@phdthesis{Eckert2019,
  author    = {Eckert, Sebastian},
  title     = {Accessing active sites of molecular proton dynamics},
  doi       = {10.25932/publishup-42587},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-425870},
  school      = {Universit{\"a}t Potsdam},
  pages     = {xviii, 193},
  year      = {2019},
  abstract  = {The unceasing impact of intense sunlight on earth constitutes a continuous source of energy fueling countless natural processes. On a molecular level, the energy contained in the electromagnetic radiation is transferred through photochemical processes into chemical or thermal energy. In the course of such processes, photo-excitations promote molecules into thermally inaccessible excited states. This induces adaptations of their molecular geometry according to the properties of the excited state. Decay processes towards energetically lower lying states in transient molecular geometries result in the formation of excited state relaxation pathways. The photo-chemical relaxation mechanisms depend on the studied system itself, the interactions with its chemical environment and the character of the involved states. This thesis focuses on systems in which photo-induced deprotonation processes occur at specific atomic sites. To detect these excited-state proton dynamics at the affected atoms, a local probe of molecular electronic structure is required. Therefore, site-selective and orbital-specific K-edge soft X-ray spectroscopy techniques are used here to detect photo-induced proton dynamics in gaseous and liquid sample environments. The protonation of nitrogen (N) sites in organic molecules and the oxygen (O) atom in the water molecule are probed locally through transitions between 1s orbitals and the p-derived molecular valence electronic structure. The used techniques are X-ray absorption spectroscopy (XAS) and resonant inelastic X-ray scattering (RIXS). Both yield access to the unoccupied local valence electronic structure, whereas the latter additionally probes occupied states. We apply these probes in optical pump X-ray probe experiments to investigate valence excited-state proton transfer capabilities of aqueous 2-thiopyridone. A characteristic shift of N K-edge X-ray absorption resonances as well as a distinct X-ray emission line are established by us as spectral fingerprints of N deprotonation in the system. We utilize them to identify photo-induced N deprotonation of 2-thiopyridone on femtosecond timescales, in optical pump N K-edge RIXS probe measurements. We further establish excited state proton transfer mechanisms on picosecond and nanosecond timescales along the dominant relaxation pathways of 2-thiopyridone using transient N K-edge XAS. Despite being an excellent probe mechanism for valence excited-state proton dynamics, the K-edge core-excitation itself also disturbs the electronic structure at specific sites of a molecule. The rapid reaction of protons to 1s photo-excitations can yield directional structural distortions within the femtosecond core-excited state lifetime. These directional proton dynamics can change the energetic separation of eigenstates of the system and alter probabilities for radiative decay between them. Both effects yield spectral signatures of the dynamics in RIXS spectra. Using these signatures of RIXS transitions into electronically excited states, we investigate proton dynamics induced by N K-edge excitation in the amino-acid histidine. The minor core-excited state dynamics of histidine in basic and neutral chemical environments allow us to establish XAS and RIXS spectral signatures of different N protonation states at its imidazole N sites. Based on these signatures, we identify an excitation-site-independent N-H dissociation for N K-edge excitation under acidic conditions. Such directional structural deformations, induced by core-excitations, also make proton dynamics in electronic ground states accessible through RIXS transitions into vibrationally excited states. In that context, we interpret high resolution RIXS spectra of the water molecule for three O K-edge resonances based on quantum-chemical wave packet propagation simulations. We show that highly oriented ground state vibrational modes of coupled nuclear motion can be populated through RIXS processes by preparation of core-excited state nuclear wave packets with the same directionality. Based on that, we analytically derive the possibility to extract one-dimensional directional cuts through