@inproceedings{Lebrenz2020,
  author    = {Lebrenz, Lucas},
  title     = {Nachwuchskolloquium zur Milit{\"a}rgeschichte},
  series = {Milit{\"a}rgeschichtliche Zeitschrift},
  volume    = {79},
  booktitle = {Milit{\"a}rgeschichtliche Zeitschrift},
  number    = {2},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {2193-2336},
  doi       = {10.1515/mgzs-2020-0073},
  pages     = {496 -- 502},
  year      = {2020},
  language  = {de}
}
@inproceedings{BergertKoesterKrasnovaetal.2020,
  author    = {Bergert, Cora and K{\"o}ster, Antonia and Krasnova, Hanna and Turel, Ofir},
  title     = {Missing out on life},
  series = {Proceedings of the 15th International Conference on Wirtschaftsinformatik : WI2020 Zentrale Tracks},
  booktitle = {Proceedings of the 15th International Conference on Wirtschaftsinformatik : WI2020 Zentrale Tracks},
  publisher = {GITO Verlag f{\"u}r Industrielle Informationstechnik und Organisation},
  address   = {Berlin},
  isbn      = {978-3-95545-335-0},
  doi       = {10.30844/wi_2020_f1-bergert},
  pages     = {568 -- 583},
  year      = {2020},
  abstract  = {Mobile devices have become an integral part of everyday life due to their portability. As literature shows, technology use is not only beneficial but also has dark sides, such as addiction. Parents face the need to balance perceived benefits and risks of children's exposure to mobile technologies. However, no study has uncovered what kind of benefits and concerns parents consider when implementing technology-related rules. We built on qualitative responses of 300 parents of children aged two to thirteen to explore concerns about, and perceived benefits of children's smartphone and tablet usage, as well as the rules parents have developed regarding technology use. Findings point to concerns regarding children's development, as well as benefits for both children and parents, and ultimately to new insights about mobile technology mediation. These results provide practical guidance for parents, physicians and mobile industry stakeholders, trying to ensure that children are acting responsibly with mobile technology.},
  language  = {en}
}
@inproceedings{BaumKoesterKrasnovaetal.2020,
  author    = {Baum, Katharina and K{\"o}ster, Antonia and Krasnova, Hanna and Tarafdar, Monideepa},
  title     = {Living in a world of plenty?},
  series = {Proceedings of the 28th European Conference on Information Systems (ECIS) : ECIS 2020 Research Papers},
  booktitle = {Proceedings of the 28th European Conference on Information Systems (ECIS) : ECIS 2020 Research Papers},
  publisher = {AIS Electronic Library (AISeL)},
  address   = {[Erscheinungsort nicht ermittelbar]},
  year      = {2020},
  abstract  = {Inequality in the distribution of economic wealth within populations has been rising steadily over the past century, having reached unprecedented highs in many Western societies. However, this development is not reflected in people's perceptions of wealth inequality, as the public tends to underestimate it. Research suggests that inequality estimates are derived from personal reference groups, which, as we propose, are expanded by social network site (SNS) use. As content on SNSs frequently revolves around events of consumption, signaling enhanced overall population wealth, this study tests the hypothesis that SNS use distorts inequality perceptions downward, i.e., increases the perception of societal equality. Responses of 534 survey participants in the United States confirm that SNS use negatively predicts perceived inequality. The relationship is stronger the more SNS users perceive the content they encounter online as real, supporting the assumption that observing other people's behavior online lowers estimates of nationwide wealth inequality. These findings provide novel insights on inequality misperceptions by suggesting individuals' SNS use as a new predictor of perceived wealth inequality.},
  language  = {en}
}
@inproceedings{SchenkeSchjeidePuescheletal.2020,
  author    = {Schenke, Maren and Schjeide, Brit-Maren and P{\"u}schel, Gerhard and Seeger, Bettina},
  title     = {Human motor neurons diffentiated from plutipotent stem cells as superior traged cells for botulinum neuotoxin potency testing},
