@phdthesis{Heise2014, author = {Heise, Arvid}, title = {Data cleansing and integration operators for a parallel data analytics platform}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-77100}, school = {Universit{\"a}t Potsdam}, pages = {ii, 179}, year = {2014}, abstract = {The data quality of real-world datasets need to be constantly monitored and maintained to allow organizations and individuals to reliably use their data. Especially, data integration projects suffer from poor initial data quality and as a consequence consume more effort and money. Commercial products and research prototypes for data cleansing and integration help users to improve the quality of individual and combined datasets. They can be divided into either standalone systems or database management system (DBMS) extensions. On the one hand, standalone systems do not interact well with DBMS and require time-consuming data imports and exports. On the other hand, DBMS extensions are often limited by the underlying system and do not cover the full set of data cleansing and integration tasks. We overcome both limitations by implementing a concise set of five data cleansing and integration operators on the parallel data analytics platform Stratosphere. We define the semantics of the operators, present their parallel implementation, and devise optimization techniques for individual operators and combinations thereof. Users specify declarative queries in our query language METEOR with our new operators to improve the data quality of individual datasets or integrate them to larger datasets. By integrating the data cleansing operators into the higher level language layer of Stratosphere, users can easily combine cleansing operators with operators from other domains, such as information extraction, to complex data flows. Through a generic description of the operators, the Stratosphere optimizer reorders operators even from different domains to find better query plans. As a case study, we reimplemented a part of the large Open Government Data integration project GovWILD with our new operators and show that our queries run significantly faster than the original GovWILD queries, which rely on relational operators. Evaluation reveals that our operators exhibit good scalability on up to 100 cores, so that even larger inputs can be efficiently processed by scaling out to more machines. Finally, our scripts are considerably shorter than the original GovWILD scripts, which results in better maintainability of the scripts.}, language = {en} } @phdthesis{Pussak2014, author = {Pussak, Marcin}, title = {Seismic characterization of geothermal reservoirs by application of the common-reflection-surface stack method and attribute analysis}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-77565}, school = {Universit{\"a}t Potsdam}, pages = {viii, 140}, year = {2014}, abstract = {An important contribution of geosciences to the renewable energy production portfolio is the exploration and utilization of geothermal resources. For the development of a geothermal project at great depths a detailed geological and geophysical exploration program is required in the first phase. With the help of active seismic methods high-resolution images of the geothermal reservoir can be delivered. This allows potential transport routes for fluids to be identified as well as regions with high potential of heat extraction to be mapped, which indicates favorable conditions for geothermal exploitation. The presented work investigates the extent to which an improved characterization of geothermal reservoirs can be achieved with the new methods of seismic data processing. The summations of traces (stacking) is a crucial step in the processing of seismic reflection data. The common-reflection-surface (CRS) stacking method can be applied as an alternative for the conventional normal moveout (NMO) or the dip moveout (DMO) stack. The advantages of the CRS stack beside an automatic determination of stacking operator parameters include an adequate imaging of arbitrarily curved geological boundaries, and a significant increase in signal-to-noise (S/N) ratio by stacking far more traces than used in a conventional stack. A major innovation I have shown in this work is that the quality of signal attributes that characterize the seismic images can be significantly improved by this modified type of stacking in particular. Imporoved attribute analysis facilitates the interpretation of seismic images and plays a significant role in the characterization of reservoirs. Variations of lithological and petro-physical properties are reflected by fluctuations of specific signal attributes (eg. frequency or amplitude characteristics). Its further