@misc{NguyenRichertParketal.2017, author = {Nguyen, Vu Hoa and Richert, S. and Park, Hyunji and B{\"o}ker, Alexander and Schnakenberg, Uwe}, title = {Single interdigital transducer as surface acoustic wave impedance sensor}, series = {Biosensors}, volume = {27}, journal = {Biosensors}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2212-0173}, doi = {10.1016/j.protcy.2017.04.032}, pages = {70 -- 71}, year = {2017}, abstract = {Surface acoustic wave (SAW) devices are well-known for gravimetric sensor applications. In biosensing applications, chemical-and biochemically evoked adsorption processes at surfaces are detected in liquid environments using delay-line or resonator sensor configurations, preferably in combination with appropriate microfluidic devices. In this paper, a novel SAW-based impedance sensor type is introduced which uses only one interdigital electrode transducer (IDT) simultaneously as SAW generator and sensor element. It is shown that the amplitude of the reflected S-11 signal directly depends on the input impedance of the SAW device. The input impedance is strongly influenced by mass adsorption which causes a characteristic and measurable impedance mismatch.}, language = {en} } @misc{HessWirtzAllroggenetal.2017, author = {Hess, Markus and Wirtz, Susanne and Allroggen, Marc and Scheithauer, Herbert}, title = {Intervention und Therapie f{\"u}r T{\"a}ter und Opfer von Schulbullying}, series = {Praxis der Kinderpsychologie und Kinderpsychiatrie : Ergebnisse aus Psychotherapie, Beratung und Psychiatrie}, volume = {66}, journal = {Praxis der Kinderpsychologie und Kinderpsychiatrie : Ergebnisse aus Psychotherapie, Beratung und Psychiatrie}, number = {10}, publisher = {Vandenhoeck \& Ruprecht}, address = {G{\"o}ttingen}, issn = {0032-7034}, doi = {10.13109/prkk.2017.66.10.740}, pages = {740 -- 755}, year = {2017}, abstract = {Bullying ist eine Form wiederholten, aggressiven Verhaltens mit ernstzunehmenden Auswirkungen, unter denen T{\"a}ter und Opfer h{\"a}ufig lange nach Ende des Bullying-Geschehens leiden. Dennoch ist die Therapie von Bullying und den damit einhergehenden Folgen ein bisher in der Forschung vernachl{\"a}ssigtes Thema. Im Rahmen eines systematischen Literatur{\"u}berblicks wurde daher untersucht, welche Therapieformen zur Behandlung von Bullying und dessen Folgen bei Opfern und bei T{\"a}tern bereits angewendet wurden. Eine systematische Suche in nationalen und internationalen Datenbanken f{\"u}hrte zu 31 relevanten Publikationen, in denen 34 therapeutische Interventionen aus {\"u}ber 14 L{\"a}ndern beschrieben wurden. In zehn Therapiestudien mit kontrolliertem Design zeigte sich, dass Behandlungsangebote, die sich sowohl an die betroffenen Personen als auch an ihr soziales Umfeld richten, besonders effektiv in der Behandlung von Bullying-Folgen sind. Die restlichen 24 Behandlungsans{\"a}tze wurden keiner kontrollierten Evaluation unterzogen. Insgesamt zwei Drittel aller therapeutischen Interventionen wenden sich an die Gruppe der Opfer. Hier wird im Unterschied zur Behandlung von T{\"a}tern verst{\"a}rkt auf Gruppentherapien zur{\"u}ckgegriffen. Unter der Bandbreite an Ans{\"a}tzen ist die kognitive Verhaltenstherapie am h{\"a}ufigsten vertreten. Festzustellen bleibt ein Forschungsmangel an evidenzbasierten, gezielten Interventionen zur Behandlung von Bullying und dessen Folgen bei Opfern und T{\"a}tern. Unseres Wissens stellt diese Arbeit den ersten systematischen {\"U}berblick zu therapeutischen Interventionen bei Bullying f{\"u}r Kinder und Jugendliche dar.}, language = {de} } @misc{SchmidtHattenbergerBergmannLabitzkeetal.2017, author = {Schmidt-Hattenberger, Cornelia and Bergmann, Peter and Labitzke, Tim and Pommerencke, Julia and Rippe, Dennis and Wagner, Florian and Wiese, Bernd}, title = {Monitoring the complete life-cycle of a CO2 storage reservoir-Demonstration of applicability of geoelectrical imaging}, series = {13th International Conference on Greenhouse Gas Control Technologies (GHGT)}, volume = {114}, journal = {13th International Conference on Greenhouse Gas Control Technologies (GHGT)}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1876-6102}, doi = {10.1016/j.egypro.2017.03.1526}, pages = {3948 -- 3955}, year = {2017}, abstract = {In this paper, the applicability of deep downhole geoelectrical monitoring for detecting CO2 related signatures is evaluated after a nearly ten year period of CO2 storage at the Ketzin pilot site. Deep downhole electrode arrays have been studied as part of a multi-physical monitoring concept at four CO2 pilot test sites worldwide so far. For these sites, it was considered important to implement the geoelectrical method into the measurement program of tracking the CO2 plume. Analyzing the example of the Ketzin site, it can be seen that during all phases of the CO2 storage reservoir development the resistivity measurements and their corresponding tomographic interpretation contribute in a beneficial manner to the measurement, monitoring and verification (MMV) protocol. The most important impact of a permanent electrode array is its potential as tool for estimating reservoir saturations.}, language = {en} } @article{AlAni2017, author = {Al-Ani, Ayad}, title = {CPS and the Worker}, series = {Industrial Internet of Things : Cybermanufacturing Systems}, journal = {Industrial Internet of Things : Cybermanufacturing Systems}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-42559-7}, issn = {2365-4139}, doi = {10.1007/978-3-319-42559-7_23}, pages = {563 -- 574}, year = {2017}, abstract = {The idea of interlinked, sensor-augmented, self-governing Cyber Physical System (CPS) production processes is gaining momentum. At the same time, the impact of this concept on the workforce remains surprisingly vague. This can be explained by the fact that man is not at the centre of these developments and—even more importantly—automation is geared towards eliminating human activity. Based on the first views in the 1980s, the label of the "process worker" assumed an almost exclusive focus on control and maintenance tasks for this new type of worker in the automated factory. Recent experiences show, however, that as long as robots are not self-learning, man will be the template for these machines and we can already notice the emerging parallelism of fully automated production lines and human workshops. The changing nature of the workforce will gain further momentum if one depicts new, open formats of production. Here, the worker will have to assume new roles in reconfiguring the production processes.}, language = {en} } @article{NeuberSchumacherGulbinsetal.2017, author = {Neuber, Corinna and Schumacher, Fabian and Gulbins, Erich and Kleuser, Burkhard}, title = {Mass Spectrometric Determination of Fatty Aldehydes Exemplified by Monitoring the Oxidative Degradation of (2E)-Hexadecenal in HepG2 Cell Lysates}, series = {Lipidomics}, volume = {125}, journal = {Lipidomics}, publisher = {Humana Press}, address = {Totowa}, isbn = {978-1-4939-6946-3}, issn = {0893-2336}, doi = {10.1007/978-1-4939-6946-3_10}, pages = {147 -- 158}, year = {2017}, abstract = {Within the last few decades, liquid chromatography-mass spectrometry (LC-MS) has become a preferred method for manifold issues in analytical biosciences, given its high selectivity and sensitivity. However, the analysis of fatty aldehydes, which are important components of cell metabolism, remains challenging. Usually, chemical derivatization prior to MS detection is required to enhance ionization efficiency. In this regard, the coupling of fatty aldehydes to hydrazines like 2,4-dinitrophenylhydrazine (DNPH) is a common approach. Additionally, hydrazones readily react with fatty aldehydes to form stable derivatives, which can be easily separated using high-performance liquid chromatography (HPLC) and subsequently detected by MS. Here, we exemplarily present the quantification of the long-chain fatty aldehyde (2E)-hexadecenal, a break-down product of the bioactive lipid sphingosine 1-phosphate (S1P), after derivatization with 2-diphenylacetyl-1,3-indandione-1-hydrazone (DAIH) via isotope-dilution HPLC-electrospray ionization-quadrupole/time-of-flight (ESI-QTOF) MS. Moreover, we show that the addition of N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC hydrochloride) as a coupling agent allows for simultaneous determination of fatty aldehydes and fatty acids as DAIH derivatives. Taking advantage of this, we describe in detail how to monitor the degradation of (2E)-hexadecenal and the concurrent formation of its oxidation product (2E)-hexadecenoic acid in lysates of human hepatoblastoma (HepG2) cells within this chapter.}, language = {en} } @article{CzernitzkiPospisilMusaleketal.2017, author = {Czernitzki, Anna-Franziska and Pospisil, Christina and Musalek, Martin and Mumm, Rebekka and Scheffler, Christiane}, title = {Analysis of longitudinal data of height z-scores in kindergarten children}, series = {Journal of biological and clinical anthropology : Anthropologischer Anzeiger ; Mitteilungsorgan der Gesellschaft f{\"u}r Anthropologie}, volume = {74}, journal = {Journal of biological and clinical anthropology : Anthropologischer Anzeiger ; Mitteilungsorgan der Gesellschaft f{\"u}r Anthropologie}, number = {2}, publisher = {Schweizerbart science publishers}, address = {Stuttgart}, issn = {0003-5548}, doi = {10.1127/anthranz/2017/0708}, pages = {109 -- 112}, year = {2017}, abstract = {Changes in body height throughout extended historic periods are very complex and dynamic processes. Thispilot study aimed to investigate the pattern of longitudinal height z-scores changes in children before and after entering kindergarten. In summer 2016, we measured height and weight of 32 children from 4 groups of two kindergartens aged 3-6 years. All ages were centered according to the age of entry into the kindergarten. For each child we determined mean z-scores for height before and after entering the kindergarten, and assessed the variances for each kindergarten group. Twenty-two children targeted in height z-scores towards average height of their respective kindergarten group, 10 children did not. Due to the small numbers, the convergence in height variance however, remained insignificant (chi-squared independence test, p = 0.127). Additional studies with larger sample sizes are needed to confirm this pilot study.}, language = {en} } @article{SchwiebsThomasKleuseretal.2017, author = {Schwiebs, Anja and Thomas, Dominique Jeanette and Kleuser, Burkhard and Pfeilschifter, Josef and Radeke, Heinfried H.}, title = {Nuclear translocation of SGPP-1 and decrease of SGPL-1 activity contribute to sphingolipid rheostat regulation of inflammatory dendritic cells}, series = {Mediators of inflammation}, journal = {Mediators of inflammation}, publisher = {Hindawi Publishing Corp.