@phdthesis{Grimbs2009, author = {Grimbs, Sergio}, title = {Towards structure and dynamics of metabolic networks}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32397}, school = {Universit{\"a}t Potsdam}, year = {2009}, abstract = {This work presents mathematical and computational approaches to cover various aspects of metabolic network modelling, especially regarding the limited availability of detailed kinetic knowledge on reaction rates. It is shown that precise mathematical formulations of problems are needed i) to find appropriate and, if possible, efficient algorithms to solve them, and ii) to determine the quality of the found approximate solutions. Furthermore, some means are introduced to gain insights on dynamic properties of metabolic networks either directly from the network structure or by additionally incorporating steady-state information. Finally, an approach to identify key reactions in a metabolic networks is introduced, which helps to develop simple yet useful kinetic models. The rise of novel techniques renders genome sequencing increasingly fast and cheap. In the near future, this will allow to analyze biological networks not only for species but also for individuals. Hence, automatic reconstruction of metabolic networks provides itself as a means for evaluating this huge amount of experimental data. A mathematical formulation as an optimization problem is presented, taking into account existing knowledge and experimental data as well as the probabilistic predictions of various bioinformatical methods. The reconstructed networks are optimized for having large connected components of high accuracy, hence avoiding fragmentation into small isolated subnetworks. The usefulness of this formalism is exemplified on the reconstruction of the sucrose biosynthesis pathway in Chlamydomonas reinhardtii. The problem is shown to be computationally demanding and therefore necessitates efficient approximation algorithms. The problem of minimal nutrient requirements for genome-scale metabolic networks is analyzed. Given a metabolic network and a set of target metabolites, the inverse scope problem has as it objective determining a minimal set of metabolites that have to be provided in order to produce the target metabolites. These target metabolites might stem from experimental measurements and therefore are known to be produced by the metabolic network under study, or are given as the desired end-products of a biotechological application. The inverse scope problem is shown to be computationally hard to solve. However, I assume that the complexity strongly depends on the number of directed cycles within the metabolic network. This might guide the development of efficient approximation algorithms. Assuming mass-action kinetics, chemical reaction network theory (CRNT) allows for eliciting conclusions about multistability directly from the structure of metabolic networks. Although CRNT is based on mass-action kinetics originally, it is shown how to incorporate further reaction schemes by emulating molecular enzyme mechanisms. CRNT is used to compare several models of the Calvin cycle, which differ in size and level of abstraction. Definite results are obtained for small models, but the available set of theorems and algorithms provided by CRNT can not be applied to larger models due to the computational limitations of the currently available implementations of the provided algorithms. Given the stoichiometry of a metabolic network together with steady-state fluxes and concentrations, structural kinetic modelling allows to analyze the dynamic behavior of the metabolic network, even if the explicit rate equations are not known. In particular, this sampling approach is used to study the stabilizing effects of allosteric regulation in a model of human erythrocytes. Furthermore, the reactions of that model can be ranked according to their impact on stability of the steady state. The most important reactions in that respect are identified as hexokinase, phosphofructokinase and pyruvate kinase, which are known to be highly regulated and almost irreversible. Kinetic modelling approaches using standard rate equations are compared and evaluated against reference models for erythrocytes and hepatocytes. The results from this simplified kinetic models can simulate acceptably the temporal behavior for small changes around a given steady state, but fail to capture important characteristics for larger changes. The