interpretation can provide quality assessment of the geothermal reservoir with respect to the capacity of fluids within a hydrological system that can be extracted and utilized. The proposed methodological approach is demonstrated on the basis on two case studies. In the first example, I analyzed a series of 2D seismic profile sections through the Alberta sedimentary basin on the eastern edge of the Canadian Rocky Mountains. In the second application, a 3D seismic volume is characterized in the surroundings of a geothermal borehole, located in the central part of the Polish basin. Both sites were investigated with the modified and improved stacking attribute analyses. The results provide recommendations for the planning of future geothermal plants in both study areas.}, language = {en} } @phdthesis{Conrad2014, author = {Conrad, Claudia}, title = {Open cluster groups and complexes}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-77605}, school = {Universit{\"a}t Potsdam}, pages = {xii, 172}, year = {2014}, abstract = {It is generally agreed upon that stars typically form in open clusters and stellar associations, but little is known about the structure of the open cluster system. Do open clusters and stellar associations form isolated or do they prefer to form in groups and complexes? Open cluster groups and complexes could verify star forming regions to be larger than expected, which would explain the chemical homogeneity over large areas in the Galactic disk. They would also define an additional level in the hierarchy of star formation and could be used as tracers for the scales of fragmentation in giant molecular clouds? Furthermore, open cluster groups and complexes could affect Galactic dynamics and should be considered in investigations and simulations on the dynamical processes, such as radial migration, disc heating, differential rotation, kinematic resonances, and spiral structure. In the past decade there were a few studies on open cluster pairs (de La Fuente Marcos \& de La Fuente Marcos 2009a,b,c) and on open cluster groups and complexes (Piskunov et al. 2006). The former only considered spatial proximity for the identification of the pairs, while the latter also required tangential velocities to be similar for the members. In this work I used the full set of 6D phase-space information to draw a more detailed picture on these structures. For this purpose I utilised the most homogeneous cluster catalogue available, namely the Catalogue of Open Cluster Data (COCD; Kharchenko et al. 2005a,b), which contains parameters for 650 open clusters and compact associations, as well as for their uniformly selected members. Additional radial velocity (RV) and metallicity ([M/H]) information on the members were obtained from the RAdial Velocity Experiment (RAVE; Steinmetz et al. 2006; Kordopatis et al. 2013) for 110 and 81 clusters, respectively. The RAVE sample was cleaned considering quality parameters and flags provided by RAVE (Matijevič et al. 2012; Kordopatis et al. 2013). To ensure that only real members were included for the mean values, also the cluster membership, as provided by Kharchenko et al. (2005a,b), was considered for the stars cross-matched in RAVE. 6D phase-space information could be derived for 432 out of the 650 COCD objects and I used an adaption of the Friends-of-Friends algorithm, as used in cosmology, to identify potential groupings. The vast majority of the 19 identified groupings were pairs, but I also found four groups of 4-5 members and one complex with 15 members. For the verification of the identified structures, I compared the results to a randomly selected subsample of the catalogue for the Milky Way global survey of Star Clusters (MWSC; Kharchenko et al. 2013), which became available recently, and was used as reference sample. Furthermore, I implemented Monte-Carlo simulations with randomised samples created from two distinguished input distributions for the spatial and velocity parameters. On the one hand, assuming a uniform distribution in the Galactic disc and, on the other hand, assuming the COCD data distributions to be representative for the whole open cluster population. The results suggested that the majority of identified pairs are rather by chance alignments, but the groups and the complex seemed to be genuine. A comparison of my results to the pairs, groups and complexes proposed in the literature yielded a partial overlap, which was most likely because of selection effects and different parameters considered. This is another verification for the existence of such structures. The characteristics of the found groupings favour that members of an open cluster grouping originate from a common giant molecular