuerst, Elisabeth and Heiden, Denise and Japtok, Lukasz and Diesner, Susanne C. and Trauner, Michael and Kulu, Askin and Jaksch, Peter and Hoetzenecker, Konrad and Kleuser, Burkhard and Kazemi-Shirazi, Lili and Untersmayr, Eva},
title = {Plasma levels of the bioactive sphingolipid metabolite S1P in adult cystic fibrosis patients},
series = {Nutrients},
volume = {12},
journal = {Nutrients},
number = {3},
publisher = {MDPI},
address = {Basel},
issn = {2072-6643},
doi = {10.3390/nu12030765},
pages = {11},
year = {2020},
abstract = {Recent research has linked sphingolipid (SL) metabolism with cystic fibrosis transmembrane conductance regulator (CFTR) activity, affecting bioactive lipid mediator sphingosine-1-phosphate (S1P). We hypothesize that loss of CFTR function in cystic fibrosis (CF) patients influenced plasma S1P levels. Total and unbound plasma S1P levels were measured in 20 lung-transplanted adult CF patients and 20 healthy controls by mass spectrometry and enzyme-linked immunosorbent assay (ELISA). S1P levels were correlated with CFTR genotype, routine laboratory parameters, lung function and pathogen colonization, and clinical symptoms. Compared to controls, CF patients showed lower unbound plasma S1P, whereas total S1P levels did not differ. A positive correlation of total and unbound S1P levels was found in healthy controls, but not in CF patients. Higher unbound S1P levels were measured in Delta F508-homozygous compared to Delta F508-heterozygous CF patients (p = 0.038), accompanied by higher levels of HDL in Delta F508-heterozygous patients. Gastrointestinal symptoms were more common in Delta F508 heterozygotes compared to Delta F508 homozygotes. This is the first clinical study linking plasma S1P levels with CFTR function and clinical presentation in adult CF patients. Given the emerging role of immunonutrition in CF, our study might pave the way for using S1P as a novel biomarker and nutritional target in CF.},
language = {en}
}
@article{LiuGouldRudolphetal.2020,
author = {Liu, Yue and Gould, Oliver E. C. and Rudolph, Tobias and Fang, Liang and Kratz, Karl and Lendlein, Andreas},
title = {Polymeric microcuboids programmable for temperature-memory},
series = {Macromolecular materials and engineering},
volume = {305},
journal = {Macromolecular materials and engineering},
number = {10},
publisher = {Wiley-VCH},
address = {Weinheim},
issn = {1438-7492},
doi = {10.1002/mame.202000333},
pages = {7},
year = {2020},
abstract = {Microobjects with programmable mechanical functionality are highly desirable for the creation of flexible electronics, sensors, and microfluidic systems, where fabrication/programming and quantification methods are required to fully control and implement dynamic physical behavior. Here, programmable microcuboids with defined geometries are prepared by a template-based method from crosslinked poly[ethylene-co-(vinyl acetate)] elastomers. These microobjects could be programmed to exhibit a temperature-memory effect or a shape-memory polymer actuation capability. Switching temperaturesT(sw)during shape recovery of 55 +/- 2, 68 +/- 2, 80 +/- 2, and 86 +/- 2 degrees C are achieved by tuning programming temperatures to 55, 70, 85, and 100 degrees C, respectively. Actuation is achieved with a reversible strain of 2.9 +/- 0.2\% to 6.7 +/- 0.1\%, whereby greater compression ratios and higher separation temperatures induce a more pronounced actuation. Micro-geometry change is quantified using optical microscopy and atomic force microscopy. The realization and quantification of microparticles, capable of a tunable temperature responsive shape-change or reversible actuation, represent a key development in the creation of soft microscale devices for drug delivery or microrobotics.},
language = {en}
}
@article{DolcosKatsumiBogdanetal.2020,
author = {Dolcos, Florin and Katsumi, Yuta and Bogdan, Paul C. and Shen, Chen and Jun, Suhnyoung and Buetti, Simona and Lleras, Alejandro and Bost, Kelly Freeman and Weymar, Mathias and Dolcos, Sanda},
title = {The impact of focused attention on subsequent emotional recollection},
series = {Neuropsychologia : an international journal in behavioural and cognitive neuroscience},
volume = {138},
journal = {Neuropsychologia : an international journal in behavioural and cognitive neuroscience},
publisher = {Elsevier},
address = {Oxford},
issn = {0028-3932},
doi = {10.1016/j.neuropsychologia.2020.107338},
pages = {12},
year = {2020},
abstract = {In his seminal works, Endel Tulving argued that functionally distinct memory systems give rise to subjective experiences of remembering and knowing (i.e., recollection- vs. familiarity-based memory, respectively). Evidence shows that emotion specifically enhances recollection, and this effect is subserved by a synergistic mechanism involving the amygdala (AMY) and hippocampus (HC). In extreme circumstances, however, uncontrolled recollection of highly distressing memories may lead to symptoms of affective disorders. Therefore, it is important to understand the factors that can diminish such detrimental effects. Here, we investigated the effects of Focused Attention (FA) on emotional recollection. FA is an emotion regulation strategy that has been proven quite effective in reducing the impact of emotional responses associated with the recollection of distressing autobiographical memories, but its impact during emotional memory encoding is not known. Functional MRI and eye-tracking data were recorded while participants viewed a series of composite negative and neutral images with distinguishable foreground (FG) and background (BG) areas. Participants were instructed to focus either on the FG or BG content of the images and to rate their emotional responses. About 4 days later, participants' memory was assessed using the R/K procedure, to indicate whether they Recollected specific contextual details about the encoded images or the images were just familiar to them - i.e., participants only Knew that they saw the pictures without being able to remember specific contextual details. First, results revealed that FA was successful in decreasing memory for emotional pictures viewed in BG Focus condition, and this effect was driven by recollection-based retrieval. Second, the BG Focus condition was associated with decreased activity in the AMY, HC, and anterior parahippocampal gyrus for subsequently recollected emotional items. Moreover, correlation analyses also showed that reduced activity in these regions predicted greater reduction in emotional recollection following FA. These results demonstrate the effectiveness of FA in mitigating emotional experiences and emotional recollection associated with unpleasant emotional events.},
language = {en}
}
@article{ZhouAitchisonLokhoetal.2020,
author = {Zhou, Renjie and Aitchison, Jonathan C. and Lokho, Kapesa and Sobel, Edward and Feng, Yuexing and Zhao, Jian-xin},
title = {Unroofing the Ladakh Batholith: constraints from autochthonous molasse of the Indus Basin, NW Himalaya},
series = {Journal of the Geological Society},
volume = {177},
journal = {Journal of the Geological Society},
number = {4},
publisher = {Geological Society (London)},
address = {London},
issn = {0016-7649},
doi = {10.1144/jgs2019-188},
pages = {818 -- 825},
year = {2020},
abstract = {The Indus Molasse records orogenic sedimentation associated with uplift and erosion of the southern margin of Asia in the course of ongoing India-Eurasia collision. Detailed field investigation clarifies the nature and extent of the depositional contact between this molasse and the underlying basement units. We report the first dataset on detrital zircon U-Pb ages, Hf isotopes and apatite U-Pb ages for the autochthonous molasse in the Indus Suture Zone. A latest Oligocene depositional age is proposed on the basis of the youngest detrital zircon U-Pb age peak and is consistent with published biostratigraphic data. Multiple provenance indicators suggest exclusively northerly derivation with no input from India in the lowermost parts of the section. The results provide constraints on the uplift and erosion history of the Ladakh Range following the initial India-Asia collision.},
language = {en}
}
@misc{RamirezCampilloAndradeNikolaidisetal.2020,
author = {Ramirez-Campillo, Rodrigo and Andrade, David C. and Nikolaidis, Pantelis T. and Moran, Jason and Clemente, Filipe Manuel and Chaabene, Helmi and Comfort, Paul},
title = {Effects of plyometric jump training on vertical jump height of volleyball players: a systematic review with meta-analysis of randomized-controlled trial},
series = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
issn = {1866-8364},
doi = {10.25932/publishup-52589},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-525898},
pages = {13},
year = {2020},
abstract = {This meta-analysis aimed to assess the effects of plyometric jump training (PJT) on volleyball players' vertical jump height (VJH), comparing changes with those observed in a matched control group. A literature search in the databases of PubMed, MEDLINE, Web of Science, and SCOPUS was conducted. Only randomized-controlled trials and studies that included a pre-to-post intervention assessment of VJH were included. They involved only healthy volleyball players with no restrictions on age or sex. Data were independently extracted from the included studies by two authors. The Physiotherapy Evidence Database scale was used to assess the risk of bias, and methodological quality, of eligible studies included in the review. From 7,081 records, 14 studies were meta-analysed. A moderate Cohen's d effect size (ES = 0.82, p <0.001) was observed for VJH, with moderate heterogeneity (I2 = 34.4\%, p = 0.09) and no publication bias (Egger's test, p = 0.59). Analyses of moderator variables revealed no significant differences for PJT program duration (≤8 vs. >8 weeks, ES = 0.79 vs. 0.87, respectively), frequency (≤2 vs. >2 sessions/week, ES = 0.83 vs. 0.78, respectively), total number of sessions (≤16 vs. >16 sessions, ES = 0.73 vs. 0.92, respectively), sex (female vs. male, ES = 1.3 vs. 0.5, respectively), age (≥19 vs. <19 years of age, ES = 0.89 vs. 0.70, respectively), and volume (>2,000 vs. <2,000 jumps, ES = 0.76 vs. 0.79, respectively). In conclusion, PJT appears to be effective in inducing improvements in volleyball players' VJH. Improvements in VJH may be achieved by both male and female volleyball players, in different age groups, with programs of relatively low volume and frequency. Though PJT seems to be safe for volleyball players, it is recommended that an individualized approach, according to player position, is adopted with some players (e.g. libero) less prepared to sustain PJT loads.},
language = {en}
}
@article{RamirezCampilloAndradeNikolaidisetal.2020,
author = {Ramirez-Campillo, Rodrigo and Andrade, David C. and Nikolaidis, Pantelis T. and Moran, Jason and Clemente, Filipe Manuel and Chaabene, Helmi and Comfort, Paul},
title = {Effects of plyometric jump training on vertical jump height of volleyball players: a systematic review with meta-analysis of randomized-controlled trial},
series = {Journal of Sports Science and Medicine},
volume = {19},
journal = {Journal of Sports Science and Medicine},
publisher = {Wiley-Blackwell},
address = {Oxford},
pages = {11},
year = {2020},
abstract = {This meta-analysis aimed to assess the effects of plyometric jump training (PJT) on volleyball players' vertical jump height (VJH), comparing changes with those observed in a matched control group. A literature search in the databases of PubMed, MEDLINE, Web of Science, and SCOPUS was conducted. Only randomized-controlled trials and studies that included a pre-to-post intervention assessment of VJH were included. They involved only healthy volleyball players with no restrictions on age or sex. Data were independently extracted from the included studies by two authors. The Physiotherapy Evidence Database scale was used to assess the risk of bias, and methodological quality, of eligible studies included in the review. From 7,081 records, 14 studies were meta-analysed. A moderate Cohen's d effect size (ES = 0.82, p <0.001) was observed for VJH, with moderate heterogeneity (I2 = 34.4\%, p = 0.09) and no publication bias (Egger's test, p = 0.59). Analyses of moderator variables revealed no significant differences for PJT program duration (≤8 vs. >8 weeks, ES = 0.79 vs. 0.87, respectively), frequency (≤2 vs. >2 sessions/week, ES = 0.83 vs. 0.78, respectively), total number of sessions (≤16 vs. >16 sessions, ES = 0.73 vs. 0.92, respectively), sex (female vs. male, ES = 1.3 vs. 0.5, respectively), age (≥19 vs. <19 years of age, ES = 0.89 vs. 0.70, respectively), and volume (>2,000 vs. <2,000 jumps, ES = 0.76 vs. 0.79, respectively). In conclusion, PJT appears to be effective in inducing improvements in volleyball players' VJH. Improvements in VJH may be achieved by both male and female volleyball players, in different age groups, with programs of relatively low volume and frequency. Though PJT seems to be safe for volleyball players, it is recommended that an individualized approach, according to player position, is adopted with some players (e.g. libero) less prepared to sustain PJT loads.},
language = {en}
}
@article{HerreroThorntonMasonD'Crozetal.2020,
author = {Herrero, Mario and Thornton, Philip K. and Mason-D'Croz, Daniel and Palmer, Jeda and Bodirsky, Benjamin Leon and Pradhan, Prajal and Barrett, Christopher B. and Benton, Tim G. and Hall, Andrew and Pikaar, Ilje and Bogard, Jessica R. and Bonnett, Graham D. and Bryan, Brett A. and Campbell, Bruce M. and Christensen, Svend and Clark, Michael and Fanzo, Jessica and Godde, Cecile M. and Jarvis, Andy and Loboguerrero, Ana Maria and Mathys, Alexander and McIntyre, C. Lynne and Naylor, Rosamond L. and Nelson, Rebecca and Obersteiner, Michael and Parodi, Alejandro and Popp, Alexander and Ricketts, Katie and Smith, Pete and Valin, Hugo and Vermeulen, Sonja J. and Vervoort, Joost and van Wijk, Mark and van Zanten, Hannah H. E. and West, Paul C. and Wood, Stephen A. and Rockstr{\"o}m, Johan},
title = {Articulating the effect of food systems innovation on the Sustainable Development Goals},
series = {The lancet Planetary health},
volume = {5},
journal = {The lancet Planetary health},
number = {1},
publisher = {Elsevier},
address = {Oxford},
issn = {2542-5196},
doi = {10.1016/S2542-5196(20)30277-1},
pages = {E50 -- E62},
year = {2020},
abstract = {Food system innovations will be instrumental to achieving multiple Sustainable Development Goals (SDGs). However, major innovation breakthroughs can trigger profound and disruptive changes, leading to simultaneous and interlinked reconfigurations of multiple parts of the global food system. The emergence of new technologies or social solutions, therefore, have very different impact profiles, with favourable consequences for some SDGs and unintended adverse side-effects for others. Stand-alone innovations seldom achieve positive outcomes over multiple sustainability dimensions. Instead, they should be embedded as part of systemic changes that facilitate the implementation of the SDGs. Emerging trade-offs need to be intentionally addressed to achieve true sustainability, particularly those involving social aspects like inequality in its many forms, social justice, and strong institutions, which remain challenging. Trade-offs with undesirable consequences are manageable through the development of well planned transition pathways, careful monitoring of key indicators, and through the implementation of transparent science targets at the local level.},
language = {en}
}
@article{LehmannZhengRyoetal.2020,
author = {Lehmann, Anika and Zheng, Weishuang and Ryo, Masahiro and Soutschek, Katharina and Roy, Julien and Rongstock, Rebecca and Maaß, Stefanie and Rillig, Matthias C.},
title = {Fungal traits important for soil aggregation},
series = {Frontiers in microbiology},
volume = {10},
journal = {Frontiers in microbiology},
publisher = {Frontiers Media},
address = {Lausanne},
issn = {1664-302X},
doi = {10.3389/fmicb.2019.02904},
pages = {13},
year = {2020},
abstract = {Soil structure, the complex arrangement of soil into aggregates and pore spaces, is a key feature of soils and soil biota. Among them, filamentous saprobic fungi have well-documented effects on soil aggregation. However, it is unclear what properties, or traits, determine the overall positive effect of fungi on soil aggregation. To achieve progress, it would be helpful to systematically investigate a broad suite of fungal species for their trait expression and the relation of these traits to soil aggregation. Here, we apply a trait-based approach to a set of 15 traits measured under standardized conditions on 31 fungal strains including Ascomycota, Basidiomycota, and Mucoromycota, all isolated from the same soil. We find large differences among these fungi in their ability to aggregate soil, including neutral to positive effects, and we document large differences in trait expression among strains. We identify biomass density, i.e., the density with which a mycelium grows (positive effects), leucine aminopeptidase activity (negative effects) and phylogeny as important factors explaining differences in soil aggregate formation (SAF) among fungal strains; importantly, growth rate was not among the important traits. Our results point to a typical suite of traits characterizing fungi that are good soil aggregators, and our findings illustrate the power of employing a trait-based approach to unravel biological mechanisms underpinning soil aggregation. Such an approach could now be extended also to other soil biota groups. In an applied context of restoration and agriculture, such trait information can inform management, for example to prioritize practices that favor the expression of more desirable fungal traits.},
language = {en}
}
@article{RilligBielcikChaudharyetal.2020,
author = {Rillig, Matthias C. and Bielcik, Milos and Chaudhary, Veer Bala and Gr{\"u}nfeld, Leonie and Maass, Stefanie and Mansour, India and Ryo, Masahiro and Veresoglou, Stavros D.},
title = {Ten simple rules for increased lab resilience},
series = {PLoS Computational Biology : a new community journal},
volume = {16},
journal = {PLoS Computational Biology : a new community journal},
number = {11},
publisher = {PLoS},
address = {San Fransisco},
issn = {1553-734X},
doi = {10.1371/journal.pcbi.1008313},
pages = {5},
year = {2020},
abstract = {When running a lab we do not think about calamities, since they are rare events for which we cannot plan while we are busy with the day-to-day management and intellectual challenges of a research lab. No lab team can be prepared for something like a pandemic such as COVID-19, which has led to shuttered labs around the globe. But many other types of crises can also arise that labs may have to weather during their lifetime. What can researchers do to make a lab more resilient in the face of such exterior forces? What systems or behaviors could we adjust in 'normal' times that promote lab success, and increase the chances that the lab will stay on its trajectory? We offer 10 rules, based on our current experiences as a lab group adapting to crisis.},
language = {en}
}
@article{QiuBenjaminRamanVenkatesanetal.2020,
author = {Qiu, Xunlin and Benjamin, Aravindan Joseph and Raman Venkatesan, Thulasinath and Schmidt, Georg C. and Soler, Ricardo Alonso Quintana and Panicker, Pramul Muraleedhara and Gerhard, Reimund and H{\"u}bler, Arved Carl},
title = {Dielectric and electroacoustic assessment of screen-printed piezoelectric polymer layers as flexible transducers},
series = {IEEE transactions on dielectrics and electrical insulation},
volume = {27},
journal = {IEEE transactions on dielectrics and electrical insulation},
number = {5},
publisher = {Institute of Electrical and Electronics Engineers},
address = {New York, NY},
issn = {1070-9878},
doi = {10.1109/TDEI.2020.008864},
pages = {1683 -- 1690},
year = {2020},
abstract = {Here, piezoelectric transducers consisting of a P(VDF-TrFE) layer with either silver or PEDOT:PSS screen-printed electrodes are studied. The influence of electrodes on the dielectric and electroacoustic properties are studied in dielectric-spectroscopy and ferroelectric-hysteresis measurements. Only when both the bottom and the top electrodes are made of silver, the typical dielectric relaxation of the P(VDF-TrFE) layer is clearly observed. When one or two of the electrodes are of PEDOT:PSS, a Debye-like relaxation is present. Compared with silver electrodes, PEDOT:PSS electrodes allow for moderate self-healing. Consequently, samples with bottom and top PEDOT:PSS electrodes can be poled to saturation, while samples with silver electrodes can hardly be poled to saturation due to destructive electric breakdown. Acoustic transducer measurements show that silver electrodes facilitate higher and broader frequency operation, while PEDOT:PSS electrodes bring slightly lower total harmonic distortion. Overall, the acoustic performance shows no significant deviations between differently electroded samples so that silver electrodes do not offer any advantages for the transducers studied here due to their much higher tendency for destructive electric breakdown.},
language = {en}
}
@article{AssagraAltafimdoCarmoetal.2020,
author = {Assagra, Yuri A.O. and Altafim, Ruy Alberto Pisani and do Carmo, Joao P. and Altafim, Ruy A.C. and Rychkov, Dmitry and Wirges, Werner and Gerhard, Reimund},
title = {A new route to piezo-polymer transducers: 3D printing of polypropylene ferroelectrets},
series = {IEEE transactions on dielectrics and electrical insulation},
volume = {27},
journal = {IEEE transactions on dielectrics and electrical insulation},
number = {5},
publisher = {Inst. of Electr. and Electronics Engineers},
address = {Piscataway},
issn = {1070-9878},
doi = {10.1109/TDEI.2020.008461},
pages = {1668 -- 1674},
year = {2020},
abstract = {Here, a promising approach for producing piezo-polymer transducers in a one-step process is presented. Using 3D-printing technology and polypropylene (PP) filaments, we are able to print a two-layered film structure with regular cavities of precisely controlled size and shape. It is found that the 3D-printed samples exhibit piezoelectric coefficients up to 200 pC/N, similar to those of other PP ferroelectrets, and their temporal and thermal behavior is in good agreement with those known of PP ferroelectrets. The piezoelectric response strongly decreases for applied pressures above 20 kPa, as the pressure in the air-filled cavities strongly influences the overall elastic modulus of ferroelectrets.},
language = {en}
}
@misc{GriscomBuschCookPattonetal.2020,
author = {Griscom, Bronson W. and Busch, Jonah and Cook-Patton, Susan C. and Ellis, Peter W. and Funk, Jason and Leavitt, Sara M. and Lomax, Guy and Turner, Will R. and Chapman, Melissa and Streck, Charlotte},
title = {National mitigation potential from natural climate solutions in the tropics},
series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe},
journal = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe},
number = {1794},
issn = {1867-5808},
doi = {10.25932/publishup-51369},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-513692},
pages = {13},
year = {2020},
