@article{LacroixKressigMuehlbaueretal.2016,
  author    = {Lacroix, Andre and Kressig, Reto W. and M{\"u}hlbauer, Thomas and Gschwind, Yves J. and Pfenninger, Barbara and Bruegger, Othmar and Granacher, Urs},
  title     = {Effects of a Supervised versus an Uniupervised Combined Balance and Strength Training Program on Balance and Muscle Power in Healthy Older Adults: A Randomized Controlled Trial},
  series = {Gerontology},
  volume    = {62},
  journal   = {Gerontology},
  publisher = {Karger},
  address   = {Basel},
  issn      = {0304-324X},
  doi       = {10.1159/000442087},
  pages     = {275 -- 288},
  year      = {2016},
  abstract  = {Background: Losses in lower extremity muscle strength/power, muscle mass and deficits in static and particularly dynamic balance due to aging are associated with impaired functional performance and an increased fall risk. It has been shown that the combination of balance and strength training (BST) mitigates these age-related deficits. However, it is unresolved whether supervised versus unsupervised BST is equally effective in improving muscle power and balance in older adults. Objective:This study examined the impact of a 12-week BST program followed by 12 weeks of detraining on measures of balance and muscle power in healthy older adults enrolled in supervised (SUP) or unsupervised (UNSUP) training. Methods: Sixty-six older adults (men: 25, women: 41; age 73 4 years) were randomly assigned to a SUP group (2/week supervised training, 1/week unsupervised training; n = 22), an UNSUP group (3/week unsupervised training; n = 22) or a passive control group (CON; n = 22). Static (i.e., Romberg Test) and dynamic (i.e., 10-meter walk test) steady-state, proactive (i.e., Timed Up and Go Test, Functional Reach Test), and reactive balance (e.g., Push and Release Test), as well as lower extremity muscle power (i.e., Chair Stand Test; Stair Ascent and Descent Test) were tested before and after the active training phase as well as after detraining. Results: Adherence rates to training were 92\% for SUP and 97\% for UNSUP. BST resulted in significant group x time interactions. Post hoc analyses showed, among others, significant training-related improvements for the Romberg Test, stride velocity, Timed Up and Go Test, and Chair Stand Test in favor of the SUP group. Following detraining, significantly enhanced performances (compared to baseline) were still present in 13 variables for the SUP group and in 10 variables for the UNSUP group. Conclusion: Twelve weeks of BST proved to be safe (no training-related injuries) and feasible (high attendance rates of >90\%). Deficits of balance and lower extremity muscle power can be mitigated by BST in healthy older adults. Additionally, supervised as compared to unsupervised BST was more effective. Thus, it is recommended to counteract intrinsic fall risk factors by applying supervised BST programs for older adults. (C) 2015 The Author(s) Published by S. Karger AG, Basel},
  language  = {en}
}
@article{MuellerStollMuelleretal.2018,
  author    = {Mueller, Juliane and Stoll, Josefine and Mueller, Steffen and Mayer, Frank},
  title     = {Dose-response relationship of core-specific sensorimotor interventions in healthy, welltrained participants},
  series = {Trials},
  volume    = {19},
  journal   = {Trials},
  number    = {424},
  publisher = {BioMed Central},
  address   = {London},
  issn      = {1745-6215},
  doi       = {10.1186/s13063-018-2799-9},
  pages     = {8},
  year      = {2018},
  abstract  = {Background: Core-specific sensorimotor exercises are proven to enhance neuromuscular activity of the trunk, improve athletic performance and prevent back pain. However, the dose-response relationship and, therefore, the dose required to improve trunk function is still under debate. The purpose of the present trial will be to compare four different intervention strategies of sensorimotor exercises that will result in improved trunk function. Methods/design: A single-blind, four-armed, randomized controlled trial with a 3-week (home-based) intervention phase and two measurement days pre and post intervention (M1/M2) is designed. Experimental procedures on both measurement days will include evaluation of maximum isokinetic and isometric trunk strength (extension/flexion, rotation) including perturbations, as well as neuromuscular trunk activity while performing strength testing. The primary outcome is trunk strength (peak torque). Neuromuscular activity (amplitude, latencies as a response to perturbation) serves as secondary outcome. The control group will perform a standardized exercise program of four sensorimotor exercises (three sets of 