@article{DiehlCernochZenkeetal.2010,
  author    = {Diehl, Christina and Cernoch, Peter and Zenke, Ingrid and Runge, Heike and Pitschke, Rona and Hartmann, Juergen and Tiersch, Brigitte and Schlaad, Helmut},
  title     = {Mechanistic study of the phase separation/crystallization process of poly(2-isopropyl-2-oxazoline) in hot water},
  issn      = {1744-683X},
  doi       = {10.1039/C0sm00114g},
  year      = {2010},
  abstract  = {The kinetics of the crystallization of thermoresponsive poly(2-isopropyl-2-oxazoline) in water and the time- dependent evolution of the morphology were examined using wide-angle X-ray scattering and conventional and cryogenic scanning electron microscopy. Results indicate that a temperature-induced phase separation produces a bicontinuous polymer network-like structure, which with the onset of crystallization collapses into individual particles (1-2 mu m in diameter) composed of a porous fiber mesh. Nanofibers then preferentially form at the particle surface, thus wrapping the microspheres like a ball of wool. The particle morphology is severely affected by changes in temperature and less by the initial polymer concentration.},
  language  = {en}
}
@article{SunCernochVoelkeletal.2016,
  author    = {Sun, Jing and Cernoch, Peter and V{\"o}lkel, Antje and Wei, Yuhan and Ruokolainen, Janne and Schlaad, Helmut},
  title     = {Aqueous Self-Assembly of a Protein-Mimetic Ampholytic Block Copolypeptide},
  series = {Macromolecules : a publication of the American Chemical Society},
  volume    = {49},
  journal   = {Macromolecules : a publication of the American Chemical Society},
  publisher = {American Chemical Society},
  address   = {Washington},
  issn      = {0024-9297},
  doi       = {10.1021/acs.macromol.6b00817},
  pages     = {5494 -- 5501},
  year      = {2016},
  abstract  = {This report describes the aggregation behavior of an ABC-type ampholytic block copolypeptide, poly(ethylene oxide)-block-poly(L-lysine)-block-poly(L-glutamate), in aqueous media in dependence of pH. Polypeptide secondary structures and self-assemblies are investigated by circular dichroism (CD), Fourier transform infrared (FT-IR) and NMR spectroscopy, zeta potential measurements, analytical ultracentrifugation (AUC), dynamic/static light scattering (DLS/SLS), and cryogenic transmission electron microscopy (cryoTEM). The polymer chains tend to form vesicles when the hydrophobic polypeptide helix is located at the chain end (acidic pH) and are existing as single chains when it is located in the center and flanked by the two hydrophilic segments (basic pH). Precipitation occurs in the intermediate pH range due to polyion complexation of the charged polypeptide segments.},
  language  = {en}
}