@article{UnterhuberPovazayBizhevaetal.2004, author = {Unterhuber, Angelika and Povazay, B. and Bizheva, K. and Hermann, B. and Sattmann, Harald and Stingl, A. and Le, Trang and Seefeldt, Michael and Menzel, Ralf and Preusser, Matthias and Budka, Herbert and Schubert, Christian and Reitsamer, H. and Ahnelt, Peter Kurt and Morgan, J. E.}, title = {Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomography}, issn = {0031-9155}, year = {2004}, abstract = {Novel ultra-broad bandwidth light sources enabling unprecedented sub-2 pm axial resolution over the 400 nm-1700 nm wavelength range have been developed and evaluated with respect to their feasibility for clinical ultrahigh resolution optical coherence tomography (UHR OCT) applications. The state-of-the-art light sources described here include a compact Kerr lens mode locked Ti:sapphire laser (lambda(c) = 785 nm, Deltalambda = 260 nm, P-out = 50 mW) and different nonlinear fibre-based light sources with spectral bandwidths (at full width at half maximum) up to 350 nm at lambda(c) = 1130 nm and 470 nm at lambda(c) = 1375 run. In vitro UHR OCT imaging is demonstrated at multiple wavelengths in human cancer cells, animal ganglion cells as well as in neuropathologic and ophthalmic biopsies in order to compare and optimize UHR OCT image contrast, resolution and penetration depth}, language = {en} }