@article{FriedrichOberkoflerTrindadeetal.2021, author = {Friedrich, Thomas and Oberkofler, Vicky and Trindade, In{\^e}s and Altmann, Simone and Brzezinka, Krzysztof and L{\"a}mke, J{\"o}rn S. and Gorka, Michal and Kappel, Christian and Sokolowska, Ewelina and Skirycz, Aleksandra and Graf, Alexander and B{\"a}urle, Isabel}, title = {Heteromeric HSFA2/HSFA3 complexes drive transcriptional memory after heat stress in Arabidopsis}, series = {Nature Communications}, volume = {12}, journal = {Nature Communications}, number = {1}, publisher = {Nature Publishing Group UK}, address = {[London]}, issn = {2041-1723}, doi = {10.1038/s41467-021-23786-6}, pages = {15}, year = {2021}, abstract = {Adaptive plasticity in stress responses is a key element of plant survival strategies. For instance, moderate heat stress (HS) primes a plant to acquire thermotolerance, which allows subsequent survival of more severe HS conditions. Acquired thermotolerance is actively maintained over several days (HS memory) and involves the sustained induction of memory-related genes. Here we show that FORGETTER3/ HEAT SHOCK TRANSCRIPTION FACTOR A3 (FGT3/HSFA3) is specifically required for physiological HS memory and maintaining high memory-gene expression during the days following a HS exposure. HSFA3 mediates HS memory by direct transcriptional activation of memory-related genes after return to normal growth temperatures. HSFA3 binds HSFA2, and in vivo both proteins form heteromeric complexes with additional HSFs. Our results indicate that only complexes containing both HSFA2 and HSFA3 efficiently promote transcriptional memory by positively influencing histone H3 lysine 4 (H3K4) hyper-methylation. In summary, our work defines the major HSF complex controlling transcriptional memory and elucidates the in vivo dynamics of HSF complexes during somatic stress memory. Moderate heat stress primes plants to acquire tolerance to subsequent, more severe heat stress. Here the authors show that the HSFA3 transcription factor forms a heteromeric complex with HSFA2 to sustain activated transcription of genes required for acquired thermotolerance by promoting H3K4 hyper-methylation.}, language = {en} } @article{BlaesiusFriedrichLischeidetal.2022, author = {Bl{\"a}sius, Thomas and Friedrich, Tobias and Lischeid, Julius and Meeks, Kitty and Schirneck, Friedrich Martin}, title = {Efficiently enumerating hitting sets of hypergraphs arising in data profiling}, series = {Journal of computer and system sciences : JCSS}, volume = {124}, journal = {Journal of computer and system sciences : JCSS}, publisher = {Elsevier}, address = {San Diego}, issn = {0022-0000}, doi = {10.1016/j.jcss.2021.10.002}, pages = {192 -- 213}, year = {2022}, abstract = {The transversal hypergraph problem asks to enumerate the minimal hitting sets of a hypergraph. If the solutions have bounded size, Eiter and Gottlob [SICOMP'95] gave an algorithm running in output-polynomial time, but whose space requirement also scales with the output. We improve this to polynomial delay and space. Central to our approach is the extension problem, deciding for a set X of vertices whether it is contained in any minimal hitting set. We show that this is one of the first natural problems to be W[3]-complete. We give an algorithm for the extension problem running in time O(m(vertical bar X vertical bar+1) n) and prove a SETH-lower bound showing that this is close to optimal. We apply our enumeration method to the discovery problem of minimal unique column combinations from data profiling. Our empirical evaluation suggests that the algorithm outperforms its worst-case guarantees on hypergraphs stemming from real-world databases.}, language = {en} } @article{RibackiTrumbullLopezDeLuchietal.2022, author = {Ribacki, Enrico and Trumbull, Robert B. and Lopez De Luchi, Monica Graciela and Altenberger, Uwe}, title = {The chemical and B-Isotope composition of Tourmaline from intra-granitic Pegmatites in the Las Chacras-Potrerillos Batholith, Argentina}, series = {The Canadian mineralogist : journal of the Mineralogical Association of Canada}, volume = {60}, journal = {The Canadian mineralogist : journal of the Mineralogical Association of Canada}, number = {1}, publisher = {Association of Canada}, address = {Ottawa}, issn = {0008-4476}, doi = {10.3749/canmin.2100036}, pages = {49 -- 66}, year = {2022}, abstract = {The Devonian Las Chacras-Potrerillos batholith comprises six nested monzonitic to granitic intrusions with metaluminous to weakly peraluminous composition and a Sr-Nd isotopic signature indicating a dominantly juvenile mantle-derived source. The chemically most evolved units in the southern batholith contain a large number of intra-granitic, pod-shaped tourmaline-bearing pegmatites. This study uses in situ chemical and boron isotopic analyses of tourmaline from nine of these pegmatites to discuss their relationship to the respective host intrusions and the implications of their B-isotope composition for the source and evolution of