potential energy surfaces of molecular systems from the corresponding RIXS spectra. We further verify this concept through the extraction of the gas-phase water ground state potential along three coordinates from experimental data in comparison to quantum-chemical simulations of the potential energy surface. This thesis also contains contributions to instrumentation development for investigations of photo-induced molecular dynamics at high brilliance X-ray light sources. We characterize the setup used for the transient valence-excited state XAS measurements of 2-thiopyridone. Therein, a sub-micrometer thin liquid sample environment is established employing in-vacuum flat-jet technology, which enables a transmission experimental geometry. In combination with a MHz-laser system, we achieve a high detection sensitivity for photo-induced X-ray absorption changes. Additionally, we present conceptual improvements for temporal X-ray optical cross-correlation techniques based on transient changes of multilayer optical properties, which are crucial for the realization of femtosecond time-resolved studies at synchrotrons and free-electron lasers.},
  language  = {en}
}
@phdthesis{Bauch2019,
  author    = {Bauch, Marcel},
  title     = {Untersuchungen an neuartigen sauerstoffsubstituierten Donoren und Akzeptoren f{\"u}r Singulettsauerstoff},
  doi       = {10.25932/publishup-42514},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-425140},
  school      = {Universit{\"a}t Potsdam},
  pages     = {VI, 196, xiv, A-27},
  year      = {2019},
  abstract  = {Im Verlauf dieser Arbeit wurden Aromaten wie Naphthaline und Anthracene mit Singulettsauerstoff, einer reaktiven Form des gew{\"o}hnlichen Sauerstoffs, zu sogenannten Endoperoxiden umgesetzt. Die hier eingesetzten Systeme wurden mit funktionellen Gruppen modifiziert, die {\"u}ber eine Sauerstoffbr{\"u}cke mit dem Aromaten verkn{\"u}pft sind. Die daraus entstandenen Endoperoxide sind meist besonders labil und konnten in dieser Arbeit isoliert und umfassend untersucht werden. Hierbei wurde zum einen das Reaktionsverhalten untersucht. Es konnte gezeigt werden, dass die Aromaten in Abh{\"a}ngigkeit ihrer funktionellen Gruppen unterschiedlich schnell mit Singulettsauerstoff reagieren. Die so ermittelten Reaktivit{\"a}ten wurden zus{\"a}tzlich durch theoretische Berechnungen gest{\"u}tzt. Die resultierenden Endoperoxide wurden unter verschiedenen Bedingungen wie erh{\"o}hter Temperatur oder einem sauren bzw. basischen Milieu auf ihre Stabilit{\"a}t hin untersucht. Dabei konnte gezeigt werden, dass die auf Naphthalinen basierenden Endoperoxiden den gebundenen Singulettsauerstoff in guten Ausbeuten oft schon bei sehr niedrigen Temperaturen (-40 bis 0 °C) freisetzen. Diese Verbindungen k{\"o}nnen daher als milde Quellen dieser reaktiven Sauerstoffspezies eingesetzt werden. Weiterhin konnten bei den Anthracenendoperoxiden Zerfallsmechanismen aufgekl{\"a}rt und andere reaktive Sauerstoffspezies wie Wasserstoffperoxid oder Pers{\"a}uren nachgewiesen werden. Zu den Modifikationen der Aromaten geh{\"o}ren auch Glucosereste. Dadurch k{\"o}nnten sich die hier hergestellten Endoperoxide als vielversprechende Verbindungen in der Krebstherapie herausstellen, da Krebszellen deutlich st{\"a}rker als gesunde Zellen kohlenhydratreiche Verbindungen f{\"u}r ihren Stoffwechsel ben{\"o}tigen. Bei der Spaltung von Endoperoxiden mit Glucosesubstituenten werden ebenfalls reaktive Sauerstoffspezies frei, die so zum Zelltod f{\"u}hren k{\"o}nnten.},
  language  = {de}
}
@phdthesis{Grishina2019,
  author    = {Grishina, Yulia},
  title     = {Assessing the applicability of annotation projection methods for coreference relations},
  doi       = {10.25932/publishup-42537},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-425378},
  school      = {Universit{\"a}t Potsdam},
  pages     = {viii, 198},
  year      = {2019},
