@article{ParshinaLaurinavichyuteSekerina2021, author = {Parshina, Olga and Laurinavichyute, Anna and Sekerina, Irina A.}, title = {Eye-movement benchmarks in heritage language reading}, series = {Bilingualism : language and cognition}, volume = {24}, journal = {Bilingualism : language and cognition}, number = {1}, publisher = {Cambridge University Press}, address = {Cambridge}, issn = {1366-7289}, doi = {10.1017/S136672892000019X}, pages = {69 -- 82}, year = {2021}, abstract = {This eye-tracking study establishes basic benchmarks of eye movements during reading in heritage language (HL) by Russian-speaking adults and adolescents of high (n = 21) and low proficiency (n = 27). Heritage speakers (HSs) read sentences in Cyrillic, and their eye movements were compared to those of Russian monolingual skilled adult readers, 8-year-old children and L2 learners. Reading patterns of HSs revealed longer mean fixation durations, lower skipping probabilities, and higher regressive saccade rates than in monolingual adults. High-proficient HSs were more similar to monolingual children, while low-proficient HSs performed on par with L2 learners. Low-proficient HSs differed from high-proficient HSs in exhibiting lower skipping probabilities, higher fixation counts, and larger frequency effects. Taken together, our findings are consistent with the weaker links account of bilingual language processing as well as the divergent attainment theory of HL.}, language = {en} } @article{PalmaMunozRamirezCampilloAzocarGallardoetal.2021, author = {Palma-Mu{\~n}oz, Ignacio and Ram{\´i}rez-Campillo, Rodrigo and Azocar-Gallardo, Jairo and {\´A}lvarez, Cristian and Asadi, Abbas and Moran, Jason and Chaabene, Helmi}, title = {Effects of progressed and nonprogressed volume-based overload plyometric training on components of physical fitness and body composition variables in youth male basketball players}, series = {Journal of strength and conditioning research : the research journal of the NSCA}, volume = {35}, journal = {Journal of strength and conditioning research : the research journal of the NSCA}, number = {6}, publisher = {Lippincott Williams \& Wilkins}, address = {Philadelphia}, issn = {1064-8011}, doi = {10.1519/JSC.0000000000002950}, pages = {1642 -- 1649}, year = {2021}, abstract = {This study examined the effect of 6 weeks of progressed and nonprogressed volume-based overload plyometric training (PT) on components of physical fitness and body composition measures in young male basketball players, compared with an active control group. Subjects were randomly assigned to a progressed PT (PPT, n = 7; age = 14.6 +/- 1.1 years), a non-PPT (NPPT, n = 8, age = 13.8 +/- 2.0 years), or a control group (CG, n = 7, age = 14.0 +/- 2.0 years). Before and after training, body composition measures (muscle mass and fat mass), countermovement jump with arms (CMJA) and countermovement jump without arms (CMJ), horizontal bilateral (HCMJ) and unilateral jump with right leg (RJ) and left leg (LJ), 20-cm drop jump (DJ20), sprint speed (10 m sprint), and change of direction speed (CODS [i.e., T-test]) were tested. Significant effects of time were observed for muscle and fat mass, all jump measures, and CODS (all p < 0.01; d = 0.37-0.83). Significant training group x time interactions were observed for all jump measures (all p < 0.05; d = 0.24-0.41). Post hoc analyses revealed significant pre-post performance improvements for the PPT (RJ and LJ: increment 18.6\%, d = 0.8 and increment 22.7\%, d = 0.9, respectively; HCMJ: increment 16.4\%, d = 0.8; CMJ: increment 22.4\%, d = 0.7; CMJA: increment 23.3\%, d = 0.7; and DJ20: increment 39.7\%, d = 1.1) and for the NPPT group (LJ: increment 14.1\%, d = 0.4; DJ20: increment 32.9\%, d = 0.8) with greater changes after PPT compared with NPPT for all jump measures (all p < 0.05; d = 0.21-0.81). The training efficiency was greater (p < 0.05; d = 0.22) after PPT (0.015\% per jump) compared with NPPT (0.0053\% per-jump). The PPT induced larger performance improvements on measures of physical fitness as compared to NPPT. Therefore, in-season progressive volume-based overload PT in young male basketball players is recommended.