@article{MacdonaldMerzGuseetal.2022, author = {Macdonald, Elena and Merz, Bruno and Guse, Bj{\"o}rn and Wietzke, Luzie and Ullrich, Sophie and Kemter, Matthias and Ahrens, Bodo and Vorogushyn, Sergiy}, title = {Event and catchment controls of heavy tail behavior of floods}, series = {Water resources research}, volume = {58}, journal = {Water resources research}, number = {6}, publisher = {American Geophysical Union}, address = {Washington}, issn = {0043-1397}, doi = {10.1029/2021WR031260}, pages = {25}, year = {2022}, abstract = {In some catchments, the distribution of annual maximum streamflow shows heavy tail behavior, meaning the occurrence probability of extreme events is higher than if the upper tail decayed exponentially. Neglecting heavy tail behavior can lead to an underestimation of the likelihood of extreme floods and the associated risk. Partly contradictory results regarding the controls of heavy tail behavior exist in the literature and the knowledge is still very dispersed and limited. To better understand the drivers, we analyze the upper tail behavior and its controls for 480 catchments in Germany and Austria over a period of more than 50 years. The catchments span from quickly reacting mountain catchments to large lowland catchments, allowing for general conclusions. We compile a wide range of event and catchment characteristics and investigate their association with an indicator of the tail heaviness of flood distributions, namely the shape parameter of the GEV distribution. Following univariate analyses of these characteristics, along with an evaluation of different aggregations of event characteristics, multiple linear regression models, as well as random forests, are constructed. A novel slope indicator, which represents the relation between the return period of flood peaks and event characteristics, captures the controls of heavy tails best. Variables describing the catchment response are found to dominate the heavy tail behavior, followed by event precipitation, flood seasonality, and catchment size. The pre-event moisture state in a catchment has no relevant impact on the tail heaviness even though it does influence flood magnitudes.}, language = {en} } @article{AshtonDietrich2022, author = {Ashton, Gregory and Dietrich, Tim}, title = {The use of hypermodels to understand binary neutron star collisions}, series = {Nature astronomy}, volume = {6}, journal = {Nature astronomy}, number = {8}, publisher = {Nature portfolio}, address = {Berlin}, issn = {2397-3366}, doi = {10.1038/s41550-022-01707-x}, pages = {961 -- 967}, year = {2022}, abstract = {Gravitational waves from the collision of binary neutron stars provide a unique opportunity to study the behaviour of supranuclear matter, the fundamental properties of gravity and the cosmic history of our Universe. However, given the complexity of Einstein's field equations, theoretical models that enable source-property inference suffer from systematic uncertainties due to simplifying assumptions. We develop a hypermodel approach to compare and measure the uncertainty of gravitational-wave approximants. Using state-of-the-art models, we apply this new technique to the binary neutron star observations GW170817 and GW190425 and to the sub-threshold candidate GW200311_103121. Our analysis reveals subtle systematic differences (with Bayesian odds of similar to 2) between waveform models. A frequency-dependence study suggests that this may be due to the treatment of the tidal sector. This new technique provides a proving ground for model development and a means to identify waveform systematics in future observing runs where detector improvements will increase the number and clarity of binary neutron star collisions we observe.}, language = {en} } @article{MazzoneWachsFoodyetal.2022, author = {Mazzone, Angela and Wachs, Sebastian and Foody, Mairead and Blaya, Catherine}, title = {Editorial: A connected or isolated generation?