  abstract  = {The main goal of this thesis is to explore the feasibility of using cross-lingual annotation projection as a method of alleviating the task of manual coreference annotation. To reach our goal, we build a first trilingual parallel coreference corpus that encompasses multiple genres. For the annotation of the corpus, we develop common coreference annotation guidelines that are applicable to three languages (English, German, Russian) and include a novel domain-independent typology of bridging relations as well as state-of-the-art near-identity categories. Thereafter, we design and perform several annotation projection experiments. In the first experiment, we implement a direct projection method with only one source language. Our results indicate that, already in a knowledge-lean scenario, our projection approach is superior to the most closely related work of Postolache et al. (2006). Since the quality of the resulting annotations is to a high degree dependent on the word alignment, we demonstrate how using limited syntactic information helps to further improve mention extraction on the target side. As a next step, in our second experiment, we show how exploiting two source languages helps to improve the quality of target annotations for both language pairs by concatenating annotations projected from two source languages. Finally, we assess the projection quality in a fully automatic scenario (using automatically produced source annotations), and propose a pilot experiment on manual projection of bridging pairs. For each of the experiments, we carry out an in-depth error analysis, and we conclude that noisy word alignments, translation divergences and morphological and syntactic differences between languages are responsible for projection errors. We systematically compare and evaluate our projection methods, and we investigate the errors both qualitatively and quantitatively in order to identify problematic cases. Finally, we discuss the applicability of our method to coreference annotations and propose several avenues of future research.},
  language  = {en}
}
@phdthesis{Kneis2019,
  author    = {Kneis, Marek},
  title     = {Die Anfechtbarkeit und die Feststellbarkeit der Mutterschaft de lege lata und de lege ferenda},
  series = {Acta Iuridica Universitatis Potsdamiensis},
  journal   = {Acta Iuridica Universitatis Potsdamiensis},
  number    = {6},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-86956-437-1},
  issn      = {2199-9686},
  doi       = {10.25932/publishup-41384},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-413843},
  school      = {Universit{\"a}t Potsdam},
  pages     = {415},
  year      = {2019},
  abstract  = {Der althergebrachte Grundsatz, wonach das Kind von der Frau abstammt, welche es geboren hat, ist durch die moderne Fortpflanzungsmedizin ins Wanken geraten. Dennoch ordnet \S 1591 BGB das Kind unanfechtbar der Geburtsmutter zu. Rechtliche und genetische Mutterschaft fallen deshalb dauerhaft auseinander, wenn das Kind im Wege der Leihmutterschaft oder nach einer Eizell- bzw. Embryospende zur Welt kommt. Die auf diese ­Methoden der artifiziellen Reproduktion bezogenen, im Inland bestehenden Verbote halten Paare mit Kinderwunsch nicht davon ab, auf entsprechende Angebote im Ausland zur{\"u}ckzugreifen. Daraus resultierende kollisions- und verfassungsrechtliche Probleme sind Gegenstand der vorliegenden Arbeit. F{\"u}r den Bereich der Leihmutterschaft wird der Frage nachgegangen, ob die mit dem Anfechtungsausschluss verfolgten Ziele des Gesetzgebers die damit einhergehenden Beeintr{\"a}chtigungen grundrechtlich gesch{\"u}tzter Rechtspositionen von genetischer Mutter und Kind rechtfertigen k{\"o}nnen. Besonderes Augenmerk liegt auf dem von Art. 6 Abs. 2 S. 1 GG gesch{\"u}tzten Interesse von leiblichen Eltern und Kindern, die verfahrensrechtliche M{\"o}glichkeit zu erhalten, rechtlich einander zugeordnet zu werden. Dieses Interesse wird den Zielen des Gesetzgebers, der mit dem Anfechtungsausschluss die Rechte von Leihm{\"u}ttern und Kindern zu sch{\"u}tzen beabsichtigt, im Rahmen einer umfassenden Verh{\"a}ltnism{\"a}ßigkeitspr{\"u}fung gegen{\"u}bergestellt. In den Konstellationen der Eizell- und Embryospende tritt schwerpunkt­m{\"a}ßig das Recht des Kindes auf Kenntnis der eigenen Abstammung in den Vordergrund und mit ihm die Frage, ob sich daraus eine Verpflichtung des Gesetzgebers ableiten l{\"a}sst, den Tatbestand von \S 1598a BGB so zu erweitern, dass die vermuteten genetischen Eltern f{\"u}r den Bereich der artifiziellen Reproduktion in den Kreis der Kl{\"a}rungsverpflichteten aufgenommen werden. Neben diesen Schwerpunkten werden viele weitere Probleme angesprochen. Im Ergebnis m{\"u}ndet die Arbeit in einen Vorschlag f{\"u}r die Legislative.},
  language  = {de}
}
@phdthesis{Ferrari2019,
  author    = {Ferrari, Camilla},
  title     = {Comparative transcriptomic studies to predict gene function and investigate the evolution of diurnal regulation},
  pages     = {147},
  year      = {2019},
  language  = {en}
}
@phdthesis{Hoerdt2019,
  author    = {H{\"o}rdt, Michael},