}, language = {en} } @article{MatheisKellerKronborgetal.2019, author = {Matheis, Svenja and Keller, Lena and Kronborg, Leonie and Schmitt, Manfred and Preckel, Franzis}, title = {Do stereotypes strike twice?}, series = {Asia-Pacific journal of teacher education}, volume = {48}, journal = {Asia-Pacific journal of teacher education}, number = {2}, publisher = {Routledge Journals, Taylor \& Francis}, address = {Abingdon}, issn = {1469-2945}, doi = {10.1080/1359866X.2019.1576029}, pages = {213 -- 232}, year = {2019}, abstract = {Stereotypes influence teachers' perception of and behaviour towards students, thus shaping students' learning opportunities. The present study investigated how 315 Australian pre-service teachers' stereotypes about giftedness and gender are related to their perception of students' intellectual ability, adjustment, and social-emotional ability, using an experimental vignette approach and controlling for social desirability in pre-service teachers' responses. Repeated-measures ANOVA showed that pre-service teachers associated giftedness with higher intellectual ability, but with less adjustment compared to average-ability students. Furthermore, pre-service teachers perceived male students as less socially and emotionally competent and less adjusted than female students. Additionally, pre-service teachers seemed to perceive female average-ability students' adjustment as most favourable compared to male average-ability students and gifted students. Findings point to discrepancies between actual characteristics of gifted female and male students and stereotypes in teachers' beliefs. Consequences of stereotyping and implications for teacher education are discussed.}, language = {en} } @article{KoesterKayhanLangelohetal.2020, author = {K{\"o}ster, Moritz and Kayhan, Ezgi and Langeloh, Miriam and Hoehl, Stefanie}, title = {Making sense of the world}, series = {Perspectives on Psychological Science}, volume = {15}, journal = {Perspectives on Psychological Science}, number = {3}, publisher = {Sage}, address = {London}, issn = {1745-6916}, doi = {10.1177/1745691619895071}, pages = {562 -- 571}, year = {2020}, abstract = {For human infants, the first years after birth are a period of intense exploration-getting to understand their own competencies in interaction with a complex physical and social environment. In contemporary neuroscience, the predictive-processing framework has been proposed as a general working principle of the human brain, the optimization of predictions about the consequences of one's own actions, and sensory inputs from the environment. However, the predictive-processing framework has rarely been applied to infancy research. We argue that a predictive-processing framework may provide a unifying perspective on several phenomena of infant development and learning that may seem unrelated at first sight. These phenomena include statistical learning principles, infants' motor and proprioceptive learning, and infants' basic understanding of their physical and social environment. We discuss how a predictive-processing perspective can advance the understanding of infants' early learning processes in theory, research, and application.}, language = {en} } @article{PaoliMoroLorenzettietal.2020, author = {Paoli, Antonio and Moro, Tatiana and Lorenzetti, Silvio and Seiler, Jan and L{\"u}thy, Fabian and Gross, Micah and Roggio, Federico and Chaabene, Helmi and Musumeci, Giuseppe}, title = {The "Journal of Functional Morphology and Kinesiology" Journal Club Series}, series = {Journal of Functional Morphology and Kinesiology}, volume = {5}, journal = {Journal of Functional Morphology and Kinesiology}, number = {2}, publisher = {MDPI}, address = {Basel}, issn = {2411-5142}, doi = {10.3390/jfmk5020025}, pages = {1 -- 9}, year = {2020}, abstract = {We are glad to introduce the Second Journal Club of Volume Five, Second Issue. This edition is focused on relevant studies published in the last few years in the field of resistance training, chosen by our Editorial Board members and their colleagues. We hope to stimulate your curiosity in this field and to share with you the passion for the sport, seen also from the scientific point of view. The Editorial Board members wish you an inspiring lecture.