@phdthesis{Vossenkuhl2015, author = {Vossenkuhl, Birgit}, title = {Transmission of MRSA along the meat supply chain}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-85918}, school = {Universit{\"a}t Potsdam}, pages = {141}, year = {2015}, abstract = {Methicillin-resistente Staphylococcus aureus (MRSA) z{\"a}hlen zu den bedeutendsten antibiotikaresistenten Pathogenen, die vor allem in Krankenh{\"a}usern aber auch außerhalb von Einrichtungen des Gesundheitswesens weit verbreitet sind. Seit einigen Jahren ist eine neue Generation von MRSA auf dem Vormarsch, die vor allem Nutztierbest{\"a}nde als neue Nische besiedelt. Diese sogenannten Nutztier-assoziierten MRSA wurden wiederholt bei wirtschaftlich bedeutenden Nutztieren sowie daraus gewonnenem Fleisch nachgewiesen. Im Rahmen der vorliegenden Arbeit wurde ein methodischer Ansatz verfolgt, um die Hypothese einer m{\"o}glichen {\"U}bertragung von Nutztier-assoziierten MRSA entlang der Lebensmittelkette vom Tier auf dessen Fleisch zu best{\"a}tigen. Angepasst an die Unterschiede in den verf{\"u}gbaren Daten wurden daf{\"u}r zwei neue Konzepte erstellt. Zur Analyse der {\"U}bertragung von MRSA entlang der Schlachtkette wurde ein mathematisches Modell des Schweineschlachtprozesses entwickelt, welches dazu geeignet ist, den Verlauf der MRSA-Pr{\"a}valenz entlang der Schlachtkette zu quantifizieren sowie kritische Prozessschritte f{\"u}r eine MRSA-{\"U}bertragung zu identifizieren. Anhand von Pr{\"a}valenzdaten ist es dem Modell m{\"o}glich, die durchschnittlichen MRSA-Eliminations- und Kontaminationsraten jedes einzelnen Prozessschrittes zu sch{\"a}tzen, die anschließend in eine Monte-Carlo-Simulation einfließen. Im Ergebnis konnte gezeigt werden, dass es generell m{\"o}glich ist, die MRSA Pr{\"a}valenz im Laufe des Schlachtprozesses auf ein niedriges finales Niveau zwischen 0,15 bis 1,15\% zu reduzieren. Vor allem das Br{\"u}hen und Abfl{\"a}mmen der Schlachtk{\"o}rper wurden als kritische Prozesse im Hinblick auf eine MRSA-Dekontamination identifiziert. In Deutschland werden regelm{\"a}ßig MRSA-Pr{\"a}valenz und Typisierungsdaten auf allen Stufen der Lebensmittelkette verschiedener Nutztiere erfasst. Um die MRSA-Daten dieser Querschnittstudie hinsichtlich einer m{\"o}glichen {\"U}bertragung entlang der Kette zu analysieren, wurde ein neuer statistischer Ansatz entwickelt. Hierf{\"u}r wurde eine Chi-Quadrat-Statistik mit der Berechnung des Czekanowski-{\"A}hnlichkeitsindex kombiniert, um Unterschiede in der Verteilung stammspezifischer Eigenschaften zwischen MRSA aus dem Stall, von Karkassen nach der Schlachtung und aus Fleisch im Einzelhandel zu quantifizieren. Die Methode wurde am Beispiel der Putenfleischkette implementiert und zudem bei der Analyse der Kalbfleischkette angewendet. Die durchgehend hohen {\"A}hnlichkeitswerte zwischen den einzelnen Proben weisen auf eine m{\"o}gliche {\"U}bertragung von MRSA entlang der Lebensmittelkette hin. Die erarbeiteten Methoden sind nicht spezifisch bez{\"u}glich Prozessketten und Pathogenen. Sie bieten somit einen großen Anwendungsbereich und erweitern das Methodenspektrum zur Bewertung bakterieller {\"U}bertragungswege.}, language = {en} } @phdthesis{Spooner2021, author = {Spooner, Cameron}, title = {How does lithospheric configuration relate to deformation in the Alpine region?}, doi = {10.25932/publishup-51644}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-516442}, school = {Universit{\"a}t Potsdam}, pages = {xiv, 138}, year = {2021}, abstract = {Forming as a result of the collision between the Adriatic and European plates, the Alpine orogen exhibits significant lithospheric heterogeneity due to the long history of interplay between these plates, other continental and oceanic blocks in the region, and inherited features from preceeding orogenies. This implies that the thermal and rheological configuration of the lithosphere also varies significantly throughout the region. Lithology and temperature/pressure conditions exert a first order control on rock strength, principally via thermally activated creep deformation and on the distribution at depth of the brittle-ductile transition zone, which can be regarded as the lower bound to the seismogenic zone. Therefore, they influence the spatial distribution of seismicity within a lithospheric plate. In light of this, accurately constrained geophysical models of the heterogeneous Alpine lithospheric configuration, are crucial in describing regional deformation patterns. However, despite the amount of research focussing on the area, different hypotheses still exist regarding the present-day lithospheric state and how it might relate to