  title     = {Pflichtteilsrecht und EU-ErbVO},
  series = {Potsdamer Rechtswissenschaftliche Reihe ; 33},
  journal   = {Potsdamer Rechtswissenschaftliche Reihe ; 33},
  publisher = {Frank \& Timme},
  address   = {Berlin},
  isbn      = {978-3-7329-0508-9},
  pages     = {476},
  year      = {2019},
  language  = {de}
}
@phdthesis{Beckmann2019,
  author    = {Beckmann, Jens},
  title     = {Selbstverwaltung zwischen Management und »Communaut{\´e}«},
  series = {Histoire ; 148},
  journal   = {Histoire ; 148},
  publisher = {transcript},
  address   = {Bielefeld},
  isbn      = {978-3-8376-4581-1},
  school      = {Universit{\"a}t Potsdam},
  pages     = {380},
  year      = {2019},
  abstract  = {Die Besch{\"a}ftigten des franz{\"o}sischen Uhrenherstellers LIP machten 1973 europaweit Furore: Im Kampf gegen Entlassungen stellten sie Verhandlungsroutinen und Hierarchien infrage und nahmen Produktion und Verkauf von Armbanduhren in die eigene Hand. Wenige Jahre sp{\"a}ter gr{\"u}ndeten die »LIPs« mehrere Produktionsgenossenschaften. Jens Beckmann untersucht diese Auseinandersetzungen von ihren Anf{\"a}ngen bis zum Arbeitsalltag in den 1980er Jahren. Er zeigt, welche Vorstellungen von Selbstverwaltung sich hier niederschlugen, und nimmt eine gr{\"u}ndliche Kontextualisierung in Branche und Region vor - von der Revolte der 1968er Jahre bis zu Kurzarbeit und Sozialpl{\"a}nen.},
  language  = {de}
}
@phdthesis{Mai2019,
  author    = {Mai, Udo},
  title     = {La modalit{\´e} et ses r{\´e}alisations en fran{\c{c}}ais},
  series = {Potsdam Linguistic Investigations ; 26},
  journal   = {Potsdam Linguistic Investigations ; 26},
  publisher = {Lang},
  address   = {Berlin},
  isbn      = {978-3-631-73990-7},
  school      = {Universit{\"a}t Potsdam},
  pages     = {340},
  year      = {2019},
  abstract  = {L'auteur con{\c{c}}oit la modalit{\´e} comme une cat{\´e}gorie s{\´e}mantico-fonctionnelle, ind{\´e}pendante des {\´e}l{\´e}ments qui l'expriment et du niveau de la structure grammaticale dont ils rel{\`e}vent. Pour d{\´e}finir la modalit{\´e}, il tient compte {\´e}galement de ses caract{\´e}ristiques structurelles ainsi que de ph{\´e}nom{\`e}nes relevant de niveaux cognitifs plus hauts et plus bas. Cela permet de porter un regard critique sur les recherches ant{\´e}rieures, de d{\´e}velopper un cadre th{\´e}orique conciliant les diff{\´e}rentes approches et d'analyser syst{\´e}matiquement les expressions de la modalit{\´e} en fran{\c{c}}ais (verbes et adverbes modaux, modes verbaux etc.). L'interaction entre plusieurs {\´e}l{\´e}ments modaux dans le m{\^e}me {\´e}nonc{\´e} peut d{\´e}clencher trois types d'interaction et produit des ph{\´e}nom{\`e}nes modaux particuli{\`e}rement complexes.},
  language  = {fr}
}
@phdthesis{Boehne2019,
  author    = {B{\"o}hne, Sebastian},
  title     = {Different degrees of formality},
  doi       = {10.25932/publishup-42379},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-423795},
  school      = {Universit{\"a}t Potsdam},
  pages     = {VI, 167},
  year      = {2019},
  abstract  = {In this thesis we introduce the concept of the degree of formality. It is directed against a dualistic point of view, which only distinguishes between formal and informal proofs. This dualistic attitude does not respect the differences between the argumentations classified as informal and it is unproductive because the individual potential of the respective argumentation styles cannot be appreciated and remains untapped. This thesis has two parts. In the first of them we analyse the concept of the degree of formality (including a discussion about the respective benefits for each degree) while in the second we demonstrate its usefulness in three case studies. In the first case study we will repair Haskell B. Curry's view of mathematics, which incidentally is of great importance in the first part of this thesis, in light of the different degrees of formality. In the second case study we delineate how awareness of the different degrees of formality can be used to help students to learn how to prove. Third, we will show how the advantages of proofs of different degrees of formality can be combined by the development of so called tactics having a medium degree of formality. Together the three case studies show that the degrees of formality provide a convincing solution to the problem of untapped potential.},
  language  = {en}
}
@phdthesis{JadhavSudam2019,
  author    = {Jadhav Sudam, Sagar},