abstract = {Better land stewardship is needed to achieve the Paris Agreement's temperature goal, particularly in the tropics, where greenhouse gas emissions from the destruction of ecosystems are largest, and where the potential for additional land carbon storage is greatest. As countries enhance their nationally determined contributions (NDCs) to the Paris Agreement, confusion persists about the potential contribution of better land stewardship to meeting the Agreement's goal to hold global warming below 2 degrees C. We assess cost-effective tropical country-level potential of natural climate solutions (NCS)-protection, improved management and restoration of ecosystems-to deliver climate mitigation linked with sustainable development goals (SDGs). We identify groups of countries with distinctive NCS portfolios, and we explore factors (governance, financial capacity) influencing the feasibility of unlocking national NCS potential. Cost-effective tropical NCS offers globally significant climate mitigation in the coming decades (6.56 Pg CO(2)e yr(-1) at less than 100 US\$ per Mg CO(2)e). In half of the tropical countries, cost-effective NCS could mitigate over half of national emissions. In more than a quarter of tropical countries, cost-effective NCS potential is greater than national emissions. We identify countries where, with international financing and political will, NCS can cost-effectively deliver the majority of enhanced NDCs while transforming national economies and contributing to SDGs. This article is part of the theme issue 'Climate change and ecosystems: threats, opportunities and solutions'.},
language = {en}
}
@misc{FosterGarvieWeissetal.2020,
author = {Foster, William J. and Garvie, Christopher L. and Weiss, Anna M. and Muscente, A. Drew and Aberhan, Martin and Counts, John W. and Martindale, Rowan C.},
title = {Resilience of marine invertebrate communities during the early Cenozoic hyperthermals},
series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
journal = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
number = {1},
issn = {1866-8372},
doi = {10.25932/publishup-51601},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-516011},
pages = {13},
year = {2020},
abstract = {The hyperthermal events of the Cenozoic, including the Paleocene-Eocene Thermal Maximum, provide an opportunity to investigate the potential effects of climate warming on marine ecosystems. Here, we examine the shallow benthic marine communities preserved in the late Cretaceous to Eocene strata on the Gulf Coastal Plain (United States). In stark contrast to the ecological shifts following the end-Cretaceous mass extinction, our data show that the early Cenozoic hyperthermals did not have a long-term impact on the generic diversity nor composition of the Gulf Coastal Plain molluscan communities. We propose that these communities were resilient to climate change because molluscs are better adapted to high temperatures than other taxa, as demonstrated by their physiology and evolutionary history. In terms of resilience, these communities differ from other shallow-water carbonate ecosystems, such as reef communities, which record significant changes during the early Cenozoic hyperthermals. These data highlight the strikingly different responses of community types, i.e., the almost imperceptible response of molluscs versus the marked turnover of foraminifera and reef faunas. The impact on molluscan communities may have been low because detrimental conditions did not devastate the entire Gulf Coastal Plain, allowing molluscs to rapidly recolonise vacated areas once harsh environmental conditions ameliorated.},
language = {en}
}
@article{FosterGarvieWeissetal.2020,
author = {Foster, William J. and Garvie, Christopher L. and Weiss, Anna M. and Muscente, A. Drew and Aberhan, Martin and Counts, John W. and Martindale, Rowan C.},
title = {Resilience of marine invertebrate communities during the early Cenozoic hyperthermals},
series = {Scientific Reports},
volume = {10},
journal = {Scientific Reports},
number = {1},
publisher = {Springer Nature},
address = {London},
issn = {2045-2322},
doi = {10.1038/s41598-020-58986-5},
pages = {1 -- 11},
year = {2020},
abstract = {The hyperthermal events of the Cenozoic, including the Paleocene-Eocene Thermal Maximum, provide an opportunity to investigate the potential effects of climate warming on marine ecosystems. Here, we examine the shallow benthic marine communities preserved in the late Cretaceous to Eocene strata on the Gulf Coastal Plain (United States). In stark contrast to the ecological shifts following the end-Cretaceous mass extinction, our data show that the early Cenozoic hyperthermals did not have a long-term impact on the generic diversity nor composition of the Gulf Coastal Plain molluscan communities. We propose that these communities were resilient to climate change because molluscs are better adapted to high temperatures than other taxa, as demonstrated by their physiology and evolutionary history. In terms of resilience, these communities differ from other shallow-water carbonate ecosystems, such as reef communities, which record significant changes during the early Cenozoic hyperthermals. These data highlight the strikingly different responses of community types, i.e., the almost imperceptible response of molluscs versus the marked turnover of foraminifera and reef faunas. The impact on molluscan communities may have been low because detrimental conditions did not devastate the entire Gulf Coastal Plain, allowing molluscs to rapidly recolonise vacated areas once harsh environmental conditions ameliorated.},
language = {en}
}
@article{McNultyGoupilAlbaradoetal.2020,
author = {McNulty, Margaret A. and Goupil, Brad A. and Albarado, Diana C. and Casta{\~n}o-Martinez, Teresa and Ambrosi, Thomas H. and Puh, Spela and Schulz, Tim Julius and Sch{\"u}rmann, Annette and Morrison, Christopher D. and Laeger, Thomas},
title = {FGF21, not GCN2, influences bone morphology due to dietary protein restrictions},
series = {Bone Reports},
volume = {12},
journal = {Bone Reports},
publisher = {Elsevier},
address = {Amsterdam},
issn = {2352-1872},
doi = {10.1016/j.bonr.2019.100241},
pages = {1 -- 10},
year = {2020},
abstract = {Background: Dietary protein restriction is emerging as an alternative approach to treat obesity and glucose intolerance because it markedly increases plasma fibroblast growth factor 21 (FGF21) concentrations. Similarly, dietary restriction of methionine is known to mimic metabolic effects of energy and protein restriction with FGF21 as a required mechanism. However, dietary protein has been shown to be required for normal bone growth, though there is conflicting evidence as to the influence of dietary protein restriction on bone remodeling. The purpose of the current study was to evaluate the effect of dietary protein and methionine restriction on bone in lean and obese mice, and clarify whether FGF21 and general control nonderepressible 2 (GCN2) kinase, that are part of a novel endocrine pathway implicated in the detection of protein restriction, influence the effect of dietary protein restriction on bone. Methods: Adult wild-type (WT) or Fgf21 KO mice were fed a normal protein (18 kcal\%; CON) or low protein (4 kcal\%; LP) diet for 2 or 27 weeks. In addition, adult WT or Gcn2 KO mice were fed a CON or LP diet for 27 weeks. Young New Zealand obese (NZO) mice were placed on high-fat diets that provided protein at control (16 kcal\%; CON), low levels (4 kcal\%) in a high-carbohydrate (LP/HC) or high-fat (LP/HF) regimen, or on high-fat diets (protein, 16 kcal\%) that provided methionine at control (0.86\%; CON-MR) or low levels (0.17\%; MR) for up to 9 weeks. Long bones from the hind limbs of these mice were collected and evaluated with micro-computed tomography (mu CT) for changes in trabecular and cortical architecture and mass. Results: In WT mice the 27-week LP diet significantly reduced cortical bone, and this effect was enhanced by deletion of Fgf21 but not Gcn2. This decrease in bone did not appear after 2 weeks on the LP diet. In addition, Fgf21 KO mice had significantly less bone than their WT counterparts. In obese NZO mice dietary protein and methionine restriction altered bone architecture. The changes were mediated by FGF21 due to methionine restriction in the presence of cystine, which did not increase plasma FGF21 levels and did not affect bone architecture. Conclusions: This study provides direct evidence of a reduction in bone following long-term dietary protein restriction in a mouse model, effects that appear to be mediated by FGF21.},
language = {en}
}
@article{HortonKhanCahilletal.2020,
author = {Horton, Benjamin P. and Khan, Nicole S. and Cahill, Niamh and Lee, Janice S. H. and Shaw, Timothy A. and Garner, Andra J. and Kemp, Andrew C. and Engelhart, Simon E. and Rahmstorf, Stefan},
title = {Estimating global mean sea-level rise and its uncertainties by 2100 and 2300 from an expert survey},
series = {npj Climate and Atmospheric Science},
volume = {3},
journal = {npj Climate and Atmospheric Science},
number = {1},
publisher = {Springer Nature},
address = {London},
issn = {2397-3722},
doi = {10.1038/s41612-020-0121-5},
pages = {1 -- 8},
year = {2020},
abstract = {Sea-level rise projections and knowledge of their uncertainties are vital to make informed mitigation and adaptation decisions. To elicit projections from members of the scientific community regarding future global mean sea-level (GMSL) rise, we repeated a survey originally conducted five years ago. Under Representative Concentration Pathway (RCP) 2.6, 106 experts projected a likely (central 66\% probability) GMSL rise of 0.30-0.65 m by 2100, and 0.54-2.15 m by 2300, relative to 1986-2005. Under RCP 8.5, the same experts projected a likely GMSL rise of 0.63-1.32 m by 2100, and 1.67-5.61 m by 2300. Expert projections for 2100 are similar to those from the original survey, although the projection for 2300 has extended tails and is higher than the original survey. Experts give a likelihood of 42\% (original survey) and 45\% (current survey) that under the high-emissions scenario GMSL rise will exceed the upper bound (0.98 m) of the likely range estimated by the Fifth Assessment Report of the Intergovernmental Panel on Climate Change, which is considered to have an exceedance likelihood of 17\%. Responses to open-ended questions suggest that the increases in upper-end estimates and uncertainties arose from recent influential studies about the impact of marine ice cliff instability on the meltwater contribution to GMSL rise from the Antarctic Ice Sheet.},
language = {en}
}
@misc{McNultyGoupilAlbaradoetal.2020,
author = {McNulty, Margaret A. and Goupil, Brad A. and Albarado, Diana C. and Casta{\~n}o-Martinez, Teresa and Ambrosi, Thomas H. and Puh, Spela and Schulz, Tim Julius and Sch{\"u}rmann, Annette and Morrison, Christopher D. and Laeger, Thomas},
title = {FGF21, not GCN2, influences bone morphology due to dietary protein restrictions},
series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
journal = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
issn = {1866-8372},
doi = {10.25932/publishup-51629},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-516297},
pages = {12},
year = {2020},
abstract = {Background: Dietary protein restriction is emerging as an alternative approach to treat obesity and glucose intolerance because it markedly increases plasma fibroblast growth factor 21 (FGF21) concentrations. Similarly, dietary restriction of methionine is known to mimic metabolic effects of energy and protein restriction with FGF21 as a required mechanism. However, dietary protein has been shown to be required for normal bone growth, though there is conflicting evidence as to the influence of dietary protein restriction on bone remodeling. The purpose of the current study was to evaluate the effect of dietary protein and methionine restriction on bone in lean and obese mice, and clarify whether FGF21 and general control nonderepressible 2 (GCN2) kinase, that are part of a novel endocrine pathway implicated in the detection of protein restriction, influence the effect of dietary protein restriction on bone. Methods: Adult wild-type (WT) or Fgf21 KO mice were fed a normal protein (18 kcal\%; CON) or low protein (4 kcal\%; LP) diet for 2 or 27 weeks. In addition, adult WT or Gcn2 KO mice were fed a CON or LP diet for 27 weeks. Young New Zealand obese (NZO) mice were placed on high-fat diets that provided protein at control (16 kcal\%; CON), low levels (4 kcal\%) in a high-carbohydrate (LP/HC) or high-fat (LP/HF) regimen, or on high-fat diets (protein, 16 kcal\%) that provided methionine at control (0.86\%; CON-MR) or low levels (0.17\%; MR) for up to 9 weeks. Long bones from the hind limbs of these mice were collected and evaluated with micro-computed tomography (mu CT) for changes in trabecular and cortical architecture and mass. Results: In WT mice the 27-week LP diet significantly reduced cortical bone, and this effect was enhanced by deletion of Fgf21 but not Gcn2. This decrease in bone did not appear after 2 weeks on the LP diet. In addition, Fgf21 KO mice had significantly less bone than their WT counterparts. In obese NZO mice dietary protein and methionine restriction altered bone architecture. The changes were mediated by FGF21 due to methionine restriction in the presence of cystine, which did not increase plasma FGF21 levels and did not affect bone architecture. Conclusions: This study provides direct evidence of a reduction in bone following long-term dietary protein restriction in a mouse model, effects that appear to be mediated by FGF21.},
language = {en}
}
@misc{DengWangXuaetal.2020,
author = {Deng, Zijun and Wang, Weiwei and Xua, Xun and Gould, Oliver E. C. and Kratz, Karl and Ma, Nan and Lendlein, Andreas},
title = {Polymeric sheet actuators with programmable bioinstructivity},
series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
journal = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
number = {4},
issn = {1866-8372},
doi = {10.25932/publishup-51549},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-515490},
pages = {9},
year = {2020},
abstract = {Stem cells are capable of sensing and processing environmental inputs, converting this information to output a specific cell lineage through signaling cascades. Despite the combinatorial nature of mechanical, thermal, and biochemical signals, these stimuli have typically been decoupled and applied independently, requiring continuous regulation by controlling units. We employ a programmable polymer actuator sheet to autonomously synchronize thermal and mechanical signals applied to mesenchymal stem cells (MSC5). Using a grid on its underside, the shape change of polymer sheet, as well as cell morphology, calcium (Ca2+) influx, and focal adhesion assembly, could be visualized and quantified. This paper gives compelling evidence that the temperature sensing and mechanosensing of MSC5 are interconnected via intracellular Ca2+. Up-regulated Ca2+ levels lead to a remarkable alteration of histone H3K9 acetylation and activation of osteogenic related genes. The interplay of physical, thermal, and biochemical signaling was utilized to accelerate the cell differentiation toward osteogenic lineage. The approach of programmable bioinstructivity provides a fundamental principle for functional biomaterials exhibiting multifaceted stimuli on differentiation programs. Technological impact is expected in the tissue engineering of periosteum for treating bone defects.},
language = {en}
}
@misc{HortonKhanCahilletal.2020,
author = {Horton, Benjamin P. and Khan, Nicole S. and Cahill, Niamh and Lee, Janice S. H. and Shaw, Timothy A. and Garner, Andra J. and Kemp, Andrew C. and Engelhart, Simon E. and Rahmstorf, Stefan},
title = {Estimating global mean sea-level rise and its uncertainties by 2100 and 2300 from an expert survey},
series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
journal = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
number = {1},
issn = {1866-8372},
doi = {10.25932/publishup-51678},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-516788},
pages = {10},
year = {2020},
abstract = {Sea-level rise projections and knowledge of their uncertainties are vital to make informed mitigation and adaptation decisions. To elicit projections from members of the scientific community regarding future global mean sea-level (GMSL) rise, we repeated a survey originally conducted five years ago. Under Representative Concentration Pathway (RCP) 2.6, 106 experts projected a likely (central 66\% probability) GMSL rise of 0.30-0.65 m by 2100, and 0.54-2.15 m by 2300, relative to 1986-2005. Under RCP 8.5, the same experts projected a likely GMSL rise of 0.63-1.32 m by 2100, and 1.67-5.61 m by 2300. Expert projections for 2100 are similar to those from the original survey, although the projection for 2300 has extended tails and is higher than the original survey. Experts give a likelihood of 42\% (original survey) and 45\% (current survey) that under the high-emissions scenario GMSL rise will exceed the upper bound (0.98 m) of the likely range estimated by the Fifth Assessment Report of the Intergovernmental Panel on Climate Change, which is considered to have an exceedance likelihood of 17\%. Responses to open-ended questions suggest that the increases in upper-end estimates and uncertainties arose from recent influential studies about the impact of marine ice cliff instability on the meltwater contribution to GMSL rise from the Antarctic Ice Sheet.},
language = {en}
}
@article{ChristakoudiTsilidisMulleretal.2020,
author = {Christakoudi, Sofa and Tsilidis, Konstantinos K. and Muller, David C. and Freisling, Heinz and Weiderpass, Elisabete and Overvad, Kim and S{\"o}derberg, Stefan and H{\"a}ggstr{\"o}m, Christel and Pischon, Tobias and Dahm, Christina C. and Zhang, Jie and Tj{\o}nneland, Anne and Schulze, Matthias Bernd},
title = {A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort},
series = {Scientific Reports},
volume = {10},
journal = {Scientific Reports},
number = {1},
publisher = {Springer Nature},
address = {Berlin},
pages = {15},
year = {2020},
abstract = {Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass index (BMI) when assessing all-cause mortality. We used data from 352,985 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) and Cox proportional hazards models adjusted for other risk factors. During a mean follow-up of 16.1 years, 38,178 participants died. Combining in one model BMI and a strongly correlated waist index altered the association patterns with mortality, to a predominantly negative association for BMI and a stronger positive association for the waist index, while combining BMI with the uncorrelated A Body Shape Index (ABSI) preserved the association patterns. Sex-specific cohort-wide quartiles of waist indices correlated with BMI could not separate high-risk from low-risk individuals within underweight (BMI<18.5 kg/m(2)) or obese (BMI30 kg/m(2)) categories, while the highest quartile of ABSI separated 18-39\% of the individuals within each BMI category, which had 22-55\% higher risk of death. In conclusion, only a waist index independent of BMI by design, such as ABSI, complements BMI and enables efficient risk stratification, which could facilitate personalisation of screening, treatment and monitoring.},
language = {en}
}
@article{ZouitaZouhalFerchichietal.2020,
author = {Zouita, Sghaier and Zouhal, Hassane and Ferchichi, Habiba and Paillard, Thierry and Dziri, Catherine and Hackney, Anthony C. and Laher, Ismail and Granacher, Urs and Ben Moussa Zouita, Amira},
title = {Effects of Combined Balance and Strength Training on Measures of Balance and Muscle Strength in Older Women With a History of Falls},
series = {Frontiers in Physiology},
volume = {11},
journal = {Frontiers in Physiology},
publisher = {Frontiers Research Foundation},
address = {Lausanne},
issn = {1664-042X},
doi = {10.3389/fphys.2020.619016},
pages = {13},
year = {2020},
abstract = {Objective: We investigated the effects of combined balance and strength training on measures of balance and muscle strength in older women with a history of falls. Methods: Twenty-seven older women aged 70.4 ± 4.1 years (age range: 65 to 75 years) were randomly allocated to either an intervention (IG, n = 12) or an active control (CG, n = 15) group. The IG completed 8 weeks combined balance and strength training program with three sessions per week including visual biofeedback using force plates. The CG received physical therapy and gait training at a rehabilitation center. Training volumes were similar between the groups. Pre and post training, tests were applied for the assessment of muscle strength (weight-bearing squat [WBS] by measuring the percentage of body mass borne by each leg at different knee flexions [0°, 30°, 60°, and 90°], sit-to-stand test [STS]), and balance. Balance tests used the modified clinical test of sensory interaction (mCTSIB) with eyes closed (EC) and opened (EO), on stable (firm) and unstable (foam) surfaces as well as spatial parameters of gait such as step width and length (cm) and walking speed (cm/s). Results: Significant group × time interactions were found for different degrees of knee flexion during WBS (0.0001 < p < 0.013, 0.441 < d < 0.762). Post hoc tests revealed significant pre-to-post improvements for both legs and for all degrees of flexion (0.0001 < p < 0.002, 0.697 < d < 1.875) for IG compared to CG. Significant group × time interactions were found for firm EO, foam EO, firm EC, and foam EC (0.006 < p < 0.029; 0.302 < d < 0.518). Post hoc tests showed significant pre-to-post improvements for both legs and for all degrees of oscillations (0.0001 < p < 0.004, 0.753 < d < 2.097) for IG compared to CG. This study indicates that combined balance and strength training improved percentage distribution of body weight between legs at different conditions of knee flexion (0°, 30°, 60°, and 90°) and also decreased the sway oscillation on a firm surface with eyes closed, and on foam surface (with eyes opened or closed) in the IG. Conclusion: The higher positive effects of training seen in standing balance tests, compared with dynamic tests, suggests that balance training exercises including lateral, forward, and backward exercises improved static balance to a greater extent in older women.},
language = {en}
}
@article{WiedmerJungCastroetal.2020,
author = {Wiedmer, Petra and Jung, Tobias and Castro, Jose Pedro and Pomatto, Laura C. D. and Sun, Patrick Y. and Davies, Kelvin J. A. and Grune, Tilman},
title = {Sarcopenia},
series = {Ageing research reviews : ARR},
volume = {65},
journal = {Ageing research reviews : ARR},
publisher = {Elsevier},
address = {Clare},
issn = {1568-1637},
doi = {10.1016/j.arr.2020.101200},
pages = {17},
year = {2020},
abstract = {Sarcopenia represents a muscle-wasting syndrome characterized by progressive and generalized degenerative loss of skeletal muscle mass, quality, and strength occurring during normal aging. Sarcopenia patients are mainly suffering from the loss in muscle strength and are faced with mobility disorders reducing their quality of life and are, therefore, at higher risk for morbidity (falls, bone fracture, metabolic diseases) and mortality.