}, series = {Frontiers in education}, volume = {7}, journal = {Frontiers in education}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {2504-284X}, doi = {10.3389/feduc.2022.999028}, pages = {3}, year = {2022}, language = {en} } @techreport{Franzke2021, author = {Franzke, Jochen}, title = {Das Zusammenwirken der Ortsbeir{\"a}te mit der Stadtverwaltung und der Stadtverordnetenversammlung}, editor = {Landeshauptstadt Potsdam, Oberb{\"u}rgermeister}, publisher = {Landeshauptstadt Potsdam}, address = {Potsdam}, pages = {27}, year = {2021}, language = {de} } @inproceedings{OPUS4-63603, title = {Plattformen : Grundlagen und Neuordnung des Rechts digitaler Plattformen}, editor = {Buchheim, Johannes and Kraetzig, Viktoria and Mendelsohn, Juliane and Steinr{\"o}tter, Bj{\"o}rn}, publisher = {Nomos}, address = {Baden-Baden}, isbn = {978-3-7560-1454-5}, pages = {263}, year = {2024}, abstract = {Digitale Plattformen pr{\"a}gen unsere Rechts- und Wirtschaftsordnung, die Freizeitgestaltung, das Informationsverhalten und im Aggregat die digitale {\"O}ffentlichkeit. Die damit verbundenen Rechtsfragen sind im Fluss und ber{\"u}hren alle juristischen Teildisziplinen. Der Tagungsband n{\"a}hert sich daher den Entwicklungen des Plattformrechts aus disziplin{\"u}bergreifendem Blickwinkel. Dieser Versuch einer {\"u}berspannenden Perspektive fokussiert vor allem auf die beiden „Großen" der j{\"u}ngsten Rechtsakte (DSA/DMA) unter dem besonderen Gesichtspunkt ihres Vollzugs: Wie kann man ein globales Ph{\"a}nomen wie Plattformen lokal und regional regulieren? Welche Rolle spielt der Schwarm der Vielen in der Effektivierung der neuen Regularien? Passen Regelungsmodelle wie das Urheberrecht zum Plattformph{\"a}nomen?}, language = {de} } @techreport{Franzke2022, author = {Franzke, Jochen}, title = {„Brandenburger St{\"a}dte und Gemeinden in der Lausitz. Transformationsherausforderungen und Anpassungsstrategien an den regionalen Strukturwandel"}, editor = {Fraktion B{\"U}NDNIS 90/DIE GR{\"U}NEN,}, publisher = {Fraktion B{\"U}NDNIS 90/DIE GR{\"U}NEN}, address = {Potsdam}, pages = {62}, year = {2022}, abstract = {Seit zwei Jahren arbeiten die Werkst{\"a}tten der Wirtschaftsregion Lausitz an der Projektauswahl und -qualifizierung f{\"u}r die Strukturst{\"a}rkungsmittel. Wir haben uns gefragt: Wie geht es Vertreter*innen aus Lausitzer St{\"a}dten und Gemeinden auf diesem Neuland? Was brauchen sie, um der zentralen Rolle gerecht zu werden, die das Strukturst{\"a}rkungsgesetz f{\"u}r sie vorgesehen hat? Und wo k{\"o}nnen wir als politische Vertreter*innen aktiv werden, um Hindernisse aus dem Weg zu r{\"a}umen? Daf{\"u}r ist Prof. Dr. Franzke in den letzten Monaten mit Lausitzer*innen ins Gespr{\"a}ch gekommen. Der vorliegende Bericht soll - als Momentaufnahme - erste Antworten liefern. Wir stehen am Anfang eines langandauernden Transformationsprozesses. Auf manche Fragen gibt es noch keine Antworten und auf andere wird sich die Antwort im Laufe der Zeit wom{\"o}glich {\"a}ndern. Das ist auch in Ordnung. Denn in einem sich stetig wandelnden Prozess lernen wir, mit sich stetig wandelnden Antworten zu leben.}, language = {de} } @article{BorghiShakiFischer2022, author = {Borghi, Anna M. and Shaki, Samuel and Fischer, Martin H.}, title = {Abstract concepts: external influences, internal constraints, and methodological issues}, series = {Psychological research : an international journal of perception, attention, memory, and action}, volume = {86}, journal = {Psychological research : an international journal of perception, attention, memory, and action}, publisher = {Springer}, address = {Heidelberg}, issn = {0340-0727}, doi = {10.1007/s00426-022-01698-4}, pages = {2370 -- 2388}, year = {2022}, abstract = {There is a longstanding and widely held misconception about the relative remoteness of abstract concepts from concrete experiences. This review examines the current evidence for external influences and internal constraints on the processing, representation, and use of abstract concepts, like truth, friendship, and number. We highlight the theoretical benefit of distinguishing between grounded and embodied cognition and then ask which roles do perception, action, language, and social interaction play in acquiring, representing and using abstract concepts. By reviewing several studies, we show that they are, against the accepted definition, not detached from perception and action. Focussing on magnitude-related concepts, we also discuss evidence for cultural influences on abstract knowledge and explore how internal processes such as inner speech, metacognition, and inner bodily signals (interoception) influence the acquisition and retrieval of abstract knowledge. Finally, we discuss some methodological developments. Specifically, we focus on the importance of studies that investigate the time course of conceptual processing and we argue that, because of the paramount role of sociality for abstract concepts, new methods are necessary to study concepts in interactive situations. We conclude that bodily, linguistic, and social constraints provide important theoretical limitations for our theories of conceptual knowledge.