cloud and formed in a single, but possibly sequential, star formation event. Moreover, the fact that the young open cluster population showed smaller spatial separations between nearest neighbours than the old cluster population indicated that the lifetime of open cluster groupings is most likely comparable to that of the Galactic open cluster population itself. Still even among the old open clusters I could identify groupings, which suggested that the detected structure could be in some cases more long lived as one might think. In this thesis I could only present a pilot study on structures in the Galactic open cluster population, since the data sample used was highly incomplete. For further investigations a far more complete sample would be required. One step in this direction would be to use data from large current surveys, like SDSS, RAVE, Gaia-ESO and VVV, as well as including results from studies on individual clusters. Later the sample can be completed by data from upcoming missions, like Gaia and 4MOST. Future studies using this more complete open cluster sample will reveal the effect of open cluster groupings on star formation theory and their significance for the kinematics, dynamics and evolution of the Milky Way, and thereby of spiral galaxies.}, language = {en} } @phdthesis{Jueppner2014, author = {J{\"u}ppner, Jessica}, title = {Characterization of metabolomic dynamics in synchronized Chlamydomonas reinhardtii cell cultures and the impact of TOR inhibition on cell cycle, proliferation and growth}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-76923}, school = {Universit{\"a}t Potsdam}, pages = {VI, 153}, year = {2014}, abstract = {The adaptation of cell growth and proliferation to environmental changes is essential for the surviving of biological systems. The evolutionary conserved Ser/Thr protein kinase "Target of Rapamycin" (TOR) has emerged as a major signaling node that integrates the sensing of numerous growth signals to the coordinated regulation of cellular metabolism and growth. Although the TOR signaling pathway has been widely studied in heterotrophic organisms, the research on TOR in photosynthetic eukaryotes has been hampered by the reported land plant resistance to rapamycin. Thus, the finding that Chlamydomonas reinhardtii is sensitive to rapamycin, establish this unicellular green alga as a useful model system to investigate TOR signaling in photosynthetic eukaryotes. The observation that rapamycin does not fully arrest Chlamydomonas growth, which is different from observations made in other organisms, prompted us to investigate the regulatory function of TOR in Chlamydomonas in context of the cell cycle. Therefore, a growth system that allowed synchronously growth under widely unperturbed cultivation in a fermenter system was set up and the synchronized cells were characterized in detail. In a highly resolved kinetic study, the synchronized cells were analyzed for their changes in cytological parameters as cell number and size distribution and their starch content. Furthermore, we applied mass spectrometric analysis for profiling of primary and lipid metabolism. This system was then used to analyze the response dynamics of the Chlamydomonas metabolome and lipidome to TOR-inhibition by rapamycin The results show that TOR inhibition reduces cell growth, delays cell division and daughter cell release and results in a 50\% reduced cell number at the end of the cell cycle. Consistent with the growth phenotype we observed strong changes in carbon and nitrogen partitioning in the direction of rapid conversion into carbon and nitrogen storage through an accumulation of starch, triacylglycerol and arginine. Interestingly, it seems that the conversion of carbon into triacylglycerol occurred faster than into starch after TOR inhibition, which may indicate a more dominant role of TOR in the regulation of TAG biosynthesis than in the regulation of starch. This study clearly shows, for the first time, a complex picture of metabolic and lipidomic dynamically changes during the cell cycle of Chlamydomonas reinhardtii and furthermore reveals a complex regulation and adjustment of metabolite pools and lipid composition in response to TOR inhibition.