Several molecular mechanisms have been described as causes for sarcopenia that refer to very different levels of muscle physiology. These mechanisms cover e. g. function of hormones (e. g. IGF-1 and Insulin), muscle fiber composition and neuromuscular drive, myo-satellite cell potential to differentiate and proliferate, inflammatory pathways as well as intracellular mechanisms in the processes of proteostasis and mitochondrial function.
In this review, we describe sarcopenia as a muscle-wasting syndrome distinct from other atrophic diseases and summarize the current view on molecular causes of sarcopenia development as well as open questions provoking further research efforts for establishing efficient lifestyle and therapeutic interventions.},
language = {en}
}
@article{RaveGranacherBoullosaetal.2020,
author = {Rav{\´e}, Guillaume and Granacher, Urs and Boullosa, Daniel and Hackney, Anthony C. and Zouhal, Hassane},
title = {How to Use Global Positioning Systems (GPS) Data to Monitor Training Load in the "Real World" of Elite Soccer},
series = {Frontiers in Physiology},
volume = {11},
journal = {Frontiers in Physiology},
publisher = {Frontiers Research Foundation},
address = {Lausanne},
issn = {1664-042X},
doi = {10.3389/fphys.2020.00944},
pages = {11},
year = {2020},
language = {en}
}
@article{AraziAsadiKhalkhalietal.2020,
author = {Arazi, Hamid and Asadi, Abbas and Khalkhali, Farhood and Boullosa, Daniel and Hackney, Anthony C. and Granacher, Urs and Zouhal, Hassane},
title = {Association Between the Acute to Chronic Workload Ratio and Injury Occurrence in Young Male Team Soccer Players},
volume = {11},
publisher = {Frontiers Research Foundation},
address = {Lausanne},
issn = {1664-042X},
doi = {10.3389/fphys.2020.00608},
pages = {7},
year = {2020},
abstract = {This study aimed to investigate the relationship between the acute to chronic workload ratio (ACWR), based upon participant session rating of perceived exertion (sRPE), using two models [(1) rolling averages (ACWRRA); and (2) exponentially weighted moving averages (ACWREWMA)] and the injury rate in young male team soccer players aged 17.1 ± 0.7 years during a competitive mesocycle. Twenty-two players were enrolled in this study and performed four training sessions per week with 2 days of recovery and 1 match day per week. During each training session and each weekly match, training time and sRPE were recorded. In addition, training impulse (TRIMP), monotony, and strain were subsequently calculated. The rate of injury was recorded for each soccer player over a period of 4 weeks (i.e., 28 days) using a daily questionnaire. The results showed that over the course of the study, the number of non-contact injuries was significantly higher than that for contact injuries (2.5 vs. 0.5, p = 0.01). There were also significant positive correlations between sRPE and training time (r = 0.411, p = 0.039), ACWRRA (r = 0.47, p = 0.049), and ACWREWMA (r = 0.51, p = 0.038). In addition, small-to-medium correlations were detected between ACWR and non-contact injury occurrence (ACWRRA, r = 0.31, p = 0.05; ACWREWMA, r = 0.53, p = 0.03). Explained variance (r²) for non-contact injury was significantly greater using the ACWREWMA model (ranging between 21 and 52\%) compared with ACWRRA (ranging between 17 and 39\%). In conclusion, the results of this study showed that the ACWREWMA model is more sensitive than ACWRRA to identify non-contact injury occurrence in male team soccer players during a short period in the competitive season.},
language = {en}
}
@misc{ChristakoudiTsilidisMulleretal.2020,
author = {Christakoudi, Sofa and Tsilidis, Konstantinos K. and Muller, David C. and Freisling, Heinz and Weiderpass, Elisabete and Overvad, Kim and S{\"o}derberg, Stefan and H{\"a}ggstr{\"o}m, Christel and Pischon, Tobias and Dahm, Christina C. and Zhang, Jie and Tj{\o}nneland, Anne and Schulze, Matthias Bernd},
title = {A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort},
series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
number = {1},
issn = {1866-8372},
doi = {10.25932/publishup-52582},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-525827},
pages = {17},
year = {2020},
abstract = {Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass index (BMI) when assessing all-cause mortality. We used data from 352,985 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) and Cox proportional hazards models adjusted for other risk factors. During a mean follow-up of 16.1 years, 38,178 participants died. Combining in one model BMI and a strongly correlated waist index altered the association patterns with mortality, to a predominantly negative association for BMI and a stronger positive association for the waist index, while combining BMI with the uncorrelated A Body Shape Index (ABSI) preserved the association patterns. Sex-specific cohort-wide quartiles of waist indices correlated with BMI could not separate high-risk from low-risk individuals within underweight (BMI<18.5 kg/m(2)) or obese (BMI30 kg/m(2)) categories, while the highest quartile of ABSI separated 18-39\% of the individuals within each BMI category, which had 22-55\% higher risk of death. In conclusion, only a waist index independent of BMI by design, such as ABSI, complements BMI and enables efficient risk stratification, which could facilitate personalisation of screening, treatment and monitoring.},
language = {en}
}
@article{ChristakoudiPagoniFerrarietal.2020,
author = {Christakoudi, Sofia and Pagoni, Panagiota and Ferrari, Pietro and Cross, Amanda J. and Tzoulaki, Ioanna and Muller, David C. and Weiderpass, Elisabete and Freisling, Heinz and Murphy, Neil and Dossus, Laure and Turzanski Fortner, Renee and Agudo, Antonio and Overvad, Kim and Perez-Cornago, Aurora and Key, Timothy J. and Brennan, Paul and Johansson, Mattias and Tjonneland, Anne and Halkjaer, Jytte and Boutron-Ruault, Marie-Christine and Artaud, Fanny and Severi, Gianluca and Kaaks, Rudolf and Schulze, Matthias Bernd and Bergmann, Manuela M. and Masala, Giovanna and Grioni, Sara and Simeon, Vittorio and Tumino, Rosario and Sacerdote, Carlotta and Skeie, Guri and Rylander, Charlotta and Borch, Kristin Benjaminsen and Quiros, J. Ramon and Rodriguez-Barranco, Miguel and Chirlaque, Maria-Dolores and Ardanaz, Eva and Amiano, Pilar and Drake, Isabel and Stocks, Tanja and H{\"a}ggstr{\"o}m, Christel and Harlid, Sophia and Ellingjord-Dale, Merete and Riboli, Elio and Tsilidis, Konstantinos K.},
title = {Weight change in middle adulthood and risk of cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort},
series = {International journal of cancer},
volume = {148},
journal = {International journal of cancer},
number = {7},
publisher = {Wiley},
address = {Hoboken},
issn = {0020-7136},
doi = {10.1002/ijc.33339},
pages = {1637 -- 1651},
year = {2020},
abstract = {Obesity is a risk factor for several major cancers. Associations of weight change in middle adulthood with cancer risk, however, are less clear. We examined the association of change in weight and body mass index (BMI) category during middle adulthood with 42 cancers, using multivariable Cox proportional hazards models in the European Prospective Investigation into Cancer and Nutrition cohort. Of 241 323 participants (31\% men), 20\% lost and 32\% gained weight (>0.4 to 5.0 kg/year) during 6.9 years (average). During 8.0 years of follow-up after the second weight assessment, 20 960 incident cancers were ascertained. Independent of baseline BMI, weight gain (per one kg/year increment) was positively associated with cancer of the corpus uteri (hazard ratio [HR] = 1.14; 95\% confidence interval: 1.05-1.23). Compared to stable weight (+/- 0.4 kg/year), weight gain (>0.4 to 5.0 kg/year) was positively associated with cancers of the gallbladder and bile ducts (HR = 1.41; 1.01-1.96), postmenopausal breast (HR = 1.08; 1.00-1.16) and thyroid (HR = 1.40; 1.04-1.90). Compared to maintaining normal weight, maintaining overweight or obese BMI (World Health Organisation categories) was positively associated with most obesity-related cancers. Compared to maintaining the baseline BMI category, weight gain to a higher BMI category was positively associated with cancers of the postmenopausal breast (HR = 1.19; 1.06-1.33), ovary (HR = 1.40; 1.04-1.91), corpus uteri (HR = 1.42; 1.06-1.91), kidney (HR = 1.80; 1.20-2.68) and pancreas in men (HR = 1.81; 1.11-2.95). Losing weight to a lower BMI category, however, was inversely associated with cancers of the corpus uteri (HR = 0.40; 0.23-0.69) and colon (HR = 0.69; 0.52-0.92). Our findings support avoiding weight gain and encouraging weight loss in middle adulthood.},
language = {en}
}
@misc{ChristakoudiPagoniFerrarietal.2020,
author = {Christakoudi, Sofia and Pagoni, Panagiota and Ferrari, Pietro and Cross, Amanda J. and Tzoulaki, Ioanna and Muller, David C. and Weiderpass, Elisabete and Freisling, Heinz and Murphy, Neil and Dossus, Laure and Turzanski Fortner, Renee and Agudo, Antonio and Overvad, Kim and Perez-Cornago, Aurora and Key, Timothy J. and Brennan, Paul and Johansson, Mattias and Tjonneland, Anne and Halkjaer, Jytte and Boutron-Ruault, Marie-Christine and Artaud, Fanny and Severi, Gianluca and Kaaks, Rudolf and Schulze, Matthias Bernd and Bergmann, Manuela M. and Masala, Giovanna and Grioni, Sara and Simeon, Vittorio and Tumino, Rosario and Sacerdote, Carlotta and Skeie, Guri and Rylander, Charlotta and Borch, Kristin Benjaminsen and Quiros, J. Ramon and Rodriguez-Barranco, Miguel and Chirlaque, Maria-Dolores and Ardanaz, Eva and Amiano, Pilar and Drake, Isabel and Stocks, Tanja and Haggstrom, Christel and Harlid, Sophia and Ellingjord-Dale, Merete and Riboli, Elio and Tsilidis, Konstantinos K.},
title = {Weight change in middle adulthood and risk of cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort},
series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
journal = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
number = {7},
issn = {1866-8372},
doi = {10.25932/publishup-57360},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-573609},
pages = {17},
year = {2020},
abstract = {Obesity is a risk factor for several major cancers. Associations of weight change in middle adulthood with cancer risk, however, are less clear. We examined the association of change in weight and body mass index (BMI) category during middle adulthood with 42 cancers, using multivariable Cox proportional hazards models in the European Prospective Investigation into Cancer and Nutrition cohort. Of 241 323 participants (31\% men), 20\% lost and 32\% gained weight (>0.4 to 5.0 kg/year) during 6.9 years (average). During 8.0 years of follow-up after the second weight assessment, 20 960 incident cancers were ascertained. Independent of baseline BMI, weight gain (per one kg/year increment) was positively associated with cancer of the corpus uteri (hazard ratio [HR] = 1.14; 95\% confidence interval: 1.05-1.23). Compared to stable weight (+/- 0.4 kg/year), weight gain (>0.4 to 5.0 kg/year) was positively associated with cancers of the gallbladder and bile ducts (HR = 1.41; 1.01-1.96), postmenopausal breast (HR = 1.08; 1.00-1.16) and thyroid (HR = 1.40; 1.04-1.90). Compared to maintaining normal weight, maintaining overweight or obese BMI (World Health Organisation categories) was positively associated with most obesity-related cancers. Compared to maintaining the baseline BMI category, weight gain to a higher BMI category was positively associated with cancers of the postmenopausal breast (HR = 1.19; 1.06-1.33), ovary (HR = 1.40; 1.04-1.91), corpus uteri (HR = 1.42; 1.06-1.91), kidney (HR = 1.80; 1.20-2.68) and pancreas in men (HR = 1.81; 1.11-2.95). Losing weight to a lower BMI category, however, was inversely associated with cancers of the corpus uteri (HR = 0.40; 0.23-0.69) and colon (HR = 0.69; 0.52-0.92). Our findings support avoiding weight gain and encouraging weight loss in middle adulthood.},
language = {en}
}
@misc{ZouitaZouhalFerchichietal.2020,
author = {Zouita, Sghaier and Zouhal, Hassane and Ferchichi, Habiba and Paillard, Thierry and Dziri, Catherine and Hackney, Anthony C. and Laher, Ismail and Granacher, Urs and Ben Moussa Zouita, Amira},
title = {Effects of Combined Balance and Strength Training on Measures of Balance and Muscle Strength in Older Women With a History of Falls},
series = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
number = {699},
issn = {1866-8364},
doi = {10.25932/publishup-49093},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-490932},
pages = {15},
year = {2020},
abstract = {Objective: We investigated the effects of combined balance and strength training on measures of balance and muscle strength in older women with a history of falls. Methods: Twenty-seven older women aged 70.4 ± 4.1 years (age range: 65 to 75 years) were randomly allocated to either an intervention (IG, n = 12) or an active control (CG, n = 15) group. The IG completed 8 weeks combined balance and strength training program with three sessions per week including visual biofeedback using force plates. The CG received physical therapy and gait training at a rehabilitation center. Training volumes were similar between the groups. Pre and post training, tests were applied for the assessment of muscle strength (weight-bearing squat [WBS] by measuring the percentage of body mass borne by each leg at different knee flexions [0°, 30°, 60°, and 90°], sit-to-stand test [STS]), and balance. Balance tests used the modified clinical test of sensory interaction (mCTSIB) with eyes closed (EC) and opened (EO), on stable (firm) and unstable (foam) surfaces as well as spatial parameters of gait such as step width and length (cm) and walking speed (cm/s). Results: Significant group × time interactions were found for different degrees of knee flexion during WBS (0.0001 < p < 0.013, 0.441 < d < 0.762). Post hoc tests revealed significant pre-to-post improvements for both legs and for all degrees of flexion (0.0001 < p < 0.002, 0.697 < d < 1.875) for IG compared to CG. Significant group × time interactions were found for firm EO, foam EO, firm EC, and foam EC (0.006 < p < 0.029; 0.302 < d < 0.518). Post hoc tests showed significant pre-to-post improvements for both legs and for all degrees of oscillations (0.0001 < p < 0.004, 0.753 < d < 2.097) for IG compared to CG. This study indicates that combined balance and strength training improved percentage distribution of body weight between legs at different conditions of knee flexion (0°, 30°, 60°, and 90°) and also decreased the sway oscillation on a firm surface with eyes closed, and on foam surface (with eyes opened or closed) in the IG. Conclusion: The higher positive effects of training seen in standing balance tests, compared with dynamic tests, suggests that balance training exercises including lateral, forward, and backward exercises improved static balance to a greater extent in older women.},
language = {en}
}
@misc{RaveGranacherBoullosaetal.2020,
author = {Rav{\´e}, Guillaume and Granacher, Urs and Boullosa, Daniel and Hackney, Anthony C. and Zouhal, Hassane},
title = {How to Use Global Positioning Systems (GPS) Data to Monitor Training Load in the "Real World" of Elite Soccer},
series = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
number = {663},
issn = {1866-8364},
doi = {10.25932/publishup-48055},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-480558},
pages = {13},
year = {2020},
language = {en}
}
@misc{AraziAsadiKhalkhalietal.2020,
author = {Arazi, Hamid and Asadi, Abbas and Khalkhali, Farhood and Boullosa, Daniel and Hackney, Anthony C. and Granacher, Urs and Zouhal, Hassane},
title = {Association Between the Acute to Chronic Workload Ratio and Injury Occurrence in Young Male Team Soccer Players},
series = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
number = {666},
issn = {1866-8364},
doi = {10.25932/publishup-48233},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-482330},
pages = {9},
year = {2020},
abstract = {This study aimed to investigate the relationship between the acute to chronic workload ratio (ACWR), based upon participant session rating of perceived exertion (sRPE), using two models [(1) rolling averages (ACWRRA); and (2) exponentially weighted moving averages (ACWREWMA)] and the injury rate in young male team soccer players aged 17.1 ± 0.7 years during a competitive mesocycle. Twenty-two players were enrolled in this study and performed four training sessions per week with 2 days of recovery and 1 match day per week. During each training session and each weekly match, training time and sRPE were recorded. In addition, training impulse (TRIMP), monotony, and strain were subsequently calculated. The rate of injury was recorded for each soccer player over a period of 4 weeks (i.e., 28 days) using a daily questionnaire. The results showed that over the course of the study, the number of non-contact injuries was significantly higher than that for contact injuries (2.5 vs. 0.5, p = 0.01). There were also significant positive correlations between sRPE and training time (r = 0.411, p = 0.039), ACWRRA (r = 0.47, p = 0.049), and ACWREWMA (r = 0.51, p = 0.038). In addition, small-to-medium correlations were detected between ACWR and non-contact injury occurrence (ACWRRA, r = 0.31, p = 0.05; ACWREWMA, r = 0.53, p = 0.03). Explained variance (r 2) for non-contact injury was significantly greater using the ACWREWMA model (ranging between 21 and 52\%) compared with ACWRRA (ranging between 17 and 39\%). In conclusion, the results of this study showed that the ACWREWMA model is more sensitive than ACWRRA to identify non-contact injury occurrence in male team soccer players during a short period in the competitive season.},
language = {en}
}
@misc{AraziAsadiKhalkhalietal.2020,
author = {Arazi, Hamid and Asadi, Abbas and Khalkhali, Farhood and Boullosa, Daniel and Hackney, Anthony C. and Granacher, Urs and Zouhal, Hassane},
title = {Association Between the Acute to Chronic Workload Ratio and Injury Occurrence in Young Male Team Soccer Players},
series = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
number = {644},
issn = {1866-8364},
doi = {10.25932/publishup-47296},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-472961},
pages = {9},
year = {2020},
abstract = {This study aimed to investigate the relationship between the acute to chronic workload ratio (ACWR), based upon participant session rating of perceived exertion (sRPE), using two models [(1) rolling averages (ACWRRA); and (2) exponentially weighted moving averages (ACWREWMA)] and the injury rate in young male team soccer players aged 17.1 ± 0.7 years during a competitive mesocycle. Twenty-two players were enrolled in this study and performed four training sessions per week with 2 days of recovery and 1 match day per week. During each training session and each weekly match, training time and sRPE were recorded. In addition, training impulse (TRIMP), monotony, and strain were subsequently calculated. The rate of injury was recorded for each soccer player over a period of 4 weeks (i.e., 28 days) using a daily questionnaire. The results showed that over the course of the study, the number of non-contact injuries was significantly higher than that for contact injuries (2.5 vs. 0.5, p = 0.01). There were also significant positive correlations between sRPE and training time (r = 0.411, p = 0.039), ACWRRA (r = 0.47, p = 0.049), and ACWREWMA (r = 0.51, p = 0.038). In addition, small-to-medium correlations were detected between ACWR and non-contact injury occurrence (ACWRRA, r = 0.31, p = 0.05; ACWREWMA, r = 0.53, p = 0.03). Explained variance (r²) for non-contact injury was significantly greater using the ACWREWMA model (ranging between 21 and 52\%) compared with ACWRRA (ranging between 17 and 39\%). In conclusion, the results of this study showed that the ACWREWMA model is more sensitive than ACWRRA to identify non-contact injury occurrence in male team soccer players during a short period in the competitive season.},