10 repetitions) in each of six training sessions (30 min duration) over 3 weeks. The intervention groups' programs differ in the number of exercises, sets per exercise and, therefore, overall training amount (group I: six sessions, three exercises, two sets; group II: six sessions, two exercises, two sets; group III: six sessions, one exercise, three sets). The intervention programs of groups I, II and III include additional perturbations for all exercises to increase both the difficulty and the efficacy of the exercises performed. Statistical analysis will be performed after examining the underlying assumptions for parametric and non-parametric testing. Discussion: The results of the study will be clinically relevant, not only for researchers but also for (sports) therapists, physicians, coaches, athletes and the general population who have the aim of improving trunk function.},
  language  = {en}
}
@misc{MuellerStollMuelleretal.2019,
  author    = {Mueller, Juliane and Stoll, Josefine and Mueller, Steffen and Mayer, Frank},
  title     = {Dose-response relationship of core-specific sensorimotor interventions in healthy, welltrained participants},
  series = {Postprints der Universit{\"a}t Potsdam Humanwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam Humanwissenschaftliche Reihe},
  number    = {499},
  issn      = {1866-8364},
  doi       = {10.25932/publishup-42241},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-422414},
  year      = {2019},
  abstract  = {Background: Core-specific sensorimotor exercises are proven to enhance neuromuscular activity of the trunk, improve athletic performance and prevent back pain. However, the dose-response relationship and, therefore, the dose required to improve trunk function is still under debate. The purpose of the present trial will be to compare four different intervention strategies of sensorimotor exercises that will result in improved trunk function. Methods/design: A single-blind, four-armed, randomized controlled trial with a 3-week (home-based) intervention phase and two measurement days pre and post intervention (M1/M2) is designed. Experimental procedures on both measurement days will include evaluation of maximum isokinetic and isometric trunk strength (extension/flexion, rotation) including perturbations, as well as neuromuscular trunk activity while performing strength testing. The primary outcome is trunk strength (peak torque). Neuromuscular activity (amplitude, latencies as a response to perturbation) serves as secondary outcome. The control group will perform a standardized exercise program of four sensorimotor exercises (three sets of 10 repetitions) in each of six training sessions (30 min duration) over 3 weeks. The intervention groups' programs differ in the number of exercises, sets per exercise and, therefore, overall training amount (group I: six sessions, three exercises, two sets; group II: six sessions, two exercises, two sets; group III: six sessions, one exercise, three sets). The intervention programs of groups I, II and III include additional perturbations for all exercises to increase both the difficulty and the efficacy of the exercises performed. Statistical analysis will be performed after examining the underlying assumptions for parametric and non-parametric testing. Discussion: The results of the study will be clinically relevant, not only for researchers but also for (sports) therapists, physicians, coaches, athletes and the general population who have the aim of improving trunk function.},
  language  = {en}
}
@article{MuellerStollMuelleretal.2018,
  author    = {M{\"u}ller, Juliane and Stoll, Josefine and Mueller, Steffen and Mayer, Frank},
  title     = {Dose-response relationship of core-specific sensorimotor interventions in healthy, well-trained participants},
  series = {Trials},
  volume    = {19},
  journal   = {Trials},
  publisher = {BMC},
  address   = {London},
  issn      = {1745-6215},
  doi       = {10.1186/s13063-018-2799-9},
  pages     = {8},
  year      = {2018},
  abstract  = {Background: Core-specific sensorimotor exercises are proven to enhance neuromuscular activity of the trunk, improve athletic performance and prevent back pain. However, the dose-response relationship and, therefore, the dose required to improve trunk function is still under debate. The purpose of the present trial will be to compare four different intervention strategies of sensorimotor exercises that will result in improved trunk function. Discussion: The results of the study will be clinically relevant, not only for researchers but also for (sports) therapists, physicians, coaches, athletes and the general population who have the aim of improving trunk function.},
