@article{RohnerFreyMothesetal.2011, author = {Rohner, Fabian and Frey, Simone K. and Mothes, Ralf and Hurtienne, Andrea and Hartong, Simone and Bosso, Patrice Emery and Bui, Mai and Schweigert, Florian J. and Northrop-Clewes, Christine}, title = {Quantification of vitamin A in palm oil using a fast and simple portable device method validation and comparison to high-performance liquid chromatography}, series = {International journal for vitamin and nutrition research}, volume = {81}, journal = {International journal for vitamin and nutrition research}, number = {5}, publisher = {Hogrefe}, address = {Bern}, issn = {0300-9831}, doi = {10.1024/0300-9831/a000081}, pages = {335 -- 342}, year = {2011}, abstract = {Vitamin A deficiency continues to be a global public health problem. Fortification of oil with vitamin A is considered a cost-effective, feasible strategy to prevent this problem but quality control poses a challenge to program implementation. To overcome this, we have validated a newly developed device that quantitatively measures the content of retinyl palmitate in refined palm oil, is simple to use, and yields immediate results. Linearity of analysis rand from 2.5-30 mg retinol equivalents (RE)/kg of palm oil, with 2.5 mg RE/kg being the determination limit; inter- and intra-assay precision ranged from 1.4-7.1 To. Comparison with a high-performance Liquid chromatography method showed high agreement between the methods (R-2 = 0.92; Limits of Agreement: -1.24 mg to 2.53 mg RE/kg), and further comparisons illustrate that the new device is useful in low resource settings. This device offers a field- and user-friendly solution to quantifying the vitamin A content in refined palm oil.}, language = {en} } @article{RohnerGarrettLaillouetal.2012, author = {Rohner, Fabian and Garrett, Greg S. and Laillou, Arnaud and Frey, Simone K. and Mothes, Ralf and Schweigert, Florian J. and Locatelli-Rossi, Lorenzo}, title = {Validation of a user-friendly and rapid method for quantifying iodine content of salt}, series = {Food and nutrition bulletin}, volume = {33}, journal = {Food and nutrition bulletin}, number = {4}, publisher = {International Nutrition Foundation}, address = {Boston}, issn = {0379-5721}, pages = {S330 -- S335}, year = {2012}, abstract = {Background. Despite considerable progress made in the past decade through salt iodization programs, over 2 billion people worldwide still have inadequate iodine intake, with devastating consequences for brain development and intellectual capacity. To optimize these programs with regard to salt iodine content, careful monitoring of salt iodine content is essential, but few methods are available to quantitatively measure iodine concentration in a simple, fast, and safe way. Objective. We have validated a newly developed device that quantitatively measures the content of potassium iodate in salt in a simple, safe, and rapid way. Methods. The linearity, determination and detection limit, and inter- and intra-assay variability of this colorimetric method were assessed and the method was compared with iodometric titration, using salt samples from several countries. Results. Linearity of analysis ranged from 5 to 75 mg/kg iodine, with I mg/kg being the determination limit; the intra- and interassay imprecision was 0.9\%, 0.5\%, and 0.7\% and 1.5\%, 1.7\%, and 2.5\% for salt samples with iodine contents of 17, 30, and 55 mg/kg, respectively; the interoperator imprecision for the same samples was 1.2\%, 4.9\%, and 4.7\%, respectively. Comparison with the iodometric method showed high agreement between the methods (R-2 = 0.978; limits of agreement, -10.5 to 10.0 mg/kg). Conclusions. The device offers a field- and user-friendly solution to quantifying potassium iodate salt content reliably. For countries that use potassium iodide in salt iodization programs, further validation is required.}, language = {en} }