}, language = {en} } @article{NakoudiStachlewskaRitter2021, author = {Nakoudi, Konstantina and Stachlewska, Iwona S. and Ritter, Christoph}, title = {An extended lidar-based cirrus cloud retrieval scheme}, series = {Optics express : the international electronic journal of optics / Optica}, volume = {29}, journal = {Optics express : the international electronic journal of optics / Optica}, number = {6}, publisher = {Optical Society of America}, address = {Washington}, issn = {1094-4087}, doi = {10.1364/OE.414770}, pages = {8553 -- 8580}, year = {2021}, abstract = {Accurate and precise characterization of cirrus cloud geometrical and optical properties is essential for better constraining their radiative footprint. A lidar-based retrieval scheme is proposed here, with its performance assessed on fine spatio-temporal observations over the Arctic site of Ny-Alesund, Svalbard. Two contributions related to cirrus geometrical (dynamic Wavelet Covariance Transform (WCT)) and optical properties (constrained Klett) are reported. The dynamic WCT rendered cirrus detection more robust, especially for thin cirrus layers that frequently remained undetected by the classical WCT method. Regarding optical characterization, we developed an iterative scheme for determining the cirrus lidar ratio (LRci) that is a crucial parameter for aerosol - cloud discrimination. Building upon the Klett-Fernald method, the LRci was constrained by an additional reference value. In established methods, such as the double-ended Klett, an aerosol-free reference value is applied. In the proposed constrained Klett, however, the reference value was approximated from cloud-free or low cloud optical depth (COD up to 0.2) profiles and proved to agree with independent Raman estimates. For optically thin cirrus, the constrained Klett inherent uncertainties reached 50\% (60-74\%) in terms of COD (LRci). However, for opaque cirrus COD (LRci) uncertainties were lower than 10\% (15\%). The detection method discrepancies (dynamic versus static WCT) had a higher impact on the optical properties of low COD layers (up to 90\%) compared to optically thicker ones (less than 10\%). The constrained Klett presented high agreement with two established retrievals. For an exemplary cirrus cloud, the constrained Klett estimated the COD355 (LRci355) at 0.28 +/- 0.17 (29 +/- 4 sr), the double-ended Klett at 0.27 +/- 0.15 (32 +/- 4 sr) and the Raman retrievals at 0.22 +/- 0.12 (26 +/- 11 sr). Our approach to determine the necessary reference value can also be applied in established methods and increase their accuracy. In contrast, the classical aerosol-free assumption led to 44 sr LRci overestimation in optically thin layers and 2-8 sr in thicker ones. The multiple scattering effect was corrected using Eloranta (1998) and accounted for 50-60\% extinction underestimation near the cloud base and 20-30\% within the cirrus layers.}, language = {en} } @misc{DuevelEhmigMcCalletal.2024, author = {D{\"u}vel, Pia and Ehmig, Ulrike and McCall, Jeremiah and Unceta G{\´o}mez, Luis and Bakogianni, Anastasia and Fischer, Jens and Serrano Lozano, David and Amb{\"u}hl, Annemarie and Matz, Alicia and Brinker, Wolfram and Mach, Jonas Konstantin and Mancini, Mattia and Werner, Eva}, title = {Spring Issue}, series = {thersites}, volume = {2024}, journal = {thersites}, number = {18}, editor = {Amb{\"u}hl, Annemarie and Carl{\`a}-Uhink, Filippo and Rollinger, Christian and Walde, Christine}, issn = {2364-7612}, doi = {10.34679/thersites.vol18}, year = {2024}, language = {en} } @article{SchultzeWirthWunderetal.2021, author = {Schultze, Dina and Wirth, Richard and Wunder, Bernd and Loges, Anselm and Wilke, Max and Franz, Gerhard}, title = {Corundum-quartz metastability}, series = {Contributions to mineralogy and petrology}, volume = {176}, journal = {Contributions to mineralogy and petrology}, number = {4}, publisher = {Springer}, address = {Berlin ; Heidelberg}, issn = {0010-7999}, doi = {10.1007/s00410-021-01786-5}, pages = {13}, year = {2021}, abstract = {The metastable paragenesis of corundum and quartz is rare in nature but common in laboratory experiments where according to thermodynamic predictions aluminum-silicate polymorphs should form. We demonstrate here that the existence of a hydrous, silicon-bearing, nanometer-thick layer (called "HSNL") on the corundum surface can explain this metastability in experimental studies without invoking unspecific kinetic inhibition. We investigated experimentally formed corundum reaction products synthesized during hydrothermal and piston-cylinder experiments at 500-800 degrees C and 0.25-1.8 GPa and found that this HSNL formed inside and on the corundum crystals, thereby controlling the growth behavior of its host. The HSNL represents a substitution