the present-day seismicity distribution. This dissertaion seeks to constrain the Alpine lithospheric configuration through a fully 3D integrated modelling workflow, that utilises multiple geophysical techniques and integrates from all available data sources. The aim is therefore to shed light on how lithospheric heterogeneity may play a role in influencing the heterogeneous patterns of seismicity distribution observed within the region. This was accomplished through the generation of: (i) 3D seismically constrained, structural and density models of the lithosphere, that were adjusted to match the observed gravity field; (ii) 3D models of the lithospheric steady state thermal field, that were adjusted to match observed wellbore temperatures; and (iii) 3D rheological models of long term lithospheric strength, with the results of each step used as input for the following steps. Results indicate that the highest strength within the crust (~ 1 GPa) and upper mantle (> 2 GPa), are shown to occur at temperatures characteristic for specific phase transitions (more felsic crust: 200 - 400 °C; more mafic crust and upper lithospheric mantle: ~600 °C) with almost all seismicity occurring in these regions. However, inherited lithospheric heterogeneity was found to significantly influence this, with seismicity in the thinner and more mafic Adriatic crust (~22.5 km, 2800 kg m-3, 1.30E-06 W m-3) occuring to higher temperatures (~600 °C) than in the thicker and more felsic European crust (~27.5 km, 2750 kg m-3, 1.3-2.6E-06 W m-3, ~450 °C). Correlation between seismicity in the orogen forelands and lithospheric strength, also show different trends, reflecting their different tectonic settings. As such, events in the plate boundary setting of the southern foreland correlate with the integrated lithospheric strength, occurring mainly in the weaker lithosphere surrounding the strong Adriatic indenter. Events in the intraplate setting of the northern foreland, instead correlate with crustal strength, mainly occurring in the weaker and warmer crust beneath the Upper Rhine Graben. Therefore, not only do the findings presented in this work represent a state of the art understanding of the lithospheric configuration beneath the Alps and their forelands, but also a significant improvement on the features known to significantly influence the occurrence of seismicity within the region. This highlights the importance of considering lithospheric state in regards to explaining observed patterns of deformation.}, language = {en} } @phdthesis{Smirnov2011, author = {Smirnov, Sergey}, title = {Business process model abstraction}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-60258}, school = {Universit{\"a}t Potsdam}, year = {2011}, abstract = {Business process models are used within a range of organizational initiatives, where every stakeholder has a unique perspective on a process and demands the respective model. As a consequence, multiple process models capturing the very same business process coexist. Keeping such models in sync is a challenge within an ever changing business environment: once a process is changed, all its models have to be updated. Due to a large number of models and their complex relations, model maintenance becomes error-prone and expensive. Against this background, business process model abstraction emerged as an operation reducing the number of stored process models and facilitating model management. Business process model abstraction is an operation preserving essential process properties and leaving out insignificant details in order to retain information relevant for a particular purpose. Process model abstraction has been addressed by several researchers. The focus of their studies has been on particular use cases and model transformations supporting these use cases. This thesis systematically approaches the problem of business process model abstraction shaping the outcome into a framework. We investigate the current industry demand in abstraction summarizing it in a catalog of business process model abstraction use cases. The thesis focuses on one prominent use case where the user demands a model with coarse-grained activities and overall process ordering constraints. We develop model transformations that support this use case starting with the transformations based on process model structure analysis. Further, abstraction methods considering the semantics of process model elements are investigated. First, we suggest how semantically related activities can be discovered in process models-a barely researched challenge. The thesis validates the designed abstraction methods against sets of industrial process models and discusses the method implementation aspects. Second, we develop a novel model transformation, which combined with the related activity discovery allows flexible non-hierarchical abstraction. In this way this thesis advocates novel model transformations that facilitate business process model management and provides the foundations for innovative tool support.