@article{Mussil2001, author = {Mussil, Stephan}, title = {Why Hamlet delays: reflexivity in literature and criticism}, issn = {1382-5577}, year = {2001}, language = {en} } @article{EcksteinLutz2001, author = {Eckstein, Lars and Lutz, Andrea}, title = {Literary missions and global ethic}, isbn = {3-86057-741-7}, year = {2001}, language = {en} } @article{Eckstein2001, author = {Eckstein, Lars}, title = {Getting back to the idea of art as art : an interview with David Dabydeen}, year = {2001}, language = {en} } @article{Eckstein2001, author = {Eckstein, Lars}, title = {The insistence of voices : an interview with Caryl Phillips}, year = {2001}, language = {en} } @article{Eckstein2001, author = {Eckstein, Lars}, title = {Dialogism in Caryl Phillips"s Cambridge, or the Democratisation of cultural memory}, year = {2001}, language = {en} } @article{NorledgeLambeirAbagyanetal.2001, author = {Norledge, Brian V. and Lambeir, Anne M. and Abagyan, Ruben and Rottmann, Antje and Fernendez, Anna M. and Filimonov, Vladimir V. and Peter, Martin G. and Wierenga, Rik K.}, title = {Modeling, mutagenesis, and structural studies on the fully conserved phoshate-binding loop (Loop 8) of triosephosphate isomerase : toward a new substrate specificity}, issn = {0887-2585}, year = {2001}, language = {en} } @article{FedosovSchulzeTarkhanov2001, author = {Fedosov, Boris and Schulze, Bert-Wolfgang and Tarkhanov, Nikolai Nikolaevich}, title = {A general index formula on toric manifolds with conical point}, year = {2001}, language = {en} } @article{Schulze2001, author = {Schulze, Bert-Wolfgang}, title = {Operator algebras with symbol hierarchies on manifolds with singularities}, year = {2001}, language = {en} } @article{GrotjahnLehmannAurichetal.2001, author = {Grotjahn, Manuela and Lehmann, S. and Aurich, Ines and Holdt, Hans-Joachim and Kleinpeter, Erich}, title = {NMR spectroscopic and molecular modelling studies of the solution structure and complexational behaviour of some bis(benzocrown ether)s}, year = {2001}, abstract = {Structural information about the bis(benzo crown ether)s I-VI and their complexes with alkali metal cations was deduced from the 13C NMR chemical shifts, the salt-induced 1H and 13C chemical shifts and the vicinal 1H,1H coupling constants. Especially the isomerism with respect to the amide O=C - NH bonds and imine fragments were assigned by various useful NMR parameters ( C=O, 1JN,H, 1JC,H) and proved to be E,E-anti,anti. Furthermore, stereochemical information about preferred conformations about flexible bonds was obtained from 2D ROESY NMR experiments. The complex formation (2:1 complexes and sandwich-like 1:1 complexes, respectively) were determined also by 23Na NMR spectroscopy. The conformational study of the crown ethers was accompanied and corroborated by molecular dynamics and quantum chemical calculations.}, language = {en} } @article{JansenBuschmannWegoetal.2001, author = {Jansen, K. and Buschmann, Hans-J{\"u}rgen and Wego, A. and Dopp, D. and Mayer, C. and Holdt, Hans-Joachim and Schollmeyer, E.}, title = {Curcubit[5]uril, decamethylcururbit[5]uril and curcurbit[6]uril : synthesis, solubility and amin complex formation}, year = {2001}, abstract = {A simple way to prepare cucurbit[5]uril is described. The macrocycles of the cucurbituril type are nearly insoluble in water. The solubilities of cucurbit[5]uril, decamethylcucurbit[5]uril and cucurbit[6]uril in hydrochloric acid, formic acid and acetic acid of different concentrations have been investigated. Due to the formation of complexes between cucurbit[n]urils and protons the solubility increases in aqueous acids. The macrocyclic ligands are able to form complexes with several organic compounds. Thus, the complex formation of the cucurbituril macrocycles with different amines has beenstudied by means of calorimetric titrations. The reaction enthalpy gives noevidence of the formation of inclusion or exclusion complexes. 