@article{SeckerBrosnanLuxenhoferetal.2015, author = {Secker, Christian and Brosnan, Sarah M. and Luxenhofer, Robert and Schlaad, Helmut}, title = {Poly(alpha-Peptoid)s Revisited: Synthesis, Properties, and Use as Biomaterial}, series = {Macromolecular bioscience}, volume = {15}, journal = {Macromolecular bioscience}, number = {7}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1616-5187}, doi = {10.1002/mabi.201500023}, pages = {881 -- 891}, year = {2015}, abstract = {Polypeptoids have been of great interest in the polymer science community since the early half of the last century; however, they had been basically forgotten materials until the last decades in which they have enjoyed an exciting revival. In this mini-review, we focus on the recent developments in polypeptoid chemistry, with particular focus on polymers synthesized by the ring-opening polymerization (ROP) of amino acid N-carboxyanhydrides (NCAs). Specifically, we will review traditional monomer synthesis (such as Leuchs, Katchalski, and Kricheldorf) and recent advances in polymerization methods to yield both linear, cyclic, and functional polymers, solution and bulk thermal properties, and preliminary results on the use of polypeptoids as biomaterials (i.e immunogenicity, biodistribution, degradability, and drug delivery).}, language = {en} } @misc{DoritiBrosnanWeidneretal.2016, author = {Doriti, Afroditi and Brosnan, Sarah M. and Weidner, Steffen M. and Schlaad, Helmut}, title = {Synthesis of polysarcosine from air and moisture stable N-phenoxycarbonyl-N-methylglycine assisted by tertiary amine base}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-95852}, pages = {3067 -- 3070}, year = {2016}, abstract = {Polysarcosine (Mn = 3650-20 000 g mol-1, Đ ∼ 1.1) was synthesized from the air and moisture stable N-phenoxycarbonyl-N-methylglycine. Polymerization was achieved by in situ transformation of the urethane precursor into the corresponding N-methylglycine-N-carboxyanhydride, when in the presence of a non-nucleophilic tertiary amine base and a primary amine initiator.}, language = {en} } @article{DoritiBrosnanWeidneretal.2016, author = {Doriti, Afroditi and Brosnan, Sarah M. and Weidner, Steffen M. and Schlaad, Helmut}, title = {Synthesis of polysarcosine from air and moisture stable N-phenoxycarbonyl-N-methylglycine assisted by tertiary amine base}, series = {Polymer Chemistry}, volume = {7}, journal = {Polymer Chemistry}, publisher = {RSC Publ.}, address = {Cambridge}, issn = {1759-9954}, doi = {10.1039/C6PY00221H}, pages = {3067 -- 3070}, year = {2016}, abstract = {Polysarcosine (Mn = 3650-20 000 g mol-1, Đ ∼ 1.1) was synthesized from the air and moisture stable N-phenoxycarbonyl-N-methylglycine. Polymerization was achieved by in situ transformation of the urethane precursor into the corresponding N-methylglycine-N-carboxyanhydride, when in the presence of a non-nucleophilic tertiary amine base and a primary amine initiator.}, language = {en} }