aforementioned approach to rank reactions according to their influence on stability is used to identify a small number of key reactions. These reactions are modelled in detail, including knowledge about allosteric regulation, while all other reactions were still described by simplified reaction rates. These so-called hybrid models can capture the characteristics of the reference models significantly better than the simplified models alone. The resulting hybrid models might serve as a good starting point for kinetic modelling of genome-scale metabolic networks, as they provide reasonable results in the absence of experimental data, regarding, for instance, allosteric regulations, for a vast majority of enzymatic reactions.}, language = {en} } @phdthesis{Michalk2009, author = {Michalk, Daniel M.}, title = {An appraisal of a new method for the full-vector reconstruction of the Earth's magnetic field - applied to volcanic rocks from Mexico}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-31868}, school = {Universit{\"a}t Potsdam}, year = {2009}, abstract = {Das Magnetfeld der Erde wird durch Konvektionsstr{\"o}mungen im elektrisch leitf{\"a}higen, fl{\"u}ssigen eisenreichen {\"a}ußeren Erdkern erzeugt. Eine drastische Auspr{\"a}gung der dynamischen Prozesse im {\"a}ußeren Erdkern sind sowohl Polarit{\"a}tswechsel {\"u}ber geologische Zeitr{\"a}ume, als auch geomagnetische Feldexkursionen (kurze Umpolungen). Letztere sind in geologischen Archiven h{\"a}ufig unzureichend dokumentiert. F{\"u}r ein verbessertes Verst{\"a}ndnis {\"u}ber die Entwicklung des Erdmagnetfeldes in geologischer Vergangenheit ben{\"o}tigen wir Informationen {\"u}ber die Geometrie des gesamten Vektorfeldes, wof{\"u}r neben der Bestimmung der Feldrichtungen auch die Bestimmung der absoluten Pal{\"a}ointensit{\"a}t und des Alters notwendig ist. Insbesondere Vulkanite bieten die M{\"o}glichkeit, Daten {\"u}ber die Richtung und vor allem auch die Intensit{\"a}t des Erdmagnetfeldes zur Zeit ihrer Platznahme zu gewinnen. Bisweilen ist eine genaue Charakterisierung der Entwicklung des Erdmagnetfeldes in Zeit und Raum schwer m{\"o}glich, was sich in erster Linie auf den generellen Mangel an Pal{\"a}ointensit{\"a}tsdaten zur{\"u}ckf{\"u}hren l{\"a}sst. Ein Grund hierf{\"u}r ist, dass die meisten Methoden zur absoluten Pal{\"a}ointensit{\"a}tsbestimmung, auf Modifikationen der Thellier Methode basieren, welche nur auf magnetische Minerale im Einbereichs-Dom{\"a}nenzustand anwendbar ist und zudem hohe Ausschussraten liefert. Eine alternative Methode zur Bestimmung der absoluten Pal{\"a}ointensit{\"a}t ist die k{\"u}rzlich entwickelte „multispecimen parallel differential pTRM" (MS) Methode, welche im Vergleich zur Thellier Methode den Vorteil hat, dass sie theoretisch unabh{\"a}ngig ist vom Dom{\"a}nenzustand der magnetischen Minerale und somit auf alle Vulkanite anwendbar ist. Ein Schwerpunkt dieser Arbeit lag darauf, neue Informationen {\"u}ber das Auftreten und gegebenfalls die globale G{\"u}ltigkeit von geomagnetischen Feldexkursionen zu gewinnen. Hierf{\"u}r wurden etwa 75 Lavafl{\"u}sse des Transmexikanischen Vulkang{\"u}rtels f{\"u}r pal{\"a}omagnetische Studien beprobt. Eine Korrelation der mittleren Pal{\"a}orichtungen von 56 mexikanischen Laven mit einer um Feldexkursionen erg{\"a}nzten geomagnetischen Polarit{\"a}tszeitskala, lieferte Hinweise auf 4 Exkursionen. Ein bedeutendes Ergebnis dieser Arbeit sind ann{\"a}hrend komplett inversen Richtungen zweier Laven der Brunhes Chron. Dies gibt einen Hinweis darauf, dass diese Exkursionen kurze Zeitintervalle inverser Polarit{\"a}t mit globaler G{\"u}ltigkeit repr{\"a}sentieren k{\"o}nnten. Ein weiterer Schwerpunkt der vorliegenden Arbeit war, die neue MS Methode auf ihre Anwendbarkeit und Genauigkeit hin zu testen. Hierf{\"u}r wurden Pal{\"a}ointensit{\"a}tsexperimente an 11 historischen Laven aus Mexiko und Island durchgef{\"u}hrt. Ein Vergleich der Pal{\"a}ointensit{\"a}ten mit Daten von magnetischen Observatorien ergab, dass die MS Methode einen generellen Trend zur {\"U}bersch{\"a}tzung der Pal{\"a}ointensit{\"a}t aufweisst, welcher anhand von komplementierenden gesteinsmagnetischen Daten mit magnetischen Mineralen im Mehrbereichsteilchen-Zustand in Verbindung gebracht werden konnte. Diese Beobachtung liefert demnach einen ersten Beweis daf{\"u}r, dass die MS Methode m{\"o}glicherweise nicht wie urspr{\"u}nglich angenommen unabh{\"a}ngig vom Dom{\"a}nenzustand der Tr{\"a}germinerale