@misc{FritzRosaSicard2018, author = {Fritz, Michael Andre and Rosa, Stefanie and Sicard, Adrien}, title = {Mechanisms Underlying the Environmentally Induced Plasticity of Leaf Morphology}, series = {Frontiers in genetics}, volume = {9}, journal = {Frontiers in genetics}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-8021}, doi = {10.3389/fgene.2018.00478}, pages = {25}, year = {2018}, abstract = {The primary function of leaves is to provide an interface between plants and their environment for gas exchange, light exposure and thermoregulation. Leaves have, therefore a central contribution to plant fitness by allowing an efficient absorption of sunlight energy through photosynthesis to ensure an optimal growth. Their final geometry will result from a balance between the need to maximize energy uptake while minimizing the damage caused by environmental stresses. This intimate relationship between leaf and its surroundings has led to an enormous diversification in leaf forms. Leaf shape varies between species, populations, individuals or even within identical genotypes when those are subjected to different environmental conditions. For instance, the extent of leaf margin dissection has, for long, been found to inversely correlate with the mean annual temperature, such that Paleobotanists have used models based on leaf shape to predict the paleoclimate from fossil flora. Leaf growth is not only dependent on temperature but is also regulated by many other environmental factors such as light quality and intensity or ambient humidity. This raises the question of how the different signals can be integrated at the molecular level and converted into clear developmental decisions. Several recent studies have started to shed the light on the molecular mechanisms that connect the environmental sensing with organ-growth and patterning. In this review, we discuss the current knowledge on the influence of different environmental signals on leaf size and shape, their integration as well as their importance for plant adaptation.}, language = {en} } @misc{LadwigZhouXuetal.2018, author = {Ladwig, Simon and Zhou, Zien and Xu, Ying and Wang, Xia and Chow, Clara K. and Werheid, Katja and Hackett, Maree L.}, title = {Comparison of treatment rates of depression after stroke versus myocardial infarction}, series = {Psychosomatic medicine}, volume = {80}, journal = {Psychosomatic medicine}, number = {8}, publisher = {Lippincott Williams \& Wilkins}, address = {Philadelphia}, issn = {0033-3174}, doi = {10.1097/PSY.0000000000000632}, pages = {754 -- 763}, year = {2018}, abstract = {Objective Depression after stroke and myocardial infarction (MI) is common but often assumed to be undertreated without reliable evidence being available. Thus, we aimed to determine treatment rates and investigate the application of guidelines in these conditions. Methods Databases MEDLINE, EMBASE, PsycInfo, Web of Science, CINAHL, and Scopus were systematically searched without language restriction from inception to June 30, 2017. Prospective observational studies with consecutive recruitment reporting any antidepressant treatment in adults with depression after stroke or MI were included. Random-effects models were used to calculate pooled estimates of treatment rates. Results Fifty-five studies reported 32 stroke cohorts (n = 8938; pooled frequency of depression = 34\%, 95\% confidence interval [CI] = 29\%-38\%) and 17 MI cohorts (n = 10,767; pooled frequency of depression = 24\%, 95\% CI = 20\%-28\%). In 29 stroke cohorts, 24\% (95\% CI = 20\%-27\%) of 2280 depressed people used antidepressant medication. In 15 MI cohorts, 14\% (95\% CI = 8\%-19\%) of 2381 depressed people used antidepressant medication indicating a lower treatment rate than in stroke. Two studies reported use of psychosocial interventions, indicating that less than 10\% of participants were treated. Conclusions Despite the high frequency of depression after stroke and MI and the existence of efficacious treatment strategies, people often remain untreated. Innovative strategies are needed to increase the use of effective antidepressive interventions in patients with cardiovascular disease.