}, address = {London}, issn = {0962-9351}, doi = {10.1155/2017/5187368}, pages = {10}, year = {2017}, abstract = {A balanced sphingolipid rheostat is indispensable for dendritic cell function and survival and thus initiation of an immune response. Sphingolipid levels are dynamically maintained by the action of sphingolipid enzymes of which sphingosine kinases, S1P phosphatases (SGPP-1/2) and S1P lyase (SGPL-1), are pivotal in the balance of S1P and sphingosine levels. In this study, we present that SGPP-1 and SGPL-1 are regulated in inflammatory dendritic cells and contribute to S1P fate. TLR-dependent activation caused SGPL-1 protein downregulation with subsequent decrease of enzymatic activity by two-thirds. In parallel, confocal fluorescence microscopy revealed that endogenous SGPP-1 was expressed in nuclei of naive dendritic cells and was translocated into the cytoplasmatic compartment upon inflammatory stimulation resulting in dephosphorylation of S1P. Mass spectrometric determination showed that a part of the resulting sphingosine was released from the cell, increasing extracellular levels. Another route of diminishing intracellular S1P was possibly taken by its export via ATP-binding cassette transporter C1 which was upregulated in array analysis, while the S1P transporter, spinster homolog 2, was not relevant in dendritic cells. These investigations newly describe the sequential expression and localization of the endogenous S1P regulators SGPP-1 and SGPL-1 and highlight their contribution to the sphingolipid rheostat in inflammation.}, language = {en} } @article{YueAlterHowardetal.2017, author = {Yue, Jinxing and Alter, Kai-Uwe and Howard, David and Bastiaanse, Roelien}, title = {Early access to lexical-level phonological representations of Mandarin word-forms}, series = {Language, cognition and neuroscience}, volume = {32}, journal = {Language, cognition and neuroscience}, number = {9}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {2327-3798}, doi = {10.1080/23273798.2017.1290261}, pages = {1148 -- 1163}, year = {2017}, abstract = {An auditory habituation design was used to investigate whether lexical-level phonological representations in the brain can be rapidly accessed after the onset of a spoken word. We studied the N1 component of the auditory event-related electrical potential, and measured the amplitude decrements of N1 associated with the repetition of a monosyllabic tone word and an acoustically similar pseudo-word in Mandarin Chinese. Effects related to the contrastive onset consonants were controlled for by introducing two control words. We show that repeated pseudo-words consistently elicit greater amplitude decrements in N1 than real words. Furthermore, this lexicality effect is free from sensory fatigue or rapid learning of the pseudo-word. These results suggest that a lexical-level phonological representation of a spoken word can be accessed as early as 110ms after the onset of the word-form.}, language = {en} } @article{YouBehlLoewenbergetal.2017, author = {You, Zewang and Behl, Marc and L{\"o}wenberg, Candy and Lendlein, Andreas}, title = {pH-sensitivity and conformation change of the n-terminal methacrylated peptide VK20}, series = {MRS advances : a journal of the Materials Research Society (MRS)}, volume = {2}, journal = {MRS advances : a journal of the Materials Research Society (MRS)}, publisher = {Cambridge University Press}, address = {Cambridge}, issn = {2059-8521}, doi = {10.1557/adv.2017.491}, pages = {2571 -- 2579}, year = {2017}, abstract = {N-terminal methacrylation of peptide MAXI, which is capable of conformational changes variation of the pH, results in a peptide, named VK20. Increasing the reactivity of this terminal group enables further coupling reactions or chemical modifications of the peptidc. However, this end group functionalization may influence the ability of confonnational changes of VK20; as well as its properties. In this paper; the influence of pH on the transition between random coil and beta-sheet conformation of VK20; including the transition kinetics, were investigated. At pH values of 9 and higher, the kinetics beta-sheet formation increased tor VK(2 0, compared to MAXI. The self-assembly into beta-sheets recognized by the formation of a physically crosslinked gel was furthermore indicated by a significant increase of G. An increase in pH (from 9 to 9.5) led to a faster gelation of the peptide VK20. Simultaneously, G was increased from 460 +/- 70 Pa (at pH 9) to 1520 +/- 180 Pa (at pH 9.5). At the nanoscale, the gel showed a highly interconnected fibrillar/network structure with uniform fibril widths of approximately 3.4 +/- 0.5 nm (N=30). The recovery of the peptide conformation back to random coil resulted in the dissolution of the gel; whereby the kinetics of the recovery depended on the pH. Conclusively, the ability of MAXI to undergo confommtional changes was not affected by N-terminal methacrylation whereas the kinetics of pH-sensitive beta-sheet formations has been increased.}, language = {en} } @article{MuthauraKerikoMutaietal.2017, author = {Muthaura, Charles N. and Keriko, Joseph M. and Mutai, Charles and Yenesew, Abiy and Heydenreich, Matthias and Atilaw, Yoseph and Gathirwa, Jeremiah W. and Irungu, Beatrice N. and Derese, Solomon}, title = {Antiplasmodial, cytotoxicity and phytochemical constituents of four maytenus species used in traditional medicine in Kenya}, series = {The natural products journal}, volume = {7}, journal = {The natural products journal}, number = {2}, publisher = {Bentham Science Publ.}, address = {Sharjah}, issn = {2210-3155}, doi = {10.2174/2210315507666161206144050}, pages = {144 -- 152}, year = {2017}, abstract = {Background: In Kenya, several species of the genus Maytenus are used in traditional medicine to treat many diseases including malaria. In this study, phytochemical constituents and extracts of Maytenus undata, M. putterlickioides, M. senegalensis and M. heterophylla were evaluated to determine compound/s responsible for antimalarial activity. Objective: To isolate antiplasmodial compounds from these plant species which could be used as marker compounds in the standardization of their extracts as a phytomedicine for malaria. Methods: Constituents were isolated through activity-guided fractionation of the MeOH/CHCl3 (1:1) extracts and in vitro inhibition of Plasmodium falciparum. Cytotoxicity was evaluated using Vero cells and the compounds were elucidated on the basis of NMR spectroscopy. Results: Fractionation of the extracts resulted in the isolation of ten known compounds. Compound 1 showed promising antiplasmodial activity with IC50, 3.63 and 3.95 ng/ml against chloroquine sensitive (D6) and resistant (W2) P. falciparum, respectively and moderate cytotoxicity (CC50, 37.5 ng/ml) against Vero E6 cells. The other compounds showed weak antiplasmodial (IC50 > 1.93 mu g/ml) and cytotoxic (CC50 > 39.52 mu g/ml) activities against P. falciparum and Vero E6 cells, respectively. Conclusion: (20 alpha)-3-hydroxy-2-oxo-24-nor-friedela-1(10),3,5,7-tetraen-carboxylic acid-(29)-methyl-ester (pristimerin) (1) was the most active marker and lead compound that warrants further investigation as a template for the development of new antimalarial drugs. Pristimerin is reported for the first time in M. putterlickioides. 3-Hydroxyolean-12-en-28-oic acid (oleanolic acid) (5), stigmast-5-en-3-ol (beta-sitosterol) (6), 3-oxo-28-friedelanoic acid (7), olean-12-en-3-ol (beta-amyrin) (8), lup-20(29)-en-3-ol (lupeol) (9) and lup-20(29)-en-3-one (lupenone) (10) are reported for the first time in M. undata.}, language = {en} } @article{FyndanisLindVarlokostaetal.2017, author = {Fyndanis, Valantis and Lind, Marianne and Varlokosta, Spyridoula and Kambanaros, Maria and Soroli, Efstathia and Ceder, Klaudia and Grohmann, Kleanthes K. and Rofes, Adri{\`a} and Simonsen, Hanne Gram and Bjekić, Jovana and Gavarr{\´o}, Anna and Kraljević, Jelena Kuvač and Mart{\´i}nez-Ferreiro, Silvia and Munarriz, Amaia and Pourquie, Marie and Vuksanović, Jasmina and Zakari{\´a}s, Lilla and Howard, David}, title = {Cross-linguistic adaptations of The Comprehensive Aphasia Test}, series = {Clinical linguistics \& phonetics}, volume = {31}, journal = {Clinical linguistics \& phonetics}, number = {7-9}, publisher = {Taylor \& Francis Group}, address = {Philadelphia}, issn = {0269-9206}, doi = {10.1080/02699206.2017.1310299}, pages = {697 -- 710}, year = {2017}, abstract = {Comparative research on aphasia and aphasia rehabilitation is challenged by the lack of comparable assessment tools across different languages. In English, a large array of tools is available, while in most other languages, the selection is more limited. Importantly, assessment tools are often simple translations and do not take into consideration specific linguistic and psycholinguistic parameters of the target languages. As a first step in meeting the needs for comparable assessment tools, the Comprehensive Aphasia Test is currently being adapted into a number of languages spoken in Europe. In this article, some key challenges encountered in the adaptation process and the solutions to ensure that the resulting assessment tools are linguistically and culturally equivalent, are proposed. Specifically, we focus on challenges and solutions related to the use of imageability, frequency, word length, spelling-to-sound regularity and sentence length and complexity as underlying properties in the selection of the testing material.}, language = {en} } @article{ChangHedayatMahmoudiSchulze2017, author = {Chang, Der-Chen and Hedayat Mahmoudi, Mahdi and Schulze, Bert-Wolfgang}, title = {Singular degenerate operators}, series = {Applicable analysis : an international journal}, volume = {96}, journal = {Applicable analysis : an international journal}, number = {14}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {0003-6811}, doi = {10.1080/00036811.2017.1336546}, pages = {2434 -- 2456}, year = {2017}, abstract = {We outline some simplified and more general method for constructing parametrices on higher singular spaces. We also outline basic ideas on operators on manifolds with conical or edge singularities.