@article{FasciottiSanvidoSantosetal.2012, author = {Fasciotti, Maira and Sanvido, Gustavo B. and Santos, Vanessa G. and Lalli, Priscila M. and McCullagh, Michael and de Sa, Gilberto F. and Daroda, Romeu J. and Peter, Martin G. and Eberlin, Marcos N.}, title = {Separation of isomeric disaccharides by traveling wave ion mobility mass spectrometry using CO2 as drift gas}, series = {Journal of mass spectrometr}, volume = {47}, journal = {Journal of mass spectrometr}, number = {12}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {1076-5174}, doi = {10.1002/jms.3089}, pages = {1643 -- 1647}, year = {2012}, abstract = {The use of CO2 as a massive and polarizable drift gas is shown to greatly improve peak-to-peak resolution (Rp-p), as compared with N2, for the separation of disaccharides in a Synapt G2 traveling wave ion mobility cell. Near or baseline Rp-p was achieved for three pairs of sodiated molecules of disaccharide isomers, that is, cellobiose and sucrose (Rp-p?=?0.76), maltose and sucrose (Rp-p?=?1.04), and maltose and lactose (Rp-p?=?0.74). Ion mobility mass spectrometry using CO2 as the drift gas offers therefore an attractive alternative for fast and efficient separation of isomeric disaccharides.}, language = {en} }