@article{SendBardtkeGillesetal.2019, author = {Send, Tabea and Bardtke, S. and Gilles, M. and Wolf, I. A. C. and S{\"u}tterlin, Marc Wolf and Wudy, S. A. and Wang, R. and Laucht, Manfred and Witt, Stephanie H. and Rietschel, Marcella and Streit, Fabian and Deuschle, Michael}, title = {Prenatal maternal stress is associated with lower cortisol and cortisone levels in the first morning urine of 45-month-old children}, series = {Psychoneuroendocrinology}, volume = {103}, journal = {Psychoneuroendocrinology}, publisher = {Elsevier}, address = {Oxford}, issn = {0306-4530}, doi = {10.1016/j.psyneuen.2019.01.017}, pages = {219 -- 224}, year = {2019}, abstract = {Prenatal stress (PS) has been related to altered hypothalamic-pituitary-adrenal (HPA) axis activity later in life. So far, studies in children assessing HPA axis functioning have focused on salivary cortisol, reflecting daytime activity. The present work is part of a prospective study and aims to extend knowledge about the association between PS and HPA axis regulation in children. To do so, we investigated cortisol, cortisone, and the ratio cortisone/(cortisone + cortisol) in the first morning urine of 45-month-old children in relation to several measures of maternal stress during pregnancy. Urinary cortisol and cortisone were measured by online turbulent flow chromatography coupled with high performance liquid chromatography-tandem mass spectrometry. PS was defined as: perceived stress for aim 1 (Perceived Stress Scale; n = 280); presence of self-reported (n = 371) and expert-rated psychopathology for aim 2 (Mini International Neuropsychiatric Interview; n = 281); continuous measures of anxiety and depression for exploratory aim 3 (State-Trait Anxiety Inventory and Edinburgh Postnatal Depression Scale; n = 280). The ratio cortisone/(cortisone + cortisol) as a global marker for the balance between the enzymes metabolizing cortisol to cortisone and vice versa (11 beta-hydroxysteroid dehydrogenases type 1 and 2; 11 beta-HSD1 and 2) was not associated with any measure of maternal PS (aims 1-3). The present study provides insight into possible programming effects of PS on nocturnal HPA axis activity and a proxy of 11 beta-HSD in a large sample. The results suggest that the nocturnal rate of cortisol production is lower in children exposed to PS, but do not support the hypothesis of divergent 11 beta-HSD activity.}, language = {en} } @article{HerppichMartinToetzkeetal.2019, author = {Herppich, Werner B. and Martin, Craig E. and T{\"o}tzke, Christian and Manke, Ingo and Kardjilov, Nikolay}, title = {External water transport is more important than vascular transport in the extreme atmospheric epiphyte Tillandsia usneoides (Spanish moss)}, series = {Plant, cell \& environment : cell physiology, whole-plant physiology, community physiology}, volume = {42}, journal = {Plant, cell \& environment : cell physiology, whole-plant physiology, community physiology}, number = {5}, publisher = {Wiley}, address = {Hoboken}, issn = {0140-7791}, doi = {10.1111/pce.13496}, pages = {1645 -- 1656}, year = {2019}, abstract = {Most epiphytic bromeliads, especially those in the genus Tillandsia, lack functional roots and rely on the absorption of water and nutrients by large, multicellular trichomes on the epidermal surfaces of leaves and stems. Another important function of these structures is the spread of water over the epidermal surface by capillary action between trichome "wings" and epidermal surface. Although critical for the ultimate absorption by these plants, understanding of this function of trichomes is primarily based on light microscope observations. To better understand this phenomenon, the distribution of water was followed by its attenuation of cold neutrons following application of H2O to the cut end of Tillandsia usneoides shoots. Experiments confirmed the spread of added water on the external surfaces of this "atmospheric" epiphyte. In a morphologically and physiologically similar plant lacking epidermal trichomes, water added to the cut end of a shoot clearly moved via its internal xylem and not on its epidermis. Thus, in T. usneoides, water moves primarily by capillarity among the overlapping trichomes forming a dense indumentum on shoot surfaces, while internal vascular water movement is less likely. T. usneoides, occupying xeric microhabitats, benefits from reduction of water losses by low-shoot xylem hydraulic conductivities.