@article{CzarneckiWessig2018, author = {Czarnecki, Maciej and Wessig, Pablo}, title = {Scaling Up UV-Mediated Intramolecular Photodehydro-Diels-Alder Reactions Using a Homemade High-Performance Annular Continuous-Flow Reactor}, series = {Organic Process Research \& Development}, volume = {22}, journal = {Organic Process Research \& Development}, number = {12}, publisher = {American Chemical Society}, address = {Washington}, issn = {1083-6160}, doi = {10.1021/acs.oprd.8b00353}, pages = {1823 -- 1827}, year = {2018}, abstract = {Here we present a self-made annular continuous-flow reactor that can be used in the UV/vis range in an internal numbering-up manner. As a model reaction, we chose a powerful batch-scale-limited benzoannelation method, namely, an intramolecular photodehydro-Diels-Alder (IMPDDA) reaction. The scale-up potential of this particular photochemical benchmark reaction toward the preparation of macrocylic (1,7)naphthalenophanes by variation of selected flow parameters is presented.}, language = {en} }