of Al with Si and H along the basal plane of corundum. Along the interface of corundum and quartz, the HSNL effectively isolates the bulk phases corundum and quartz from each other, thus apparently preventing their reaction to the stable aluminum silicate. High temperatures and prolonged experimental duration lead to recrystallization of corundum including the HSNL and to the formation of quartz + fluid inclusions inside the host crystal. This process reduces the phase boundary area between the bulk phases, thereby providing further opportunity to expand their coexistence. In addition to its small size, its transient nature makes it difficult to detect the HSNL in experiments and even more so in natural samples. Our findings emphasize the potential impact of nanometer-sized phases on geochemical reaction pathways and kinetics under metamorphic conditions in one of the most important chemical systems of the Earth's crust.}, language = {en} } @article{HoffmannOttRaupbachetal.2022, author = {Hoffmann, Holger and Ott, Christiane and Raupbach, Jana and Andernach, Lars and Renz, Matthias and Grune, Tilman and Hanschen, Franziska S.}, title = {Assessing bioavailability and bioactivity of 4-Hydroxythiazolidine-2-Thiones, newly discovered glucosinolate degradation products formed during domestic boiling of cabbage}, series = {Frontiers in nutrition}, volume = {9}, journal = {Frontiers in nutrition}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {2296-861X}, doi = {10.3389/fnut.2022.941286}, pages = {13}, year = {2022}, abstract = {Glucosinolates are plant secondary metabolites found in cruciferous vegetables (Brassicaceae) that are valued for their potential health benefits. Frequently consumed representatives of these vegetables, for example, are white or red cabbage, which are typically boiled before consumption. Recently, 3-alk(en)yl-4-hydroxythiazolidine-2-thiones were identified as a class of thermal glucosinolate degradation products that are formed during the boiling of cabbage. Since these newly discovered compounds are frequently consumed, this raises questions about their potential uptake and their possible bioactive functions. Therefore, 3-allyl-4-hydroxythiazolidine-2-thione (allyl HTT) and 4-hydroxy-3-(4-(methylsulfinyl) butyl)thiazolidine-2-thione (4-MSOB HTT) as degradation products of the respective glucosinolates sinigrin and glucoraphanin were investigated. After consumption of boiled red cabbage broth, recoveries of consumed amounts of the degradation products in urine collected for 24 h were 18 +/- 5\% for allyl HTT and 21 +/- 4\% for 4-MSOB HTT (mean +/- SD, n = 3). To investigate the stability of the degradation products during uptake and to elucidate the uptake mechanism, both an in vitro stomach and an in vitro intestinal model were applied. The results indicate that the uptake of allyl HTT and 4-MSOB HTT occurs by passive diffusion. Both compounds show no acute cell toxicity, no antioxidant potential, and no change in NAD(P)H dehydrogenase quinone 1 (NQO1) activity up to 100 mu M. However, inhibition of glycogen synthase kinases-3 (GSK-3) in the range of 20\% for allyl HTT for the isoform GSK-3 beta and 29\% for 4-MSOB HTT for the isoform GSK-3 alpha at a concentration of 100 mu M was found. Neither health-promoting nor toxic effects of 3-alk(en)yl-4-hydroxythiazolidine-2-thiones were found in the four tested assays carried out in this study, which contrasts with the properties of other glucosinolate degradation products, such as isothiocyanates.}, language = {en} } @article{JamalreyhaniRezapourCescaetal.2022, author = {Jamalreyhani, Mohammadreza and Rezapour, Mehdi and Cesca, Simone and Dahm, Torsten and Heimann, Sebastian and Sudhaus, Henriette and Isken, Marius Paul}, title = {Insight into the 2017-2019 Lurestan arc seismic sequence (Zagros, Iran); complex earthquake interaction in the basement and sediments}, series = {Geophysical journal international}, volume = {230}, journal = {Geophysical journal international}, number = {1}, publisher = {Oxford Univ. Press}, address = {Oxford}, issn = {0956-540X}, doi = {10.1093/gji/ggac057}, pages = {114 -- 130}, year = {2022}, abstract = {Despite its high-seismogenic potential, the details of the seismogenic processes of Zagros Simply Folded Belt (SFB) remains debated. Three large earthquakes (M-w 7.3, 5.9 and 6.3) struck in the Lurestan arc of the Zagros SFB in 2017 and 2018. The sequence was recorded by seismic stations at regional, and teleseismic distances. Coseismic surface displacements, measured by Sentinel-1A/B satellites, provide additional data and a unique opportunity to study these