@article{HoefsHuelagueBennetetal.2021, author = {H{\"o}fs, Soraya and Huelague, Deniz and Bennet, Francesca and Carl, Peter and Flemig, Sabine and Schmid, Thomas and Schenk, Jorg A. and Hodoroaba, Vasile-Dan and Schneider, Rudolf J.}, title = {Electrochemical immunomagnetic Ochratoxin A sensing}, series = {ChemElectroChem}, volume = {8}, journal = {ChemElectroChem}, number = {13}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {2196-0216}, doi = {10.1002/celc.202100446}, pages = {2597 -- 2606}, year = {2021}, abstract = {Electrochemical methods offer great promise in meeting the demand for user-friendly on-site devices for monitoring important parameters. The food industry often runs own lab procedures, for example, for mycotoxin analysis, but it is a major goal to simplify analysis, linking analytical methods with smart technologies. Enzyme-linked immunosorbent assays, with photometric detection of 3,3',5,5'-tetramethylbenzidine (TMB), form a good basis for sensitive detection. To provide a straightforward approach for the miniaturization of the detection step, we have studied the pitfalls of the electrochemical TMB detection. By cyclic voltammetry it was found that the TMB electrochemistry is strongly dependent on the pH and the electrode material. A stable electrode response to TMB could be achieved at pH 1 on gold electrodes. We created a smartphone-based, electrochemical, immunomagnetic assay for the detection of ochratoxin A in real samples, providing a solid basis for sensing of further analytes.}, language = {en} } @article{PanLiuGouetal.2021, author = {Pan, Hanya and Liu, Rui and Gou, Tingyu and Kliem, Bernhard and Su, Yingna and Chen, Jun and Wang, Yuming}, title = {Pre-eruption splitting of the double-decker structure in a solar filament}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, volume = {909}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, number = {1}, publisher = {Institute of Physics Publ.}, address = {London}, issn = {0004-637X}, doi = {10.3847/1538-4357/abda4e}, pages = {12}, year = {2021}, abstract = {Solar filaments often erupt partially. Although how they split remains elusive, the splitting process has the potential of revealing the filament structure and eruption mechanism. Here we investigate the pre-eruption splitting of an apparently single filament and its subsequent partial eruption on 2012 September 27. The evolution is characterized by three stages with distinct dynamics. During the quasi-static stage, the splitting proceeds gradually for about 1.5 hr, with the upper branch rising at a few kilometers per second and displaying swirling motions about its axis. During the precursor stage that lasts for about 10 minutes, the upper branch rises at tens of kilometers per second, with a pair of conjugated dimming regions starting to develop at its footpoints; with the swirling motions turning chaotic, the axis of the upper branch whips southward, which drives an arc-shaped extreme-ultraviolet front propagating in a similar direction. During the eruption stage, the upper branch erupts with the onset of a C3.7-class two-ribbon flare, while the lower branch remains stable. Judging from the well-separated footpoints of the upper branch from those of the lower one, we suggest that the pre-eruption filament processes a double-decker structure composed of two distinct flux bundles, whose formation is associated with gradual magnetic flux cancellations and converging photospheric flows around the polarity inversion line.}, language = {en} } @article{Homolka2021, author = {Homolka, Walter}, title = {Glaubensfragen}, series = {{\"U}ber Grenzen hinweg zu neuer Gemeinschaft - Bilanz und Perspektiven des christlich-j{\"u}dischen Gespr{\"a}chs (Reihe: Forum Christen und Juden/Forum for Christians and Jews)}, volume = {23}, journal = {{\"U}ber Grenzen hinweg zu neuer Gemeinschaft - Bilanz und Perspektiven des christlich-j{\"u}dischen Gespr{\"a}chs (Reihe: Forum Christen und Juden/Forum for Christians and Jews)}, publisher = {LIT}, address = {Berlin, M{\"u}nster}, isbn = {978-3-643-15083-7}, pages = {374}, year = {2021}, abstract = {Der Artikel gibt einen {\"U}berblick {\"u}ber die verschiedenen Phasen von siebzig Jahren christlich-j{\"u}discher Dialog und blickt in die Zukunft. Akzeptieren Christen die Konsequenzen, die aus der Immanenz des Judentums in ihrer Religion folgen? Vor allem in zentralen Handlungsfeldern der systematischen Theologie bleibt viel Raum f{\"u}r Entwicklung, allen voran der Christologie.}, language = {de} } @article{TellaWinterleitnerMorsillietal.2022, author = {Tella, Timothy O. and Winterleitner, Gerd and Morsilli, Michele and Mutti, Maria}, title = {Testing sea-level and carbonate production effects on stratal architecture of a distally steepened carbonate ramp (Upper Miocene, Menorca)}, series = {Sedimentary geology : international journal of applied and regional sedimentology}, volume = {441}, journal = {Sedimentary geology : international journal of applied and regional sedimentology}, publisher = {Elsevier}, address = {Amsterdam [u.a.]