the magmas. The tourmalines reveal a diversity in element composition (e.g., FeO, MgO, TiO2, CaO, MnO, F) which distinguishes individual pegmatites from one another. However, all have a narrow 5 11 B range of -13.7 to -10.5\%0 (n = 100) which indicates a relatively uniform magmatic system and similar temperature conditions during tourmaline crystallization. The average delta(11) B value of -11.7\%0 is typical for S-type granites and is within the range reported for peraluminous granites. pegmatites, and metamorphic units of the Ordovician basement into which the Las Chacras-Potrerillos batholith intruded. The B-isotope evidence argues for a crustal boron source like that of the Ordovician basement, in contrast to the metaluminous to weakly peraluminous composition and juvenile initial Sr and Nd isotope ratios of the Las Chacras-Potrerillos batholith magmas. We propose that the boron was not derived from the magma source region but was incorporated from dehydration melting of elastic metasedimentary rocks higher up in the crustal column.}, language = {en} } @article{SantamansCordobaFrancoetal.2021, author = {Santamans, Carla Daniela and Cordoba, Francisco E. and Franco, Mar{\´i}a G. and Vignoni, Paula and Lupo, Liliana C.}, title = {Hydro-climatological variability in Lagunas de Vilama System, Argentinean Altiplano-Puna Plateau, Southern Tropical Andes (22 degrees S) and its response to large-scale climate forcings}, series = {The science of the total environment : an international journal for scientific research into the environment and its relationship with man}, volume = {767}, journal = {The science of the total environment : an international journal for scientific research into the environment and its relationship with man}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0048-9697}, doi = {10.1016/j.scitotenv.2020.144926}, pages = {19}, year = {2021}, abstract = {The Altiplano-Puna Plateau holds several shallow lakes, which are very sensitive to climate changes. This work is focused on a high-altitude lake system called Lagunas de Vilama (LVS), located in a complex climatic transition area with scarcity of continuous and homogeneous instrumental records. The objective of this study is to determine the regional spatial-temporal variability of precipitation and evaluate the seasonal and interannual lake responses. We use a lake-surfaces record derived from Landsat images to investigate links with regional precipitations and different climatic forcings. The results reveal that austral summer and autumn precipitations control the variability of the annual lake-surfaces. Also, we found intra-annual and interannual lags in the lake responses to precipitations, and identified several wet and dry stages. Our results show negative trends in precipitations and lake-surfaces, whose were strengthened by a shift to a warm phase of the Atlantic Multidecadal Oscillation in the 1990s. The El Nino Southern Oscillation, Pacific Decadal Oscillation, and Southern Annular Mode also exert a strong influence in the region. This study demonstrates that the variability of LVS lakes is strongly related to the South American Monsoon System dynamics and large-scale climate fordngs from the Pacific and Atlantic Oceans. This work provides novel indices which demonstrated to be good indicators of regional hydroclimatological variability for this region of South America.}, language = {en} } @article{EshghiMachReichel2021, author = {Eshghi, Nasim and Mach, Thomas and Reichel, Lothar}, title = {New matrix function approximations and quadrature rules based on the Arnoldi process}, series = {Journal of computational and applied mathematics}, volume = {391}, journal = {Journal of computational and applied mathematics}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0377-0427}, doi = {10.1016/j.cam.2021.113442}, pages = {12}, year = {2021}, abstract = {The Arnoldi process can be applied to inexpensively approximate matrix functions of the form f (A)v and matrix functionals of the form v*(f (A))*g(A)v, where A is a large square non-Hermitian matrix, v is a vector, and the superscript * denotes transposition and complex conjugation. Here f and g are analytic functions that are defined in suitable regions in the complex plane. This paper reviews available approximation methods and describes new ones that provide higher accuracy for essentially the same computational effort by exploiting available, but generally not used, moment information. Numerical experiments show that in some cases the modifications of the Arnoldi decompositions proposed can improve the accuracy of v*(f (A))*g(A)v about as much as performing an additional step of the Arnoldi process.