}, language = {en} } @phdthesis{Scheinemann2014, author = {Scheinemann, Hendrik Alexander}, title = {Hygienisierung von Rinderg{\"u}lle und Kl{\"a}rschl{\"a}mmen mittels milchsaurer Fermentation}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-77949}, school = {Universit{\"a}t Potsdam}, pages = {xviii, 172}, year = {2014}, abstract = {Tierische und menschliche F{\"a}kalien aus Landwirtschaft und Haushalten enthalten zahlreiche obligat und opportunistisch pathogene Mikroorganismen, deren Konzentration u. a. je nach Gesundheitszustand der betrachteten Gruppe schwankt. Neben den Krankheitserregern enthalten F{\"a}kalien aber auch essentielle Pflanzenn{\"a}hrstoffe (276) und dienen seit Jahrtausenden (63) als D{\"u}nger f{\"u}r Feldfr{\"u}chte. Mit der unbedarften Verwendung von pathogenbelastetem F{\"a}kald{\"u}nger steigt jedoch auch das Risiko einer Infektion von Mensch und Tier. Diese Gefahr erh{\"o}ht sich mit der globalen Vernetzung der Landwirtschaft, z. B. durch den Import von kontaminierten Futter- bzw. Lebensmitteln (29). Die vorliegende Arbeit stellt die milchsaure Fermentation von Rinderg{\"u}lle und Kl{\"a}rschlamm als alternative Hygienisierungsmethode gegen{\"u}ber der Pasteurisation in Biogasanlagen bzw. gebr{\"a}uchlichen Kompostierung vor. Dabei wird ein Abfall der Gram-negativen Bakterienflora sowie der Enterokokken, Schimmel- und Hefepilze unter die Nachweisgrenze von 3 log10KbE/g beobachtet, gleichzeitig steigt die Konzentration der Lactobacillaceae um das Tausendfache. Dar{\"u}ber hinaus wird gezeigt, dass pathogene Bakterien wie Staphylococcus aureus, Salmonella spp., Listeria monocytogenes, EHEC O:157 und vegetative Clostridum perfringens-Zellen innerhalb von 3 Tagen inaktiviert werden. Die Inaktivierung von ECBO-Viren und Spulwurmeiern erfolgt innerhalb von 7 bzw. 56 Tagen. Zur Aufkl{\"a}rung der Ursache der beobachteten Hygienisierung wurde das fermentierte Material auf fl{\"u}chtige Fetts{\"a}uren sowie pH-Wert{\"a}nderungen untersucht. Es konnte festgestellt werden, dass die gemessenen Werte nicht die alleinige Ursache f{\"u}r das Absterben der Erreger sind, vielmehr wird eine zus{\"a}tzliche bakterizide Wirkung durch eine mutmaßliche Bildung von Bakteriozinen in Betracht gezogen. Die parasitizide Wirkung wird auf die physikalischen Bedingungen der Fermentation zur{\"u}ckgef{\"u}hrt. Die methodischen Grundlagen basieren auf Analysen mittels zahlreicher klassisch-kultureller Verfahren, wie z. B. der Lebendkeimzahlbestimmung. Dar{\"u}ber hinaus findet die MALDI-TOF-Massenspektrometrie und die klassische PCR in Kombination mit der Gradienten-Gelelektrophorese Anwendung, um kultivierbare Bakterienfloren zu beschreiben bzw. nicht kultivierbare Bakterienfloren stichprobenartig zu erfassen. Neben den Aspekten der Hygienisierung wird zudem die Eignung der Methode f{\"u}r die landwirtschaftliche Nutzung ber{\"u}cksichtigt. Dies findet sich insbesondere in der Komposition des zu fermentierenden Materials wieder, welches f{\"u}r die verst{\"a}rkte Humusakkumulation im Ackerboden optimiert wurde. Dar{\"u}ber hinaus wird die Masseverlustbilanz w{\"a}hrend der milchsauren Fermentation mit denen der Kompostierung sowie der Verarbeitung in der Biogasanlage verglichen und als positiv bewertet, da sie mit insgesamt 2,45 \% sehr deutlich unter den bisherigen Alternativen liegt (73, 138, 458). Weniger Verluste an organischem Material w{\"a}hrend der Hygienisierung f{\"u}hren zu einer gr{\"o}ßeren verwendbaren D{\"u}ngermenge, die auf Grund ihres organischen Ursprungs zu einer Verst{\"a}rkung des Humusanteiles im Ackerboden beitragen kann (56, 132).}, language = {de} } @phdthesis{Schmidl2014, author = {Schmidl, Ricarda}, title = {Empirical essays on job search behavior, active labor market policies, and propensity score balancing methods}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-71145}, school = {Universit{\"a}t Potsdam}, year = {2014}, abstract = {In Chapter 1 of the dissertation, the role of social networks is analyzed as an important determinant in the search behavior of the unemployed. Based on the hypothesis that the unemployed generate information on vacancies through their social network, search theory predicts that individuals with large social networks should experience an increased productivity of informal search, and reduce their search in formal channels. Due to the higher productivity of search, unemployed with a larger network are also expected to have a higher reservation wage than unemployed with a small network. The model-theoretic predictions are tested and confirmed empirically. It is found that the search behavior of unemployed is significantly affected by the presence of social contacts, with larger networks implying a stronger substitution away from formal search channels towards informal channels. The substitution is particularly pronounced for passive formal search methods, i.e., search methods that generate rather non-specific types of job offer information at low relative cost. We also find small but significant positive effects of an increase of the network size on the reservation wage. These results have important implications on the analysis of the job search monitoring or counseling