language = {en}
}
@article{SaidiBenAbderrahmanBoullosaetal.2020,
author = {Saidi, Karim and Ben Abderrahman, Abderraouf and Boullosa, Daniel and Dupont, Gr{\´e}gory and Hackney, Anthony C. and Bideau, Benoit and Pavillon, Thomas and Granacher, Urs and Zouhal, Hassane},
title = {The Interplay Between Plasma Hormonal Concentrations, Physical Fitness, Workload and Mood State Changes to Periods of Congested Match Play in Professional Soccer Players},
series = {Frontiers in Physiology},
volume = {11},
journal = {Frontiers in Physiology},
publisher = {Frontiers Research Foundation},
address = {Lausanne},
issn = {1664-042X},
doi = {10.3389/fphys.2020.00835},
pages = {14},
year = {2020},
abstract = {Background: The regular assessment of hormonal and mood state parameters in professional soccer are proposed as good indicators during periods of intense training and/or competition to avoid overtraining. Objective: The aim of this study was to analyze hormonal, psychological, workload and physical fitness parameters in elite soccer players in relation to changes in training and match exposure during a congested period of match play. Methods: Sixteen elite soccer players from a team playing in the first Tunisian soccer league were evaluated three times (T1, T2, and T3) over 12 weeks. The non-congested period of match play was from T1 to T2, when the players played 6 games over 6 weeks. The congested period was from T2 to T3, when the players played 10 games over 6 weeks. From T1 to T3, players performed the Yo-Yo intermittent recovery test level 1 (YYIR1), the repeated shuttle sprint ability test (RSSA), the countermovement jump test (CMJ), and the squat jump test (SJ). Plasma Cortisol (C), Testosterone (T), and the T/C ratio were analyzed at T1, T2, and T3. Players had their mood dimensions (tension, depression, anger, vigor, fatigue, confusion, and a Total Mood Disturbance) assessed through the Profile of Mood State questionnaire (POMS). Training session rating of perceived exertion (sRPE) was also recorded on a daily basis in order to quantify internal training load and elements of monotony and strain. Results: Significant performance declines (T1 < T2 < T3) were found for SJ performance (p = 0.04, effect size [ES] ES₁₋₂ = 0.15-0.06, ES₂₋₃ = 0.24) from T1 to T3. YYIR1 performance improved significantly from T1 to T2 and declined significantly from T2 to T3 (p = 0.001, ES₁₋₂ = 0.24, ES₂₋₃ = -2.54). Mean RSSA performance was significantly higher (p = 0.019, ES₁₋₂ = -0.47, ES₂₋₃ = 1.15) in T3 compared with T2 and T1. Best RSSA performance was significantly higher in T3 when compared with T2 and T1 (p = 0.006, ES₂₋₃ = 0.47, ES₁₋₂ = -0.56), but significantly lower in T2 when compared with to T1. T and T/C were significantly lower in T3 when compared with T2 and T1 (T: p = 0.03, ES₃₋₂ = -0.51, ES₃₋₁ = -0.51, T/C: p = 0.017, ES₃₋₂ = -1.1, ES₃₋₁ = -1.07). Significant decreases were found for the vigor scores in T3 when compared to T2 and T1 (p = 0.002, ES₁₋₂ = 0.31, ES₃₋₂ = -1.25). A significant increase was found in fatigue scores in T3 as compared to T1 and T2 (p = 0.002, ES₁₋₂ = 0.43, ES₂₋₃ = 0.81). A significant increase was found from T1 < T2 < T3 intension score (p = 0.002, ES₁₋₂ = 1.1, ES₂₋₃ = 0.2) and anger score (p = 0.03, ES₁₋₂ = 0.47, ES₂₋₃ = 0.33) over the study period. Total mood disturbance increased significantly (p = 0.02, ES₁₋₂ = 0.91, ES₂₋₃ = 1.1) from T1 to T3. Between T1-T2, significant relationships were observed between workload and changes in T (r = 0.66, p = 0.003), and T/C ratio (r = 0.62, p = 0.01). There were significant relationships between performance in RSSAbest and training load parameters (workload: r = 0.52, p = 0.03; monotony: r = 0.62, p = 0.01; strain: r = 0.62, p = 0.009). Between T2-T3, there was a significant relationship between Δ\% of total mood disturbance and Δ\% of YYIR1 (r = -0.54; p = 0.04), RSSAbest (r = 0.58, p = 0.01), SJ (r = -0,55, p = 0.01), T (r = 0.53; p = 0.03), and T/C (r = 0.5; p = 0.04). Conclusion: An intensive period of congested match play significantly compromised elite soccer players' physical and mental fitness. These changes were related to psychological but not hormonal parameters; even though significant alterations were detected for selected measures. Mood monitoring could be a simple and useful tool to determine the degree of preparedness for match play during a congested period in professional soccer.},
language = {en}
}
@misc{SaidiBenAbderrahmanBoullosaetal.2020,
author = {Saidi, Karim and Ben Abderrahman, Abderraouf and Boullosa, Daniel and Dupont, Gr{\´e}gory and Hackney, Anthony C. and Bideau, Benoit and Pavillon, Thomas and Granacher, Urs and Zouhal, Hassane},
title = {The Interplay Between Plasma Hormonal Concentrations, Physical Fitness, Workload and Mood State Changes to Periods of Congested Match Play in Professional Soccer Players},
series = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
number = {660},
issn = {1866-8364},
doi = {10.25932/publishup-47925},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-479259},
pages = {16},
year = {2020},
abstract = {Background: The regular assessment of hormonal and mood state parameters in professional soccer are proposed as good indicators during periods of intense training and/or competition to avoid overtraining. Objective: The aim of this study was to analyze hormonal, psychological, workload and physical fitness parameters in elite soccer players in relation to changes in training and match exposure during a congested period of match play. Methods: Sixteen elite soccer players from a team playing in the first Tunisian soccer league were evaluated three times (T1, T2, and T3) over 12 weeks. The non-congested period of match play was from T1 to T2, when the players played 6 games over 6 weeks. The congested period was from T2 to T3, when the players played 10 games over 6 weeks. From T1 to T3, players performed the Yo-Yo intermittent recovery test level 1 (YYIR1), the repeated shuttle sprint ability test (RSSA), the countermovement jump test (CMJ), and the squat jump test (SJ). Plasma Cortisol (C), Testosterone (T), and the T/C ratio were analyzed at T1, T2, and T3. Players had their mood dimensions (tension, depression, anger, vigor, fatigue, confusion, and a Total Mood Disturbance) assessed through the Profile of Mood State questionnaire (POMS). Training session rating of perceived exertion (sRPE) was also recorded on a daily basis in order to quantify internal training load and elements of monotony and strain. Results: Significant performance declines (T1 < T2 < T3) were found for SJ performance (p = 0.04, effect size [ES] ES₁₋₂ = 0.15-0.06, ES₂₋₃ = 0.24) from T1 to T3. YYIR1 performance improved significantly from T1 to T2 and declined significantly from T2 to T3 (p = 0.001, ES₁₋₂ = 0.24, ES₂₋₃ = -2.54). Mean RSSA performance was significantly higher (p = 0.019, ES₁₋₂ = -0.47, ES₂₋₃ = 1.15) in T3 compared with T2 and T1. Best RSSA performance was significantly higher in T3 when compared with T2 and T1 (p = 0.006, ES₂₋₃ = 0.47, ES₁₋₂ = -0.56), but significantly lower in T2 when compared with to T1. T and T/C were significantly lower in T3 when compared with T2 and T1 (T: p = 0.03, ES₃₋₂ = -0.51, ES₃₋₁ = -0.51, T/C: p = 0.017, ES₃₋₂ = -1.1, ES₃₋₁ = -1.07). Significant decreases were found for the vigor scores in T3 when compared to T2 and T1 (p = 0.002, ES₁₋₂ = 0.31, ES₃₋₂ = -1.25). A significant increase was found in fatigue scores in T3 as compared to T1 and T2 (p = 0.002, ES₁₋₂ = 0.43, ES₂₋₃ = 0.81). A significant increase was found from T1 < T2 < T3 intension score (p = 0.002, ES₁₋₂ = 1.1, ES₂₋₃ = 0.2) and anger score (p = 0.03, ES₁₋₂ = 0.47, ES₂₋₃ = 0.33) over the study period. Total mood disturbance increased significantly (p = 0.02, ES₁₋₂ = 0.91, ES₂₋₃ = 1.1) from T1 to T3. Between T1-T2, significant relationships were observed between workload and changes in T (r = 0.66, p = 0.003), and T/C ratio (r = 0.62, p = 0.01). There were significant relationships between performance in RSSAbest and training load parameters (workload: r = 0.52, p = 0.03; monotony: r = 0.62, p = 0.01; strain: r = 0.62, p = 0.009). Between T2-T3, there was a significant relationship between Δ\% of total mood disturbance and Δ\% of YYIR1 (r = -0.54; p = 0.04), RSSAbest (r = 0.58, p = 0.01), SJ (r = -0,55, p = 0.01), T (r = 0.53; p = 0.03), and T/C (r = 0.5; p = 0.04). Conclusion: An intensive period of congested match play significantly compromised elite soccer players' physical and mental fitness. These changes were related to psychological but not hormonal parameters; even though significant alterations were detected for selected measures. Mood monitoring could be a simple and useful tool to determine the degree of preparedness for match play during a congested period in professional soccer.},
language = {en}
}
@misc{PavillonTournyBenAbderrahmanetal.2020,
author = {Pavillon, Thomas and Tourny, Claire and Ben Abderrahman, Abderraouf and Salhi, Iyed and Zouita, Sghaeir and Rouissi, Mehdi and Hackney, Anthony C. and Granacher, Urs and Zouhal, Hassane},
title = {Sprint and jump performances in highly trained young soccer players of different chronological age},
series = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
number = {697},
issn = {1866-8364},
doi = {10.25932/publishup-49055},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-490557},
pages = {12},
year = {2020},
abstract = {Objective The aim of this study was to examine the effects of two different sprint-training regimes on sprint and jump performances according to age in elite young male soccer players over the course of one soccer season. Methods Players were randomly assigned to two training groups. Group 1 performed systematic change-of-direction sprints (CODST, U19 [n = 9], U17 [n = 9], U15 [n = 10]) while group 2 conducted systematic linear sprints (LST, U19 [n = 9], U17 [n = 9], U15 [n = 9]). Training volumes were similar between groups (40 sprints per week x 30 weeks = 1200 sprints per season). Pre and post training, all players performed tests for the assessment of linear and slalom sprint speed (5-m and 10-m), countermovement jump, and maximal aerobic speed performance. Results For all physical fitness measures, the baseline-adjusted means data (ANCOVA) across the age groups showed no significant differences between LST and CODST at post (0.061 < p < 0.995; 0.0017 < d < 1.01). The analyses of baseline-adjusted means for all physical fitness measures for U15, U17, and U19 (LST vs. CODST) revealed no significant differences between LST and CODST for U15 (0.213 < p < 0.917; 0.001 < d < 0.087), U17 (0.132 < p < 0.976; 0.001 < d < 0.310), and U19 (0.300 < p < 0.999; 0.001 < d < 0.049) at post. Conclusions The results from this study showed that both, LST and CODST induced significant changes in the sprint, lower limbs power, and aerobic performances in young elite soccer players. Since no significant differences were observed between LST and CODST, the observed changes are most likely due to training and/or maturation. Therefore, more research is needed to elucidate whether CODST, LST or a combination of both is beneficial for youth soccer athletes' performance development.},
language = {en}
}
@article{PavillonTournyBenAbderrahmanetal.2020,
author = {Pavillon, Thomas and Tourny, Claire and Ben Abderrahman, Abderraouf and Salhi, Iyed and Zouita, Sghaeir and Rouissi, Mehdi and Hackney, Anthony C. and Granacher, Urs and Zouhal, Hassane},
title = {Sprint and jump performances in highly trained young soccer players of different chronological age},
series = {Journal of Exercise Science \& Fitness},
volume = {19},
journal = {Journal of Exercise Science \& Fitness},
number = {2},
publisher = {Elsevier},
address = {Singapore},
issn = {1728-869x},
doi = {10.1016/j.jesf.2020.10.003},
pages = {81 -- 90},
year = {2020},
abstract = {Objective The aim of this study was to examine the effects of two different sprint-training regimes on sprint and jump performances according to age in elite young male soccer players over the course of one soccer season. Methods Players were randomly assigned to two training groups. Group 1 performed systematic change-of-direction sprints (CODST, U19 [n = 9], U17 [n = 9], U15 [n = 10]) while group 2 conducted systematic linear sprints (LST, U19 [n = 9], U17 [n = 9], U15 [n = 9]). Training volumes were similar between groups (40 sprints per week x 30 weeks = 1200 sprints per season). Pre and post training, all players performed tests for the assessment of linear and slalom sprint speed (5-m and 10-m), countermovement jump, and maximal aerobic speed performance. Results For all physical fitness measures, the baseline-adjusted means data (ANCOVA) across the age groups showed no significant differences between LST and CODST at post (0.061 < p < 0.995; 0.0017 < d < 1.01). The analyses of baseline-adjusted means for all physical fitness measures for U15, U17, and U19 (LST vs. CODST) revealed no significant differences between LST and CODST for U15 (0.213 < p < 0.917; 0.001 < d < 0.087), U17 (0.132 < p < 0.976; 0.001 < d < 0.310), and U19 (0.300 < p < 0.999; 0.001 < d < 0.049) at post. Conclusions The results from this study showed that both, LST and CODST induced significant changes in the sprint, lower limbs power, and aerobic performances in young elite soccer players. Since no significant differences were observed between LST and CODST, the observed changes are most likely due to training and/or maturation. Therefore, more research is needed to elucidate whether CODST, LST or a combination of both is beneficial for youth soccer athletes' performance development.},
language = {en}
}
@article{SmirnovKronbergDalyetal.2020,
author = {Smirnov, Artem G. and Kronberg, Elena A. and Daly, Patrick W. and Aseev, Nikita and Shprits, Yuri and Kellerman, Adam C.},
title = {Adiabatic Invariants Calculations for Cluster Mission: A Long-Term Product for Radiation Belts Studies},
series = {Journal of Geophysical Research: Space Physics},
volume = {125},
journal = {Journal of Geophysical Research: Space Physics},
number = {2},
publisher = {John Wiley \& Sons, Inc.},
address = {New Jersey},
pages = {12},
year = {2020},
abstract = {The Cluster mission has produced a large data set of electron flux measurements in the Earth's magnetosphere since its launch in late 2000. Electron fluxes are measured using Research with Adaptive Particle Imaging Detector (RAPID)/Imaging Electron Spectrometer (IES) detector as a function of energy, pitch angle, spacecraft position, and time. However, no adiabatic invariants have been calculated for Cluster so far. In this paper we present a step-by-step guide to calculations of adiabatic invariants and conversion of the electron flux to phase space density (PSD) in these coordinates. The electron flux is measured in two RAPID/IES energy channels providing pitch angle distribution at energies 39.2-50.5 and 68.1-94.5 keV in nominal mode since 2004. A fitting method allows to expand the conversion of the differential fluxes to the range from 40 to 150 keV. Best data coverage for phase space density in adiabatic invariant coordinates can be obtained for values of second adiabatic invariant, K, similar to 10(2), and values of the first adiabatic invariant mu in the range approximate to 5-20 MeV/G. Furthermore, we describe the production of a new data product "LSTAR," equivalent to the third adiabatic invariant, available through the Cluster Science Archive for years 2001-2018 with 1-min resolution. The produced data set adds to the availability of observations in Earth's radiation belts region and can be used for long-term statistical purposes.},
language = {en}
}
@misc{SmirnovKronbergDalyetal.2020,
author = {Smirnov, Artem G. and Kronberg, Elena A. and Daly, Patrick W. and Aseev, Nikita and Shprits, Yuri and Kellerman, Adam C.},
title = {Adiabatic Invariants Calculations for Cluster Mission: A Long-Term Product for Radiation Belts Studies},
series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
number = {2},
issn = {1866-8372},
doi = {10.25932/publishup-52391},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-523915},
pages = {14},
year = {2020},
abstract = {The Cluster mission has produced a large data set of electron flux measurements in the Earth's magnetosphere since its launch in late 2000. Electron fluxes are measured using Research with Adaptive Particle Imaging Detector (RAPID)/Imaging Electron Spectrometer (IES) detector as a function of energy, pitch angle, spacecraft position, and time. However, no adiabatic invariants have been calculated for Cluster so far. In this paper we present a step-by-step guide to calculations of adiabatic invariants and conversion of the electron flux to phase space density (PSD) in these coordinates. The electron flux is measured in two RAPID/IES energy channels providing pitch angle distribution at energies 39.2-50.5 and 68.1-94.5 keV in nominal mode since 2004. A fitting method allows to expand the conversion of the differential fluxes to the range from 40 to 150 keV. Best data coverage for phase space density in adiabatic invariant coordinates can be obtained for values of second adiabatic invariant, K, similar to 10(2), and values of the first adiabatic invariant mu in the range approximate to 5-20 MeV/G. Furthermore, we describe the production of a new data product "LSTAR," equivalent to the third adiabatic invariant, available through the Cluster Science Archive for years 2001-2018 with 1-min resolution. The produced data set adds to the availability of observations in Earth's radiation belts region and can be used for long-term statistical purposes.},
language = {en}
}
@article{JiangTaoStolterfohtetal.2020,
author = {Jiang, Wei and Tao, Chen and Stolterfoht, Martin and Jin, Hui and Stephen, Meera and Lin, Qianqian and Nagiri, Ravi C. R. and Burn, Paul L. and Gentle, Ian R.},
title = {Hole-transporting materials for low donor content organic solar cells},
series = {Organic electronics : physics, materials and applications},
volume = {76},
journal = {Organic electronics : physics, materials and applications},
publisher = {Elsevier},
address = {Amsterdam},
issn = {1566-1199},
doi = {10.1016/j.orgel.2019.105480},
pages = {7},
year = {2020},
abstract = {Low donor content solar cells are an intriguing class of photovoltaic device about which there is still considerable discussion with respect to their mode of operation. We have synthesized a series of triphenylamine-based materials for use in low donor content devices with the electron accepting [6,6]-phenyl-C71-butyric acid methyl ester (PC(7)0BM). The triphenylamine-based materials absorb light in the near UV enabling the PC(7)0BM to be be the main light absorbing organic semiconducting material in the solar cell. It was found that the devices did not operate as classical Schottky junctions but rather photocurrent was generated by hole transfer from the photo-excited PC(7)0BM to the triphenylamine-based donors. We found that replacing the methoxy surface groups with methyl groups on the donor material led to a decrease in hole mobility for the neat films, which was due to the methyl substituted materials having the propensity to aggregate. The thermodynamic drive to aggregate was advantageous for the performance of the low donor content (6 wt\%) films. It was found that the 6 wt\% donor devices generally gave higher performance than devices containing 50 wt\% of the donor.},