}, language = {en} } @article{GhaniSobelZeilingeretal.2021, author = {Ghani, Humaad and Sobel, Edward and Zeilinger, Gerold and Glodny, Johannes and Irum, Irum and Sajid, Muhammad}, title = {Spatio-temporal structural evolution of the Kohat fold and thrust belt of Pakistan}, series = {Journal of structural geology}, volume = {145}, journal = {Journal of structural geology}, publisher = {Elsevier}, address = {Amsterdam [u.a.]}, issn = {0191-8141}, doi = {10.1016/j.jsg.2021.104310}, pages = {16}, year = {2021}, abstract = {The Kohat fold and thrust belt in Pakistan shows a significantly different structural style due to the structural evolution on the double d{\´e}collement compared to the rest of the Subhimalaya. In order to better understand the spatio-temporal structural evolution of the Kohat fold and thrust belt, we combine balanced cross sections with apatite (U?Th-Sm)/He (AHe) and apatite fission track (AFT) dating. The AHe and AFT ages appear to be totally reset, allowing us to date exhumation above structural ramps. The results suggest that deformation began on the frontal Surghar thrust at-15 Ma, predating or coeval with the development of the Main Boundary thrust at-12 Ma. Deformation propagated southward from the Main Boundary thrust on double de?collements between 10 Ma and 2 Ma, resulting in a disharmonic structural style inside the Kohat fold and thrust belt. Thermal modeling of the thermochronologic data suggest that samples inside Kohat fold and thrust belt experienced cooling due to formation of the duplexes; this deformation facilitated tectonic thickening of the wedge and erosion of the Miocene to Pliocene foreland strata. The spatial distribution of AHe and AFT ages in combination with the structural forward model suggest that, in the Kohat fold and thrust belt, the wedge deformed in-sequence as a supercritical wedge (-15-12 Ma), then readjusted by out-sequence deformation (-12-0 Ma) within the Kohat fold and thrust belt into a sub-critical wedge.}, language = {en} } @article{BelaidRabusKrestel2021, author = {Belaid, Mohamed Karim and Rabus, Maximilian and Krestel, Ralf}, title = {CrashNet}, series = {Data mining and knowledge discovery}, volume = {35}, journal = {Data mining and knowledge discovery}, number = {4}, publisher = {Springer}, address = {Dordrecht}, issn = {1384-5810}, doi = {10.1007/s10618-021-00761-9}, pages = {1688 -- 1709}, year = {2021}, abstract = {Destructive car crash tests are an elaborate, time-consuming, and expensive necessity of the automotive development process. Today, finite element method (FEM) simulations are used to reduce costs by simulating car crashes computationally. We propose CrashNet, an encoder-decoder deep neural network architecture that reduces costs further and models specific outcomes of car crashes very accurately. We achieve this by formulating car crash events as time series prediction enriched with a set of scalar features. Traditional sequence-to-sequence models are usually composed of convolutional neural network (CNN) and CNN transpose layers. We propose to concatenate those with an MLP capable of learning how to inject the given scalars into the output time series. In addition, we replace the CNN transpose with 2D CNN transpose layers in order to force the model to process the hidden state of the set of scalars as one time series. The proposed CrashNet model can be trained efficiently and is able to process scalars and time series as input in order to infer the results of crash tests. CrashNet produces results faster and at a lower cost compared to destructive tests and FEM simulations. Moreover, it represents a novel approach in the car safety management domain.}, language = {en} } @article{WachsGamezGuadixWright2022, author = {Wachs, Sebastian and Gamez-Guadix, Manuel and Wright, Michelle F.