measures that are usually targeted at formal search only. Chapter 2 of the dissertation addresses the labor market effects of vacancy information during the early stages of unemployment. The outcomes considered are the speed of exit from unemployment, the effects on the quality of employment and the short-and medium-term effects on active labor market program (ALMP) participation. It is found that vacancy information significantly increases the speed of entry into employment; at the same time the probability to participate in ALMP is significantly reduced. Whereas the long-term reduction in the ALMP arises in consequence of the earlier exit from unemployment, we also observe a short-run decrease for some labor market groups which suggest that caseworker use high and low intensity activation measures interchangeably which is clearly questionable from an efficiency point of view. For unemployed who find a job through vacancy information we observe a small negative effect on the weekly number of hours worked. In Chapter 3, the long-term effects of participation in ALMP are assessed for unemployed youth under 25 years of age. Complementary to the analysis in Chapter 2, the effects of participation in time- and cost-intensive measures of active labor market policies are examined. In particular we study the effects of job creation schemes, wage subsidies, short-and long-term training measures and measures to promote the participation in vocational training. The outcome variables of interest are the probability to be in regular employment, and participation in further education during the 60 months following program entry. The analysis shows that all programs, except job creation schemes have positive and long-term effects on the employment probability of youth. In the short-run only short-term training measures generate positive effects, as long-term training programs and wage subsidies exhibit significant locking-in'' effects. Measures to promote vocational training are found to increase the probability of attending education and training significantly, whereas all other programs have either no or a negative effect on training participation. Effect heterogeneity with respect to the pre-treatment level education shows that young people with higher pre-treatment educational levels benefit more from participation most programs. However, for longer-term wage subsidies we also find strong positive effects for young people with low initial education levels. The relative benefit of training measures is higher in West than in East Germany. In the evaluation studies of Chapters 2 and 3 semi-parametric balancing methods of Propensity Score Matching (PSM) and Inverse Probability Weighting (IPW) are used to eliminate the effects of counfounding factors that influence both the treatment participation as well as the outcome variable of interest, and to establish a causal relation between program participation and outcome differences. While PSM and IPW are intuitive and methodologically attractive as they do not require parametric assumptions, the practical implementation may become quite challenging due to their sensitivity to various data features. Given the importance of these methods in the evaluation literature, and the vast number of recent methodological contributions in this field, Chapter 4 aims to reduce the knowledge gap between the methodological and applied literature by summarizing new findings of the empirical and statistical literature and practical guidelines for future applied research. In contrast to previous publications this study does not only focus on the estimation of causal effects, but stresses that the balancing challenge can and should be discussed independent of question of causal identification of treatment effects on most empirical applications. Following a brief outline of the practical implementation steps required for PSM and IPW, these steps are presented in detail chronologically, outlining practical advice for each step. Subsequently, the topics of effect estimation, inference, sensitivity analysis and the combination with parametric estimation methods are discussed. Finally, new extensions of the methodology and avenues for future research are presented.