ist. Im weiteren wurde eine Komplementierung der Richtungsdaten mexikanischer Laven durch absolute Pal{\"a}ointensit{\"a}tsbestimmungen angestrebt. Hierf{\"u}r wurde die MS Methode herangezogen und zum ersten Mal in großem Umfang auf Vulkanite mit Altern von bis zu 3,5 Millionen Jahre angewendet. Ein Vergleich mit Rekonstruktionen des Dipol-Momentes, welche auf den Daten der gegenw{\"a}rtigen globalen Pal{\"a}ointensit{\"a}tsdatanbasis basieren, ergaben, dass diese MS Daten mit hoher statistischer Wahrscheinlichkeit im Mittel etwa 30\% h{\"o}her sind. Die generell zu hohen Pal{\"a}onintensit{\"a}ten nach der MS Methode bekr{\"a}ftigen daher die Ergebnisse von historischen Laven dieser Arbeit, sowie anderer experimenteller Studien an synthetischen Proben, bei denen {\"U}bersch{\"a}tzungen von MS Pal{\"a}ointensit{\"a}ten von bis zu 30\% festgestellt wurden. Der Process, aus dem diese {\"U}bersch{\"a}tzung der Pal{\"a}ointensit{\"a}t resultiert ist eine Asymetrie des Entmagnetisierungs- und Remagnetisierungsprozesses heisst, dass ein effektives Entmagnetisieren w{\"a}hrend der Remagnetisierung im angelegten Laborfeld erfolgt. Diese Asymetrie scheint besonders bei pseudo-Einbereichsteilchen ausgepr{\"a}gt zu sein. Es wird allerdings davon ausgegangen, dass diese {\"U}bersch{\"a}tzung nicht gr{\"o}ßer ist, als was man bei einem Thellier Experiment an Proben mit {\"a}hnlicher magnetischer Korngr{\"o}ße erwarten w{\"u}rde.}, language = {en} } @phdthesis{Zamagni2009, author = {Zamagni, Jessica}, title = {Responses of a shallow-water ecosystem to the early Paleogene greenhouse environmental conditions : evolution of Larger Foraminifera and coral communities from the Northern Tethys}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-31853}, school = {Universit{\"a}t Potsdam}, year = {2009}, abstract = {Modern anthropogenic forcing of atmospheric chemistry poses the question of how the Earth System will respond as thousands of gigatons of greenhouse gas are rapidly added to the atmosphere. A similar, albeit nonanthropogenic, situation occurred during the early Paleogene, when catastrophic release of carbon to the atmosphere triggered abrupt increase in global temperatures. The best documented of these events is the Paleocene-Eocene Thermal Maximum (PETM, ~55 Ma) when the magnitude of carbon addition to the oceans and atmosphere was similar to those expected for the future. This event initiated global warming, changes in hydrological cycles, biotic extinction and migrations. A recently proposed hypothesis concerning changes in marine ecosystems suggests that this global warming strongly influenced the shallow-water biosphere, triggering extinctions and turnover in the Larger Foraminifera (LF) community and the demise of corals. The successions from the Adriatic Carbonate Platform (SW Slovenia) represent an ideal location to test the hypothesis of a possible causal link between the PETM and evolution of shallow-water organisms because they record continuous sedimentation from the Late Paleocene to the Early Eocene and are characterized by a rich biota, especially LF, fundamental for detailed biostratigraphic studies. In order to reconstruct paleoenvironmental conditions during deposition, I focused on sedimentological analysis and paleoecological study of benthic assemblages. During the Late Paleocene-earliest Eocene, sedimentation occurred on a shallow-water carbonate ramp system characterized by enhanced nutrient levels. LF represent the common constituent of the benthic assemblages that thrived in this setting throughout the Late Paleocene to the Early Eocene. With detailed biostratigraphic and chemostratigraphic analyses documenting the most complete record to date available for the PETM event in a shallow-water marine environment, I correlated chemostratigraphically for the first time the evolution of LF with the δ¹³C curves. This correlation demonstrated that no major turnover in the LF communities occurred synchronous with the PETM; thus the evolution of LF was mainly controlled by endogenous biotic forces. The study of Late Thanetian metric-sized microbialite-coral mounds which developed in the middle part of the ramp, documented the first Cenozoic occurrence of microbially-cemented mounds. The development of these mounds, with temporary dominance of microbial communities over corals, suggest environmentally-triggered "phase shifts" related to frequent fluctuations of nutrient/turbidity levels