}, title = {Online hate speech victimization and depressive symptoms among adolescents}, series = {Cyberpsychology, behavior and social networking}, volume = {25}, journal = {Cyberpsychology, behavior and social networking}, number = {7}, publisher = {Liebert}, address = {New Rochelle}, issn = {2152-2715}, doi = {10.1089/cyber.2022.0009}, pages = {416 -- 423}, year = {2022}, abstract = {Online hate speech has become a widespread problem in the daily life of adolescents. Despite growing societal and academic interest in this online risk, not much is known about the relationship between online hate speech victimization (OHSV) and adolescents' mental well-being. In addition, potential factors influencing the magnitude of this relationship remain unclear. To address these gaps in the literature, this study investigated the relationship between OHSV and depressive symptoms and the buffering effects of resilience in this relationship. The sample consists of 1,632 adolescents (49.1\% girls) between 12 and 18 years old (M-age = 13.83, SDage = 1.23), recruited from nine schools across Spain. Self-report questionnaires were administered to assess OHSV, depressive symptoms, and resilience. Regression analyses revealed that OHSV was positively linked to depressive symptoms. In addition, victims of online hate speech were less likely to report depressive symptoms when they reported average or high levels of resilience (i.e., social competence, personal competence, structured style, social resources, and family cohesion) compared with those with low levels of resilience. Our findings highlight the need for the development of intervention programs and the relevance of focusing on internal and external developmental assets to mitigate negative outcomes for victims of online hate speech.}, language = {en} } @article{KrumbholzIshidaBaunachetal.2022, author = {Krumbholz, Julia and Ishida, Keishi and Baunach, Martin and Teikari, Jonna and Rose, Magdalena M. and Sasso, Severin and Hertweck, Christian and Dittmann, Elke}, title = {Deciphering chemical mediators regulating specialized metabolism in a symbiotic cyanobacterium}, series = {Angewandte Chemie : a journal of the Gesellschaft Deutscher Chemiker. International edition}, journal = {Angewandte Chemie : a journal of the Gesellschaft Deutscher Chemiker. International edition}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1433-7851}, doi = {10.1002/anie.202204545}, pages = {10}, year = {2022}, abstract = {Genomes of cyanobacteria feature a variety of cryptic biosynthetic pathways for complex natural products, but the peculiarities limiting the discovery and exploitation of the metabolic dark matter are not well understood. Here we describe the discovery of two cell density-dependent chemical mediators, nostoclide and nostovalerolactone, in the symbiotic model strain Nostoc punctiforme, and demonstrate their pronounced impact on the regulation of specialized metabolism. Through transcriptional, bioinformatic and labeling studies we assigned two adjacent biosynthetic gene clusters to the biosynthesis of the two polyketide mediators. Our findings provide insight into the orchestration of specialized metabolite production and give lessons for the genomic mining and high-titer production of cyanobacterial bioactive compounds.}, language = {en} } @article{ZeitzReeseBeckmannetal.2021, author = {Zeitz, Maria and Reese, Ronja and Beckmann, Johanna and Krebs-Kanzow, Uta and Winkelmann, Ricarda}, title = {Impact of the melt-albedo feedback on the future evolution of the Greenland Ice Sheet with PISM-dEBM-simple}, series = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union}, volume = {15}, journal = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union}, number = {12}, publisher = {Copernicus}, address = {Katlenburg-Lindau}, issn = {1994-0416}, doi = {10.5194/tc-15-5739-2021}, pages = {5739 -- 5764}, year = {2021}, abstract = {Surface melting of the Greenland Ice Sheet contributes a large amount to current and future sea level rise. Increased surface melt may lower the reflectivity of the ice sheet surface and thereby increase melt rates: the so-called melt-albedo feedback describes this self-sustaining increase in surface melting. In order to test the effect of the melt-albedo feedback in a prognostic ice sheet model, we implement dEBM-simple, a simplified version of the diurnal Energy Balance Model dEBM, in the Parallel Ice Sheet Model (PISM). The implementation includes a simple representation of the melt-albedo feedback and can thereby replace the positive-degree-day melt scheme. Using PISM-dEBM-simple, we find that this feedback increases ice loss through surface warming by 60 \% until 2300 for the high-emission scenario RCP8.5 when compared to a scenario in which the albedo remains constant at its present-day values. With an increase of 90 \% compared to a fixed-albedo scenario, the effect is more pronounced for lower surface warming under RCP2.6. Furthermore, assuming an immediate darkening of the ice surface over all summer months, we estimate an upper bound for this effect to be 70 \% in the RCP8.5 scenario and a more than 4-fold increase under RCP2.6. With dEBM-simple implemented in PISM, we find that the melt-albedo feedback is an essential contributor to mass loss in dynamic simulations of the Greenland Ice Sheet under future warming.