}, language = {en} } @phdthesis{Tietz2014, author = {Tietz, Marcel}, title = {Europ{\"a}isches Verwaltungsmanagement : Vergleich von Hauptst{\"a}dten neuer und alter Mitgliedsstaaten der EU am Beispiel der B{\"u}rgerdienste}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-72171}, school = {Universit{\"a}t Potsdam}, year = {2014}, abstract = {Im Rahmen der Dissertation wird die Anwendung und Wirkung von Kernelementen des New Public Management (NPM) am Beispiel der B{\"u}rgerdienste der sechs europ{\"a}ischen Hauptst{\"a}dte Berlin, Br{\"u}ssel, Kopenhagen, Madrid, Prag und Warschau analysiert. Hierbei steht der Vergleich von Hauptst{\"a}dten der MOE-Staaten mit Hauptst{\"a}dten alter EU-Mitgliedsstaaten im Vordergrund. Es wird die folgende Forschungshypothese untersucht: Die Verwaltungen in den Hauptst{\"a}dten der {\"o}stlichen Mitgliedsstaaten der EU haben in Folge der grunds{\"a}tzlichen gesellschaftlichen und politischen Umbr{\"u}che in den 1990er Jahren bedeutend mehr Kernelemente des NPM beim Neuaufbau ihrer {\"o}ffentlichen Verwaltungen eingef{\"u}hrt. Durch den folgerichtigen Aufbau kundenorientierter und moderner Verwaltungen sowie der strikten Anwendung der Kernelemente des New Public Management arbeiten die B{\"u}rgerdienste in den Hauptst{\"a}dten {\"o}stlicher EU-Mitgliedsstaaten effizienter und wirkungsvoller als vergleichbare B{\"u}rgerdienste in den Hauptst{\"a}dten westlicher EU-Mitgliedsstaaten. Zur {\"U}berpr{\"u}fung der Forschungshypothese werden die Vergleichsst{\"a}dte zun{\"a}chst den entsprechenden Rechts- und Verwaltungstraditionen (kontinentaleurop{\"a}isch deutsch, napoleonisch und skandinavisch) zugeordnet und bez{\"u}glich ihrer Ausgangslage zum Aufbau einer modernen Verwaltung (Westeurop{\"a}ische Verwaltung, Wiedervereinigungsverwaltung und Transformations-verwaltung) kategorisiert. Im Anschluss werden die institutionellen Voraussetzungen hinterfragt, was die deskriptive Darstellung der Stadt- und Verwaltungsgeschichte sowie die Untersuchung von organisatorischen Strukturen der B{\"u}rgerdienste, die Anwendung der NPM-Instrumente als auch die Innen- und Außenperspektive des NPM umfasst. Es wird festgestellt, ob und in welcher Form die B{\"u}rgerdienste der Vergleichsst{\"a}dte die Kernelemente des NPM anwenden. Im Anschluss werden die Vergleichsst{\"a}dte bez{\"u}glich der Anwendung der Kernelemente miteinander verglichen, wobei der Fokus auf dem pers{\"o}nlichen Vertriebsweg und der Kundenorientierung liegt. Der folgende Teil der Dissertation befasst sich mit dem Output der B{\"u}rgerdienste, der auf operative Resultate untersucht und verglichen wird. Hierbei stellt sich insbesondere die Frage nach den Leistungsmengen und der Produktivit{\"a}t des Outputs. Es werden aber auch die Ergebnisse von Verwaltungsprozessen untersucht, insbesondere in Bezug auf die Kundenorientierung. Hierf{\"u}r wird ein Effizienzvergleich der B{\"u}rgerdienste in den Vergleichsst{\"a}dten anhand einer relativen Effizienzmessung und der Free Disposal Hull (FDH)-Methode nach Bouckaert durchgef{\"u}hrt. Es ist eine Konzentration auf popul{\"a}re Dienstleistungen aus dem Portfolio der B{\"u}rgerdienste notwendig. Daher werden die vergleichbaren Dienstleistungen Melde-, Personalausweis-, F{\"u}hrerschein- und Reisepass-angelegenheiten unter Einbeziehung des Vollzeit{\"a}quivalents zur Berechnung der Effizienz der B{\"u}rgerdienste herangezogen. Hierf{\"u}r werden Daten aus den Jahren 2009 bis 2011 genutzt, die teilweise aus verwaltungsinternen Datenbanken stammen. Anschließend wird der Versuch unternommen, den Outcome in die Effizienzanalyse der B{\"u}rgerdienste einfließen zu lassen. In diesem Zusammenhang wird die Anwendbarkeit von verschiedenen erweiterten Best-Practice-Verfahren und auch eine Erweiterung der relativen Effizienzmessung und der FDH-Methode gepr{\"u}ft. Als Gesamtfazit der Dissertation kann festgehalten werden, dass die B{\"u}rgerdienste in den untersuchten Hauptst{\"a}dten der MOE-Staaten nicht mehr Kernelemente des NPM anwenden, als die Hauptst{\"a}dte der westlichen Mitgliedsstaaten der EU. Im Gegenteil wendet Prag deutlich weniger NPM-Instrumente als andere Vergleichsst{\"a}dte an, wohingegen Warschau zwar viele NPM-Instrumente anwendet, jedoch immer von einer westeurop{\"a}ischen Vergleichsstadt {\"u}bertroffen wird. Auch die Hypothese, dass die B{\"u}rgerdienste in den Hauptst{\"a}dten der MOE-Staaten effizienter arbeiten als vergleichbare B{\"u}rgerdienste in den Hauptst{\"a}dten westlicher EU-Mitgliedsstaaten wurde durch die Dissertation entkr{\"a}ftet. Das Gegenteil ist der Fall, da Prag und Warschau im Rahmen des Effizienzvergleichs lediglich durchschnittliche oder schlechte Performances aufweisen. Die aufgestellte Hypothese ist durch die Forschungsergebnisse widerlegt, lediglich das gute Abschneiden der Vergleichsstadt Warschau bei der Anwendungsanalyse kann einen Teil der These im gewissen Umfang best{\"a}tigen.