during recurrent wet phases which preceding the extreme greenhouse conditions of the PETM. The paleoecological study of the coral community in the microbialites-coral mounds, the study of corals from Early Eocene platform from SW France, and a critical, extensive literature research of Late Paleocene - Early Eocene coral occurrences from the Tethys, the Atlantic, the Caribbean realms suggested that these corals types, even if not forming extensive reefs, are common in the biofacies as small isolated colonies, piles of rubble or small patch-reefs. These corals might have developed 'alternative' life strategies to cope with harsh conditions (high/fluctuating nutrients/turbidity, extreme temperatures, perturbation of aragonite saturation state) during the greenhouse times of the early Paleogene, representing a good fossil analogue to modern corals thriving close to their thresholds for survival. These results demonstrate the complexity of the biological responses to extreme conditions, not only in terms of temperature but also nutrient supply, physical disturbance and their temporal variability and oscillating character.}, language = {en} } @phdthesis{ElSaadany2009, author = {El-Saadany, Mohamed Abdel Meged Marawan}, title = {Protective effect of dietary antioxidants and plant extracts on acute inflammation and hepatotoxicity in vitro}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-31585}, school = {Universit{\"a}t Potsdam}, year = {2009}, abstract = {Dietary antioxidants are believed to play an important role in the prevention and treatment of a variety of diseases associated with oxidative stress. Although there is a wide range of dietary antioxidants, the bulk of the research to date has been focused on the nutrient antioxidants vitamin C, E, and carotenoids. Certain relatively uncommon antioxidants such as lipoic acid (LA), and phenolic compounds such as (-)-epicatechin (EC), (-)-epigallocatechin (EGC), (-)-epicatechin gallate (ECG), and (-)-epigallocatechin gallate (EGCG), have not been extensively investigated although they may exert greater antioxidant potency than that of carotenoids and vitamins. Extracts from selected plants and plant byproducts may represent rich sources for one or more of such antioxidants and therefore exhibit higher effects than a single antioxidant due to the synergistic effects produced between such antioxidants. However, in the last decade a number of epidemiological, animal and in vitro studies have suggested a protective and therapeutic potency of these antioxidants in a broad range of diseases such as cancer, diabetes, atherosclerosis, cataract and acute and chronic neurological disorders. Inflammation, the response of the host toward any infection or injury, plays a central role in the development of many chronic diseases. Several evidences demonstrated the rise of different types of cancer from sites of inflammation. This suggests that active oxygen species and some cytokines generated in the inflamed tissues can cause injury to DNA and ultimately lead to carcinogenesis. Diethylnitrosamine (DEN) is one of the most important environmental carcinogens, present in a variety of foods, alcoholic beverages, tobacco smoke and it can be synthesized endogenously. In addition to the liver it can induce carcinogenesis in other organs like kidney, trachea, lung, esophagus, fore stomach, and nasal cavity. Several epidemiological and laboratory studies indicate that nitroso compounds including DEN may induce hyperplasia and chronic inflammation which is closely associated with the development of hepatocellular carcinoma. Despite increasing evidence on the potential of antioxidants in modulating the etiology of chronic diseases, little is known about their role in inflammation and acute phase response (APR). Therefore the aim of the present work was to study the protective effect of water and solvent extracts of eight plant and plant byproducts including green tea, artichoke, spinach, broccoli, onion and eggplant, orange and potato peels as well as eight antioxidants agents including EC, EGC, ECG, EGCG, ascorbic acid (AA), acetylcysteine (NAC), α-LA, and alpha-tocopherol (α-TOC) toward acute inflammation induced by interleukin-6 (IL-6) and hepatotoxicity induced by DEN in vitro. The negative acute phase proteins (APP), transthyretin (TTR) and retinol-binding protein (RBP) were used as inflammatory biomarkers analyzed by ELISA, whereas neutral red assay was used for evaluating