  title     = {Metabolic regulation and key genes of tomato secondary metabolism},
  doi       = {10.25932/publishup-42447},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-424478},
  school      = {Universit{\"a}t Potsdam},
  pages     = {x, 149},
  year      = {2019},
  abstract  = {Domestication syndrome has resulted in the large loss of genetic variation of crop plants. Because of such genetic loss, productivity of various beneficial secondary (specialized) metabolites that protect against abiotic/biotic stresses, has been narrowed in many domesticated crops. Many key regulators or structural genes of secondary metabolic pathways in the domesticated as well as wild tomatoes are still largely unknown. In recent studies, metabolic quantitative trait loci (mQTL) analysis using the population of introgression lines (ILs), each containing a single introgression from Solanum pennellii (wild tomato) in the genetic background of domesticated tomato (M82, Solanum lycopersicum), has been used for investigation of metabolic regulation and key genes involved in both primary and secondary metabolism. In this thesis, three research projects, i) understanding of metabolic linkage between branched chain amino acids (BCAAs) and secondary metabolism using antisense lines of BCAAs metabolic genes, ii) investigation of novel key genes involved in tomato secondary metabolism and fruit ripening, iii) mapping of drought stress responsive mQTLs in tomato, are presented and discussed. In the first part, metabolic linkage between leucine and secondary metabolism is investigated by analyzing antisense lines of four key genes (ketol-acid reductoisomerase, KARI; dihydroxy-acid dehydratase, DHAD; isopropylmalate dehydratase, IPMD and branched chain aminotransferases1, BCAT1) found previously in mQTL of leucine contents. Obtained results indicate that KARI might be a rate limiting enzyme for iC5 acyl-sucrose synthesis in young leaf but not in red ripe fruits. By integrating obtained results with previous reports, inductive metabolic linkage between BCAAs and other secondary metabolic pathways at DHAD transcriptional levels in fruit is proposed. In the second part, candidate genes that are involved in secondary metabolism and fruit ripening in tomato were found by the approach of expression quantitative trait loci (eQTL) analysis. To predict functions of those candidate genes, functional validation by virus induced gene silencing and transient overexpression were performed. Results obtained by analyzing T0 overexpression and artificial miRNA lines for some of those candidates confirm their predicted functions, for example involved in fruit ripening (WD40, Solyc04g005020) and iC5 acyl-sucrose synthesis (P450, Solyc03g111940). In the third part, mapping of drought stress responsive mQTLs was performed using 57 S. pennellii ILs population. Evaluation of genetic architecture of mQTL analysis resulted in identifying drought responsive ILs (11-2, 8-3-1, 10-1-1 and 3-1). Location of well characterized regulators in these ILs helped to filter potential new key genes involved in drought stress tolerance. Obtained results suggests us our approaches could be viable for narrowing down potential candidates involved in creating interspecific variation in secondary metabolite content and at the level of fruit ripening.},
  language  = {en}
}
@phdthesis{Brandt2019,
  author    = {Brandt, Christopher Georg},
  title     = {"… when the legend becomes fact …"},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-86956-429-6},
  doi       = {10.25932/publishup-41044},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-410441},
  school      = {Universit{\"a}t Potsdam},
  pages     = {377},
  year      = {2019},
  abstract  = {Der historische Spielfilm z{\"a}hlt zu den popul{\"a}rsten Formen geschichtskultureller Artikulation. Als solche ist er Gegenstand kontroverser Diskussionen {\"u}ber einen angemessenen didaktischen Umgang. Vor diesem Hintergrund ist es das Ziel der vorliegenden Arbeit, ein integratives, theoretisch und empirisch abgesichertes Analysemodell zu entwickeln, das nach den Tiefenstrukturen historischen Erz{\"a}hlens im Medium des Spielfilms fragt und dabei unterschiedliche Erscheinungsformen historischer Spielfilme ber{\"u}cksichtigt. Die {\"U}berlegungen bewegen sich deshalb in einem interdisziplin{\"a}ren Spannungsfeld von Theorien zum historischen Erz{\"a}hlen und Konzepten der Literatur- und Filmwissenschaft. Die Diskussion und Synthese dieser unterschiedlichen Konzepte geht dabei - auf der Grundlage einer großen Materialbasis - vom Gegenstand aus und ist induktiv angelegt. Als Orientierung f{\"u}r die praktische Arbeit werden am Ende der einzelnen Kapitel Toolkits entwickelt, die zu einer vertieften Auseinandersetzung mit historischen Spielfilmen anregen sollen.},