}, language = {en} } @article{SchmidtLischeidNendel2019, author = {Schmidt, Martin and Lischeid, Gunnar and Nendel, Claas}, title = {Microclimate and matter dynamics in transition zones of forest to arable land}, series = {Agricultural and forest meteorology}, volume = {268}, journal = {Agricultural and forest meteorology}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0168-1923}, doi = {10.1016/j.agrformet.2019.01.001}, pages = {1 -- 10}, year = {2019}, abstract = {Human-driven fragmentation of landscapes leads to the formation of transition zones between ecosystems that are characterised by fluxes of matter, energy and information. These transition zones may offer rather inhospitable habitats that could jeopardise biodiversity. On the other hand, transition zones are also reported to be hotspots for biodiversity and even evolutionary processes. The general mechanisms and influence of processes in transition zones are poorly understood. Although heterogeneity and diversity of land use of fragments and the transition zones between them play an important role, most studies only refer to forested transition zones. Often, only an extrapolation of measurements in the different fragments themselves is reported to determine gradients in transition zones. This paper contributes to a quantitative understanding of agricultural landscapes beyond individual ecotopes, and towards connected ecosystem mosaics that may be beneficial for the provision of ecosystem services.}, language = {en} } @article{YanChenSchumacheretal.2019, author = {Yan, Wenhao and Chen, Dijun and Schumacher, Julia and Durantini, Diego and Engelhorn, Julia and Chen, Ming and Carles, Cristel C. and Kaufmann, Kerstin}, title = {Dynamic control of enhancer activity drives stage-specific gene expression during flower morphogenesis}, series = {Nature Communications}, volume = {10}, journal = {Nature Communications}, publisher = {Nature Publ. Group}, address = {London}, issn = {2041-1723}, doi = {10.1038/s41467-019-09513-2}, pages = {16}, year = {2019}, abstract = {Enhancers are critical for developmental stage-specific gene expression, but their dynamic regulation in plants remains poorly understood. Here we compare genome-wide localization of H3K27ac, chromatin accessibility and transcriptomic changes during flower development in Arabidopsis. H3K27ac prevalently marks promoter-proximal regions, suggesting that H3K27ac is not a hallmark for enhancers in Arabidopsis. We provide computational and experimental evidence to confirm that distal DNase. hypersensitive sites are predictive of enhancers. The predicted enhancers are highly stage-specific across flower development, significantly associated with SNPs for flowering-related phenotypes, and conserved across crucifer species. Through the integration of genome-wide transcription factor (TF) binding datasets, we find that floral master regulators and stage-specific TFs are largely enriched at developmentally dynamic enhancers. Finally, we show that enhancer clusters and intronic enhancers significantly associate with stage-specific gene regulation by floral master TFs. Our study provides insights into the functional flexibility of enhancers during plant development, as well as hints to annotate plant enhancers.}, language = {en} } @misc{Hickmann2019, author = {Hickmann, Thomas}, title = {Rezension zu: Andonova, Liliana B: Governance Entrepreneurs: International Organizations and the Rise of Global Public-Private Partnerships. - Cambridge: Cambridge University Press, 2017. - XI,275 S. - ISBN 978-1-107-16566-3}, series = {Global environmental politics}, volume = {19}, journal = {Global environmental politics}, number = {2}, publisher = {MIT Press}, address = {Cambridge}, issn = {1526-3800}, doi = {10.1162/glep_r_00510}, pages = {175 -- 177}, year = {2019}, language = {en} } @article{GuislainBeisnerKoehler2019, author = {Guislain, Alexis and Beisner, Beatrix E. and K{\"o}hler, Jan}, title = {Variation in species light acquisition traits under fluctuating light regimes}, series = {Oikos}, volume = {128}, journal = {Oikos}, number = {5}, publisher = {Wiley}, address = {Hoboken}, issn = {0030-1299}, doi = {10.1111/oik.05297}, pages = {716 -- 728}, year = {2019}, abstract = {Resource distribution heterogeneity offers niche opportunities for species with different functional traits to develop and potentially coexist. Available light (photosynthetically active radiation or PAR) for suspended algae (phytoplankton) may fluctuate greatly over time and space. Species-specific light acquisition traits capture important aspects of the ecophysiology of phytoplankton and characterize species growth at either limiting or saturating daily PAR supply. Efforts have been made to explain phytoplankton coexistence using species-specific light acquisition traits under constant light conditions, but not under fluctuating light regimes that should facilitate non-equilibrium coexistence. In the well-mixed, hypertrophic Lake TaiHu (China), we incubated the phytoplankton community in bottles placed either at fixed depths or moved vertically through the water column to mimic vertical mixing. Incubations at constant depths received only the diurnal changes in