the cytotoxicity. All experiments were performed in vitro using human hepatocarcinoma cell line (HepG2). Additionally the antioxidant activity was measured by TEAC and FRAP assays, phenolic content was measured by Folin-Ciocalteu and characterized by HPLC. Moreover, the microheterogeneity of TTR was detected using immunoprecipitation assay combined with SELDI-TOF MS. Results of present study showed that HepG2 cells provide a simple, sensitive in vitro system for studying the regulation of the negative APP, TTR and RBP under free and inflammatory condition. IL-6, a potent proinflammatory cytokine, in a concentration of 25 ng/ml was able to reduce TTR and RBP secretion by approximately 50-60\% after 24h of incubation. With exception of broccoli and water extract of onion which showed pro-inflammatory effects in this study, all other plant extracts, at specific concentrations, were able to elevate TTR secretion in normal condition and even under treatment of IL-6 where the effect was quite lower. Green tea followed by artichoke and potato peel exhibited the highest elevation in TTR concentration which reached 1.1 and 2.5 folds of control in presence and absences of IL-6 respectively. In general Plant extracts were ordered according their anti-inflammatory potency as following: in water extracts; green tea > artichoke > potato peel > orange peel > spinach > eggplant peel, where in solvent extracts; green tea > artichoke > potato peel > spinach > eggplant peel > onion > orange peel. The antiinflammatory effect of water extracts of green tea, artichoke and orange peel were significantly higher than their corresponding solvent extracts whereas water extracts of eggplant-, potato peels and spinach showed lower effect than their solvent extracts. On the other hand α-LA followed by EGCG and ECG exhibited the highest elevation in TTR concentration compared to other antioxidants. The relation between the anti-inflammatory potential and antioxidants activity and phenolic content for the investigated substances was generally weak. This may suggest the involvement of other mechanisms than antioxidants properties for the observed effect. TTR secreted by HepG2 cells has a molecular structure quite similar to the purified standard and serum TTR in which all the three main variants are contained including native, S-cystinylated and Sglutathionylated TTR. Interestingly, a variant with molecular mass of 13453.8 + 8.3 Da has been detected only in TTR secreted by HepG2. Among all investigated antioxidants and plant extracts, six substances were able to elevate the native preferable TTR variant. The potency of these substances can be ordered as following α-LA > NAC > onion > AA > EGCG > green tea. A weak correlation between elevation on TTR and shifting to the native form was observed. Similar weak correlation has also been observed between antioxidants activity and elevation in native TTR. Although DEN was able to induce cell death in a concentration dependent manner, it requires considerably higher concentrations for its effects especially after 24h. This may be attributed to a lack in cytochrome P450 enzymes produced by HepG2. At selected concentrations some antioxidants and plant extracts significantly attenuate DEN cytotoxicity as following: spinach > α-LA > artichoke > orange peel > eggplant peel > α-TOC > onion > AA. Contrary all other substances especially green tea, broccoli, potato peel, and ECG stimulate DEN toxicity. In conclusion, this study demonstrated that selected antioxidants and plant extracts may attenuate the inflammatory process, not only by their antioxidants potency but also by other mechanisms which remain unclear. They may also play a vital role on stabilizing the tetramic structure of TTR and thereby prevent amyloidosis diseases. Lipoic acid represents in this study unique function against inflammation and hepatotoxicity. Despite the protective effect demonstrated by investigated substances, attention should also be given to the pro-oxidant and potential cytotoxic effects produced at higher concentrations.