1H-NMR measurements show that in the case of cucurbit[5]uril and cucurbit[6]uril the organic guest compound is included within the hydrophobic cavity. Decamethylcucurbit[5]uril forms only exclusion complexes with organicamines. This was confirmed by the crystal structure of the decamethylcucurbit[5]uril-1,6- diaminohexane complex. complex formation - cucurbit[5]uril - cucurbit[6]uril - decamethylcucurbit[5]uril - solubility - synthesis}, language = {en} } @article{HoldtDrexlerStarkeetal.2001, author = {Holdt, Hans-J{\"u}rgen and Drexler, Hans-Joachim and Starke, Ines and Grotjahn, Manuela and Kleinpeter, Erich}, title = {Homologous series of the PdCl2 and PtCl2 complexes of maleonitrile-dithiacrown ethers : synthesis, crystal structures, NMR spectroscopy and mass spectrometry}, year = {2001}, language = {en} } @article{KleinpeterGrotjahnKlinkaetal.2001, author = {Kleinpeter, Erich and Grotjahn, Manuela and Klinka, Karel D. and Drexler, Hans-Joachim and Holdt, Hans-J{\"u}rgen}, title = {Conformational and complexational study of some maleonitrile mixed oxadithia crown ethers by NMR spectroscopy and molecular modelling}, year = {2001}, abstract = {The macrocyclic ring interconversion of four maleonitrile mixed oxadithia crown ethers of variable ring size, mn-12-S2O2, mn-15-S2O3, mn-18-S2O4 and fn-12-S2O2, were studied by 1H and 13C NMR spectroscopy and by molecular modelling. The barriers to ring interconversion were estimated using variable temperature NMR spectroscopy and from the calculated activation energies, together with the spin-lattice relaxation times of the CH2 carbon atoms, conclusions were drawn regarding the intramolecular flexibility of the crown ethers in both the free state as well as the complexed state incorporating either AgI, BiIII, SbIII, PdII or PtII metal cations. Furthermore, both the stoichiometry of the complexes and the coordination sites of the crown ethers to the various cations were also clearly implicated. Molecular modelling was also utilised to ascertain the preferred conformers of the four compounds and their corresponding complexes, the results of which corroborated the experimental NMR results to a high degree.}, language = {en} } @article{DoerfelBaasenRauh2001, author = {Doerfel-Baasen, Dorothee and Rauh, Hellgard}, title = {Parents an dteachers of young children under conditions of sociopolitical change}, year = {2001}, language = {en} } @article{Schubert2001, author = {Schubert, Hans-Joachim}, title = {Social Organization}, year = {2001}, language = {en} } @article{Schneider2001, author = {Schneider, Ingo}, title = {Microbiological and Enzymatic Inverstigations of soils in the Rustenburg Mining Area}, year = {2001}, abstract = {In soils of the Rustenbug Minig Area microorganism concentration and activity of several enzymes (dehydrogenase, phosphatase, protease, amylase, cellulase, xylanase) were determined. First results indicate an increase of heavy metal resistant Microorganisms and a possible inhibition of carbohydrate degrading enzymes.}, language = {en} } @article{WilsonChawdhuryAlMandharyetal.2001, author = {Wilson, J. S. and Chawdhury, Nazia and Al-Mandhary, Muna R. A. and Younus, M. and Khan, Muhammad S. and Raithby, Paul R. and Friend, Richard H.}, title = {The energy gap law for triplet States in Pt-containing conjugated polymers and monomers}, year = {2001}, language = {en} } @article{WackervonElert2001, author = {Wacker, Alexander and von Elert, Eric}, title = {Polyunsaturated fatty acids : evidence for non-substitutable biochemical resources in daphnia galeata}, year = {2001}, abstract = {The factors that determine the efficiency of energy transfer in aquatic food webs have been investigated for many decades. The plant-animal interface is the most variable and least predictable of all levels in the food web. In order to study determinants of food quality in a large lake and to test the recently proposed central importance of