light, while the moving bottles received rapidly fluctuating light. Species-specific light acquisition traits of dominant cyanobacteria (Anabaena flos-aquae, Microcystis spp.) and diatom (Aulacoseira granulata, Cyclotella pseudostelligera) species were characterized from their growth-light relationships that could explain relative biomasses along the daily PAR gradient under both constant and fluctuating light. Our study demonstrates the importance of interspecific differences in affinities to limiting and saturating light for the coexistence of phytoplankton species in spatially heterogeneous light conditions. Furthermore, we observed strong intraspecific differences in light acquisition traits between incubation under constant and fluctuating light - leading to the reversal of light utilization strategies of species. This increased the niche space for acclimated species, precluding competitive exclusion. These observations could enhance our understanding of the mechanisms behind the Paradox of the Plankton.}, language = {en} } @article{delaCruzMachensMesserschmidtetal.2019, author = {de la Cruz, Jorge Gonzalez and Machens, Fabian and Messerschmidt, Katrin and Bar-Even, Arren}, title = {Core Catalysis of the Reductive Glycine Pathway Demonstrated in Yeast}, series = {ACS synthetic biology}, volume = {8}, journal = {ACS synthetic biology}, number = {5}, publisher = {American Chemical Society}, address = {Washington}, issn = {2161-5063}, doi = {10.1021/acssynbio.8b00464}, pages = {911 -- 917}, year = {2019}, abstract = {One-carbon (C1) compounds are attractive microbial feedstocks as they can be efficiently produced from widely available resources. Formate, in particular, represents a promising growth substrate, as it can be generated from electrochemical reduction of CO2 and fed to microorganisms in a soluble form. We previously identified the synthetic reductive glycine pathway as the most efficient route for aerobic growth on formate. We further demonstrated pathway activity in Escherichia coli after expression of both native and foreign genes. Here, we explore whether the reductive glycine pathway could be established in a model microorganism using only native enzymes. We used the yeast Saccharomyces cerevisiae as host and show that overexpression of only endogenous enzymes enables glycine biosynthesis from formate and CO2 in a strain that is otherwise auxotrophic for glycine. We find the pathway to be highly active in this host, where 0.125 mM formate is sufficient to support growth. Notably, the formate-dependent growth rate of the engineered S. cerevisiae strain remained roughly constant over a very wide range of formate concentrations, 1-500 mM, indicating both high affinity for formate use and high tolerance toward elevated concentration of this C1 feedstock. Our results, as well the availability of endogenous NAD-dependent formate dehydrogenase, indicate that yeast might be an especially suitable host for engineering growth on formate.}, language = {en} } @article{AshtonEugsterDietzetal.2019, author = {Ashton, Michelle P. and Eugster, Anne and Dietz, Sevina and Loebel, Doreen and Lindner, Annett and Kuehn, Denise and Taranko, Anna E. and Heschel, Babett and Gavrisan, Anita and Ziegler, Anette-Gabriele and Aringer, Martin and Bonifacio, Ezio}, title = {Association of Dendritic Cell Signatures With Autoimmune Inflammation Revealed by Single-Cell Profiling}, series = {Arthrittis \& Rheumatology}, volume = {71}, journal = {Arthrittis \& Rheumatology}, number = {5}, publisher = {Wiley}, address = {Hoboken}, issn = {2326-5191}, doi = {10.1002/art.40793}, pages = {817 -- 828}, year = {2019}, language = {en} } @article{MeyerKalkus2019, author = {Meyer-Kalkus, Reinhart}, title = {Dramenvorlesen als Kunst - das Beispiel Ludwig Tiecks}, series = {Belebungsk{\"u}nste : Praktiken lebendiger Darstellung in Literatur, Kunst und Wissenschaft um 1800}, journal = {Belebungsk{\"u}nste : Praktiken lebendiger Darstellung in Literatur, Kunst und Wissenschaft um 1800}, publisher = {Fink}, address = {Paderborn}, isbn = {978-3-7705-6292-3}, doi = {10.30965/9783846762929_005}, pages = {61 -- 82}, year = {2019}, language = {de} } @article{AltintasTakidenUteschetal.2019, author = {Altintas, Zeynep and Takiden, Aref and Utesch, Tillmann and Mroginski, Maria A. and Schmid, Bianca and Scheller, Frieder W. and S{\"u}ssmuth, Roderich D.