}, issn = {0037-0738}, doi = {10.1016/j.sedgeo.2022.106267}, pages = {18}, year = {2022}, abstract = {Although distally steepened carbonate ramps have been studied by numerous researchers, the processes that control the development of these carbonate systems, including tectonics, differential carbonate production along the ramp profile, or antecedent physiography of the slopes, are an ongoing discussion. We use a stratigraphic forward model to test different hypotheses to unravel controls over distally steepened ramp development, referenced to the well-known Upper Miocene Menorca carbonate ramp (Spain). Sensitivity tests show that distally steepened ramps develop under complex interaction among accommodation, carbonate production and sediment transport parameters. Ramp slope initiation is favoured by still stands and falls of sea-level, in a setting with high-frequency sea-level fluctuations with amplitude between 20 m and 40 m. Low-frequency and higher amplitude sea-level fluctuations of about 115 m tend to form models with no significant slope development. The impact of antecedent slope on the geometry of ramps is determined by the paleoslope inclination, with flat to subhorizontal paleosurfaces resulting in ramps that mirror the antecedent slope. In contrast, steeper paleosurfaces tend to result in ramps with well-defined slopes. Our models, therefore, show that the ramp profile becomes more influenced by the depth constraints on the carbonate sediment producers than by the geometry of the underlying topography as the inclination of the paleosurface increases. The presented models also show that seagrass-dominated shallow carbonate production tends to result in steep slopes due to the low-transport characteristic imposed by seagrass trapping. This steepness can, however, be altered by the introduction of high transport sediment grains from deeper carbonate producers, which fill the slopes and more distal sections of the ramp profile.}, language = {en} } @article{BehmAlizadehHadjizedahAnvaretal.2021, author = {Behm, David G. and Alizadeh, Shahab and Hadjizedah Anvar, Saman and Hanlon, Courtney and Ramsay, Emma and Mahmoud, Mohamed Mamdouh Ibrahim and Whitten, Joseph and Fisher, James P. and Prieske, Olaf and Chaabene, Helmi and Granacher, Urs and Steele, James}, title = {Non-local muscle fatigue effects on muscle strength, power, and endurance in healthy individuals}, series = {Sports medicine : the world's premier sports medicine preview journal}, volume = {51}, journal = {Sports medicine : the world's premier sports medicine preview journal}, number = {9}, publisher = {Springer}, address = {Berlin [u.a.]}, issn = {0112-1642}, doi = {10.1007/s40279-021-01456-3}, pages = {1893 -- 1907}, year = {2021}, abstract = {Background The fatigue of a muscle or muscle group can produce global responses to a variety of systems (i.e., cardiovascular, endocrine, and others). There are also reported strength and endurance impairments of non-exercised muscles following the fatigue of another muscle; however, the literature is inconsistent. Objective To examine whether non-local muscle fatigue (NLMF) occurs following the performance of a fatiguing bout of exercise of a different muscle(s). Design Systematic review and meta-analysis. Search and Inclusion A systematic literature search using a Boolean search strategy was conducted with PubMed, SPORTDiscus, Web of Science, and Google Scholar in April 2020, and was supplemented with additional 'snowballing' searches up to September 2020. To be included in our analysis, studies had to include at least one intentional performance measure (i.e., strength, endurance, or power), which if reduced could be considered evidence of muscle fatigue, and also had to include the implementation of a fatiguing protocol to a location (i.e., limb or limbs) that differed to those for which performance was measured. We excluded studies that measured only mechanistic variables such as electromyographic activity, or spinal/supraspinal excitability. After search and screening, 52 studies were eligible for inclusion including 57 groups of participants (median sample = 11) and a total of 303 participants. Results The main multilevel meta-analysis model including all effects sizes (278 across 50 clusters [median = 4, range = 1 to 18 effects per cluster) revealed a trivial point estimate with high precision for the interval estimate [- 0.02 (95\% CIs = - 0.14 to 0.09)], yet with substantial heterogeneity (Q((277)) = 642.3, p < 0.01), I-2 = 67.4\%). Subgroup and meta-regression analyses showed that NLMF effects were not moderated by study design (between vs. within-participant), homologous vs. heterologous effects, upper or lower body effects, participant training status, sex, age, the time of post-fatigue protocol measurement, or the severity of the fatigue protocol. However, there did appear to be an effect of type of outcome measure where both strength [0.11 (95\% CIs = 0.01-0.21)] and power outcomes had trivial effects [- 0.01 (95\% CIs = - 0.24 to 0.22)], whereas endurance outcomes showed moderate albeit imprecise effects [- 0.54 (95\% CIs = - 0.95 to - 0.14)]. Conclusions Overall, the findings do not support the existence of a general NLMF effect; however, when examining specific types of performance outcomes, there may be an effect specifically upon endurance-based outcomes (i.e., time to task failure). However, there are relatively fewer studies that have examined endurance effects or mechanisms explaining this possible effect, in addition to fewer studies including women or younger and older participants, and considering causal effects of prior training history through the use of longitudinal intervention study designs. Thus, it seems pertinent that future research on NLMF effects should be redirected towards these still relatively unexplored areas.