}, language = {en} } @article{GoetzKohrsParraHormazabaletal.2021, author = {Goetz, Jason and Kohrs, Robin and Parra Hormaz{\´a}bal, Eric and Bustos Morales, Manuel and Araneda Riquelme, Mar{\´i}a Bel{\´e}n and Henr{\´i}quez Ruiz, Cristian and Brenning, Alexander}, title = {Optimizing and validating the Gravitational Process Path model for regional debris-flow runout modelling}, series = {Natural hazards and earth system sciences : NHESS / European Geophysical Society}, volume = {21}, journal = {Natural hazards and earth system sciences : NHESS / European Geophysical Society}, number = {8}, publisher = {European Geophysical Society}, address = {Katlenburg-Lindau}, issn = {1561-8633}, doi = {10.5194/nhess-21-2543-2021}, pages = {2543 -- 2562}, year = {2021}, abstract = {Knowing the source and runout of debris flows can help in planning strategies aimed at mitigating these hazards. Our research in this paper focuses on developing a novel approach for optimizing runout models for regional susceptibility modelling, with a case study in the upper Maipo River basin in the Andes of Santiago, Chile. We propose a two-stage optimization approach for automatically selecting parameters for estimating runout path and distance. This approach optimizes the random-walk and Perla et al.'s (PCM) two-parameter friction model components of the open-source Gravitational Process Path (GPP) modelling framework. To validate model performance, we assess the spatial transferability of the optimized runout model using spatial crossvalidation, including exploring the model's sensitivity to sample size. We also present diagnostic tools for visualizing uncertainties in parameter selection and model performance. Although there was considerable variation in optimal parameters for individual events, we found our runout modelling approach performed well at regional prediction of potential runout areas. We also found that although a relatively small sample size was sufficient to achieve generally good runout modelling performance, larger samples sizes (i.e. >= 80) had higher model performance and lower uncertainties for estimating runout distances at unknown locations. We anticipate that this automated approach using the open-source R software and the System for Automated Geoscientific Analyses geographic information system (SAGA-GIS) will make process-based debris-flow models more readily accessible and thus enable researchers and spatial planners to improve regional-scale hazard assessments.}, language = {en} } @article{HoehleFritzscheMessetal.2020, author = {H{\"o}hle, Barbara and Fritzsche, Tom and Meß, Katharina and Philipp, Mareike and Gafos, Adamantios I.}, title = {Only the right noise?}, series = {Developmental Science}, volume = {23}, journal = {Developmental Science}, number = {5}, publisher = {Wiley-Blackwell}, address = {Oxford}, issn = {1363-755X}, doi = {10.1111/desc.12950}, pages = {1 -- 16}, year = {2020}, abstract = {Seminal work by Werker and colleagues (Stager \& Werker [1997]Nature, 388, 381-382) has found that 14-month-old infants do not show evidence for learning minimal pairs in the habituation-switch paradigm. However, when multiple speakers produce the minimal pair in acoustically variable ways, infants' performance improves in comparison to a single speaker condition (Rost \& McMurray [2009]Developmental Science, 12, 339-349). The current study further extends these results and assesses how different kinds of input variability affect 14-month-olds' minimal pair learning in the habituation-switch paradigm testing German learning infants. The first two experiments investigated word learning when the labels were spoken by a single speaker versus when the labels were spoken by multiple speakers. In the third experiment we studied