@phdthesis{Bajdzienko2017,
  author    = {Bajdzienko, Krzysztof},
  title     = {Analysis of Target of Rapamycin (Tor) induced changes of the Arabidopsis thaliana proteome using sub-cellular resolution},
  school      = {Universit{\"a}t Potsdam},
  pages     = {167},
  year      = {2017},
  language  = {en}
}
@article{AttermeyerGrossartFluryetal.2017,
  author    = {Attermeyer, Katrin and Grossart, Hans-Peter and Flury, Sabine and Premke, Katrin},
  title     = {Bacterial processes and biogeochemical changes in the water body of kettle holes - mainly driven by autochthonous organic matter?},
  series = {Aquatic sciences : research across boundaries},
  volume    = {79},
  journal   = {Aquatic sciences : research across boundaries},
  publisher = {Springer},
  address   = {Basel},
  issn      = {1015-1621},
  doi       = {10.1007/s00027-017-0528-1},
  pages     = {675 -- 687},
  year      = {2017},
  abstract  = {Kettle holes are small inland waters formed from glacially-created depressions often situated in agricultural landscapes. Due to their high perimeter-to-area ratio facilitating a high aquatic-terrestrial coupling, kettle holes can accumulate high concentrations of organic carbon and nutrients, fueling microbial activities and turnover rates. Thus, they represent hotspots of carbon turnover in the landscape, but their bacterial activities and controlling factors have not been well investigated. Therefore, we aimed to assess the relative importance of various environmental factors on bacterial and biogeochemical processes in the water column of kettle holes and to disentangle their variations. In the water body of ten kettle holes in north-eastern Germany, we measured several physico-chemical and biological parameters such as carbon quantity and quality, as well as bacterial protein production (BP) and community respiration (CR) in spring, early summer and autumn 2014. Particulate organic matter served as an indicator of autochthonous production and represented an important parameter to explain variations in BP and CR. This notion is supported by qualitative absorbance indices of dissolved molecules in water samples and C: N ratios of the sediments, which demonstrate high fractions of autochthonous organic matter (OM) in the studied kettle holes. In contrast, dissolved chemical parameters were less important for bacterial activities although they revealed strong differences throughout the growing season. Pelagic bacterial activities and dynamics might thus be regulated by autochthonous OM in kettle holes implying a control of important biogeochemical processes by internal primary production rather than facilitated exchange with the terrestrial surrounding due to a high perimeter-to-area ratio.},
  language  = {en}
}
@article{ApeltBreuerOlasetal.2017,
  author    = {Apelt, Federico and Breuer, David and Olas, Justyna Jadwiga and Annunziata, Maria Grazia and Flis, Anna and Nikoloski, Zoran and Kragler, Friedrich and Stitt, Mark},
  title     = {Circadian, Carbon, and Light Control of Expansion Growth and Leaf Movement},
  series = {Plant physiology : an international journal devoted to physiology, biochemistry, cellular and molecular biology, biophysics and environmental biology of plants},
  volume    = {174},
  journal   = {Plant physiology : an international journal devoted to physiology, biochemistry, cellular and molecular biology, biophysics and environmental biology of plants},
  publisher = {American Society of Plant Physiologists},
  address   = {Rockville},
  issn      = {0032-0889},
  doi       = {10.1104/pp.17.00503},
  pages     = {1949 -- 1968},
  year      = {2017},
  language  = {en}
}
@article{AmalfitanoCornoEckertetal.2017,
  author    = {Amalfitano, Stefano and Corno, Gianluca and Eckert, Ester and Fazi, Stefano and Ninio, Shira and Callieri, Cristiana and Grossart, Hans-Peter and Eckert, Werner},
  title     = {Tracing particulate matter and associated microorganisms in freshwaters},
  series = {Hydrobiologia : acta hydrobiologica, hydrographica, limnologica et protistologica},
  volume    = {800},
  journal   = {Hydrobiologia : acta hydrobiologica, hydrographica, limnologica et protistologica},
  publisher = {Springer},
  address   = {Dordrecht},
  issn      = {0018-8158},
  doi       = {10.1007/s10750-017-3260-x},
  pages     = {145 -- 154},
  year      = {2017},