}, language = {en} } @article{RonkainenPesolaTikkanenetal.2021, author = {Ronkainen, Noora J. and Pesola, Arto J. and Tikkanen, Olli and Brand, Ralf}, title = {Continuity and discontinuity of sport and exercise type during the COVID-19 pandemic}, series = {Frontiers in psychology}, volume = {12}, journal = {Frontiers in psychology}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-1078}, doi = {10.3389/fpsyg.2021.622876}, pages = {10}, year = {2021}, abstract = {Involvement in sport and exercise not only provides participants with health benefits but can be an important aspect of living a meaningful life. The COVID-19 pandemic and the temporary cessation of public life in March/April/May 2020 came with restrictions, which probably also made it difficult, if not impossible, to participate in certain types of sport or exercise. Following the philosophical position that different types of sport and exercise offer different ways of "relating to the world," this study explored (dis)continuity in the type of sport and exercise people practiced during the pandemic-related lockdown, and possible effects on mood. Data from a survey of 601 adult exercisers, collected shortly after the COVID-19 outbreak in Finland, were analyzed. Approximately one third (35\%) of the participants changed their "worldmaking" and shifted to "I-Nature"-type activities. We observed worse mood during the pandemic in those who shifted from "I-Me," compared to those who had preferred the "I-Nature" relation already before the pandemic and thus experienced continuity. The clouded mood of those experiencing discontinuity may be the result of a temporary loss of "feeling at home" in their new exercise life-world. However, further empirical investigation must follow, because the observed effect sizes were small.}, language = {en} } @article{RazaghiMoghadamSokolowskaSowaetal.2021, author = {Razaghi-Moghadam, Zahra and Sokolowska, Ewelina and Sowa, Marcin A. and Skirycz, Aleksandra and Nikoloski, Zoran}, title = {Combination of network and molecule structure accurately predicts competitive inhibitory interactions}, series = {Computational and structural biotechnology journal}, volume = {19}, journal = {Computational and structural biotechnology journal}, publisher = {Research Network of Computational and Structural Biotechnology (RNCSB)}, address = {Gotenburg}, issn = {2001-0370}, doi = {10.1016/j.csbj.2021.04.012}, pages = {2170 -- 2178}, year = {2021}, abstract = {Mining of metabolite-protein interaction networks facilitates the identification of design principles underlying the regulation of different cellular processes. However, identification and characterization of the regulatory role that metabolites play in interactions with proteins on a genome-scale level remains a pressing task. Based on availability of high-quality metabolite-protein interaction networks and genome-scale metabolic networks, here we propose a supervised machine learning approach, called CIRI that determines whether or not a metabolite is involved in a competitive inhibitory regulatory interaction with an enzyme. First, we show that CIRI outperforms the naive approach based on a structural similarity threshold for a putative competitive inhibitor and the substrates of a metabolic reaction. We also validate the performance of CIRI on several unseen data sets and databases of metabolite-protein interactions not used in the training, and demonstrate that the classifier can be effectively used to predict competitive inhibitory interactions. Finally, we show that CIRI can be employed to refine predictions about metabolite-protein interactions from a recently proposed PROMIS approach that employs metabolomics and proteomics profiles from size exclusion chromatography in E. coli to predict metaboliteprotein interactions. Altogether, CIRI fills a gap in cataloguing metabolite-protein interactions and can be used in directing future machine learning efforts to categorize the regulatory type of these interactions.}, language = {en} } @article{CampbellKairaliyevaSanteretal.2022, author = {Campbell, Richard and Kairaliyeva, Talmira and Santer, Svetlana and Schneck, Emanuel and Miller, Reinhard}, title = {Direct resolution of the interactions of a hydrocarbon gas with adsorbed surfactant monolayers at the water/air interface using neutron reflectometry}, series = {Colloids and interfaces}, volume = {6}, journal = {Colloids and interfaces}, number = {4}, publisher = {MDPI}, address = {Basel}, issn = {2504-5377}, doi = {10.3390/colloids6040068}, pages = {12}, year = {2022}, abstract = {We have directly resolved in the present work the interfacial composition during and after the interactions of a saturated atmosphere of oil vapor with soluble surfactant solutions at a planar water/air interface for the first time. Experiments were conducted on interactions of hexane vapor with solutions of alkyltrimethylammonium bromides and sodium dodecyl sulfate to observe the balance between cooperativity and competition of the components at the interface. In all cases, hexane adsorption was strongly enhanced by the presence of the surfactant, even at bulk surfactant concentrations four orders of magnitude below the critical micelle concentration. Cooperativity of the surfactant adsorption was observed only for sodium dodecyl sulfate at intermediate bulk concentrations, yet for all four systems, competition set in at higher concentrations, as hexane adsorption reduced the surfactant surface excess. The data fully supported the complete removal of hexane from the interface following venting of the system to remove the saturated atmosphere of oil vapor. These results help to identify future experiments that would elaborate and could explain the cooperativity of surfactant adsorption, such as on cationic surfactants with short alkyl chains and a broader series of anionic surfactants. This work holds relevance for oil recovery applications with foam, where there is a gas phase saturated with oil vapor.