}, language = {en} } @misc{LewandowskyCowtanRisbeyetal.2018, author = {Lewandowsky, Stephan and Cowtan, Kevin and Risbey, James S. and Mann, Michael E. and Steinman, Byron A. and Oreskes, Naomi and Rahmstorf, Stefan}, title = {The 'pause' in global warming in historical context}, series = {Environmental research letters}, volume = {13}, journal = {Environmental research letters}, number = {12}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {1748-9326}, doi = {10.1088/1748-9326/aaf372}, pages = {25}, year = {2018}, abstract = {We review the evidence for a putative early 21st-century divergence between global mean surface temperature (GMST) and Coupled Model Intercomparison Project Phase 5 (CMIP5) projections. We provide a systematic comparison between temperatures and projections using historical versions of GMST products and historical versions of model projections that existed at the times when claims about a divergence were made. The comparisons are conducted with a variety of statistical techniques that correct for problems in previous work, including using continuous trends and a Monte Carlo approach to simulate internal variability. The results show that there is no robust statistical evidence for a divergence between models and observations. The impression of a divergence early in the 21st century was caused by various biases in model interpretation and in the observations, and was unsupported by robust statistics.}, language = {en} } @misc{ManzoniCapekPoradaetal.2018, author = {Manzoni, Stefano and Capek, Petr and Porada, Philipp and Thurner, Martin and Winterdahl, Mattias and Beer, Christian and Bruchert, Volker and Frouz, Jan and Herrmann, Anke M. and Lindahl, Bjorn D. and Lyon, Steve W. and Šantrůčkov{\´a}, Hana and Vico, Giulia and Way, Danielle}, title = {Reviews and syntheses}, series = {Biogeosciences}, volume = {15}, journal = {Biogeosciences}, number = {19}, publisher = {Copernicus}, address = {G{\"o}ttingen}, issn = {1726-4170}, doi = {10.5194/bg-15-5929-2018}, pages = {5929 -- 5949}, year = {2018}, abstract = {The cycling of carbon (C) between the Earth surface and the atmosphere is controlled by biological and abiotic processes that regulate C storage in biogeochemical compartments and release to the atmosphere. This partitioning is quantified using various forms of C-use efficiency (CUE) - the ratio of C remaining in a system to C entering that system. Biological CUE is the fraction of C taken up allocated to biosynthesis. In soils and sediments, C storage depends also on abiotic processes, so the term C-storage efficiency (CSE) can be used. Here we first review and reconcile CUE and CSE definitions proposed for autotrophic and heterotrophic organisms and communities, food webs, whole ecosystems and watersheds, and soils and sediments using a common mathematical framework. Second, we identify general CUE patterns; for example, the actual CUE increases with improving growth conditions, and apparent CUE decreases with increasing turnover. We then synthesize > 5000CUE estimates showing that CUE decreases with increasing biological and ecological organization - from uni-cellular to multicellular organisms and from individuals to ecosystems. We conclude that CUE is an emergent property of coupled biological-abiotic systems, and it should be regarded as a flexible and scale-dependent index of the capacity of a given system to effectively retain C.}, language = {en} } @misc{HeidbachRajabiCuietal.2018, author = {Heidbach, Oliver and Rajabi, Mojtaba and Cui, Xiaofeng and Fuchs, Karl and Mueller, Birgit and Reinecker, John and Reiter, Karsten and Tingay, Mark and Wenzel, Friedemann and Xie, Furen and Ziegler, Moritz O. and Zoback, Mary-Lou and Zoback, Mark}, title = {The World Stress Map database release 2016}, series = {Tectonophysics : international journal of geotectonics and the geology and physics of the interior of the earth}, volume = {744}, journal = {Tectonophysics : international journal of geotectonics and the geology and physics of the interior of the earth}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0040-1951}, doi = {10.1016/j.tecto.2018.07.007}, pages = {484 -- 498}, year = {2018}, abstract = {Knowledge of the present-day crustal in-situ stress field is a key for the understanding of geodynamic processes such as global plate tectonics and earthquakes. It is also essential for the management of geo-reservoirs and underground storage sites for energy and waste. Since 1986, the World Stress Map (WSM) project has systematically compiled the orientation of maximum horizontal stress (S-Hmax). For the 30th anniversary of the project, the WSM database has been updated significantly with 42,870 data records which is double the amount of data in comparison to the