@article{LauxBierHoelzel2018,
  author    = {Laux, Eva-Maria and Bier, Frank Fabian and H{\"o}lzel, Ralph},
  title     = {Dielectrophoretic Stretching of DNA},
  series = {DNA Nanotechnology},
  journal   = {DNA Nanotechnology},
  edition   = {2},
  publisher = {Humana Press Inc.},
  address   = {New York},
  isbn      = {978-1-4939-8582-1},
  issn      = {1064-3745},
  doi       = {10.1007/978-1-4939-8582-1_14},
  pages     = {199 -- 208},
  year      = {2018},
  abstract  = {The spatial control of DNA and of self-assembled DNA constructs is a prerequisite for the preparation of DNA-based nanostructures and microstructures and a useful tool for studies on single DNA molecules. Here we describe a protocol for the accumulation of dissolved lambda-DNA molecules between planar microelectrodes by the action of inhomogeneous radiofrequency electric fields. The resulting AC electrokinetic forces stretch the DNA molecules and align them parallel to the electric field. The electrode preparation from off-the-shelf electronic components is explained, and a detailed description of the electronic setup is given. The experimental procedure is controlled in real-time by fluorescence microscopy.},
  language  = {en}
}
@article{LauxWengerBieretal.2020,
  author    = {Laux, Eva-Maria and Wenger, Christian and Bier, Frank Fabian and Hoelzel, Ralph},
  title     = {AC electrokinetic immobilization of organic dye molecules},
  series = {Analytical and bioanalytical chemistry : a merger of Fresenius' journal of analytical chemistry and Analusis},
  volume    = {412},
  journal   = {Analytical and bioanalytical chemistry : a merger of Fresenius' journal of analytical chemistry and Analusis},
  number    = {16},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1618-2642},
  doi       = {10.1007/s00216-020-02480-4},
  pages     = {3859 -- 3870},
  year      = {2020},
  abstract  = {The application of inhomogeneous AC electric fields for molecular immobilization is a very fast and simple method that does not require any adaptions to the molecule's functional groups or charges. Here, the method is applied to a completely new category of molecules: small organic fluorescence dyes, whose dimensions amount to only 1 nm or even less. The presented setup and the electric field parameters used allow immobilization of dye molecules on the whole electrode surface as opposed to pure dielectrophoretic applications, where molecules are attracted only to regions of high electric field gradients, i.e., to the electrode tips and edges. In addition to dielectrophoresis and AC electrokinetic flow, molecular scale interactions and electrophoresis at short time scales are discussed as further mechanisms leading to migration and immobilization of the molecules.},
  language  = {en}
}