}, language = {en} } @article{CarpioAriasAriasMogrovejoNicolaldeCifuentesetal.2021, author = {Carpio Arias, Tannia Valeria and Arias Mogrovejo, Diana Carolina and Nicolalde Cifuentes, Tom{\´a}s Marcelo and Tapia Veloz, Estephany Carolina and Zeeuw, Chris I. de and Vinueza Veloz, Maria Fernanda}, title = {Sleep quality does not mediate the negative effects of chronodisruption on body composition and metabolic syndrome in healthcare workers in Ecuador}, series = {Diabetes \& metabolic syndrome : clinical research \& reviews ; the official journal of DiabetesIndia}, volume = {15}, journal = {Diabetes \& metabolic syndrome : clinical research \& reviews ; the official journal of DiabetesIndia}, number = {1}, publisher = {Elsevier}, address = {Amsterdam [u.a.]}, issn = {1871-4021}, doi = {10.1016/j.dsx.2021.01.017}, pages = {397 -- 402}, year = {2021}, abstract = {Background and aims: The objective of the present work was to determine to what extent sleep quality may mediate the association between chronodisruption (CD) and metabolic syndrome (MS), and between CD and body composition (BC). Methodology: Cross-sectional study which included 300 adult health workers, 150 of whom were night shift workers and thereby exposed to CD. Diagnosis of MS was made based on Adult Treatment Panel III criteria. Sleep quality was measured using the Pittsburgh Sleep Quality Index. Body mass index (BMI), fat mass percentage, and visceral fat percentage were measured as indicators of body composition (BC). Data were analyzed using logistic, linear regression and structural equation models. Results: The odds of health workers exposed to CD to suffer MS was 22.13 (IC95 8.68-66.07) when the model was adjusted for age, gender, physical activity and energy consumption. CD was also significantly associated with an increase in fat mass and visceral fat percentages, but not to BMI. Surprisingly, there was not enough evidence supporting the hypothesis that sleep quality contributes to the association between CD and MS or between CD and BC. Conclusions: Sleep quality does not mediate the negative effects of CD on MS nor on BC.}, language = {en} } @article{KloseWunderlingWinkelmannetal.2021, author = {Klose, Ann Kristin and Wunderling, Nico and Winkelmann, Ricarda and Donges, Jonathan}, title = {What do we mean, 'tipping cascade'?}, series = {Environmental research letters : ERL}, volume = {16}, journal = {Environmental research letters : ERL}, number = {12}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {1748-9326}, doi = {10.1088/1748-9326/ac3955}, pages = {11}, year = {2021}, abstract = {Based on suggested interactions of potential tipping elements in the Earth's climate and in ecological systems, tipping cascades as possible dynamics are increasingly discussed and studied. The activation of such tipping cascades would impose a considerable risk for human societies and biosphere integrity. However, there are ambiguities in the description of tipping cascades within the literature so far. Here we illustrate how different patterns of multiple tipping dynamics emerge from a very simple coupling of two previously studied idealized tipping elements. In particular, we distinguish between a two phase cascade, a domino cascade and a joint cascade. A mitigation of an unfolding two phase cascade may be possible and common early warning indicators are sensitive to upcoming critical transitions to a certain degree. In contrast, a domino cascade may hardly be stopped once initiated and critical slowing down-based indicators fail to indicate tipping of the following element. These different potentials for intervention and anticipation across the distinct patterns of multiple tipping dynamics should be seen as a call to be more precise in future analyses of cascading dynamics arising from tipping element interactions in the Earth system.}, language = {en} } @article{SperlichKoeckerling2023, author = {Sperlich, Eric and K{\"o}ckerling, Martin}, title = {The double cluster compound [Nb6Cl14(MeCN)(4)] [Nb6Cl14(pyz)(4)].6MeCN (Me: methyl, pyz: pyrazine) with a layered structure resulting from weak intermolecular interactions}, series = {Zeitschrift f{\"u}r Naturforschung}, volume = {78}, journal = {Zeitschrift f{\"u}r Naturforschung}, number = {5}, publisher = {De Gruyter}, address = {Berlin}, issn = {0932-0776}, doi = {10.1515/znb-2023-0001}, pages = {279 -- 283}, year = {2023}, abstract = {The synthesis and the crystal structure of the double cluster compound [Nb6Cl14(MeCN)(4)][Nb6Cl14(pyz)(4)]middot6CH(3)CN are described. The synthesis is based on a partial ligand exchange reaction, which proceeds upon dissolving [Nb6Cl14(pyz)(4)]middot2CH(2)Cl(2) in acetonitrile. The compound is built up of two discrete neutral cluster units, which consist of octahedra of Nb-6 atoms coordinated by 12 edge-bridging chlorido and two terminal chlorido ligands, and four acetonitrile ligands on one and four pyrazine ligands on the other cluster unit. Co-crystallized acetonitrile molecules are also present. The single-crystal structure determination has revealed a cluster arrangement in which the [Nb6Cl14(pyz)(4)] units are connected by (halogen) lone-pair-(pyrazine) pi interactions. These lead to chains of [Nb6Cl14(pyz)(4)] clusters. These chains are further connected to cluster layers by (nitrile-halogen) dipole-dipole interactions, in which the [Nb6Cl14(MeCN)(4)] and co-crystallized MeCN molecules are also involved. These cluster layers are arranged parallel to the crystallographic {011} plane.