database release in 2008. The update focuses on areas with previously sparse data coverage to resolve the stress pattern on different spatial scales. In this paper, we present details of the new WSM database release 2016 and an analysis of global and regional stress pattern. With the higher data density, we can now resolve stress pattern heterogeneities from plate-wide to local scales. In particular, we show two examples of 40 degrees-60 degrees S-Hmax rotations within 70 km. These rotations can be used as proxies to better understand the relative importance of plate boundary forces that control the long wave-length pattern in comparison to regional and local controls of the crustal stress state. In the new WSM project phase IV that started in 2017, we will continue to further refine the information on the S-Hmax orientation and the stress regime. However, we will also focus on the compilation of stress magnitude data as this information is essential for the calibration of geomechanical-numerical models. This enables us to derive a 3-D continuous description of the stress tensor from point-wise and incomplete stress tensor information provided with the WSM database. Such forward models are required for safety aspects of anthropogenic activities in the underground and for a better understanding of tectonic processes such as the earthquake cycle.}, language = {en} } @misc{Schilling2018, author = {Schilling, Christopher L.}, title = {Under the Shadow of the Rising Sun}, series = {Shofar: An Interdisciplinary Journal of Jewish Studies}, volume = {36}, journal = {Shofar: An Interdisciplinary Journal of Jewish Studies}, number = {3}, publisher = {Purdue University Press}, address = {West Lafayette}, issn = {0882-8539}, doi = {10.1353/sho.2018.0044}, pages = {195 -- 204}, year = {2018}, language = {en} } @misc{RisbeyLewandowskyCowtanetal.2018, author = {Risbey, James S. and Lewandowsky, Stephan and Cowtan, Kevin and Oreskes, Naomi and Rahmstorf, Stefan and Jokim{\"a}ki, Ari and Foster, Grant}, title = {A fluctuation in surface temperature in historical context}, series = {Environmental research letters}, volume = {13}, journal = {Environmental research letters}, number = {12}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {1748-9326}, doi = {10.1088/1748-9326/aaf342}, pages = {23}, year = {2018}, abstract = {This work reviews the literature on an alleged global warming 'pause' in global mean surface temperature (GMST) to determine how it has been defined, what time intervals are used to characterise it, what data are used to measure it, and what methods used to assess it. We test for 'pauses', both in the normally understood meaning of the term to mean no warming trend, as well as for a 'pause' defined as a substantially slower trend in GMST. The tests are carried out with the historical versions of GMST that existed for each pause-interval tested, and with current versions of each of the GMST datasets. The tests are conducted following the common (but questionable) practice of breaking the linear fit at the start of the trend interval ('broken' trends), and also with trends that are continuous with the data bordering the trend interval. We also compare results when appropriate allowance is made for the selection bias problem. The results show that there is little or no statistical evidence for a lack of trend or slower trend in GMST using either the historical data or the current data. The perception that there was a 'pause' in GMST was bolstered by earlier biases in the data in combination with incomplete statistical testing.}, language = {en} } @misc{QuiterioMartinsOnofreetal.2018, author = {Quiterio, Ana and Martins, Joao and Onofre, Marcos and Costa, Joao and Rodrigues, Joao Mota and Gerlach, Erin and Scheur, Claude and Herrmann, Christian}, title = {MOBAK 1 assessment in primary physical education}, series = {Perceptual \& motor skills}, volume = {125}, journal = {Perceptual \& motor skills}, number = {6}, publisher = {Sage Publ.