  language  = {de}
}
@phdthesis{Wolf2019,
  author    = {Wolf, Mathias Johannes},
  title     = {The role of partial melting on trace element and isotope systematics of granitic melts},
  doi       = {10.25932/publishup-42370},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-423702},
  school      = {Universit{\"a}t Potsdam},
  pages     = {iv, 129},
  year      = {2019},
  abstract  = {Partial melting is a first order process for the chemical differentiation of the crust (Vielzeuf et al., 1990). Redistribution of chemical elements during melt generation crucially influences the composition of the lower and upper crust and provides a mechanism to concentrate and transport chemical elements that may also be of economic interest. Understanding of the diverse processes and their controlling factors is therefore not only of scientific interest but also of high economic importance to cover the demand for rare metals. The redistribution of major and trace elements during partial melting represents a central step for the understanding how granite-bound mineralization develops (Hedenquist and Lowenstern, 1994). The partial melt generation and mobilization of ore elements (e.g. Sn, W, Nb, Ta) into the melt depends on the composition of the sedimentary source and melting conditions. Distinct source rocks have different compositions reflecting their deposition and alteration histories. This specific chemical "memory" results in different mineral assemblages and melting reactions for different protolith compositions during prograde metamorphism (Brown and Fyfe, 1970; Thompson, 1982; Vielzeuf and Holloway, 1988). These factors do not only exert an important influence on the distribution of chemical elements during melt generation, they also influence the volume of melt that is produced, extraction of the melt from its source, and its ascent through the crust (Le Breton and Thompson, 1988). On a larger scale, protolith distribution and chemical alteration (weathering), prograde metamorphism with partial melting, melt extraction, and granite emplacement are ultimately depending on a (plate-)tectonic control (Romer and Kroner, 2016). Comprehension of the individual stages and their interaction is crucial in understanding how granite-related mineralization forms, thereby allowing estimation of the mineralization potential of certain areas. Partial melting also influences the isotope systematics of melt and restite. Radiogenic and stable isotopes of magmatic rocks are commonly used to trace back the source of intrusions or to quantify mixing of magmas from different sources with distinct isotopic signatures (DePaolo and Wasserburg, 1979; Lesher, 1990; Chappell, 1996). These applications are based on the fundamental requirement that the isotopic signature in the melt reflects that of the bulk source from which it is derived. Different minerals in a protolith may have isotopic compositions of radiogenic isotopes that deviate from their whole rock signature (Ayres and Harris, 1997; Knesel and Davidson, 2002). In particular, old minerals with a distinct parent-to-daughter (P/D) ratio are expected to have a specific radiogenic isotope signature. As the partial melting reaction only involves selective phases in a protolith, the isotopic signature of the melt reflects that of the minerals involved in the melting reaction and, therefore, should be different from the bulk source signature. Similar considerations hold true for stable isotopes.},
  language  = {en}
}
@phdthesis{AlNakeeb2019,
  author    = {Al Nakeeb, Noah},
  title     = {Self-assembly and crosslinking approaches of double hydrophilic linear-brush block copolymers},
  pages     = {133},
  year      = {2019},
  language  = {en}
}
@phdthesis{Kuecuekgoeze2019,
  author    = {K{\"u}{\c{c}}{\"u}kg{\"o}ze, G{\"o}khan},
  title     = {Purification and characterization of mouse aldehyde oxidases},
  school      = {Universit{\"a}t Potsdam},
  pages     = {xiv, 125},
  year      = {2019},