}, language = {en} } @article{MeierFast2008, author = {Meier, Bernd and Fast, Ludger}, title = {{\"U}ber Technik kommunizieren}, series = {Unterricht: Arbeit + Technik}, volume = {10}, journal = {Unterricht: Arbeit + Technik}, number = {39}, issn = {1438-8987}, pages = {25 -- 44}, year = {2008}, abstract = {Die Unterrichtsmaterialien des Einhefters vermitteln Einblicke in den Aufbau und die Funktion der technischen Systeme von Brotschneidemaschine, Handr{\"u}hrger{\"a}t, Eierkocher, Elektroherd, K{\"u}hlschrank, Gefrierschrank, Akkusauger und elektrischem K{\"u}chenmesser. Dabei wird z. T. eine Demontage bzw. Remontage durchgef{\"u}hrt. Des weiteren werden die Stoff-, Energie- und Informationsums{\"a}tze der technischen Systeme behandelt, letztere werden analysiert und systematisiert, bevor die Sch{\"u}lerinnen und Sch{\"u}ler Funktionsmodelle bauen k{\"o}nnen.}, language = {de} } @phdthesis{Krummenauer2022, author = {Krummenauer, Linda}, title = {Global heat adaptation among urban populations and its evolution under different climate futures}, doi = {10.25932/publishup-55929}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-559294}, school = {Universit{\"a}t Potsdam}, pages = {xix, 161}, year = {2022}, abstract = {Heat and increasing ambient temperatures under climate change represent a serious threat to human health in cities. Heat exposure has been studied extensively at a global scale. Studies comparing a defined temperature threshold with the future daytime temperature during a certain period of time, had concluded an increase in threat to human health. Such findings however do not explicitly account for possible changes in future human heat adaptation and might even overestimate heat exposure. Thus, heat adaptation and its development is still unclear. Human heat adaptation refers to the local temperature to which populations are adjusted to. It can be inferred from the lowest point of the U- or V-shaped heat-mortality relationship (HMR), the Minimum Mortality Temperature (MMT). While epidemiological studies inform on the MMT at the city scale for case studies, a general model applicable at the global scale to infer on temporal change in MMTs had not yet been realised. The conventional approach depends on data availability, their robustness, and on the access to daily mortality records at the city scale. Thorough analysis however must account for future changes in the MMT as heat adaptation happens partially passively. Human heat adaptation consists of two aspects: (1) the intensity of the heat hazard that is still tolerated by human populations, meaning the heat burden they can bear and (2) the wealth-induced technological, social and behavioural measures that can be employed to avoid heat exposure. The objective of this thesis is to investigate and quantify human heat adaptation among urban populations at a global scale under the current climate and to project future adaptation under climate change until the end of the century. To date, this has not yet been accomplished. The evaluation of global heat adaptation among urban populations and its evolution under climate change comprises three levels of analysis. First, using the example of Germany, the MMT is calculated at the city level by applying the conventional method. Second, this thesis compiles a data pool of 400 urban MMTs to develop and train a new model capable of estimating MMTs on the basis of physical and socio-economic city characteristics using multivariate non-linear multivariate regression. The MMT is successfully described as a function of the current climate, the topography and the socio-economic standard, independently of daily mortality data for cities around the world. The city-specific MMT estimates represents a measure of human heat adaptation among the urban population. In a final third analysis, the model to derive human heat adaptation was adjusted to be driven by projected climate and socio-economic variables for the future. This allowed for estimation of the MMT and its change for 3 820 cities worldwide for different combinations of climate trajectories and socio-economic pathways until 2100. The knowledge on the evolution of heat adaptation in the future is a novelty as mostly heat exposure and