}, language = {en} } @article{BaltaBeylergilBeckDesernoetal.2017, author = {Balta Beylergil, Sinem and Beck, Anne and Deserno, Lorenz and Lorenz, Robert C. and Rapp, Michael A. and Schlagenhauf, Florian and Heinz, Andreas and Obermayer, Klaus}, title = {Dorsolateral prefrontal cortex contributes to the impaired behavioral adaptation in alcohol dependence}, series = {NeuroImage: Clinical : a journal of diseases affecting the nervous system}, volume = {15}, journal = {NeuroImage: Clinical : a journal of diseases affecting the nervous system}, publisher = {Elsevier}, address = {Oxford}, issn = {2213-1582}, doi = {10.1016/j.nicl.2017.04.010}, pages = {80 -- 94}, year = {2017}, abstract = {Substance-dependent individuals often lack the ability to adjust decisions flexibly in response to the changes in reward contingencies. Prediction errors (PEs) are thought to mediate flexible decision-making by updating the reward values associated with available actions. In this study, we explored whether the neurobiological correlates of PEs are altered in alcohol dependence. Behavioral, and functional magnetic resonance imaging (fMRI) data were simultaneously acquired from 34 abstinent alcohol-dependent patients (ADP) and 26 healthy controls (HC) during a probabilistic reward-guided decision-making task with dynamically changing reinforcement contingencies. A hierarchical Bayesian inference method was used to fit and compare learning models with different assumptions about the amount of task-related information subjects may have inferred during the experiment. Here, we observed that the best-fitting model was a modified Rescorla-Wagner type model, the "double-update" model, which assumes that subjects infer the knowledge that reward contingencies are anti-correlated, and integrate both actual and hypothetical outcomes into their decisions. Moreover, comparison of the best-fitting model's parameters showed that ADP were less sensitive to punishments compared to HC. Hence, decisions of ADP after punishments were loosely coupled with the expected reward values assigned to them. A correlation analysis between the model-generated PEs and the fMRI data revealed a reduced association between these PEs and the BOLD activity in the dorsolateral prefrontal cortex (DLPFC) of ADP. A hemispheric asymmetry was observed in the DLPFC when positive and negative PE signals were analyzed separately. The right DLPFC activity in ADP showed a reduced correlation with positive PEs. On the other hand, ADP, particularly the patients with high dependence severity, recruited the left DLPFC to a lesser extent than HC for processing negative PE signals. These results suggest that the DLPFC, which has been linked to adaptive control of action selection, may play an important role in cognitive inflexibility observed in alcohol dependence when reinforcement contingencies change. Particularly, the left DLPFC may contribute to this impaired behavioral adaptation, possibly by impeding the extinction of the actions that no longer lead to a reward.}, language = {en} } @article{KaufmannMaiwaldSchindleretal.2017, author = {Kaufmann, Yvonne Marie and Maiwald, Lisa Marie and Schindler, Svenja and Weck, Florian}, title = {Wie wirkt sich mehrmaliges Kompetenz-Feedback auf psychotherapeutische Behandlungen aus?}, series = {Zeitschrift f{\"u}r klinische Psychologie und Psychotherapie : Forschung und Praxis}, volume = {46}, journal = {Zeitschrift f{\"u}r klinische Psychologie und Psychotherapie : Forschung und Praxis}, number = {2}, publisher = {Hogrefe}, address = {G{\"o}ttingen}, issn = {1616-3443}, doi = {10.1026/1616-3443/a000412}, pages = {96 -- 106}, year = {2017}, abstract = {Theoretischer Hintergrund: Einfl{\"u}sse von therapeutenorientiertem Kompetenz-Feedback in der Psychotherapieausbildung wurden bislang wenig untersucht. Fragestellung: Wie gehen Ausbildungstherapeuten mit Feedback um? Welchen Einfluss hat ein regelm{\"a}ßiges Kompetenz-Feedback auf die Qualit{\"a}t psychotherapeutischer Behandlungen (insbesondere Therapiesitzungen, therapeutische Beziehung, Person des Therapeuten, Supervision)? Methode: Elf Therapeuten wurden mithilfe eines halbstrukturierten Interviewleitfadens befragt. Die Auswertung erfolgte mittels qualitativer Inhaltsanalyse nach Mayring (2015). Ergebnisse: Das auf Basis der Interviews erstellte Kategoriensystem umfasste die Kategorien „Erwartungen an das Feedback", „Wahrnehmung des Feedbacks", „Verarbeitung von und Umgang mit Feedback", „Folgen, Auswirkungen und Ver{\"a}nderungen durch Feedback" sowie „Verbesserungsw{\"u}nsche". Schlussfolgerungen: Therapeuten streben eine Umsetzung des Feedbacks an, welches sich auf die Behandlung, die Supervision, die eigene Person und die therapeutische Beziehung auswirkt.}, language = {de} } @article{PengBehlZhangetal.2017, author = {Peng, Xingzhou and Behl, Marc and Zhang, Pengfei and Mazurek-Budzyńska, Magdalena and Feng, Yakai and Lendlein, Andreas}, title = {Synthesis and characterization of multiblock poly(ester-amide-urethane)s}, series = {MRS advances : a journal of the Materials Research Society (MRS)}, volume = {2}, journal = {MRS advances : a journal of the Materials Research Society (MRS)}, publisher = {Cambridge University Press}, address = {Cambridge}, issn = {2059-8521}, doi = {10.1557/adv.2017.486}, pages = {2551 -- 2559}, year = {2017}, abstract = {In this study, a multiblock copolymer containing oligo(3-methyl-morpholine-2, 5-dione) (oMMD) and oligo(3-sec-butyl-morpholine-2, 5-dione) (oBMD) building blocks obtained by ring-opening polymerization (ROP) of the corresponding monomers, was synthesized in a polyaddition reaction using an aliphatic diisocyanate. The multiblock copolymer (pBMD-MMD) provided a molecular weight of 40, 000 g·mol-1, determined by gel permeation chromatography (GPC). Incorporation of both oligodepsipeptide segments in multiblock copolymers was confirmed by 1H NMR and Matrix Assisted Laser Desorption/Ionization Time Of Flight Mass Spectroscopy (MALDI-TOF MS) analysis. pBMD-MMD showed two separated glass transition temperatures (61 °C and 74 °C) indicating a microphase separation. Furthermore, a broad glass transition was observed by DMTA, which can be attributed to strong physical interaction i.e. by H-bonds formed between amide, ester, and urethane groups of the investigated copolymers. The obtained multiblock copolymer is supposed to own the capability to exhibit strong physical interactions.}, language = {en} } @article{BuschhueterSpodenBorowski2017, author = {Buschh{\"u}ter, David and Spoden, Christian and Borowski, Andreas}, title = {Physics knowledge of first semester physics students in Germany}, series = {International journal of science education}, volume = {39}, journal = {International journal of science education}, number = {9}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {0950-0693}, doi = {10.1080/09500693.2017.1318457}, pages = {1109 -- 1132}, year = {2017}, abstract = {Over the last decades, the percentage of the age group choosing to pursue university studies has increased significantly across the world. At the same time, there are university teachers who believe that the standards have fallen. There is little research on whether students nowadays demonstrate knowledge or abilities similar to that of the preceding cohorts. However, in times of educational expansion, empirical evidence on student test performance is extremely helpful in evaluating how well educational systems cope with the increasing numbers of students. In this study, we compared a sample of 2322 physics freshmen from 2013 with another sample of 2718 physics freshmen from 1978 at universities in Germany with regard to their physics knowledge based on their results in the same entrance test. Previous results on mathematics knowledge and abilities in the same sample of students indicated that there was no severe decline in their average achievement. This paper compares the physics knowledge of the same two samples of students. Contrary to their mathematics results, their physics results showed a substantial decrease in physics knowledge as measured by the test.}, language = {en} } @article{Yılmaz2017, author = {Y{\i}lmaz, Zafer}, title = {The AKP and the spirit of the 'new' Turkey}, series = {Turkish studies}, volume = {18}, journal = {Turkish studies}, number = {3}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {1468-3849}, doi = {10.1080/14683849.2017.1314763}, pages = {482 -- 513}, year = {2017}, abstract = {A strong sense of victimhood, a discourse of social suffering, and complementary bodily performances, which mobilize rancor, resentfulness, and revengefulness, are fundamental elements of Turkish-Islamist ideology. This article discusses the political dynamics and implications of such assertions of victimhood in the Turkish context. To underscore these dynamics, it analyses the role of the logic of pain in the subject formation of Turkish-Islamist identity and how this logic has been revitalized by constitutive and hegemonic social imagination, and circulated and intensified by a reactionary mood. Additionally, it aims to expose how this reactionary mood profoundly depends on contradictory subjectification processes, which simultaneously involve mobilization of feelings of impotency, non-responsibility, self-pitying, and sublimation of power. This subject formation opens the way for identification with authoritarian figures in the Turkish case.}, language = {en} } @article{Muschalla2017, author = {Muschalla, Beate}, title = {Work-anxiety-coping intervention improves work-coping perception while a recreational intervention leads to deterioration}, series = {European journal of work and organizational psychology : the official journal of The European Association of Work and Organizational Psychology}, volume = {26}, journal = {European journal of work and organizational psychology : the official journal of The European Association of Work and Organizational Psychology}, number = {6}, publisher = {Taylor \& Francis}, address = {Abingdon}, issn = {1359-432X}, doi = {10.1080/1359432X.2017.1384378}, pages = {858 -- 869}, year = {2017}, abstract = {Work-anxieties are costly and need early intervention. The perception of being able to cope with work is a basic requirement for work ability. This randomized controlled trial investigates whether a cognitive behavioural, work-anxiety-coping group (WAG) intervention leads to better work-coping perception than an unspecific recreational group (RG). Heterogeneous people in medical rehabilitation, who were due to return to work, were interviewed concerning their work-anxieties, and either randomly assigned to a WAG (n=85) or a RG (n=95). The participants (with an average of 50years old [range 23-64]; 51\% women; 70\% workers or employees, 25\% academics, 5\% unskilled) followed the group intervention for four or six sessions. The perceived work-coping was assessed by self-rating (Inventory for Job-Coping and Return Intention JoCoRi) after each group session. Although participants had a slight temporary decrease in work-coping after group session two (from M-1=2.47 to M-2=2.28, d(Cohen)=-.22), the WAG led to the improvement of perceived work-coping over the intervention course (from M-1=2.47 to M-6=2.65, d(Cohen)=.18). In contrast, participants from the RG reported lower work-coping after six group sessions (from M-1=2.26 to M-6=2.02, d(Cohen)=-.18). It is considered that people with work-anxieties need training in work-coping. By focusing on recreation only, this may lead to deterioration of work-coping. Indeed, intervention designers should be aware of temporary deterioration (side effects) when confronting participants with work-coping.}, language = {en} } @article{Daviter2017, author = {Daviter, Falk}, title = {Coping, taming or solving}, series = {Policy studies}, volume = {38}, journal = {Policy studies}, number = {6}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {0144-2872}, doi = {10.1080/01442872.2017.1384543}, pages = {571 -- 588}, year = {2017}, abstract = {One of the truisms of policy analysis is that policy problems are rarely solved. As an ever-increasing number of policy issues are identified as an inherently ill-structured and intractable type of wicked problem, the question of what policy analysis sets out to accomplish has emerged as more central than ever. If solving wicked problems is beyond reach, research on wicked problems needs to provide a clearer understanding of the alternatives. The article identifies and explicates three distinguishable strategies of problem governance: coping, taming and solving. It shows that their intellectual premises and practical implications clearly contrast in core respects. The article argues that none of the identified strategies of problem governance is invariably more suitable for dealing with wicked problems. Rather than advocate for some universally applicable approach to the governance of wicked problems, the article asks under what conditions different ways of governing wicked problems are analytically reasonable and normatively justified. It concludes that a more systematic assessment of alternative approaches of problem governance requires a reorientation of the debate away from the conception of wicked problems as a singular type toward the more focused analysis of different dimensions of problem wickedness.