  series = {Naunyn-Schmiedeberg's archives of pharmacology},
  volume    = {393},
  booktitle = {Naunyn-Schmiedeberg's archives of pharmacology},
  number    = {SUPPL 1},
  publisher = {Springer},
  address   = {Berlin ; Heidelberg},
  issn      = {0028-1298},
  doi       = {10.1007/s00210-020-01828-y},
  pages     = {10 -- 10},
  year      = {2020},
  language  = {en}
}
@inproceedings{GundlachKoesterKrasnovaetal.2020,
  author    = {Gundlach, Jana and K{\"o}ster, Antonia and Krasnova, Hanna and Tarafdar, Monideepa},
  title     = {How messy is your news feed},
  series = {Proceedings of the 28th European Conference on Information Systems (ECIS) : ECIS 2020 Research Papers},
  booktitle = {Proceedings of the 28th European Conference on Information Systems (ECIS) : ECIS 2020 Research Papers},
  publisher = {AIS Electronic Library (AISeL)},
  address   = {[Erscheinungsort nicht ermittelbar]},
  year      = {2020},
  abstract  = {Social Networking Sites (SNSs) are pervasive in our daily lives. However, emerging reports suggest that people are increasingly dissatisfied with their experience of SNSs News Feeds. Motivated by the cognitive load theory, the paper postulates that arrangement and presentation of information are important constituents of one's Facebook News Feed experience. Integrating these factors into the novel concept of 'perceived disorder', this paper hypothesizes that the perception of disorder elicited by the Facebook News Feed plays an important role in causing discontinuance intentions. Drawing on the Stressor-Strain-Outcome Model, we suggest that perceived disorder leads to SNS discontinuance intention and is partially mediated by SNS fatigue. The paper uses the responses of 268 Facebook users to investigate these relationships and introduces perceived disorder as a novel stressor. Besides adding to the existing body of literature, these insights are of relevance to internet service providers, policy makers and SNS users.},
  language  = {en}
}
@inproceedings{Haase2020,
  author    = {Haase, Jennifer},
  title     = {How games spoil creativity},
  series = {International conference of ISPIM / International Society for Professional Innovation Management : papers / Graduate School of Industrial Engineering and Management Science, Eindhoven University of Technology},
  booktitle = {International conference of ISPIM / International Society for Professional Innovation Management : papers / Graduate School of Industrial Engineering and Management Science, Eindhoven University of Technology},
  publisher = {International Society for Professional Innovation Management},
  address   = {Manchester},
  pages     = {1 -- 12},
  year      = {2020},
  abstract  = {The demand for a creative workforce is every growing and effective measures to improve individual creativity are searched for. This study analyzes the possibility to use games as a prime for a creative mindset. Two short entertainment games, plus a no-game-comparison condition were set up in three versions of an online-study, along with two creativity tasks and scales to assess the individual creative mindset (fixed-vs-growth, creative self-efficacy and affect). Results indicate priming effects of the games, but in the opposite intended direction: gaming diminished the creative test performances. Those playing the games reported more ideas in the open-ended creative problem task, but those answers were of less quality and they solved less closed-problem items compared to those not playing. An impact of further mindset differences could be ruled out.},
  language  = {en}
}
@inproceedings{VladovaRuedian2020,
  author    = {Vladova, Gergana and R{\"u}dian, Sylvio Leo},
  title     = {From learners to educators},
  series = {The future of education},
  volume    = {10},
  booktitle = {The future of education},
  publisher = {Pixel},
  address   = {Florenz},
  isbn      = {978-88-85813-87-8},
  issn      = {2420-9732},
  doi       = {10.26352/E618_2384-9509},
  pages     = {5},
  year      = {2020},