}, language = {en} } @article{GrovePutnam2009, author = {Grove, Kyle Wade and Putnam, Mike}, title = {Deriving pairedness in vP structure}, series = {Linguistics in Potsdam}, journal = {Linguistics in Potsdam}, number = {28}, issn = {1616-7392}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32284}, pages = {187 -- 210}, year = {2009}, abstract = {Minimalist accounts lack a natural theory of markedness, whereas Optimality-Theoretical accounts fundamentally encode markedness. We think the duality of interfaces assumed in Minimalism is a step towards explaining pairedness behavior, where a given language exhibits a marked/ unmarked pair of items occupying the same niche. We argue that while Minimalism articulates the derivational aspect of language, and underlies grammaticality, an Optimality Theoretic articulation of PF and LF is conceptually natural and explains pairedness behavior. We adopt this 'hybrid' account, first, to explain the existence of marked (often termed 'reflexive') and unmarked anticausatives in German, recently studied in depth by Sch¨afer [2007].}, language = {en} } @article{Komen2009, author = {Komen, Erwin R.}, title = {Branching constraints}, series = {Linguistics in Potsdam}, journal = {Linguistics in Potsdam}, number = {28}, issn = {1616-7392}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32273}, pages = {157 -- 186}, year = {2009}, abstract = {Rejecting approaches with a directionality parameter, mainstream minimalism has adopted the notion of strict (or unidirectional) branching. Within optimality theory however, constraints have recently been proposed that presuppose that the branching direction scheme is language specific. I show that a syntactic analysis of Chechen word order and relative clauses using strict branching and movement triggered by feature checking seems very unlikely, whereas a directionality approach works well. I argue in favor of a mixed directionality approach for Chechen, where the branching direction scheme depends on the phrase type. This observation leads to the introduction of context variants of existing markedness constraints, in order to describe the branching processes in terms of optimality theory. The paper discusses how and where the optimality theory selection of the branching directions can be implemented within a minimalist derivation.}, language = {en} } @article{Nunes2009, author = {Nunes, Jairo}, title = {Preposition insertion in the mapping from spell-out to PF}, series = {Linguistics in Potsdam}, journal = {Linguistics in Potsdam}, number = {28}, issn = {1616-7392}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32262}, pages = {133 -- 156}, year = {2009}, abstract = {This paper discusses three case studies on the realization of spurious prepositions and argues that they illustrate a general interaction of convergence requirements of the morphological component with an economy condition that enforces faithfulness between the lexical items present in the numeration and the lexical items present in the PF output.}, language = {en} } @article{Salzmann2009, author = {Salzmann, Martin}, title = {Variation in resumption requires violable constraints}, series = {Linguistics in Potsdam}, journal = {Linguistics in Potsdam}, number = {28}, issn = {1616-7392}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32251}, pages = {99 -- 132}, year = {2009}, abstract = {Variation in dative resumption among and within Alemannic varieties of German strongly favors an Evaluator component that makes use of optimality-theoretic evaluation rather than filters as in the Minimalist Program (MP). At the same time, the variation is restricted to realizational requirements. This supports a model of syntax like the Derivations and Evaluations framework (Broekhuis 2008) that combines a restrictive MP-style Generator with an Evaluator that includes ranked violable (interface) constraints.}, language = {en} } @article{Schaden2009, author = {Schaden, Gerhard}, title = {Say hello to markedness}, series = {Linguistics in Potsdam}, journal = {Linguistics in Potsdam}, number = {28}, issn = {1616-7392}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32247}, pages = {73 -- 97}, year = {2009}, abstract = {In this paper, it will be shown that Bi-directional Optimality Theory (BOT) runs into problems of undergeneration when confronted with a certain class of partial-blocking phenomena. The empirical problem used to illustrate this is the cross-linguistic variation of one-step past-referring tenses. It will be argued that the well-known 'present perfect puzzle' is a sub-problem of it. The solution to the cross-linguistic variation of these tenses involves blocking of the marked tense. The relevant notion of 'markedness', while underivable synchronically, is argued to be linked to diachronic learning processes similar to those investigated by Benz (2006).