}, language = {en} } @misc{KuehnSchoene2017, author = {K{\"u}hn, Michael and Sch{\"o}ne, Tim}, title = {Multivariate regression model from water level and production rate time series for the geothermal reservoir Waiwera (New Zealand)}, series = {Energy procedia}, volume = {125}, journal = {Energy procedia}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1876-6102}, doi = {10.1016/j.egypro.2017.08.196}, pages = {571 -- 579}, year = {2017}, abstract = {Water management tools are necessary to guarantee the preservation of natural resources while ensuring optimum utilization. Linear regression models are a simple and quick solution for creating prognostic capabilities. Multivariate models show higher precision than univariate models. In the case of Waiwera, implementation of individual production rates is more accurate than applying just the total production rate. A maximum of approximately 1,075 m3/day can be pumped to ensure a water level of at least 0.5 m a.s.l. in the monitoring well. The model should be renewed annually to implement new data and current water level trends to keep the quality.}, language = {en} } @misc{WetzelKempkaKuehn2017, author = {Wetzel, Maria and Kempka, Thomas and K{\"u}hn, Michael}, title = {Predicting macroscopic elastic rock properties requires detailed information on microstructure}, series = {Energy procedia}, volume = {125}, journal = {Energy procedia}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1876-6102}, doi = {10.1016/j.egypro.2017.08.195}, pages = {561 -- 570}, year = {2017}, abstract = {Predicting variations in macroscopic mechanical rock behaviour due to microstructural changes, driven by mineral precipitation and dissolution is necessary to couple chemo-mechanical processes in geological subsurface simulations. We apply 3D numerical homogenization models to estimate Young's moduli for five synthetic microstructures, and successfully validate our results for comparable geometries with the analytical Mori-Tanaka approach. Further, we demonstrate that considering specific rock microstructures is of paramount importance, since calculated elastic properties may deviate by up to 230 \% for the same mineral composition. Moreover, agreement between simulated and experimentally determined Young's moduli is significantly improved, when detailed spatial information are employed.}, language = {en} } @misc{KuehnLiNakatenetal.2017, author = {K{\"u}hn, Michael and Li, Qi and Nakaten, Natalie Christine and Kempka, Thomas}, title = {Integrated subsurface gas storage of CO2 and CH4 offers capacity and state-of-the-art technology for energy storage in China}, series = {Energy procedia}, volume = {125}, journal = {Energy procedia}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1876-6102}, doi = {10.1016/j.egypro.2017.08.039}, pages = {14 -- 18}, year = {2017}, abstract = {Integration and development of the energy supply in China and worldwide is a challenge for the years to come. The innovative idea presented here is based on an extension of the "power-to-gas-to-power" technology by establishing a closed carbon cycle. It is an implementation of a low-carbon energy system based on carbon dioxide capture and storage (CCS) to store and reuse wind and solar energy. The Chenjiacun storage project in China compares well with the German case study for the towns Potsdam and Brandenburg/Havel in the Federal State of Brandenburg based on the Ketzin pilot site for CCS.}, language = {en} } @misc{KuehnKempkadeLuciaetal.2017, author = {K{\"u}hn, Michael and Kempka, Thomas and de Lucia, Marco and Scheck-Wenderoth, Magdalena}, title = {Dissolved CO2 storage in geological formations with low pressure, low risk and large capacities}, series = {Energy procedia}, volume = {114}, journal = {Energy procedia}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1876-6102}, doi = {10.1016/j.egypro.2017.03.1607}, pages = {4722 -- 4727}, year = {2017}, abstract = {Geological CO2 storage is a mitigation technology to reduce CO2 emissions from fossil fuel combustion. However, major concerns are the pressure increase and saltwater displacement in the mainly targeted deep groundwater aquifers due to injection of supercritical CO2. The suggested solution is storage of CO2 exclusively in the dissolved state. In our exemplary regional case study of the North East German Basin based on a highly resolved temperature and pressure distribution model and a newly developed reactive transport coupling, we have quantified that 4.7 Gt of CO2 can be stored in solution compared to 1.5 Gt in the supercritical state.}, language = {en} } @article{PyšekPerglEssletal.2017, author = {Pyšek, Petr and Pergl, Jan and Essl, Franz and Lenzner, Bernd and Dawson, Wayne and Kreft, Holger and Weigelt, Patrick and Winter, Marten and Kartesz, John and Nishino, Misako and Antonova, Liubov A. and Barcelona, Julie F. and Cabezas, Francisco Jos{\´e} and C{\´a}rdenas L{\´o}pez, Dairon and C{\´a}rdenas-Toro, Juliana and Castańo, Nicol{\´a}s and Chac{\´o}n, Eduardo and Chatelain, Cyrille and Dullinger, Stefan and Ebel, Aleksandr L. and Figueiredo, Estrela and Fuentes, Nicol and Genovesi, Piero and Groom, Quentin J. and Henderson, Lesley and Inderjit, and Kupriyanov, Andrey and Masciadri, Silvana and Maurel, No{\"e}lie and Meerman, Jan and Morozova, Olʹga V. and Moser, Dietmar and Nickrent, Daniel and Nowak, Pauline M. and Pagad, Shyama and Patzelt, Annette and Pelser, Pieter B. and Seebens, Hanno and Shu, Wen-sheng and Thomas, Jacob and Velayos, Mauricio and Weber, Ewald and Wieringa, Jan J. and Baptiste, Maria P. and Kleunen, Mark van}, title = {Naturalized alien flora of the world}, series = {Preslia : the journal of the Czech Botanical Society}, volume = {89}, journal = {Preslia : the journal of the Czech Botanical Society}, number = {3}, publisher = {Czech Botanical Soc.}, address = {Praha}, issn = {0032-7786}, doi = {10.23855/preslia.2017.203}, pages = {203 -- 274}, year = {2017}, abstract = {Using the recently built Global Naturalized Alien Flora (GloNAF) database, containing data on the distribution of naturalized alien plants in 483 mainland and 361 island regions of the world, we describe patterns in diversity and geographic distribution of naturalized and invasive plant species, taxonomic, phylogenetic and life-history structure of the global naturalized flora as well as levels of naturalization and their determinants. The mainland regions with the highest numbers of naturalized aliens are some Australian states (with New South Wales being the richest on this continent) and several North American regions (of which California with 1753 naturalized plant species represents the world’s richest region in terms of naturalized alien vascular plants). England, Japan, New Zealand and the Hawaiian archipelago harbour most naturalized plants among islands or island groups. These regions also form the main hotspots of the regional levels of naturalization, measured as the percentage of naturalized aliens in the total flora of the region. Such hotspots of relative naturalized species richness appear on both the western and eastern coasts of North America, in north-western Europe, South Africa, south-eastern Australia, New Zealand, and India. High levels of island invasions by naturalized plants are concentrated in the Pacific, but also occur on individual islands across all oceans. The numbers of naturalized species are closely correlated with those of native species, with a stronger correlation and steeper increase for islands than mainland regions, indicating a greater vulnerability of islands to invasion by species that become successfully naturalized. South Africa, India, California, Cuba, Florida, Queensland and Japan have the highest numbers of invasive species. Regions in temperate and tropical zonobiomes harbour in total 9036 and 6774 naturalized species, respectively, followed by 3280 species naturalized in the Mediterranean zonobiome, 3057 in the subtropical zonobiome and 321 in the Arctic. The New World is richer in naturalized alien plants, with 9905 species compared to 7923 recorded in the Old World. While isolation is the key factor driving the level of naturalization on islands, zonobiomes differing in climatic regimes, and socioeconomy represented by per capita GDP, are central for mainland regions. The 11 most widely distributed species each occur in regions covering about one third of the globe or more in terms of the number of regions where they are naturalized and at least 35\% of the Earth’s land surface in terms of those regions’ areas, with the most widely distributed species Sonchus oleraceus occuring in 48\% of the regions that cover 42\% of the world area. Other widely distributed species are Ricinus communis, Oxalis corniculata, Portulaca oleracea, Eleusine indica, Chenopodium album, Capsella bursa-pastoris, Stellaria media, Bidens pilosa, Datura stramonium and Echinochloa crus-galli. Using the occurrence as invasive rather than only naturalized yields a different ranking, with Lantana camara (120 regions out of 349 for which data on invasive status are known), Calotropis procera (118), Eichhornia crassipes (113), Sonchus oleraceus (108) and Leucaena leucocephala (103) on top. As to the life-history spectra, islands harbour more naturalized woody species (34.4\%) thanmainland regions (29.5\%), and fewer annual herbs (18.7\% compared to 22.3\%). Ranking families by their absolute numbers of naturalized species reveals that Compositae (1343 species), Poaceae (1267) and Leguminosae (1189) contribute most to the global naturalized alien flora. Some families are disproportionally represented by naturalized aliens on islands (Arecaceae, Araceae, Acanthaceae, Amaryllidaceae, Asparagaceae, Convolvulaceae, Rubiaceae, Malvaceae), and much fewer so on mainland (e.g. Brassicaceae, Caryophyllaceae, Boraginaceae). Relating the numbers of naturalized species in a family to its total global richness shows that some of the large species-rich families are over-represented among naturalized aliens (e.g. Poaceae, Leguminosae, Rosaceae, Amaranthaceae, Pinaceae), some under-represented (e.g. Euphorbiaceae, Rubiaceae), whereas the one richest in naturalized species, Compositae, reaches a value expected from its global species richness. Significant phylogenetic signal indicates that families with an increased potential of their species to naturalize are not distributed randomly on the evolutionary tree. Solanum (112 species), Euphorbia (108) and Carex (106) are the genera richest in terms of naturalized species; over-represented on islands are Cotoneaster, Juncus, Eucalyptus, Salix, Hypericum, Geranium and Persicaria, while those relatively richer in naturalized species on the mainland are Atriplex, Opuntia, Oenothera, Artemisia, Vicia, Galium and Rosa. The data presented in this paper also point to where information is lacking and set priorities for future data collection. The GloNAF database has potential for designing concerted action to fill such data gaps, and provide a basis for allocating resources most efficiently towards better understanding and management of plant invasions worldwide.