}, title = {Integrated approaches toward high-affinity artificial protein binders obtained via computationally simulated epitopes for protein recognition}, series = {Advanced functional materials}, volume = {29}, journal = {Advanced functional materials}, number = {15}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1616-301X}, doi = {10.1002/adfm.201807332}, pages = {11}, year = {2019}, abstract = {Widely used diagnostic tools make use of antibodies recognizing targeted molecules, but additional techniques are required in order to alleviate the disadvantages of antibodies. Herein, molecular dynamic calculations are performed for the design of high affinity artificial protein binding surfaces for the recognition of neuron specific enolase (NSE), a known cancer biomarker. Computational simulations are employed to identify particularly stabile secondary structure elements. These epitopes are used for the subsequent molecular imprinting, where surface imprinting approach is applied. The molecular imprints generated with the calculated epitopes of greater stability (Cys-Ep1) show better binding properties than those of lower stability (Cys-Ep5). The average binding strength of imprints created with stabile epitopes is found to be around twofold and fourfold higher for the NSE derived peptide and NSE protein, respectively. The recognition of NSE is investigated in a wide concentration range, where high sensitivity (limit of detection (LOD) = 0.5 ng mL(-1)) and affinity (dissociation constant (K-d) = 5.3 x 10(-11)m) are achieved using Cys-Ep1 imprints reflecting the stable structure of the template molecules. This integrated approach employing stability calculations for the identification of stabile epitopes is expected to have a major impact on the future development of high affinity protein capturing binders.}, language = {en} } @misc{NeumannQuintingRosenkranzetal.2019, author = {Neumann, Sandra and Quinting, Jana and Rosenkranz, Anna and De Beer, Carola and Jonas, Kristina and Stenneken, Prisca}, title = {Quality of life in adults with neurogenic speech-language-communication difficulties}, series = {Journal of communication disorders}, volume = {79}, journal = {Journal of communication disorders}, publisher = {Elsevier}, address = {New York}, issn = {0021-9924}, doi = {10.1016/j.jcomdis.2019.01.003}, pages = {24 -- 45}, year = {2019}, language = {en} } @misc{EkkekakisBrand2019, author = {Ekkekakis, Panteleimon and Brand, Ralf}, title = {Affective responses to and automatic affective valuations of physical activity}, series = {Psychology of sport and exercise}, volume = {42}, journal = {Psychology of sport and exercise}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1469-0292}, doi = {10.1016/j.psychsport.2018.12.018}, pages = {130 -- 137}, year = {2019}, abstract = {Objective: To critically review developments over the first fifty years of research (1967-2017) on (a) how people feel when they participate in exercise and physical activity, and (b) the implications of these responses for their willingness to become and remain active. Design: Non-systematic narrative review. Method: Representative sources were selected through a combination of computer searches and cross-referencing. Results: For over three decades, exercise psychology exhibited a fixation on the idea that exercise and physical activity make people feel better. This notion, however, seemed to contrast with evidence that most adults in industrialized countries exhibit low levels of activity. In the last two decades, a critical examination and overhaul of the methodological platform resulted in the delineation of a dose-response pattern that encompasses positive as well as negative affective responses, and revealed marked interindividual differences. An emerging literature is aimed at refining and testing integrative dual-process models that can offer specific predictions about the behaviors that may result from the interaction of automatic processes (theorized to be heavily influenced by past affective experiences) and deliberative processes (such as cognitive appraisals). Conclusions: Affective responses to exercise and physical activity are more complex than the long-popularized "feel-better" effect, encompassing both pleasant and unpleasant experiences and exhibiting marked inter individual variation. The potential of affective experiences to influence subsequent behavior offers an opportunity for an expanded theoretical perspective in exercise psychology.}, language = {en} } @article{KaufmannHoffmannBachmannetal.2019, author = {Kaufmann, Felix E. D. and Hoffmann, Marie C. and Bachmann, Kai and Veksler, Ilya V. and Trumbull, Robert B. and Hecht, Lutz}, title = {Variations in Composition, Texture, and Platinum Group Element Mineralization in the Lower Group and Middle Group Chromitites of the Northwestern Bushveld Complex, South Africa}, series = {Economic geology}, volume = {114}, journal = {Economic geology}, number = {3}, publisher = {The Economic Geology Publ. Co}, address = {Littleton}, issn = {0361-0128}, doi = {10.5382/econgeo.4641}, pages = {569 -- 590}, year = {2019}, abstract = {Small-scale variations in mineral chemistry, textures, and platinum group element (PGE) mineralization were investigated in the Lower and Middle