}, language = {en} } @article{Woolford2009, author = {Woolford, Ellen}, title = {Aspect splits and parasitic marking}, series = {Linguistics in Potsdam}, journal = {Linguistics in Potsdam}, number = {28}, issn = {1616-7392}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32236}, pages = {39 -- 72}, year = {2009}, abstract = {Aspect splits can affect agreement, Case, and even preposition insertion. This paper discusses the functional 'why' and the theoretical 'how' of aspect splits. Aspect splits are an economical way to mark aspect by preserving or suppressing some independent element in one aspect. In formal terms, they are produced in the same way as coda conditions in phonology, with positional/contextual faithfulness.This approach captures the additive effects of cross-cutting splits. Aspect splits are analyzed here from Hindi, Nepali, Yucatec Maya, Chontal, and Palauan.}, language = {en} } @article{Zeijlstra2009, author = {Zeijlstra, Hedde}, title = {Hard and soft conditions on the faculty of language}, series = {Linguistics in Potsdam}, journal = {Linguistics in Potsdam}, number = {28}, issn = {1616-7392}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32221}, pages = {9 -- 38}, year = {2009}, abstract = {In this paper I argue that both parametric variation and the alleged differences between languages in terms of their internal complexity straightforwardly follow from the Strongest Minimalist Thesis that takes the Faculty of Language (FL) to be an optimal solution to conditions that neighboring mental modules impose on it. In this paper I argue that hard conditions like legibility at the linguistic interfaces invoke simplicity metrices that, given that they stem from different mental modules, are not harmonious. I argue that widely attested expression strategies, such as agreement or movement, are a direct result of conflicting simplicity metrices, and that UG, perceived as a toolbox that shapes natural language, can be taken to consist of a limited number of markings strategies, all resulting from conflicting simplicity metrices. As such, the contents of UG follow from simplicity requirements, and therefore no longer necessitate linguistic principles, valued or unvalued, to be innately present. Finally, I show that the SMT does not require that languages themselves have to be optimal in connecting sound to meaning.}, language = {en} } @article{Clausen2009, author = {Clausen, Bernd}, title = {„Vielfalt" in musikbezogenen Diskursen}, series = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, journal = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, number = {2}, issn = {1861-8529}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-31950}, pages = {124 -- 134}, year = {2009}, abstract = {Inhalt: 1. Vorbemerkung 2. Was Vielfalt nicht heißt 3. Was meint denn nun musikalische Vielfalt? 4. Schlussbemerkung}, language = {de} } @article{Jank2009, author = {Jank, Birgit}, title = {Zur notwendigen F{\"o}rderung interkultureller Kompetenz an deutschen Hochschulen in den Bereichen der Musik}, series = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, journal = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, number = {2}, issn = {2196-5080}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32188}, pages = {121 -- 123}, year = {2009}, abstract = {Inhalt: 1. {\"O}ffnung der Hochschulen f{\"u}r einen kulturellen Dialog 2. F{\"o}rderung einer interkulturellen Kompetenz in allen Bereichen des Studiums 3. Forschung zu interkulturellen Fragestellungen initiieren 4. Sprachf{\"a}higkeit f{\"o}rdern}, language = {de} } @article{Jank2009, author = {Jank, Birgit}, title = {J{\"u}dische Musik als Gegenstand interkultureller Musikp{\"a}dagogik}, series = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, journal = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, number = {2}, issn = {1861-8529}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32177}, pages = {119 -- 120}, year = {2009}, language = {de} } @article{Jank2009, author = {Jank, Birgit}, title = {Zeitgeschichtliche Dimensionen musikalischen Lernens und musikp{\"a}dagogischer Forschung}, series = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, journal = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, number = {2}, issn = {2196-5080}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32165}, pages = {108 -- 118}, year = {2009}, abstract = {Inhalt: 1. Einf{\"u}hrung 2. Einige Bruchst{\"u}cke aus den Arbeitsergebnissen zur Forschung DDR-Musikerziehung und zum Musiklernen in der DDR 3. Ausgew{\"a}hlte Diskussionspunkte und Perspektiven im zeitgeschichtlichen Forschungsfeld DDR-Musikerziehung 3.1 Was ist Zeitgeschichte im Kontext musikp{\"a}dagogischer Forschung? 