}, language = {en} } @article{SellemAntoniKoutsosetal.2022, author = {Sellem, Laury and Antoni, Rona and Koutsos, Athanasios and Ozen, Ezgi and Wong, Gloria and Ayyad, Hasnaa and Weech, Michelle and Schulze, Matthias Bernd and Wernitz, Andreas and Fielding, Barbara A. and Robertson, M. Denise and Jackson, Kim G. and Griffin, Bruce A. and Lovegrove, Julie A.}, title = {Impact of a food-based dietary fat exchange model for replacing dietary saturated with unsaturated fatty acids in healthy men on plasma phospholipids fatty acid profiles and dietary patterns}, series = {European journal of nutrition}, volume = {61}, journal = {European journal of nutrition}, number = {7}, publisher = {Springer}, address = {Heidelberg}, issn = {1436-6207}, doi = {10.1007/s00394-022-02910-2}, pages = {3669 -- 3684}, year = {2022}, abstract = {Purpose UK guidelines recommend dietary saturated fatty acids (SFAs) should not exceed 10\% total energy (\%TE) for cardiovascular disease prevention, with benefits observed when SFAs are replaced with unsaturated fatty acids (UFAs). This study aimed to assess the efficacy of a dietary exchange model using commercially available foods to replace SFAs with UFAs. Methods Healthy men (n = 109, age 48, SD 11 year) recruited to the Reading, Imperial, Surrey, Saturated fat Cholesterol Intervention-1 (RISSCI-1) study (ClinicalTrials.Gov n degrees NCT03270527) followed two sequential 4-week isoenergetic moderate-fat (34\%TE) diets: high-SFA (18\%TE SFAs, 16\%TE UFAs) and low-SFA (10\%TE SFAs, 24\%TE UFAs). Dietary intakes were assessed using 4-day weighed diet diaries. Nutrient intakes were analysed using paired t-tests, fasting plasma phospholipid fatty acid (PL-FA) profiles and dietary patterns were analysed using orthogonal partial least square discriminant analyses. Results Participants exchanged 10.2\%TE (SD 4.1) SFAs for 9.7\%TE (SD 3.9) UFAs between the high and low-SFA diets, reaching target intakes with minimal effect on other nutrients or energy intakes. Analyses of dietary patterns confirmed successful incorporation of recommended foods from commercially available sources (e.g. dairy products, snacks, oils, and fats), without affecting participants' overall dietary intakes. Analyses of plasma PL-FAs indicated good compliance to the dietary intervention and foods of varying SFA content. Conclusions RISSCI-1 dietary exchange model successfully replaced dietary SFAs with UFAs in free-living healthy men using commercially available foods, and without altering their dietary patterns. Further intervention studies are required to confirm utility and feasibility of such food-based dietary fat replacement models at a population level.}, language = {en} } @article{MaitiMakwanaZhangetal.2022, author = {Maiti, Snehanshu and Makwana, Kirit and Zhang, Heshou and Yan, Huirong}, title = {Cosmic-ray transport in magnetohydrodynamic turbulence}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics / part 1}, volume = {926}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics / part 1}, number = {1}, publisher = {Institute of Physics Publ.}, address = {London}, issn = {1538-4357}, doi = {10.3847/1538-4357/ac46c8}, pages = {8}, year = {2022}, abstract = {This paper studies cosmic-ray (CR) transport in magnetohydrodynamic (MHD) turbulence. CR transport is strongly dependent on the properties of the magnetic turbulence. We perform test particle simulations to study the interactions of CR with both total MHD turbulence and decomposed MHD modes. The spatial diffusion coefficients and the pitch angle scattering diffusion coefficients are calculated from the test particle trajectories in turbulence. Our results confirm that the fast modes dominate the CR propagation, whereas Alfven and slow modes are much less efficient and have shown similar pitch-angle scattering rates. We investigate the cross field transport on large and small scales. On large/global scales, normal diffusion is observed and the diffusion coefficient is suppressed by M-A(zeta) compared to the parallel diffusion coefficients, with zeta closer to 4 in Alfven modes than that in total turbulence, as theoretically expected. For the CR transport on scales smaller than the turbulence injection scale, both the local and global magnetic reference frames are adopted. Superdiffusion is observed on such small scales in all the cases. Particularly, CR transport in Alfven modes show clear Richardson diffusion in the local reference frame. The diffusion transitions smoothly from the Richardson's one with index 1.5 to normal diffusion as the particle mean free path decreases from lambda(parallel to) >> L to lambda(parallel to) << L, where L is the injection/coherence length of turbulence. Our results have broad applications to CRs in various astrophysical environments.}, language = {en} }