language = {en}
}
@misc{SchulzeBettBivouretal.2020,
author = {Schulze, Patricia S. C. and Bett, Alexander J. and Bivour, Martin and Caprioglio, Pietro and Gerspacher, Fabian M. and Kabakl{\i}, {\"O}zde Ş. and Richter, Armin and Stolterfoht, Martin and Zhang, Qinxin and Neher, Dieter and Hermle, Martin and Hillebrecht, Harald and Glunz, Stefan W. and Goldschmidt, Jan Christoph},
title = {25.1\% high-efficiency monolithic perovskite silicon tandem solar cell with a high bandgap perovskite absorber},
series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
number = {7},
issn = {1866-8372},
doi = {10.25932/publishup-52566},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-525668},
pages = {12},
year = {2020},
abstract = {Monolithic perovskite silicon tandem solar cells can overcome the theoretical efficiency limit of silicon solar cells. This requires an optimum bandgap, high quantum efficiency, and high stability of the perovskite. Herein, a silicon heterojunction bottom cell is combined with a perovskite top cell, with an optimum bandgap of 1.68 eV in planar p-i-n tandem configuration. A methylammonium-free FA(0.75)Cs(0.25)Pb(I0.8Br0.2)(3) perovskite with high Cs content is investigated for improved stability. A 10\% molarity increase to 1.1 m of the perovskite precursor solution results in approximate to 75 nm thicker absorber layers and 0.7 mA cm(-2) higher short-circuit current density. With the optimized absorber, tandem devices reach a high fill factor of 80\% and up to 25.1\% certified efficiency. The unencapsulated tandem device shows an efficiency improvement of 2.3\% (absolute) over 5 months, showing the robustness of the absorber against degradation. Moreover, a photoluminescence quantum yield analysis reveals that with adapted charge transport materials and surface passivation, along with improved antireflection measures, the high bandgap perovskite absorber has the potential for 30\% tandem efficiency in the near future.},
language = {en}
}
@article{SchulzeBettBivouretal.2020,
author = {Schulze, Patricia S. C. and Bett, Alexander J. and Bivour, Martin and Caprioglio, Pietro and Gerspacher, Fabian M. and Kabakl{\i}, {\"O}zde Ş. and Richter, Armin and Stolterfoht, Martin and Zhang, Qinxin and Neher, Dieter and Hermle, Martin and Hillebrecht, Harald and Glunz, Stefan W. and Goldschmidt, Jan Christoph},
title = {25.1\% high-efficiency monolithic perovskite silicon tandem solar cell with a high bandgap perovskite absorber},
series = {Solar RRL},
volume = {4},
journal = {Solar RRL},
number = {7},
publisher = {John Wiley \& Sons, Inc.},
address = {New Jersey},
pages = {10},
year = {2020},
abstract = {Monolithic perovskite silicon tandem solar cells can overcome the theoretical efficiency limit of silicon solar cells. This requires an optimum bandgap, high quantum efficiency, and high stability of the perovskite. Herein, a silicon heterojunction bottom cell is combined with a perovskite top cell, with an optimum bandgap of 1.68 eV in planar p-i-n tandem configuration. A methylammonium-free FA(0.75)Cs(0.25)Pb(I0.8Br0.2)(3) perovskite with high Cs content is investigated for improved stability. A 10\% molarity increase to 1.1 m of the perovskite precursor solution results in approximate to 75 nm thicker absorber layers and 0.7 mA cm(-2) higher short-circuit current density. With the optimized absorber, tandem devices reach a high fill factor of 80\% and up to 25.1\% certified efficiency. The unencapsulated tandem device shows an efficiency improvement of 2.3\% (absolute) over 5 months, showing the robustness of the absorber against degradation. Moreover, a photoluminescence quantum yield analysis reveals that with adapted charge transport materials and surface passivation, along with improved antireflection measures, the high bandgap perovskite absorber has the potential for 30\% tandem efficiency in the near future.},
language = {en}
}
@article{SeroussiNowickiPayneetal.2020,
author = {Seroussi, Helene and Nowicki, Sophie and Payne, Antony J. and Goelzer, Heiko and Lipscomb, William H. and Abe-Ouchi, Ayako and Agosta, Cecile and Albrecht, Torsten and Asay-Davis, Xylar and Barthel, Alice and Calov, Reinhard and Cullather, Richard and Dumas, Christophe and Galton-Fenzi, Benjamin K. and Gladstone, Rupert and Golledge, Nicholas R. and Gregory, Jonathan M. and Greve, Ralf and Hattermann, Tore and Hoffman, Matthew J. and Humbert, Angelika and Huybrechts, Philippe and Jourdain, Nicolas C. and Kleiner, Thomas and Larour, Eric and Leguy, Gunter R. and Lowry, Daniel P. and Little, Chistopher M. and Morlighem, Mathieu and Pattyn, Frank and Pelle, Tyler and Price, Stephen F. and Quiquet, Aurelien and Reese, Ronja and Schlegel, Nicole-Jeanne and Shepherd, Andrew and Simon, Erika and Smith, Robin S. and Straneo, Fiammetta and Sun, Sainan and Trusel, Luke D. and Van Breedam, Jonas and van de Wal, Roderik S. W. and Winkelmann, Ricarda and Zhao, Chen and Zhang, Tong and Zwinger, Thomas},
title = {ISMIP6 Antarctica},
series = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
volume = {14},
journal = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
number = {9},
publisher = {Copernicus},
address = {G{\"o}ttingen},
issn = {1994-0416},
doi = {10.5194/tc-14-3033-2020},
pages = {3033 -- 3070},
year = {2020},
abstract = {Ice flow models of the Antarctic ice sheet are commonly used to simulate its future evolution in response to different climate scenarios and assess the mass loss that would contribute to future sea level rise. However, there is currently no consensus on estimates of the future mass balance of the ice sheet, primarily because of differences in the representation of physical processes, forcings employed and initial states of ice sheet models. This study presents results from ice flow model simulations from 13 international groups focusing on the evolution of the Antarctic ice sheet during the period 2015-2100 as part of the Ice Sheet Model Intercomparison for CMIP6 (ISMIP6). They are forced with outputs from a subset of models from the Coupled Model Intercomparison Project Phase 5 (CMIP5), representative of the spread in climate model results. Simulations of the Antarctic ice sheet contribution to sea level rise in response to increased warming during this period varies between 7:8 and 30.0 cm of sea level equivalent (SLE) under Representative Concentration Pathway (RCP) 8.5 scenario forcing. These numbers are relative to a control experiment with constant climate conditions and should therefore be added to the mass loss contribution under climate conditions similar to present-day conditions over the same period. The simulated evolution of the West Antarctic ice sheet varies widely among models, with an overall mass loss, up to 18.0 cm SLE, in response to changes in oceanic conditions. East Antarctica mass change varies between 6 :1 and 8.3 cm SLE in the simulations, with a significant increase in surface mass balance outweighing the increased ice discharge under most RCP 8.5 scenario forcings. The inclusion of ice shelf collapse, here assumed to be caused by large amounts of liquid water ponding at the surface of ice shelves, yields an additional simulated mass loss of 28mm compared to simulations without ice shelf collapse. The largest sources of uncertainty come from the climate forcing, the ocean-induced melt rates, the calibration of these melt rates based on oceanic conditions taken outside of ice shelf cavities and the ice sheet dynamic response to these oceanic changes. Results under RCP 2.6 scenario based on two CMIP5 climate models show an additional mass loss of 0 and 3 cm of SLE on average compared to simulations done under present-day conditions for the two CMIP5 forcings used and display limited mass gain in East Antarctica.},
language = {en}
}
@misc{GorskiJungLietal.2020,
author = {Gorski, Mathias and Jung, Bettina and Li, Yong and Matias-Garcia, Pamela R. and Wuttke, Matthias and Coassin, Stefan and Thio, Chris H. L. and Kleber, Marcus E. and Winkler, Thomas W. and Wanner, Veronika and Chai, Jin-Fang and Chu, Audrey Y. and Cocca, Massimiliano and Feitosa, Mary F. and Ghasemi, Sahar and Hoppmann, Anselm and Horn, Katrin and Li, Man and Nutile, Teresa and Scholz, Markus and Sieber, Karsten B. and Teumer, Alexander and Tin, Adrienne and Wang, Judy and Tayo, Bamidele O. and Ahluwalia, Tarunveer S. and Almgren, Peter and Bakker, Stephan J. L. and Banas, Bernhard and Bansal, Nisha and Biggs, Mary L. and Boerwinkle, Eric and B{\"o}ttinger, Erwin and Brenner, Hermann and Carroll, Robert J. and Chalmers, John and Chee, Miao-Li and Chee, Miao-Ling and Cheng, Ching-Yu and Coresh, Josef and de Borst, Martin H. and Degenhardt, Frauke and Eckardt, Kai-Uwe and Endlich, Karlhans and Franke, Andre and Freitag-Wolf, Sandra and Gampawar, Piyush and Gansevoort, Ron T. and Ghanbari, Mohsen and Gieger, Christian and Hamet, Pavel and Ho, Kevin and Hofer, Edith and Holleczek, Bernd and Foo, Valencia Hui Xian and Hutri-Kahonen, Nina and Hwang, Shih-Jen and Ikram, M. Arfan and Josyula, Navya Shilpa and Kahonen, Mika and Khor, Chiea-Chuen and Koenig, Wolfgang and Kramer, Holly and Kraemer, Bernhard K. and Kuehnel, Brigitte and Lange, Leslie A. and Lehtimaki, Terho and Lieb, Wolfgang and Loos, Ruth J. F. and Lukas, Mary Ann and Lyytikainen, Leo-Pekka and Meisinger, Christa and Meitinger, Thomas and Melander, Olle and Milaneschi, Yuri and Mishra, Pashupati P. and Mononen, Nina and Mychaleckyj, Josyf C. and Nadkarni, Girish N. and Nauck, Matthias and Nikus, Kjell and Ning, Boting and Nolte, Ilja M. and O'Donoghue, Michelle L. and Orho-Melander, Marju and Pendergrass, Sarah A. and Penninx, Brenda W. J. H. and Preuss, Michael H. and Psaty, Bruce M. and Raffield, Laura M. and Raitakari, Olli T. and Rettig, Rainer and Rheinberger, Myriam and Rice, Kenneth M. and Rosenkranz, Alexander R. and Rossing, Peter and Rotter, Jerome and Sabanayagam, Charumathi and Schmidt, Helena and Schmidt, Reinhold and Schoettker, Ben and Schulz, Christina-Alexandra and Sedaghat, Sanaz and Shaffer, Christian M. and Strauch, Konstantin and Szymczak, Silke and Taylor, Kent D. and Tremblay, Johanne and Chaker, Layal and van der Harst, Pim and van der Most, Peter J. and Verweij, Niek and Voelker, Uwe and Waldenberger, Melanie and Wallentin, Lars and Waterworth, Dawn M. and White, Harvey D. and Wilson, James G. and Wong, Tien-Yin and Woodward, Mark and Yang, Qiong and Yasuda, Masayuki and Yerges-Armstrong, Laura M. and Zhang, Yan and Snieder, Harold and Wanner, Christoph and Boger, Carsten A. and Kottgen, Anna and Kronenberg, Florian and Pattaro, Cristian and Heid, Iris M.},
title = {Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline},
series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Reihe der Digital Engineering Fakult{\"a}t},
journal = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Reihe der Digital Engineering Fakult{\"a}t},
number = {19},
doi = {10.25932/publishup-56537},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-565379},
pages = {14},
year = {2020},
abstract = {Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25\% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95\% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function.},
language = {en}
}
@article{RothwellMurphyAleksandrovaetal.2020,
author = {Rothwell, Joseph A. and Murphy, Neil and Aleksandrova, Krasimira and Schulze, Matthias Bernd and Bešević, Jelena and Kliemann, Nathalie and Jenab, Mazda and Ferrari, Pietro and Achaintre, David and Gicquiau, Audrey and Vozar, B{\´e}atrice and Scalbert, Augustin and Huybrechts, Inge and Freisling, Heinz and Prehn, Cornelia and Adamski, Jerzy and Cross, Amanda J. and Pala, Valeria Maria and Boutron-Ruault, Marie-Christine and Dahm, Christina C. and Overvad, Kim and Gram, Inger Torhild and Sandanger, Torkjel M. and Skeie, Guri and Jakszyn, Paula and Tsilidis, Kostas K. and Hughes, David J. and van Guelpen, Bethany and Bod{\´e}n, Stina and S{\´a}nchez, Maria-Jos{\´e} and Schmidt, Julie A. and Katzke, Verena and K{\"u}hn, Tilman and Colorado-Yohar, Sandra and Tumino, Rosario and Bueno-de-Mesquita, Bas and Vineis, Paolo and Masala, Giovanna and Panico, Salvatore and Eriksen, Anne Kirstine and Tj{\o}nneland, Anne and Aune, Dagfinn and Weiderpass, Elisabete and Severi, Gianluca and Chaj{\`e}s, V{\´e}ronique and Gunter, Marc J.},
title = {Metabolic signatures of healthy lifestyle patterns and colorectal cancer risk in a European cohort},
series = {Clinical gastroenterology and hepatology},
volume = {20},
journal = {Clinical gastroenterology and hepatology},
publisher = {Elsevier},
address = {New York, NY},
issn = {1542-3565},
doi = {10.1016/j.cgh.2020.11.045},
pages = {E1061 -- E1082},
year = {2020},
abstract = {BACKGROUND \& AIMS: Colorectal cancer risk can be lowered by adherence to the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) guidelines. We derived metabolic signatures of adherence to these guidelines and tested their associations with colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort. METHODS: Scores reflecting adherence to the WCRF/AICR recommendations (scale, 1-5) were calculated from participant data on weight maintenance, physical activity, diet, and alcohol among a discovery set of 5738 cancer-free European Prospective Investigation into Cancer and Nutrition participants with metabolomics data. Partial least-squares regression was used to derive fatty acid and endogenous metabolite signatures of the WCRF/AICR score in this group. In an independent set of 1608 colorectal cancer cases and matched controls, odds ratios (ORs) and 95\% CIs were calculated for colorectal cancer risk per unit increase in WCRF/AICR score and per the corresponding change in metabolic signatures using multivariable conditional logistic regression. RESULTS: Higher WCRF/AICR scores were characterized by metabolic signatures of increased odd-chain fatty acids, serine, glycine, and specific phosphatidylcholines. Signatures were inversely associated more strongly with colorectal cancer risk (fatty acids: OR, 0.51 per unit increase; 95\% CI, 0.29-0.90; endogenous metabolites: OR, 0.62 per unit change; 95\% CI, 0.50-0.78) than the WCRF/AICR score (OR, 0.93 per unit change; 95\% CI, 0.86-1.00) overall. Signature associations were stronger in male compared with female participants. CONCLUSIONS: Metabolite profiles reflecting adherence to WCRF/AICR guidelines and additional lifestyle or biological risk factors were associated with colorectal cancer. Measuring a specific panel of metabolites representative of a healthy or unhealthy lifestyle may identify strata of the population at higher risk of colorectal cancer.},
language = {en}
}
@misc{BarboliniWoutersenDupontNivetetal.2020,
author = {Barbolini, Natasha and Woutersen, Amber and Dupont-Nivet, Guillaume and Silvestro, Daniele and Tardif-Becquet, Delphine and Coster, Pauline M. C. and Meijer, Niels and Chang, Cun and Zhang, Hou-Xi and Licht, Alexis and Rydin, Catarina and Koutsodendris, Andreas and Han, Fang and Rohrmann, Alexander and Liu, Xiang-Jun and Zhang, Y. and Donnadieu, Yannick and Fluteau, Frederic and Ladant, Jean-Baptiste and Le Hir, Guillaume and Hoorn, M. Carina},
title = {Cenozoic evolution of the steppe-desert biome in Central Asia},
series = {Science Advances},
volume = {6},
journal = {Science Advances},
number = {41},
publisher = {American Association for the Advancement of Science},
address = {Washington},
issn = {2375-2548},
doi = {10.1126/sciadv.abb8227},
pages = {16},
year = {2020},
abstract = {The origins and development of the arid and highly seasonal steppe-desert biome in Central Asia, the largest of its kind in the world, remain largely unconstrained by existing records. It is unclear how Cenozoic climatic, geological, and biological forces, acting at diverse spatial and temporal scales, shaped Central Asian ecosystems through time. Our synthesis shows that the Central Asian steppe-desert has existed since at least Eocene times but experienced no less than two regime shifts, one at the Eocene-Oligocene Transition and one in the mid-Miocene. These shifts separated three successive "stable states," each characterized by unique floral and faunal structures. Past responses to disturbance in the Asian steppe-desert imply that modern ecosystems are unlikely to recover their present structures and diversity if forced into a new regime. This is of concern for Asian steppes today, which are being modified for human use and lost to desertification at unprecedented rates.},
language = {en}
}
@article{VaidSomaniRussaketal.2020,
author = {Vaid, Akhil and Somani, Sulaiman and Russak, Adam J. and De Freitas, Jessica K. and Chaudhry, Fayzan F. and Paranjpe, Ishan and Johnson, Kipp W. and Lee, Samuel J. and Miotto, Riccardo and Richter, Felix and Zhao, Shan and Beckmann, Noam D. and Naik, Nidhi and Kia, Arash and Timsina, Prem and Lala, Anuradha and Paranjpe, Manish and Golden, Eddye and Danieletto, Matteo and Singh, Manbir and Meyer, Dara and O'Reilly, Paul F. and Huckins, Laura and Kovatch, Patricia and Finkelstein, Joseph and Freeman, Robert M. and Argulian, Edgar and Kasarskis, Andrew and Percha, Bethany and Aberg, Judith A. and Bagiella, Emilia and Horowitz, Carol R. and Murphy, Barbara and Nestler, Eric J. and Schadt, Eric E. and Cho, Judy H. and Cordon-Cardo, Carlos and Fuster, Valentin and Charney, Dennis S. and Reich, David L. and B{\"o}ttinger, Erwin and Levin, Matthew A. and Narula, Jagat and Fayad, Zahi A. and Just, Allan C. and Charney, Alexander W. and Nadkarni, Girish N. and Glicksberg, Benjamin S.},
title = {Machine learning to predict mortality and critical events in a cohort of patients with COVID-19 in New York City: model development and validation},
series = {Journal of medical internet research : international scientific journal for medical research, information and communication on the internet ; JMIR},
volume = {22},
journal = {Journal of medical internet research : international scientific journal for medical research, information and communication on the internet ; JMIR},
number = {11},
publisher = {Healthcare World},
address = {Richmond, Va.},
issn = {1439-4456},
doi = {10.2196/24018},
pages = {19},
year = {2020},