earthquakes in detail. Here, we complement previous studies of the coseismic slip distribution of the 12 November 2017 M-w 7.3 Ezgeleh earthquake by a detailed analysis of its aftershocks, and we analysed the rupture process of the two interrelated earthquakes (25 August 2018 M-w 5.9 Tazehabad and the 25 November 2018 M-w 6.3 Sarpol-e Zahab earthquakes). We model the surface displacements obtained from Interferometric Synthetic Aperture Radar (InSAR) measurements and seismic records. We conduct non-linear probabilistic optimizations based on joint InSAR and seismic data to obtain finite-fault rupture of these earthquakes. The Lurestan arc earthquakes were followed by a sustained aftershock activity, with 133 aftershocks exceeding M-n 4.0 until 30 December 2019. We rely on the permanent seismic networks of Iran and Iraq to relocate similar to 700 M-n 3 + events and estimate moment tensor solutions for 85 aftershocks down to M-w 4.0. The 2017 Ezgeleh earthquake has been considered to activate a low-angle (similar to 17 degrees) dextral-thrust fault at the depth of 10-20 km. However, most of its aftershocks have shallow centroid depths (8-12 km). The joint interpretation of finite source models, moment tensor and hypocentral location indicate that the 2018 Tazehabad and Sarpol-e Zahab earthquakes ruptured different strike-slip structures, providing evidence for the activation of the sinistral and dextral strike-slip faults, respectively. The deformation in the Lurestan arc is seismically accommodated by a complex fault system involving both thrust and strike-slip faults. Knowledge about the deformation characteristics is important for the understanding of crustal shortening, faulting and hazard and risk assessment in this region.}, language = {en} } @article{RamosLariosToalaRodriguezGonzalezetal.2022, author = {Ramos-Larios, Gerardo and Toala, Jes{\´u}s Alberto and Rodriguez-Gonzalez, Janis B. and Guerrero, Martin A. and Gomez-Gonzalez, V{\´i}ctor Mauricio Alfonso}, title = {Rings and arcs around evolved stars - III. Physical conditions of the ring-like structures in the planetary nebula IC 4406 revealed by MUSE}, series = {Monthly notices of the Royal Astronomical Society}, volume = {513}, journal = {Monthly notices of the Royal Astronomical Society}, number = {2}, publisher = {Oxford Univ. Press}, address = {Oxford}, issn = {0035-8711}, pages = {2862 -- 2868}, year = {2022}, abstract = {We present the analysis of Very Large Telescope Multi Unit Spectroscopic Explorer (MUSE) observations of the planetary nebula (PN) IC 4406. MUSE images in key emission lines are used to unveil the presence of at least five ring-like structures north and south of the main nebula of IC4406. MUSE spectra are extracted from the rings to unambiguously assess for the first time in a PN their physical conditions, electron density (n(e)), and temperature (T-e). The rings are found to have similar T-e as the rim of the main nebula, but smaller n(e). Ratios between different ionic species suggest that the rings of IC4406 have a lower ionization state than the main cavity, in contrast to what was suggested for the rings in NGC 6543, the Cat's Eye Nebula.}, language = {en} } @article{DworkinKraheZinzow2021, author = {Dworkin, Emily R. and Krah{\´e}, Barbara and Zinzow, Heidi}, title = {The global prevalence of sexual assault}, series = {Psychology of violence}, volume = {11}, journal = {Psychology of violence}, number = {5}, publisher = {American Psychological Association}, address = {Washington}, issn = {2152-0828}, doi = {10.1037/vio0000374}, pages = {497 -- 508}, year = {2021}, abstract = {Objective: We present a review of peer-reviewed English-language studies conducted outside the United States and Canada on the prevalence of sexual assault victimization in adolescence and adulthood published since 2010. Method: A systematic literature search yielded 32 articles reporting on 45 studies from 29 countries. Studies that only provided prevalence estimates for sexual assault in intimate relationships or did not present separate rates for men and women were excluded. All studies were coded by two coders, and a risk of bias score was calculated for each study. Both past-year and prevalence rates covering longer periods were extracted. Results: The largest number of studies came from Europe (n = 21), followed by Africa (n = 11), Asia, and Latin America (n = 6 each). One study came from the Middle East and no studies were found from Oceania. Across the 22 studies that reported past-year prevalence rates, figures ranged from 0\% to 59.2\% for women, 0.3\% to 55.5\% for men, and 1.5\% to 18.2\% for lesbian, gay, bisexual, and transgender (LGBT) samples. The average risk of bias score was 5.7 out of 10. Studies varied widely in methodology. Conclusion: Despite regional variation, most studies indicate that sexual assault is widespread. More sustained, systematic, and coordinated research efforts are needed to gauge the scale of sexual assault in different parts of the world and to develop prevention measures.