  abstract  = {Mouse aldehyde oxidases (mAOXs) have a homodimeric structure and belong to xanthine oxidase family of molybdo-flavoenzymes. In general, each dimer is characterized by three subdomains: a 20 kDa N-terminal 2x[2Fe2S] cluster containing domain, a 40 kDa central FAD-containing domain and an 85 kDa C-terminal molybdenum cofactor (Moco) containing domain. Aldehyde oxidases have a broad substrate specificity including the oxidation of different aldehydes and N-heterocyclic compounds. AOX enzymes are present in mainly all eukaryotes. Four different homologs of AOX were identified to be present with varying numbers among species and rodents like mice and rats contain the highest number of AOX isoenzymes. There are four identified homologs in mouse named mAOX1, mAOX3, mAOX2, and mAOX4. The AOX homologs in mice are expressed in a tissue-specific manner. Expression of mAOX1 and mAOX3 are almost superimposable and predominantly synthesized in liver, lung, and testis. The richest source of mAOX4 is the Harderian gland, which is found within the eye's orbit in tetrapods. Expression of mAOX2 is strictly restricted to the Bowman's gland, the main secretory organ of the nasal mucosa. In this study, the four catalytically active mAOX enzymes were expressed in a heterologous expression system in Escherichia coli and purified in a catalytically active form. Thirty different structurally related aromatic, aliphatic and N-heterocyclic compounds were used as substrates, and the kinetic parameters of all four mAOX enzymes were directly compared. The results showed that all enzymes can catalyze a broad range of substrates. Generally, no major differences between mAOX1, mAOX3 and mAOX2 were identified and the substrate specificity of mAOX1, mAOX3, and mAOX2 was broader compared to that of mAOX4 since mAOX4 showed no activity with substrates like methoxy-benzaldehydes, phenanthridine, N1-methyl-nicotinamide, and cinnamaldehyde and 4-(dimethylamino)cinnamaldehyde. We investigated differences at the flavin site of the mAOX enzymes by measuring the ability of the four mAOX enzymes to oxidize NADH in the absence of oxygen. NADH was able to reduce only mAOX3. The four mouse AOXs are also characterized by quantitative differences in their ability to produce superoxide radicals. mAOX2 is the enzyme generating the largest rate of superoxide radicals of around 40\% in relation to moles of substrate converted and it is followed by mAOX1 with a ratio of 30\%. To understand the factors that contribute to the substrate specificity of mAOX4, site-directed mutagenesis was applied to substitute amino acids in the substrate-binding funnel by the ones present in mAOX1, mAOX3, and mAOX2. The amino acids Val1016, Ile1018 and Met1088 were selected as targets. An increase in activity was obtained by the amino acid exchange M1088V in the active site identified to be specific for mAOX4, to the amino acid identified in mAOX3.},
  language  = {en}
}
@phdthesis{Hoffmann2019,
  author    = {Hoffmann, Mathias},
  title     = {Improving measurement and modelling approaches of the closed chamber method to better assess dynamics and drivers of carbon based greenhouse gas emissions},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-421302},
  school      = {Universit{\"a}t Potsdam},
  pages     = {xx, 204, xxix},
  year      = {2019},
  abstract  = {The trace gases CO2 and CH4 pertain to the most relevant greenhouse gases and are important exchange fluxes of the global carbon (C) cycle. Their atmospheric quantity increased significantly as a result of the intensification of anthropogenic activities, such as especially land-use and land-use change, since the mid of the 18th century. To mitigate global climate change and ensure food security, land-use systems need to be developed, which favor reduced trace gas emissions and a sustainable soil carbon management. This requires the accurate and precise quantification of the influence of land-use and land-use change on CO2 and CH4 emissions. A common method to determine the trace gas dynamics and C sink or source function of a particular ecosystem is the closed chamber method. This method is often used assuming that accuracy and precision are high enough to determine differences in C gas emissions for e.g., treatment comparisons or different ecosystem components. However, the broad range of different chamber designs, related operational procedures and data-processing strategies which are described in the scientific literature contribute to the overall uncertainty of closed chamber-based emission estimates. Hence, the outcomes of meta-analyses are limited, since these methodical differences hamper the comparability