abstract = {Background: COVID-19 has infected millions of people worldwide and is responsible for several hundred thousand fatalities. The COVID-19 pandemic has necessitated thoughtful resource allocation and early identification of high-risk patients. However, effective methods to meet these needs are lacking. Objective: The aims of this study were to analyze the electronic health records (EHRs) of patients who tested positive for COVID-19 and were admitted to hospitals in the Mount Sinai Health System in New York City; to develop machine learning models for making predictions about the hospital course of the patients over clinically meaningful time horizons based on patient characteristics at admission; and to assess the performance of these models at multiple hospitals and time points. Methods: We used Extreme Gradient Boosting (XGBoost) and baseline comparator models to predict in-hospital mortality and critical events at time windows of 3, 5, 7, and 10 days from admission. Our study population included harmonized EHR data from five hospitals in New York City for 4098 COVID-19-positive patients admitted from March 15 to May 22, 2020. The models were first trained on patients from a single hospital (n=1514) before or on May 1, externally validated on patients from four other hospitals (n=2201) before or on May 1, and prospectively validated on all patients after May 1 (n=383). Finally, we established model interpretability to identify and rank variables that drive model predictions. Results: Upon cross-validation, the XGBoost classifier outperformed baseline models, with an area under the receiver operating characteristic curve (AUC-ROC) for mortality of 0.89 at 3 days, 0.85 at 5 and 7 days, and 0.84 at 10 days. XGBoost also performed well for critical event prediction, with an AUC-ROC of 0.80 at 3 days, 0.79 at 5 days, 0.80 at 7 days, and 0.81 at 10 days. In external validation, XGBoost achieved an AUC-ROC of 0.88 at 3 days, 0.86 at 5 days, 0.86 at 7 days, and 0.84 at 10 days for mortality prediction. Similarly, the unimputed XGBoost model achieved an AUC-ROC of 0.78 at 3 days, 0.79 at 5 days, 0.80 at 7 days, and 0.81 at 10 days. Trends in performance on prospective validation sets were similar. At 7 days, acute kidney injury on admission, elevated LDH, tachypnea, and hyperglycemia were the strongest drivers of critical event prediction, while higher age, anion gap, and C-reactive protein were the strongest drivers of mortality prediction. Conclusions: We externally and prospectively trained and validated machine learning models for mortality and critical events for patients with COVID-19 at different time horizons. These models identified at-risk patients and uncovered underlying relationships that predicted outcomes.},
language = {en}
}
@article{AbdallaAdamAharonianetal.2020,
author = {Abdalla, H. and Adam, R. and Aharonian, Felix A. and Benkhali, F. Ait and Ang{\"u}ner, Ekrem Oǧuzhan and Arcaro, C. and Armand, C. and Armstrong, T. and Ashkar, H. and Backes, M. and Baghmanyan, V. and Martins, V. Barbosa and Barnacka, A. and Barnard, M. and Becherini, Y. and Berge, D. and Bernlohr, K. and Bi, B. and Bottcher, M. and Boisson, C. and Bolmont, J. and de Lavergne, M. de Bony and Bordas, Pol and Breuhaus, M. and Brun, F. and Brun, P. and Bryan, M. and Buchele, M. and Bulik, T. and Bylund, T. and Caroff, S. and Carosi, A. and Casanova, Sabrina and Chand, T. and Chandra, S. and Chen, A. and Cotter, G. and Curylo, M. and Mbarubucyeye, J. Damascene and Davids, I. D. and Davies, J. and Deil, C. and Devin, J. and deWilt, P. and Dirson, L. and Djannati-Atai, A. and Dmytriiev, A. and Donath, A. and Doroshenko, V. and Duffy, C. and Dyks, J. and Egberts, Kathrin and Eichhorn, F. and Einecke, S. and Emery, G. and Ernenwein, J. -P. and Feijen, K. and Fegan, S. and Fiasson, A. and de Clairfontaine, G. Fichet and Fontaine, G. and Funk, S. and Fussling, Matthias and Gabici, S. and Gallant, Y. A. and Giavitto, G. and Giunti, L. and Glawion, D. and Glicenstein, J. F. and Gottschall, D. and Grondin, M. -H. and Hahn, J. and Haupt, M. and Hermann, G. and Hinton, J. A. and Hofmann, W. and Hoischen, Clemens and Holch, T. L. and Holler, M. and Horbe, M. and Horns, D. and Huber, D. and Jamrozy, M. and Jankowsky, D. and Jankowsky, F. and Jardin-Blicq, A. and Joshi, V. and Jung-Richardt, I. and Kasai, E. and Kastendieck, M. A. and Katarzynski, K. and Katz, U. and Khangulyan, D. and Khelifi, B. and Klepser, S. and Kluzniak, W. and Komin, Nu. and Konno, R. and Kosack, K. and Kostunin, D. and Kreter, M. and Lamanna, G. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Levy, C. and Lohse, T. and Lypova, I. and Mackey, J. and Majumdar, J. and Malyshev, D. and Malyshev, D. and Marandon, V. and Marchegiani, P. and Marcowith, Alexandre and Mares, A. and Marti-Devesa, G. and Marx, R. and Maurin, G. and Meintjes, P. J. and Meyer, M. and Mitchell, A. and Moderski, R. and Mohamed, M. and Mohrmann, L. and Montanari, A. and Moore, C. and Morris, P. and Moulin, Emmanuel and Muller, J. and Murach, T. and Nakashima, K. and Nayerhoda, A. and de Naurois, M. and Ndiyavala, H. and Niederwanger, F. and Niemiec, J. and Oakes, L. and O'Brien, Patrick and Odaka, H. and Ohm, S. and Olivera-Nieto, L. and Wilhelmi, E. de Ona and Ostrowski, M. and Oya, I. and Panter, M. and Panny, S. and Parsons, R. D. and Peron, G. and Peyaud, B. and Piel, Q. and Pita, S. and Poireau, V. and Noel, A. Priyana and Prokhorov, D. A. and Prokoph, H. and Puhlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Rauth, R. and Reichherzer, P. and Reimer, A. and Reimer, O. and Remy, Q. and Renaud, M. and Rieger, F. and Rinchiuso, L. and Romoli, C. and Rowell, G. and Rudak, B. and Ruiz-Velasco, E. and Sahakian, V. and Sailer, S. and Sanchez, D. A. and Santangelo, Andrea and Sasaki, M. and Scalici, M. and Schussler, F. and Schutte, H. M. and Schwanke, U. and Schwemmer, S. and Seglar-Arroyo, M. and Senniappan, M. and Seyffert, A. S. and Shafi, N. and Shiningayamwe, K. and Simoni, R. and Sinha, A. and Sol, H. and Specovius, A. and Spencer, S. and Spir-Jacob, M. and Stawarz, L. and Sun, L. and Steenkamp, R. and Stegmann, C. and Steinmassl, S. and Steppa, C. and Takahashi, T. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tiziani, D. and Tluczykont, M. and Tomankova, L. and Trichard, C. and Tsirou, M. and Tuffs, R. and Uchiyama, Y. and van der Walt, D. J. and van Eldik, C. and van Rensburg, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Vincent, P. and Vink, J. and Volk, H. J. and Vuillaume, T. and Wadiasingh, Z. and Wagner, S. J. and Watson, J. and Werner, F. and White, R. and Wierzcholska, A. and Wong, Yu Wun and Yusafzai, A. and Zacharias, M. and Zanin, R. and Zargaryan, D. and Zdziarski, A. A. and Zech, Alraune and Zhu, S. J. and Ziegler, A. and Zorn, J. and Zouari, S. and Zywucka, N.},
title = {An extreme particle accelerator in the Galactic plane},
series = {Astronomy and astrophysics : an international weekly journal},
volume = {644},
journal = {Astronomy and astrophysics : an international weekly journal},
publisher = {EDP Sciences},
address = {Les Ulis},
organization = {HESS Collaboration},
issn = {0004-6361},
doi = {10.1051/0004-6361/202038851},
pages = {8},
year = {2020},
abstract = {The unidentified very-high-energy (VHE; E > 0.1 TeV) gamma -ray source, HESS J1826-130, was discovered with the High Energy Stereoscopic System (HESS) in the Galactic plane. The analysis of 215 h of HESS data has revealed a steady gamma -ray flux from HESS J1826-130, which appears extended with a half-width of 0.21 degrees +/- 0.02
(stat)degrees
stat degrees +/- 0.05
(sys)degrees sys degrees . The source spectrum is best fit with either a power-law function with a spectral index Gamma = 1.78 +/- 0.10(stat) +/- 0.20(sys) and an exponential cut-off at 15.2
(+5.5)(-3.2) -3.2+5.5 TeV, or a broken power-law with Gamma (1) = 1.96 +/- 0.06(stat) +/- 0.20(sys), Gamma (2) = 3.59 +/- 0.69(stat) +/- 0.20(sys) for energies below and above E-br = 11.2 +/- 2.7 TeV, respectively. The VHE flux from HESS J1826-130 is contaminated by the extended emission of the bright, nearby pulsar wind nebula, HESS J1825-137, particularly at the low end of the energy spectrum. Leptonic scenarios for the origin of HESS J1826-130 VHE emission related to PSR J1826-1256 are confronted by our spectral and morphological analysis. In a hadronic framework, taking into account the properties of dense gas regions surrounding HESS J1826-130, the source spectrum would imply an astrophysical object capable of accelerating the parent particle population up to greater than or similar to 200 TeV. Our results are also discussed in a multiwavelength context, accounting for both the presence of nearby supernova remnants, molecular clouds, and counterparts detected in radio, X-rays, and TeV energies.},
language = {en}
}
@article{GorskiJungLietal.2020,
author = {Gorski, Mathias and Jung, Bettina and Li, Yong and Matias-Garcia, Pamela R. and Wuttke, Matthias and Coassin, Stefan and Thio, Chris H. L. and Kleber, Marcus E. and Winkler, Thomas W. and Wanner, Veronika and Chai, Jin-Fang and Chu, Audrey Y. and Cocca, Massimiliano and Feitosa, Mary F. and Ghasemi, Sahar and Hoppmann, Anselm and Horn, Katrin and Li, Man and Nutile, Teresa and Scholz, Markus and Sieber, Karsten B. and Teumer, Alexander and Tin, Adrienne and Wang, Judy and Tayo, Bamidele O. and Ahluwalia, Tarunveer S. and Almgren, Peter and Bakker, Stephan J. L. and Banas, Bernhard and Bansal, Nisha and Biggs, Mary L. and Boerwinkle, Eric and B{\"o}ttinger, Erwin and Brenner, Hermann and Carroll, Robert J. and Chalmers, John and Chee, Miao-Li and Chee, Miao-Ling and Cheng, Ching-Yu and Coresh, Josef and de Borst, Martin H. and Degenhardt, Frauke and Eckardt, Kai-Uwe and Endlich, Karlhans and Franke, Andre and Freitag-Wolf, Sandra and Gampawar, Piyush and Gansevoort, Ron T. and Ghanbari, Mohsen and Gieger, Christian and Hamet, Pavel and Ho, Kevin and Hofer, Edith and Holleczek, Bernd and Foo, Valencia Hui Xian and Hutri-Kahonen, Nina and Hwang, Shih-Jen and Ikram, M. Arfan and Josyula, Navya Shilpa and Kahonen, Mika and Khor, Chiea-Chuen and Koenig, Wolfgang and Kramer, Holly and Kraemer, Bernhard K. and Kuehnel, Brigitte and Lange, Leslie A. and Lehtimaki, Terho and Lieb, Wolfgang and Loos, Ruth J. F. and Lukas, Mary Ann and Lyytikainen, Leo-Pekka and Meisinger, Christa and Meitinger, Thomas and Melander, Olle and Milaneschi, Yuri and Mishra, Pashupati P. and Mononen, Nina and Mychaleckyj, Josyf C. and Nadkarni, Girish N. and Nauck, Matthias and Nikus, Kjell and Ning, Boting and Nolte, Ilja M. and O'Donoghue, Michelle L. and Orho-Melander, Marju and Pendergrass, Sarah A. and Penninx, Brenda W. J. H. and Preuss, Michael H. and Psaty, Bruce M. and Raffield, Laura M. and Raitakari, Olli T. and Rettig, Rainer and Rheinberger, Myriam and Rice, Kenneth M. and Rosenkranz, Alexander R. and Rossing, Peter and Rotter, Jerome and Sabanayagam, Charumathi and Schmidt, Helena and Schmidt, Reinhold and Schoettker, Ben and Schulz, Christina-Alexandra and Sedaghat, Sanaz and Shaffer, Christian M. and Strauch, Konstantin and Szymczak, Silke and Taylor, Kent D. and Tremblay, Johanne and Chaker, Layal and van der Harst, Pim and van der Most, Peter J. and Verweij, Niek and Voelker, Uwe and Waldenberger, Melanie and Wallentin, Lars and Waterworth, Dawn M. and White, Harvey D. and Wilson, James G. and Wong, Tien-Yin and Woodward, Mark and Yang, Qiong and Yasuda, Masayuki and Yerges-Armstrong, Laura M. and Zhang, Yan and Snieder, Harold and Wanner, Christoph and Boger, Carsten A. and Kottgen, Anna and Kronenberg, Florian and Pattaro, Cristian and Heid, Iris M.},
title = {Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline},
series = {Kidney international : official journal of the International Society of Nephrology},
volume = {99},
journal = {Kidney international : official journal of the International Society of Nephrology},
number = {4},
publisher = {Elsevier},
address = {New York},
organization = {Lifelines Cohort Study
Regeneron Genetics Ctr},
issn = {0085-2538},
doi = {10.1016/j.kint.2020.09.030},
pages = {926 -- 939},
year = {2020},
abstract = {Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25\% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95\% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function.},
language = {en}
}
@article{DengWangXuaetal.2020,
author = {Deng, Zijun and Wang, Weiwei and Xua, Xun and Gould, Oliver E. C. and Kratz, Karl and Ma, Nan and Lendlein, Andreas},
title = {Polymeric sheet actuators with programmable bioinstructivity},
series = {PNAS},
volume = {117},
journal = {PNAS},
number = {4},
publisher = {National Academy of Sciences},
address = {Washington, DC},
issn = {1091-6490},
doi = {10.1073/pnas.1910668117},
pages = {1895 -- 1901},
year = {2020},
abstract = {Stem cells are capable of sensing and processing environmental inputs, converting this information to output a specific cell lineage through signaling cascades. Despite the combinatorial nature of mechanical, thermal, and biochemical signals, these stimuli have typically been decoupled and applied independently, requiring continuous regulation by controlling units. We employ a programmable polymer actuator sheet to autonomously synchronize thermal and mechanical signals applied to mesenchymal stem cells (MSC5). Using a grid on its underside, the shape change of polymer sheet, as well as cell morphology, calcium (Ca2+) influx, and focal adhesion assembly, could be visualized and quantified. This paper gives compelling evidence that the temperature sensing and mechanosensing of MSC5 are interconnected via intracellular Ca2+. Up-regulated Ca2+ levels lead to a remarkable alteration of histone H3K9 acetylation and activation of osteogenic related genes. The interplay of physical, thermal, and biochemical signaling was utilized to accelerate the cell differentiation toward osteogenic lineage. The approach of programmable bioinstructivity provides a fundamental principle for functional biomaterials exhibiting multifaceted stimuli on differentiation programs. Technological impact is expected in the tissue engineering of periosteum for treating bone defects.},
language = {en}
}
@misc{NoonanFlemingTuckeretal.2020,
author = {Noonan, Michael J. and Fleming, Christen H. and Tucker, Marlee A. and Kays, Roland and Harrison, Autumn-Lynn and Crofoot, Margaret C. and Abrahms, Briana and Alberts, Susan C. and Ali, Abdullahi H. and Blaum, Niels},
title = {Effects of body size on estimation of mammalian area requirements},
series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
number = {4},
issn = {1866-8372},
doi = {10.25932/publishup-52682},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-526824},
pages = {14},
year = {2020},
abstract = {Accurately quantifying species' area requirements is a prerequisite for effective area-based conservation. This typically involves collecting tracking data on species of interest and then conducting home-range analyses. Problematically, autocorrelation in tracking data can result in space needs being severely underestimated. Based on the previous work, we hypothesized the magnitude of underestimation varies with body mass, a relationship that could have serious conservation implications. To evaluate this hypothesis for terrestrial mammals, we estimated home-range areas with global positioning system (GPS) locations from 757 individuals across 61 globally distributed mammalian species with body masses ranging from 0.4 to 4000 kg. We then applied block cross-validation to quantify bias in empirical home-range estimates. Area requirements of mammals <10 kg were underestimated by a mean approximately15\%, and species weighing approximately100 kg were underestimated by approximately50\% on average. Thus, we found area estimation was subject to autocorrelation-induced bias that was worse for large species. Combined with the fact that extinction risk increases as body mass increases, the allometric scaling of bias we observed suggests the most threatened species are also likely to be those with the least accurate home-range estimates. As a correction, we tested whether data thinning or autocorrelation-informed home-range estimation minimized the scaling effect of autocorrelation on area estimates. Data thinning required an approximately93\% data loss to achieve statistical independence with 95\% confidence and was, therefore, not a viable solution. In contrast, autocorrelation-informed home-range estimation resulted in consistently accurate estimates irrespective of mass. When relating body mass to home range size, we detected that correcting for autocorrelation resulted in a scaling exponent significantly >1, meaning the scaling of the relationship changed substantially at the upper end of the mass spectrum.},
language = {en}
}
@article{GriscomBuschCookPattonetal.2020,
author = {Griscom, Bronson W. and Busch, Jonah and Cook-Patton, Susan C. and Ellis, Peter W. and Funk, Jason and Leavitt, Sara M. and Lomax, Guy and Turner, Will R. and Chapman, Melissa and Streck, Charlotte},
title = {National mitigation potential from natural climate solutions in the tropics},
series = {Biological sciences},
volume = {375},
journal = {Biological sciences},
number = {1794},
publisher = {The Royal Society Publishing},
address = {London},
issn = {0962-8436},
doi = {10.1098/rstb.2019.0126},
pages = {1 -- 11},
year = {2020},
abstract = {Better land stewardship is needed to achieve the Paris Agreement's temperature goal, particularly in the tropics, where greenhouse gas emissions from the destruction of ecosystems are largest, and where the potential for additional land carbon storage is greatest. As countries enhance their nationally determined contributions (NDCs) to the Paris Agreement, confusion persists about the potential contribution of better land stewardship to meeting the Agreement's goal to hold global warming below 2 degrees C. We assess cost-effective tropical country-level potential of natural climate solutions (NCS)-protection, improved management and restoration of ecosystems-to deliver climate mitigation linked with sustainable development goals (SDGs). We identify groups of countries with distinctive NCS portfolios, and we explore factors (governance, financial capacity) influencing the feasibility of unlocking national NCS potential. Cost-effective tropical NCS offers globally significant climate mitigation in the coming decades (6.56 Pg CO(2)e yr(-1) at less than 100 US\$ per Mg CO(2)e). In half of the tropical countries, cost-effective NCS could mitigate over half of national emissions. In more than a quarter of tropical countries, cost-effective NCS potential is greater than national emissions. We identify countries where, with international financing and political will, NCS can cost-effectively deliver the majority of enhanced NDCs while transforming national economies and contributing to SDGs. This article is part of the theme issue 'Climate change and ecosystems: threats, opportunities and solutions'.},
language = {en}
}
@misc{DietzeMangelsdorfAndreevetal.2020,
author = {Dietze, Elisabeth and Mangelsdorf, Kai and Andreev, Andrei and Karger, Cornelia and Schreuder, Laura T. and Hopmans, Ellen C. and Rach, Oliver and Sachse, Dirk and Wennrich, Volker and Herzschuh, Ulrike},
title = {Relationships between low-temperature fires, climate and vegetation during three late glacials and interglacials of the last 430 kyr in northeastern Siberia reconstructed from monosaccharide anhydrides in Lake El'gygytgyn sediments},
series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
journal = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
number = {2},
issn = {1866-8372},
doi = {10.25932/publishup-51684},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-516843},
pages = {22},
year = {2020},