3.2 Welche motivationalen Zug{\"a}nge zur Erforschung der DDR-Musikp{\"a}dagogik lassen sich finden? 3.3 Kann die wissenschaftliche Auseinandersetzung mit der DDR-Musikp{\"a}dagogik als Modellfall gelten? 3.4 Welcher Sachstand ist zur Erforschung der DDR-Musikp{\"a}dagogik zu bilanzieren? 3.5 Welche Forschungsdesiderata konnten festgestellt werden?}, language = {de} } @article{OliveiraPinto2009, author = {Oliveira Pinto, Tiago de}, title = {Kulturen im Karneval und 'Karneval der Kulturen'}, series = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, journal = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, number = {2}, issn = {1861-8529}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32152}, pages = {103 -- 107}, year = {2009}, language = {de} } @article{RodriguezQuilesyGarcia2009, author = {Rodr{\´i}guez-Quiles y Garc{\´i}a, Jos{\´e} A.}, title = {Haben die Deutschen Interesse am Flamenco?}, series = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, journal = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, number = {2}, issn = {1861-8529}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32147}, pages = {76 -- 95}, year = {2009}, abstract = {Are the Germans interested in flamenco nowadays? If so they are, then how can a type of art that is so different from both German cultured and popular music be represented in the culture of that country? Possible answers to this and other questions on the still romantic image of flamenco held in Central Europe will be provided by the analysis of the flamenco being offered at German universities, festivals, private dance schools, publishing houses and websites.}, language = {de} } @article{RodriguezQuilesyGarcia2009, author = {Rodr{\´i}guez-Quiles y Garc{\´i}a, Jos{\´e} A.}, title = {?'Est{\´a}n los alemanes interesados por el flamenco?}, series = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, journal = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, number = {2}, issn = {1861-8529}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32133}, pages = {55 -- 75}, year = {2009}, abstract = {Are the Germans interested in flamenco nowadays? If so they are, then how can a type of art that is so different from both German cultured and popular music be represented in the culture of that country? Possible answers to this and other questions on the still romantic image of flamenco held in Central Europe, will be provided by the analysis of the flamenco being offered at German universities, festivals, private dance schools, publishing houses and websites.}, language = {mul} } @article{RodriguezQuilesyGarcia2009, author = {Rodr{\´i}guez-Quiles y Garc{\´i}a, Jos{\´e} A.}, title = {Spain : current planning for music education}, series = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, journal = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, number = {2}, issn = {1861-8529}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32124}, pages = {34 -- 54}, year = {2009}, abstract = {Content: 1. Introduction 2. Music in the curriculum of The Educaci{\´o}n Obligatoria 2.1 Music in Educaci{\´o}n Primaria - Listening and Comprehension - Music Making - Rational Analysis (Musical Notation) 2.2. Music in Educaci{\´o}n Secundaria Obligatoria (E.S.O. Compulsory Secondary education) and Bachillerato (Pre-University Education) 3. Music in the Spanish Non-Compulsory Education 3.1. Elementary and Medium Levels 3.2. The "Title of Higher Music Education" 4. The new certificate of "Didactic Specialization" 5. Concluding remarks}, language = {en} } @article{RodriguezQuilesyGarcia2009, author = {Rodr{\´i}guez-Quiles y Garc{\´i}a, Jos{\´e} A.}, title = {Vergleichende Musikp{\"a}dagogik am Beispiel der L{\"a}nder Spanien und Deutschland}, series = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, journal = {Potsdamer Schriftenreihe zur Musikp{\"a}dagogik}, number = {2}, issn = {1861-8529}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-32116}, pages = {26 -- 33}, year = {2009}, abstract = {Inhalt: 1. Musikp{\"a}dagogik in Spanien: ein neues Forschungsgebiet 2. Konzeptionelle Rahmenbedingungen 3. Aktueller Stand und geplante Fortf{\"u}hrung des Forschungsprojektes}, language = {de} }