@article{YenesewInduliDereseetal.2004,
  author    = {Yenesew, Abiy and Induli, M. and Derese, Solomon and Midiwo, Jacob O. and Heydenreich, Matthias and Peter, Martin G. and Akala, Hoseah M. and Wangui, Julia and Liyala, Pamela and Waters, Norman C.},
  title     = {Anti-plasmodial flavonoids from the stem bark of Erythrina abyssinica},
  issn      = {0031-9422},
  year      = {2004},
  abstract  = {The ethyl acetate extract of the stem bark of Erythrina abyssinica showed anti-plasmodial activity against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum with IC50 values of 7.9 +/- 1.1 and 5.3 +/- 0.7 mug/ml, respectively. From this extract, a new chalcone, 2,3,4,4'-tetrahydroxy-5- prenylchalcone (trivial name 5-prenylbutein) and a new flavanone, 4',7-dihydroxy-3'-methoxy-5'- prenylflavanone (trivial name, 5-deoxyabyssinin II) along with known flavonoids have been isolated as the anti- plasmodial principles. The structures were determined on the basis of spectroscopic evidence. (C) 2004 Elsevier Ltd. All rights reserved},
  language  = {en}
}
@article{AndayiYenesewDereseetal.2006,
  author    = {Andayi, Andrew W. and Yenesew, Abiy and Derese, Solomon and Midiwo, Jacob O. and Gitu, Peter M. and Jondiko, Ogoche J. I. and Akala, Hoseah M. and Liyala, Pamela and Wangui, Julia and Waters, Norman C. and Heydenreich, Matthias and Peter, Martin G.},
  title     = {Antiplasmodial flavonoids from Erythrina sacleuxii},
  issn      = {0032-0943},
  doi       = {10.1055/s-2005-873200},
  year      = {2006},
  abstract  = {The acetone extracts of the root bark and stem bark of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic separation of the acetone extract of the root bark afforded a new isoflavone, 7-hydroxy-4 -methoxy-3'- prenylisoflavone (trivial name 5-deoxy-3' - prenylbiochanin A) along with known isoflavonoids as the antiplasmodial principles. Flavonoids and isoflavonoids isolated from the stem bark of E. sucleuxii were also tested and showed antiplasmodial activities. The structures were determined on the basis of spectroscopic evidence},
  language  = {en}
}
@article{KeruboMidiwoDereseetal.2013,
  author    = {Kerubo, Leonidah Omosa and Midiwo, Jacob Ogweno and Derese, Solomon and Langat, Moses K. and Akala, Hoseah M. and Waters, Norman C. and Peter, Martin and Heydenreich, Matthias},
  title     = {Antiplasmodial activity of compounds from the surface exudates of senecio roseiflorus},
  series = {Natural product communications : an international journal for communications and reviews},
  volume    = {8},
  journal   = {Natural product communications : an international journal for communications and reviews},
  number    = {2},
  publisher = {NPC},
  address   = {Westerville},
  issn      = {1934-578X},
  pages     = {175 -- 176},
  year      = {2013},
  abstract  = {From the surface exudates of Senecio roseiflorus fourteen known methylated flavonoids and one phenol were isolated and characterized. The structures of these compounds were determined on the basis of their spectroscopic analysis. The surface exudate and the flavonoids isolated showed moderate to good antiplasmodial activity with 5,4'-dihydroxy-7-dimethoxyflavanone having the highest activity against chloroquine-sensitive (D6) and resistant (W2) strains of Plasmodium falciparum, with IC50 values of 3.2 +/- 0.8 and 4.4 +/- 0.01 mu g/mL respectively.},
  language  = {en}
}