whether non-acoustic variability, implemented by visual variability of the objects presented together with the labels, would also affect minimal pair learning. We found enhanced learning in the multiple speakers compared to the single speaker condition, confirming previous findings with English-learning infants. In contrast, visual variability of the presented objects did not support learning. These findings both confirm and better delimit the beneficial role of speech-specific variability in minimal pair learning. Finally, we review different proposals on the mechanisms via which variability confers benefits to learning and outline what may be likely principles that underlie this benefit. We highlight among these the multiplicity of acoustic cues signalling phonemic contrasts and the presence of relations among these cues. It is in these relations where we trace part of the source for the apparent paradoxical benefit of variability in learning.}, language = {en} } @article{Kosta2020, author = {Kosta, Peter}, title = {On extraction and clitic climbing out of subject-/object-control clauses and causative clauses in romance and czech}, series = {Current developments in Slavic linguistics - twenty years after}, journal = {Current developments in Slavic linguistics - twenty years after}, publisher = {Peter Lang}, address = {Berlin}, isbn = {978-3-631-67673-8}, pages = {185 -- 202}, year = {2020}, language = {en} } @article{Botsch2021, author = {Botsch, Gideon}, title = {Ein nach rechts verzerrtes Bild?}, series = {Neue Kriminalpolitik}, volume = {33}, journal = {Neue Kriminalpolitik}, number = {4}, publisher = {Nomos}, address = {Baden-Baden}, issn = {0934-9200}, doi = {10.5771/0934-9200-2021-4-456}, pages = {456 -- 473}, year = {2021}, language = {de} } @article{Botsch2021, author = {Botsch, Gideon}, title = {Taking nativism to the streets}, series = {Moving the social}, volume = {66}, journal = {Moving the social}, publisher = {Institute for Social Movements}, address = {Bochum}, isbn = {978-3-8375-2491-8}, issn = {2197-0386}, doi = {10.46586/mts.66.2021.43-62}, pages = {43 -- 62}, year = {2021}, abstract = {In this article, I give an overview on nativist street protests in Germany from the early nineteenth century to the present from an historical perspective. In a preliminary re-mark, I will reflect on some recent developments in Germany, where nativist protest campaigns against immigration took place in the streets when voters were turning towards the populist radical right party Alternative f{\"u}r Deutschland (AfD). In the first section, I will outline an older tradition of anti-immigration protest in nineteenth and early twentieth century Germany, which is closely connected to modern antisemitism. In sections two and three, I will retrace how, from the late 1960s onward, the far right in the Federal Republic of Germany (FRG) discovered concerns about immigra-tion in the German population, addressed them in protest campaigns and developed narratives to integrate such sentiments into a broader right-wing extremist ideology, itself deeply rooted in antisemitism. Studying nativism and the radical right from an actor-oriented perspective, I will focus on traditionalist movements, including the Nationaldemokratische Partei Deutschlands (NPD) and neo-Nazi groups.}, language = {en} } @article{RubergRothweilerVerissimoetal.2019, author = {Ruberg, Tobias and Rothweiler, Monika and Ver{\´i}ssimo, Jo{\~a}o Marques and Clahsen, Harald}, title = {Childhood bilingualism and Specific Language Impairment}, series = {Bilingualism: Language and Cognition}, volume = {23}, journal = {Bilingualism: Language and Cognition}, number = {3}, publisher = {Cambridge Univ. Press}, address = {Cambridge}, issn = {1366-7289}, doi = {10.1017/S1366728919000580}, pages = {668 -- 680}, year = {2019}, abstract = {This study addresses the question of whether and how growing up with more than one language shapes a child's language impairment. Our focus is on Specific Language Impairment (SLI) in bilingual (Turkish-German) children. We specifically investigated a range of phenomena related to the so-called CP (Complementizer Phrase) in German, the hierarchically highest layer of syntactic clause structure, which has been argued to be particularly affected in children with SLI. Spontaneous speech data were examined from bilingual children with SLI in comparison to two comparison groups: (i) typically-developing bilingual children, (ii) monolingual children with SLI. We found that despite persistent difficulty with subject-verb agreement, the two groups of children with SLI did not show any impairment of the CP-domain. We conclude that while subject-verb agreement is a suitable linguistic marker of SLI in German-speaking children, for both monolingual and bilingual ones, 'vulnerability of the CP-domain' is not.