Group chromitite layers LG6, LG6a, MG1, MG2, and MG2 II from vertical drill core profiles at the Thaba mine in the northwestern limb of the Bushveld Complex. We present detailed geochemical profiles of chromite composition and chromite crystal size distribution curves to shed light on the processes of chromite accumulation and textural modification as well as mineralization. Multiple samples within each layer were assayed for PGE concentrations, and the respective platinum group mineral association was determined by mineral liberation analysis (MLA). There is strong evidence for postcumulus changes in the chromitites. The crystal size distribution curves suggest that the primary chromite texture was coarsened by a combination of adcumulus growth and textural equilibration, while compaction of the crystal mush played only a minor role. Mineral compositions were also modified by postcumulus processes, but because of the very high modal amount of chromite and its local preservation in orthopyroxene oikocrysts, that phase retained much primary information. Vertical variations of chromite composition within chromitite layers and from one layer to another do not support the idea of chromite accumulation from crystal-rich slurries or crystal settling from a large magma chamber. Instead, we favor a successive buildup of chromitite layers by repeated injections of relatively thin layers of chromite-saturated magmas, with in situ crystallization occurring at the crystal mush-magma interface. The adcumulus growth of chromite grains to form massive chromitite required addition of Cr to the layers, which we attribute to downward percolation from the overlying magma. The PGE concentrations are elevated in all chromitite layers compared to adjacent silicate rocks and show a systematic increase upward from LG6 (avg 807 ppb Ir + Ru + Rh + Pt + Pd + Au) to MG2 II (avg 2,062 ppb). There are also significant internal variations in all layers, with enrichments at hanging and/or footwalls. The enriched nature of chromitites in PGEs compared to host pyroxenites is a general feature, independent of the layer thickness. The MLA results distinguish two principal groups of PGE mineral associations: the LG6, LG6, and MG1 are dominated by the malanite series, laurite, and PGE sulfarsenides, while the MG2 and MG2 II layers are characterized by laurite and PGE sulfides as well as Pt-Fe-Sn and PGE-Sb-Bi-Pb alloys. Differences in the PGE associations are attributed to postcumulus alteration of the MG2 and MG2 II layer, while the chromitites below, particularly LG6 and LG6a, contain a more pristine association.}, language = {en} } @article{GarciaRoeserHoehle2019, author = {Garc{\´i}a, Rowena and Roeser, Jens and H{\"o}hle, Barbara}, title = {Thematic role assignment in the L1 acquisition of Tagalog}, series = {Language acquisition : a journal of developmental linguistics}, volume = {26}, journal = {Language acquisition : a journal of developmental linguistics}, number = {3}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {1048-9223}, doi = {10.1080/10489223.2018.1525613}, pages = {235 -- 261}, year = {2019}, abstract = {It is a common finding across languages that young children have problems in understanding patient-initial sentences. We used Tagalog, a verb-initial language with a reliable voice-marking system and highly frequent patient voice constructions, to test the predictions of several accounts that have been proposed to explain this difficulty: the frequency account, the Competition Model, and the incremental processing account. Study 1 presents an analysis of Tagalog child-directed speech, which showed that the dominant argument order is agent-before-patient and that morphosyntactic markers are highly valid cues to thematic role assignment. In Study 2, we used a combined self-paced listening and picture verification task to test how Tagalog-speaking adults and 5- and 7-year-old children process reversible transitive sentences. Results showed that adults performed well in all conditions, while children's accuracy and listening times for the first noun phrase indicated more difficulty in interpreting patient-initial sentences in the agent voice compared to the patient voice. The patient voice advantage is partly explained by both the frequency account and incremental processing account.}, language = {en} } @misc{Miklashevsky2019, author = {Miklashevsky, Alex A.