between studies. Thus, a standardization of closed chamber data acquisition and processing is much-needed. Within this thesis, a set of case studies were performed to: (I) develop standardized routines for an unbiased data acquisition and processing, with the aim of providing traceable, reproducible and comparable closed chamber based C emission estimates; (II) validate those routines by comparing C emissions derived using closed chambers with independent C emission estimates; and (III) reveal processes driving the spatio-temporal dynamics of C emissions by developing (data processing based) flux separation approaches. The case studies showed: (I) the importance to test chamber designs under field conditions for an appropriate sealing integrity and to ensure an unbiased flux measurement. Compared to the sealing integrity, the use of a pressure vent and fan was of minor importance, affecting mainly measurement precision; (II) that the developed standardized data processing routines proved to be a powerful and flexible tool to estimate C gas emissions and that this tool can be successfully applied on a broad range of flux data sets from very different ecosystem; (III) that automatic chamber measurements display temporal dynamics of CO2 and CH4 fluxes very well and most importantly, that they accurately detect small-scale spatial differences in the development of soil C when validated against repeated soil inventories; and (IV) that a simple algorithm to separate CH4 fluxes into ebullition and diffusion improves the identification of environmental drivers, which allows for an accurate gap-filling of measured CH4 fluxes. Overall, the proposed standardized data acquisition and processing routines strongly improved the detection accuracy and precision of source/sink patterns of gaseous C emissions. Hence, future studies, which consider the recommended improvements, will deliver valuable new data and insights to broaden our understanding of spatio-temporal C gas dynamics, their particular environmental drivers and underlying processes.},
  language  = {en}
}
@phdthesis{Muelling2019,
  author    = {M{\"u}lling, Eric},
  title     = {Big Data und der digitale Ungehorsam},
  publisher = {Springer VS},
  address   = {Wiesbaden},
  isbn      = {978-3-658-24158-2},
  pages     = {XV, 242},
  year      = {2019},
  language  = {de}
}
@phdthesis{Apostolow2019,
  author    = {Apostolow, Markus},
  title     = {Der "immerw{\"a}hrende Staatssekret{\"a}r"},
  series = {Die Rosenburg : Schriften zur Geschichte des BMJ und der Justiz in der fr{\"u}hen Bundesrepublik},
  journal   = {Die Rosenburg : Schriften zur Geschichte des BMJ und der Justiz in der fr{\"u}hen Bundesrepublik},
  number    = {1},
  publisher = {Vandenhoeck \& Ruprecht},
  address   = {G{\"o}ttingen},
  school      = {Universit{\"a}t Potsdam},
  pages     = {366},
  year      = {2019},
  abstract  = {Als erster Staatssekret{\"a}r des 1949 gegr{\"u}ndeten Bundesministeriums der Justiz war Walter Strauß maßgeblich f{\"u}r dessen personellen Aufbau verantwortlich. W{\"a}hrend seiner Amtszeit, die erst 1963 endete, diente Strauß unter f{\"u}nf verschiedenen Ministern. Damit verk{\"o}rperte er die Kontinuit{\"a}t der Arbeit und galt nicht von ungef{\"a}hr als der eigentliche 'Herrscher der Rosenburg', dem Bonner Amtssitz des Ministeriums. Durch seinen F{\"u}hrungsstil, der die Forderung nach Qualit{\"a}t mit einem geradezu paternalistischen Verantwortungsgef{\"u}hl verband, pr{\"a}gte der Gr{\"u}ndungsstaatssekret{\"a}r den Geist des Hauses f{\"u}r lange Zeit. Obwohl er j{\"u}discher Herkunft war und im Nationalsozialismus zum Kreis der rassisch Verfolgten geh{\"o}rt hatte, griff Strauß bei der Auswahl des Personals allerdings in hohem Maße auf die Mitarbeit von Personen zur{\"u}ck, die durch ihre T{\"a}tigkeit im 'Dritten Reich' belastet waren. Warum dies so war, sucht der Autor nicht nur anhand biografischer Pr{\"a}gungen, die Strauß im Kaiserreich, in der Weimarer Republik, dem Nationalsozialismus und der Besatzungszeit erfahren hatte, sondern auch durch eine umfassende Darstellung der wesentlichen Merkmale und Kennzeichen seiner Personalpolitik zu ergr{\"u}nden: Wie weit reichte sein Einfluss Welche Rolle spielte er bei Auswahl und Bef{\"o}rderungen, in erster Linie der Beamten des h{\"o}heren Dienstes, in Abgrenzung zu anderen Akteuren Und in welchem Maße war er bei seinen Entscheidungen durch institutionelle Rahmenbedingungen eingeschr{\"a}nkt 366 pp},
  language  = {de}
}