  language  = {en}
}
@article{NiedererVogtWippertetal.2016,
  author    = {Niederer, Daniel and Vogt, Lutz and Wippert, Pia-Maria and Puschmann, Anne-Katrin and Pfeifer, Ann-Christin and Schiltenwolf, Marcus and Banzer, Winfried and Mayer, Frank},
  title     = {Medicine in spine exercise (MiSpEx) for nonspecific low back pain patients: study protocol for a multicentre, single-blind randomized controlled trial},
  series = {Trials},
  volume    = {17},
  journal   = {Trials},
  publisher = {BioMed Central},
  address   = {London},
  issn      = {1745-6215},
  doi       = {10.1186/s13063-016-1645-1},
  pages     = {9},
  year      = {2016},
  abstract  = {Background: Arising from the relevance of sensorimotor training in the therapy of nonspecific low back pain patients and from the value of individualized therapy, the present trial aims to test the feasibility and efficacy of individualized sensorimotor training interventions in patients suffering from nonspecific low back pain. Methods and study design: A multicentre, single-blind two-armed randomized controlled trial to evaluate the effects of a 12-week (3 weeks supervised centre-based and 9 weeks home-based) individualized sensorimotor exercise program is performed. The control group stays inactive during this period. Outcomes are pain, and pain-associated function as well as motor function in adults with nonspecific low back pain. Each participant is scheduled to five measurement dates: baseline (M1), following centre-based training (M2), following home-based training (M3) and at two follow-up time points 6 months (M4) and 12 months (M5) after M1. All investigations and the assessment of the primary and secondary outcomes are performed in a standardized order: questionnaires - clinical examination biomechanics (motor function). Subsequent statistical procedures are executed after the examination of underlying assumptions for parametric or rather non-parametric testing. Discussion: The results and practical relevance of the study will be of clinical and practical relevance not only for researchers and policy makers but also for the general population suffering from nonspecific low back pain.},
  language  = {en}
}
@article{WippertDeWittHubertsKlipkeretal.2015,
  author    = {Wippert, Pia-Maria and De Witt Huberts, Jessie and Klipker, Kathrin and Gantz, Simone and Schiltenwolf, Marcus and Mayer, Frank},
  title     = {Development and content of the behavioral therapy module of the MiSpEx intervention. Randomized, controlled trial on chronic nonspecific low back pain},
  series = {Der Schmerz : Organ der Deutschen Gesellschaft zum Studium des Schmerzes, der {\"O}sterreichischen Schmerzgesellschaft und der Deutschen Interdisziplin{\"a}ren Vereinigung f{\"u}r Schmerztherapie},
  volume    = {29},
  journal   = {Der Schmerz : Organ der Deutschen Gesellschaft zum Studium des Schmerzes, der {\"O}sterreichischen Schmerzgesellschaft und der Deutschen Interdisziplin{\"a}ren Vereinigung f{\"u}r Schmerztherapie},
  number    = {6},
  publisher = {Springer},
  address   = {New York},
  issn      = {0932-433X},
  doi       = {10.1007/s00482-015-0044-y},
  pages     = {658 -- 663},
  year      = {2015},
  abstract  = {Back pain is a complex phenomenon that goes beyond a simple medical diagnosis. The aetiology and chronification of back pain can be best described as an interaction between biological, psychological, and social processes. However, to date, multimodal prevention and intervention programs for back pain that target all three aetiological factors have demonstrated limited effectiveness. This lack of supportive evidence for multimodal programmes in the treatment of back pain could be due to the fact that few programs are suitable for long-term and unsupervised use in everyday life. Moreover, in combining the elements from various therapies, little attention has been paid to the mechanisms underlying the synergistic effects of the separate components. In this contribution, we will describe the development of a new multimodal intervention for back pain that set out to address these limitations. To this end, the biological elements of neuromuscular adaptation is supplemented with cognitive behavioral and psychophysiological techniques in an intervention that can be followed at home as well as in clinics, and that is suitable for all grades of pain. The efficacy of this intervention will be tested in a multicentric randomized controlled longitudinal trial (n = 714) at five time points over a period of 6 months. Here we will describe the development and the content of this new intervention.},
  language  = {de}
}