  abstract  = {The rapid growth of technology and its evolving potential to support the transformation of teaching and learning in post-secondary institutions is a major challenge to the basic understanding of both the university and the communities it serves. In higher education, the standard forms of learning and teaching are increasingly being challenged and a more comprehensive process of differentiation is taking place. Student-centered teaching methods are becoming increasingly important in course design and the role of the lecturer is changing from the knowledge mediator to moderator and learning companion. However, this is accelerating the need for strategically planned faculty support and a reassessment of the role of teaching and learning. Even though the benefits of experience-based learning approaches for the development of life skills are well known, most knowledge transfer is still realized through lectures in higher education. Teachers have the goal to design the curriculum, new assignments, and share insights into evolving pedagogy. Student engagement could be the most important factor in the learning success of university students, regardless of the university program or teaching format. Against this background, this article presents the development, application, and initial findings of an innovative learning concept. In this concept, students are allowed to deal with a scientific topic, but instead of a presentation and a written elaboration, their examination consists of developing an online course in terms of content, didactics, and concept to implement it in a learning environment, which is state of the art. The online courses include both self-created teaching material and interactive tasks. The courses are created to be available to other students as learning material after a review process and are thus incorporated into the curriculum.},
  language  = {en}
}
@inproceedings{DemarisGrišićHuisingaetal.2020,
  author    = {D{\´e}maris, Alise and Grišić, Ana-Marija and Huisinga, Wilhelm and Walter, Reinisch and Kloft, Charlotte},
  title     = {Evaluation of dosing strategies of anti-TNF alpha monoclonal antibodies using pharmacokinetic modelling and simulation},
  series = {Journal of Crohn's and Colitis},
  volume    = {14},
  booktitle = {Journal of Crohn's and Colitis},
  number    = {Supp. 1},
  publisher = {Oxford Univ. Press},
  address   = {Oxford},
  issn      = {1873-9946},
  doi       = {10.1093/ecco-jcc/jjz203.201},
  pages     = {S171 -- S172},
  year      = {2020},
  abstract  = {Background: Anti-TNFα monoclonal antibodies (mAbs) are a well-established treatment for patients with Crohn's disease (CD). However, subtherapeutic concentrations of mAbs have been related to a loss of response during the first year of therapy1. Therefore, an appropriate dosing strategy is crucial to prevent the underexposure of mAbs for those patients. The aim of our study was to assess the impact of different dosing strategies (fixed dose or body size descriptor adapted) on drug exposure and the target concentration attainment for two different anti-TNFα mAbs: infliximab (IFX, body weight (BW)-based dosing) and certolizumab pegol (CZP, fixed dosing). For this purpose, a comprehensive pharmacokinetic (PK) simulation study was performed. Methods: A virtual population of 1000 clinically representative CD patients was generated based on the distribution of CD patient characteristics from an in-house clinical database (n = 116). Seven dosing regimens were investigated: fixed dose and per BW, lean BW (LBW), body surface area, height, body mass index and fat-free mass. The individual body size-adjusted doses were calculated from patient generated body size descriptor values. Then, using published PK models for IFX and CZP in CD patients2,3, for each patient, 1000 concentration-time profiles were simulated to consider the typical profile of a specific patient as well as the range of possible individual profiles due to unexplained PK variability across patients. For each dosing strategy, the variability in maximum and minimum mAb concentrations (Cmax and Cmin, respectively), area under the concentration-time curve (AUC) and the per cent of patients reaching target concentration were assessed during maintenance therapy. Results: For IFX and CZP, Cmin showed the highest variability between patients (CV ≈110\% and CV ≈80\%, respectively) with a similar extent across all dosing strategies. For IFX, the per cent of patients reaching the