}, language = {en} } @article{HartmannLangArneth2023, author = {Hartmann, Eddie and Lang, Felix and Arneth, Sabrina}, title = {Eskalation in Tweets}, series = {Schriftenreihe der Bundeszentrale f{\"u}r politische Bildung}, volume = {11043}, journal = {Schriftenreihe der Bundeszentrale f{\"u}r politische Bildung}, publisher = {Bundeszentrale f{\"u}r politische Bildung}, address = {Bonn}, isbn = {978-3-7425-1043-3}, pages = {108 -- 118}, year = {2023}, language = {de} } @article{MelchertWischhoeferKnoblauchetal.2022, author = {Melchert, Jan Olaf and Wischh{\"o}fer, Philipp and Knoblauch, Christian and Eckhardt, Tim and Liebner, Susanne and Rethemeyer, Janet}, title = {Sources of CO2 Produced in Freshly Thawed Pleistocene-Age Yedoma Permafrost}, series = {Frontiers in Earth Science}, volume = {9}, journal = {Frontiers in Earth Science}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {2296-6463}, doi = {10.3389/feart.2021.737237}, pages = {13}, year = {2022}, abstract = {The release of greenhouse gases from the large organic carbon stock in permafrost deposits in the circumarctic regions may accelerate global warming upon thaw. The extent of this positive climate feedback is thought to be largely controlled by the microbial degradability of the organic matter preserved in these sediments. In addition, weathering and oxidation processes may release inorganic carbon preserved in permafrost sediments as CO2, which is generally not accounted for. We used C-13 and C-14 analysis and isotopic mass balances to differentiate and quantify organic and inorganic carbon released as CO2 in the field from an active retrogressive thaw slump of Pleistocene-age Yedoma and during a 1.5-years incubation experiment. The results reveal that the dominant source of the CO2 released from freshly thawed Yedoma exposed as thaw mound is Pleistocene-age organic matter (48-80\%) and to a lesser extent modern organic substrate (3-34\%). A significant portion of the CO2 originated from inorganic carbon in the Yedoma (17-26\%). The mixing of young, active layer material with Yedoma at a site on the slump floor led to the preferential mineralization of this young organic carbon source. Admixtures of younger organic substrates in the Yedoma thaw mound were small and thus rapidly consumed as shown by lower contributions to the CO2 produced during few weeks of aerobic incubation at 4 degrees C corresponding to approximately one thaw season. Future CO2 fluxes from the freshly thawed Yedoma will contain higher proportions of ancient inorganic (22\%) and organic carbon (61-78\%) as suggested by the results at the end, after 1.5 years of incubation. The increasing contribution of inorganic carbon during the incubation is favored by the accumulation of organic acids from microbial organic matter degradation resulting in lower pH values and, in consequence, in inorganic carbon dissolution. Because part of the inorganic carbon pool is assumed to be of pedogenic origin, these emissions would ultimately not alter carbon budgets. The results of this study highlight the preferential degradation of younger organic substrates in freshly thawed Yedoma, if available, and a substantial release of CO2 from inorganic sources.}, language = {en} } @article{CrucesZabalaRitterWeckmannetal.2022, author = {Cruces-Zabala, Jos{\´e} Alejandro and Ritter, Oliver and Weckmann, Ute and Tietze, Kristina and Meqbel, Naser M. and Audemard, Franck and Schmitz, Michael}, title = {Three-dimensional magnetotelluric imaging of the Merida Andes, Venezuela}, series = {Journal of South American earth sciences}, volume = {114}, journal = {Journal of South American earth sciences}, publisher = {Elsevier}, address = {Oxford}, issn = {0895-9811}, doi = {10.1016/j.jsames.2022.103711}, pages = {17}, year = {2022}, abstract = {The 100 km wide Merida Andes extend from the Colombian/Venezuelan border to the Coastal Cordillera. The mountain chain and its associated major strike-slip fault systems in western Venezuela formed due to oblique convergence of the Caribbean with the South American Plates and the north-eastwards expulsion of the North Andean Block. Due to the limited knowledge of lithospheric structures related to the