the long-chained eicosapentaenoic acid (EPA) at the pelagic producer-grazer interface, we tested the importance of polyunsaturated fatty acids (PUFAs) at the pelagic producer-consumer interface by correlating sestonic food parameters with somatic growth rates of a clone of Daphnia galeata. Daphnia growth rates were obtained from standardized laboratory experiments spanning one season with Daphnia feeding on natural seston from Lake Constance, a large pre-alpine lake. Somatic growth rates were fitted to sestonic parameters by using a saturation function. A moderate amount of variation was explained when the model included the elemental parameters carbon (r2 = 0.6) and nitrogen (r2 = 0.71). A tighter fit was obtained when sestonic phosphorus was incorporated (r2 = 0.86). The nonlinear regression with EPA was relatively weak (r2 = 0.77), whereas the highest degree of variance was explained by three C18-PUFAs. The best (r2 = 0.95), and only significant, correlation of Daphnia's growth was found with the C18-PUFA a-linolenic acid (a-LA; C18:3n-3). This correlation was weakest in late August when C:P values increased to 300, suggesting that mineral and PUFA- limitation of Daphnia's growth changed seasonally. Sestonic phosphorus and some PUFAs showed not only tight correlations with growth, but also with sestonic alpha-LA content. We computed Monte Carlo simulations to test whether the observed effects of alpha-LA on growth could be accounted for by EPA, phosphorus, or one of the two C18-PUFAs, stearidonic acid (C18:4n-3) and linoleic acid (C18:2n-6). With >99\% probability, the correlation of growth with alpha-LA could not be explained by any of these parameters. In order to test for EPA limitation of Daphnia's growth, in parallel with experiments on pure seston, growth was determined on seston supplemented with chemostat-grown, Plimited Stephanodiscus hantzschii, which is rich in EPA. Although supplementation increased the EPA content 80-800x, no significant changes in the nonlinear regression of the growth rates with alpha-LA were found, indicating that growth of Daphnia on pure seston was not EPA limited. This indicates that the two fatty acids, EPA and alpha-LA, were not mutually substitutable biochemical resources and points to different physiological functions of these two PUFAs. These results support the PUFA-limitation hypothesis for sestonic C:P < 300 but are contrary to the hypothesis of a general importance of EPA, since no evidence for EPA limitation was found. It is suggested that the resource ratios of EPA and alpha-LA rather than the absolute concentrations determine which of the two resources is limiting growth.}, language = {en} } @article{Fischer2001, author = {Fischer, Markus}, title = {The role of vegetative spread and seed dispersal for optimal life histories of clonal plants : a simulation study}, year = {2001}, language = {en} } @article{FischerMuellerSchaerer2001, author = {Fischer, Markus and M{\"u}ller-Sch{\"a}rer, H.}, title = {Genetic structure of the annual weed Senecio vulgaris in relation to habitat type and population size}, year = {2001}, language = {en} } @article{FischerKeryMatthies2001, author = {Fischer, Markus and K{\´e}ry, M. and Matthies, D.}, title = {The effect of plant population size on the interactions between the rare plant Gentiana cruciata and its specialized herbivore Maculinea rebeli}, year = {2001}, language = {en} } @article{Petersen2001, author = {Petersen, Hans-Georg}, title = {Economic Aspects of Agricultural Areas Management and Land/Water Ecotones Conservation}, year = {2001}, language = {en} } @article{AnishchenkoVadivasovaKopeikinetal.2001, author = {Anishchenko, Vadim S. and Vadivasova, T. E. and Kopeikin, A. S. and Kurths, J{\"u}rgen and Strelkova, G. I.