}, language = {de} } @phdthesis{Lorey2014, author = {Lorey, Johannes}, title = {What's in a query : analyzing, predicting, and managing linked data access}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-72312}, school = {Universit{\"a}t Potsdam}, year = {2014}, abstract = {The term Linked Data refers to connected information sources comprising structured data about a wide range of topics and for a multitude of applications. In recent years, the conceptional and technical foundations of Linked Data have been formalized and refined. To this end, well-known technologies have been established, such as the Resource Description Framework (RDF) as a Linked Data model or the SPARQL Protocol and RDF Query Language (SPARQL) for retrieving this information. Whereas most research has been conducted in the area of generating and publishing Linked Data, this thesis presents novel approaches for improved management. In particular, we illustrate new methods for analyzing and processing SPARQL queries. Here, we present two algorithms suitable for identifying structural relationships between these queries. Both algorithms are applied to a large number of real-world requests to evaluate the performance of the approaches and the quality of their results. Based on this, we introduce different strategies enabling optimized access of Linked Data sources. We demonstrate how the presented approach facilitates effective utilization of SPARQL endpoints by prefetching results relevant for multiple subsequent requests. Furthermore, we contribute a set of metrics for determining technical characteristics of such knowledge bases. To this end, we devise practical heuristics and validate them through thorough analysis of real-world data sources. We discuss the findings and evaluate their impact on utilizing the endpoints. Moreover, we detail the adoption of a scalable infrastructure for improving Linked Data discovery and consumption. As we outline in an exemplary use case, this platform is eligible both for processing and provisioning the corresponding information.}, language = {en} } @phdthesis{Sarrar2014, author = {Sarrar, Lea}, title = {Kognitive Funktionen bei adoleszenten Patienten mit Anorexia nervosa und unipolaren Affektiven St{\"o}rungen}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-72439}, school = {Universit{\"a}t Potsdam}, year = {2014}, abstract = {Anorexia nervosa und unipolare Affektive St{\"o}rungen stellen h{\"a}ufige und schwerwiegende kinder- und jugendpsychiatrische St{\"o}rungsbilder dar, deren Pathogenese bislang nicht vollst{\"a}ndig entschl{\"u}sselt ist. Verschiedene Studien zeigen bei erwachsenen Patienten gravierende Auff{\"a}lligkeiten in den kognitiven Funktionen. Dahingegen scheinen bei adoleszenten Patienten lediglich leichtere Einschr{\"a}nkungen in den kognitiven Funktionen vorzuliegen. Die Pr{\"a}valenz der Anorexia nervosa und unipolaren Affektiven St{\"o}rung ist mit Beginn der Adoleszenz deutlich erh{\"o}ht. Es ist anzunehmen, dass kognitive Dysfunktionen, die sich bereits in diesem Alter abzeichnen, den weiteren Krankheitsverlauf bis in das Erwachsenenalter, die Behandlungsergebnisse und die Prognose maßgeblich beeintr{\"a}chtigen k{\"o}nnten. Zudem ist von einem h{\"o}heren Chronifizierungsrisiko auszugehen. In der vorliegenden Arbeit wurden daher kognitive Funktionen bei adoleszenten Patientinnen mit Anorexia nervosa sowie Patienten mit unipolaren Affektiven St{\"o}rungen untersucht. Die {\"U}berpr{\"u}fung der kognitiven Funktionen bei Patientinnen mit Anorexia nervosa erfolgte vor und nach Gewichtszunahme. Weiterhin wurden zugrundeliegende biologische Mechanismen {\"u}berpr{\"u}ft. Zudem wurde die Spezifit{\"a}t kognitiver Dysfunktionen f{\"u}r beide St{\"o}rungsbilder untersucht und bei Patienten mit unipolaren Affektiven St{\"o}rungen geschlechtsbezogene Unterschiede exploriert. Insgesamt gingen 47 Patientinnen mit Anorexia nervosa (mittleres Alter 16,3 + 1,6 Jahre), 39 Patienten mit unipolaren Affektiven St{\"o}rungen (mittleres Alter 15,5 + 1,3 Jahre) sowie 78 Kontrollprobanden (mittleres Alter 16,5 + 1,3 Jahre) in die Untersuchung ein. S{\"a}mtliche Studienteilnehmer durchliefen eine neuropsychologische Testbatterie, bestehend aus Verfahren zur {\"U}berpr{\"u}fung der kognitiven Flexibilit{\"a}t sowie visuellen und psychomotorischen Verarbeitungsgeschwindigkeit. Neben einem Intelligenzscreening wurden zudem das Ausmaß der depressiven Symptomatik sowie die allgemeine psychische Belastung erfasst. Die Ergebnisse legen nahe, dass bei adoleszenten Patientinnen mit Anorexia nervosa, sowohl im akut untergewichtigen Zustand als auch nach Gewichtszunahme, lediglich milde Beeintr{\"a}chtigungen in den kognitiven Funktionen vorliegen. Im akut untergewichtigen Zustand offenbarten sich deutliche Zusammenh{\"a}nge zwischen dem appetitregulierenden Peptid Agouti-related Protein und kognitiver Flexibilit{\"a}t, nicht jedoch zwischen Agouti-related Protein und visueller oder psychomotorischer Verarbeitungsgeschwindigkeit. Bei