}, language = {en} } @misc{PlauthSterzEberhardtetal.2017, author = {Plauth, Max and Sterz, Christoph and Eberhardt, Felix and Feinbube, Frank and Polze, Andreas}, title = {Assessing NUMA performance based on hardware event counters}, series = {IEEE International Parallel and Distributed Processing Symposium Workshops (IPDPSW)}, journal = {IEEE International Parallel and Distributed Processing Symposium Workshops (IPDPSW)}, publisher = {Institute of Electrical and Electronics Engineers}, address = {New York}, isbn = {978-0-7695-6149-3}, issn = {2164-7062}, doi = {10.1109/IPDPSW.2017.51}, pages = {904 -- 913}, year = {2017}, abstract = {Cost models play an important role for the efficient implementation of software systems. These models can be embedded in operating systems and execution environments to optimize execution at run time. Even though non-uniform memory access (NUMA) architectures are dominating today's server landscape, there is still a lack of parallel cost models that represent NUMA system sufficiently. Therefore, the existing NUMA models are analyzed, and a two-step performance assessment strategy is proposed that incorporates low-level hardware counters as performance indicators. To support the two-step strategy, multiple tools are developed, all accumulating and enriching specific hardware event counter information, to explore, measure, and visualize these low-overhead performance indicators. The tools are showcased and discussed alongside specific experiments in the realm of performance assessment.}, language = {en} } @misc{TorkuraSukmanaChengetal.2017, author = {Torkura, Kennedy A. and Sukmana, Muhammad Ihsan Haikal and Cheng, Feng and Meinel, Christoph}, title = {Leveraging cloud native design patterns for security-as-a-service applications}, series = {IEEE International Conference on Smart Cloud (SmartCloud)}, journal = {IEEE International Conference on Smart Cloud (SmartCloud)}, publisher = {Institute of Electrical and Electronics Engineers}, address = {New York}, isbn = {978-1-5386-3684-8}, doi = {10.1109/SmartCloud.2017.21}, pages = {90 -- 97}, year = {2017}, abstract = {This paper discusses a new approach for designing and deploying Security-as-a-Service (SecaaS) applications using cloud native design patterns. Current SecaaS approaches do not efficiently handle the increasing threats to computer systems and applications. For example, requests for security assessments drastically increase after a high-risk security vulnerability is disclosed. In such scenarios, SecaaS applications are unable to dynamically scale to serve requests. A root cause of this challenge is employment of architectures not specifically fitted to cloud environments. Cloud native design patterns resolve this challenge by enabling certain properties e.g. massive scalability and resiliency via the combination of microservice patterns and cloud-focused design patterns. However adopting these patterns is a complex process, during which several security issues are introduced. In this work, we investigate these security issues, we redesign and deploy a monolithic SecaaS application using cloud native design patterns while considering appropriate, layered security counter-measures i.e. at the application and cloud networking layer. Our prototype implementation out-performs traditional, monolithic applications with an average Scanner Time of 6 minutes, without compromising security. Our approach can be employed for designing secure, scalable and performant SecaaS applications that effectively handle unexpected increase in security assessment requests.}, language = {en} } @article{Ette2017, author = {Ette, Ottmar}, title = {Welterleben/Weiterleben}, series = {Daphnis : Zeitschrift f{\"u}r mittlere deutsche Literatur}, volume = {45}, journal = {Daphnis : Zeitschrift f{\"u}r mittlere deutsche Literatur}, number = {3-4}, publisher = {Editions Rodopi BV}, address = {Amsterdam}, issn = {0300-693X}, doi = {10.1163/18796583-04503002}, pages = {343 -- 388}, year = {2017}, abstract = {Welterleben and Weiterleben are what determine the second globalization (of four previously explored) whose constantly accelerating dynamic, vectorization, this essay explores. On the basis of selected writings of Georg Forster, Alexander von Humboldt, and Adelbert von Chamisso, the author highlights the increasing speed with which knowledge, especially in the experiential sciences, is produced and disseminated following the routes of ever-widening trade speeded along by globalization. The notion of 'vectopia' stands for the connection of utopia and uchronia in space and time in such a way that the experience of the world, expanded worldwide, contains within it a Weiter-Leben, a 'living-further' that is to be understood first in a spatial, and not yet temporal, sense, of what Forster called Erfahrungswissen, or 'experiential knowledge.' Vectopia, as elaborated here, has a material dimension that relates to the physical person, the body, the experience of the world that cannot occur without the constant changing of place, without a journeying that is again and again recommenced. Vectopia develops the projection of a life not from space or from time alone, but by their combination. Vectopia is more than a concept, it is a thought-figure: it is vitally connected to life, and thus a life-figure. It opens itself to a type of knowledge that stands almost at the threshold of a further life, indeed, of a Weiterleben that, opening itself to a 'living-onward,' resides beyond space, time, and movement.}, language = {en} } @misc{LimbergerScheibelTrappetal.2017, author = {Limberger, Daniel and Scheibel, Willy and Trapp, Matthias and D{\"o}llner, J{\"u}rgen Roland Friedrich}, title = {Mixed-projection treemaps}, series = {21st International Conference Information Visualisation (IV)}, journal = {21st International Conference Information Visualisation (IV)}, publisher = {Institute of Electrical and Electronics Engineers}, address = {Los Alamitos}, isbn = {978-1-5386-0831-9}, issn = {2375-0138}, doi = {10.1109/iV.2017.67}, pages = {164 -- 169}, year = {2017}, abstract = {This paper presents a novel technique for combining 2D and 2.5D treemaps using multi-perspective views to leverage the advantages of both treemap types. It enables a new form of overview+detail visualization for tree-structured data and contributes new concepts for real-time rendering of and interaction with treemaps. The technique operates by tilting the graphical elements representing inner nodes using affine transformations and animated state transitions. We explain how to mix orthogonal and perspective projections within a single treemap. Finally, we show application examples that benefit from the reduced interaction overhead.}, language = {en} } @misc{SaintDizierStede2017, author = {Saint-Dizier, Patrick and Stede, Manfred}, title = {Foundations of the language of argumentation}, series = {Argument \& computation}, volume = {8}, journal = {Argument \& computation}, number = {2 Special issue}, publisher = {IOS Press}, address = {Amsterdam}, issn = {1946-2166}, doi = {10.3233/AAC-170018}, pages = {91 -- 93}, year = {2017}, language = {en} } @misc{WaldripNivenAbeletal.2017, author = {Waldrip, Steven H. and Niven, Robert K. and Abel, Markus and Schlegel, Michael}, title = {Consistent maximum entropy representations of pipe flow networks}, series = {AIP conference proceedings}, volume = {1853}, journal = {AIP conference proceedings}, number = {1}, publisher = {American Institute of Physics}, address = {Melville}, isbn = {978-0-7354-1527-0}, issn = {0094-243X}, doi = {10.1063/1.4985365}, year = {2017}, abstract = {The maximum entropy method is used to predict flows on water distribution networks. This analysis extends the water distribution network formulation of Waldrip et al. (2016) Journal of Hydraulic Engineering (ASCE), by the use of a continuous relative entropy defined on a reduced parameter set. This reduction in the parameters that the entropy is defined over ensures consistency between different representations of the same network. The performance of the proposed reduced parameter method is demonstrated with a one-loop network case study.}, language = {en} } @misc{WaldripNivenAbeletal.2017, author = {Waldrip, Steven H. and Niven, Robert K. and Abel, Markus and Schlegel, Michael}, title = {Maximum entropy analysis of transport networks}, series = {AIP conference proceedings}, volume = {1853}, journal = {AIP conference proceedings}, number = {1}, publisher = {American Institute of Physics}, address = {Melville}, isbn = {978-0-7354-1527-0}, issn = {0094-243X}, doi = {10.1063/1.4985364}, pages = {8}, year = {2017}, abstract = {The maximum entropy method is used to derive an alternative gravity model for a transport network. The proposed method builds on previous methods which assign the discrete value of a maximum entropy distribution to equal the traffic flow rate. The proposed method however, uses a distribution to represent each flow rate. The proposed method is shown to be able to handle uncertainty in a more elegant way and give similar results to traditional methods. It is able to incorporate more of the observed data through the entropy function, prior distribution and integration limits potentially allowing better inferences to be made.