}, language = {en} } @article{Knigge2020, author = {Knigge, Michel}, title = {Use of evidence to promote inclusive education development commentary on Mel Ainscow. Promoting inclusion and equity in education}, series = {Nordic Journal of Studies in Educational Policy}, volume = {6}, journal = {Nordic Journal of Studies in Educational Policy}, number = {1}, publisher = {Taylor \& Francis Group}, address = {London}, issn = {2002-0317}, doi = {10.1080/20020317.2020.1730093}, pages = {21 -- 24}, year = {2020}, abstract = {In his essay, Mel Ainscow looks at inclusion and equity from an international perspective and makes suggestions on how to develop inclusive education in a 'whole-system approach'. After discussing different conceptions of inclusion and equity, he describes international policies which address them. From this international macro-level, Ainscow zooms in to the meso-level of the school and its immediate environment, defining dimensions to be considered for an inclusive school development. One of these dimensions is the 'use of evidence'. In my comment, I want to focus on this dimension and discuss its scope and the potential to apply it in inclusive education development. As a first and important precondition, Ainscow explains that different circumstances lead to different linguistic uses of the term 'inclusive education'. Thus, the term 'inclusive education' does not refer to an identical set of objectives across countries, and neither does the term 'equity'.}, language = {en} } @article{RaafatMrochenAl’Sholuietal.2020, author = {Raafat, Dina and Mrochen, Daniel M. and Al'Sholui, Fawaz and Heuser, Elisa and Ryll, Ren{\´e} and Pritchett-Corning, Kathleen R. and Jacob, Jens and Walther, Bernd and Matuschka, Franz-Rainer and Richter, Dania}, title = {Molecular epidemiology of methicillin-susceptible and methicillin-resistant Staphylococcus aureus in wild, captive and laboratory rats}, series = {Toxins}, volume = {12}, journal = {Toxins}, number = {2}, publisher = {MDPI}, address = {Basel}, issn = {2072-6651}, doi = {10.3390/toxins12020080}, pages = {1 -- 22}, year = {2020}, abstract = {Rats are a reservoir of human- and livestock-associated methicillin-resistant Staphylococcus aureus (MRSA). However, the composition of the natural S. aureus population in wild and laboratory rats is largely unknown. Here, 144 nasal S. aureus isolates from free-living wild rats, captive wild rats and laboratory rats were genotyped and profiled for antibiotic resistances and human-specific virulence genes. The nasal S. aureus carriage rate was higher among wild rats (23.4\%) than laboratory rats (12.3\%). Free-living wild rats were primarily colonized with isolates of clonal complex (CC) 49 and CC130 and maintained these strains even in husbandry. Moreover, upon livestock contact, CC398 isolates were acquired. In contrast, laboratory rats were colonized with many different S. aureus lineages—many of which are commonly found in humans. Five captive wild rats were colonized with CC398-MRSA. Moreover, a single CC30-MRSA and two CC130-MRSA were detected in free-living or captive wild rats. Rat-derived S. aureus isolates rarely harbored the phage-carried immune evasion gene cluster or superantigen genes, suggesting long-term adaptation to their host. Taken together, our study revealed a natural S. aureus population in wild rats, as well as a colonization pressure on wild and laboratory rats by exposure to livestock- and human-associated S. aureus, respectively.