dem Vergleich von Anorexia nervosa und unipolaren Affektiven St{\"o}rungen pr{\"a}dizierte die Zugeh{\"o}rigkeit zu der Patientengruppe Anorexia nervosa ein Risiko f{\"u}r das Vorliegen kognitiver Dysfunktionen. Es zeigte sich zudem, dass adoleszente Patienten mit unipolaren Affektiven St{\"o}rungen lediglich in der psychomotorischen Verarbeitungsgeschwindigkeit tendenziell schw{\"a}chere Leistungen offenbarten als gesunde Kontrollprobanden. Es ergab sich jedoch ein genereller geschlechtsbezogener Vorteil f{\"u}r weibliche Probanden in der visuellen und psychomotorischen Verarbeitungsgeschwindigkeit. Die vorliegenden Befunde unterstreichen die Notwendigkeit der {\"U}berpr{\"u}fung kognitiver Funktionen bei adoleszenten Patienten mit Anorexia nervosa sowie unipolaren Affektiven St{\"o}rungen in der klinischen Routinediagnostik. Die Patienten k{\"o}nnten von spezifischen Therapieprogrammen profitieren, die Beeintr{\"a}chtigungen in den kognitiven Funktionen mildern bzw. pr{\"a}ventiv behandeln.}, language = {de} } @phdthesis{Bamberg2014, author = {Bamberg, Marlene}, title = {Planetary mapping tools applied to floor-fractured craters on Mars}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-72104}, school = {Universit{\"a}t Potsdam}, year = {2014}, abstract = {Planetary research is often user-based and requires considerable skill, time, and effort. Unfortunately, self-defined boundary conditions, definitions, and rules are often not documented or not easy to comprehend due to the complexity of research. This makes a comparison to other studies, or an extension of the already existing research, complicated. Comparisons are often distorted, because results rely on different, not well defined, or even unknown boundary conditions. The purpose of this research is to develop a standardized analysis method for planetary surfaces, which is adaptable to several research topics. The method provides a consistent quality of results. This also includes achieving reliable and comparable results and reducing the time and effort of conducting such studies. A standardized analysis method is provided by automated analysis tools that focus on statistical parameters. Specific key parameters and boundary conditions are defined for the tool application. The analysis relies on a database in which all key parameters are stored. These databases can be easily updated and adapted to various research questions. This increases the flexibility, reproducibility, and comparability of the research. However, the quality of the database and reliability of definitions directly influence the results. To ensure a high quality of results, the rules and definitions need to be well defined and based on previously conducted case studies. The tools then produce parameters, which are obtained by defined geostatistical techniques (measurements, calculations, classifications). The idea of an automated statistical analysis is tested to proof benefits but also potential problems of this method. In this study, I adapt automated tools for floor-fractured craters (FFCs) on Mars. These impact craters show a variety of surface features, occurring in different Martian environments, and having different fracturing origins. They provide a complex morphological and geological field of application. 433 FFCs are classified by the analysis tools due to their fracturing process. Spatial data, environmental context, and crater interior data are analyzed to distinguish between the processes involved in floor fracturing. Related geologic processes, such as glacial and fluvial activity, are too similar to be separately classified by the automated tools. Glacial and fluvial fracturing processes are merged together for the classification. The automated tools provide probability values for each origin model. To guarantee the quality and reliability of the results, classification tools need to achieve an origin probability above 50 \%. This analysis method shows that 15 \% of the FFCs are fractured by intrusive volcanism, 20 \% by tectonic activity, and 43 \% by water \& ice related processes. In total, 75 \% of the FFCs are classified to an origin type. This can be explained by a combination of origin models, superposition or erosion of key parameters, or an unknown fracturing model. Those features have to be manually analyzed in detail. Another possibility would be the improvement of key parameters and rules for the classification. This research shows that it is possible to conduct an automated statistical analysis of morphologic and geologic features based on analysis tools. Analysis tools provide additional information to the user and are therefore considered assistance systems.}, language = {en} }