}, language = {en} } @article{HartigPirro2017, author = {Hartig, Olaf and Pirr{\`o}, Giuseppe}, title = {SPARQL with property paths on the Web}, series = {Semantic web}, volume = {8}, journal = {Semantic web}, number = {6}, publisher = {IOS Press}, address = {Amsterdam}, issn = {1570-0844}, doi = {10.3233/SW-160237}, pages = {773 -- 795}, year = {2017}, abstract = {Linked Data on the Web represents an immense source of knowledge suitable to be automatically processed and queried. In this respect, there are different approaches for Linked Data querying that differ on the degree of centralization adopted. On one hand, the SPARQL query language, originally defined for querying single datasets, has been enhanced with features to query federations of datasets; however, this attempt is not sufficient to cope with the distributed nature of data sources available as Linked Data. On the other hand, extensions or variations of SPARQL aim to find trade-offs between centralized and fully distributed querying. The idea is to partially move the computational load from the servers to the clients. Despite the variety and the relative merits of these approaches, as of today, there is no standard language for querying Linked Data on theWeb. A specific requirement for such a language to capture the distributed, graph-like nature of Linked Data sources on the Web is a support of graph navigation. Recently, SPARQL has been extended with a navigational feature called property paths (PPs). However, the semantics of SPARQL restricts the scope of navigation via PPs to single RDF graphs. This restriction limits the applicability of PPs for querying distributed Linked Data sources on the Web. To fill this gap, in this paper we provide formal foundations for evaluating PPs on the Web, thus contributing to the definition of a query language for Linked Data. We first introduce a family of reachability-based query semantics for PPs that distinguish between navigation on the Web and navigation at the data level. Thereafter, we consider another, alternative query semantics that couples Web graph navigation and data level navigation; we call it context-based semantics. Given these semantics, we find that for some PP-based SPARQL queries a complete evaluation on the Web is not possible. To study this phenomenon we introduce a notion of Web-safeness of queries, and prove a decidable syntactic property that enables systems to identify queries that areWeb-safe. In addition to establishing these formal foundations, we conducted an experimental comparison of the context-based semantics and a reachability- based semantics. Our experiments show that when evaluating a PP-based query under the context-based semantics one experiences a significantly smaller number of dereferencing operations, but the computed query result may contain less solutions.}, language = {en} } @incollection{Kuegler2017, author = {K{\"u}gler, Frank}, title = {Tone and intonation in Akan}, series = {Intonation in African Tone Languages}, volume = {24}, booktitle = {Intonation in African Tone Languages}, publisher = {De Gruyter Mouton}, address = {Berlin}, isbn = {978-3-11-050352-4; 978-3-11-048479-3}, issn = {1861-4191}, doi = {10.1515/9783110503524-004}, pages = {89 -- 129}, year = {2017}, abstract = {This chapter provides an account of the intonation patterns in Akan (Kwa, Niger-Congo). Tonal processes such as downstep, tonal spreading and tonal replacement influence the surface tone pattern of a sentence. In general, any Akan utterance independent of sentence type shows a characteristic down-trend in pitch. This chapter proposes that Akan employs a simple post-lexical tonal grammar that accounts for the shapes of an intonation contour. The unmarked post-lexical structure is found in simple declaratives. The downward trend of an intonation contour is shaped by local tonal interactions (downstep), and sentence-final tonal neutralization. In polar questions, an iota-phrase-final low boundary tone (L\%) accounts for the intensity increase and lengthening of the final vowel compared to a declarative. Complex declaratives and left-dislocations show a partial pitch reset at the left edge of an embedded iota-phrase. Underlying lexical tones are not affected by intonation with the exception of sentence-final H-tones.}, language = {en} } @misc{GronauUllrichTeichmann2017, author = {Gronau, Norbert and Ullrich, Andr{\´e} and Teichmann, Malte}, title = {Development of the industrial IoT competences in the areas of organization, process, and interaction based on the learning factory concept}, series = {Procedia manufacturing}, volume = {9}, journal = {Procedia manufacturing}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2351-9789}, doi = {10.1016/j.promfg.2017.04.029}, pages = {254 -- 261}, year = {2017}, abstract = {Lately, first implementation approaches of Internet of Things (IoT) technologies penetrate industrial value-adding processes. Within this, the competence requirements for employees are changing. Employees' organization, process, and interaction competences are of crucial importance in this new IoT environment, however, in students and vocational training not sufficiently considered yet. On the other hand, conventional learning factories evolve and transform to digital learning factories. Nevertheless, the integration of IoT technology and its usage for training in digital learning factories has been largely neglected thus far. Existing learning factories do not explicitly and properly consider IoT technology, which leads to deficiencies regarding an appropriate development of employees' Industrial IoT competences. The goal of this contribution is to point out a didactic concept that enables development and training of these new demanded competences by using an IoT laboratory. For this purpose, a design science approach is applied. The result of this contribution is a didactic concept for the development of Industrial IoT competences in an IoT laboratory.}, language = {en} } @article{ParamonovKuehnBandrauk2017, author = {Paramonov, Guennaddi K. and K{\"u}hn, Oliver and Bandrauk, Andr{\´e} D.}, title = {Excitation of H+ 2 with one-cycle laser pulses}, series = {Molecular physics : MP ; an international journal in the field of chemical physics}, volume = {115}, journal = {Molecular physics : MP ; an international journal in the field of chemical physics}, number = {15/16}, publisher = {Taylor \& Francis}, address = {London}, issn = {0026-8976}, doi = {10.1080/00268976.2017.1288938}, pages = {1846 -- 1860}, year = {2017}, abstract = {Non-Born-Oppenheimer quantum dynamics of H+ 2 excited by shaped one-cycle laser pulses linearly polarised along the molecular axis have been studied by the numerical solution of the time-dependent Schr{\"o}dinger equation within a three-dimensional model, including the internuclear separation, R, and the electron coordinates z and ρ. Laser carrier frequencies corresponding to the wavelengths λ l = 25 nm through λ l = 400 nm were used and the amplitudes of the pulses were chosen such that the energy of H+ 2 was close to its dissociation threshold at the end of any laser pulse applied. It is shown that there exists a characteristic oscillation frequency ωosc ≃ 0.2265 au (corresponding to the period of τosc ≃ 0.671 fs and the wavelength of λosc ≃ 201 nm) that manifests itself as a 'carrier' frequency of temporally shaped oscillations of the time-dependent expectation values ⟨z ⟩ and ⟨∂V/∂z ⟩ that emerge at the ends of the laser pulses and exist on a timescale of at least 50 fs. Time-dependent expectation values ⟨ρ⟩ and ⟨∂V /∂ρ⟩ of the optically passive degree of freedom, ρ, demonstrate post-laser-field oscillations at two basic frequencies ωρ 1 ≈ ωosc and ωρ 2 ≈ 2ωosc. Power spectra associated with the electronic motion show higher- and lower-order harmonics with respect to the driving field.}, language = {en} } @article{WiemersBekkeringLindemann2017, author = {Wiemers, Michael and Bekkering, Harold and Lindemann, Oliver}, title = {Is more always up?}, series = {Journal of cognitive psychology}, volume = {29}, journal = {Journal of cognitive psychology}, number = {5}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {2044-5911}, doi = {10.1080/20445911.2017.1302451}, pages = {642 -- 652}, year = {2017}, abstract = {It has been argued that the association of numbers and vertical space plays a fundamental role for the understanding of numerical concepts. However, convincing evidence for an association of numbers and vertical bimanual responses is still lacking. The present study tests the vertical Spatio-Numerical-Association-of-Response-Codes (SNARC) effect in a number classification task by comparing anatomical hand-based and spatial associations. A mixed effects model of linear spatial-numerical associations revealed no evidence for a vertical but clear support for an anatomical SNARC effect. Only if the task requirements prevented participants from using a number-hand association due to frequently alternating hand-to-button assignments, numbers were associated with the vertical dimension. Taken together, the present findings question the importance of vertical associations for the conceptual understanding of numerical magnitude as hypothesised by some embodied approaches to number cognition and suggest a preference for ego-over geocentric reference frames for the mapping of numbers onto space.}, language = {en} } @article{Richter2017, author = {Richter, Philipp}, title = {Gas accretion onto the Milky Way}, series = {Astrophysics and space science library}, volume = {430}, journal = {Astrophysics and space science library}, editor = {Fox, Andrew J. and Dav{\´e}, Romeel}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-52512-9}, issn = {0067-0057}, doi = {10.1007/978-3-319-52512-9_2}, pages = {15 -- 47}, year = {2017}, abstract = {The Milky Way is surrounded by large amounts of gaseous matter that are slowly being accreted over cosmic timescales to support star formation in the disk. The corresponding gas-accretion rate represents a key parameter for the past, present, and future evolution of the Milky Way. In this chapter, we discuss our current understanding of gas accretion processes in the Galaxy by reviewing past and recent observational and theoretical studies. The first part of this review deals with the spatial distribution of the different gas phases in the Milky Way halo, the origin of the gas, and its total mass. The second part discusses the gas dynamics and the physical processes that regulate the gas flow from the outer Galactic halo to the disk. From the most recent studies follows that the present-day gas accretion rate of the Milky Way is a few solar masses per year, which is sufficient to maintain the Galaxy's star-formation rate at its current level.}, language = {en} } @misc{Kay2017, author = {Kay, Alex James}, title = {Disagreement is fine. Misrepresentation is not}, series = {The international history review}, volume = {39}, journal = {The international history review}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {0707-5332}, doi = {10.1080/07075332.2017.1354547}, pages = {929 -- 930}, year = {2017}, language = {en} } @misc{Giese2017, author = {Giese, Holger}, title = {Formal models and analysis for self-adaptive cyber-physical systems}, series = {Lecture notes in computer science}, volume = {10231}, journal = {Lecture notes in computer science}, editor = {Kouchnarenko, Olga and Khosravi, Ramtin}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-57666-4}, issn = {0302-9743}, doi = {10.1007/978-3-319-57666-4_1}, pages = {3 -- 9}, year = {2017}, abstract = {In this extended abstract, we will analyze the current challenges for the envisioned Self-Adaptive CPS. In addition, we will outline our results to approach these challenges with SMARTSOS [10] a generic approach based on extensions of graph transformation systems employing open and adaptive collaborations and models at runtime for trustworthy self-adaptation, self-organization, and evolution of the individual systems and the system-of-systems level taking the independent development, operation, management, and evolution of these systems into account.