@misc{PacholskiAgarwalBalderasValadez2016,
  author    = {Pacholski, Claudia and Agarwal, Vivechana and Balderas-Valadez, Ruth Fabiola},
  title     = {Fabrication of porous silicon-based optical sensors using metal-assisted chemical etching},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-394426},
  pages     = {21430 -- 21434},
  year      = {2016},
  abstract  = {Optical biosensors based on porous silicon were fabricated by metal assisted chemical etching. Thereby double layered porous silicon structures were obtained consisting of porous pillars with large pores on top of a porous silicon layer with smaller pores. These structures showed a similar sensing performance in comparison to electrochemically produced porous silicon interferometric sensors.},
  language  = {en}
}
@article{BalderasValadezAgarwalPacholski2016,
  author    = {Balderas-Valadez, Ruth Fabiola and Agarwal, Vivechana and Pacholski, Claudia},
  title     = {Fabrication of porous silicon-based optical sensors using metal-assisted chemical etching},
  series = {RSC Advances},
  volume    = {6},
  journal   = {RSC Advances},
  publisher = {Royal Society of Chemistry},
  address   = {Cambridge},
  issn      = {2046-2069},
  doi       = {10.1039/c5ra26816h},
  pages     = {21430 -- 21434},
  year      = {2016},
  abstract  = {Optical biosensors based on porous silicon were fabricated by metal assisted chemical etching. Thereby double layered porous silicon structures were obtained consisting of porous pillars with large pores on top of a porous silicon layer with smaller pores. These structures showed a similar sensing performance in comparison to electrochemically produced porous silicon interferometric sensors.},
  language  = {en}
}
@article{FallahStanglmairPacholskietal.2016,
  author    = {Fallah, Mohammad A. and Stanglmair, Christoph and Pacholski, Claudia and Hauser, Karin},
  title     = {Devising Self-Assembled-Monolayers for Surface-Enhanced Infrared Spectroscopy of pH-Driven Poly-L-lysine Conformational Changes},
  series = {Langmuir},
  volume    = {32},
  journal   = {Langmuir},
  publisher = {American Chemical Society},
  address   = {Washington},
  issn      = {0743-7463},
  doi       = {10.1021/acs.langmuir.6b01742},
  pages     = {7356 -- 7364},
  year      = {2016},
  abstract  = {Surface-enhanced infrared absorption spectroscopy (SEIRA) is applied to study protein conformational changes. In general, the appropriate functionalization of metal surfaces with biomolecules remains a challenge if the conformation and activity of the biomolecule shall be preserved. Here we present a SEIRA study to monitor pH-induced conformational changes of poly-L lysine (PLL) covalently bound to a thin gold layer via self assembled monolayers (SAMs). We demonstrate that the composition of the SAM is crucial. A SAM of 11-mercaptoundecanonic acid (MUA) can link PLL to the gold layer, but pH-driven conformational transitions were hindered compared to poly-L lysine in solution. To address this problem, we devised a variety of SAMs, i.e., mixed SAMs of MUA with either octanethiol (OT) or 11-mercapto-1-undecanol (MUoL) and furthermore SAMs of MT(PEG)(4) and NHS-PEG(10k)-SH. These mixed SAMs modify the surface properties by changing the polarity and the morphology of the surface present to nearby PLL molecules. Our experiments reveal that mixed SAMs of MUA-MUoL and SAMs of NHS-PEG(10k)-SH-MT(PEG)(4) are suitable to monitor pH-driven conformational changes of immobilized PLL. These SAMs might be applicable for chemoselective protein immobilization in general.},
  language  = {en}
}
@article{WeilerMenzelPertschetal.2016,
  author    = {Weiler, Markus and Menzel, Christoph and Pertsch, Thomas and Alaee, Rasoul and Rockstuhl, Carsten and Pacholski, Claudia},
  title     = {Bottom-Up Fabrication of Hybrid Plasmonic Sensors: Gold-Capped Hydrogel Microspheres Embedded in Periodic Metal Hole Arrays},
  series = {Polymer : the international journal for the science and technology of polymers},
  volume    = {8},
  journal   = {Polymer : the international journal for the science and technology of polymers},
  publisher = {American Chemical Society},
  address   = {Washington},
  issn      = {1944-8244},
  doi       = {10.1021/acsami.6b08636},
  pages     = {26392 -- 26399},
  year      = {2016},
  abstract  = {The high potential of bottom-up fabrication strategies for realizing sophisticated optical sensors combining the high sensitivity of a surface plasmon resonance with the exceptional properties of stimuli-responsive hydrogel is demonstrated. The sensor is composed of a periodic hole array in a gold film whose holes are filled with gold-capped poly(N-isoproyl-acrylamide) (polyNIPAM) microspheres. The production of this sensor relies on a pure chemical approach enabling simple, time-efficient, and cost-efficient preparation of sensor platforms covering areas of cm(2). The transmission spectrum of this plasmonic sensor shows a strong interaction between propagating surface plasmon polaritons at the metal film surface and localized surface plasmon resonance of the gold cap on top of the polyNIPAM microspheres. Computer simulations support this experimental observation. These interactions lead to distinct changes in the transmission spectrum, which allow for the simultaneous, sensitive optical detection of refractive index changes in the surrounding medium and the swelling state of the embedded polyNIPAM microsphere under the gold cap. The volume of the polyNIPAM microsphere located underneath the gold cap can be changed by certain stimuli such as temperature, pH, ionic strength, and distinct molecules bound to the hydrogel matrix facilitating the detection of analytes which do not change the refractive index of the surrounding medium significantly.},
  language  = {en}
}