  abstract  = {Sediment resuspension represents a key process in all natural aquatic systems, owing to its role in nutrient cycling and transport of potential contaminants. Although suspended solids are generally accepted as an important quality parameter, current monitoring programs cover quantitative aspects only. Established methodologies do not provide information on origin, fate, and risks associated with uncontrolled inputs of solids in waters. Here we discuss the analytical approaches to assess the occurrence and ecological relevance of resuspended particulate matter in freshwaters, with a focus on the dynamics of associated contaminants and microorganisms. Triggered by the identification of specific physical-chemical traits and community structure of particle-associated microorganisms, recent findings suggest that a quantitative determination of microorganisms can be reasonably used to trace the origin of particulate matter by means of nucleic acid-based assays in different aquatic systems.},
  language  = {en}
}
@article{AlluSimancasBalazadehetal.2017,
  author    = {Allu, Annapurna Devi and Simancas, Barbara and Balazadeh, Salma and Munne-Bosch, Sergi},
  title     = {Defense-Related Transcriptional Reprogramming in Vitamin E-Deficient Arabidopsis Mutants Exposed to Contrasting Phosphate Availability},
  series = {Frontiers in plant science},
  volume    = {8},
  journal   = {Frontiers in plant science},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-462X},
  doi       = {10.3389/fpls.2017.01396},
  pages     = {20},
  year      = {2017},
  abstract  = {Vitamin E inhibits the propagation of lipid peroxidation and helps protecting photosystem II from photoinhibition, but little is known about its possible role in plant response to Pi availability. Here, we aimed at examining the effect of vitamin E deficiency in Arabidopsis thaliana vte mutants on phytohormone contents and the expression of transcription factors in plants exposed to contrasting Pi availability. Plants were subjected to two doses of Pi, either unprimed (controls) or previously exposed to low Pi (primed). In the wild type, alpha-tocopherol contents increased significantly in response to repeated periods of low Pi, which was paralleled by increased growth, indicative of a priming effect. This growth-stimulating effect was, however, abolished in vte mutants. Hormonal profiling revealed significant effects of Pi availability, priming and genotype on the contents of jasmonates and salicylates; remarkably, vte mutants showed enhanced accumulation of both hormones under low Pi. Furthermore, expression profiling of 1,880 transcription factors by qRT-PCR revealed a pronounced effect of priming on the transcript levels of 45 transcription factors mainly associated with growth and stress in wild-type plants in response to low Pi availability; while distinct differences in the transcriptional response were detected in vte mutants. We conclude that alpha-tocopherol plays a major role in the response of plants to Pi availability not only by protecting plants from photo-oxidative stress, but also by exerting a control over growth-and defense-related transcriptional reprogramming and hormonal modulation.},
  language  = {en}
}
@misc{AlirezaeizanjaniWaljorHintscheetal.2017,
  author    = {Alirezaeizanjani, Zahra and Waljor, V. and Hintsche, Marius and Beta, Carsten},
  title     = {How growth conditions affect bacterial chemotaxis responses},
  series = {European biophysics journal : with biophysics letters ; an international journal of biophysics},
  volume    = {46},
  journal   = {European biophysics journal : with biophysics letters ; an international journal of biophysics},
  publisher = {Springer},
  address   = {New York},
  issn      = {0175-7571},
  pages     = {S281 -- S281},
  year      = {2017},
  language  = {en}
}
@article{AhmedReynaGonzalezSchmidetal.2017,
  author    = {Ahmed, Muhammad N. and Reyna-Gonzalez, Emmanuel and Schmid, Bianca and Wiebach, Vincent and Suessmuth, Roderich D. and Dittmann, Elke and Fewer, David P.},
  title     = {Phylogenomic Analysis of the Microviridin Biosynthetic Pathway Coupled with Targeted Chemo-Enzymatic Synthesis Yields Potent Protease Inhibitors},
  series = {ACS chemical biology},
  volume    = {12},
  journal   = {ACS chemical biology},
  publisher = {American Chemical Society},
  address   = {Washington},
  issn      = {1554-8929},
  doi       = {10.1021/acschembio.7b00124},
  pages     = {1538 -- 1546},
  year      = {2017},