abstract = {Landscapes in high northern latitudes are assumed to be highly sensitive to future global change, but the rates and long-term trajectories of changes are rather uncertain. In the boreal zone, fires are an important factor in climate-vegetation interactions and biogeochemical cycles. Fire regimes are characterized by small, frequent, low-intensity fires within summergreen boreal forests dominated by larch, whereas evergreen boreal forests dominated by spruce and pine burn large areas less frequently but at higher intensities. Here, we explore the potential of the monosaccharide anhydrides (MA) levoglucosan, mannosan and galactosan to serve as proxies of low-intensity biomass burning in glacial-to-interglacial lake sediments from the high northern latitudes. We use sediments from Lake El'gygytgyn (cores PG 1351 and ICDP 5011-1), located in the far north-east of Russia, and study glacial and interglacial samples of the last 430 kyr (marine isotope stages 5e, 6, 7e, 8, 11c and 12) that had different climate and biome configurations. Combined with pollen and non-pollen palynomorph records from the same samples, we assess how far the modern relationships between fire, climate and vegetation persisted during the past, on orbital to centennial timescales. We find that MAs attached to particulates were well-preserved in up to 430 kyr old sediments with higher influxes from low-intensity biomass burning in interglacials compared to glacials. MA influxes significantly increase when summergreen boreal forest spreads closer to the lake, whereas they decrease when tundra-steppe environments and, especially, Sphagnum peatlands spread. This suggests that low-temperature fires are a typical characteristic of Siberian larch forests also on long timescales. The results also suggest that low-intensity fires would be reduced by vegetation shifts towards very dry environments due to reduced biomass availability, as well as by shifts towards peatlands, which limits fuel dryness. In addition, we observed very low MA ratios, which we interpret as high contributions of galactosan and mannosan from biomass sources other than those currently monitored, such as the moss-lichen mats in the understorey of the summergreen boreal forest. Overall, sedimentary MAs can provide a powerful proxy for fire regime reconstructions and extend our knowledge of long-term natural fire-climate-vegetation feedbacks in the high northern latitudes.},
language = {en}
}
@article{PiroDadiSeileretal.2020,
author = {Piro, Vitor C. and Dadi, Temesgen H. and Seiler, Enrico and Reinert, Knut and Renard, Bernhard Y.},
title = {ganon},
series = {Bioinformatics},
volume = {36},
journal = {Bioinformatics},
publisher = {Oxford Univ. Press},
address = {Oxford},
issn = {1367-4811},
doi = {https://doi.org/10.1093/bioinformatics/btaa458},
pages = {12 -- 20},
year = {2020},
abstract = {Motivation: The exponential growth of assembled genome sequences greatly benefits metagenomics studies. However, currently available methods struggle to manage the increasing amount of sequences and their frequent updates. Indexing the current RefSeq can take days and hundreds of GB of memory on large servers. Few methods address these issues thus far, and even though many can theoretically handle large amounts of references, time/memory requirements are prohibitive in practice. As a result, many studies that require sequence classification use often outdated and almost never truly up-to-date indices. Results: Motivated by those limitations, we created ganon, a k-mer-based read classification tool that uses Interleaved Bloom Filters in conjunction with a taxonomic clustering and a k-mer counting/filtering scheme. Ganon provides an efficient method for indexing references, keeping them updated. It requires <55 min to index the complete RefSeq of bacteria, archaea, fungi and viruses. The tool can further keep these indices up-to-date in a fraction of the time necessary to create them. Ganon makes it possible to query against very large reference sets and therefore it classifies significantly more reads and identifies more species than similar methods. When classifying a high-complexity CAMI challenge dataset against complete genomes from RefSeq, ganon shows strongly increased precision with equal or better sensitivity compared with state-of-the-art tools. With the same dataset against the complete RefSeq, ganon improved the F1-score by 65\% at the genus level. It supports taxonomy- and assembly-level classification, multiple indices and hierarchical classification.},
language = {en}
}
@article{DietzeMangelsdorfAndreevetal.2020,
author = {Dietze, Elisabeth and Mangelsdorf, Kai and Andreev, Andrei and Karger, Cornelia and Schreuder, Laura T. and Hopmans, Ellen C. and Rach, Oliver and Sachse, Dirk and Wennrich, Volker and Herzschuh, Ulrike},
title = {Relationships between low-temperature fires, climate and vegetation during three late glacials and interglacials of the last 430 kyr in northeastern Siberia reconstructed from monosaccharide anhydrides in Lake El'gygytgyn sediments},
series = {Climate of the Past},
volume = {16},
journal = {Climate of the Past},
number = {2},
publisher = {Copernicus Publications},
address = {G{\"o}ttingen},
issn = {1814-9332},
doi = {10.5194/cp-16-799-2020},
pages = {788 -- 818},
year = {2020},
abstract = {Landscapes in high northern latitudes are assumed to be highly sensitive to future global change, but the rates and long-term trajectories of changes are rather uncertain. In the boreal zone, fires are an important factor in climate-vegetation interactions and biogeochemical cycles. Fire regimes are characterized by small, frequent, low-intensity fires within summergreen boreal forests dominated by larch, whereas evergreen boreal forests dominated by spruce and pine burn large areas less frequently but at higher intensities. Here, we explore the potential of the monosaccharide anhydrides (MA) levoglucosan, mannosan and galactosan to serve as proxies of low-intensity biomass burning in glacial-to-interglacial lake sediments from the high northern latitudes. We use sediments from Lake El'gygytgyn (cores PG 1351 and ICDP 5011-1), located in the far north-east of Russia, and study glacial and interglacial samples of the last 430 kyr (marine isotope stages 5e, 6, 7e, 8, 11c and 12) that had different climate and biome configurations. Combined with pollen and non-pollen palynomorph records from the same samples, we assess how far the modern relationships between fire, climate and vegetation persisted during the past, on orbital to centennial timescales. We find that MAs attached to particulates were well-preserved in up to 430 kyr old sediments with higher influxes from low-intensity biomass burning in interglacials compared to glacials. MA influxes significantly increase when summergreen boreal forest spreads closer to the lake, whereas they decrease when tundra-steppe environments and, especially, Sphagnum peatlands spread. This suggests that low-temperature fires are a typical characteristic of Siberian larch forests also on long timescales. The results also suggest that low-intensity fires would be reduced by vegetation shifts towards very dry environments due to reduced biomass availability, as well as by shifts towards peatlands, which limits fuel dryness. In addition, we observed very low MA ratios, which we interpret as high contributions of galactosan and mannosan from biomass sources other than those currently monitored, such as the moss-lichen mats in the understorey of the summergreen boreal forest. Overall, sedimentary MAs can provide a powerful proxy for fire regime reconstructions and extend our knowledge of long-term natural fire-climate-vegetation feedbacks in the high northern latitudes.},
language = {en}
}
@article{PostClassKohler2020,
author = {Post, Julia C. and Class, Fabian and Kohler, Ulrich},
title = {Unit nonresponse biases in estimates of SARS-CoV-2 prevalence},
series = {Survey research methods},
volume = {14},
journal = {Survey research methods},
number = {2},
publisher = {European Survey Research Association},
address = {Duisburg},
issn = {1864-3361},
doi = {10.18148/srm/2020.v14i2.7755},
pages = {115 -- 121},
year = {2020},
abstract = {Since COVID-19 became a pandemic, many studies are being conducted to get a better understanding of the disease itself and its spread. One crucial indicator is the prevalence of SARS-CoV-2 infections. Since this measure is an important foundation for political decisions, its estimate must be reliable and unbiased. This paper presents reasons for biases in prevalence estimates due to unit nonresponse in typical studies. Since it is difficult to avoid bias in situations with mostly unknown nonresponse mechanisms, we propose the maximum amount of bias as one measure to assess the uncertainty due to nonresponse. An interactive web application is presented that calculates the limits of such a conservative unit nonresponse confidence interval (CUNCI).},
language = {en}
}
@article{NoonanFlemingTuckeretal.2020,
author = {Noonan, Michael J. and Fleming, Christen H. and Tucker, Marlee A. and Kays, Roland and Harrison, Autumn-Lynn and Crofoot, Margaret C. and Abrahms, Briana and Alberts, Susan C. and Ali, Abdullahi H. and Blaum, Niels},
title = {Effects of body size on estimation of mammalian area requirements},
series = {Conservation Biology},
volume = {34},
journal = {Conservation Biology},
number = {4},
publisher = {Wiley-Blackwell},
address = {Oxford},
pages = {12},
year = {2020},
abstract = {Accurately quantifying species' area requirements is a prerequisite for effective area-based conservation. This typically involves collecting tracking data on species of interest and then conducting home-range analyses. Problematically, autocorrelation in tracking data can result in space needs being severely underestimated. Based on the previous work, we hypothesized the magnitude of underestimation varies with body mass, a relationship that could have serious conservation implications. To evaluate this hypothesis for terrestrial mammals, we estimated home-range areas with global positioning system (GPS) locations from 757 individuals across 61 globally distributed mammalian species with body masses ranging from 0.4 to 4000 kg. We then applied block cross-validation to quantify bias in empirical home-range estimates. Area requirements of mammals <10 kg were underestimated by a mean approximately15\%, and species weighing approximately100 kg were underestimated by approximately50\% on average. Thus, we found area estimation was subject to autocorrelation-induced bias that was worse for large species. Combined with the fact that extinction risk increases as body mass increases, the allometric scaling of bias we observed suggests the most threatened species are also likely to be those with the least accurate home-range estimates. As a correction, we tested whether data thinning or autocorrelation-informed home-range estimation minimized the scaling effect of autocorrelation on area estimates. Data thinning required an approximately93\% data loss to achieve statistical independence with 95\% confidence and was, therefore, not a viable solution. In contrast, autocorrelation-informed home-range estimation resulted in consistently accurate estimates irrespective of mass. When relating body mass to home range size, we detected that correcting for autocorrelation resulted in a scaling exponent significantly >1, meaning the scaling of the relationship changed substantially at the upper end of the mass spectrum.},
language = {en}
}
@misc{vanReesWaylenSchmidtKloiberetal.2020,
author = {van Rees, Charles B. and Waylen, Kerry A. and Schmidt-Kloiber, Astrid and Thackeray, Stephen J. and Kalinkat, Gregor and Martens, Koen and Domisch, Sami and Lillebo, Ana and Hermoso, Virgilio and Grossart, Hans-Peter and Schinegger, Rafaela and Decleer, Kris and Adriaens, Tim and Denys, Luc and Jaric, Ivan and Janse, Jan H. and Monaghan, Michael T. and De Wever, Aaike and Geijzendorffer, Ilse and Adamescu, Mihai C. and J{\"a}hnig, Sonja C.},
title = {Safeguarding freshwater life beyond 2020},
series = {Conservation letters},
volume = {14},
journal = {Conservation letters},
number = {1},
publisher = {Wiley},
address = {Hoboken},
issn = {1755-263X},
doi = {10.1111/conl.12771},
pages = {17},
year = {2020},
abstract = {Plans are currently being drafted for the next decade of action on biodiversity-both the post-2020 Global Biodiversity Framework of the Convention on Biological Diversity (CBD) and Biodiversity Strategy of the European Union (EU). Freshwater biodiversity is disproportionately threatened and underprioritized relative to the marine and terrestrial biota, despite supporting a richness of species and ecosystems with their own intrinsic value and providing multiple essential ecosystem services. Future policies and strategies must have a greater focus on the unique ecology of freshwater life and its multiple threats, and now is a critical time to reflect on how this may be achieved. We identify priority topics including environmental flows, water quality, invasive species, integrated water resources management, strategic conservation planning, and emerging technologies for freshwater ecosystem monitoring. We synthesize these topics with decades of first-hand experience and recent literature into 14 special recommendations for global freshwater biodiversity conservation based on the successes and setbacks of European policy, management, and research. Applying and following these recommendations will inform and enhance the ability of global and European post-2020 biodiversity agreements to halt and reverse the rapid global decline of freshwater biodiversity.},
language = {en}
}
@book{ZhangPlauthEberhardtetal.2020,
author = {Zhang, Shuhao and Plauth, Max and Eberhardt, Felix and Polze, Andreas and Lehmann, Jens and Sejdiu, Gezim and Jabeen, Hajira and Servadei, Lorenzo and M{\"o}stl, Christian and B{\"a}r, Florian and Netzeband, Andr{\´e} and Schmidt, Rainer and Knigge, Marlene and Hecht, Sonja and Prifti, Loina and Krcmar, Helmut and Sapegin, Andrey and Jaeger, David and Cheng, Feng and Meinel, Christoph and Friedrich, Tobias and Rothenberger, Ralf and Sutton, Andrew M. and Sidorova, Julia A. and Lundberg, Lars and Rosander, Oliver and Sk{\"o}ld, Lars and Di Varano, Igor and van der Walt, Est{\´e}e and Eloff, Jan H. P. and Fabian, Benjamin and Baumann, Annika and Ermakova, Tatiana and Kelkel, Stefan and Choudhary, Yash and Cooray, Thilini and Rodr{\´i}guez, Jorge and Medina-P{\´e}rez, Miguel Angel and Trejo, Luis A. and Barrera-Animas, Ari Yair and Monroy-Borja, Ra{\´u}l and L{\´o}pez-Cuevas, Armando and Ram{\´i}rez-M{\´a}rquez, Jos{\´e} Emmanuel and Grohmann, Maria and Niederleithinger, Ernst and Podapati, Sasidhar and Schmidt, Christopher and Huegle, Johannes and de Oliveira, Roberto C. L. and Soares, F{\´a}bio Mendes and van Hoorn, Andr{\´e} and Neumer, Tamas and Willnecker, Felix and Wilhelm, Mathias and Kuster, Bernhard},
title = {HPI Future SOC Lab - Proceedings 2017},
number = {130},
editor = {Meinel, Christoph and Polze, Andreas and Beins, Karsten and Strotmann, Rolf and Seibold, Ulrich and R{\"o}dszus, Kurt and M{\"u}ller, J{\"u}rgen},
publisher = {Universit{\"a}tsverlag Potsdam},
address = {Potsdam},
isbn = {978-3-86956-475-3},
issn = {1613-5652},
doi = {10.25932/publishup-43310},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-433100},
publisher = {Universit{\"a}t Potsdam},
pages = {ix, 235},
year = {2020},
abstract = {The "HPI Future SOC Lab" is a cooperation of the Hasso Plattner Institute (HPI) and industry partners. Its mission is to enable and promote exchange and interaction between the research community and the industry partners. The HPI Future SOC Lab provides researchers with free of charge access to a complete infrastructure of state of the art hard and software. This infrastructure includes components, which might be too expensive for an ordinary research environment, such as servers with up to 64 cores and 2 TB main memory. The offerings address researchers particularly from but not limited to the areas of computer science and business information systems. Main areas of research include cloud computing, parallelization, and In-Memory technologies. This technical report presents results of research projects executed in 2017. Selected projects have presented their results on April 25th and November 15th 2017 at the Future SOC Lab Day events.},
language = {en}
}
@article{AraziAsadiKhalkhalietal.2020,
author = {Arazi, Hamid and Asadi, Abbas and Khalkhali, Farhood and Boullosa, Daniel and Hackney, Anthony C. and Granacher, Urs and Zouhal, Hassane},
title = {Association Between the Acute to Chronic Workload Ratio and Injury Occurrence in Young Male Team Soccer Players},
series = {Frontiers in Physiology},
volume = {11},
journal = {Frontiers in Physiology},
publisher = {Frontiers Research Foundation},
address = {Lausanne},
issn = {1664-042X},
doi = {10.3389/fphys.2020.00608},
pages = {7},
year = {2020},
abstract = {This study aimed to investigate the relationship between the acute to chronic workload ratio (ACWR), based upon participant session rating of perceived exertion (sRPE), using two models [(1) rolling averages (ACWRRA); and (2) exponentially weighted moving averages (ACWREWMA)] and the injury rate in young male team soccer players aged 17.1 ± 0.7 years during a competitive mesocycle. Twenty-two players were enrolled in this study and performed four training sessions per week with 2 days of recovery and 1 match day per week. During each training session and each weekly match, training time and sRPE were recorded. In addition, training impulse (TRIMP), monotony, and strain were subsequently calculated. The rate of injury was recorded for each soccer player over a period of 4 weeks (i.e., 28 days) using a daily questionnaire. The results showed that over the course of the study, the number of non-contact injuries was significantly higher than that for contact injuries (2.5 vs. 0.5, p = 0.01). There were also significant positive correlations between sRPE and training time (r = 0.411, p = 0.039), ACWRRA (r = 0.47, p = 0.049), and ACWREWMA (r = 0.51, p = 0.038). In addition, small-to-medium correlations were detected between ACWR and non-contact injury occurrence (ACWRRA, r = 0.31, p = 0.05; ACWREWMA, r = 0.53, p = 0.03). Explained variance (r 2) for non-contact injury was significantly greater using the ACWREWMA model (ranging between 21 and 52\%) compared with ACWRRA (ranging between 17 and 39\%). In conclusion, the results of this study showed that the ACWREWMA model is more sensitive than ACWRRA to identify non-contact injury occurrence in male team soccer players during a short period in the competitive season.},
language = {en}
}
@article{KoenigAblerAgartzetal.2020,
author = {Koenig, Julian and Abler, Birgit and Agartz, Ingrid and akerstedt, Torbjorn and Andreassen, Ole A. and Anthony, Mia and Baer, Karl-Juergen and Bertsch, Katja and Brown, Rebecca C. and Brunner, Romuald and Carnevali, Luca and Critchley, Hugo D. and Cullen, Kathryn R. and de Geus, Eco J. C. and de la Cruz, Feliberto and Dziobek, Isabel and Ferger, Marc D. and Fischer, Hakan and Flor, Herta and Gaebler, Michael and Gianaros, Peter J. and Giummarra, Melita J. and Greening, Steven G. and Guendelman, Simon and Heathers, James A. J. and Herpertz, Sabine C. and Hu, Mandy X. and Jentschke, Sebastian and Kaess, Michael and Kaufmann, Tobias and Klimes-Dougan, Bonnie and Koelsch, Stefan and Krauch, Marlene and Kumral, Deniz and Lamers, Femke and Lee, Tae-Ho and Lekander, Mats and Lin, Feng and Lotze, Martin and Makovac, Elena and Mancini, Matteo and Mancke, Falk and Mansson, Kristoffer N. T. and Manuck, Stephen B. and Mather, Mara and Meeten, Frances and Min, Jungwon and Mueller, Bryon and Muench, Vera and Nees, Frauke and Nga, Lin and Nilsonne, Gustav and Ordonez Acuna, Daniela and Osnes, Berge and Ottaviani, Cristina and Penninx, Brenda W. J. H. and Ponzio, Allison and Poudel, Govinda R. and Reinelt, Janis and Ren, Ping and Sakaki, Michiko and Schumann, Andy and Sorensen, Lin and Specht, Karsten and Straub, Joana and Tamm, Sandra and Thai, Michelle and Thayer, Julian F. and Ubani, Benjamin and van Der Mee, Denise J. and van Velzen, Laura S. and Ventura-Bort, Carlos and Villringer, Arno and Watson, David R. and Wei, Luqing and Wendt, Julia and Schreiner, Melinda Westlund and Westlye, Lars T. and Weymar, Mathias and Winkelmann, Tobias and Wu, Guo-Rong and Yoo, Hyun Joo and Quintana, Daniel S.},
title = {Cortical thickness and resting-state cardiac function across the lifespan},
series = {Psychophysiology : journal of the Society for Psychophysiological Research},
volume = {58},
journal = {Psychophysiology : journal of the Society for Psychophysiological Research},
number = {7},
publisher = {Wiley},