}, language = {en} } @article{ShoghiArslanBastiaanseetal.2022, author = {Shoghi, Sara and Arslan, Seckin and Bastiaanse, Roelien and Popov, Srdan}, title = {Does a walk-through video help the parser down the garden-path?}, series = {Frontiers in psychology}, volume = {13}, journal = {Frontiers in psychology}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {1664-1078}, doi = {10.3389/fpsyg.2022.1009265}, pages = {14}, year = {2022}, abstract = {The human language processing mechanism assigns a structure to the incoming materials as they unfold. There is evidence that the parser prefers some attachment types over others; however, theories of sentence processing are still in dispute over the stage at which each source of information contributes to the parsing system. The present study aims to identify the nature of initial parsing decisions during sentence processing through manipulating attachment type and verbs' argument structure. To this end, we designed a self-paced reading task using globally ambiguous constructions in Dutch. The structures included double locative prepositional phrases (PPs) where the first PP could attach both to the verb (high attachment) and the noun preceding it (low attachment). To disambiguate the structures, we presented a visual context in the form of short animation clips prior to each reading task. Furthermore, we manipulated the argument structure of the sentences using 2- and 3-argument verbs. The results showed that parsing decisions were influenced by contextual cues depending on the argument structure of the verb. That is, the visual context overcame the preference for high attachment only in the case of 2-argument verbs, while this preference persisted in structures including 3-argument verbs as represented by longer reading times for the low attachment interpretations. These findings can be taken as evidence that our language processing system actively integrates information from linguistic and non-linguistic sources from the initial stages of analysis to build up meaning. We discuss our findings in light of serial and parallel models of sentence processing.}, language = {en} } @article{HabelSchmittGrosetal.2022, author = {Habel, Jan Christian and Schmitt, Thomas and Gros, Patrick and Ulrich, Werner}, title = {Breakpoints in butterfly decline in Central Europe over the last century}, series = {The science of the total environment : an international journal for scientific research into the environment and its relationship with man}, volume = {851}, journal = {The science of the total environment : an international journal for scientific research into the environment and its relationship with man}, number = {Part 2}, publisher = {Elsevier Science}, address = {Amsterdam}, issn = {0048-9697}, doi = {10.1016/j.scitotenv.2022.158315}, pages = {9}, year = {2022}, abstract = {Recent studies indicated severe decline of insect diversity and abundance across major parts of Central Europe. Theoretical studies showed that the drivers behind biodiversity loss vary considerably over time. However, these scenarios so far have been insufficiently approved by long-term and large-scale data. In this study we analysed the temporal trends of butterflies and Zygaenid moths across the federal state of Salzburg, northern Austria, from 1920 to 2019. Our study area covers a large variety of habitats and altitudes. Various changes of land use and intensification occurred during and shortly before our studied period, with a first wave of habitat destruction starting in the late 19th century, followed by the deterioration of habitat quality since the mid-20th century. We used 59,870 presence-only data of 168 butterfly and burnet moth species. Each of these species was classified according to ecological characteristics. Break point analyses for non-linear temporal trends in the community composition returned two major time windows. These time windows coincide with periods characterized by severe habitat destruction and the deterioration of habitat quality due to agricultural intensification. We found significant reductions of the proportion of species requiring specific habitats since 1920 and until today. We identified additional break points for species requiring high habitat qualities, endangered butterfly species, and sedentary species, particularly after a main break point in the 1960s. Our findings underline that, apart from habitat destruction, the deterioration of habitat quality is a main driver of biodiversity loss in general. Therefore, nature conservation should focus on maintaining the highest possible habitat quality.}, language = {en} }