formation of the Merida Andes research projects have been developed to illuminate this zone with deep geophysical data. In this study, we present three-dimensional inversion of broadband magnetotelluric data, collected along a 240 km long profile crossing the Merida Andes and the Maracaibo and Barinas-Apure foreland basins. The distribution of the stations limits resolution of the model to off-profile features. Combining 3D inversion of synthetic data sets derived from 3D modelling with 3D inversion of measured data, we could derive a 10 to 15 km wide corridor with good lateral resolution to develop hypotheses about the origin of deep-reaching anomalies of high electrical conductivity. The Merida Andes appear generally as electrically resistive structures, separated by anomalies associated with the most important fault systems of the region, the Bocono and Valera faults. Sensitivity tests suggest that the Valera Fault reaches to depths of up to 12 km and the Bocono Fault to more than 35 km depth. Both structures are connected to a sizeable conductor located east of the profile at 12-15 km depth. We propose that the high conductivity associated with this off-profile conductor may be related to the detachment of the Trujillo Block. We also identified a conductive zone that correlates spatially with the location of a gravity low, possibly representing a SE tilt of the Maracaibo Triangular Block under the mountain chain to great depths (>30 km). The relevance of these tectonic blocks in our models at crustal depths seems to be consistent with proposed theories that describe the geodynamics of western Venezuela as dominated by floating blocks or orogens. Our results stress the importance of the Trujillo Block for the current tectonic evolution of western Venezuela and confirm the relevance of the Bocono Fault carrying deformation to the lower crust and upper mantle. The Barinas-Apure and the Maracaibo sedimentary basins are imaged as electrically conductive with depths of 4 to 5 km and 5 to 10 km, respectively. The Barinas-Apure basin is imaged as a simple 1D structure, in contrast to the Maracaibo Basin, where a series of conductive and resistive bodies could be related to active deformation causing the juxtaposition of older geological formations and younger basin sediments.}, language = {en} } @article{DreymannWuenscheSabrowskietal.2022, author = {Dreymann, Nico and Wuensche, Julia and Sabrowski, Wiebke and Moeller, Anja and Czepluch, Denise and Vu Van, Dana and F{\"u}ssel, Susanne and Menger, Marcus M.}, title = {Inhibition of Human Urokinase-Type Plasminogen Activator (uPA) Enzyme Activity and Receptor Binding by DNA Aptamers as Potential Therapeutics through Binding to the Different Forms of uPA}, series = {International journal of molecular sciences}, volume = {23}, journal = {International journal of molecular sciences}, number = {9}, publisher = {MDPI}, address = {Basel}, issn = {1661-6596}, doi = {10.3390/ijms23094890}, pages = {22}, year = {2022}, abstract = {Urokinase-type plasminogen activator is widely discussed as a marker for cancer prognosis and diagnosis and as a target for cancer therapies. Together with its receptor, uPA plays an important role in tumorigenesis, tumor progression and metastasis. In the present study, systematic evolution of ligands by exponential enrichment (SELEX) was used to select single-stranded DNA aptamers targeting different forms of human uPA. Selected aptamers allowed the distinction between HMW-uPA and LMW-uPA, and therefore, presumably, have different binding regions. Here, uPAapt-02-FR showed highly affine binding with a K-D of 0.7 nM for HMW-uPA and 21 nM for LMW-uPA and was also able to bind to pro-uPA with a K-D of 14 nM. Furthermore, no cross-reactivity to mouse uPA or tissue-type plasminogen activator (tPA) was measured, demonstrating high specificity. Suppression of the catalytic activity of uPA and inhibition of uPAR-binding could be demonstrated through binding with different aptamers and several of their truncated variants. Since RNA aptamers are already known to inhibit uPA-uPAR binding and other pathological functions of the uPA system, these aptamers represent a novel, promising tool not only for detection of uPA but also for interfering with the pathological functions of the uPA system by additionally inhibiting uPA activity.