}, title = {Effect of noise on the relaxation to an invariant probability measure of nonhyperbolic chaotic attractors}, year = {2001}, language = {en} } @article{Giest2001, author = {Giest, Hartmut}, title = {Instruction and learning in elementary school}, isbn = {87-7288-841-5}, year = {2001}, language = {en} } @article{LindnerFreeseQuehletal.2001, author = {Lindner, A. and Freese, H. and Quehl, G. and Reiß, D. and Schiller, K.}, title = {Jaynes-Cummings-model with damping at resonance}, issn = {1434-6060}, year = {2001}, language = {en} } @article{DalyBalaganskyTimmermanetal.2001, author = {Daly, J. S. and Balagansky, V. V. and Timmerman, Martin Jan and Whitehouse, M. J. and de Jong, K. and Guise, P. and Bogdanova, S. and Gorbatschev, R. and Bridgwater, D.}, title = {Ion microprobe U-Pb zircon geochronology and isotopic evidence for a trans-crustal suture in the Lapland-Kola Orogen, northern Fennoscandian Shield}, year = {2001}, language = {en} } @article{BridgwaterScottBalaganskyetal.2001, author = {Bridgwater, D. and Scott, D. J. and Balagansky, V. V. and Timmerman, Martin Jan and Marker, Michael and Bushmin, S. S. and Alexeyev, N. L. and Daly, J. S.}, title = {Age and provenance of early Precambrian metasedimentary rocks in the Lapland-Kola Belt, Russia : evidence from Pb and Nd isotopic data}, year = {2001}, language = {en} } @article{PecherSpahnSchirrmannetal.2001, author = {Pecher, Gabriele and Spahn, Gunter and Schirrmann, Thomas and Kulbe, Hagen and Ziegner, Maja and Schenk, J{\"o}rg A. and Sandig, Volker}, title = {Mucin gene (MUC1) transfer into human dendritic cells by cationic liposomes and recombinant adenovirus}, issn = {0250-7005}, year = {2001}, abstract = {BACKGROUND: Dendritic cells (DC) as antigen presenting cells play an important role in immunotherapy of cancer. Mucin, encoded by the gene MUC1, is a human tumor antigen expressed in breast, pancreatic and ovarian cancers. Therefore, MUC1-transfected DC would be an attractive tool in constructing cancer vaccines. MATERIALS AND METHODS: Using two different cationic liposome preparations and, for comparison, a recombinant adenovirus expressing mucin, we tested the efficiency of mucin gene transfer into DC by flow cytometry. We investigated if these transfected DC were able to specifically stimulate autologous peripheral blood lymphocytes (PBL) from healthy donors. RESULTS: Flow cytometry revealed that 5-20\% of DC transfected with liposomes Lipofectin and 20-40\% of DC transduced with adenovirus expressed the relevant mucin epitopes. The expression of mucin on DC was similar to the expression of mucin found on carcinoma cells. After antigen uptake, DC specifically stimulated autologous PBL. CONCLUSION: We have shown that cationic liposomal gene transfer into human DC was feasible. We could obtain antigen specific stimulation of PBL at a similar rate as with adenoviral MUC1-transduced DC.}, language = {en} } @article{PecherHarnackGuntheretal.2001, author = {Pecher, Gabriele and Harnack, U. and Gunther, M. and Hummel, M. and Fichtner, I. and Schenk, J{\"o}rg A.}, title = {Generation of an immortalized human CD4+ T cell clone inhibiting tumor growth in mice.}, year = {2001}, abstract = {Tumor antigen-specific T cell clones represent a useful tool in tumor immunology; however, their long-term culture is limited. To generate an immortalized cytotoxic T cell clone against the human tumor antigen mucin, we exposed a previously generated T cell culture to Herpesvirus saimiri. We obtained an immortalized human CD4+ T cell clone, termed SITAM. Clonality of these cells was shown by analysis of the alpha/beta-T cell receptor (TCR) repertoire. Cytolytic activity was demonstrated against several mucin-expressing tumor cell lines and could not be detected against non-mucin-expressing cells. SITAM cells maintained their features stably for 2 years. Furthermore, growth of the tumor cell line Capan-2 in NOD/SCID mice was inhibited when SITAM cells were coinjected subcutaneously with tumor cells. SITAM cells provide an unlimited source of clonal T cells for analysis of tumor recognition and may be of help in TCR-targeted immunotherapy.