}, title = {Words as social tools}, series = {Physics of life reviews}, volume = {29}, journal = {Physics of life reviews}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1571-0645}, doi = {10.1016/j.plrev.2019.04.002}, pages = {164 -- 165}, year = {2019}, language = {en} } @misc{vanLeeuwenKunschNergeretal.2019, author = {van Leeuwen, Peter Jan and Kunsch, Hans R. and Nerger, Lars and Potthast, Roland and Reich, Sebastian}, title = {Particle filters for high-dimensional geoscience applications: A review}, series = {Quarterly journal of the Royal Meteorological Society}, volume = {145}, journal = {Quarterly journal of the Royal Meteorological Society}, number = {723}, publisher = {Wiley}, address = {Hoboken}, issn = {0035-9009}, doi = {10.1002/qj.3551}, pages = {2335 -- 2365}, year = {2019}, abstract = {Particle filters contain the promise of fully nonlinear data assimilation. They have been applied in numerous science areas, including the geosciences, but their application to high-dimensional geoscience systems has been limited due to their inefficiency in high-dimensional systems in standard settings. However, huge progress has been made, and this limitation is disappearing fast due to recent developments in proposal densities, the use of ideas from (optimal) transportation, the use of localization and intelligent adaptive resampling strategies. Furthermore, powerful hybrids between particle filters and ensemble Kalman filters and variational methods have been developed. We present a state-of-the-art discussion of present efforts of developing particle filters for high-dimensional nonlinear geoscience state-estimation problems, with an emphasis on atmospheric and oceanic applications, including many new ideas, derivations and unifications, highlighting hidden connections, including pseudo-code, and generating a valuable tool and guide for the community. Initial experiments show that particle filters can be competitive with present-day methods for numerical weather prediction, suggesting that they will become mainstream soon.}, language = {en} } @article{BasaranDuyduUstundagetal.2019, author = {Basaran, Nursen and Duydu, Yalcin and Ustundag, Aylin and Taner, Gokce and Aydin, Sevtap and Anlar, Hatice Gul and Yalcin, Can {\"O}zg{\"u}r and Bacanli, Merve and Aydos, Kaan and Atabekoglu, Cem Somer and Golka, Klaus and Ickstadt, Katja and Schwerdtle, Tanja and Werner, Matthias and Meyer, S{\"o}ren and Bolt, Hermann M.}, title = {Evaluation of the DNA damage in lymphocytes, sperm and buccal cells of workers under environmental and occupational boron exposure conditions}, series = {Mutation Research/Genetic Toxicology and Environmental Mutagenesis}, volume = {843}, journal = {Mutation Research/Genetic Toxicology and Environmental Mutagenesis}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1383-5718}, doi = {10.1016/j.mrgentox.2018.12.013}, pages = {33 -- 39}, year = {2019}, abstract = {Industrial production and use of boron compounds have increased during the last decades, especially for the manufacture of borosilicate glass, fiberglass, metal alloys and flame retardants. This study was conducted in two districts of Balikesir; Bandirma and Bigadic, which geographically belong to the Marmara Region of Turkey. Bandirma is the production and exportation zone for the produced boric acid and some borates and Bigadic has the largest B deposits in Turkey. 102 male workers who were occupationally exposed to boron from Bandirma and 110 workers who were occupationally and environmentally exposed to boron from Bigadic participated to our study. In this study the DNA damage in the sperm, blood and buccal cells of 212 males was evaluated by comet and micronucleus assays. No significant increase in the DNA damage in blood, sperm and buccal cells was observed in the residents exposed to boron both occupationally and environmentally (p = 0.861) for Comet test in the sperm samples, p = 0.116 for Comet test in the lymphocyte samples, p = 0.042 for micronucleus (MN) test, p = 0.955 for binucleated cells (BN), p = 1.486 for condensed chromatin (CC), p = 0.455 for karyorrhectic cells (KHC), p = 0.541 for karyolitic cells (KLY), p = 1.057 for pyknotic cells (PHC), p = 0.331 for nuclear bud (NBUD)). No correlations were seen between blood boron levels and tail intensity values of the sperm samples, lymphocyte samples, frequencies of MN, BN, KHC, KYL, PHC and NBUD. The results of this study came to the same conclusions of the previous studies that boron does not induce DNA damage even under extreme exposure conditions.}, language = {en} } @article{RodriguezZuluagaStolleYamazakietal.2019, author = {Rodriguez-Zuluaga, Juan and Stolle, Claudia and Yamazaki, Yosuke and L{\"u}hr, H. and Park, J. and Scherliess, L. and Chau, J. L.