address = {Hoboken},
issn = {0048-5772},
doi = {10.1111/psyp.13688},
pages = {16},
year = {2020},
abstract = {Understanding the association between autonomic nervous system [ANS] function and brain morphology across the lifespan provides important insights into neurovisceral mechanisms underlying health and disease. Resting-state ANS activity, indexed by measures of heart rate [HR] and its variability [HRV] has been associated with brain morphology, particularly cortical thickness [CT]. While findings have been mixed regarding the anatomical distribution and direction of the associations, these inconsistencies may be due to sex and age differences in HR/HRV and CT. Previous studies have been limited by small sample sizes, which impede the assessment of sex differences and aging effects on the association between ANS function and CT. To overcome these limitations, 20 groups worldwide contributed data collected under similar protocols of CT assessment and HR/HRV recording to be pooled in a mega-analysis (N = 1,218 (50.5\% female), mean age 36.7 years (range: 12-87)). Findings suggest a decline in HRV as well as CT with increasing age. CT, particularly in the orbitofrontal cortex, explained additional variance in HRV, beyond the effects of aging. This pattern of results may suggest that the decline in HRV with increasing age is related to a decline in orbitofrontal CT. These effects were independent of sex and specific to HRV; with no significant association between CT and HR. Greater CT across the adult lifespan may be vital for the maintenance of healthy cardiac regulation via the ANS-or greater cardiac vagal activity as indirectly reflected in HRV may slow brain atrophy. Findings reveal an important association between CT and cardiac parasympathetic activity with implications for healthy aging and longevity that should be studied further in longitudinal research.},
language = {en}
}
@article{SchenckHarischDietrichetal.2021,
author = {Schenck, Marcia C. and Harisch, Immanuel R. and Dietrich, Anne and Burton, Eric},
title = {Introduction},
series = {Navigating Socialist Encounters},
journal = {Navigating Socialist Encounters},
publisher = {de Gruyter},
address = {Oldenburg},
isbn = {978-3-11-062354-3},
doi = {10.1515/9783110623543-001},
pages = {1 -- 58},
year = {2021},
language = {en}
}
@article{SchenckRaposo2021,
author = {Schenck, Marcia C. and Raposo, Francisca},
title = {Socialist Encounters at the School of Friendship},
series = {Navigating Socialist Encounters},
journal = {Navigating Socialist Encounters},
publisher = {de Gruyter},
address = {Oldenburg},
isbn = {978-3-11-062354-3},
doi = {10.1515/9783110623543-009},
pages = {235 -- 246},
year = {2021},
language = {en}
}
@article{AlbertoSchenck2021,
author = {Alberto, Ibraimo and Schenck, Marcia C.},
title = {Paths Are Made by Walking},
series = {Navigating Socialist Encounters},
journal = {Navigating Socialist Encounters},
publisher = {de Gruyter},
address = {Oldenburg},
isbn = {978-3-11-062354-3},
doi = {10.1515/9783110623543-010},
pages = {247 -- 262},
year = {2021},
language = {en}
}
@article{BienertHuebner2021,
author = {Bienert, Michael C. and H{\"u}bner, Kristina},
title = {Der Freistaat Preußen in der Weimarer Republik},
series = {Preußen : Geschichte eines Mythos},
journal = {Preußen : Geschichte eines Mythos},
publisher = {be.bra},
address = {Berlin},
isbn = {978-3-89809-095-7},
pages = {170 -- 197},
year = {2021},
language = {de}
}
@misc{Schenck2021,
author = {Schenck, Marcia C.},
title = {Rezension zu: Guthrie, Zachary Kagan: Bound for Work: Labor, Mobility, and Colonial Rule in Central Mozambique, 1940-1965. - Charlottesville: University of Virginia Press, 2018. vii + 240 pp. - ISBN 978-0-8139-4154-7},
series = {Labor: studies in working-class history of the Americas},
volume = {18},
journal = {Labor: studies in working-class history of the Americas},
number = {2},
publisher = {Duke University Press},
address = {Durham, NC},
isbn = {978-0-8139-4154-7},
issn = {1558-1454},
doi = {10.1215/15476715-8849376},
pages = {120 -- 121},
year = {2021},
language = {en}
}
@incollection{SchenckMohamedZakariaNdiritiroetal.2021,
author = {Schenck, Marcia C. and Mohamed Zakaria, Abdalla and Ndiritiro, Richesse and Omar, Shaema and Rer, Samson and Reed, Kate and Teferra, Gerawork},
title = {Opportunities and challenges of oral history research through refugee voices, narratives, and memories},
series = {Global South scholars in the Western Academy},
booktitle = {Global South scholars in the Western Academy},
publisher = {Routledge},
address = {New York},
isbn = {978-0-367-62582-5},
doi = {10.4324/9781003109808-18},
pages = {171 -- 185},
year = {2021},
abstract = {While academic mobility has generally been positioned in the literature as a ready, at-will movement of people and ideas, this chapter demonstrates how the conditions of mobility and immobility "all at once" impact knowledge production and exchange. By offering a more nuanced window into the experiences of scholars in exile, this chapter challenges dominant discourses of academic mobility and draws on lessons learned from within liminal spaces of knowledge production to elicit more response within higher education communities. Context-rich examples reveal the interpersonal tensions and cultural shifts—including gender, ethnic and race-based stereotypes and discrimination—that affect intellectual outputs, further problematizing the conceptualization of knowledge production in human capital terms. Lessons gleaned from Scholars at Risk (SAR) and related programmes suggest support structures that amplify scholars' agency; more broadly, higher education should consider ways of adapting to its diverse knowledge producers, rather than supporting the acclimation to its current environment.},
language = {en}
}
@article{StrongScherzCaldwell2021,
author = {Strong, Catherine R. C. and Scherz, Mark D. and Caldwell, Michael Wayne},
title = {Deconstructing the Gestalt},
series = {The anatomical record : AR ; advances in integrative anatomy and evolutionary biology ; an official publication of the American Association of Anatomists, AAA},
volume = {304},
journal = {The anatomical record : AR ; advances in integrative anatomy and evolutionary biology ; an official publication of the American Association of Anatomists, AAA},
number = {10},
publisher = {Wiley},
address = {Hoboken},
issn = {1932-8486},
doi = {10.1002/ar.24630},
pages = {2303 -- 2351},
year = {2021},
abstract = {Snakes-a subset of lizards-have traditionally been divided into two major groups based on feeding mechanics: "macrostomy," involving the ingestion of proportionally large prey items; and "microstomy," the lack of this ability. "Microstomy"-considered present in scolecophidian and early-diverging alethinophidian snakes-is generally viewed as a symplesiomorphy shared with non-snake lizards. However, this perspective of "microstomy" as plesiomorphic and morphologically homogenous fails to recognize the complexity of this condition and its evolution across "microstomatan" squamates. To challenge this problematic paradigm, we formalize a new framework for conceptualizing and testing the homology of overall character complexes, or "morphotypes," which underlies our re-assessment of "microstomy." Using micro-computed tomography (micro-CT) scans, we analyze the morphology of the jaws and suspensorium across purported "microstomatan" squamates (scolecophidians, early-diverging alethinophidians, and non-snake lizards) and demonstrate that key components of the jaw complex are not homologous at the level of primary character state identity across these taxa. Therefore, rather than treating "microstomy" as a uniform condition, we instead propose that non-snake lizards, early-diverging alethinophidians, anomalepidids, leptotyphlopids, and typhlopoids each exhibit a unique and nonhomologous jaw morphotype: "minimal-kinesis microstomy," "snout-shifting," "axle-brace maxillary raking," "mandibular raking," and "single-axle maxillary raking," respectively. The lack of synapomorphy among scolecophidians is inconsistent with the notion of scolecophidians representing an ancestral snake condition, and instead reflects a hypothesis of the independent evolution of fossoriality, miniaturization, and "microstomy" in each scolecophidian lineage. We ultimately emphasize that a rigorous approach to comparative anatomy is necessary in constructing evolutionary hypotheses that accurately reflect biological reality.},
language = {en}
}
@misc{MalchowBocediPalmeretal.2021,
author = {Malchow, Anne-Kathleen and Bocedi, Greta and Palmer, Stephen C. F. and Travis, Justin M. J. and Zurell, Damaris},
title = {RangeShiftR: an R package for individual-based simulation of spatial eco-evolutionary dynamics and speciesu0027 responses to environmental changes},
series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
number = {10},
issn = {1866-8372},
doi = {10.25932/publishup-52397},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-523979},
pages = {12},
year = {2021},
abstract = {Reliably modelling the demographic and distributional responses of a species to environmental changes can be crucial for successful conservation and management planning. Process-based models have the potential to achieve this goal, but so far they remain underused for predictions of species' distributions. Individual-based models offer the additional capability to model inter-individual variation and evolutionary dynamics and thus capture adaptive responses to environmental change. We present RangeShiftR, an R implementation of a flexible individual-based modelling platform which simulates eco-evolutionary dynamics in a spatially explicit way. The package provides flexible and fast simulations by making the software RangeShifter available for the widely used statistical programming platform R. The package features additional auxiliary functions to support model specification and analysis of results. We provide an outline of the package's functionality, describe the underlying model structure with its main components and present a short example. RangeShiftR offers substantial model complexity, especially for the demographic and dispersal processes. It comes with elaborate tutorials and comprehensive documentation to facilitate learning the software and provide help at all levels. As the core code is implemented in C++, the computations are fast. The complete source code is published under a public licence, making adaptations and contributions feasible. The RangeShiftR package facilitates the application of individual-based and mechanistic modelling to eco-evolutionary questions by operating a flexible and powerful simulation model from R. It allows effortless interoperation with existing packages to create streamlined workflows that can include data preparation, integrated model specification and results analysis. Moreover, the implementation in R strengthens the potential for coupling RangeShiftR with other models.},
language = {en}
}
@article{BlanchardAbeykoonFrostetal.2021,
author = {Blanchard, Ingrid and Abeykoon, Sumith and Frost, Daniel J. and Rubie, David C.},
title = {Sulfur content at sulfide saturation of peridotitic melt at upper mantle conditions},
series = {American mineralogist : an international journal of earth and planetary materials / Mineralogical Society of America},
volume = {106},
journal = {American mineralogist : an international journal of earth and planetary materials / Mineralogical Society of America},
number = {11},
publisher = {Mineralogical Society of America},
address = {Washington, DC [u.a.]},
issn = {0003-004X},
doi = {10.2138/am-2021-7649},
pages = {1835 -- 1843},
year = {2021},
abstract = {The concentration of sulfur that can be dissolved in a silicate liquid is of fundamental importance because it is closely associated with several major Earth-related processes. Considerable effort has been made to understand the interplay between the effects of silicate melt composition and its capac-ity to retain sulfur, but the dependence on pressure and temperature is mostly based on experiments performed at pressures and temperatures below 6 GPa and 2073 K. Here we present a study of the effects of pressure and temperature on sulfur content at sulfide saturation of a peridotitic liquid. We performed 14 multi-anvil experiments using a peridotitic starting composition, and we produced 25 new measurements at conditions ranging from 7 to 23 GPa and 2173 to 2623 K. We analyzed the recovered samples using both electron microprobe and laser ablation ICP-MS. We compiled our data together with previously published data that were obtained at lower P-T conditions and with various silicate melt compositions. We present a new model based on this combined data set that encompasses the entire range of upper mantle pressure-temperature conditions, along with the effect of a wide range of silicate melt compositions. Our findings are consistent with earlier work based on extrapolation from lower-pressure and lower-temperature experiments and show a decrease of sulfur content at sulfide saturation (SCSS) with increasing pressure and an increase of SCSS with increasing temperature. We have extrapolated our results to pressure-temperature conditions of the Earth's primitive magma ocean, and show that FeS will exsolve from the molten silicate and can effectively be extracted to the core by a process that has been termed the "Hadean Matte." We also discuss briefly the implications of our results for the lunar magma ocean.},
language = {en}
}
@article{DiluisoWalkManychetal.2021,
author = {Diluiso, Francesca and Walk, Paula and Manych, Niccolo and Cerutti, Nicola and Chipiga, Vladislav and Workman, Annabelle and Ayas, Ceren and Cui, Ryna Yiyun and Cui, Diyang and Song, Kaihui and Banisch, Lucy A. and Moretti, Nikolaj and Callaghan, Max W. and Clarke, Leon and Creutzig, Felix and Hilaire, Jerome and Jotzo, Frank and Kalkuhl, Matthias and Lamb, William F. and L{\"o}schel, Andreas and M{\"u}ller-Hansen, Finn and Nemet, Gregory F. and Oei, Pao-Yu and Sovacool, Benjamin K. and Steckel, Jan Christoph and Thomas, Sebastian and Wiseman, John and Minx, Jan C.},
title = {Coal transitions - part 1},
series = {Environmental research letters},
volume = {16},
journal = {Environmental research letters},
number = {11},
publisher = {Institute of Physics Publishing (IOP)},
address = {Bristol},
issn = {1748-9326},
doi = {10.1088/1748-9326/ac1b58},
pages = {40},
year = {2021},
abstract = {A rapid coal phase-out is needed to meet the goals of the Paris Agreement, but is hindered by serious challenges ranging from vested interests to the risks of social disruption. To understand how to organize a global coal phase-out, it is crucial to go beyond cost-effective climate mitigation scenarios and learn from the experience of previous coal transitions. Despite the relevance of the topic, evidence remains fragmented throughout different research fields, and not easily accessible. To address this gap, this paper provides a systematic map and comprehensive review of the literature on historical coal transitions. We use computer-assisted systematic mapping and review methods to chart and evaluate the available evidence on historical declines in coal production and consumption. We extracted a dataset of 278 case studies from 194 publications, covering coal transitions in 44 countries and ranging from the end of the 19th century until 2021. We find a relatively recent and rapidly expanding body of literature reflecting the growing importance of an early coal phase-out in scientific and political debates. Previous evidence has primarily focused on the United Kingdom, the United States, and Germany, while other countries that experienced large coal declines, like those in Eastern Europe, are strongly underrepresented. An increasing number of studies, mostly published in the last 5 years, has been focusing on China. Most of the countries successfully reducing coal dependency have undergone both demand-side and supply-side transitions. This supports the use of policy approaches targeting both demand and supply to achieve a complete coal phase-out. From a political economy perspective, our dataset highlights that most transitions are driven by rising production costs for coal, falling prices for alternative energies, or local environmental concerns, especially regarding air pollution. The main challenges for coal-dependent regions are structural change transformations, in particular for industry and labor. Rising unemployment is the most largely documented outcome in the sample. Policymakers at multiple levels are instrumental in facilitating coal transitions. They rely mainly on regulatory instruments to foster the transitions and compensation schemes or investment plans to deal with their transformative processes. Even though many models suggest that coal phase-outs are among the low-hanging fruits on the way to climate neutrality and meeting the international climate goals, our case studies analysis highlights the intricate political economy at work that needs to be addressed through well-designed and just policies.},
language = {en}
}
@article{MalchowBocediPalmeretal.2021,
author = {Malchow, Anne-Kathleen and Bocedi, Greta and Palmer, Stephen C. F. and Travis, Justin M. J. and Zurell, Damaris},
title = {RangeShiftR},
series = {Ecography : pattern and diversity in ecology / Nordic Ecologic Society Oikos},
volume = {44},
journal = {Ecography : pattern and diversity in ecology / Nordic Ecologic Society Oikos},
number = {10},
publisher = {Wiley-Blackwell},
address = {Oxford [u.a.]},
issn = {1600-0587},
doi = {10.1111/ecog.05689},
pages = {1443 -- 1452},
year = {2021},
abstract = {Reliably modelling the demographic and distributional responses of a species to environmental changes can be crucial for successful conservation and management planning. Process-based models have the potential to achieve this goal, but so far they remain underused for predictions of species' distributions. Individual-based models offer the additional capability to model inter-individual variation and evolutionary dynamics and thus capture adaptive responses to environmental change. We present RangeShiftR, an R implementation of a flexible individual-based modelling platform which simulates eco-evolutionary dynamics in a spatially explicit way. The package provides flexible and fast simulations by making the software RangeShifter available for the widely used statistical programming platform R. The package features additional auxiliary functions to support model specification and analysis of results. We provide an outline of the package's functionality, describe the underlying model structure with its main components and present a short example. RangeShiftR offers substantial model complexity, especially for the demographic and dispersal processes. It comes with elaborate tutorials and comprehensive documentation to facilitate learning the software and provide help at all levels. As the core code is implemented in C++, the computations are fast. The complete source code is published under a public licence, making adaptations and contributions feasible. The RangeShiftR package facilitates the application of individual-based and mechanistic modelling to eco-evolutionary questions by operating a flexible and powerful simulation model from R. It allows effortless interoperation with existing packages to create streamlined workflows that can include data preparation, integrated model specification and results analysis. Moreover, the implementation in R strengthens the potential for coupling RangeShiftR with other models.},
language = {en}
}