}, language = {en} } @article{JuangSchachnerAraletal.2023, author = {Juang, Linda P. and Schachner, Maja and Aral, Tuğ{\c{c}}e and Schwarzenthal, Miriam and Kunyu, David Khisoni and L{\"o}hmannsr{\"o}ben, Hanna}, title = {Effects of a brief self-affirmation writing intervention among 7(th) graders in Germany}, series = {Social psychology of education : an international journal}, journal = {Social psychology of education : an international journal}, publisher = {Springer}, address = {Dordrecht}, issn = {1381-2890}, doi = {10.1007/s11218-023-09789-9}, pages = {35}, year = {2023}, abstract = {We tested whether a brief self-affirmation writing intervention protected against identity-threats (i.e., stereotyping and discrimination) for adolescents' school-related adjustment. The longitudinal study followed 639 adolescents in Germany (65\% of immigrant descent, 50\% female, M-age = 12.35 years, SDage = .69) from 7(th) grade (pre-intervention at T1, five to six months post-intervention at T2) to the end of 8(th) grade (one-year follow-up at T3). We tested for direct and moderated (by heritage group, discrimination, classroom cultural diversity climate) effects using regression and latent change models. The self-affirmation intervention did not promote grades or math competence. However, in the short-term and for adolescents of immigrant descent, the intervention prevented a downward trajectory in mastery reactions to academic challenges for those experiencing greater discrimination. Further, it protected against a decline in behavioral school engagement for those in positive classroom cultural diversity climates. In the long-term and for all adolescents, the intervention lessened an upward trajectory in disruptive behavior. Overall, the self-affirmation intervention benefited some aspects of school-related adjustment for adolescents of immigrant and non-immigrant descent. The intervention context is important, with classroom cultural diversity climate acting as a psychological affordance enhancing affirmation effects. Our study supports the ongoing call for theorizing and empirically testing student and context heterogeneity to better understand for whom and under which conditions this intervention may work.}, language = {en} } @article{ValenzuelaMalebranCescaLopezCominoetal.2022, author = {Valenzuela-Malebran, Carla and Cesca, Simone and Lopez-Comino, Jos{\´e} {\´A}ngel and Zeckra, Martin and Kr{\"u}ger, F. and Dahm, Torsten}, title = {Source mechanisms and rupture processes of the Jujuy seismic nest, Chile-Argentina border}, series = {Journal of South American earth sciences}, volume = {117}, journal = {Journal of South American earth sciences}, publisher = {Elsevier}, address = {Oxford}, issn = {0895-9811}, doi = {10.1016/j.jsames.2022.103887}, pages = {13}, year = {2022}, abstract = {The Altiplano-Puna plateau, in Central Andes, is the second-largest continental plateau on Earth, extending between 22 degrees and 27 degrees S at an average altitude of 4400 m. The Puna plateau has been formed in consequence of the subduction of the oceanic Nazca Plate beneath the continental South American plate, which has an average crustal thickness of 50 km at this location. A large seismicity cluster, the Jujuy cluster, is observed at depth of 150-250 km beneath the central region of the Puna plateau. The cluster is seismically very active, with hundreds of earthquakes reported and a peak magnitude MW 6.6 on 25th August 2006. The cluster is situated in one of three band of intermediate-depth focus seismicity, which extend parallel to the trench roughly North to South. It has been hypothesized that the Jujuy cluster could be a seismic nest, a compact seismogenic region characterized by a high stationary activity relative to its surroundings. In this study, we collected more than 40 years of data from different catalogs and proof that the cluster meets the three conditions of a seismic nest. Compared to other known intermediate depth nests at Hindu Kush (Afganisthan) or Bucaramanga (Colombia), the Jujuy nest presents an outstanding seismicity rate, with more than 100 M4+ earthquakes per year. We additionally performed a detailed analysis of the rupture process of some of the largest earthquakes in the nest, by means of moment tensor inversion and directivity analysis. We focused on the time period 2017-2018, where the seismic monitoring was the most extended. Our results show that earthquakes in the nest take place within the eastward subducting oceanic plate, but rupture along sub-horizontal planes dipping westward. We suggest that seismicity at Jujuy nest is controlled by dehydration processes, which are also responsible for the generation of fluids ascending to the crust beneath the Puna volcanic region. We use the rupture plane and nest geometry to provide a constraint to maximal expected magnitude, which we estimate as MW -6.7.}, language = {en} }