}, language = {en} } @misc{SerthPodlesnyBornsteinetal.2017, author = {Serth, Sebastian and Podlesny, Nikolai and Bornstein, Marvin and Lindemann, Jan and Latt, Johanna and Selke, Jan and Schlosser, Rainer and Boissier, Martin and Uflacker, Matthias}, title = {An interactive platform to simulate dynamic pricing competition on online marketplaces}, series = {2017 IEEE 21st International Enterprise Distributed Object Computing Conference (EDOC)}, journal = {2017 IEEE 21st International Enterprise Distributed Object Computing Conference (EDOC)}, publisher = {Institute of Electrical and Electronics Engineers}, address = {New York}, isbn = {978-1-5090-3045-3}, issn = {2325-6354}, doi = {10.1109/EDOC.2017.17}, pages = {61 -- 66}, year = {2017}, abstract = {E-commerce marketplaces are highly dynamic with constant competition. While this competition is challenging for many merchants, it also provides plenty of opportunities, e.g., by allowing them to automatically adjust prices in order to react to changing market situations. For practitioners however, testing automated pricing strategies is time-consuming and potentially hazardously when done in production. Researchers, on the other side, struggle to study how pricing strategies interact under heavy competition. As a consequence, we built an open continuous time framework to simulate dynamic pricing competition called Price Wars. The microservice-based architecture provides a scalable platform for large competitions with dozens of merchants and a large random stream of consumers. Our platform stores each event in a distributed log. This allows to provide different performance measures enabling users to compare profit and revenue of various repricing strategies in real-time. For researchers, price trajectories are shown which ease evaluating mutual price reactions of competing strategies. Furthermore, merchants can access historical marketplace data and apply machine learning. By providing a set of customizable, artificial merchants, users can easily simulate both simple rule-based strategies as well as sophisticated data-driven strategies using demand learning to optimize their pricing strategies.}, language = {en} } @article{SeiffertHolsteinSchlosseretal.2017, author = {Seiffert, Martin and Holstein, Flavio and Schlosser, Rainer and Schiller, Jochen}, title = {Next generation cooperative wearables}, series = {IEEE access : practical research, open solutions}, volume = {5}, journal = {IEEE access : practical research, open solutions}, publisher = {Institute of Electrical and Electronics Engineers}, address = {Piscataway}, issn = {2169-3536}, doi = {10.1109/ACCESS.2017.2749005}, pages = {16793 -- 16807}, year = {2017}, abstract = {Currently available wearables are usually based on a single sensor node with integrated capabilities for classifying different activities. The next generation of cooperative wearables could be able to identify not only activities, but also to evaluate them qualitatively using the data of several sensor nodes attached to the body, to provide detailed feedback for the improvement of the execution. Especially within the application domains of sports and health-care, such immediate feedback to the execution of body movements is crucial for (re-) learning and improving motor skills. To enable such systems for a broad range of activities, generalized approaches for human motion assessment within sensor networks are required. In this paper, we present a generalized trainable activity assessment chain (AAC) for the online assessment of periodic human activity within a wireless body area network. AAC evaluates the execution of separate movements of a prior trained activity on a fine-grained quality scale. We connect qualitative assessment with human knowledge by projecting the AAC on the hierarchical decomposition of motion performed by the human body as well as establishing the assessment on a kinematic evaluation of biomechanically distinct motion fragments. We evaluate AAC in a real-world setting and show that AAC successfully delimits the movements of correctly performed activity from faulty executions and provides detailed reasons for the activity assessment.}, language = {en} } @misc{LowHentschelStoberetal.2017, author = {Low, Thomas and Hentschel, Christian and Stober, Sebastian and Sack, Harald and N{\"u}rnberger, Andreas}, title = {Exploring large movie collections}, series = {Lecture notes in computer science}, volume = {10133}, journal = {Lecture notes in computer science}, editor = {Amsaleg, Laurent and Guðmundsson, Gylfi Þ{\´o}r and Gurrin, Cathal and J{\´o}nsson, Bj{\"o}rn Þ{\´o}r and Satoh, Shin'ichi}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-51814-5}, issn = {0302-9743}, doi = {10.1007/978-3-319-51814-5_17}, pages = {198 -- 208}, year = {2017}, abstract = {We compare Visual Berrypicking, an interactive approach allowing users to explore large and highly faceted information spaces using similarity-based two-dimensional maps, with traditional browsing techniques. For large datasets, current projection methods used to generate maplike overviews suffer from increased computational costs and a loss of accuracy resulting in inconsistent visualizations. We propose to interactively align inexpensive small maps, showing local neighborhoods only, which ideally creates the impression of panning a large map. For evaluation, we designed a web-based prototype for movie exploration and compared it to the web interface of The Movie Database (TMDb) in an online user study. Results suggest that users are able to effectively explore large movie collections by hopping from one neighborhood to the next. Additionally, due to the projection of movie similarities, interesting links between movies can be found more easily, and thus, compared to browsing serendipitous discoveries are more likely.}, language = {en} } @article{WieczorekKolmogorovKruseetal.2017, author = {Wieczorek, Mareike and Kolmogorov, Alexei and Kruse, Stefan and Jacobsen, Inga and Nitze, Ingmar and Nikolaev, Anatoly N. and Heinrich, Ingo and Pestryakova, Luidmila Agafyevna and Herzschuh, Ulrike}, title = {Disturbance-effects on treeline larch-stands in the lower Kolyma River area (NE Siberia)}, series = {Silva Fennica : a quarterly journal for forest science}, volume = {51}, journal = {Silva Fennica : a quarterly journal for forest science}, number = {3}, publisher = {The Finnish Society of Forest Science}, address = {Helsinki}, issn = {0037-5330}, doi = {10.14214/sf.1666}, pages = {20}, year = {2017}, abstract = {Tree stands in the boreal treeline ecotone are, in addition to climate change, impacted by disturbances such as fire, water-related disturbances and logging. We aim to understand how these disturbances affect growth, age structure, and spatial patterns of larch stands in the north-eastern Siberian treeline ecotone (lower Kolyma River region), an insufficiently researched region. Stand structure of Larix cajanderi Mayr was studied at seven sites impacted by disturbances. Maximum tree age ranged from 44 to 300 years. Young to medium-aged stands had, independent of disturbance type, the highest stand densities with over 4000 larch trees per ha. These sites also had the highest growth rates for tree height and stem diameter. Overall lowest stand densities were found in a polygonal field at the northern end of the study area, with larches growing in distinct " tree islands". At all sites, saplings are significantly clustered. Differences in fire severity led to contrasting stand structures with respect to tree, recruit, and overall stand densities. While a low severity fire resulted in low-density stands with high proportions of small and young larches, high severity fires resulted in high-density stands with high proportions of big trees. At waterdisturbed sites, stand structure varied between waterlogged and drained sites and latitude. These mixed effects of climate and disturbance make it difficult to predict future stand characteristics and the treeline position.}, language = {en} } @misc{FraschettiPohl2017, author = {Fraschetti, Federico and Pohl, Martin}, title = {Two-zone model for the broadband crab nebula spectrum}, series = {The European physical journal : Web of Conferences : proceedings}, volume = {136}, journal = {The European physical journal : Web of Conferences : proceedings}, publisher = {EDP Sciences}, address = {Les Ulis}, issn = {2100-014X}, doi = {10.1051/epjconf/201713602009}, pages = {5}, year = {2017}, abstract = {We develop a simple two-zone interpretation of the broadband baseline Crab nebula spectrum between 10(-5) eV and similar to 100 TeV by using two distinct log-parabola energetic electrons distributions. We determine analytically the very-high energy photon spectrum as originated by inverse-Compton scattering of the far-infrared soft ambient photons within the nebula off a first population of electrons energized at the nebula termination shock. The broad and flat 200 GeV peak jointly observed by Fermi/LAT and MAGIC is naturally reproduced. The synchrotron radiation from a second energetic electron population explains the spectrum from the radio range up to similar to 10 keV. We infer from observations the energy dependence of the microscopic probability of remaining in proximity of the shock of the accelerating electrons.}, language = {en} } @article{HoehnJerniganJaptoketal.2017, author = {Hoehn, Richard S. and Jernigan, Peter L. and Japtok, Lukasz and Chang, Alex L. and Midura, Emily F. and Caldwell, Charles C. and Kleuser, Burkhard and Lentsch, Alex B. and Edwards, Michael J. and Gulbins, Erich and Pritts, Timothy A.}, title = {Acid sphingomyelinase inhibition in stored erythrocytes reduces transfusion-associated lung inflammation}, series = {Annals of surgery : a monthly review of surgical science and practice}, volume = {265}, journal = {Annals of surgery : a monthly review of surgical science and practice}, number = {1}, publisher = {Lippincott Williams \& Wilkins}, address = {Philadelphia}, issn = {0003-4932}, doi = {10.1097/SLA.0000000000001648}, pages = {218 -- 226}, year = {2017}, abstract = {Objective: We aimed to identify the role of the enzyme acid sphingomyelinase in the aging of stored units of packed red blood cells (pRBCs) and subsequent lung inflammation after transfusion. Summary Background Data: Large volume pRBC transfusions are associated with multiple adverse clinical sequelae, including lung inflammation. Microparticles are formed in stored pRBCs over time and have been shown to contribute to lung inflammation after transfusion. Methods: Human and murine pRBCs were stored with or without amitriptyline, a functional inhibitor of acid sphingomyelinase, or obtained from acid sphingomyelinase-deficient mice, and lung inflammation was studied in mice receiving transfusions of pRBCs and microparticles isolated from these units. Results: Acid sphingomyelinase activity in pRBCs was associated with the formation of ceramide and the release of microparticles. Treatment of pRBCs with amitriptyline inhibited acid sphingomyelinase activity, ceramide accumulation, and microparticle production during pRBC storage. Transfusion of aged pRBCs or microparticles isolated from aged blood into mice caused lung inflammation. This was attenuated after transfusion of pRBCs treated with amitriptyline or from acid sphingomyelinase-deficient mice. Conclusions: Acid sphingomyelinase inhibition in stored pRBCs offers a novel mechanism for improving the quality of stored blood.