@article{IzraylitHommesSchattmannNeffeetal.2020,
  author    = {Izraylit, Victor and Hommes-Schattmann, Paul J. and Neffe, Axel T. and Gould, Oliver E. C. and Lendlein, Andreas},
  title     = {Polyester urethane functionalizable through maleimide side-chains and cross-linkable by polylactide stereocomplexes},
  series = {European polymer journal},
  volume    = {137},
  journal   = {European polymer journal},
  publisher = {Elsevier},
  address   = {Oxford},
  issn      = {0014-3057},
  doi       = {10.1016/j.eurpolymj.2020.109916},
  pages     = {8},
  year      = {2020},
  abstract  = {Sustainable multifunctional alternatives to fossil-derived materials, which can be functionalized and are degradable, can be envisioned by combining naturally derived starting materials with an established polymer design concept. Modularity and chemical flexibility of polyester urethanes (PEU) enable the combination of segments bearing functionalizable moieties and the tailoring of the mechanical and thermal properties. In this work, a PEU multiblock structure was synthesized from naturally derived L-lysine diisocyanate ethyl ester (LDI), poly(L-lactide) diol (PLLA) and N-(2,3-dihydroxypropyl)-maleimide (MID) in a one-step reaction. A maleimide side-chain (MID) provided a reactive site for the catalyst-free coupling of thiols shown for L-cysteine with a yield of 94\%. Physical cross-links were generated by blending the PEU with poly(D-lactide) (PDLA), upon which the PLLA segments of the PEU and the PDLA formed stereocomplexes. Stereocomplexation occurred spontaneously during solution casting and was investigated with WAXS and DSC. Stereocomplex crystallites were observed in the blends, while isotactic PLA crystallization was not observed. The presented material platform with tailorable mechanical properties by blending is of specific interest for engineering biointerfaces of implants or carrier systems for bioactive molecules.},
  language  = {en}
}
@phdthesis{Zarafshani2012,
  author    = {Zarafshani, Zoya},
  title     = {Chain-end functionalization and modification of polymers using modular chemical reactions},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-59723},
  school      = {Universit{\"a}t Potsdam},
  year      = {2012},
  abstract  = {Taking advantage of ATRP and using functionalized initiators, different functionalities were introduced in both α and ω chain-ends of synthetic polymers. These functionalized polymers could then go through modular synthetic pathways such as click cycloaddition (copper-catalyzed or copper-free) or amidation to couple synthetic polymers to other synthetic polymers, biomolecules or silica monoliths. Using this general strategy and designing these co/polymers so that they are thermoresponsive, yet bioinert and biocompatible with adjustable cloud point values (as it is the case in the present thesis), the whole generated system becomes "smart" and potentially applicable in different branches. The applications which were considered in the present thesis were in polymer post-functionalization (in situ functionalization of micellar aggregates with low and high molecular weight molecules), hydrophilic/hydrophobic tuning, chromatography and bioconjugation (enzyme thermoprecipitation and recovery, improvement of enzyme activity). Different α-functionalized co/polymers containing cholesterol moiety, aldehyde, t-Boc protected amine, TMS-protected alkyne and NHS-activated ester were designed and synthesized in this work.},
  language  = {en}
}