}, address = {Thousand Oaks}, issn = {0031-5125}, doi = {10.1177/0031512518804358}, pages = {1055 -- 1069}, year = {2018}, abstract = {Children's motor competence is known to have a determinant role in learning and engaging later in complex motor skills and, thus, in physical activity. The development of adequate motor competence is a central aim of physical education, and assuring that pupils are learning and developing motor competence depends on accurate assessment protocols. The MOBAK 1 test battery is a recent instrument developed to assess motor competence in primary physical education. This study used the MOBAK 1 to explore motor competence levels and gender differences among 249 (Mage = 6.3, SD = 0.5 years; 127 girls and 122 boys) Grade 1 primary school Portuguese children. On independent sample t tests, boys presented higher object movement motor competence than girls (boys: M = 5.8, SD = 1.7; girls: M = 4.0, SD = 1.7; p < .001), while girls were more proficient among self-movement skills (girls: M = 5.1, SD = 1.8; boys: M = 4.3, SD = 1.7; p < .01). On "total motor competence," boys (M = 10.3, SD = 2.6) averaged one point ahead of girls (M = 9.1, SD = 2.9). The percentage of girls in the first quartile of object movement was 18.9\%, while, for "self movement," the percentage of boys in the first quartile was almost double that of girls (30.3\% and 17.3\%, respectively). The confirmatory model to test for construct validity confirmed the assumed theoretical two-factor structure of MOBAK 1 test items in this Portuguese sample. These results support the MOBAK 1 instrument for assessing motor competence and highlighted gender differences, of relevance to intervention efforts.}, language = {en} } @misc{KrsticReinischSchuppetal.2018, author = {Krstic, Jelena and Reinisch, Isabel and Schupp, Michael and Schulz, Tim Julius and Prokesch, Andreas}, title = {p53 functions in adipose tissue metabolism and homeostasis}, series = {International journal of molecular sciences}, volume = {19}, journal = {International journal of molecular sciences}, number = {9}, publisher = {MDPI}, address = {Basel}, issn = {1422-0067}, doi = {10.3390/ijms19092622}, pages = {21}, year = {2018}, abstract = {As a tumor suppressor and the most frequently mutated gene in cancer, p53 is among the best-described molecules in medical research. As cancer is in most cases an age-related disease, it seems paradoxical that p53 is so strongly conserved from early multicellular organisms to humans. A function not directly related to tumor suppression, such as the regulation of metabolism in nontransformed cells, could explain this selective pressure. While this role of p53 in cellular metabolism is gradually emerging, it is imperative to dissect the tissue-and cell-specific actions of p53 and its downstream signaling pathways. In this review, we focus on studies reporting p53's impact on adipocyte development, function, and maintenance, as well as the causes and consequences of altered p53 levels in white and brown adipose tissue (AT) with respect to systemic energy homeostasis. While whole body p53 knockout mice gain less weight and fat mass under a high-fat diet owing to increased energy expenditure, modifying p53 expression specifically in adipocytes yields more refined insights: (1) p53 is a negative regulator of in vitro adipogenesis; (2) p53 levels in white AT are increased in diet-induced and genetic obesity mouse models and in obese humans; (3) functionally, elevated p53 in white AT increases senescence and chronic inflammation, aggravating systemic insulin resistance; (4) p53 is not required for normal development of brown AT; and (5) when p53 is activated in brown AT in mice fed a high-fat diet, it increases brown AT temperature and brown AT marker gene expression, thereby contributing to reduced fat mass accumulation. In addition, p53 is increasingly being recognized as crucial player in nutrient sensing pathways. Hence, despite existence of contradictory findings and a varying density of evidence, several functions of p53 in adipocytes and ATs have been emerging, positioning p53 as an essential regulatory hub in ATs. Future studies need to make use of more sophisticated in vivo model systems and should identify an AT-specific set of p53 target genes and downstream pathways upon different (nutrient) challenges to identify novel therapeutic targets to curb metabolic diseases}, language = {en} } @misc{Turner2018, author = {Turner, Bryan S.}, title = {Rezension zu: DeHanas, Daniel Nilsson: London Youth, Religion, and Politics: Engagement and Activism from Brixton to Brick Lane. - Oxford : Oxford University Press, 2016. - ISBN: 978-019874367-5}, series = {The British Journal of Sociology}, volume = {69}, journal = {The British Journal of Sociology}, number = {3}, publisher = {Wiley}, address = {Hoboken}, issn = {0007-1315}, doi = {10.1111/1468-4446.12361}, pages = {876 -- 877}, year = {2018}, language = {en} }