}, language = {en} } @article{BergholzHeymannSchenketal.2001, author = {Bergholz, Andr{\´e} and Heymann, Stephan and Schenk, J{\"o}rg A. and Freytag, Johann Christoph}, title = {Biological sequences integrated: a relational database approach}, year = {2001}, abstract = {Over the last decade the modeling and the storage of biological data has been a topic of wide interest for scientists dealing with biological and biomedical research. Currently most data is still stored in text files which leads to data redundancies and file chaos. In this paper we show how to use relational modeling techniques and relational database technology for modeling and storing biological sequence data, i.e. for data maintained in collections like EMBL or SWISS-PROT to better serve the needs for these application domains. For this reason we propose a two step approach. First, we model the structure (and therefore the meaning of the) data using an Entity-Relationship approach. The ER model leads to a clean design of a relational database schema for storing and retrieving the DNA and protein data extracted from various sources. Our approach provides the clean basis for building complex biological applications that are more amenable to changes and software ports than their file-base counterparts.}, language = {en} } @article{BalaganskyTimmermanKozlovaetal.2001, author = {Balagansky, V. V. and Timmerman, Martin Jan and Kozlova, N. Ye. and Kisilitsyn, R. V.}, title = {A 2.44 Ga old mafic dyke swarm in the Kolvitsa Belt, Kola Peninsula, Russia: implications for the early Palaeoproterozoic tectonics in the north-eastern Fennoscandian Shield}, year = {2001}, language = {en} } @article{Fischer2001, author = {Fischer, Markus}, title = {Landscape dynamics can accelerate metapopulation extinction}, year = {2001}, language = {en} } @article{Hark2001, author = {Hark, Sabine}, title = {Women's studies in germany and its queer discontents}, year = {2001}, language = {en} } @article{Hark2001, author = {Hark, Sabine}, title = {Disputed territory : feminist studies in Germany and its queer discontents}, year = {2001}, language = {en} } @article{Schoeler2001, author = {Sch{\"o}ler, Klaus}, title = {Regional Market Areas at the EU Border}, isbn = {3-7908-1344-3}, year = {2001}, language = {en} } @article{Gzik2001, author = {Gzik, Axel}, title = {Uptake, transport and effects of heavy metals in higher plants}, year = {2001}, language = {en} } @article{Groezinger2001, author = {Gr{\"o}zinger, Elvira}, title = {A wish to stop beeing a victim}, issn = {1087-9404}, year = {2001}, language = {en} } @article{GowinSaparinKurths2001, author = {Gowin, W. and Saparin, Peter and Kurths, J{\"u}rgen}, title = {Bone architecture quantification: Measures of complexity compared to failure lead results}, year = {2001}, language = {en} } @article{GowinSaparinKurthsetal.2001, author = {Gowin, W. and Saparin, Peter and Kurths, J{\"u}rgen and Felsenberg, D.}, title = {Bone Architecture assessment with Measures of Complexity}, year = {2001}, language = {en} } @article{ZoellerHainzlKurths2001, author = {Z{\"o}ller, Gert and Hainzl, Sebastian and Kurths, J{\"u}rgen}, title = {Observation of growing correlation length as an indicator for critical point behavior prior to large earthquakes}, year = {2001}, language = {en} } @article{HassanKurths2001, author = {Hassan, M. K. and Kurths, J{\"u}rgen}, title = {Competitive random sequential adsorption of point and fixed-sized particles: analytical results}, year = {2001}, language = {en} } @article{HassanKurths2001, author = {Hassan, M. K. and Kurths, J{\"u}rgen}, title = {Transition from random to ordered fractals in fragmentation of particles in an open system}, year = {2001}, language = {en} } @article{ZhouKurthsHu2001, author = {Zhou, Changsong and Kurths, J{\"u}rgen and Hu, B.