its future development had been researched. In this work, changes in heat adaptation and exposure were analysed jointly. A wide range of possible health-related outcomes up to 2100 was the result, of which two scenarios with the highest socio-economic developments but opposing strong warming levels were highlighted for comparison. Strong economic growth based upon fossil fuel exploitation is associated with a high gain in heat adaptation, but may not be able to compensate for the associated negative health effects due to increased heat exposure in 30\% to 40\% of the cities investigated caused by severe climate change. A slightly less strong, but sustainable growth brings moderate gains in heat adaptation but a lower heat exposure and exposure reductions in 80\% to 84\% of the cities in terms of frequency (number of days exceeding the MMT) and intensity (magnitude of the MMT exceedance) due to a milder global warming. Choosing a 2 ° C compatible development by 2100 would therefore lower the risk of heat-related mortality at the end of the century. In summary, this thesis makes diverse and multidisciplinary contributions to a deeper understanding of human adaptation to heat under the current and the future climate. It is one of the first studies to carry out a systematic and statistical analysis of urban characteristics which are useful as MMT drivers to establish a generalised model of human heat adaptation, applicable at the global level. A broad range of possible heat-related health options for various future scenarios was shown for the first time. This work is of relevance for the assessment of heat-health impacts in regions where mortality data are not accessible or missing. The results are useful for health care planning at the meso- and macro-level and to urban- and climate change adaptation planning. Lastly, beyond having met the posed objective, this thesis advances research towards a global future impact assessment of heat on human health by providing an alternative method of MMT estimation, that is spatially and temporally flexible in its application.}, language = {en} } @phdthesis{Holz2013, author = {Holz, Christian}, title = {3D from 2D touch}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-67796}, school = {Universit{\"a}t Potsdam}, year = {2013}, abstract = {While interaction with computers used to be dominated by mice and keyboards, new types of sensors now allow users to interact through touch, speech, or using their whole body in 3D space. These new interaction modalities are often referred to as "natural user interfaces" or "NUIs." While 2D NUIs have experienced major success on billions of mobile touch devices sold, 3D NUI systems have so far been unable to deliver a mobile form factor, mainly due to their use of cameras. The fact that cameras require a certain distance from the capture volume has prevented 3D NUI systems from reaching the flat form factor mobile users expect. In this dissertation, we address this issue by sensing 3D input using flat 2D sensors. The systems we present observe the input from 3D objects as 2D imprints upon physical contact. By sampling these imprints at very high resolutions, we obtain the objects' textures. In some cases, a texture uniquely identifies a biometric feature, such as the user's fingerprint. In other cases, an imprint stems from the user's clothing, such as when walking on multitouch floors. By analyzing from which part of the 3D object the 2D imprint results, we reconstruct the object's pose in 3D space. While our main contribution is a general approach to sensing 3D input on 2D sensors upon physical contact, we also demonstrate three applications of our approach. (1) We present high-accuracy touch devices that allow users to reliably touch targets that are a third of the size of those on current touch devices. We show that different users and 3D finger poses systematically affect touch sensing, which current devices perceive as random input noise. We introduce a model for touch that compensates for this systematic effect by deriving the 3D finger pose and the user's identity from each touch imprint. We then investigate this systematic effect in detail and explore how users conceptually touch targets. Our findings indicate that users aim by aligning visual features of their fingers with the target. We present a visual model for touch input that eliminates virtually all systematic effects on touch accuracy. (2) From each touch, we identify users biometrically by analyzing their fingerprints. Our prototype Fiberio integrates fingerprint scanning and a display into the same flat surface, solving a long-standing