}, title = {On the balance between plasma and magnetic pressure across equatorial plasma depletions}, series = {Journal of geophysical research : Space physics}, volume = {124}, journal = {Journal of geophysical research : Space physics}, number = {7}, publisher = {American Geophysical Union}, address = {Washington}, issn = {2169-9402}, doi = {10.1029/2019JA026700}, pages = {5936 -- 5944}, year = {2019}, abstract = {In magnetized plasmas such as the ionosphere, electric currents develop in regions of strong density gradients to balance the resulting plasma pressure gradients. These currents, usually known as diamagnetic currents decrease the magnetic pressure where the plasma pressure increases, and vice versa. In the low-latitude ionosphere, equatorial plasma depletions (EPDs) are well known for their steep plasma density gradients and adverse effect on radio wave propagation. In this paper, we use continuous measurements of the magnetic field and electron density from the European Space Agency's Swarm constellation mission to assess the balance between plasma and magnetic pressure across large-scale EPDs. The analysis is based on the magnetic fluctuations related to diamagnetic currents flowing at the edges of EPDs. This study shows that most of the EPDs detected by Swarm present a decrease of the plasma pressure relative to the ambient plasma. However, EPDs with high plasma pressure are also identified mainly in the vicinity of the South Atlantic magnetic anomaly. From the electron density measurements, we deduce that such an increase in plasma pressure within EPDs might be possible by temperatures inside the EPD as high as twice the temperature of the ambient plasma. Due to the distinct location of the high-pressure EPDs, we suggest that a possible heating mechanism might be due to precipitation of particle from the radiation belts. This finding corresponds to the first observational evidence of plasma pressure enhancements in regions of depleted plasma density in the ionosphere.}, language = {en} } @misc{MyachykovFischer2019, author = {Myachykov, Andriy and Fischer, Martin H.}, title = {A hierarchical view of abstractness}, series = {Physics of life reviews}, volume = {29}, journal = {Physics of life reviews}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1571-0645}, doi = {10.1016/j.plrev.2019.04.005}, pages = {161 -- 163}, year = {2019}, language = {en} } @article{vanderMeijReimannVornehmetal.2019, author = {van der Meij, Marijn W. and Reimann, Tony and Vornehm, V. K. and Temme, Arnaud J. A. M. and Wallinga, Jakob and van Beek, Roy and Sommer, Michael}, title = {Reconstructing rates and patterns of colluvial soil redistribution in agrarian (hummocky) landscapes}, series = {Earth surface processes and landforms : the journal of the British Geomorphological Research Group}, volume = {44}, journal = {Earth surface processes and landforms : the journal of the British Geomorphological Research Group}, number = {12}, publisher = {Wiley}, address = {Hoboken}, issn = {0197-9337}, doi = {10.1002/esp.4671}, pages = {2408 -- 2422}, year = {2019}, abstract = {Humans have triggered or accelerated erosion processes since prehistoric times through agricultural practices. Optically stimulated luminescence (OSL) is widely used to quantify phases and rates of the corresponding landscape change, by measuring the last moment of daylight exposure of sediments. However, natural and anthropogenic mixing processes, such as bioturbation and tillage, complicate the use of OSL as grains of different depositional ages become mixed, and grains become exposed to light even long after the depositional event of interest. Instead, OSL determines the stabilization age, indicating when sediments were buried below the active mixing zone. These stabilization ages can cause systematic underestimation when calculating deposition rates. Our focus is on colluvial deposition in a kettle hole in the Uckermark region, northeastern Germany. We took 32 samples from five locations in the colluvium filling the kettle hole to study both spatial and temporal patterns in colluviation. We combined OSL dating with advanced age modelling to determine the stabilization age of colluvial sediments. These ages were combined with an archaeological reconstruction of historical ploughing depths to derive the levels of the soil surface at the moment of stabilization; the deposition depths, which were then used to calculate unbiased deposition rates. We identified two phases of colluvial deposition. The oldest deposits (similar to 5 ka) were located at the fringe of the kettle hole and accumulated relatively slowly, whereas the youngest deposits (<0.3 ka) rapidly filled the central kettle hole with rates of two orders of magnitude higher. We suggest that the latter phase is related to artificial drainage, facilitating accessibility in the central depression for agricultural practices. Our results show the need for numerical dating techniques that take archaeological and soil-geomorphological information into account to identify spatiotemporal patterns of landscape change, and to correctly interpret landscape dynamics in anthropogenically influenced hilly landscapes. (c) 2019 The Authors. Earth Surface Processes and Landforms Published by John Wiley \& Sons Ltd.}, language = {en} }