}, title = {Array-enhanced coherence resonance: Nontrivial effects of heterogeneity and spatial independence of noise}, year = {2001}, language = {en} } @article{EisertBriegel2001, author = {Eisert, Jens and Briegel, Hans J.}, title = {Quantification of Multi-Particle Entanglement}, year = {2001}, language = {en} } @article{RitschelMahapatraZuelicke2001, author = {Ritschel, Thomas and Mahapatra, Susanta and Z{\"u}licke, Lutz}, title = {Quasiclassical dynamics of proton scattering by N2 on an improved ab initio potential energy surface}, year = {2001}, abstract = {An improved analytical representation of the ground electronic potential energy surface (PES) of the (H+, N2) system is generated using the ab initio data reported in our earlier work. The new analytical PES function describes adequately the global behavior and in particular the angular dependence of the interaction as well as the long-range part so that it is amenable to scattering studies. We investigate the elastic and inelastic H+-N2 scattering dynamics on this PES by the quasiclassical trajectory method for center-of-mass collision energies in the range 29-144 eV. The trajectory results thus obtained are compared with the available experimental findings and with recent quantum-mechanical (vibrational close-coupling rotational infinite-order sudden) results. Despite some differences, the experimental data are well reproduced by the present calculations.}, language = {en} } @article{PecherSchirrmannKaiseretal.2001, author = {Pecher, Gabriele and Schirrmann, Thomas and Kaiser, Lothar and Schenk, J{\"o}rg A.}, title = {Efficient cryopreservation of dendritic cells transfected with cDNA of a tumour antigen for clinical application}, year = {2001}, abstract = {Dendritic cells (DCs) are the most potent antigen-presenting cells of the immune system and are currently being investigated in clinical applications as cancer vaccines. An efficient cryopreservation method would greatly contribute to their use in clinical trials. We have established a method for freezing of DCs derived from peripheral blood mononuclear cells using the plasma expander Gelifundol. This enabled us to reduce the concentration of the toxic DMSO to 5\%. The method could be performed without the addition of fetal calf serum or any other serum. After freezing, the viability of the DCs was 90\%. The cells exhibited all the phenotypic characteristics (CD11c+, HLA-DR+, CD80+, CD83+, CD86+) of DCs, as tested by flow cytometry. Cells transfected with cDNA for the tumour antigen mucin expressed this protein on their surfaces in the same manner as before freezing. The stimulating capacity of a mixed lymphocyte culture was also preserved. These findings offer an efficient method for the cryopreservation of DCs for use in clinical trials.}, language = {en} } @article{KlemzKubinaOstermeyeretal.2001, author = {Klemz, Guido and Kubina, P. and Ostermeyer, Martin and Menzel, Ralf}, title = {Diode pumped high power TEM_00 Nd:YAG rod laser with birefringence compensation}, year = {2001}, language = {en} } @article{Kuehling2001, author = {K{\"u}hling, Matthias}, title = {A selection of taxonomic indicator groups for ecological evaluation}, year = {2001}, language = {en} } @article{KuehlingBukowskyKraudelt2001, author = {K{\"u}hling, Matthias and Bukowsky, Heinz and Kraudelt, Heide}, title = {Heavy metal contents of chicken and red toads}, year = {2001}, language = {en} } @article{O'BrienZotovLawetal.2001, author = {O'Brien, Patrick J. and Zotov, Nikolay and Law, Robin and Khan, M. Azam and Jan, M. Q.}, title = {Coesite in Himalayan eclogite and implications for models of India-Asia collision}, issn = {0091-7613}, year = {2001}, language = {en} } @article{CookeO'Brien2001, author = {Cooke, R. A. and O'Brien, Patrick J.}, title = {Resolving the relationship between high P-T rocks and gneisses in collisional terranes : an example from the Gf{\"o}hl gneiss-granulite association in the Moldanubian Zone, Austria}, year = {2001}, language = {en} }