}, language = {en} } @article{KumarHesseRaoetal.2020, author = {Kumar, Rohini and Hesse, Fabienne and Rao, P. Srinivasa and Musolff, Andreas and Jawitz, James and Sarrazin, Francois and Samaniego, Luis and Fleckenstein, Jan H. and Rakovec, Oldrich and Thober, S. and Attinger, Sabine}, title = {Strong hydroclimatic controls on vulnerability to subsurface nitrate contamination across Europe}, series = {Nature Communications}, volume = {11}, journal = {Nature Communications}, number = {1}, publisher = {Nature Publishing Group UK}, address = {London}, issn = {2041-1723}, doi = {10.1038/s41467-020-19955-8}, pages = {1 -- 10}, year = {2020}, abstract = {Subsurface contamination due to excessive nutrient surpluses is a persistent and widespread problem in agricultural areas across Europe. The vulnerability of a particular location to pollution from reactive solutes, such as nitrate, is determined by the interplay between hydrologic transport and biogeochemical transformations. Current studies on the controls of subsurface vulnerability do not consider the transient behaviour of transport dynamics in the root zone. Here, using state-of-the-art hydrologic simulations driven by observed hydroclimatic forcing, we demonstrate the strong spatiotemporal heterogeneity of hydrologic transport dynamics and reveal that these dynamics are primarily controlled by the hydroclimatic gradient of the aridity index across Europe. Contrasting the space-time dynamics of transport times with reactive timescales of denitrification in soil indicate that similar to 75\% of the cultivated areas across Europe are potentially vulnerable to nitrate leaching for at least onethird of the year. We find that neglecting the transient nature of transport and reaction timescale results in a great underestimation of the extent of vulnerable regions by almost 50\%. Therefore, future vulnerability and risk assessment studies must account for the transient behaviour of transport and biogeochemical transformation processes.}, language = {en} } @article{SchefflerBoginHermanussen2021, author = {Scheffler, Christiane and Bogin, Barry and Hermanussen, Michael}, title = {Catch-up growth is a better indicator of undernutrition than thresholds for stunting}, series = {Public health nutrition : PHN / The Nutrition Society}, volume = {24}, journal = {Public health nutrition : PHN / The Nutrition Society}, number = {1}, publisher = {Cambridge University Press}, address = {Cambridge ; New York, NY}, issn = {1475-2727}, doi = {10.1017/S1368980020003067}, pages = {52 -- 61}, year = {2021}, abstract = {Objective: Stunting (height-for-age < -2 SD) is one of the forms of undernutrition and is frequent among children of low- and middle-income countries. But stunting perSe is not a synonym of undernutrition. We investigated association between body height and indicators of energetic undernutrition at three critical thresholds for thinness used in public health: (1) BMI SDS < -2; (2) mid-upper arm circumference divided by height (MUAC (mm) × 10/height (cm) < 1·36) and (3) mean skinfold thickness (SF) < 7 mm and to question the reliability of thresholds as indicators of undernutrition. Design: Cross-sectional study; breakpoint analysis. Setting: Rural and urban regions of Indonesia and Guatemala - different socio-economic status (SES). Participants: 1716 Indonesian children (6·0-13·2 years) and 3838 Guatemalan children (4·0-18·9 years) with up to 50 \% stunted children. Results: When separating the regression of BMI, MUAC or SF, on height into distinguishable segments (breakpoint analysis), we failed to detect relevant associations between height, and BMI, MUAC or SF, even in the thinnest and shortest children. For BMI and SF, the breakpoint analysis either failed to reach statistical significance or distinguished at breakpoints above critical thresholds. For MUAC, the breakpoint analysis yielded negative associations between MUAC/h and height in thin individuals. Only in high SES Guatemalan children, SF and height appeared mildly associated with R2 = 0·017. Conclusions: Currently used lower thresholds of height-for-age (stunting) do not show relevant associations with anthropometric indicators of energetic undernutrition. We recommend using the catch-up growth spurt during early re-feeding instead as immediate and sensitive indicator of past undernourishment. We discuss the primacy of education and social-economic-political-emotional circumstances as responsible factors for stunting.}, language = {en} }