}, language = {en} } @misc{YangDarkoHuangetal.2017, author = {Yang, Xiaoping and Darko, Kwame Oteng and Huang, Yanjun and He, Caimei and Yang, Huansheng and He, Shanping and Li, Jianzhong and Li, Jian and Hocher, Berthold and Yin, Yulong}, title = {Resistant starch regulates gut microbiota}, series = {Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry and pharmacology}, volume = {42}, journal = {Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry and pharmacology}, number = {1}, publisher = {Karger}, address = {Basel}, issn = {1015-8987}, doi = {10.1159/000477386}, pages = {306 -- 318}, year = {2017}, abstract = {Starch is one of the most popular nutritional sources for both human and animals. Due to the variation of its nutritional traits and biochemical specificities, starch has been classified into rapidly digestible, slowly digestible and resistant starch. Resistant starch has its own unique chemical structure, and various forms of resistant starch are commercially available. It has been found being a multiple-functional regulator for treating metabolic dysfunction. Different functions of resistant starch such as modulation of the gut microbiota, gut peptides, circulating growth factors, circulating inflammatory mediators have been characterized by animal studies and clinical trials. In this mini-review, recent remarkable progress in resistant starch on gut microbiota, particularly the effect of structure, biochemistry and cell signaling on nutrition has been summarized, with highlights on its regulatory effect on gut microbiota.}, language = {en} } @article{HeLiuLuetal.2017, author = {He, Jing and Liu, Zhi-Wei and Lu, Yong-Ping and Li, Tao-Yuan and Liang, Xu-Jing and Arck, Petra and Huang, Si-Min and Hocher, Berthold and Chen, You-Peng}, title = {A systematic review and meta-analysis of influenza a virus infection during pregnancy associated with an increased risk for stillbirth and low birth weight}, series = {Kidney \& blood pressure research : official organ of the Gesellschaft f{\"u}r Nephrologie ; official organ of the Deutsche Liga zur Bek{\"a}mpfung des Hohen Blutdruckes e.V., Deutsche Hypertonie-Gesellschaft}, volume = {42}, journal = {Kidney \& blood pressure research : official organ of the Gesellschaft f{\"u}r Nephrologie ; official organ of the Deutsche Liga zur Bek{\"a}mpfung des Hohen Blutdruckes e.V., Deutsche Hypertonie-Gesellschaft}, number = {2}, publisher = {Karger}, address = {Basel}, issn = {1420-4096}, doi = {10.1159/000477221}, pages = {232 -- 243}, year = {2017}, abstract = {Background/Aims: Impaired pregnancy outcomes, such as low birth weight are associated with increased disease risk in later life, however little is known about the impact of common infectious diseases during pregnancy on birth weight. The study had two aims: a) to investigate risk factors of influenza virus infection during pregnancy, and b) to analyze the impact of influenza virus infection on pregnancy outcome, especially birth weight. Methods: Prospective and retrospective observational studies found in PubMed, MEDLINE, Embase, Google Scholar, and WangFang database were included in this meta analysis. Data of included studies was extracted and analyzed by the RevMan software. Results: Pregnant women with anemia (P=0.004, RR=1.46, 95\% CI: 1.13-1.88), obesity (P<0.00001, RR=1.35, 95\% CI: 1.25-1.46) and asthma (P<0.00001, RR=1.99, 95\% CI: 1.67-2.37) had higher rates of influenza virus infection. Regarding birth outcomes, influenza A virus infection did not affect the likelihood for cesarean section. Mothers with influenza had a higher rate of stillbirth (P=0.04, RR=2.36, 95\% CI: 1.05-5.31), and their offspring had low 5-minute APGR Scores (P=0.009, RR=1.39, 95\% CI: 1.08-1.79). Furthermore, the rate for birth weight < 2500g (P=0.04, RR=1.71, 95\% CI: 1.03-2.84) was increased. Conclusion: Results of this study showed that anemia, asthma and obesity during pregnancy are risk factors influenza A virus infection during pregnancy. Moreover, gestational influenza A infection impairs pregnancy outcomes and increases the risk for low birth weight, a known risk factor for later life disease susceptibility.}, language = {en} } @article{ReichetzederHeunischvonEinemetal.2017, author = {Reichetzeder, Christoph and Heunisch, Fabian and von Einem, Gina-Franziska and Tsuprykov, Oleg and Kellner, Karl-Heinz and Dschietzig, Thomas and Kretschmer, Axel and Hocher, Berthold}, title = {Pre-interventional kynurenine predicts medium-term outcome after contrast media exposure due to coronary angiography}, series = {Kidney \& blood pressure research : official organ of the Gesellschaft f{\"u}r Nephrologie ; official organ of the Deutsche Liga zur Bek{\"a}mpfung des Hohen Blutdruckes e.V., Deutsche Hypertonie-Gesellschaft}, volume = {42}, journal = {Kidney \& blood pressure research : official organ of the Gesellschaft f{\"u}r Nephrologie ; official organ of the Deutsche Liga zur Bek{\"a}mpfung des Hohen Blutdruckes e.V., Deutsche Hypertonie-Gesellschaft}, number = {2}, publisher = {Karger}, address = {Basel}, issn = {1420-4096}, doi = {10.1159/000477222}, pages = {244 -- 256}, year = {2017}, abstract = {Background/Aims: Contrast induced acute kidney injury (CI-AKI) remains a serious complication of contrast media enhanced procedures like coronary angiography. There is still a lack of established biomarkers that help to identify patients at high risk for short and long-term complications. The aim of the current study was to evaluate plasma kynurenine as a predictive biomarker for CI-AKI and long-term complications, measured by the combined endpoint "major adverse kidney events" (MAKE) up to 120 days after CM application. Methods: In this prospective cohort study 245 patients undergoing coronary angiography were analyzed. Blood samples were obtained at baseline, 24h and 48h after contrast media (CM) application to diagnose CI-AKI. Patients were followed for 120 days for adverse clinical events including death, the need for dialysis, and a doubling of plasma creatinine. Occurrence of any of these events was summarized in the combined endpoint MAKE. Results: Preinterventional plasma kynurenine was not associated with CI-AKI. Patients who later developed MAKE displayed significantly increased preinterventional plasma kynurenine levels (p<0.0001). ROC analysis revealed that preinterventional kynurenine is highly predictive for MAKE (AUC=0.838; p<0.0001). The optimal cutoff was found at >= 3.5 mu mol/L. Using this cutoff, the Kaplan-Meier estimator demonstrated that concentrations of plasma kynurenine >= 3.5 mu mol/L were significantly associated with a higher prevalence of MAKE until follow up (p<0.0001). This association remained significant in multivariate Cox regression models adjusted for relevant factors of long-term renal outcome. Conclusion: Preinterventional plasma kynurenine might serve as a highly predictive biomarker for MAKE up to 120 days after coronary angiography.}, language = {en} } @article{XuLuHasanetal.2017, author = {Xu, Mei and Lu, Yong-Ping and Hasan, Ahmed A. and Hocher, Berthold}, title = {Plasma ET-1 concentrations are elevated in patients with hypertension meta-analysis of clinical studies}, series = {Kidney \& blood pressure research : official organ of the Gesellschaft f{\"u}r Nephrologie ; official organ of the Deutsche Liga zur Bek{\"a}mpfung des Hohen Blutdruckes e.V., Deutsche Hypertonie-Gesellschaft}, volume = {42}, journal = {Kidney \& blood pressure research : official organ of the Gesellschaft f{\"u}r Nephrologie ; official organ of the Deutsche Liga zur Bek{\"a}mpfung des Hohen Blutdruckes e.V., Deutsche Hypertonie-Gesellschaft}, number = {2}, publisher = {Karger}, address = {Basel}, issn = {1420-4096}, doi = {10.1159/000477572}, pages = {304 -- 313}, year = {2017}, abstract = {Background/Aims: A recent study revealed that global overexpression of ET-1 causes a slight reduction in systemic blood pressure. Moreover, heterozygous ET-1 knockout mice are hypertensive. The role of ET-1 in human hypertension was so far not addressed by a strict meta-analysis of published human clinical studies. Methods: We included studies published between January 1, 1990 and February 28, 2017. We included case control studies analyzing untreated essential hypertension or hypertensive patients where antihypertensive medication was discontinued for at least two weeks. Based on the principle of Cochrane systematic reviews, case control studies (CCSs) in PubMed (Medline) and Google Scholar designed to identify the role of endothelin-1 (ET-1) in the pathophysiological of hypertension were screened. Review Manager Version 5.0 (Rev-Man 5.0) was applied for statistical analysis. Mean difference and 95\% confidence interval (CI) were shown in inverse variance (IV) fixed-effects model or IV random-effects models. Results: Eleven studies fulfilling our in-and exclusion criteria were eligible for this meta-analysis. These studies included 450 hypertensive patients and 328 controls. Our meta-analysis revealed that ET-1 plasma concentrations were higher in hypertensive patients as compared to the control patients [mean difference between groups 1.57 pg/mL, 95\%Ci [0.47 similar to 2.68, P = 0.005]. These finding were driven by patients having systolic blood pressure higher than 160 mmHg and diastolic blood pressure higher than 100 mmHg. Conclusions: This meta-analysis showed that hypertensive patients do have elevated plasma ET-1 concentrations. This finding is driven by those patients with high systolic/diastolic blood pressure. Given that the ET-1 gene did not appear in any of the whole genome association studies searching for hypertension associated gene loci, it is very likely that the elevated plasma ET-1 concentrations in hypertensive patients are secondary to hypertension and may reflect endothelial cell damage.}, language = {en} } @article{WeckWitthoeft2017, author = {Weck, Florian and Witth{\"o}ft, Michael}, title = {Context effects in the evaluation of bodily symptoms}, series = {Journal of experimental psychopathology}, volume = {8}, journal = {Journal of experimental psychopathology}, publisher = {Sage Publishing}, address = {London}, issn = {2043-8087}, doi = {10.5127/jep.054216}, pages = {241 -- 251}, year = {2017}, abstract = {The illness-related evaluation of bodily symptoms is considered to be an important maintaining factor in somatoform disorders. However, little is known about context variables that could influence this evaluation process. In the current study, participants completed three versions of the Health Norms Sorting Task (HNST) and evaluated bodily symptoms in different contexts (i.e., different evaluation perspectives and time frames of evaluation). Additionally, the three HNST versions were presented in different orders. Bodily symptoms were evaluated more often as a sign of illness when a specific time frame (i.e., one week) was given. However, this context effect was only large when participants had previously evaluated symptoms existing without a concrete duration. Thus, previously completed symptom evaluations appear to represent an important frame of reference in terms of a cue that makes specific context variables salient. The results further suggested that these cueing effects might be less relevant for participants with elevated somatic symptom reports.}, language = {en} }