@article{FujikuraJingHanadaetal.2018,
  author    = {Fujikura, Ushio and Jing, Runchun and Hanada, Atsushi and Takebayashi, Yumiko and Sakakibara, Hitoshi and Yamaguchi, Shinjiro and Kappel, Christian and Lenhard, Michael},
  title     = {Variation in splicing efficiency underlies morphological evolution in capsella},
  series = {Developmental cell},
  volume    = {44},
  journal   = {Developmental cell},
  number    = {2},
  publisher = {Cell Press},
  address   = {Cambridge},
  issn      = {1534-5807},
  doi       = {10.1016/j.devcel.2017.11.022},
  pages     = {192 -- 203},
  year      = {2018},
  abstract  = {Understanding the molecular basis of morphological change remains a central challenge in evolutionary-developmental biology. The transition from outbreeding to selfing is often associated with a dramatic reduction in reproductive structures and functions, such as the loss of attractive pheromones in hermaphroditic Caenorhabditis elegans and a reduced flower size in plants. Here, we demonstrate that variation in the level of the brassinosteroid-biosynthesis enzyme CYP724A1 contributes to the reduced flower size of selfing Capsella rubella compared with its outbreeding ancestor Capsella grandiflora. The primary transcript of the C. rubella allele is spliced more efficiently than that of C. grandiflora, resulting in higher brassinosteroid levels. These restrict organ growth by limiting cell proliferation. More efficient splicing of the C. rubella allele results from two de novo mutations in the selfing lineage. Thus, our results highlight the potentially widespread importance of differential splicing efficiency and higher-than-optimal hormone levels in generating phenotypic variation.},
  language  = {en}
}
@article{LohmannStaceyBreuningeretal.2010,
  author    = {Lohmann, Daniel and Stacey, Nicola and Breuninger, Holger and Jikumaru, Yusuke and M{\"u}ller, D{\"o}rte and Sicard, Adrien and Leyser, Ottoline and Yamaguchi, Shinjiro and Lenhard, Michael},
  title     = {SLOW MOTION is required for within-plant auxin homeostasis and normal timing of lateral organ initiation at the shoot meristem in Arabidopsis},
  issn      = {1040-4651},
  year      = {2010},
  language  = {en}
}