problem in human-computer interaction: secure authentication on touchscreens. Sensing 3D input and authenticating users upon touch allows Fiberio to implement a variety of applications that traditionally require the bulky setups of current 3D NUI systems. (3) To demonstrate the versatility of 3D reconstruction on larger touch surfaces, we present a high-resolution pressure-sensitive floor that resolves the texture of objects upon touch. Using the same principles as before, our system GravitySpace analyzes all imprints and identifies users based on their shoe soles, detects furniture, and enables accurate touch input using feet. By classifying all imprints, GravitySpace detects the users' body parts that are in contact with the floor and then reconstructs their 3D body poses using inverse kinematics. GravitySpace thus enables a range of applications for future 3D NUI systems based on a flat sensor, such as smart rooms in future homes. We conclude this dissertation by projecting into the future of mobile devices. Focusing on the mobility aspect of our work, we explore how NUI devices may one day augment users directly in the form of implanted devices.}, language = {en} } @phdthesis{Fischer2014, author = {Fischer, Jost Leonhardt}, title = {Nichtlineare Kopplungsmechanismen akustischer Oszillatoren am Beispiel der Synchronisation von Orgelpfeifen}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-71975}, school = {Universit{\"a}t Potsdam}, year = {2014}, abstract = {In dieser Arbeit werden nichtlineare Kopplungsmechanismen von akustischen Oszillatoren untersucht, die zu Synchronisation f{\"u}hren k{\"o}nnen. Aufbauend auf die Fragestellungen vorangegangener Arbeiten werden mit Hilfe theoretischer und experimenteller Studien sowie mit Hilfe numerischer Simulationen die Elemente der Tonentstehung in der Orgelpfeife und die Mechanismen der gegenseitigen Wechselwirkung von Orgelpfeifen identifiziert. Daraus wird erstmalig ein vollst{\"a}ndig auf den aeroakustischen und fluiddynamischen Grundprinzipien basierendes nichtlinear gekoppeltes Modell selbst-erregter Oszillatoren f{\"u}r die Beschreibung des Verhaltens zweier wechselwirkender Orgelpfeifen entwickelt. Die durchgef{\"u}hrten Modellrechnungen werden mit den experimentellen Befunden verglichen. Es zeigt sich, dass die Tonentstehung und die Kopplungsmechanismen von Orgelpfeifen durch das entwickelte Oszillatormodell in weiten Teilen richtig beschrieben werden. Insbesondere kann damit die Ursache f{\"u}r den nichtlinearen Zusammenhang von Kopplungsst{\"a}rke und Synchronisation des gekoppelten Zwei-Pfeifen Systems, welcher sich in einem nichtlinearen Verlauf der Arnoldzunge darstellt, gekl{\"a}rt werden. Mit den gewonnenen Erkenntnissen wird der Einfluss des Raumes auf die Tonentstehung bei Orgelpfeifen betrachtet. Daf{\"u}r werden numerische Simulationen der Wechselwirkung einer Orgelpfeife mit verschiedenen Raumgeometrien, wie z. B. ebene, konvexe, konkave, und gezahnte Geometrien, exemplarisch untersucht. Auch der Einfluss von Schwellk{\"a}sten auf die Tonentstehung und die Klangbildung der Orgelpfeife wird studiert. In weiteren, neuartigen Synchronisationsexperimenten mit identisch gestimmten Orgelpfeifen, sowie mit Mixturen wird die Synchronisation f{\"u}r verschiedene, horizontale und vertikale Pfeifenabst{\"a}nde in der Ebene der Schallabstrahlung, untersucht. Die dabei erstmalig beobachteten r{\"a}umlich isotropen Unstetigkeiten im Schwingungsverhalten der gekoppelten Pfeifensysteme, deuten auf abstandsabh{\"a}ngige Wechsel zwischen gegen- und gleichphasigen Sychronisationsregimen hin. Abschließend wird die M{\"o}glichkeit dokumentiert, das Ph{\"a}nomen der Synchronisation zweier Orgelpfeifen durch numerische Simulationen, also der Behandlung der kompressiblen Navier-Stokes Gleichungen mit entsprechenden Rand- und Anfangsbedingungen, realit{\"a}tsnah abzubilden. Auch dies stellt ein Novum dar.}, language = {de} } @phdthesis{Buchmann2012, author = {Buchmann, Carsten M.}, title = {Modelling the structuring of animal communities in heterogeneous landscapes : the role of individual home range formation, foraging movement, competition and habitat configuration}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-59031}, school = {Universit{\"a}t Potsdam}, year = {2012}, abstract = {This thesis aims at a better mechanistic understanding of animal communities. Therefore, an allometry- and individual-based model has been developed which was used to simulate mammal and bird communities in heterogeneous landscapes, and to to better understand their response to landscape changes (habitat loss and fragmentation).}, language = {en} }