target (Cmin = 5 µg/ml) was similar across all dosing strategies (~15\%). For CZP, the per cent of patients reaching the target average concentration of 17 µg/ml ranged substantially (52-71\%), being the highest for LBW-adjusted dosing. Conclusion: By using a PK simulation approach, different dosing regimen of IFX and CZP revealed the highest variability for Cmin, the most commonly used PK parameter guiding treatment decisions, independent upon dosing regimen. Our results demonstrate similar target attainment with fixed dosing of IFX compared with currently recommended BW-based dosing. For CZP, the current fixed dosing strategy leads to comparable percentage of patients reaching target as the best performing body size-adjusted dosing (66\% vs. 71\%, respectively).},
  language  = {en}
}
@inproceedings{OPUS4-60744,
  title     = {Entwicklungen, Chancen und Herausforderungen der Digitalisierung},
  volume    = {2},
  editor    = {Gronau, Norbert and Heine, Moreen and Poustcchi, Key and Krasnova, Hanna},
  publisher = {GITO mbH Verlag f{\"u}r Industrielle Informationstechnik und Organisation},
  address   = {Berlin},
  isbn      = {978-3-95545-336-7},
  doi       = {10.30844/wi_2020_ct},
  pages     = {309},
  year      = {2020},
  abstract  = {Stetig steigende Studierendenzahlen und Studierendenerwartungen der „Generation Z" als „Digital Natives" stellen Hochschulen bei gleichbleibenden Lehrressourcen vor vielf{\"a}ltige technische, didaktische, organisationale und curriculare Herausforderungen. Aufgrund ihrer Diversit{\"a}t und Heterogenit{\"a}t gibt es keinen einheitlichen Weg der digitalen Transformation im Hochschulsektor. Curricula, Studienstrukturen, Pr{\"a}senzlehre und digitale Lehr- und Lernangebote m{\"u}ssen auf die jeweiligen Hochschulen, Zielgruppen und Kooperationspartner zugeschnitten werden. Dabei m{\"u}ssen auch neue Zielgruppen erreicht werden, z.B. Berufst{\"a}tige und Teilzeitstudierende, und die Individualisierung sowie die nationale und internationale Studierendenmobilit{\"a}t gef{\"o}rdert werden. Kompetenzen f{\"u}r die Informationsextraktion aus Lern- und Studienprozessen, (Big) Data Analytics und Visualisierung, K{\"u}nstliche Intelligenz und Augmented Reality m{\"u}ssen in Hochschulen aufgebaut werden. Von der digitalen Transformation sind alle Bereiche von Hochschulen betroffen, z.B. Pr{\"a}sidien, Fakult{\"a}ten und gleichgestellte Einrichtungen, Universit{\"a}tsverwaltungen, Forschungseinrichtungen sowie zentrale und dezentrale (IT-)Dienstleister, die sich mit schnell ver{\"a}ndernden Anforderungs- und Rollenprofilen anpassen m{\"u}ssen. Ferner sind rechtliche Rahmenbedingungen zu betrachten, z.B. Datenschutzanforderungen, um die Potenziale von digitalen Lehr- und Lernangeboten und von digitalen Medien in der Lehre zu erschließen. Dieser Track diskutiert theoretische, konzeptionelle, gestaltungsorientierte, empirische und verhaltensorientierte Beitr{\"a}ge.},
  language  = {de}
}
@inproceedings{OPUS4-48311,
  title     = {Eine Methodenlehre oder viele Methoden?},
  editor    = {H{\"a}hnchen, Susanne},
  publisher = {Mohr Siebeck},
  address   = {T{\"u}bingen},
  isbn      = {978-3-16-159593-6},
  pages     = {VII, 134},
  year      = {2020},
  abstract  = {Die Methodenlehre ist das Grundlagenfach mit der gr{\"o}ßten N{\"a}he zur Praxis. Dennoch bewegt sie sich oftmals auf einer hohen Abstraktionsebene und ihr Zweck wird im juristischen Alltag, im Studium oder in der Praxis nicht immer erreicht. Dominiert vom Zivil- und insbesondere Arbeitsrecht, werden Besonderheiten des {\"O}ffentlichen Rechts und des Strafrechts ebenso wenig allgemein zur Kenntnis genommen wie (wieder) aktuelle Ans{\"a}tze etwa der Rechtsrhetorik, der {\"o}konomischen Analyse und der praktischen Jurisprudenz. Es sind eher interne Diskussionen, die innerhalb der Fachdisziplinen und in den noch kleineren Kreisen der methodisch Denkenden gef{\"u}hrt werden. Im Zentrum des Kolloquiums stand daher die Frage, ob es eine allgemeine Methodenlehre gibt oder jeweils spezifische Methoden. Ziel war es, {\"u}ber Generationen, F{\"a}chergrenzen und Schulen hinaus ins Gespr{\"a}ch zu kommen. Der Tagungsband vereint die Referate und kurzen Zusammenfassungen der anregenden Diskussionen.},
  language  = {de}
}