@article{KedrackiFilippovGouretal.2015, author = {Kedracki, Dawid and Filippov, Sergey K. and Gour, Nidhi and Schlaad, Helmut and Nardin, Corinne}, title = {Formation of DNA-Copolymer Fibrils Through an Amyloid-Like Nucleation Polymerization Mechanism}, series = {Macromolecular rapid communications}, volume = {36}, journal = {Macromolecular rapid communications}, number = {8}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1022-1336}, doi = {10.1002/marc.201400728}, pages = {768 -- 773}, year = {2015}, abstract = {Conjugation of a hydrophobic poly(2-oxazoline) bearing tertiary amide groups along its backbone with a short single stranded nucleotide sequence results in an amphiphilic comb/graft copolymer, which organizes in fibrils upon direct dissolution in water. Supported by circular dichroism, atomic force microscopy, transmission electron microscopy, and scattering data, fibrils are formed through inter- and intramolecular hydrogen bonding between hydrogen accepting amide groups along the polymer backbone and hydrogen donating nucleic acid grafts leading to the formation of hollow tubes.}, language = {en} }