  abstract  = {Natural products and their semisynthetic derivatives are an important source of drugs for the pharmaceutical industry. Bacteria are prolific producers of natural products and encode a vast diversity of natural product biosynthetic gene clusters. However, much of this diversity is inaccessible to natural product discovery. Here, we use a combination of phylogenomic analysis of the microviridin biosynthetic pathway and chemo-enzymatic synthesis of bioinformatically predicted microviridins to yield new protease inhibitors. Phylogenomic analysis demonstrated that microviridin biosynthetic gene clusters occur across the bacterial domain and encode three distinct subtypes of precursor peptides. Our analysis shed light on the evolution of microviridin biosynthesis and enabled prioritization of their chemo-enzymatic production. Targeted one-pot synthesis of four microviridins encoded by the cyanobacterium Cyanothece sp. PCC 7822 identified a set of novel and potent serine protease inhibitors, the most active of which had an IC50 value of 21.5 nM. This study advances the genome mining techniques available for natural product discovery and obviates the need to culture bacteria.},
  language  = {en}
}
@article{AbrahamczykLozadaGobilardAckermannetal.2017,
  author    = {Abrahamczyk, Stefan and Lozada Gobilard, Sissi Donna and Ackermann, Markus and Fischer, Eberhard and Krieger, Vera and Redling, Almut and Weigend, Maximilian},
  title     = {A question of data quality-Testing pollination syndromes in Balsaminaceae},
  series = {PLoS one},
  volume    = {12},
  journal   = {PLoS one},
  publisher = {PLoS},
  address   = {San Fransisco},
  issn      = {1932-6203},
  doi       = {10.1371/journal.pone.0186125},
  pages     = {14},
  year      = {2017},
  abstract  = {Pollination syndromes and their predictive power regarding actual plant-animal interactions have been controversially discussed in the past. We investigate pollination syndromes in Balsaminaceae, utilizing quantitative respectively categorical data sets of flower morphometry, signal and reward traits for 86 species to test for the effect of different types of data on the test patterns retrieved. Cluster Analyses of the floral traits are used in combination with independent pollinator observations. Based on quantitative data we retrieve seven clusters, six of them corresponding to plausible pollination syndromes and one additional, well-supported cluster comprising highly divergent floral architectures. This latter cluster represents a non-syndrome of flowers not segregated by the specific data set here used. Conversely, using categorical data we obtained only a rudimentary resolution of pollination syndromes, in line with several earlier studies. The results underscore that the use of functional, exactly quanitified trait data has the power to retrieve pollination syndromes circumscribed by the specific data used. Data quality can, however, not be replaced by sheer data volume. With this caveat, it is possible to identify pollination syndromes from large datasets and to reliably extrapolate them for taxa for which direct observations are unavailable.},
  language  = {en}
}
@book{OPUS4-56684,
  title     = {Drug target miRNA},
  series = {Methods in Molecular Biology},
  journal   = {Methods in Molecular Biology},
  editor    = {Schmidt, Marco F.},
  publisher = {Springer},
  address   = {New York},
  isbn      = {978-1-4939-6561-8},
  issn      = {1064-3745},
  doi       = {10.1007/978-1-4939-6563-2},
  pages     = {320},
  year      = {2017},
  abstract  = {This volume provides a concise and technical discussion of recently developed approaches to overcome challenges in miRNA drug discovery. Drug Target miRNA: Methods and Protocols explores strategies to overcome pharmacodynamics and pharmacokinetics challenges. These strategies cover anti-sense agents targeting miRNA that are applied in advanced formulations or are chemically optimized to increase delivery; small molecule miRNA modulators to overcome anti-sense agents' limitations; general enhancers of miRNA maturation; and Argonaute 2 protein and its pharmacokinetic parameters. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, Drug Target miRNA: Methods and Protocols is a valuable resource for anyone interested in the ever-evolving field of miRNA drug discovery.},
  language  = {en}
}
@article{OPUS4-56760,
  title     = {Plant Hormones},
  series = {Methods in Molecular Biology},
  journal   = {Methods in Molecular Biology},
  number    = {1497},
  editor    = {Kleine-Vehn, J{\"u}rgen and Sauer, Michael},
  publisher = {Springer},
  address   = {New York},
  isbn      = {978-1-4939-6467-3},
  issn      = {1064-3745},
  doi       = {10.1007/978-1-4939-6469-7},
  pages     = {XI, 288},
  year      = {2017},
  abstract  = {This volume aims to present a representative cross-section of modern experimental approaches relevant to Plant Hormone Biology, ranging from relatively simple physiological to highly sophisticated methods. Chapters describe physiological, developmental, microscopy-based techniques, measure hormone contents, and heterologous systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.},
  language  = {en}
}