@misc{FeldmannLevermann2016,
  author    = {Feldmann, Johannes and Levermann, Anders},
  title     = {Similitude of ice dynamics against scaling of geometry and physical parameters},
  series = {Postprints der Universit{\"a}t Potsdam : Mathematisch Naturwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam : Mathematisch Naturwissenschaftliche Reihe},
  number    = {564},
  issn      = {1866-8372},
  doi       = {10.25932/publishup-41244},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-412441},
  pages     = {1753 -- 1769},
  year      = {2016},
  abstract  = {The concept of similitude is commonly employed in the fields of fluid dynamics and engineering but rarely used in cryospheric research. Here we apply this method to the problem of ice flow to examine the dynamic similitude of isothermal ice sheets in shallow-shelf approximation against the scaling of their geometry and physical parameters. Carrying out a dimensional analysis of the stress balance we obtain dimensionless numbers that characterize the flow. Requiring that these numbers remain the same under scaling we obtain conditions that relate the geometric scaling factors, the parameters for the ice softness, surface mass balance and basal friction as well as the ice-sheet intrinsic response time to each other. We demonstrate that these scaling laws are the same for both the (two-dimensional) flow-line case and the three-dimensional case. The theoretically predicted ice-sheet scaling behavior agrees with results from numerical simulations that we conduct in flow-line and three-dimensional conceptual setups. We further investigate analytically the implications of geometric scaling of ice sheets for their response time. With this study we provide a framework which, under several assumptions, allows for a fundamental comparison of the ice-dynamic behavior across different scales. It proves to be useful in the design of conceptual numerical model setups and could also be helpful for designing laboratory glacier experiments. The concept might also be applied to real-world systems, e.g., to examine the response times of glaciers, ice streams or ice sheets to climatic perturbations.},
  language  = {en}
}
@misc{OlejkoCywińskiBald2016,
  author    = {Olejko, Lydia and Cywiński, P. J. and Bald, Ilko},
  title     = {An ion-controlled four-color fluorescent telomeric switch on DNA origami structures},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-95831},
  pages     = {10339 -- 10347},
  year      = {2016},
  abstract  = {The folding of single-stranded telomeric DNA into guanine (G) quadruplexes is a conformational change that plays a major role in sensing and drug targeting. The telomeric DNA can be placed on DNA origami nanostructures to make the folding process extremely selective for K+ ions even in the presence of high Na+ concentrations. Here, we demonstrate that the K+-selective G-quadruplex formation is reversible when using a cryptand to remove K+ from the G-quadruplex. We present a full characterization of the reversible switching between single-stranded telomeric DNA and G-quadruplex structures using F{\"o}rster resonance energy transfer (FRET) between the dyes fluorescein (FAM) and cyanine3 (Cy3). When attached to the DNA origami platform, the G-quadruplex switch can be incorporated into more complex photonic networks, which is demonstrated for a three-color and a four-color FRET cascade from FAM over Cy3 and Cy5 to IRDye700 with G-quadruplex-Cy3 acting as a switchable transmitter.},
  language  = {en}
}
@article{OlejkoCywińskiBald2016,
  author    = {Olejko, Lydia and Cywiński, Piotr J. and Bald, Ilko},
  title     = {An ion-controlled four-color fluorescent telomeric switch on DNA origami structures},
  series = {Nanoscale},
  volume    = {8},
  journal   = {Nanoscale},
  publisher = {RSC Publ.},
  address   = {Cambridge},
  issn      = {2040-3372},
  doi       = {10.1039/C6NR00119J},
  pages     = {10339 -- 10347},
  year      = {2016},
  abstract  = {The folding of single-stranded telomeric DNA into guanine (G) quadruplexes is a conformational change that plays a major role in sensing and drug targeting. The telomeric DNA can be placed on DNA origami nanostructures to make the folding process extremely selective for K+ ions even in the presence of high Na+ concentrations. Here, we demonstrate that the K+-selective G-quadruplex formation is reversible when using a cryptand to remove K+ from the G-quadruplex. We present a full characterization of the reversible switching between single-stranded telomeric DNA and G-quadruplex structures using F{\"o}rster resonance energy transfer (FRET) between the dyes fluorescein (FAM) and cyanine3 (Cy3). When attached to the DNA origami platform, the G-quadruplex switch can be incorporated into more complex photonic networks, which is demonstrated for a three-color and a four-color FRET cascade from FAM over Cy3 and Cy5 to IRDye700 with G-quadruplex-Cy3 acting as a switchable transmitter.},
  language  = {en}
}